Neurobiology of Stress

Article	Citations
A predictable home environment may protect child mental health during the COVID-19 pandemic	109
Gender-related time course of sleep disturbances and psychological symptoms during the COVID-19 lockdown: A longitudinal study on the Italian population	102
A systematic review of the Trier Social Stress Test methodology: Issues in promoting study comparison and replicable research	77
Probiotic consumption relieved human stress and anxiety symptoms possibly via modulating the neuroactive potential of the gut microbiota	74
Synaptic and behavioral effects of chronic stress are linked to dynamic and sex-specific changes in microglia function and astrocyte dystrophy	57
Alterations of frontal-temporal gray matter volume associate with clinical measures of older adults with COVID-19	55
A novel arousal-based individual screening reveals susceptibility and resilience to PTSD-like phenotypes in mice	48
Social isolation alters behavior, the gut-immune-brain axis, and neurochemical circuits in male and female prairie voles	47
Stress hormones mediate developmental plasticity in vertebrates with complex life cycles	42
Anatomically and functionally distinct locus coeruleus efferents mediate opposing effects on anxiety-like behavior	41
The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure	40
The neural correlates of psychosocial stress: A systematic review and meta-analysis of spectral analysis EEG studies	37
Parvalbumin interneuron alterations in stress-related mood disorders: A systematic review	36
Glucocorticoids, the evolution of the stress-response, and the primate predicament	35
Sex-stratified gene-by-environment genome-wide interaction study of trauma, posttraumatic-stress, and suicidality	35
Lateral hypothalamus orexinergic inputs to lateral habenula modulate maladaptation after social defeat stress	35
To stress or not to stress: Brain-behavior-immune interaction may weaken or promote the immune response to SARS-CoV-2	34
Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula	33
Exposure to different early-life stress experiences results in differentially altered DNA methylation in the brain and immune system	33
Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham controlled trial	32
A novel mouse model for vulnerability to alcohol dependence induced by early-life adversity	31
Deconstructing the role of the exposome in youth suicidal ideation: Trauma, neighborhood environment, developmental and gender effects	30
Forecasting individual risk for long-term Posttraumatic Stress Disorder in emergency medical settings using biomedical data: A machine learning multicenter cohort study	30
Early life adversity predicts brain-gut alterations associated with increased stress and mood	29
Prospective association of maternal psychosocial stress in pregnancy with newborn hippocampal volume and implications for infant social-emotional development	29

Understanding how stress responses and stress-related behaviors have evolved in zebrafish and mammals	29
Chronic adolescent stress causes sustained impairment of cognitive flexibility and hippocampal synaptic strength in female rats	29
Mediterranean diet, stress resilience, and aging in nonhuman primates	29
Mineralocorticoid receptor and glucocorticoid receptor work alone and together in cell-type-specific manner: Implications for resilience prediction and targeted therapy	29
Lacticaseibacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical tria	28
Increased methylation of NR3C1 and SLC6A4 is associated with blunted cortisol reactivity to stress in major depression	27
Prenatal stress leads to deficits in brain development, mood related behaviors and gut microbiota in offspring	27
Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia	26
Cholinergic neurotransmission in the basolateral amygdala during cued fear extinction	25
Dissection of the relationship between anxiety and stereotyped self-grooming using the Shank3B mutant autistic model, acute stress model and chronic pain model	25
miR-9-5p is involved in the rescue of stress-dependent dendritic shortening of hippocampal pyramidal neurons induced by acute antidepressant treatment with ketamine	24
Cellular senescence as a driver of cognitive decline triggered by chronic unpredictable stress	24
Characterizing the behavioral and neuroendocrine features of susceptibility and resilience to social stress	24
Dynamic functional network connectivity associated with post-traumatic stress symptoms in COVID-19 survivors	24
Early life stress-induced alterations in the activity and morphology of ventral tegmental area neurons in female rats	24
Associations between PTSD-Related extinction retention deficits in women and plasma steroids that modulate brain GABAA and NMDA receptor activity	23
What the hippocampus tells the HPA axis: Hippocampal output attenuates acute stress responses via disynaptic inhibition of CRF+ PVN neurons	23
