OOIR: Observatory of International Research

Papers

(The TQCC of Biomedical Journal is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
DNA copy number variation: Main characteristics, evolutionary significance, and pathological aspects	120
Innate immunity drives pathogenesis of rheumatoid arthritis	109
Understanding the role of neutrophils in acute respiratory distress syndrome	100
Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation	83
G6PD: A hub for metabolic reprogramming and redox signaling in cancer	47
Development of multi-epitope peptide-based vaccines against SARS-CoV-2	45
Lopinavir/ritonavir: Repurposing an old drug for HIV infection in COVID-19 treatment	44
Perilla (Perilla frutescens) leaf extract inhibits SARS-CoV-2 via direct virus inactivation	43
LncRNA MALAT1 promotes breast cancer progression and doxorubicin resistance via regulating miR-570–3p	37
Neutralizing monoclonal antibodies for COVID-19 treatment and prevention	37
SARS-CoV-2, the other face to SARS-CoV and MERS-CoV: Future predictions	37
RASopathies: From germline mutations to somatic and multigenic diseases	36
Effects of physical exercise on children with attention deficit hyperactivity disorder	34
SARS-CoV-2 variants – Evolution, spike protein, and vaccines	34
Exploring algae and cyanobacteria as a promising natural source of antiviral drug against SARS-CoV-2	31
Lymphoid Tissue inducer (LTi) cell ontogeny and functioning in embryo and adult	30
Breath volatile organic compounds (VOCs) as biomarkers for the diagnosis of pathological conditions: A review	30
Exposure to PM2.5 and PM10 and COVID-19 infection rates and mortality: A one-year observational study in Poland	29
The role of GPR56/ADGRG1 in health and disease	29
Effects of electronic cigarette aerosol exposure on oral and systemic health	28
Phytochemicals against SARS-CoV as potential drug leads	27
Glomerular disease classification and lesion identification by machine learning	27
Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype	27
3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting	27
Artificial neural network and logistic regression modelling to characterize COVID-19 infected patients in local areas of Iran	25

The respiratory impacts of air pollution in children: Global and domestic (Taiwan) situation	25
Role of bacterial infections in extracellular vesicles release and impact on immune response	25
Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes	24
Modified ELISA for antibody avidity evaluation: The need for standardization	24
Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease	24
Brain stimulation treatments in epilepsy: Basic mechanisms and clinical advances	23
Immunotherapy in older patients with cancer	22
Pediatric care for children with developmental coordination disorder, can we do better?	22
The genetic landscape of the FAS pathway deficiencies	22
Sex hormone regulation of innate lymphoid cells	21
Targeting mitochondrial bioenergetics as a promising therapeutic strategy in metabolic and neurodegenerative diseases	21
Cellular senescence and the host immune system in aging and age-related disorders	21
A recipe for a good clinical pulmonary surfactant	20
The role and mechanism of CARD9 gene polymorphism in diseases	20
Role of SARS-CoV-2 and ACE2 variations in COVID-19	19
The Notch signaling pathway involvement in innate lymphoid cell biology	19
Type 1 innate lymphoid cells: Soldiers at the front line of immunity	19
The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis	19
Updates on the ketogenic diet therapy for pediatric epilepsy	18
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function	17
Development and validation of a deep-learning-based pediatric early warning system: A single-center study	17
Intravascular Large B-cell lymphoma: A case series and review of literatures	17
Roles of lncRNAs in the transcription regulation of HIV-1	16
A novel CAD/CAM composite occlusal splint for intraoperative verification in single-splint two-jaw orthognathic surgery	16
Personalized medicine: From diagnostic to adaptive	15
Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort	15
Discharge status validation of the Chang Gung Research database in Taiwan	15
A multicompartment vascular implant of electrospun wintergreen oil/ polycaprolactone fibers coated with poly(ethylene oxide)	15
Impact of prepregnancy body mass index on pregnancy outcomes, incidence of urinary incontinence and quality of life during pregnancy - An observational cohort study	14
Circ_0091579 exerts an oncogenic role in hepatocellular carcinoma via mediating miR-136-5p/TRIM27	14
Postnatal intestinal mucosa and gut microbial composition develop hand in hand: A mouse study	14
Pristimerin exerts antitumor activity against MDA-MB-231 triple-negative breast cancer cells by reversing of epithelial-mesenchymal transition via downregulation of integrin β3	14
Suppression of MGAT3 expression and the epithelial–mesenchymal transition of lung cancer cells by miR-188-5p	14
Current and future applications of fecal microbiota transplantation for children	14
Modification of brain waves and sleep parameters by Citrus reticulata Blanco. cv. Sai-Nam-Phueng essential oil	14
5-day multi-session intermittent theta burst stimulation over bilateral posterior superior temporal sulci in adults with autism-a pilot study	14
Immunoinformatics prediction of potential B-cell and T-cell epitopes as effective vaccine candidates for eliciting immunogenic responses against Epstein–Barr virus	14
A brief review on potential application of mesenchymal stem cell and secretome in combating mortality and morbidity in COVID-19 patients	13
Current understanding of the genetics of Tourette syndrome	13
Bone marrow-derived mesenchymal stem cells transplantation ameliorates renal injury through anti-fibrotic and anti-inflammatory effects in chronic experimental renovascular disease	13
Spectrum of neuroimaging mimics in children with COVID-19 infection	13
Low energy shock wave therapy attenuates mitochondrial dysfunction and improves bladder function in HCl induced cystitis in rats	13
Tools to measure membrane potential of neurons	13
Therapeutic effect of bone marrow mesenchymal stem cells in a rat model of carbon tetrachloride induced liver fibrosis	13
Cell therapy in vascularized composite allotransplantation	13
Metabolomics as a promising tool for improving understanding of multiple sclerosis: A review of recent advances	13
Typical and atypical enteropathogenic Escherichia coli in children with acute diarrhoea: Changing trend in East Delhi	13
Time course and epidemiological features of COVID-19 resurgence due to cold-chain food or packaging contamination	13
Complementary effects of Orthosiphon stamineus standardized ethanolic extract and rosmarinic acid in combination with gemcitabine on pancreatic cancer	12
Tourette disorder and sleep	12

