Genes & Diseases

Papers
(The TQCC of Genes & Diseases is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes1124
Ubiquitination and degradation of SIK2 by DNA-PKcs deficiency promote radiation-induced mitotic catastrophe285
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility261
Clinical management of a rare melanoma case arising from congenital melanocytic nevus147
Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination145
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice135
Exploring the role of FTO in preeclampsia pathogenesis: Insights into m6A modification and decidualization132
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice118
Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)109
Expanded insights into the mechanisms of RNA-binding protein regulation of circRNA generation and function in cancer biology and therapy105
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer94
The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development93
The role of TGF-β in the tumor microenvironment of pancreatic cancer87
BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response81
DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis81
The advancements in organoids: Potential and challenges in researching the esophagus and esophageal squamous cell carcinoma78
Autoantigenic peptide landscape of rheumatoid arthritis-associated HLA class II77
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma77
Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression76
Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation75
Integrative analysis reveals the clinical utility of cancer-associated fibroblast-derived signature, and its implication for young-onset thyroid cancer74
Patient-derived xenograft models: Current status, challenges, and innovations in cancer research69
lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology65
Wnt genes in colonic polyposis predisposition63
Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia63
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis62
Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis60
Epigenetics: Mechanisms, potential roles, and therapeutic strategies in cancer progression58
Phenotypic characterization of patients with activated PI3Kδ syndrome 1 presenting with features of systemic lupus erythematosus56
Mechanism of PARP inhibitor resistance and potential overcoming strategies55
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells54
The implication of pyroptosis in cancer immunology: Current advances and prospects52
Development of an orally bioavailable selective inhibitor of the menin-MLL52
A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response52
Loss of homeostatic functions in microglia from a murine model of Friedreich's ataxia50
Mitochondrial transplantation in lung diseases: From mechanisms to application prospects47
Platinum-resistant ovarian cancer: From mechanisms to treatment strategies47
A peptide-based assay discriminates individual antibody response to SARS-CoV-246
EBF1 expressed in the dermal papilla regulates hair type and length45
PD-L1 expression and smoke exposure as biomarkers for optimizing adjuvant therapy for patients with resected limited-stage small-cell lung carcinoma45
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target45
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration45
HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy45
Defective biological networks associated with pseudogene-derived lncRNAs in cancer drug resistance: Promising prospects for their clinical targets in cancer therapy44
Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis44
Sirolimus may improve bile excretion in ABCB11 mutants: A case report of a patient with bile salt export pump deficiency43
Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines42
PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells42
MACF1 deficiency suppresses tooth mineralization through IGF1 mediated crosstalk between odontoblasts and ameloblasts42
Co-localization of TAZ and H2A.Z up-regulates IL-6 expression in alveolar epithelial cells to polarize M2 cells to alleviate hypoxia-induced lung injury41
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization41
AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo40
BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations40
A focused transcriptomic analysis of the TP53-regulated genes identifies the GPI-anchored molecule-like protein (GML) as a favorable prognostic predictor of lung cancer39
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer39
The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype38
Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma37
Hippo-YAP/TAZ signaling in breast cancer: Reciprocal regulation of microRNAs and implications in precision medicine37
Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis37
Tirzepatide, a dual GIP/GLP-1 receptor agonist, alleviates metabolic dysfunction-associated steatotic liver disease by reducing the expression of CD36 and OBP2A36
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodont36
Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma36
LncRNA KCNQ1OT1: Molecular mechanisms and pathogenic roles in human diseases35
Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation34
Single-cell analysis reveals the lncRNA-MEG3/miRNA-133a-3p/PRRT2 axis regulates skeletal muscle regeneration and myogenesis33
