ERJ Open Research

Article	Citations
Dual CFTR modulator therapy efficacy in the real world: lessons for the future	256
Long-term incident severe outcomes in a prospective cohort of non-obese obstructive sleep apnoea patients free of comorbidities at inclusion	62
Supplementary oxygen efficacy for chronic pulmonary disorders and exertion desaturation	60
Williams–Campbell syndrome case series and discordant twins	45
The NEuroCOUGH Chronic Cough Registry: a protocol for a pan-European observational study	42
Diagnostic delay in bronchiectasis: an Italian perspective	37
Artificial intelligence augmentation raises questions about the future of bronchoscopy	37
Proteins associated with preserved ratio impaired spirometry	36
Moderate-to-severe ARDS: COVID-19 patients compared to influenza patients for ventilator parameters and mortality	36
High-frequency percussive ventilation in acute respiratory failure	34
Serotype distribution and coverage by pneumococcal vaccines in hospitalized adults with pneumococcal pneumonia in Germany	33
Role of bronchoscopy for respiratory involvement in granulomatosis with polyangiitis and microscopic polyangiitis	32
“Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts.” Michael R. Loebinger, Stefano Aliberti, Charles Haw	31
Global survey of physician testing practices for nontuberculous mycobacteria	30
Extracellular iron and the lung microbiome in smoking and COPD	30
Phase III AIRTIVITY™ study design – verducatib (BI 1291583) in people with bronchiectasis	30
Respiratory infections after elexacaftor/tezacaftor/ivacaftor treatment in people with cystic fibrosis: analysis of the European Cystic Fibrosis Society Patient Registry	29
Differential cardiopulmonary haemodynamic phenotypes in PASC-related exercise intolerance	29
Slow deep breathing reduces muscle sympathetic nerve activity and improves breathing efficiency in pulmonary hypertension	29
Myostatin/Smad2/Smad3 pathway define a differential clinical phenotype in COPD-associated sarcopenia	27
Anodal transcranial direct current stimulation over the right primary somatosensory cortex increases cough reflex sensitivity: a pilot randomised controlled crossover trial	27
The noninvasive ventilation outcomes score in patients requiring NIV for COPD exacerbation without prior evidence of airflow obstruction	27
Increased loop gain and upper airway collapsibility among smoking patients with obstructive sleep apnoea	27
Increasing airway obstruction through life following bronchopulmonary dysplasia: a meta-analysis	27
ROHHAD syndrome in an adult: presence of ZSCAN1 antibodies	26

Association of patient-reported outcome measures with lung function and mortality in fibrotic interstitial lung disease: a prospective cohort study	26
A comprehensive evaluation of murine and humanex vivocultured alveolar macrophages	26
Shape of the association between endotoxin in school dust and children's lung function	25
Prevalence and consequences of patient–ventilator interactions in a cohort of home-ventilated restrictive and neuromuscular patients: a multicentre study	25
Triple therapy in COPD: understanding the data	25
Circulating biomarkers in subjects with progressive pulmonary fibrosis: data from the INBUILD trial	24
Dendritic cells in the lung cavities of extensively drug-resistant tuberculosis patients exhibit altered frequency and phenotype	24
Achieving adherence to positive airway pressure in commercial drivers using an employer-mandated remote management programme	24
Improvements in small airway dysfunction and respiratory symptoms following Tezepelumab for severe asthma	24
Antitrypsin deficiency: still more to learn about the lung after 60 years	23
Prednisolone for COPD exacerbations: time for a rethink	23
Reflecting real-world patients with mesothelioma in research: an interim report of baseline characteristics from the ASSESS-meso cohort	23
Prevalence and types of treatable traits in bronchiectasis: a multicentre, cross-sectional study	23
Targeted DNase treatment of obstructive lung disease: a pilot randomised controlled trial	22
Corticosteroid therapy in fibrotic interstitial lung disease: a modified Delphi survey	22
Predicting clinical exacerbations using respiratory oscillometry during home telemonitoring of patients taking medium-/high-dose asthma treatment	22
The role of clamping before removal of a chest tube in post-surgical and pneumothorax patients using digital drainage systems: a noninferiority randomised trial	22
Diagnosis of pulmonary embolism in patients with haemoptysis: the POPEIHE study	21
