Biomedical Journal

Article	Citations
Living with tics: Nursing care of pediatric Tourette syndrome	187
Antrodia cinnamomea extract alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting the mTOR pathway	146
Polycystic kidney disease increases the stoke incidence in Taiwan: A retrospective population-based cohort study using National Health Insurance Database	74
One day at a time	73
The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis	50
Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study	44
Roles of lncRNAs in the transcription regulation of HIV-1	43
Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy	40
Aptamer-functionalized liposomes for drug delivery	39
Editorial Board	39
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function	39
Editorial Board	38
Editorial Board	35
When it doesn't run in the blood(vessels) – events involved in vascular disorders	35
Bilateral lentiform and caudate nucleus lesions in a child with COVID-19: A case report	34
The establishment of a molecular diagnostic platform for mitochondrial diseases: From conventional to next-generation sequencing	32
The effects of macronutrients metabolism on cellular and organismal aging	30
High-throughput proteomics-guided biomarker discovery of hepatocellular carcinoma	30
Comprehensive insight into the alterations in the gut microbiome and the intestinal barrier as a consequence of iron deficiency anaemia	29
m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle	28
Clinical and genomic insights into persistent carbapenem-resistant Klebsiella pneumoniae bacteremia: risk factors, resistance mechanisms, and treatment challenges	27
Lifestyle interventions to delay senescence	26
Middle cerebral artery velocity is associated with the severity of MRI brain injury in neonates received therapeutic hypothermia	26
Implementation of fecal microbiota transplantation in a medical center for recurrent or refractory Clostridioides difficile infection and report of preliminary outcome	25
Saliva as a diagnostic tool to measure polycyclic aromatic hydrocarbon exposure in dental patients exposed to intimate partner violence (IPV)	25

Tools to measure membrane potential of neurons	25
Eligibility for live, interactive otolaryngology telemedicine: 19-Month experience before and during the COVID-19 pandemic in Taiwan	24
Macrophages in the male genital tract	24
Influence of acupuncture twisting parameters on analgesic effects mediated by mast cells in AA rat models	23
Glycolytic metabolism and activation of Na+ pumping contribute to extracellular acidification in the central clock of the suprachiasmatic nucleus: Differential glucose sensitivity and utilization betw	23
Discharge status validation of the Chang Gung Research database in Taiwan	22
The binding and specificity of chemokine binding proteins, through the lens of experiment and computation	21
Long non-coding RNA HAGLROS facilitates the malignant phenotypes of NSCLC cells via repressing miR-100 and up-regulating SMARCA5	21
Additional insights on SARS-CoV-2 spike protein variants and red blood cells biology	20
Grafted bone remodeling following transcrestal sinus floor elevation: A cone-beam computed tomography study	20
Using time-course as an essential factor to accurately predict sepsis-associated mortality among patients with suspected sepsis	20
Circadian rhythmicity and human health	20
Purinergic signaling: A new front-line determinant of resistance and susceptibility in leishmaniasis	19
Automatic and human level Graf's type identification for detecting developmental dysplasia of the hip	19
A panel of miRNAs in the serum extracellular vesicles serve as novel diagnostic biomarkers for MASLD	19
Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation	19
Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15	19
Discrepant Treponemal Test Results: Identification of Associated Risk Factors Through Machine Learning Technology in 18-Year Electronic Medical Records and National Claims Data	18
Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat	18
Angular super-resolution in X-ray projection radiography using deep neural network: Implementation on rotational angiography	18
Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease	18
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head	18
Advancements, challenges, and future prospects in clinical hyperpolarized magnetic resonance imaging: A comprehensive review	18
