Neurobiology of Stress

Article	Citations
Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice	150
Gender-related time course of sleep disturbances and psychological symptoms during the COVID-19 lockdown: A longitudinal study on the Italian population	98
A predictable home environment may protect child mental health during the COVID-19 pandemic	92
Allopregnanolone in postpartum depression: Role in pathophysiology and treatment	70
A systematic review of the Trier Social Stress Test methodology: Issues in promoting study comparison and replicable research	70
Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle	70
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota	60
Synaptic and behavioral effects of chronic stress are linked to dynamic and sex-specific changes in microglia function and astrocyte dystrophy	50
Allopregnanolone: From molecular pathophysiology to therapeutics. A historical perspective	50
Alterations of frontal-temporal gray matter volume associate with clinical measures of older adults with COVID-19	45
Post-finasteride syndrome: An emerging clinical problem	42
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice	42
Social isolation alters behavior, the gut-immune-brain axis, and neurochemical circuits in male and female prairie voles	39
Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor	37
Involvement of oxidative stress and mitochondrial mechanisms in air pollution-related neurobiological impairments	34
Pleiotropic actions of allopregnanolone underlie therapeutic benefits in stress-related disease	34
Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior	32
Amygdala functional connectivity in the acute aftermath of trauma prospectively predicts severity of posttraumatic stress symptoms	31
Stress hormones mediate developmental plasticity in vertebrates with complex life cycles	30
To stress or not to stress: Brain-behavior-immune interaction may weaken or promote the immune response to SARS-CoV-2	30
Exposure to different early-life stress experiences results in differentially altered DNA methylation in the brain and immune system	30
Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality	29
The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure	28
The role of allopregnanolone in depressive-like behaviors: Focus on neurotrophic proteins	28
Susceptibility and resilience to chronic social defeat stress in adolescent male mice: No correlation between social avoidance and sucrose preference	27

Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical tria	27
Lateral hypothalamus orexinergic inputs to lateral habenula modulate maladaptation after social defeat stress	27
Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham controlled trial	27
Mediterranean diet, stress resilience, and aging in nonhuman primates	26
Glucocorticoids, the evolution of the stress-response, and the primate predicament	26
Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review	25
A novel mouse model for vulnerability to alcohol dependence induced by early-life adversity	24
Mineralocorticoid receptor and glucocorticoid receptor work alone and together in cell-type-specific manner: Implications for resilience prediction and targeted therapy	24
Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression	24
Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula	24
Deconstructing the role of the exposome in youth suicidal ideation: Trauma, neighborhood environment, developmental and gender effects	24
Prenatal stress leads to deficits in brain development, mood related behaviors and gut microbiota in offspring	23
Pregnane steroidogenesis is altered by HIV-1 Tat and morphine: Physiological allopregnanolone is protective against neurotoxic and psychomotor effects	22
Chronic adolescent stress causes sustained impairment of cognitive flexibility and hippocampal synaptic strength in female rats	22
Early life adversity predicts brain-gut alterations associated with increased stress and mood	22
Early life stress-induced alterations in the activity and morphology of ventral tegmental area neurons in female rats	21
Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia	21
Cellular senescence as a driver of cognitive decline triggered by chronic unpredictable stress	21
The neural correlates of psychosocial stress: A systematic review and meta-analysis of spectral analysis EEG studies	21
Associations between PTSD-Related extinction retention deficits in women and plasma steroids that modulate brain GABAA and NMDA receptor activity	21
Forecasting individual risk for long-term Posttraumatic Stress Disorder in emergency medical settings using biomedical data: A machine learning multicenter cohort study	21
Composite contributions of cerebrospinal fluid GABAergic neurosteroids, neuropeptide Y and interleukin-6 to PTSD symptom severity in men with PTSD	20
Prospective association of maternal psychosocial stress in pregnancy with newborn hippocampal volume and implications for infant social-emotional development	20
Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress	19
Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress	19
Pregnancy associated epigenetic markers of inflammation predict depression and anxiety symptoms in response to discrimination	19
Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring's brain and behavior	19
Cholinergic neurotransmission in the basolateral amygdala during cued fear extinction	18
Dissection of the relationship between anxiety and stereotyped self-grooming using the Shank3B mutant autistic model, acute stress model and chronic pain model	18
Post-traumatic stress disorder and its association with stroke and stroke risk factors: A literature review	18
Variations in response to trauma and hippocampal subfield changes	18
BNST transient activity associates with approach behavior in a stressful environment and is modulated by the parabrachial nucleus	18
Long-term effects of stress early in life on microRNA-30a and its network: Preventive effects of lurasidone and potential implications for depression vulnerability	18
Early life adversity in male mice sculpts reward circuits	18
Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD	18
Understanding how stress responses and stress-related behaviors have evolved in zebrafish and mammals	17
A projection from the paraventricular nucleus of the thalamus to the shell of the nucleus accumbens contributes to footshock stress-induced social avoidance	17
Dynamic functional network connectivity associated with post-traumatic stress symptoms in COVID-19 survivors	17
miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine	17
Stress induces microglia-associated synaptic circuit alterations in the dorsomedial prefrontal cortex	17
Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli	17
The functional connectome predicts feeling of stress on regular days and during the COVID-19 pandemic	17
Cannabis vapor self-administration elicits sex- and dose-specific alterations in stress reactivity in rats	16
Proteomic and mitochondrial adaptations to early-life stress are distinct in juveniles and adults	16
Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice	16
PPAR and functional foods: Rationale for natural neurosteroid-based interventions for postpartum depression	16
Resilience or susceptibility to traumatic stress: Potential influence of the microbiome	16
Genetic evidence for a large overlap and potential bidirectional causal effects between resilience and well-being	16
Acute sleep deprivation during pregnancy in rats: Rapid elevation of placental and fetal inflammation and kynurenic acid	16
Brain-wide mapping of c-fos expression in the single prolonged stress model and the effects of pretreatment with ACH-000029 or prazosin	15

What the hippocampus tells the HPA axis: Hippocampal output attenuates acute stress responses via disynaptic inhibition of CRF+ PVN neurons	15
Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress	15
Allopregnanolone (1938–2019): A trajectory of 80 years of outstanding scientific achievements	15
Fluoxetine and environmental enrichment similarly reverse chronic social stress-related depression- and anxiety-like behavior, but have differential effects on amygdala gene expression	15
Epigenetic mechanisms impacted by chronic stress across the rodent lifespan	15
Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models	15
Juvenile exposure to acute traumatic stress leads to long-lasting alterations in grey matter myelination in adult female but not male rats	14
Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue	14
The stress susceptibility factor FKBP51 controls S-ketamine-evoked release of mBDNF in the prefrontal cortex of mice	14
Dopamine modulates individual differences in avoidance behavior: A pharmacological, immunohistochemical, neurochemical and volumetric investigation	14
Erasing m6A-dependent transcription signature of stress-sensitive genes triggers antidepressant actions	14
Telencephalic regulation of the HPA axis in birds	14
Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy	14
Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors	14
The functional connectome in posttraumatic stress disorder	14
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats	13
Stress enhances hippocampal neuronal synchrony and alters ripple-spike interaction	13
Chronic restraint stress produces sex-specific behavioral and molecular outcomes in the dorsal and ventral rat hippocampus	13
Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration	13
Changes in the rodent gut microbiome following chronic restraint stress and low-intensity rTMS	13
Sex and age differences in cognitive bias and neural activation in response to cognitive bias testing	13
Sex differences in the delayed impact of acute stress on the amygdala	13
Dual imaging of dendritic spines and mitochondria in vivo reveals hotspots of plasticity and metabolic adaptation to stress	13
Neural impact of neighborhood socioeconomic disadvantage in traumatically injured adults	13
Prevalence of posttraumatic stress symptoms in health care workers after exposure to patients with COVID-19	13
The cerebellum and psychological trauma: A systematic review of neuroimaging studies	13