A survey of UK respiratory specialists’ opinion on the management of chronic cough	21
ERS International Congress 2022: highlights from the Basic and Translational Science Assembly	21
Period and cohort effects: consequences on spirometric lung function in Norway during the 20th century	21
Comparison of two scores for short-term outcomes in patients with COPD exacerbation in the emergency department: the Ottawa COPD Risk Scale and the DECAF score	21
Rapid molecular detection of respiratory pathogens in patients with bronchiectasis	21
Increased delay to lung transplantation for women candidates: gender-based disparity matters in the lung transplant trajectory	21
Clinical impact of routine sleep assessment by peripheral arterial tonometry in patients with COPD	20
Shankh blowing in obstructive sleep apnoea: something special or a routine respiratory exercise?	20
Spirometry at different Latin American altitudes: a Global Lung Function Initiative project	20
Utility of rehabilitation prior to bronchoscopic lung volume reduction:post hocanalysis of the VENT trial	20
Effects of seasonality and treatment on COPD clinical outcomes: IMPACTpost hocanalysis	20
The long-term effects of insulin use in incident cystic fibrosis-related diabetes: a target trial emulated using longitudinal national registry data	20
Managing breathlessness for people with advanced respiratory disease	20
The impact of anti-eosinophilic therapy on exercise capacity and inspiratory muscle strength in patients with severe asthma	20
Supplements and medications for respiratory resilience against air pollution	20
Comorbidities reduce survival and quality of life in COPD with severe lung hyperinflation	19
Sarcopenia does not affect dyspnoea in patients with interstitial lung disease	19
Interstitial lung abnormalities: do symptoms matter?	19
Modifiable lifestyle risk factors for sarcoidosis: a nested case–control study	19
Socioeconomic inequalities in severe childhood asthma: results of a nationwide cohort	19
Associations of physical activity and quality of life in parapneumonic effusion patients	19
Impact of targeted pulmonary arterial hypertension therapies in severe pulmonary hypertension in chronic lung diseases	19
Detection of pulmonary hypertension in idiopathic pulmonary fibrosis using random forest models and automated measures of central computed tomography structures	19
e-Lung CT biomarkers are associated with outcomes in fibrotic interstitial lung diseases	19
Should all patients with COPD be treated with inhaled triple therapy?	18
An adjudication algorithm for respiratory-related hospitalisation in idiopathic pulmonary fibrosis	18
Oxygen saturation targets for children with respiratory distress: a systematic review	18
Still no room to breathe: insights on supine lung mechanics from oscillometry in COPD	18
A robust web-based tool to predict viral shedding in patients with Omicron SARS-CoV-2 variants	18
A worldwide look into long COVID-19 management: an END-COVID survey	18
Optimal treatment of the underlying aetiology is the most effective antimicrobial stewardship for chronic respiratory disease: a lesson learned from cystic fibrosis	18
Right ventricular–pulmonary arterial coupling predicts mortality in precapillary pulmonary hypertension	18

Chaotic breathing in post-COVID-19 breathlessness: a key feature of dysfunctional breathing can be characterised objectively by approximate entropy	18
Sleep and cardiometabolic comorbidities in the obstructive sleep apnoea–COPD overlap syndrome: data from the European Sleep Apnoea Database	17
Frailty and social, clinical, and CT imaging factors in COPD: a multicenter study	17
Effect of water- and land-based exercise on lung function in children with post-COVID-19 condition: secondary results from a randomised controlled trial	17
Navigating family dynamics and ethical considerations in genetic diagnosis of pulmonary arterial hypertension: insights from in-depth semi-structured interviews	17
Patient education and self-management in interstitial lung disease: why and what, now how?	17
Clinical validation of respiratory outcomes for a patch-based polysomnography system	17
Menthol inhalation relieves dyspnoea through the brain	17
Persistent tachypnoea of infancy and neuroendocrine cell hyperplasia of infancy: from systematic review to future directions	17
Incidence and predictors of self-reported pulmonary exacerbations in primary ciliary dyskinesia: an international prospective cohort study	17
