Biomedical Journal

Article	Citations
One day at a time	164
Living with tics: Nursing care of pediatric Tourette syndrome	120
Antrodia cinnamomea extract alleviates bleomycin-induced pulmonary fibrosis in mice by inhibiting the mTOR pathway	118
Polycystic kidney disease increases the stoke incidence in Taiwan: A retrospective population-based cohort study using National Health Insurance Database	60
Cell polarity regulators, multifunctional organizers of lymphocyte activation and function	58
Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study	57
The role of hypoxia-induced long noncoding RNAs (lncRNAs) in tumorigenesis and metastasis	47
Aptamer-functionalized liposomes for drug delivery	46
Roles of lncRNAs in the transcription regulation of HIV-1	42
Hyperammonemia induces microglial NLRP3 inflammasome activation via mitochondrial oxidative stress in hepatic encephalopathy	40
Bilateral lentiform and caudate nucleus lesions in a child with COVID-19: A case report	39
When it doesn't run in the blood(vessels) – events involved in vascular disorders	34
Editorial Board	34
Editorial Board	34
Editorial Board	34
Effects of electronic cigarette aerosol exposure on oral and systemic health	33
We refuse to die – T cells causing havoc	33
The establishment of a molecular diagnostic platform for mitochondrial diseases: From conventional to next-generation sequencing	32
m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle	31
High-throughput proteomics-guided biomarker discovery of hepatocellular carcinoma	30
Eligibility for live, interactive otolaryngology telemedicine: 19-Month experience before and during the COVID-19 pandemic in Taiwan	29
Middle cerebral artery velocity is associated with the severity of MRI brain injury in neonates received therapeutic hypothermia	28
Tools to measure membrane potential of neurons	28
Saliva as a diagnostic tool to measure polycyclic aromatic hydrocarbon exposure in dental patients exposed to intimate partner violence (IPV)	28
Role of SARS-CoV-2 and ACE2 variations in COVID-19	27

Lifestyle interventions to delay senescence	27
The effects of macronutrients metabolism on cellular and organismal aging	27
Implementation of fecal microbiota transplantation in a medical center for recurrent or refractory Clostridioides difficile infection and report of preliminary outcome	27
Comprehensive insight into the alterations in the gut microbiome and the intestinal barrier as a consequence of iron deficiency anaemia	25
Advancements, Challenges, and Future Prospects in Clinical Hyperpolarized Magnetic Resonance Imaging: A Comprehensive Review	24
Glycolytic metabolism and activation of Na+ pumping contribute to extracellular acidification in the central clock of the suprachiasmatic nucleus: Differential glucose sensitivity and utilization betw	24
Repeated administration of adipose-derived mesenchymal stem cells added on beneficial effects of empagliflozin on protecting renal function in diabetic kidney disease rat	23
The binding and specificity of chemokine binding proteins, through the lens of experiment and computation	23
Sterile inflammation and the NLRP3 inflammasome in cardiometabolic disease	22
Automatic and human level Graf's type identification for detecting developmental dysplasia of the hip	22
Long non-coding RNA HAGLROS facilitates the malignant phenotypes of NSCLC cells via repressing miR-100 and up-regulating SMARCA5	22
Discharge status validation of the Chang Gung Research database in Taiwan	21
“Mpox in MSM: Tackling stigma, minimizing risk factors, exploring pathogenesis, and treatment approaches”	21
Purinergic signaling: A new front-line determinant of resistance and susceptibility in leishmaniasis	20
Circadian rhythmicity and human health	20
Caffeic acid phenethyl ester inhibits the growth of bladder carcinoma cells by upregulating growth differentiation factor 15	19
Additional insights on SARS-CoV-2 spike protein variants and red blood cells biology	18
Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation	18
Using time-course as an essential factor to accurately predict sepsis-associated mortality among patients with suspected sepsis	18
A panel of miRNAs in the serum extracellular vesicles serve as novel diagnostic biomarkers for MASLD	18
Grafted bone remodeling following transcrestal sinus floor elevation: A cone-beam computed tomography study	18
Scaling the tips of the ALPS	17
Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype	17
Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head	17
Angular super-resolution in X-ray projection radiography using deep neural network: Implementation on rotational angiography	17
Endothelial activation, Cell-Cell Interactions, and Inflammatory Pathways in Postoperative Atrial Fibrillation Following Cardiac Surgery.	17