Dynamic Regulation of RNA m6A Methylation in the Ribonucleoprotein Complexes in Apicomplexan and Kinetoplastid Parasites	18
“Mpox in MSM: Tackling stigma, minimizing risk factors, exploring pathogenesis, and treatment approaches”	18
Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer	18
Surgery for metastatic epidural spinal cord compression in thoracic spine, anterior or posterior approach?	17
Nod-like receptors in inflammatory arthritis	17
Low energy shock wave therapy attenuates mitochondrial dysfunction and improves bladder function in HCl induced cystitis in rats	17
Endothelial activation, cell-cell interactions, and inflammatory pathways in postoperative atrial fibrillation following cardiac surgery	17
Hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer	17
Fecal miRNAs as potential biomarkers for early detection of colorectal cancer: An updated review	17
Comparing transvenous coiling and transarterial embolization with Onyx/NBCA for cavernous sinus dural arteriovenous fistulas: A retrospective study in a single center	17
Multifunctional nanozymes for disease diagnosis and therapy	17
Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer	17
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM)	17
A finger in every pie – The versatility of chemokines	17
Systematic analysis of mushroom body-innervating dopaminergic neuron activity in different physiological states in Drosophila	17
Response to "letter to editor" from Nicolini et al. Regarding "Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study"	16
Advancing cancer diagnosis and treatment: Integrating molecular biomarkers and emerging technologies	16
Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes	16
Ancient wisdom and modern innovations: Methods of administering healing	16
The incidence of resistance-associated variants to NS5A in HCV subtypes 1a and 1b in Taiwan	16
In vitro axotomy models regulated by ROCK inhibitor for studying neuroregeneration and growth cone morphology	15
Current efforts and challenges facing responses to Monkeypox in United Kingdom	15
Extracellular vesicles in fetal-maternal immune tolerance	15
SARS-CoV-2 variants – Evolution, spike protein, and vaccines	15
Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer	15
Circ_0091579 exerts an oncogenic role in hepatocellular carcinoma via mediating miR-136-5p/TRIM27	15
Clinical and functional characteristics of lung surgery-related vocal fold palsy	14

Chronic low-dose REV-ERBs agonist SR9009 mitigates constant light-induced weight gain and insulin resistance via adipogenesis modulation	14
CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden	14
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer	14
Utilizing nomograms to predict prevalent vertebral fracture risk: An analysis of dysmobility syndrome in a community-dwelling population	13
Autophagy-induced osteoblast-derived exosomes maintain bone formation and prevent osteoporosis by remodeling gut microbiota-metabolism	13
Editorial Board	13
Inherently imperfect, inherently evolving – The pursuit of precision through biomarkers	13
The epidemiology of invasive fungal infections in transplant recipients	13
The best protection is early detection	13
Clinical significance of incidental common bile duct dilatation in children: A 10-year single medical center experience	13
Author reply to letter to the editor “Imaging abnormalities in pediatric neuro-COVID are more diverse than specified”	13
Joint effects of genomic markers and urinary methylation capacity associated with inorganic arsenic metabolism on the occurrence of cancers among residents in arseniasis-endemic areas: A cohort subset	13
Altered diffusivity of the subarachnoid cisterns in the rat brain following neurological disorders	13
Macrophages of the Heart: Homeostasis and Disease	13
Targeted dexamethasone nano-prodrug for corneal neovascularization management	13
Strides toward a better understanding of the “Current efforts and challenges facing responses to Monkeypox in United Kingdom”	13
Pharmacological therapy for Tourette syndrome: What medicine can do and cannot do	13
Editorial Board	12
A CD33 frameshift variant is associated with neuromyelitis optica spectrum disorders	12
Biological functions of extracellular vesicles from mammalian cells	12
Phylogenetic characteristics of Non-SARS human coronavirus in southern Taiwan, 2012–2013	12
Mouth opening/breathing is common in sleep apnea and linked to more nocturnal water loss	12
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate	12