Single-Cell RNA-seq Reveals Aberrant Airway Epithelial-Immune Cell Crosstalk In Pulmonary Fibrosis	17
Clinical impact and Healthcare Resource Utilization in Patients with Unexplained or Refractory Chronic Cough: A French National Population Study	17
Treatable traits and hospitalisations in asthma: the comorbidity conundrum	17
Home sleep studies in children with neurodisabilities: success rates and parental perception	17
Association of DPP-4 inhibitors with respiratory and cardiovascular complications in patients with COPD: a nationwide cohort study	16
Optimal follow-up duration for nonspecific pleuritis: how long is long enough?	16
Immunological biomarkers predict pulmonary and nodal, but not cardiac PET-assessed sarcoidosis activity	16
Real-world characteristics of “super-responders” to mepolizumab and benralizumab in severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis	16
Hospitalisation outcomes in pneumococcal-vaccinatedversus-unvaccinated patients with exacerbation of COPD: results from the HOPE COPD Study	16
Cell-free Tumor DNA in Bronchoalveolar Lavage- a proof of concept study	16
Long-term follow-up after bronchoscopic lung volume reduction valve treatment for emphysema	16
Add-on mepolizumab in patients with severe asthma on medium-dose inhaled corticosteroids	16
Key priorities to prevent avoidable asthma hospitalisations: insights from end-users	16
Pulmonary fibrosis in patients with autoimmune pulmonary alveolar proteinosis: a retrospective nationwide cohort study	16
Biomarkers of chronic airflow limitation and COPD identified by mass spectrometry	16
Safety and feasibility of ultrathin probe transbronchial lung cryobiopsy without balloon blockerviarobotic bronchoscopy in the evaluation of peripheral lung lesions: a retrospective pilot study	16
Deleterious effect of Pseudomonas aeruginosa on F508del-CFTR rescued by elexacaftor/tezacaftor/ivacaftor is clinical strain-dependent in patient-derived	15
α 1 -Antitrypsin deficiency and increased risk of atrial fibrillation in two large population-based cohorts	15
Risk factors, molecular analysis and treatment outcomes of amikacin-resistant Mycobacterium avium complex pulmonary disease	15
The Construct Validity of Real-World Digital Mobility Outcomes in People with Chronic Obstructive Pulmonary Disease	15
Deep-learning networks accurately detect pulmonary hypertension in patients with idiopathic pulmonary fibrosis	15
Sputum microbiome α-diversity is a key feature of the COPD frequent exacerbator phenotype	15
To burn or not to burn: similar effects of different types of prenatal tobacco exposure on infant lung function	15
Evaluation of a screening protocol for telomere biology disorders in individuals with interstitial lung disease undergoing lung transplant evaluation	15
Clinical assessment of balance and functional impairments in people with stable chronic obstructive pulmonary disease: a systematic review and meta-analysis	15
How to distinguish PPI-refractory from PPI-responsive patients in gastro-oesophageal reflux-induced chronic cough: post-reflux swallow induced peristaltic wave index and mean nocturnal baseline impeda	15
Demographic and clinical characteristics of patients with α1-antitrypsin deficiency genotypes PI*ZZ and PI*SZ in the Spanish registry of EARCO	15
Systemic Inflammation and Oxidative Stress in Bronchiectasis-Associated Sarcopenia	15
Developing a self-management package for pulmonary fibrosis: an international Delphi study	14
Persistence of a SARS-CoV-2 T-cell response in patients with long COVID and lung sequelae after COVID-19	14
Mepolizumab has clinical benefits including oral corticosteroid sparing irrespective of baseline EGPA characteristics	14
Intimal granulomatous angiitis in sarcoid pulmonary vasculitis: worth remembering	14
Severe pulmonary hypertension–interstitial lung disease presenting as right ventricular failure: stabilisation with intravenous prostacyclin and maintenance with inhaled prostacyclin	14
Changes in fatigue symptoms following an exercise-based rehabilitation programme for patients with long COVID	14
Plasma sphingolipids, lung function and COPD: the Cardiovascular Health Study	14
Pulmonary artery wedge pressure and left ventricular end-diastolic pressure during exercise in patients with dyspnoea	14
Priming mucosal pathogen-agnostic innate immunity with an intranasal TLR2/6 agonist in an aged population	14
Possible overdiagnosis of early-stage lung adenocarcinoma among never-smokers in Taiwan	14
“Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction”. Cristóbal Esteban, Nere Larrea, Amaia Aramburu, Javier Moraza, Leyre	14
