Genes & Diseases

Article	Citations
PTEN-induced putative kinase 1 regulates mitochondrial quality control and is essential for the maturation of human induced pluripotent stem cell-derived cardiomyocytes	712
lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology	344
Effects of extracellular vesicle-derived noncoding RNAs on pre-metastatic niche and tumor progression	226
BET inhibitors enhance the anti-cancer effect of etoposide by suppressing the MRN-ATM axis in the DNA damage response	203
Sex hormone-binding globulin impedes hepatocellular carcinoma growth via MERTK regulation	103
Ubiquitination and degradation of SIK2 by DNA-PKcs deficiency promote radiation-induced mitotic catastrophe	101
Multi-omics analysis to identify CBR3-AS1-hsa-miR-145-5p-MAP3K5 pathway as a ferroptosis-related ceRNA network in benign prostatic hyperplasia	100
Atm deficient zebrafish model reveals conservation of the tumour suppressor function and a role in fertility	88
Clinical management of a rare melanoma case arising from congenital melanocytic nevus	82
Phenotypic characterization of patients with activated PI3Kδ syndrome 1 presenting with features of systemic lupus erythematosus	81
CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice	79
Development of an orally bioavailable selective inhibitor of the menin-MLL	77
Patient-derived xenograft models: Current status, challenges, and innovations in cancer research	76
Deletion of Axin1 in aggrecan-expressing cells leads to growth plate cartilage defects in adult mice	72
Regulation of SLC7A11 as an unconventional checkpoint in tumorigenesis through ferroptosis	71
The implication of pyroptosis in cancer immunology: Current advances and prospects	70
Liver-brain axis with alcohol: Role of fibroblast growth factor 21 (FGF21)	65
The molecular genetics of PI3K/PTEN/AKT/mTOR pathway in the malformations of cortical development	64
Wnt genes in colonic polyposis predisposition	63
Tryptophan attenuates acute hypoxic stress-induced intestinal injury through the modulation of intestinal barrier integrity and gut microbiota homeostasis	62
Epigenetics: Mechanisms, potential roles, and therapeutic strategies in cancer progression	61
DNA damage chemotherapeutic drugs suppress basal-like breast cancer growth by down-regulating the transcription of the FOXO1-KLF5 axis	61
Mechanism of PARP inhibitor resistance and potential overcoming strategies	60
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells	59
SETDB1-mediated CD147-K71 di-methylation promotes cell apoptosis in non-small cell lung cancer	54

Macrophage RGS12 contributes to osteoarthritis pathogenesis through enhancing the ubiquitination	51
The role of TGF-β in the tumor microenvironment of pancreatic cancer	50
The biological roles and molecular mechanisms of m6A reader IGF2BP1 in the hallmarks of cancer	48
Overactivation of histone deacetylases and EZH2 in Wilms tumorigenesis	47
Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines	47
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface: Towards a pre-clinical model of periodontal diseases and personalized periodont	47
MACF1 deficiency suppresses tooth mineralization through IGF1 mediated crosstalk between odontoblasts and ameloblasts	46
Dynamic human retinal pigment epithelium (RPE) and choroid architecture based on single-cell transcriptomic landscape analysis	46
LncRNA KCNQ1OT1: Molecular mechanisms and pathogenic roles in human diseases	45
BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations	43
The miR-21-5p enriched in the apoptotic bodies of M2 macrophage-derived extracellular vesicles alleviates osteoarthritis by changing macrophage phenotype	42
The transcriptional regulators of virulence for Pseudomonas aeruginosa: Therapeutic opportunity and preventive potential of its clinical infections	40
The USP7 protein interaction network and its roles in tumorigenesis	40
Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma	40
AAV6 as an effective gene delivery vector for prolonged transgene expression in intervertebral disc cells in vivo	39
PD-L1 expression and smoke exposure as biomarkers for optimizing adjuvant therapy for patients with resected limited-stage small-cell lung carcinoma	39