Connecting the biology of stress, allostatic load and epigenetics to social structures and processes	13
From genetics to systems biology of stress-related mental disorders	13
miR-34a induces spine damages via inhibiting synaptotagmin-1 in depression	13
Programming effects of peripubertal stress on spatial learning	13
Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats	12
Intersectional analysis of chronic mild stress-induced lncRNA-mRNA interaction networks in rat hippocampus reveals potential anti-depression/anxiety drug targets	12
Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits	12
“Live together, die alone”: The effect of re-socialization on behavioural performance and social-affective brain-related proteins after a long-term chronic social isolation stress	12
Stress-induced visceral pain in female rats is associated with epigenetic remodeling in the central nucleus of the amygdala	12
Individual baseline behavioral traits predict the resilience phenotype after chronic social defeat	12
Interactions between pyridostigmine bromide and stress on glutamatergic neurochemistry: Insights from a rat model of Gulf War Illness	12
miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF	12
The social instability stress paradigm in rat and mouse: A systematic review of protocols, limitations, and recommendations	11
GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?	11
Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats	11
Reversed patterns of resting state functional connectivity for females vs. males in posttraumatic stress disorder	11
Stress-induced cortisol response is associated with right amygdala volume in early childhood	11
Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice	11
Hormonal contraceptive phases matter: Resting-state functional connectivity of emotion-processing regions under stress	11
Molecular impacts of childhood abuse on the human brain	11
Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders	11
Deficits across multiple behavioral domains align with susceptibility to stress in 129S1/SvImJ mice	11
Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus	11
Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents	11
Childhood maltreatment results in altered deactivation of reward processing circuits in depressed patients: A functional magnetic resonance imaging study of a facial emotion recognition task	11
Effects of chronic social stress on oligodendrocyte proliferation-maturation and myelin status in prefrontal cortex and amygdala in adult mice	11
LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse	10
Restoring tripartite glutamatergic synapses: A potential therapy for mood and cognitive deficits in Gulf War illness	10
Stress-induced changes in modular organizations of human brain functional networks	10
Dyslexia as an adaptation to cortico-limbic stress system reactivity	10
Regulation of stress-provoked aggressive behavior using endocannabinoids	10
Male long-Evans rats: An outbred model of marked hypothalamic-pituitary-adrenal hyperactivity	10
Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy	10
Blunted neural and psychological stress processing predicts future grey matter atrophy in multiple sclerosis	10
Immune system regulation and role of the human leukocyte antigen in posttraumatic stress disorder	10
Dissociable roles of the nucleus accumbens core and shell subregions in the expression and extinction of conditioned fear	10
The role of TET proteins in stress-induced neuroepigenetic and behavioural adaptations	10
Altered stress responses in adults born by Caesarean section	10
Social support modulates the association between PTSD diagnosis and medial frontal volume in Chinese adults who lost their only child	10
Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice	9
Translational relevance of behavioral, neural, and electroencephalographic profiles in a mouse model of post-traumatic stress disorder	9
Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence	9
Insights from a laboratory and naturalistic investigation on stress, rumination and frontal brain functioning in MDD: An fNIRS study	9
A sex-dependent delayed maturation of visual plasticity induced by adverse experiences in early childhood	9
Forebrain overexpression of type 1 adenylyl cyclase promotes molecular stability and behavioral resilience to physical stress	9
A prospective examination of sex differences in posttraumatic autonomic functioning	9
Multidimensional predictors of antidepressant responses: Integrating mitochondrial, genetic, metabolic and environmental factors with clinical outcomes	9
Functional networks activated by controllable and uncontrollable stress in male and female rats	9
The influence of sleep on fear extinction in trauma-related disorders	9
Bacteria - derived short chain fatty acids restore sympathoadrenal responsiveness to hypoglycemia after antibiotic-induced gut microbiota depletion	9
‘Doctor, I am so stressed out!’ A descriptive study of biological, psychological, and socioemotional markers of stress in individuals who self-identify as being ‘very stressed out’ or ‘zen’	9