Long-term effects of stress early in life on microRNA-30a and its network: Preventive effects of lurasidone and potential implications for depression vulnerability	22
Pregnancy associated epigenetic markers of inflammation predict depression and anxiety symptoms in response to discrimination	22
Maternal antioxidant treatment prevents the adverse effects of prenatal stress on the offspring's brain and behavior	22
Post-traumatic stress disorder and its association with stroke and stroke risk factors: A literature review	22
Stress induces microglia-associated synaptic circuit alterations in the dorsomedial prefrontal cortex	22
Infralimbic cortical glutamate output is necessary for the neural and behavioral consequences of chronic stress	21
Variations in response to trauma and hippocampal subfield changes	21
Cannabis vapor self-administration elicits sex- and dose-specific alterations in stress reactivity in rats	21
Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD	21
Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress	21
The functional connectome predicts feeling of stress on regular days and during the COVID-19 pandemic	20
Fluoxetine and environmental enrichment similarly reverse chronic social stress-related depression- and anxiety-like behavior, but have differential effects on amygdala gene expression	20
Epigenetic mechanisms impacted by chronic stress across the rodent lifespan	20
Resilience or susceptibility to traumatic stress: Potential influence of the microbiome	19
Intersectional analysis of chronic mild stress-induced lncRNA-mRNA interaction networks in rat hippocampus reveals potential anti-depression/anxiety drug targets	19
Allopregnanolone (1938–2019): A trajectory of 80 years of outstanding scientific achievements	19
Dissociable roles of the nucleus accumbens core and shell subregions in the expression and extinction of conditioned fear	19
Changes in the rodent gut microbiome following chronic restraint stress and low-intensity rTMS	19
The stress susceptibility factor FKBP51 controls S-ketamine-evoked release of mBDNF in the prefrontal cortex of mice	18
Juvenile exposure to acute traumatic stress leads to long-lasting alterations in grey matter myelination in adult female but not male rats	18
Genetic evidence for a large overlap and potential bidirectional causal effects between resilience and well-being	18
Early life adversity in male mice sculpts reward circuits	18
BNST transient activity associates with approach behavior in a stressful environment and is modulated by the parabrachial nucleus	18
Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli	18
Connecting the biology of stress, allostatic load and epigenetics to social structures and processes	18
A projection from the paraventricular nucleus of the thalamus to the shell of the nucleus accumbens contributes to footshock stress-induced social avoidance	18
Long term effects of peripubertal stress on excitatory and inhibitory circuits in the prefrontal cortex of male and female mice	18
Proteomic and mitochondrial adaptations to early-life stress are distinct in juveniles and adults	18
Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models	18
Stress-induced cortisol response is associated with right amygdala volume in early childhood	18
Brain-wide mapping of c-fos expression in the single prolonged stress model and the effects of pretreatment with ACH-000029 or prazosin	18
Dual imaging of dendritic spines and mitochondria in vivo reveals hotspots of plasticity and metabolic adaptation to stress	18
The functional connectome in posttraumatic stress disorder	18

Telencephalic regulation of the HPA axis in birds	18
The cerebellum and psychological trauma: A systematic review of neuroimaging studies	17
Hippocampal-specific insulin resistance elicits behavioral despair and hippocampal dendritic atrophy	17
Prevalence of posttraumatic stress symptoms in health care workers after exposure to patients with COVID-19	17
Chronic restraint stress produces sex-specific behavioral and molecular outcomes in the dorsal and ventral rat hippocampus	17
Circulating endocannabinoids and prospective risk for depression in trauma-injury survivors	17
The social instability stress paradigm in rat and mouse: A systematic review of protocols, limitations, and recommendations	17
Sex differences in the delayed impact of acute stress on the amygdala	17
Neural impact of neighborhood socioeconomic disadvantage in traumatically injured adults	17
From genetics to systems biology of stress-related mental disorders	16
κ-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats	16
Individual baseline behavioral traits predict the resilience phenotype after chronic social defeat	16
Male long-Evans rats: An outbred model of marked hypothalamic-pituitary-adrenal hyperactivity	15
miR-34a induces spine damages via inhibiting synaptotagmin-1 in depression	15
Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue	15