DNA methylation drives a new path in gastric cancer early detection: Current impact and prospects32
Publisher’s Note32
The USP7 protein interaction network and its roles in tumorigenesis32
[18F]florbetapir PET for early detection of amyloidosis in patients with hereditary transthyretin amyloidosis polyneuropathy32
Reduction of Atp5b protects mice from diet-induced obesity32
The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections32
Inhibition of VEGFR2 overcomes venetoclax-resistance in diffuse large B-cell lymphoma cells32
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio32
The 21-base pair deletion mutant Calpain3 does not inhibit wild-type Calpain3 activity32
Hypermethylation of the ALOX12 and CBS promoters in osteoporosis: Potential biomarkers for early diagnosis31
Integrative high-throughput studies to develop novel targets and drugs for the treatment of advanced prostate cancer30
3′-UTR of the SARS-CoV-2 genome as a possible source of piRNAs30
Pseudotyped lentiviral vectors: Ready for translation into targeted cancer gene therapy?30
Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance30
Identification and functional characterization of a novel nonsense mutation of CASR gene in a familial hypocalciuric hypercalcemia pedigree30
Lactate transporter MCT4 regulates the hub genes for lipid metabolism and inflammation to attenuate intracellular lipid accumulation in non-alcoholic fatty liver disease29
Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma28
Cerebral furin deficiency causes hydrocephalus in mice28
MiR-743a-5p regulates differentiation of myoblast by targeting Mob1b in skeletal muscle development and regeneration28
Immune patterns of the tumor microenvironment in PD-L1+ EGFR+ HNSCC patients received anti-PD-1 and EGFR-based neoadjuvant therapy28
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling28
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family27
Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity27
Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis27
The genomic and epigenomic landscape of iridocorneal endothelial syndrome27
Hypoxia-induced m6A demethylation promotes hepatocellular carcinoma progression by preventing the degradation of Gal-1 mRNA27
CMTM3 suppresses bone formation and osteogenic differentiation of mesenchymal stem cells through inhibiting Erk1/2 and RUNX2 pathways27
Unraveling the role of the WIPF1/ACTN4 complex in podosome formation of human placental EVTs: Insights into recurrent spontaneous abortion26
The paradoxical functions of long noncoding RNAs in hepatocellular carcinoma: Implications in therapeutic opportunities and precision medicine26
SPINOPHILIN: A multiplayer tumor suppressor26
A novel mutation in KDR is associated with retinal venous beading and cerebral cavernous malformation26
Emerging role of SETD2 in the development and function of immune cells26
MPDZ variants associated with epilepsies and/or febrile seizures and the individualized genotype-phenotype correlation25
Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways25
The therapeutic effect of nicotinamide riboside chloride on ameliorating alcohol-induced neuronal damage with a focus on mitochondrial unfolded protein response and mitophagy25
Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies25
Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance24
Transcriptomic analysis identifies a pan-cancer association of IL27 expression with cancer prognosis and immune microenvironment24
Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patients24
Vault RNAs (vtRNAs): Rediscovered non-coding RNAs with diverse physiological and pathological activities24
AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders24
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma24
Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children24
Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses24
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis24
The germline genetics of mild-to-moderate penetrance: An intriguing role of PRAME in multiple carcinogenesis23
HSP90B1 facilitates glioma radiotherapy resistance by regulating RhoC ubiquitin‒proteasome degradation23
A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis23
Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy23
Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera23
Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells23
Co-alteration of Myc and RTK-RAS pathways defines a liver-metastatic propensity and immune-cold subgroup of pancreatic adenocarcinoma22
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 422
Low expression of OXCT1 promote colorectal cancer liver metastasis by upregulating CDK8 and β-catenin via H3 acetylation22
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes21
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice21
New insights into the suppression of inflammation and lipid accumulation by JAZF121
Dlc1 deletion activates the canonical Wnt pathway at an early stage and affects subsequent cardiac differentiation in mouse embryonic stem cells21
Nucleolin promotes tumor growth in colorectal cancer by enhancing hnRNPA1-mediated PKM2 alternative splicing21
Nidogen: A matrix protein with potential roles in musculoskeletal tissue regeneration21
Hydrogen sulfide-induced post-translational modification as a potential drug target21