A finger in every pie – The versatility of chemokines	16
Nod-like receptors in inflammatory arthritis	16
Multifunctional nanozymes for disease diagnosis and therapy	16
Comparing transvenous coiling and transarterial embolization with Onyx/NBCA for cavernous sinus dural arteriovenous fistulas: A retrospective study in a single center	16
Intravascular Large B-cell lymphoma: A case series and review of literatures	16
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM)	16
Circ_0011385 knockdown inhibits cell proliferation, migration and invasion, whereas promotes cell apoptosis by regulating miR-330-3p/MYO6 axis in colorectal cancer	16
Low energy shock wave therapy attenuates mitochondrial dysfunction and improves bladder function in HCl induced cystitis in rats	16
Fecal miRNAs as potential biomarkers for early detection of colorectal cancer: An updated review	16
Hyperthermic intraperitoneal chemotherapy for recurrent epithelial ovarian cancer	16
Ancient wisdom and modern innovations: Methods of administering healing	15
Clinical validation of a saliva-based matrix metalloproteinase-1 rapid strip test for detection of oral cavity cancer	15
Extracellular vesicles in fetal-maternal immune tolerance	15
Significant decrease of a master regulator of genes (REST/NRSF) in high-grade squamous intraepithelial lesion and cervical cancer	15
Current efforts and challenges facing responses to Monkeypox in United Kingdom	15
Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes	15
Circ_0091579 exerts an oncogenic role in hepatocellular carcinoma via mediating miR-136-5p/TRIM27	15
Surgery for metastatic epidural spinal cord compression in thoracic spine, anterior or posterior approach?	15
Response to "letter to editor" from Nicolini et al. Regarding "Autonomic modulation and the risk of dementia in a middle-aged cohort: A 17-year follow-up study"	15
The incidence of resistance-associated variants to NS5A in HCV subtypes 1a and 1b in Taiwan	15
Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes	14
Clinical and functional characteristics of lung surgery-related vocal fold palsy	14
The epidemiology of invasive fungal infections in transplant recipients	14
Advancing cancer diagnosis and treatment: Integrating molecular biomarkers and emerging technologies	14

Strides toward a better understanding of the “Current efforts and challenges facing responses to Monkeypox in United Kingdom”	14
Joint effects of genomic markers and urinary methylation capacity associated with inorganic arsenic metabolism on the occurrence of cancers among residents in arseniasis-endemic areas: A cohort subset	14
SARS-CoV-2 variants – Evolution, spike protein, and vaccines	14
CAN008 prolongs overall survival in patients with newly diagnosed GBM characterized by high tumor mutational burden	14
Inherently imperfect, inherently evolving – The pursuit of precision through biomarkers	14
RASopathies: From germline mutations to somatic and multigenic diseases	13
Chronic low-dose REV-ERBs agonist SR9009 mitigates constant light-induced weight gain and insulin resistance via adipogenesis modulation	13
Phosphorylated α-synuclein in diluted human serum as a biomarker for Parkinson's disease	13
Targeted dexamethasone nano-prodrug for corneal neovascularization management	13
Mouth opening/breathing is common in sleep apnea and linked to more nocturnal water loss	13
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer	13
Pharmacological therapy for Tourette syndrome: What medicine can do and cannot do	13
Altered diffusivity of the subarachnoid cisterns in the rat brain following neurological disorders	13
Author reply to letter to the editor “Imaging abnormalities in pediatric neuro-COVID are more diverse than specified”	13
Utilizing nomograms to predict prevalent vertebral fracture risk: An analysis of dysmobility syndrome in a community-dwelling population	12
The best protection is early detection	12
Biological functions of extracellular vesicles from mammalian cells	12
Editorial Board	12
Phylogenetic characteristics of Non-SARS human coronavirus in southern Taiwan, 2012–2013	12
Macrophages of the Heart: Homeostasis and Disease	12
Clinical significance of incidental common bile duct dilatation in children: A 10-year single medical center experience	12
Editorial Board	12
Prognosis of chronic kidney disease in patients with non-alcoholic fatty liver disease: a Northeastern Taiwan community medicine research cohort	11
A CD33 frameshift variant is associated with neuromyelitis optica spectrum disorders	11
Typical and atypical enteropathogenic Escherichia coli in children with acute diarrhoea: Changing trend in East Delhi	11
Comparison of the outcome of emergency endotracheal intubation in the general ward, intensive care unit and emergency department	11
