Frontiers in Cell and Developmental Biology

Papers
(The TQCC of Frontiers in Cell and Developmental Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)
ArticleCitations
Methods for automating the analysis of live-cell single-molecule FRET data372
The orobasal organ (of Ackerknecht) is present in prenatal mice177
General Commentary: Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods161
Overexpression of long noncoding RNA 4933425B07Rik leads to renal hypoplasia by inactivating Wnt/β-catenin signaling pathway154
Editorial: The self-renewal and reprogramming of cancer stem cells and their crosstalk with the immune microenvironment127
Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos126
Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology117
Editorial: Development, metabolism, senescence and mechanotransduction of bone110
Editorial: Immunological imbalance: What is its role in intervertebral disc degeneration?110
Chronic electrical stimulation with a peripheral suprachoroidal retinal implant: a preclinical safety study of neuroprotective stimulation109
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome108
Editorial: DNA damage response in the context of chromatin106
Editorial: Post-transcriptional regulation of embryonic and adult myogenesis100
A novel GCaMP6f-RCS rat model for studying electrical stimulation in the degenerated retina100
Editorial: WT1 in Development and Disease100
Targeting N-type calcium channels in young-onset of some neurological diseases98
Editorial: The contribution of autophagy to neuronal metabolism98
Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling95
Regulation of the microprocessor by post-translational modifications92
Real-world database evaluation of drug-associated vitreous opacities and machine learning for clinical interpretability90
Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway90
CausalFormer-HMC: a hybrid memory-driven transformer with causal reasoning and counterfactual explainability for leukemia diagnosis89
Integrative analysis of EMT-driving genes identifies a prognostic signature and GJB2 as a potential biomarker in glioblastoma89
TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure87
Fertility preservation in male cancer patients. Counseling and reproductive outcomes87
Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma85
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue85
Effectiveness comparison of pembrolizumab versus other immune checkpoint inhibitors in neoadjuvant chemoimmunotherapy for esophageal squamous cell carcinoma84
PARP9 drives the malignant progression of pancreatic cancer cells by regulating apoptosis, DNA damage, and multidrug efflux systems84
Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia82
Decoding RNF20: an epigenetic modifier and beyond82
Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification80
ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled?78
Retraction: MiR-221/222 ameliorates deoxynivalenol-induced apoptosis and proliferation inhibition in intestinal epithelial cells by targeting PTEN78
Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration78
Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis77
Mitoregulin, a tiny protein at the crossroads of mitochondrial functioning, stress, and disease77
The diverse roles of macrophages in metabolic inflammation and its resolution77
Editorial: Ethological dynamics in diorama environments76
The regulation of transcription elongation in embryonic stem cells76
The role of ANLN in malignant tumors: pathogenesis, treatment resistance and targeted strategies75
Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes75
Corrigendum: Single-cell RNA sequencing reveals the role of phosphorylation-related genes in hepatocellular carcinoma stem cells73
Correction: ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer73
Corrigendum: Global research trends of ferroptosis: a rapidly evolving field with enormous potential73
Ferroptosis and Alzheimer’s disease: unraveling the molecular mechanisms and therapeutic opportunities72
Krill oil treatment ameliorates lipid metabolism imbalance in chronic unpredicted mild stress-induced depression-like behavior in mice72
New strategies for neuro protection in glaucoma71
Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos71
Integrated genomic analysis identifies novel low-frequency cis-regulatory variant rs2279658 associated with VSD risk in Chinese children70
Editorial: Biophysical target engagement assays in chemical biology and pharmacological research70
Treatment of patients with metastatic epidural spinal cord compression using an enhanced recovery after surgery program69
Role of UDP-glucose ceramide glucosyltransferase in venous malformation69
Coupling of stemness maintenance with cell cycle control in stem cells69
Effects of Transcription-Dependent Physical Perturbations on the Chromosome Dynamics in Living Cells66
Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease65
Morinda officinalis oligosaccharides attenuate mitochondria-associated ferroptosis via the NOX4/mitoGPX4 pathway in myocardial ischemia‒reperfusion injury65
The tendon interfascicular basement membrane provides a vascular niche for CD146+ cell subpopulations65
Modeling the spatiotemporal properties of crosstalk between RyR-mediated and IP3R-mediated local Ca2+ release65