The coupling of RACK1 with the beta isoform of the glucocorticoid receptor promotes resilience to chronic stress exposure	9
Ethanol intake in male mice exposed to social defeat: Environmental enrichment potentiates resilience	9
Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons	9

Stress during puberty exerts sex-specific effects on depressive-like behavior and monoamine neurotransmitters in adolescence and adulthood	8
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD	8
A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders	8
Threat imminence reveals links among unfolding of anticipatory physiological response, cortical-subcortical intrinsic functional connectivity, and anxiety	8
Transcriptomics of the depressed and PTSD brain	8
Neural connectome prospectively encodes the risk of post-traumatic stress disorder (PTSD) symptom during the COVID-19 pandemic	8
Reactivating a positive feedback loop VTA-BLA-NAc circuit associated with positive experience ameliorates the attenuated reward sensitivity induced by chronic stress	8
Stronger functional network connectivity and social support buffer against negative affect during the COVID-19 outbreak and after the pandemic peak	8
Prebiotic supplementation modulates selective effects of stress on behavior and brain metabolome in aged mice	8
Adult food choices depend on sex and exposure to early-life stress: Underlying brain circuitry, adipose tissue adaptations and metabolic responses	8
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats	8
Amygdala size varies with stress perception	8
Longitudinal CSF proteome profiling in mice to uncover the acute and sustained mechanisms of action of rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK)	8
Stress induces divergent gene expression among lateral habenula efferent pathways	7
Neurobiological effects of phospholipids in vitro: Relevance to stress-related disorders	7
Sex differences in the association between basal serum cortisol concentrations and cortical thickness	7
Riluzole prevents stress-induced spine plasticity in the hippocampus but mimics it in the amygdala	7
Impact of stress resilience and susceptibility on fear learning, anxiety, and alcohol intake	7
Specific sub-regions along the longitudinal axis of the hippocampus mediate antidepressant-like behavioral effects	7
Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (Nav) channels properties	7
The effects of stress across the lifespan on the brain, cognition and mental health: A UK biobank study	7
Dissociable impact of childhood trauma and deployment trauma on affective modulation of startle	7
Corticosterone dynamically regulates retrotransposable element expression in the rat hippocampus and C6 cells	7
Consideration of sex as a biological variable in the translation of pharmacotherapy for stress-associated drug seeking	7
Differences in gut microbiota associated with stress resilience and susceptibility to single prolonged stress in female rodents	7
Microglia-specific transcriptional repression of interferon-regulated genes after prolonged stress in mice	7
Longitudinal monitoring of prefrontal cortical ensemble dynamics reveals new insights into stress habituation	7
The habenula clock influences response to a stressor	6
Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice	6
Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans	6
Choosing memory retrieval strategies: A critical role for inhibition in the dentate gyrus	6
Validation of an Electrochemical Sensor to Detect Cortisol Responses to the Trier Social Stress Test	6
In vitro modeling of the neurobiological effects of glucocorticoids: A review	6
The role of the stress system in recovery after traumatic brain injury: A tribute to Bruce S. McEwen	6
Impact of stress on inhibitory neuronal circuits, our tribute to Bruce McEwen	6
Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice	6
The stress of losing sleep: Sex-specific neurobiological outcomes	6
Resource scarcity but not maternal separation provokes unpredictable maternal care sequences in mice and both upregulate Crh-associated gene expression in the amygdala	6
Optogenetically-induced long term depression in the rat orbitofrontal cortex ameliorates stress-induced reversal learning impairment	6
Maternal adverse childhood experiences and infant subcortical brain volume	6
Stress enhances emotional memory-related theta oscillations in the medial temporal lobe	6
Brain activity during a post-stress working memory task differs between the hormone-present and hormone-absent phase of hormonal contraception	6
Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice	6
Inhibition of adult neurogenesis reduces avoidance behavior in male, but not female, mice subjected to early life adversity	6
Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons	6
Genomic regulation of Krüppel-like-factor family members by corticosteroid receptors in the rat brain	6
Remembering and forgetting in sleep: Selective synaptic plasticity during sleep driven by scaling factors Homer1a and Arc	6