Blood oxygenation state in COVID-19 patients: Unexplored role of 2,3-bisphosphoglycerate	11
Glomerular disease classification and lesion identification by machine learning	11
A comprehensive overview of gastric cancer management from a surgical point of view	11
Factors associated with pyloric hypertrophy severity and post-operative feeding and nutritional recovery in infantile hypertrophic pyloric stenosis	11
A review for cell and particle tracking on microscopy images using algorithms and deep learning technologies	10
Practical applications of grounding to support health	10
Editorial Board	10
LncRNAs and asymmetric cell division: The epigenetic mechanisms	10
Editorial Board	10
Immunosenescence, gut dysbiosis, and chronic kidney disease: Interplay and implications for clinical management	10
Immunotherapy in older patients with cancer	10
COVID-19 vaccination uptake strongly predicts averted deaths of older people across Europe	10
Genomic Surveillance of SARS-CoV-2 in Taiwan: A Perspective on Evolutionary Data Interpretation and Sequencing Issues	10
Complementary effects of Orthosiphon stamineus standardized ethanolic extract and rosmarinic acid in combination with gemcitabine on pancreatic cancer	10
Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway	10
Infection control operations of a large hospital in Taiwan to prevent nosocomial outbreaks during COVID-19 pandemic	10
Negative regulatory NLRs mitigate inflammation via NF-κB pathway signaling in inflammatory bowel disease	10
Kinship analysis of type 2 diabetes mellitus familial aggregation in Taiwan	9
Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens	9
The role of endocytic trafficking in antigen T cell receptor activation	9
Real-world effectiveness of intravitreal dexamethasone implants - Comparison between eyes eligible and ineligible for clinical trials and their associated outcomes	9
Applications of three-dimensional imaging techniques in craniomaxillofacial surgery: A literature review	9
Editorial Board	9
Olesoxime protects against cisplatin-induced acute kidney injury by attenuating mitochondrial dysfunction	9
The next generation of healthcare ecosystem in the metaverse	9
Deep Learning Significantly Boosts CRT Response Prediction Using Synthetic Longitudinal Strain Data: Training on Synthetic Data and Testing on Real Patients	9
Different impacts of common risk factors associated with thrombocytopenia in patients with hepatitis B virus and hepatitis C virus infection	9
The 2022 nobel prize in physiology or medicine awarded for the decoding of the complete ancient human genome	9
Effects of light, electromagnetic fields and water on biological rhythms	9
Gut mycobiome in metabolic diseases: Mechanisms and clinical implication	9
Differential longitudinal effects of frequent sweetened food consumption at different exposure ages on child cognitive, language, and motor development	9
Techniques to evaluate surfactant activity for a personalized therapy of RDS neonates	9
MicroRNAs (−146a, −21 and −34a) are diagnostic and prognostic biomarkers for diabetic retinopathy	8
Role of purinoreceptors in the release of extracellular vesicles and consequences on immune response and cancer progression	8
An area of greatest vulnerability - Recent advances in kidney injury	8
Interferon-alpha and MxA inhibit BK polyomavirus replication by interaction with polyomavirus large T antigen	8
Editorial Board	8
Clinical studies on coronavirus disease 2019 (COVID-19) in the WHO registry network	8
The efficacies of non-bismuth containing quadruple therapies in the treatment of first-line anti-Helicobacter pylori across 4-year time interval with changing antibiotics resistance	8
The International Week of Surfactant Research: Increasing knowledge about surfactant and unexploited opportunities	8
Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	8
Neurotrophins BDNF and NT4/5 accelerate dental pulp stem cell migration	8
Small and mighty – microRNAs pulling the strings	8
c-MYC/METTL3/LINC01006 positive feedback loop promotes migration, invasion and proliferation of non-small cell lung cancer	8
SARS-CoV-2 pandemics: An update of CRISPR in diagnosis and host–virus interaction studies	8
Modification of brain waves and sleep parameters by Citrus reticulata Blanco. cv. Sai-Nam-Phueng essential oil	8
Novel approach by natural language processing for COVID-19 knowledge discovery	8
Genome-wide association study identifies DRAM1 associated with Tourette syndrome in Taiwan	8
Dilemmas in managing acute myocardial infarction during Covid-19 pandemic	8
Increased macrophage activation marker soluble CD163 is associated with graft dysfunction and metabolic derangements in renal transplant recipients	7