A peptide-based assay discriminates individual antibody response to SARS-CoV-2	39
EBF1 expressed in the dermal papilla regulates hair type and length	38
Loss of homeostatic functions in microglia from a murine model of Friedreich's ataxia	38
A focused transcriptomic analysis of the TP53-regulated genes identifies the GPI-anchored molecule-like protein (GML) as a favorable prognostic predictor of lung cancer	37
PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells	37
HBV sL13H mutation impairs its surface antigen expression and ability to induce autophagy	36
Alternative splicing of immune-related genes identifies breast cancer subtypes with differential immune cell infiltration	36
Heavy mechanical force decelerates orthodontic tooth movement via Piezo1-induced mitochondrial calcium down-regulation	35
Disulfidptosis heterogeneity in breast cancer uncovers PTTG1IP as an actionable therapeutic target	34
Inhibition of sphingosine 1-phosphate receptor 3 ameliorates bleomycin-induced pulmonary fibrosis by suppressing macrophage M2 polarization	34
Sirolimus may improve bile excretion in ABCB11 mutants:A case report of a patient with bile salt export pump deficiency	34
Does epigenetics have a role in age related macular degeneration and diabetic retinopathy?	34
Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma	33
Hippo-YAP/TAZ signaling in breast cancer: Reciprocal regulation of microRNAs and implications in precision medicine	33
DNA methylation drives a new path in gastric cancer early detection: Current impact and prospects	32
Single-cell analysis reveals the lncRNA-MEG3/miRNA-133a-3p/PRRT2 axis regulates skeletal muscle regeneration and myogenesis	32
The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases	31
A heterozygous N-terminal truncation mutation of NFKBIA results in an impaired NF-κB dependent inflammatory response	31
Development of novel osteoarthritis therapy by targeting AMPK-β-catenin-Runx2 signaling	30
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis	30
Cerebral furin deficiency causes hydrocephalus in mice	29
STIM1 promotes acquired resistance to sorafenib by attenuating ferroptosis in hepatocellular carcinoma	29
Hypermethylation of the ALOX12 and CBS promoters in osteoporosis: Potential biomarkers for early diagnosis	29
New insights into the cardio-renal benefits of SGLT2 inhibitors and the coordinated role of miR-30 family	29
Reduction of Atp5b protects mice from diet-induced obesity	29
Inhibition of VEGFR2 overcomes venetoclax-resistance in diffuse large B-cell lymphoma cells	28
The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP+ ratio	28
Actin polymerization regulates the osteogenesis of hASCs by influencing α-tubulin expression and Eg5 activity	28
SPINOPHILIN: A multiplayer tumor suppressor	28
Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways	28
The 21-base pair deletion mutant Calpain3 does not inhibit wild-type Calpain3 activity	28
Publisher’s Note	27
Pseudotyped lentiviral vectors: Ready for translation into targeted cancer gene therapy?	27
3′-UTR of the SARS-CoV-2 genome as a possible source of piRNAs	27

Hallmark guided identification and characterization of a novel immune-relevant signature for prognostication of recurrence in stage I–III lung adenocarcinoma	27
Emerging role of SETD2 in the development and function of immune cells	27
The paradoxical functions of long noncoding RNAs in hepatocellular carcinoma: Implications in therapeutic opportunities and precision medicine	27
Hsa_circ_0007099 and PIP4K2A coexpressed in diffuse large B-cell lymphoma with clinical significance	27
MPDZ variants associated with epilepsies and/or febrile seizures and the individualized genotype-phenotype correlation	26
MiR-743a-5p regulates differentiation of myoblast by targeting Mob1b in skeletal muscle development and regeneration	26
Vault RNAs (vtRNAs): Rediscovered non-coding RNAs with diverse physiological and pathological activities	25
Restriction of YWHAB-mediated YAP cytoplasmic retention is a novel mechanism underlying stemness maintenance and chemoresistance in ovarian cancer peritoneal metastasis	25
Targeting SAMHD1: To overcome multiple anti-cancer drugs resistance in hematological malignancies	25
