OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Molecular Biosciences is 52. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Implementation of a combined bioinformatics and experimental approach to address lncRNA mechanism of action: The example of NRIR	222
Machine learning-enhanced insights into sphingolipid-based prognostication: revealing the immunological landscape and predictive proficiency for immunomotherapy and chemotherapy responses in pancreati	208
Editorial: In celebration of women in science: RNA networks and biology	196
Editorial: Analytical devices based on immobilized macromolecules for structural and activity/affinity studies in drug discovery	177
Editorial: Interactions of nanoparticles with and within living organisms—What can we learn to improve efficacy of nanomedicine?	151
Melasolv™: a potential preventive and depigmenting agent for the senescence of melanocytes	144
Preparation of RNAs with non-canonical 5′ ends using novel di- and trinucleotide reagents for co-transcriptional capping	125
The endothelial layer formation in the presence of AuNPs/CdSe/TaNPs-loaded PLCL/PVP-based electrospun nanofibers	123
Editorial: Novel approaches aiming to overcome current nanomedicine limitations	115
Editorial: Ironome: a still untapped frontier	114
Editorial: In honor of Dr. Bruce Ames: innovations in mutagenesis and DNA repair	113
Moving HER2-low breast cancer predictive and prognostic data from clinical trials into the real world	105
A novel pyroptosis-regulated gene signature for predicting prognosis and immunotherapy response in hepatocellular carcinoma	104
Cardiolipin occupancy profiles of YidC paralogs reveal the significance of respective TM2 helix residues in determining paralog-specific phenotypes	104
Corrigendum: Evaluation of PIK3CA mutations in advanced ER+/HER2-breast cancer in Portugal – U-PIK Project	103
Opto-APC: Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions	101
Modeling of pneumococcal serogroup 10 capsular polysaccharide molecular conformations provides insight into epitopes and observed cross-reactivity	98
Shared pathobiology identifies AMPK as a therapeutic target for obesity and autosomal dominant polycystic kidney disease	89
Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples	83
Sex-dependent alterations of salivary microbiome in Parkinson’s disease: associations with motor and non-motor clinical phenotypes	82
ELOVL5 and IGFBP6 genes modulate sensitivity of breast cancer cells to ferroptosis	78
RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study	77
Deepening insights into cholinergic agents for intraocular pressure reduction: systems genetics, molecular modeling, and in vivo perspectives	75
Creatinine, leucine, and tetrahydrocorticosterone emerge as potential biomarkers for the diagnosis of sarcopenic osteoarthritis in middle-aged and elderly individuals: a cross-sectional exploratory st	74
Identification of key genes related to growth of largemouth bass (Micropterus salmoides) based on comprehensive transcriptome analysis	73

Metabolome combined with gut microbiome revealed the lipid-lowering mechanism of Xuezhiping capsule on hyperlipidemic hamster induced by high fat diet	72
Revealing the pharmacological effect and mechanism of darutoside on gouty arthritis by liquid chromatography/mass spectrometry and metabolomics	71
The chemistry of gut microbiome-derived lipopolysaccharides impacts on the occurrence of food allergy in the pediatric age	69
From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data	67
Keeping up with the condensates: The retention, gain, and loss of nuclear membrane-less organelles	67
Serum bile acid metabolic profiles in polycystic ovary syndrome: insights from targeted metabolomics and correlation with embryonic parameters	67
Investigating potential targets of Wulingsan in diabetic nephropathy through network pharmacology and experimental validation	66
Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implications for blood-brain barrier	65
Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis	65
A potential allosteric inhibitor of SARS-CoV-2 main protease (Mpro) identified through metastable state analysis	63
Integrating network analysis with differential expression to uncover therapeutic and prognostic biomarkers in esophageal squamous cell carcinoma	63
Identification of novel gene signatures and immune cell infiltration in intervertebral disc degeneration using bioinformatics analysis	63
Identification of diagnostic hub genes related to energy metabolism in idiopathic pulmonary fibrosis	61
Autosomal dominant and autosomal recessive polycystic kidney disease: hypertension and secondary cardiovascular effect in children	61
Zinc phthalocyanine loaded- antibody functionalized nanoparticles enhance photodynamic therapy in monolayer (2-D) and multicellular tumour spheroid (3-D) cell cultures	60
Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells	60
Detection of mutations: from Ames test to duplex sequencing	59
Application of PCR-based approaches for evaluation of cell-free DNA fragmentation in colorectal cancer	59
Integrated transcriptomic profiling reveals oncogenic pathways and chimeric transcripts in equine sarcoid lesions with predominant BPV1 detection	58
A systematic review reveals conflicting evidence for the prevalence of antibodies against the sialic acid ‘xenoautoantigen’ Neu5Gc in humans and the need for a standardised approach to quantification	58
A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors	56
Type-2 diabetes epigenetic biomarkers: present status and future directions for global and Indigenous health	56
FABP4 in obesity-associated carcinogenesis: Novel insights into mechanisms and therapeutic implications	55
Mechanosensory encoding dysfunction emerges from cancer-chemotherapy interaction	55
Comparative analysis of tissue-specific anticancer peptide prediction models: ACP-Boost framework	54
Interaction of gut microbiota with the tumor microenvironment: A new strategy for antitumor treatment and traditional Chinese medicine in colorectal cancer	53
The application of exosomes in the treatment of triple-negative breast cancer	53
Bioactive chemical composition and pharmacological insights into Salvia species	52