Time to negative conversion and cardiopulmonary performance in athletes with COVID-19	14
Optimisation and application of a T-cell antigen-specific activation assay as diagnostic and treatment-monitoring tool for tuberculosis	14
COVID-19 in patients with pulmonary alveolar proteinosis: a European multicentre study	14
No effect of danazol treatment in patients with advanced idiopathic pulmonary fibrosis	14
Reply: Key role of dysregulated airway epithelium in response to respiratory viral infections in asthma	14
The feasibility of implementing clinical decision support system software in the outpatient assessment of breathlessness: Cardio-LungHealth and Everton in the Community	14
Phase I dose-escalation study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of an inhaled recombinant human ACE2	13
The effect of electrical stimulation of the upper airway dilator muscles on blood pressure in healthy volunteers and patients with obstructive sleep apnoea: a systematic review and meta-analysis	13
Increased bronchiectasis risk and related risk factors in inflammatory bowel disease: a 10-year Korean national cohort study	13
Rapid real-world implementation of pulmonary telerehabilitation: good fortune or COVID-19 luck?	13
Acknowledging the syndemic: a real-life cohort study of major adverse cardiovascular events in COPD	13
Association of German Bronchiectasis Registry Participation With Disease Course	13
The impact of the COVID-19 pandemic on pleural infection incidence: a UK multicentre retrospective analysis	13
Acute effects of low-dose bisoprolol on lung function and blood pressure in COPD patients	13
Redefining chronic cough as a disease: why patient registries matter	13
Shared genetic risk factors: implications for treatment of idiopathic pulmonary fibrosis and systemic hypertension	13
Upper-lobe CT imaging features improve prediction of lung function decline in COPD	13
A focus group study about healthcare professionals’ perspectives on patient education in pulmonary rehabilitation	13
Benefit−risk assessment of brensocatib for treatment of non-cystic fibrosis bronchiectasis	13
ERS Congress 2024: highlights from the Basic and Translational Sciences Assembly	13
“Breathlessness stops me doing everything”: exploring the impact of chronic breathlessness due to advanced respiratory disease and exacerbating factors – a qualitative study	13
Untargeted metabolomic analysis reveals different metabolites associated with response to mepolizumab and omalizumab in asthma	13
Infant lung function: criteria for selecting tidal flow–volume loops	13
Cardiac dysfunction during exercise in young adults with bronchopulmonary dysplasia	13
Shorter walk test durations to detect ambulatory oxygen desaturation in interstitial lung disease: an observational cohort study	13
Next-generation sequencing reveals genetic heterogeneity and resistance mechanisms in patients withEGFR-mutated non-small cell lung cancer treated with afatinib	13
Predictors of mortality and hospitalised exacerbations in obstructive airway diseases	13
Effects of exercise and a lifestyle app on sleep disordered breathing, physical health and quality of life	12
Airway Smooth Muscle in Asthma: Insights from a Transcriptomic Meta-analysis	12
Beyond spirometry: understanding COPD origins to support a new diagnostic approach	12
Arterial remodelling in smokers and in patients with small airway disease and COPD: implications for lung physiology and early origins of pulmonary hypertension	12

ERS International Congress 2022: highlights from the Interstitial Lung Diseases Assembly	12
ERS Congress 2024: highlights from the Clinical Techniques, Imaging and Endoscopy Assembly	12
Acute and 14-Day Effects of Tiotropium/Olodaterol on Cardiopulmonary Function in COPD	12
Dupilumab-associated hypereosinophilia in severe asthma	12
Compartment-specific protein interactions in beryllium lung disease	12
Predictors of invasive mechanical ventilation use in patients with acute decompensated pulmonary hypertension admitted to the intensive care unit	12
Diffuse panniculitis in a teenage male with ZZ α1-antitrypsin deficiency	12
An exploration of clinically meaningful definitions of cough bouts	12
Patients at risk of nontuberculous mycobacterial pulmonary disease who need testing evaluated using a modified Delphi process by European experts	12
It is time to end our love affair with short-acting β2-agonists in asthma? Yes	12
Artificial intelligence and radiomics in drug-induced interstitial lung disease	12