The genomic and epigenomic landscape of iridocorneal endothelial syndrome	25
Autophagic dysfunction of β cell dysfunction in type 2 diabetes, a double-edged sword	25
CMTM3 suppresses bone formation and osteogenic differentiation of mesenchymal stem cells through inhibiting Erk1/2 and RUNX2 pathways	24
Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance	24
Targeting PD-1/PD-L1 in cancer immunotherapy: An effective strategy for treatment of triple-negative breast cancer (TNBC) patients	23
Circulating fibroblasts present neutrophil-like features in severe COVID-19 cases revealed by single-cell landscape analyses	23
New insights into the suppression of inflammation and lipid accumulation by JAZF1	22
The germline genetics of mild-to-moderate penetrance: An intriguing role of PRAME in multiple carcinogenesis	22
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth	22
Abatacept is effective in Chinese patients with LRBA and CTLA4 deficiency	22
Coinheritance of germline mutations in APC and MUTYH genes defines the clinical outcome of adenomatous polyposis syndromes	22
Characterization of the molecular dysfunctions occurring in Aicardi-Goutières syndrome patients with mutations in ADAR1	22
Hydrogen sulfide-induced post-translational modification as a potential drug target	22
Transcriptomic analysis identifies a pan-cancer association of IL27 expression with cancer prognosis and immune microenvironment	22
AUTS2 expression within mammalian lineage: A predictor of neural networks involved in autism spectrum disorders	21
ScMicrobesAtlas: A comprehensive microbial atlas at single-cell resolution in human disease contexts	21
Increased N6-methyladenosine is related to the promotion of the methyltransferase METTL14 in ovarian aging	21
Epigenetic regulation of SARS-Cov-2 spike protein modulates cellular viability and nascent RNA transcription in neuronal cells	21
Single-cell spatial transcriptomics in cardiovascular development, disease, and medicine	20
Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration	20
Targeting glutamine metabolism enhances responses to platinum-based chemotherapy in triple-negative breast cancers (TNBC)	20
Low expression of OXCT1 promote colorectal cancer liver metastasis by upregulating CDK8 and β-catenin via H3 acetylation	20
Reduced neutralization of SARS-CoV-2 B.1.617 variant by convalescent and vaccinated sera	20
Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children	20
Nucleolin promotes tumor growth in colorectal cancer by enhancing hnRNPA1-mediated PKM2 alternative splicing	20
Regulation mechanism and pathogenic role of lncRNA plasmacytoma variant translocation 1 (PVT1) in human diseases	20
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4	20
A novel homozygous missense variant in ARSK causes MPS X, a new subtype of mucopolysaccharidosis	20
Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy	20
Deletion of heterogeneous nuclear ribonucleoprotein K in satellite cells leads to inhibited skeletal muscle regeneration in mice	20
Recent advances of mechanosensitive genes in vascular endothelial cells for the formation and treatment of atherosclerosis	20
Co-alteration of Myc and RTK-RAS pathways defines a liver-metastatic propensity and immune-cold subgroup of pancreatic adenocarcinoma	19
The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases	19
Covalent inhibitor targets KRasG12C: A new paradigm for drugging the undruggable and challenges ahead	19
The generation and use of animal models of osteosarcoma in cancer research	19
Nidogen: A matrix protein with potential roles in musculoskeletal tissue regeneration	19
CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma	19
Downregulation of nc886 contributes to prostate cancer cell invasion and TGFβ1-induced EMT	19
The role of regulators of RNA m6A methylation in lung cancer	18
RETRACTED: Corrigendum to “Lipopolysaccharide-induced podocyte injury is regulated by calcineurin/NFAT and TLR4/MyD88/NF-κB signaling pathways through Angiopoietin-like protein 4” [Genes Dis DOI: 10.1	18
Construction of a novel six-gene signature to predict tumour response to induction chemotherapy and overall survival in locoregionally advanced laryngeal and hypopharyngeal carcinoma	18