Downregulation of nc886 contributes to prostate cancer cell invasion and TGFβ1-induced EMT21
Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration20
Characterization of the molecular dysfunctions occurring in Aicardi-Goutières syndrome patients with mutations in ADAR120
Regulation mechanism and pathogenic role of lncRNA plasmacytoma variant translocation 1 (PVT1) in human diseases20
Targeting MYC: Multidimensional regulation and therapeutic strategies in oncology20
Context-dependent actions of STING pathway in colitis and associated colon cancer20
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth20
CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma20
The generation and use of animal models of osteosarcoma in cancer research20
Increased N6-methyladenosine is related to the promotion of the methyltransferase METTL14 in ovarian aging20
Upregulated Krüppel-like factor 5 promotes hepatocellular carcinoma progression by activating Wnt3a signaling20
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC)20
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead20
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosis19
Elevation of TRIM44 potentiates propagation of gastric cancer stem cells19
Corrigendum to “Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression” [Genes & Diseases 11 (2024) 919
Single-cell spatial transcriptomics in cardiovascular development, disease, and medicine19
Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants19
Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression19
The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases19
Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development19
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy19
Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells18
Emerging roles for fatty acid oxidation in cancer18
RETRACTED: Corrigendum to “Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4” [Genes Dis DOI: 10.118
A lncRNA MEG3 variant enhances telomerase activity by increasing DNA damage repair ability in human liver cancer stem cells18
Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation18
Cardiac regeneration: Pre-existing cardiomyocyte as the hub of novel signaling pathway18
The key mediator of diabetic kidney disease: Potassium channel dysfunction18
Mutations in GTPBP3 cause aberrant mitochondrial respiration associated with combined oxidative phosphorylation deficiency 2318
Arhgap29 deficiency causes EEC like syndrome in mice18
N6-methyladenosine-modified circLPAR3 Drives Docetaxel Resistance in Prostate Cancer by Suppressing Ferroptosis Through the PCBP2/CHAC1 Axis18
Genetic and immunologic characteristics of colorectal cancer patients with KRAS mutations and predictive significance of tumor immune microenvironment in adjuvant chemotherapy18
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus18
The role of regulators of RNA m6A methylation in lung cancer18
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways18
Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting18
Corrigendum to “Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade” [Genes & Dis 12 (2025) 101450]17
The impact of broad glutamine metabolism inhibition on the tumor microenvironment17
Construction of a novel six-gene signature to predict tumour response to induction chemotherapy and overall survival in locoregionally advanced laryngeal and hypopharyngeal carcinoma17
In vivo production of CAR T cell: Opportunities and challenges17
Blockage of SUMO E1 enzyme inhibits ocular lens fibrosis by mediating SMAD4 SUMOylation17
The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers17
PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma17
Circulating and non-circulating proteins and nucleic acids as biomarkers and therapeutic molecules in ovarian cancer17
Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia17
The functions of FXYD family members in human health and disease17
The role of m6A RNA methylation in autoimmune diseases: Novel therapeutic opportunities17
Osteoarthritis versus psoriasis arthritis: Physiopathology, cellular signaling, and therapeutic strategies17
Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment17
Single-cell RNA sequencing in juvenile idiopathic arthritis16
MMP-9 deficiency accelerates the progress of periodontitis16
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α16
Identification of TP53 mutation-associated prognostic genes and investigation of the immune cell infiltration in patients with hepatocellular carcinoma16
Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin16
Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor16
Genetic association analysis-based networks and classification of human UCP1 polymorphisms16
Alterations in expression and localization of POMGNT1 in the APP/PS1 mouse model of Alzheimer's disease16
X26nt-mediated recruitment of eIF4A2 facilitates CCND1 translation to drive endothelial cell cycle progression16
IL-17 signaling pathway in SPP1+ macrophages drives digestive tract cancer progression16
Identification of immune cell infiltration pattern in diabetic nephropathy16
Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies16
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERα expression in triple-negative breast cancer16
Genetics, epidemiology and management of clubfoot and related disorders16
The role of RGS12 in tissue repair and human diseases16
Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer15