Human adenovirus infections in pediatric population - An update on clinico–pathologic correlation	7
Afterhyperpolarization potential modulated by local [K+]o in K+ diffusion-restricted extracellular space in the central clock of suprachiasmatic nucleus	7
Mutations in circulating tumor DNA detected in the postoperative period predict poor survival in patients with ovarian cancer	7
Basic implications on three pathways associated with SARS-CoV-2	7

Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients	7
Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress	7
Using A modified quickert procedure combined with prolapsed fat and preseptal orbicularis muscle removal to correct involutional lower eyelid entropion in Asians	7
Impact of fasting & ketogenic interventions on the NLRP3 inflammasome: A narrative review	7
Reading the epitranscriptome of the human malaria parasite	7
Palatal hybrid surgery for obstructive sleep apnea-state-of-the-art annotation of uvulopalatopharyngoplasty	7
Editorial Board	7
Mitochondrial Bioenergetics Deficiency in cisd-1 Mutants is Linked to AMPK-Mediated Lipid Metabolism	7
LncRNA OIP5-AS1 reduces renal epithelial cell apoptosis in cisplatin-induced AKI by regulating the miR-144-5p/PKM2 axis	7
Percentage genome change and chromosome 7q amplification predict sorafenib response in advanced hepatocellular carcinoma	7
Disposition of embryos from women who only produced morphologically poor embryos on day three	7
Hepatocyte nuclear factor 4 located in different developmental stages of Schistosoma japonicum and involved in important metabolic pathways	7
COVID-19 fatal outcomes: Role of the endothelial glycocalyx in both cell adhesion and migration	7
The respiratory impacts of air pollution in children: Global and domestic (Taiwan) situation	6
Effects of Rosa damascena on reproductive improvement, metabolic parameters, liver function and insulin-like growth factor-1 gene expression in estradiol valerate induced polycystic ovarian syndrome i	6
miRNA-mediated regulation of clock gene expression in men and women with colorectal cancer and possible consequences for disease management	6
Reply: Serum CA-125 and renal impairment in patients undergoing hyperthermic intraperitoneal chemotherapy	6
In-vitro and in-vivo functional observation studies to establish therapeutic potential of alpha-ketoglutarate against methotrexate induced liver injury	6
Would foot arch development in children characterize a body maturation process? A prospective longitudinal study	6
Inherited immunodeficiencies associated with proximal and distal defects in T cell receptor signaling and co-signaling	6
Postnatal intestinal mucosa and gut microbial composition develop hand in hand: A mouse study	6
Changing life styles for children with Tourette syndrome	6
The combination of low level laser therapy and efavirenz drastically reduces HIV infection in TZM-bl cells	6
A recipe for a good clinical pulmonary surfactant	6
This is not a pipe – But how harmful is electronic cigarette smoke	6
AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury	6
Charting new territory: The Plasmodium falciparum tRNA modification landscape	6
MicroRNA-based signature for diagnosis and prognosis of colorectal cancer using residuum of fecal immunochemical test	6
The role of gut fungi in Clostridioides difficile infection	6
Elastase Reduces Background Autofluorescence in ALK Fluorescence In Situ Hybridization Assays for Lung Cancers	6
Emerging mutation in SARS-CoV-2 spike: Widening distribution over time in different geographic areas	6
Chronobioethics: Symphony of biological clocks observed by 7-day/24-hour ambulatory blood pressure monitoring and cardiovascular health	6
Editorial Board	6
TP53 common variants and interaction with PPP1R13L and CD3EAP SNPs and lung cancer risk and smoking behavior in a Chinese population	6
Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis	6
Differential bicistronic gene translation mediated by the internal ribosome entry site element of encephalomyocarditis virus	6
Application of Solidago chilensis and laser improved the repair of burns in diabetic rats	6
Correlation of SALL1 with CEUS Parameters and Immune Escape in Thyroid Carcinoma	6
The correlation of small fiber neuropathy with pain intensity and age in patients with Fabry's disease: A cross sectional study within a large Taiwanese family	5
LAMA5: A new pathogenic gene for non-syndromic cleft lip with or without cleft palate	5
Clinical and laboratory predictors for disease progression in patients with COVID-19: A multi-center cohort study	5
Suppression of MGAT3 expression and the epithelial–mesenchymal transition of lung cancer cells by miR-188-5p	5
He protec but he also attac – Inflammasomes swinging the sword	5
High levels estradiol affect blastocyst implantation and post-implantation development directly in mice	5