Biomarkers of type 2 inflammation as predictors of response to biologics for severe eosinophilic asthma	12
Upper-limb intervalversusconstant-load exercise in patients with COPD: a physiological crossover study	12
Systemic pro-inflammatory response following bronchoscopic lung volume reduction using endobronchial valves	12
Circulating biomarkers and progression of idiopathic pulmonary fibrosis: data from the INMARK trial	12
Spirometry interpretation in primary care: is there a role for artificial intelligence?	11
Early benefit of mepolizumab on small airways in severe asthma: insights from the IMPOSE study	11
Locus of control and breathlessness: a cross-sectional analysis of 28 730 people	11
Telemonitoring for the follow-up of home noninvasive ventilation: a promising future with ongoing challenges	11
Insights from the INSIGHTS-ILD Registry: real-world heterogeneity in treatment patterns for patients with fibrotic interstitial lung disease	11
Circadian variability in breath volatiles is affected by the timing of inhaled corticosteroids in asthma	11
Methicillin-resistant Staphylococcus aureus and pulmonary outcome in people with cystic fibrosis: a European Cystic Fibrosis Patient Registry data analysis	11
“A pulmonary rehabilitation shared decision-making intervention for patients living with COPD: PReSent: protocol for a feasibility study”. Amy C. Barradell, Linzy Houchen-Wolloff, Noelle Robertson, Hi	11
Gene expression profile of epithelial–mesenchymal transition in tumours of patients with nonsmall cell lung cancer: the influence of COPD	11
Efficacy of interventions to alter measures of fat-free mass in people with COPD: a systematic review and meta-analysis	11
Adverse perception of cough in patients with severe asthma: a discrete choice experiment	11
Longitudinal change in ultrasound-derived rectus femoris cross-sectional area in COPD	11
Factors most strongly associated with breathlessness in a population aged 50–64 years	11
Home is where spirometry should be: enhancing care for individuals with pulmonary fibrosis	11
Influence of age in the assessment of therapeutic response in patients with pulmonary arterial hypertension	11
Comparative Analysis of FEV 1 Expressions: Association with All-Cause Mortality	11
The effect of exacerbations on lung density in α1-antitrypsin deficiency	11
Physical capacity and inactivity in obstructive airway diseases: a “can do, do do” analysis	11
Ciliary dyskinesia in severe asthma is not affected by chronic mucus hypersecretion	11
Living with chronic cough: experiences, burden and management in interstitial lung disease – a mixed methods study	11
Respiratory symptoms and their determinants in the general Spanish population: changes over 20 years	11
Normal values of respiratory oscillometry in South African children and adolescents	11
Obstructive sleep apnoea-related respiratory events and desaturation severity are associated with the cardiac response	11
The role of the ADRB2 Thr164Ile variant in lung function determination, plasma proteome variability and other phenotypes in UK Biobank	11
Response to endobronchial valve treatment: it's all about the target lobe	11
Feasibility of using continuous positive airway pressureviathe LeVe CPAP System among children with acute hypoxaemic respiratory failure at Mengo Hospital, Kampala, Uganda: a mixed-methods stud	11
Characteristics and management of asthma from China Asthma Data Registry Project (CHART)	11
The association of weather conditions with day-to-day variability in physical activity in patients with COPD	11
Lung disease in never-smokers with severe α 1 -antitrypsin deficiency: the EARCO Registry	11
Inhaled nitric oxide for the treatment of COVID-19: an open-label, parallel, randomised controlled trial	11
ERS International Congress 2023: highlights from the Respiratory Intensive Care Assembly	10
NKX2.1mutation revealed by a lymphoid interstitial pneumonia in an adult with rheumatoid arthritis	10
Conservation of gene expression patterns between the amniotic and nasal epithelium at birth	10
A novel method to assess airway eosinophilia using sputum plugs	10
Effects of acetazolamide on sleep disordered breathing in pulmonary vascular disease: a randomised controlled trial	10
Laboratory and free-living gait performance in adults with COPD and healthy controls	10
Inhaler Mastery and Retention after Stepwise Training in Cognitively Impaired Older COPD	10
Natural variability of lung function in primary ciliary dyskinesia: longitudinal analysis from the PROVALF-PCD cohort	10