Elevation of TRIM44 potentiates propagation of gastric cancer stem cells	18
Neurokinin-2 receptor antagonist SR48968 induced necroptosis of myeloid leukemia cells by calcium overload-driven reactive oxygen species accumulation	18
Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways	18
The impact of broad glutamine metabolism inhibition on the tumor microenvironment	18
Ultra-conserved non-coding sequences within the FOXF1 enhancer are critical for human lung development	18
PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma	18
Liver HMGCS2 is critical in the maintenance of liver lipid homeostasis during fasting	18
Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression	17
Corrigendum to “Cellular senescence-driven transcriptional reprogramming of the MAFB/NOTCH3 axis activates the PI3K/AKT pathway and promotes osteosarcoma progression” [Genes & Diseases 11 (2024) 9	17
The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers	17
A lncRNA MEG3 variant enhances telomerase activity by increasing DNA damage repair ability in human liver cancer stem cells	17
Assessment of the transcriptomic consequences and MAU2 protein levels in edited induced pluripotent stem cells with NIPBL pathogenic variants	17
The role of m6A RNA methylation in autoimmune diseases: Novel therapeutic opportunities	17
Mutations in GTPBP3 cause aberrant mitochondrial respiration associated with combined oxidative phosphorylation deficiency 23	17
A novel BCAT1 inhibitor bufalin sensitizes pancreatic cancer cells to chemotherapy	17
In vivo production of CAR T cell: Opportunities and challenges	17
Development of a dual targeting scaffold of SET7/MLL inhibitor for castration-resistant prostate cancer treatment	16
Osteoarthritis versus psoriasis arthritis: Physiopathology, cellular signaling, and therapeutic strategies	16
PIWI-interacting RNAs: Mitochondria-based biogenesis and functions in cancer	16
Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells	16
Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia	16
Genetic and immunologic characteristics of colorectal cancer patients with KRAS mutations and predictive significance of tumor immune microenvironment in adjuvant chemotherapy	16
The key mediator of diabetic kidney disease: Potassium channel dysfunction	16
MMP-9 deficiency accelerates the progress of periodontitis	15
Identification of TP53 mutation-associated prognostic genes and investigation of the immune cell infiltration in patients with hepatocellular carcinoma	15
Single-cell RNA sequencing in juvenile idiopathic arthritis	15
Identification of immune cell infiltration pattern in diabetic nephropathy	15
Cardiac regeneration: Pre-existing cardiomyocyte as the hub of novel signaling pathway	15
Genetic association analysis-based networks and classification of human UCP1 polymorphisms	15
Alterations in expression and localization of POMGNT1 in the APP/PS1 mouse model of Alzheimer's disease	15

The crosstalk between non-coding RNAs and oxidative stress in cancer progression	15
PDK1 promotes breast cancer progression by enhancing the stability and transcriptional activity of HIF-1α	15
TMEM132E ablation suppresses tumor progression and restores tamoxifen sensitivity by inducing ERα expression in triple-negative breast cancer	15
Circulating and non-circulating proteins and nucleic acids as biomarkers and therapeutic molecules in ovarian cancer	15
Immune characteristics analysis reveals two key inflammatory factors correlated to the expressions of SARS-CoV-2 S1-specific antibodies	15
lncRNA POU3F3 promotes osteosarcoma progression through GPX4-modulated ferroptosis by interaction with IGF2BP2 to facilitate NRF2 mRNA stability	15
Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin	15
Biallelic inactivation of SDHA results in comorbidity of pediatric recurrent neuroblastoma and gastric stromal tumor	15
GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus	15
Profiling of histone H3 trimethylation and distinct epigenetic pattern of chromosome Y in the transformed bronchial epithelial cells induced by consecutive arsenic treatment	15
XBP1 splicing contributes to endoplasmic reticulum stress-induced human islet amyloid polypeptide up-regulation	14