miR-132 downregulation alleviates behavioral impairment of rats exposed to single prolonged stress, reduces the level of apoptosis in PFC, and upregulates the expression of MeCP2 and BDNF	15
Erasing m6A-dependent transcription signature of stress-sensitive genes triggers antidepressant actions	15
Immune system regulation and role of the human leukocyte antigen in posttraumatic stress disorder	15
Stress-induced visceral pain in female rats is associated with epigenetic remodeling in the central nucleus of the amygdala	15
Insights from a laboratory and naturalistic investigation on stress, rumination and frontal brain functioning in MDD: An fNIRS study	15
Sex differences in the effect of the FKBP5 inhibitor SAFit2 on anxiety and stress-induced reinstatement following cocaine self-administration	15
Molecular impacts of childhood abuse on the human brain	15
Effects of chronic social stress on oligodendrocyte proliferation-maturation and myelin status in prefrontal cortex and amygdala in adult mice	15
Stress enhances hippocampal neuronal synchrony and alters ripple-spike interaction	14
Childhood maltreatment results in altered deactivation of reward processing circuits in depressed patients: A functional magnetic resonance imaging study of a facial emotion recognition task	14
Placental DNA methylation marks are associated with maternal depressive symptoms during early pregnancy	14
Resource scarcity but not maternal separation provokes unpredictable maternal care sequences in mice and both upregulate Crh-associated gene expression in the amygdala	14
Reducing glutamic acid decarboxylase in the dorsal dentate gyrus attenuates juvenile stress induced emotional and cognitive deficits	14
Disinhibition of somatostatin interneurons confers resilience to stress in male but not female mice	14
Brain histamine and oleoylethanolamide restore behavioral deficits induced by chronic social defeat stress in mice	13
Sex and age differences in cognitive bias and neural activation in response to cognitive bias testing	13
Antidepressant-relevant behavioral and synaptic molecular effects of long-term fasudil treatment in chronically stressed male rats	13
Programming effects of peripubertal stress on spatial learning	13
Impact of stress resilience and susceptibility on fear learning, anxiety, and alcohol intake	13
Stress-induced changes in modular organizations of human brain functional networks	13
Low-dose S-ketamine exerts antidepressant-like effects via enhanced hippocampal synaptic plasticity in postpartum depression rats	13
Microglia-specific transcriptional repression of interferon-regulated genes after prolonged stress in mice	13
Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats	13
Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders	13
Deficits across multiple behavioral domains align with susceptibility to stress in 129S1/SvImJ mice	12
LSD1 is an environmental stress-sensitive negative modulator of the glutamatergic synapse	12
Effects of neuromodulation on cognitive and emotional responses to psychosocial stressors in healthy humans	12
Brain-wide mapping of c-Fos expression with fluorescence micro-optical sectioning tomography in a chronic sleep deprivation mouse model	12
Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence	12
Combinatorial actions of glucocorticoid and mineralocorticoid stress hormone receptors are required for preventing neurodegeneration of the mouse hippocampus	12
Contributions of PTSD polygenic risk and environmental stress to suicidality in preadolescents	12
Reversed patterns of resting state functional connectivity for females vs. males in posttraumatic stress disorder	12
Baiap3 regulates depressive behaviors in mice via attenuating dense core vesicle trafficking in subsets of prefrontal cortex neurons	12
A prospective examination of sex differences in posttraumatic autonomic functioning	12
The influence of sleep on fear extinction in trauma-related disorders	12
“Live together, die alone”: The effect of re-socialization on behavioural performance and social-affective brain-related proteins after a long-term chronic social isolation stress	12
The stress of losing sleep: Sex-specific neurobiological outcomes	12
Prebiotic supplementation modulates selective effects of stress on behavior and brain metabolome in aged mice	12
A sex-dependent delayed maturation of visual plasticity induced by adverse experiences in early childhood	11
Altered stress responses in adults born by Caesarean section	11
Regulation of stress-provoked aggressive behavior using endocannabinoids	11
Ethanol intake in male mice exposed to social defeat: Environmental enrichment potentiates resilience	11
Restoring tripartite glutamatergic synapses: A potential therapy for mood and cognitive deficits in Gulf War illness	11
Reactivating a positive feedback loop VTA-BLA-NAc circuit associated with positive experience ameliorates the attenuated reward sensitivity induced by chronic stress	11
Hormonal contraceptive phases matter: Resting-state functional connectivity of emotion-processing regions under stress	11
