OOIR: Observatory of International Research

Papers

(The TQCC of Biomedical Journal is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)

Article	Citations
Polycystic kidney disease increases the stoke incidence in Taiwan: A retrospective population-based cohort study using National Health Insurance Database	146
HIF-1 AND DEC-1 LEVELS IN ACUTE ISCHAEMIC STROKE PATIENTS: COULD DEC-1 BE A NEW BIOMARKER IN STROKE?	69
Fu's Subcutaneous Needling Therapy Significantly Enhances Pain Relief in Sciatica Rats by Promoting Mitochondrial Autophagy	61
Antrodia cinnamomea extract alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting the mTOR pathway	60
New concepts for glioblastoma vaccine immunotherapy	60
Roles of lncRNAs in the transcription regulation of HIV-1	52
Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy	51
Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study	48
Aptamer-functionalized liposomes for drug delivery	45
m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle	42
Bilateral lentiform and caudate nucleus lesions in a child with COVID-19: A case report	40
When it doesn't run in the blood(vessels) – events involved in vascular disorders	39
Editorial Board	38
The effects of macronutrients metabolism on cellular and organismal aging	36
Comprehensive insight into the alterations in the gut microbiome and the intestinal barrier as a consequence of iron deficiency anaemia	36
Lifestyle interventions to delay senescence	35
Saliva as a diagnostic tool to measure polycyclic aromatic hydrocarbon exposure in dental patients exposed to intimate partner violence (IPV)	35
Clinical and genomic insights into persistent carbapenem-resistant Klebsiella pneumoniae bacteremia: risk factors, resistance mechanisms, and treatment challenges	34
Tools to measure membrane potential of neurons	34
Macrophages in the male genital tract	32
Artificial intelligence in infection surveillance: Data integration, applications and future directions	31
The establishment of a molecular diagnostic platform for mitochondrial diseases: From conventional to next-generation sequencing	31
High-throughput proteomics-guided biomarker discovery of hepatocellular carcinoma	30
Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15	29
Additional insights on SARS-CoV-2 spike protein variants and red blood cells biology	29

Influence of acupuncture twisting parameters on analgesic effects mediated by mast cells in AA rat models	28
Discrepant treponemal test results: Identification of associated risk factors through machine learning technology in 18-year electronic medical records and national claims data	27
A panel of miRNAs in serum extracellular vesicles serves as novel diagnostic biomarkers for MASLD	27
Editorial Board	27
Using time-course as an essential factor to accurately predict sepsis-associated mortality among patients with suspected sepsis	26
Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat	26
Discharge status validation of the Chang Gung Research database in Taiwan	26
Dynamic regulation of RNA m6A methylation in the ribonucleoprotein complexes in apicomplexan and kinetoplastid parasites	26
Circadian rhythmicity and human health	25
Advancements, challenges, and future prospects in clinical hyperpolarized magnetic resonance imaging: A comprehensive review	25
Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease	24
Automatic and human level Graf's type identification for detecting developmental dysplasia of the hip	24
“Mpox in MSM: Tackling stigma, minimizing risk factors, exploring pathogenesis, and treatment approaches”	23
Lymphedema imaging and AI: A review of diagnostic modalities, biomarkers, and clinical integration	23
Developmental origins and environmental determinants of cardiovascular–kidney–metabolic syndrome: A pediatric precision prevention perspective	23
Angular super-resolution in X-ray projection radiography using deep neural network: Implementation on rotational angiography	22
Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation	22
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head	22
Revisiting the safety of short-term systemic corticosteroids	22
Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer	21
Nod-like receptors in inflammatory arthritis	21
Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery	21
Comparing transvenous coiling and transarterial embolization with Onyx/NBCA for cavernous sinus dural arteriovenous fistulas: A retrospective study in a single center	21
Response to "letter to editor" from Nicolini et al. Regarding "Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study"	20
Multifunctional nanozymes for disease diagnosis and therapy	20
Fecal miRNAs as potential biomarkers for early detection of colorectal cancer: An updated review	20
Ancient wisdom and modern innovations: Methods of administering healing	20
Systematic analysis of mushroom body-innervating dopaminergic neuron activity in different physiological states in Drosophila	20
Hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer	19
SARS-CoV-2 variants – Evolution, spike protein, and vaccines	18
Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer	18
Long non-coding RNAs as modulators of metabolic reprogramming for endogenous heart regeneration: Mechanisms and therapeutic potential	18
Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes	18
Advancing cancer diagnosis and treatment: Integrating molecular biomarkers and emerging technologies	18
Circ_0091579 exerts an oncogenic role in hepatocellular carcinoma via mediating miR-136-5p/TRIM27	18
Current efforts and challenges facing responses to Monkeypox in United Kingdom	17
In vitro axotomy models regulated by ROCK inhibitor for studying neuroregeneration and growth cone morphology	17
Extracellular vesicles in fetal-maternal immune tolerance	17
CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden	17
Inhibition of the 4-hydroxynonenal-regulated JNK/c-Jun pathway improves bleomycin-induced lung fibrosis	17
Strides toward a better understanding of the “Current efforts and challenges facing responses to Monkeypox in United Kingdom”	17
Chronic low-dose REV-ERBs agonist SR9009 mitigates constant light-induced weight gain and insulin resistance via adipogenesis modulation	16
Editorial Board	16
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer	16
The epidemiology of invasive fungal infections in transplant recipients	16
Inherently imperfect, inherently evolving – The pursuit of precision through biomarkers	16
Author reply to letter to the editor “Imaging abnormalities in pediatric neuro-COVID are more diverse than specified”	15
Altered diffusivity of the subarachnoid cisterns in the rat brain following neurological disorders	15
Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease	15
Macrophages of the heart: Homeostasis and disease	15