Factors associated with pyloric hypertrophy severity and post-operative feeding and nutritional recovery in infantile hypertrophic pyloric stenosis	12
Glomerular disease classification and lesion identification by machine learning	12
Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease	12
Comparison of the outcome of emergency endotracheal intubation in the general ward, intensive care unit and emergency department	12
Prognosis of chronic kidney disease in patients with non-alcoholic fatty liver disease: a Northeastern Taiwan community medicine research cohort	12
A comprehensive overview of gastric cancer management from a surgical point of view	12
COVID-19 vaccination uptake strongly predicts averted deaths of older people across Europe	11
Infection control operations of a large hospital in Taiwan to prevent nosocomial outbreaks during COVID-19 pandemic	11
Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway	11
Editorial Board	11
Complementary effects of Orthosiphon stamineus standardized ethanolic extract and rosmarinic acid in combination with gemcitabine on pancreatic cancer	11
ShinySC: an R/Shiny-based desktop application for seamless analysis of scRNA-Seq data	11
The clockwork macrophage: timing in innate immunity	10
Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease	10
The 2022 nobel prize in physiology or medicine awarded for the decoding of the complete ancient human genome	10
Plasminogen Activator Inhibitor-1 in Systemic Sclerosis: A Nexus of Fibrosis, Vasculopathy, and Senescence	10
Practical applications of grounding to support health	10
Genomic surveillance of SARS-CoV-2 in Taiwan: A perspective on evolutionary data interpretation and sequencing issues	10
Kinship analysis of type 2 diabetes mellitus familial aggregation in Taiwan	10
LncRNAs and asymmetric cell division: The epigenetic mechanisms	10
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management	10
Editorial Board	10
Editorial Board	10
The role of endocytic trafficking in antigen T cell receptor activation	9
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction	9
Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens	9
Effects of light, electromagnetic fields and water on biological rhythms	9
SLC7A11-HSPB1 Axis: A Novel Mechanism for Hepatocellular Carcinoma Progression and Ferroptosis Regulation	9
A review for cell and particle tracking on microscopy images using algorithms and deep learning technologies	9
Applications of three-dimensional imaging techniques in craniomaxillofacial surgery: A literature review	9
Real-world effectiveness of intravitreal dexamethasone implants - Comparison between eyes eligible and ineligible for clinical trials and their associated outcomes	9
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication	9
BrainView: A Cloud-based Deep Learning System for Brain Image Segmentation, Tumor Detection and Visualization	9
The next generation of healthcare ecosystem in the metaverse	9
Editorial Board	9
The International Week of Surfactant Research: Increasing knowledge about surfactant and unexploited opportunities	8
Novel approach by natural language processing for COVID-19 knowledge discovery	8
Techniques to evaluate surfactant activity for a personalized therapy of RDS neonates	8
PAI-1 is a common driver of aging and diverse diseases	8
c-MYC/METTL3/LINC01006 positive feedback loop promotes migration, invasion and proliferation of non-small cell lung cancer	8
Deep learning significantly boosts CRT response prediction using synthetic longitudinal strain data: Training on synthetic data and testing on real patients	8
The efficacies of non-bismuth containing quadruple therapies in the treatment of first-line anti-Helicobacter pylori across 4-year time interval with changing antibiotics resistance	8
Differential longitudinal effects of frequent sweetened food consumption at different exposure ages on child cognitive, language, and motor development	8
Clinical studies on coronavirus disease 2019 (COVID-19) in the WHO registry network	8
Genome-wide association study identifies DRAM1 associated with Tourette syndrome in Taiwan	8
Increased macrophage activation marker soluble CD163 is associated with graft dysfunction and metabolic derangements in renal transplant recipients	8
MicroRNAs (−146a, −21 and −34a) are diagnostic and prognostic biomarkers for diabetic retinopathy	8
An area of greatest vulnerability - Recent advances in kidney injury	8
Small and mighty – microRNAs pulling the strings	8