Identification of TMEM217 as a novel prognostic biomarker and potential therapeutic target in acute myeloid leukemia15
XBP1 splicing contributes to endoplasmic reticulum stress-induced human islet amyloid polypeptide up-regulation15
MyoAAV-delivered sup-tRNA increases full-length dystrophin expression15
BET bromodomain inhibitor JQ1 regulates spermatid development by changing chromatin conformation in mouse spermatogenesis15
Novel virulence-related genes that contribute to clinical infections of Salmonella enteritidis15
lncRNA POU3F3 promotes osteosarcoma progression through GPX4-modulated ferroptosis by interaction with IGF2BP2 to facilitate NRF2 mRNA stability15
The landscape of UBE2S in hepatocellular carcinoma: Prognostic significance, immuno-oncology feature and drug response15
Establishment of a mouse model of respiratory mycoplasma challenged intranasally combined intraperitoneally eliciting chronic inflammation and lung consolidation15
Nrf2: A key regulator in chemoradiotherapy resistance of osteosarcoma14
Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy14
Prognosis prediction and immune microenvironment features of breast cancer indicated by a cuproptosis-associated long non-coding RNA signature14
Studies on the fat mass and obesity-associated (FTO) gene and its impact on obesity-associated diseases14
The role and potential therapeutic intervention of cellular senescence in intervertebral disc degeneration14
The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases14
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery14
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 414
Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective14
A novel truncating variant in PRDM16 causes severe familial cardiomyopathy with variable clinical presentations14
Profiling of histone H3 trimethylation and distinct epigenetic pattern of chromosome Y in the transformed bronchial epithelial cells induced by consecutive arsenic treatment14
High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway14
Salt-inducible kinase 1 is a key gene in suppressing EVD68-induced asthma by modulating antiviral immunity14
Single-cell RNA sequencing reveals tumor microenvironment characteristics in ovarian malignant Brenner tumor14
Comprehensive analysis and experimental verification of the role of mitochondrial dynamics-related genes in liver hepatocellular carcinoma14
The crosstalk between non-coding RNAs and oxidative stress in cancer progression14
Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine14
Calcineurin in development and disease13
A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis13
Role of lncRNA MALAT1 in UVA-induced corneal endothelial senescence13
Pan-cancer analysis of MET mutation and its association with the efficacy of immune checkpoint blockade13
Simple gene knockout by single gene-directed multiplex CRISPR-Cpf113
ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc13
Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance13
Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes13
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]13
Compound heterozygous mutations in BBS7 cause kidney abnormalities in Bardet-Biedl syndrome13
Performance analysis of markers for prostate cell typing in single-cell data13
Exosomal long non-coding RNAs: Emerging players in cancer metastasis and potential diagnostic biomarkers for personalized oncology13
Predictive value of T cell receptor repertoire profiling for immunosuppressive therapy in severe aplastic anemia13
Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies13
Decoding the impact of gut microbiota on heart failure13
Update on R-loops in genomic integrity: Formation, functions, and implications for human diseases13
The role of lncRNAs in AKI and CKD: Molecular mechanisms, biomarkers, and potential therapeutic targets12
Long noncoding RNA (lncRNA) HOTAIR: Pathogenic roles and therapeutic opportunities in gastric cancer12
The landscape of epigenetic regulation and therapeutic application of N6-methyladenosine modifications in non-coding RNAs12
Phase I trial of human umbilical cord-derived mesenchymal stem cells for treatment of severe bronchopulmonary dysplasia12
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants12
Correspondence (reply): The application conditions of false discovery rate control12
mTOR pathway: A key player in diabetic nephropathy progression and therapeutic targets12
Myelin protein zero (P0)- and Wnt1-Cre marked muscle resident neural crest-derived mesenchymal progenitor cells give rise to heterotopic ossification in mouse models12
DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer12
CCT2 enhances c-Myc stabilization to drive tumor progression and chemoresistance in head and neck squamous cell carcinoma12
BAF45D regulates spinal cord neural stem/progenitor cell fate through the SMAD-PAX6 axis12
lncRNA ADAMTS9-AS2/let-7a-5p axis regulates metabolic reprogramming by targeting HK2 in oral submucous fibrosis-associated oral squamous cell carcinoma12
MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells12
Targeting LIF/LIFR signaling in cancer12
PDLIM1 sustains DNA damage response by promoting chromatin relaxation and activating DNA–PK complex11
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics11
A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo11
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