The landscape of UBE2S in hepatocellular carcinoma: Prognostic significance, immuno-oncology feature and drug response	14
Prognosis prediction and immune microenvironment features of breast cancer indicated by a cuproptosis-associated long non-coding RNA signature	14
Novel virulence-related genes that contribute to clinical infections of Salmonella enteritidis	14
Krüppel-like factor 10 (KLF10) as a critical signaling mediator: Versatile functions in physiological and pathophysiological processes	14
Predictive value of T cell receptor repertoire profiling for immunosuppressive therapy in severe aplastic anemia	14
Hematological and neurological expressed 1-mediated anoikis resistance promotes anaplastic thyroid cancer metastasis	14
Single-cell RNA sequencing reveals tumor microenvironment characteristics in ovarian malignant Brenner tumor	14
Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer	14
Identification of TMEM217 as a novel prognostic biomarker and potential therapeutic target in acute myeloid leukemia	14
Friend or foe for obesity: How hepatokines remodel adipose tissues and translational perspective	14
Tumor suppressor p53 cross-talks with TRIM family proteins	14
Exosomal long non-coding RNAs: Emerging players in cancer metastasis and potential diagnostic biomarkers for personalized oncology	13
High glucose promotes macrophage M1 polarization through miR-32/Mef2d/cAMP signaling pathway	13
Melanoma: Molecular genetics, metastasis, targeted therapies, immunotherapies, and therapeutic resistance	13
Calcineurin in development and disease	13
Myelin protein zero (P0)- and Wnt1-Cre marked muscle resident neural crest-derived mesenchymal progenitor cells give rise to heterotopic ossification in mouse models	13
OTX1 promotes TNBC cell proliferation and tumor growth through the ERK pathway	13
Establishment of a mouse model of respiratory mycoplasma challenged intranasally combined intraperitoneally eliciting chronic inflammation and lung consolidation	13
Targeting CD47-SIRPα axis for Hodgkin and non-Hodgkin lymphoma immunotherapy	13
The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases	13
DEAD-box RNA helicases with special reference to p68: Unwinding their biology, versatility, and therapeutic opportunity in cancer	13
Deregulated miRNA clusters in ovarian cancer: Imperative implications in personalized medicine	13
COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery	13
BET bromodomain inhibitor JQ1 regulates spermatid development by changing chromatin conformation in mouse spermatogenesis	13
A novel FGFR1 inhibitor CYY292 suppresses tumor progression, invasion, and metastasis of glioblastoma by inhibiting the Akt/GSK3β/snail signaling axis	13
Studies on the fat mass and obesity-associated (FTO) gene and its impact on obesity-associated diseases	13
The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4	13
Multi-omics integration reveals potential stage-specific druggable targets in T-cell acute lymphoblastic leukemia	12
Decoding the impact of gut microbiota on heart failure	12
Correspondence (reply): The application conditions of false discovery rate control	12
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]	12
MyD88 in macrophages protects against colitis via inhibiting the activation of NLRP3 inflammasome in epithelial cells	12
Post-transcriptional regulation of DEAD-box RNA helicases in hematopoietic malignancies	12
Cyclin G2, a novel target of sulindac to inhibit cell cycle progression in colorectal cancer	12
Long noncoding RNA (lncRNA) HOTAIR: Pathogenic roles and therapeutic opportunities in gastric cancer	12
mTOR pathway: A key player in diabetic nephropathy progression and therapeutic targets	12
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism	12
Performance analysis of markers for prostate cell typing in single-cell data	12
Role of lncRNA MALAT1 in UVA-induced corneal endothelial senescence	12
Insights into the role of RNA m6A modification in the metabolic process and related diseases	12
Phase I trial of human umbilical cord-derived mesenchymal stem cells for treatment of severe bronchopulmonary dysplasia	12
EBV-Mir-BART5-5p targets p53 independent pathway in cytoplasm: Potential role in EBV lymphomagenesis	12
Targeting LIF/LIFR signaling in cancer	12