SARS-CoV-2 pandemics: An update of CRISPR in diagnosis and host–virus interaction studies	8
Interferon-alpha and MxA inhibit BK polyomavirus replication by interaction with polyomavirus large T antigen	8
Different impacts of common risk factors associated with thrombocytopenia in patients with hepatitis B virus and hepatitis C virus infection	8
Modification of brain waves and sleep parameters by Citrus reticulata Blanco. cv. Sai-Nam-Phueng essential oil	7
Role of purinoreceptors in the release of extracellular vesicles and consequences on immune response and cancer progression	7
Disposition of embryos from women who only produced morphologically poor embryos on day three	7
Hepatocyte nuclear factor 4 located in different developmental stages of Schistosoma japonicum and involved in important metabolic pathways	7
Rhythms under tension: Circadian clocks in an Unsynced Society	7

Afterhyperpolarization potential modulated by local [K+]o in K+ diffusion-restricted extracellular space in the central clock of suprachiasmatic nucleus	7
Percentage genome change and chromosome 7q amplification predict sorafenib response in advanced hepatocellular carcinoma	7
Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress	7
Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation	7
Editorial Board	7
Reading the epitranscriptome of the human malaria parasite	7
Impact of fasting & ketogenic interventions on the NLRP3 inflammasome: A narrative review	7
Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	7
LncRNA OIP5-AS1 reduces renal epithelial cell apoptosis in cisplatin-induced AKI by regulating the miR-144-5p/PKM2 axis	7
Mitochondrial bioenergetics deficiency in cisd-1 mutants is linked to AMPK-mediated lipid metabolism	7
Using A modified quickert procedure combined with prolapsed fat and preseptal orbicularis muscle removal to correct involutional lower eyelid entropion in Asians	7
Basic implications on three pathways associated with SARS-CoV-2	7
Mutations in circulating tumor DNA detected in the postoperative period predict poor survival in patients with ovarian cancer	7
Impact of Vertical Facial Patterns on Three-Dimensional Surgical Outcomes and Stability in Skeletal Class II Malocclusion	6
Postnatal intestinal mucosa and gut microbial composition develop hand in hand: A mouse study	6
Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis	6
TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population	6
Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients	6
Palatal hybrid surgery for obstructive sleep apnea-state-of-the-art annotation of uvulopalatopharyngoplasty	6
Correlation of SALL1 with CEUS Parameters and Immune Escape in Thyroid Carcinoma	6
Prevention and treatment of COVID-19 infection by earthing	6
The effects of bone-substitute augmentation on treatment of osteoporotic intertrochanteric fractures	6
Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling	6
Editorial Board	6
Differential bicistronic gene translation mediated by the internal ribosome entry site element of encephalomyocarditis virus	6
Would foot arch development in children characterize a body maturation process? A prospective longitudinal study	6
Changing life styles for children with Tourette syndrome	6
The combination of low level laser therapy and efavirenz drastically reduces HIV infection in TZM-bl cells	6
In-vitro and in-vivo functional observation studies to establish therapeutic potential of alpha-ketoglutarate against methotrexate induced liver injury	6
miRNA-mediated regulation of clock gene expression in men and women with colorectal cancer and possible consequences for disease management	6
AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury	6
A recipe for a good clinical pulmonary surfactant	6
Reply: Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	6
The role of gut fungi in Clostridioides difficile infection	6
Elastase Reduces Background Autofluorescence in ALK Fluorescence In Situ Hybridization Assays for Lung Cancers	6
Charting new territory: The Plasmodium falciparum tRNA modification landscape	6
MicroRNA-based signature for diagnosis and prognosis of colorectal cancer using residuum of fecal immunochemical test	6
Chronobioethics: Symphony of biological clocks observed by 7-day/24-h ambulatory blood pressure monitoring and cardiovascular health	6
The respiratory impacts of air pollution in children: Global and domestic (Taiwan) situation	6
Editorial Board	5