Utilizing nomograms to predict prevalent vertebral fracture risk: An analysis of dysmobility syndrome in a community-dwelling population	15
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism	15
Targeted dexamethasone nano-prodrug for corneal neovascularization management	15
Clinical significance of incidental common bile duct dilatation in children: A 10-year single medical center experience	15
Mouth opening/breathing is common in sleep apnea and linked to more nocturnal water loss	14
Impact of Genetic Variants in Cyclophosphamide-Metabolizing Enzymes on Clinical Outcomes After Haploidentical Hematopoietic Stem Cell Transplantation	13
A comprehensive overview of gastric cancer management from a surgical point of view	13
Editorial Board	13
Prognosis of chronic kidney disease in patients with non-alcoholic fatty liver disease: a Northeastern Taiwan community medicine research cohort	13
Phylogenetic characteristics of Non-SARS human coronavirus in southern Taiwan, 2012–2013	13
Factors associated with pyloric hypertrophy severity and post-operative feeding and nutritional recovery in infantile hypertrophic pyloric stenosis	13
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate	12
Distinct subtypes of kidney transplant-associated urothelial carcinomas harboring BK polyomavirus integration and aristolochic acid mutational signatures	12
Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway	12
Glomerular disease classification and lesion identification by machine learning	12
Practical applications of grounding to support health	12
Editorial Board	12
Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease	12
Evolutionary Conservation, Expansion and Diversification of Interferon stimulated genes (ISG) in Vertebrates: insights from fish	12
COVID-19 vaccination uptake strongly predicts averted deaths of older people across Europe	12
Biological functions of extracellular vesicles from mammalian cells	12
Plasminogen activator Inhibitor-1 in systemic sclerosis: A nexus of fibrosis, vasculopathy, and senescence	11
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management	11
Kinship analysis of type 2 diabetes mellitus familial aggregation in Taiwan	11
LncRNAs and asymmetric cell division: The epigenetic mechanisms	11
Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens	11
The clockwork macrophage: Timing in innate immunity	11
Genomic surveillance of SARS-CoV-2 in Taiwan: A perspective on evolutionary data interpretation and sequencing issues	11
ShinySC: An R/Shiny-based desktop application for seamless analysis of scRNA-Seq data	11
The 2022 nobel prize in physiology or medicine awarded for the decoding of the complete ancient human genome	11
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication	11