High levels estradiol affect blastocyst implantation and post-implantation development directly in mice	12
COVID-19 and gastrointestinal system: A brief review	12
Bladder volume reproducibility after water consumption in patients with prostate cancer undergoing radiotherapy: A systematic review and meta-analysis	12
3-Hydroxybenzaldehyde and 4-Hydroxybenzaldehyde enhance survival of mouse astrocytes treated with Angiostrongylus cantonensis young adults excretory/secretory products	12
The role of endocytic trafficking in antigen T cell receptor activation	11
Endoscopic transcanal removal of external auditory canal osteomas	11
Functional roles of non-coding RNAs regulated by thyroid hormones in liver cancer	11
Evaluation of recurrence risk in patients with papillary thyroid cancer through tumor-node-metastasis staging: A single-center observational study in Taiwan	11
Current efforts and challenges facing responses to Monkeypox in United Kingdom	11
Strategies to protect surfactant and enhance its activity	11
Hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer	10
Integrative immunoinformatics paradigm for predicting potential B-cell and T-cell epitopes as viable candidates for subunit vaccine design against COVID-19 virulence	10
Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation	10
Circulating tumor cell enumeration for improved screening and disease detection of patients with colorectal cancer	10
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management	10
LncRNA OIP5-AS1 reduces renal epithelial cell apoptosis in cisplatin-induced AKI by regulating the miR-144-5p/PKM2 axis	10
Comparison of the Roche cobas 6800 SARS-CoV-2 test and the Taiwan CDC protocol for the molecular diagnosis of COVID-19	10
Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer	10
Recovery of walking ability in stroke patients through postacute care rehabilitation	10
Modified natriuretic peptides and their potential roles in cancer treatment	10
Association of preoperative frailty and postoperative delirium in older cancer patients undergoing elective abdominal surgery: A prospective observational study in Taiwan	10
Applications of three-dimensional imaging techniques in craniomaxillofacial surgery: A literature review	10
Cardiac troponin elevation in patients with influenza virus infections	10
Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease	10
Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease	10
Short-term and long-term psychological impact and quality of life of patients undergoing orthognathic surgery	9
MicroRNAs (−146a, −21 and −34a) are diagnostic and prognostic biomarkers for diabetic retinopathy	9
Regenerative medicine for male infertility: A focus on stem cell niche injury models	9
Long non-coding RNA LINC01559 serves as a competing endogenous RNA accelerating triple-negative breast cancer progression	9
Different impacts of common risk factors associated with thrombocytopenia in patients with hepatitis B virus and hepatitis C virus infection	9
Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease	9
Hemodynamic monitoring and management of pediatric septic shock	9
Race with virus evolution: The development and application of mRNA vaccines against SARS-CoV-2	9
Antisiphon device: A review of existing mechanisms and clinical applications to prevent overdrainage in shunted hydrocephalic patients	9
Infection control operations of a large hospital in Taiwan to prevent nosocomial outbreaks during COVID-19 pandemic	9
Innate type 1 immune response, but not IL-17 cells control tuberculosis infection	8
Gastrodia elata and parishin ameliorate aging induced ‘leaky gut’ in mice: Correlation with gut microbiota	8
A review for cell and particle tracking on microscopy images using algorithms and deep learning technologies	8
Performance of two frailty screening tools among patients with cancer in Taiwan	8
Fibroblast growth factor 21 and bone homeostasis	8
Progesterone eliminates 17β-estradiol-Mediated cardioprotection against diabetic cardiovascular dysfunction in ovariectomized rats	8
Clinical features, laboratory findings and persistence of virus in 10 children with coronavirus disease 2019 (COVID-19)	8
c-MYC/METTL3/LINC01006 positive feedback loop promotes migration, invasion and proliferation of non-small cell lung cancer	8
Undergraduates’ preparedness for practice is associated with professional identity and perception of educational environment: A validation study	8
MicroRNA-based signature for diagnosis and prognosis of colorectal cancer using residuum of fecal immunochemical test	8
Comparison of the outcome of emergency endotracheal intubation in the general ward, intensive care unit and emergency department	8
Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury	8
Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress	8
Negative times negative equals positive, THEMIS sets the rule on thymic selection and peripheral T cell responses	8
Acupressure reduces the severity of restless legs syndrome in hemodialysis patients: A cluster-randomized crossover pilot study	8
The Yin and the Yang of extracellular vesicles during viral infections	8
The combination of low level laser therapy and efavirenz drastically reduces HIV infection in TZM-bl cells	8
The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy	8