High levels estradiol affect blastocyst implantation and post-implantation development directly in mice	5
Secreted proteins encoded by super enhancer-driven genes could be promising biomarkers for early detection of esophageal squamous cell carcinoma	5
Minimal invasive fixation following with radiotherapy for radiosensitive unstable metastatic spine	5
High-fat diet-induced increase in glucocorticoids contributes to adipogenesis in obese mice	5
Personalized medicine: From diagnostic to adaptive	5
Evaluation of recurrence risk in patients with papillary thyroid cancer through tumor-node-metastasis staging: A single-center observational study in Taiwan	5
Regenerative medicine for male infertility: A focus on stem cell niche injury models	5
LAMA5: A new pathogenic gene for non-syndromic cleft lip with or without cleft palate	5
Clinical and laboratory predictors for disease progression in patients with COVID-19: A multi-center cohort study	5
He protec but he also attac – Inflammasomes swinging the sword	5
After me, the deluge	5
A newly designed Flexible Hydrated-Hardening Bone Graft (FHBG) promotes bone regeneration and in vivo calvarial repair	5
Application of Solidago chilensis and laser improved the repair of burns in diabetic rats	5
Evaluation of clinical relevance and underlying pathology for hemodynamic compromise in acute small subcortical infarction using MRI-based neuroimaging markers	5
The role of excess charge mitigation in electromagnetic hygiene: An integrative review	5
Strategies to protect surfactant and enhance its activity	5
IRE1α-mediated endoplasmic reticulum stress response regulates oxidative damage in CYP4V2 deficient human retinal pigment epithelial cells	5
Unveiling the mycobiota: The fungal frontier of human health	5
Suppression of MGAT3 expression and the epithelial–mesenchymal transition of lung cancer cells by miR-188-5p	5
Dynamic monitoring of kidney injury status over 3 days in the intensive care unit as a sepsis phenotype associated with hospital mortality and hyperinflammation	5
Integrating comprehensive genomic profiling in the management of oncology patients: applications and challenges in Taiwan	5
Development and validation of a deep-learning-based pediatric early warning system: A single-center study	5
Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome i	5
Emerging mutation in SARS-CoV-2 spike: Widening distribution over time in different geographic areas	5
Study of polymethylmethacrylate/tricalcium silicate composite cement for orthopedic application	4
Y-chromosome genes associated with sertoli cell-only syndrome identified by array comparative genome hybridization	4
Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model	4
The ratio of remaining to expected small bowel length predicts enteral autonomy in pediatric patients with short bowel syndrome	4
Long non-coding RNA TTTY15 sponges miR-520a-3p to exacerbate neural apoptosis induced by cerebral ischemia/reperfusion via targeting IRF9 both in vivo and in vitro	4
Clinical feature, image findings and outcome of hepatosplenic candidiasis in patients with acute myeloid leukemia	4
Lipopeptides against COVID-19 RNA-dependent RNA polymerase using molecular docking	4
Increased risk of migraine among patients with hidradenitis suppurativa: A US multi-center cohort study	4
Acupressure reduces the severity of restless legs syndrome in hemodialysis patients: A cluster-randomized crossover pilot study	4
Immunogenicity of second booster-dose COVID-19 mRNA vaccine among older adults in Taiwan	4
Mpox: A narrative review on current knowledge	4
Physical attributes of salivary calcium particles and their interaction with gingival epithelium	4
The role and mechanism of CARD9 gene polymorphism in diseases	4
ECG-surv: A deep learning-based model to predict time to 1-year mortality from 12-lead electrocardiogram	4
The correlation of small fiber neuropathy with pain intensity and age in patients with Fabry's disease: A cross sectional study within a large Taiwanese family	4
Cytidine deaminase enhances liver cancer invasion by modulating epithelial-mesenchymal transition via NFκB signaling	4
Protein network analysis and functional enrichment via computational biotechnology unravel molecular and pathogenic mechanisms of kidney stone disease	4
Altered purinergic P2X7 and A2B receptors signaling limits macrophage-mediated host defense in schistosomiasis	4
Long noncoding RNA TUG1 promotes malignant progression of osteosarcoma by enhancing ZBTB7C expression	4