Genes & Diseases

Papers
(The H4-Index of Genes & Diseases is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics332
The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases266
Age-related macular degeneration: Epidemiology, genetics, pathophysiology, diagnosis, and targeted therapy147
CCL5/CCR5 axis in human diseases and related treatments139
Development of cell-based pseudovirus entry assay to identify potential viral entry inhibitors and neutralizing antibodies against SARS-CoV-282
Critical roles of FTO-mediated mRNA m6A demethylation in regulating adipogenesis and lipid metabolism: Implications in lipid metabolic disorders82
Molecular subtypes of colorectal cancer: An emerging therapeutic opportunity for personalized medicine79
NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation77
The functions of N6-methyladenosine modification in lncRNAs71
Regulation of ferroptosis in cancer cells by YAP/TAZ and Hippo pathways: The therapeutic implications68
Alternative polyadenylation of mRNA and its role in cancer66
Gastrointestinal symptoms, pathophysiology, and treatment in COVID-1964
Oridonin and its derivatives for cancer treatment and overcoming therapeutic resistance63
The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases62
Breast and gut microbiome in health and cancer55
Ferroptosis: An emerging therapeutic opportunity for cancer53
Targeting RAS–RAF–MEK–ERK signaling pathway in human cancer: Current status in clinical trials52
The clinical and immunological features of pediatric COVID-19 patients in China51
Genomics functional analysis and drug screening of SARS-CoV-249
Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome47
Targeting LIF/LIFR signaling in cancer44
ITGA2 promotes expression of ACLY and CCND1 in enhancing breast cancer stemness and metastasis44
The biogenesis and secretion of exosomes and multivesicular bodies (MVBs): Intercellular shuttles and implications in human diseases43
Cancer: An unknown territory; rethinking before going ahead42
Wnt signaling: Essential roles in osteoblast differentiation, bone metabolism and therapeutic implications for bone and skeletal disorders41
Obesity as potential breast cancer risk factor for postmenopausal women41
Emerging roles of activating transcription factor (ATF) family members in tumourigenesis and immunity: Implications in cancer immunotherapy39
Emerging important roles of circRNAs in human cancer and other diseases38
Notch signaling: Its essential roles in bone and craniofacial development37
Tumor suppressor p53 cross-talks with TRIM family proteins37
Characteristics and regulation of mesenchymal stem cell plasticity by the microenvironment — specific factors involved in the regulation of MSC plasticity37
The mitophagy receptor FUN14 domain-containing 1 (FUNDC1): A promising biomarker and potential therapeutic target of human diseases36
Inflammation and cancer: paradoxical roles in tumorigenesis and implications in immunotherapies36
Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics36
The Hippo Tumor Suppressor Pathway (YAP/TAZ/TEAD/MST/LATS) and EGFR-RAS-RAF-MEK in cancer metastasis36
Mitochondrial dysfunction: A hidden trigger of autism?36
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