Forebrain overexpression of type 1 adenylyl cyclase promotes molecular stability and behavioral resilience to physical stress	11
Social support modulates the association between PTSD diagnosis and medial frontal volume in Chinese adults who lost their only child	11
Multidimensional predictors of antidepressant responses: Integrating mitochondrial, genetic, metabolic and environmental factors with clinical outcomes	11
Translational relevance of behavioral, neural, and electroencephalographic profiles in a mouse model of post-traumatic stress disorder	10
The role of the stress system in recovery after traumatic brain injury: A tribute to Bruce S. McEwen	10
Blunted neural and psychological stress processing predicts future grey matter atrophy in multiple sclerosis	10
Threat imminence reveals links among unfolding of anticipatory physiological response, cortical-subcortical intrinsic functional connectivity, and anxiety	10
Stress during puberty exerts sex-specific effects on depressive-like behavior and monoamine neurotransmitters in adolescence and adulthood	10
The effects of stress across the lifespan on the brain, cognition and mental health: A UK biobank study	10
The coupling of RACK1 with the beta isoform of the glucocorticoid receptor promotes resilience to chronic stress exposure	10
αCaMKII in the lateral amygdala mediates PTSD-Like behaviors and NMDAR-Dependent LTD	10
Longitudinal CSF proteome profiling in mice to uncover the acute and sustained mechanisms of action of rapid acting antidepressant (2R,6R)-hydroxynorketamine (HNK)	10
‘Doctor, I am so stressed out!’ A descriptive study of biological, psychological, and socioemotional markers of stress in individuals who self-identify as being ‘very stressed out’ or ‘zen’	10
In vitro modeling of the neurobiological effects of glucocorticoids: A review	10
(2R,6R)-hydroxynorketamine acts through GluA1-induced synaptic plasticity to alleviate PTSD-like effects in rat models	10
Stronger functional network connectivity and social support buffer against negative affect during the COVID-19 outbreak and after the pandemic peak	10
Dissociable impact of childhood trauma and deployment trauma on affective modulation of startle	9
Functional networks activated by controllable and uncontrollable stress in male and female rats	9
Reward sensitivity modulates the brain reward pathway in stress resilience via the inherent neuroendocrine system	9
Sex and hormonal status influence the anxiolytic-like effect of oxytocin in mice	9

Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (Nav) channels properties	9
Differences in gut microbiota associated with stress resilience and susceptibility to single prolonged stress in female rodents	9
Maternal adverse childhood experiences and infant subcortical brain volume	9
Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons	9
Corticosterone dynamically regulates retrotransposable element expression in the rat hippocampus and C6 cells	9
Amygdala size varies with stress perception	9
Bacteria - derived short chain fatty acids restore sympathoadrenal responsiveness to hypoglycemia after antibiotic-induced gut microbiota depletion	9
Adult food choices depend on sex and exposure to early-life stress: Underlying brain circuitry, adipose tissue adaptations and metabolic responses	9
The amygdala mediates the facilitating influence of emotions on memory through multiple interacting mechanisms	9
Neural connectome prospectively encodes the risk of post-traumatic stress disorder (PTSD) symptom during the COVID-19 pandemic	9
The role of TET proteins in stress-induced neuroepigenetic and behavioural adaptations	9
A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders	9
Sex differences in the association between basal serum cortisol concentrations and cortical thickness	9
Evolution of stress responses refine mechanisms of social rank	8
Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity	8
Roles of corticotropin-releasing factor signaling in the lateral habenula in anxiety-like and alcohol drinking behaviors in male rats	8
Impact of stress on inhibitory neuronal circuits, our tribute to Bruce McEwen	8
Neurobiological effects of phospholipids in vitro: Relevance to stress-related disorders	8
Allopregnanolone: Regenerative therapeutic to restore neurological health	8
Validation of an Electrochemical Sensor to Detect Cortisol Responses to the Trier Social Stress Test	8
Transcriptomics of the depressed and PTSD brain	8
Ventral hippocampal diacylglycerol lipase-alpha deletion decreases avoidance behaviors and alters excitation-inhibition balance	8
Is neuroticism really bad for you? Dynamics in personality and limbic reactivity prior to, during and following real-life combat stress	8
Stress induces divergent gene expression among lateral habenula efferent pathways	8
Consideration of sex as a biological variable in the translation of pharmacotherapy for stress-associated drug seeking	8