Advances in single-cell sequencing technology in microbiome research	12
The role of lncRNAs in AKI and CKD: Molecular mechanisms, biomarkers, and potential therapeutic targets	12
The landscape of epigenetic regulation and therapeutic application of N6-methyladenosine modifications in non-coding RNAs	12
Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling	12
Akt3 promotes cancer stemness in triple-negative breast cancer through YB1-Snail/Slug signaling axis	12
ADAM8 inactivation modulates cellular component assembly gene expression in the mouse intervertebral disc	12
BAF45D regulates spinal cord neural stem/progenitor cell fate through the SMAD-PAX6 axis	12
Identification of cross-reactive CD8+ T cell receptors with high functional avidity to a SARS-CoV-2 immunodominant epitope and its natural mutant variants	12
SFRP5 inhibits melanin synthesis of melanocytes in vitiligo by suppressing the Wnt/β-catenin signaling	12
Simple gene knockout by single gene-directed multiplex CRISPR-Cpf1	11
TMEM249-mediated sperm hyperactivation is required for mouse fertility	11
Promising prognostic value of ATP binding cassette transporters and their correlation with tumor-infiltrating immune cells in lung adenocarcinoma	11
Inflammation and cancer: paradoxical roles in tumorigenesis and implications in immunotherapies	11
Epigenetic regulation of mesenchymal stem cell aging through histone modifications	11
Defective EMC1 drives abnormal retinal angiogenesis via Wnt/β-catenin signaling and may be associated with the pathogenesis of familial exudative vitreoretinopathy	11
miR-106b as an emerging therapeutic target in cancer	11
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics	11
A prognostic model of patients with pancreatic cancer based on four N6-methyladenosine-related lncRNAs and analysis of related immune infiltration	11
Welander distal myopathy-associated TIA1 mutation exacerbates P-body and stress granule dynamics concomitant with nucleolar stress under oxidative stress	11
Cardiomyocyte proliferation: Advances and insights in macrophage-targeted therapy for myocardial injury	10
Otof gene transfer in DFNB9 mice carrying human founder non-truncating alleles	10
Recent advances in methylation modifications of microRNA	10
Defective claudin-10 causes a novel variation of HELIX syndrome through compromised tight junction strand assembly	10
A novel method for the detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo	10
CircDONSON regulates the proliferation, invasion and migration of non-small cell lung cancer cells through the MAPK signaling pathway	10
A complex signature network that controls the upregulation of PRMT5 in colorectal cancer	10
De novo lipogenesis prolongs the lifespan and supports the immunosuppressive phenotype of neutrophils in HCC metastasis	10
Guarding against digestive-system cancers: Unveiling the role of Chk2 as a potential therapeutic target	10
PDLIM1 sustains DNA damage response by promoting chromatin relaxation and activating DNA–PK complex	10
Targeted nanopore sequencing for the identification of novel PRMT1 circRNAs unveils a diverse transcriptional profile of this gene in breast cancer cells	10
The Janus-faced role of Piezo1 in cardiovascular health under mechanical stimulation	10
Key roles of ubiquitination in regulating critical regulators of cancer stem cell functionality	10
LncRNA MIR31HG controls the proliferation and metastasis of gastric cancer by c-CBL-mediated degradation of β-catenin	10
Mitochondrial SLC3A1 regulates sexual dimorphism in cystinuria	10
Corrigendum to “Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference” [ 5(2018):172–18	10
Biallelic mutations in UGDH cause congenital microcephaly	10
Tumor microenvironment of cancer stem cells: Perspectives on cancer stem cell targeting	10
m6A levels and expression of its modification genes show significant differences in breast cancer molecular subtypes	9
A new and more informative subtyping scheme for breast cancer based on co-expression of metabolic genes	9
Irisin regulates pancreatic lipases through PPARγ-PGCα-FNDC5 pathway	9
Mitochondria-derived small RNAs as diagnostic biomarkers in lung cancer patients through a novel ratio-based expression analysis methodology	9