Evaluation of recurrence risk in patients with papillary thyroid cancer through tumor-node-metastasis staging: A single-center observational study in Taiwan	5
Evaluation of clinical relevance and underlying pathology for hemodynamic compromise in acute small subcortical infarction using MRI-based neuroimaging markers	5
Personalized medicine: From diagnostic to adaptive	5
The effects of bone-substitute augmentation on treatment of osteoporotic intertrochanteric fractures	5
High-fat diet-induced increase in glucocorticoids contributes to adipogenesis in obese mice	5
Secreted proteins encoded by super enhancer-driven genes could be promising biomarkers for early detection of esophageal squamous cell carcinoma	5
Minimal invasive fixation following with radiotherapy for radiosensitive unstable metastatic spine	5
Modified ELISA for antibody avidity evaluation: The need for standardization	5
Strategies to protect surfactant and enhance its activity	5
Regenerative medicine for male infertility: A focus on stem cell niche injury models	5
Editorial Board	5
Prevention and treatment of COVID-19 infection by earthing	5
Dynamic monitoring of kidney injury status over 3 days in the intensive care unit as a sepsis phenotype associated with hospital mortality and hyperinflammation	5
Acupressure reduces the severity of restless legs syndrome in hemodialysis patients: A cluster-randomized crossover pilot study	5
Integrating comprehensive genomic profiling in the management of oncology patients: applications and challenges in Taiwan	5
A newly designed Flexible Hydrated-Hardening Bone Graft (FHBG) promotes bone regeneration and in vivo calvarial repair	5
Unveiling the mycobiota: The fungal frontier of human health	5
After me, the deluge	5
The role of excess charge mitigation in electromagnetic hygiene: An integrative review	5
Development and validation of a deep-learning-based pediatric early warning system: A single-center study	5
ECG-surv: A deep learning-based model to predict time to 1-year mortality from 12-lead electrocardiogram	4
Mpox: A narrative review on current knowledge	4
Msi2 enhances muscle dysfunction in a myotonic dystrophy type 1 mouse model	4
Long non-coding RNA TTTY15 sponges miR-520a-3p to exacerbate neural apoptosis induced by cerebral ischemia/reperfusion via targeting IRF9 both in vivo and in vitro	4
Therapeutic effect of bone marrow mesenchymal stem cells in a rat model of carbon tetrachloride induced liver fibrosis	4
Pediatric care for children with developmental coordination disorder, can we do better?	4
Application of extended reality in pediatric neurosurgery: A comprehensive review	4
Altered purinergic P2X7 and A2B receptors signaling limits macrophage-mediated host defense in schistosomiasis	4
Protein network analysis and functional enrichment via computational biotechnology unravel molecular and pathogenic mechanisms of kidney stone disease	4
Cytidine Deaminase Enhances Liver Cancer Invasion by Modulating Epithelial-Mesenchymal Transition via NFκB Signaling	4
Increased risk of migraine among patients with hidradenitis suppurativa: A US multi-center cohort study	4
Study of polymethylmethacrylate/tricalcium silicate composite cement for orthopedic application	4
Long noncoding RNA TUG1 promotes malignant progression of osteosarcoma by enhancing ZBTB7C expression	4
Influence of electromagnetic fields on the circadian rhythm: Implications for human health and disease	4
The role and mechanism of CARD9 gene polymorphism in diseases	4
Combined therapy with dapagliflozin and entresto offers an additional benefit on improving the heart function in rat after ischemia-reperfusion injury	4
Y-chromosome genes associated with sertoli cell-only syndrome identified by array comparative genome hybridization	4
Artificial neural network and logistic regression modelling to characterize COVID-19 infected patients in local areas of Iran	4
Physical attributes of salivary calcium particles and their interaction with gingival epithelium	4
Immunogenicity of second booster-dose COVID-19 mRNA vaccine among older adults in Taiwan	4
Lipopeptides against COVID-19 RNA-dependent RNA polymerase using molecular docking	4
A concerted effort combating hepatitis	4
Clinical feature, image findings and outcome of hepatosplenic candidiasis in patients with acute myeloid leukemia	4
Immunoinformatics prediction of potential B-cell and T-cell epitopes as effective vaccine candidates for eliciting immunogenic responses against Epstein–Barr virus	4
Gut microbiota and clinical response to immune checkpoint inhibitor therapy in patients with advanced cancer	4
The Ratio of Remaining to Expected Small Bowel Length Predicts Enteral Autonomy in Pediatric Patients with Short Bowel Syndrome	4