Activation of STAT3 in the COPD airway epithelium	10
Exercise responses and mental health symptoms in COVID-19 survivors with dyspnoea	10
Peeping at COPD through the keyhole: time to broaden the view to the complexity of the disease by the heterogeneity of symptoms	10
Eradication of early MRSA infection in cystic fibrosis: a novel study design for the STAR-ter trial	10
Importance of sputum and computed tomography assessments of airway neutrophil inflammation and mucus plugging in bronchiectasis management	10
Validation and cross-cultural insights of the French translation of the Severe Asthma Questionnaire	10
Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial	10
Post-pandemic seasonal dynamics of hospitalised COPD exacerbations and aetiologies in the COPD population	10
OSA symptom subtypes and hypoxic burden independently predict distinct cardiovascular outcomes	10
The Palestinian primary ciliary dyskinesia population: first results of the diagnostic and genetic spectrum	10
Reduced Cough Severity and Improved Confidence in Self-Management Following Completion of a Vi rtual P hys	10
Is it time for a simplified method to evaluate airway eosinophilia?	10
Persistence of lung hyperinflation and small airway dysfunction in school-aged children with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor: results from the real-world MODUL-CF study	10
Poor performance of paired tests of latent tuberculosis in highly immune-compromised individuals exposed to multidrug-resistant tuberculosis: time for new diagnostic markers	10
Assessment of factors and interventions towards therapeutic adherence among persons with non-cystic fibrosis bronchiectasis	10
Exercise intolerance in post-coronavirus disease 2019 survivors after hospitalisation	10
End-tidal carbon dioxide tension is a reliable surrogate of arterial carbon dioxide tension across different oxygen, carbon dioxide and barometric pressures	10
Beyond type 2 asthma biomarkers: risk stratification for NSAID-exacerbated respiratory disease	10
Chronic noninvasive ventilation in COPD: towards the identification of a responder phenotype	10
Clinical utility of sputum cytology in severe asthma: insights from a specialist centre	10
Risk factors and interventions for developing recurrent pneumonia in older adults	10
Artificial intelligence improves bronchoscopy performance: a randomised crossover trial	10
Pulmonary Hypertension and Measurement of Exercise Capacity Remotely: Evaluation of the 1-min Sit-to-Stand Test (PERSPIRE) – a cohort study	10
Measuring spirometry in a lung cancer screening cohort highlights possible underdiagnosis and misdiagnosis of COPD	10
Immunoprofiling bronchoalveolar lavage cells reveals multifaceted smoking-associated immune dysfunction	10
Predicting outcomes after hospitalisation for COPD exacerbation using machine learning	9
Periostin and airway mucus plugs in non-asthmatic former smokers with and without COPD	9
Endobronchial cryobiopsy may shorten the time to cancer diagnosis: a retrospective study	9
Do biologics improve health outcomes in children with severe asthma? – a Cohort study	9
Efficacy of morphine on cough in patients with repeat expansions of RFC1 and refractory chronic cough	9
The effects of dual IQOS and cigarette smoke exposure on airway epithelial cells: implications for lung health and respiratory disease pathogenesis	9
Telemedicine and virtual respiratory care in the era of COVID-19	9
A comparison of pulmonary capillary blood volume and membrane diffusing capacity assessed via two pulmonary diffusing capacity approaches	9
Clinical significance of respiratory bacteria and mycobacteria isolates in adult bronchiectasis in Taiwan	9
Bronchiectasis associated with ulcerative colitis relapse after lung transplantation: a case report	9
Reference equations for quadriceps strength, endurance and power: a multicentre study	9
Utility of adding oesophageal to endobronchial endosonography when staging lung cancer: a randomised trial	9
Exploring lung cavity access to endobronchial valve in chronic pulmonary aspergillosis and nontuberculosis mycobacterial diseases, a radiological feasibility study	9
Hypercapnia is not excluded by normoxia in neuromuscular disease patients: implications for oximetry	9
Characteristics of severe disease in GL-ILD: a retrospective cohort study	9
Mirror, mirror on the wall: is CompEx the fairest endpoint of all?	9
Identification of two distinct molecular endotypes in cough-variant asthma based on sputum transcriptomics and clinical pathophysiological features	9