Inhibition of adult neurogenesis reduces avoidance behavior in male, but not female, mice subjected to early life adversity	8
Remembering and forgetting in sleep: Selective synaptic plasticity during sleep driven by scaling factors Homer1a and Arc	8
Riluzole prevents stress-induced spine plasticity in the hippocampus but mimics it in the amygdala	8
Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex	8
Specific sub-regions along the longitudinal axis of the hippocampus mediate antidepressant-like behavioral effects	8
Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans	8
Optogenetically-induced long term depression in the rat orbitofrontal cortex ameliorates stress-induced reversal learning impairment	8
Molecular characterization of the stress network in individuals at risk for schizophrenia	7
Relationship between psychosocial stress-induced prefrontal cortex activity and gut microbiota in healthy Participants—A functional near-infrared spectroscopy study	7
Longitudinal monitoring of prefrontal cortical ensemble dynamics reveals new insights into stress habituation	7
Behavioral, neurochemical, and neuroimmune changes associated with social buffering and stress contagion	7
Acute stress blunts prediction error signals in the dorsal striatum during reinforcement learning	7
Neural activity during response inhibition in mild traumatic brain injury and posttraumatic stress disorder	7
Genomic factors underlying sex differences in trauma-related disorders	7
Brain activity during a post-stress working memory task differs between the hormone-present and hormone-absent phase of hormonal contraception	7
Blockade of nociceptin/orphanin FQ signaling facilitates an active copying strategy due to acute and repeated stressful stimuli in mice	7
Genomic regulation of Krüppel-like-factor family members by corticosteroid receptors in the rat brain	7
Chronic ethanol alters adrenergic receptor gene expression and produces cognitive deficits in male mice	7
Stress enhances emotional memory-related theta oscillations in the medial temporal lobe	7
Pubertal changes in the pituitary and adrenal glands of male and female rats: Relevance to stress reactivity	6
Stress and the brain: Emotional support mediates the association between myelination in the right supramarginal gyrus and perceived chronic stress	6
An allostatic epigenetic memory on chromatin footprints after double-hit acute stress	6
Acute stress alters recognition memory and AMPA/NMDA receptor subunits in a sex-dependent manner	6
Modeling integrated stress, sleep, fear and neuroimmune responses: Relevance for understanding trauma and stress-related disorders	6
Brain-Derived Neurotrophic Factor Val66Met polymorphism interacts with adolescent stress to alter hippocampal interneuron density and dendritic morphology in mice	6
Amygdalar endocannabinoids are affected by predator odor stress in a sex-specific manner and modulate acoustic startle reactivity in female rats	6
Choosing memory retrieval strategies: A critical role for inhibition in the dentate gyrus	6
Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats	6
Lifelong impact of extreme stress on the human brain: Holocaust survivors study	6
Acute stress impairs sensorimotor gating via the neurosteroid allopregnanolone in the prefrontal cortex	6
Dihydromyricetin ameliorates social isolation-induced anxiety by modulating mitochondrial function, antioxidant enzymes, and BDNF	6
Deletion of hippocampal Glucocorticoid receptors unveils sex-biased microRNA expression and neuronal morphology alterations in mice	6
Amygdala and hippocampal subregions mediate outcomes following trauma during typical development: Evidence from high-resolution structural MRI	6
Sex differences in endocannabinoid modulation of rat CA1 dendritic neurotransmission	6
Dl-3-n-Butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation	6
The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus	6
Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition	6
Alcohol and stress exposure across the lifespan are key risk factors for Alzheimer's Disease and cognitive decline	6
Glucagon-like peptide 1 receptor-mediated stimulation of a GABAergic projection from the bed nucleus of the stria terminalis to the hypothalamic paraventricular nucleus	6
B2 SINE RNA as a novel regulator of glucocorticoid receptor transcriptional activity	6
The habenula clock influences response to a stressor	6
Estrogen receptor beta in the central amygdala regulates the deleterious behavioral and neuronal consequences of repeated social stress in female rats	6
Impact of acute psychosocial stress on attentional control in humans. A study of evoked potentials and pupillary response	6
The interaction between social hierarchy and depression/anxiety: Involvement of glutamatergic pyramidal neurons in the medial prefrontal cortex (mPFC)	6
Chronic hypothalamic-pituitary-adrenal axis disruption alters glutamate homeostasis and neural responses to stress in male C57Bl6/N mice	6