Single-cell RNA sequencing reveals cell subpopulations in the tumor microenvironment contributing to hepatocellular carcinoma65
The Mkx- TGF-β pathway induced the development of the myodural bridge complex in SD rats64
Quantitative analysis of Robertsonian chromosomes inherited by descendants from multiple Rb heterozygotes of Mus m. Domesticus64
Prolactin drives cortical neuron maturation and dendritic development during murine embryonic stem cell differentiation63
Editorial: Personalized medicine for neuromuscular disorders62
Mitochondrial epigenetic mechanisms in cancer: an updated overview62
G-patch proteins: important regulators of pre-mRNA splicing and ribosome biogenesis61
From organelles to therapy: rethinking combined hepatocellular-cholangiocarcinoma61
Enhancement of chemotherapeutic efficacy via non-canonical autophagy induced by Olea europaea in human model of lung adenocarcinoma cells (A549)60
Kinase PLK1 regulates the disassembly of the lateral elements and the assembly of the inner centromere during the diakinesis/metaphase I transition in male mouse meiosis60
BDNF-loaded chitosan-based mimetic mussel polymer conduits for repair of peripheral nerve injury60
Roles of RNA-binding proteins in macrophage function regulation and immunotherapy59
Paternal impact on the developmental programming of sexual dimorphism59
Mechano-biochemical marine stimulation of inversion, gastrulation, and endomesoderm specification in multicellular Eukaryota58
The crosstalk between MYC and mTORC1 during osteoclastogenesis58
Impact of WTAP in small HCC and paired adjacent non-neoplastic liver tissue on recurrence: A cohort study with external extension analysis58
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations58
Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value57
Crossover interference mechanism: New lessons from plants57
Regeneration of the dermal skeleton and wound epidermis formation depend on BMP signaling in the caudal fin of platyfish57
Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods57
Ultra-short laser processing of 3D bioceramic, porous scaffolds designed by freeze foaming method for orthopedic applications56
A review of cell death pathways in hemorrhagic stroke56
Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling55
Synergy between a cytoplasmic vWFA/VIT protein and a WD40-repeat F-box protein controls development in Dictyostelium54
Epigenetic and transcriptomic alterations in the ClC-3-deficient mice consuming a normal diet54
Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis53
Perspectives on the α5 nicotinic acetylcholine receptor in lung cancer progression53
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation53
Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway53
Disruption of fos causes craniofacial anomalies in developing zebrafish52
JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex52
Interferon-primed immune landscapes predict immune-related adverse events during immune checkpoint inhibitor therapy52
Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy52
Advances in Traditional Chinese Medicine for chronic obstructive pulmonary disease through multi-omics approaches51
N6-methyladenosine RNA methylation: From regulatory mechanisms to potential clinical applications51
mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila51
H19 and IGF2 imprinting from embryogenesis to oncogenesis51
Palmitoyltransferase DHHC7 mediates protein palmitoylation and is essential for sperm function through the modulation of [Ca2+]i and ROS signaling50
In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers50
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems49
Weibel-Palade bodies – secretory organelles at the interface of inflammation and hemostasis49
Cyclodextrin nanoparticles for diagnosis and potential cancer therapy: A systematic review49
Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation48
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery48
B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions48
GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway47
Stage- and compartment-specific remodeling of autophagy and selective mitophagy in glaucoma: from aqueous outflow dysfunction to retinal ganglion cell neurodegeneration47
A FOS/NFKB1-associated Hofbauer cell subset mediates placental niche dysregulation in early-onset fetal growth restriction46
Role of microglia in diabetic neuropathic pain46
Of mice and men: Pinpointing species differences in adipose tissue biology46
Metabolic biomarkers of neonatal sepsis: identification using metabolomics combined with machine learning46
Development, regeneration, and physiological expansion of functional β-cells: Cellular sources and regulators46
From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization46
Tumor resident microbiota and response to therapies: An insight on tissue bacterial microbiota46
Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles46
PLANAtools—An interactive gene expression repository for the planarian Schmidtea mediterranea46
Mitochondrial DNA abnormalities and metabolic syndrome46
Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus46
From iPSC to manufactured iNK cells using CombiCult® screening platform46
Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins45
The gut–brain axis: mechanisms linking intestinal dysbiosis with stroke45
Control of mitochondrial dynamics and apoptotic pathways by peroxisomes45
Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons45
MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis45
Liver X Receptors (LXRs) in cancer-an Eagle’s view on molecular insights and therapeutic opportunities45
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles45
Targeted Plasmalogen Supplementation: Effects on Blood Plasmalogens, Oxidative Stress Biomarkers, Cognition, and Mobility in Cognitively Impaired Persons44
Engineered exosomes: a promising design platform for overcoming cancer therapy resistance44
Mechanisms of CAR T cell exhaustion and current counteraction strategies44
Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids44
Resolution of inflammation during rheumatoid arthritis44
Comparison of plasma- and saliva-derived exosomal miRNA profiles reveals diagnostic potential in head and neck cancer44
Obesity and sudden cardiac death: Prevalence, pathogenesis, prevention and intervention44
EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation44
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis44
Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke43
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids43
Iron-mediated oxidative stress induces PD-L1 expression via activation of c-Myc in lung adenocarcinoma43
DNA repair genes play a variety of roles in the development of fish embryos43
Emerging Roles of Long Noncoding RNAs in Breast Cancer Epigenetics and Epitranscriptomics43
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility43
Caloric restriction induced epigenetic effects on aging43
Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental insufficiency during pregnancy43
Involvement of role of HMGB1-NLRP3 pathway in systemic disorders42
Structural regulation and dynamic behaviour of organelles during plant meiosis42
Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro42
Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma42
Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging42
The role of retinal Müller cells in diabetic retinopathy and related therapeutic advances41
Systemic inflammatory regulators and risk of acute-on-chronic liver failure: A bidirectional mendelian-randomization study41
Regulation of insulin secretion by the post-translational modifications41
Autophagy, innate immunity, and cardiac disease41
Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss41
Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells41
The roles of lncRNA functions and regulatory mechanisms in the diagnosis and treatment of hepatocellular carcinoma41
Construction of a prognostic assessment model for colon cancer patients based on immune-related genes and exploration of related immune characteristics41
MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives41
Getting cells into shape by calcium-dependent actin cross-linking proteins41
Evaluation of the effect of GSK-3β on liver cancer based on the PI3K/AKT pathway41
The long-term neurodevelopmental outcomes of febrile seizures and underlying mechanisms40
Deciphering the triad of endothelial glycocalyx, von Willebrand Factor, and P-selectin in inflammation-induced coagulation40
Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells40
Quercetin protects porcine oocytes from in vitro aging by reducing oxidative stress and maintaining the mitochondrial functions40
Research progress in deep learning-based fundus image analysis for the diagnosis and prediction of hypertension-related diseases40
Mathematical modeling and application of IL-1β/TNF signaling pathway in regulating chondrocyte apoptosis40
Interactions between glioblastoma and myeloid cells40
GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria40
Quercetin improves and protects Calu-3 airway epithelial barrier function40
Taste receptors affect male reproduction by influencing steroid synthesis39
Exploring the protective mechanisms of the yunpi jiedu tongluo qushi decoction on methotrexate-induced reproductive damage in male rats based on Nrf2/HO-1 signaling pathway39
Role of exosomes and exosomal microRNA in muscle–Kidney crosstalk in chronic kidney disease39
Integrative single-cell and bulk RNA sequencing unravels the role of ACTN1 in promoting lung cancer with brain metastasis and epidermal growth factor receptor-tyrosine kinase inhibitor resistance39
SIRT3/6/7: promising therapeutic targets for pulmonary fibrosis39
NOC1 is a direct MYC target, and its protein interactome dissects its activity in controlling nucleolar function39
Two distinct forms of human BLT2: long-form and short-form BLT239
Surface decorated quantum dots: Synthesis, properties and role in herbal therapy39
Drosophila: a Tale of regeneration with MYC39
Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling39
Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics39
Correction: Polychlorinated biphenyls and breast cancer evidence, mechanisms, and risk management39
Axonal regeneration and innervation ratio following supercharged end-to-side nerve transfer39
Different seminal ejaculated fractions in artificial insemination condition the protein cargo of oviductal and uterine extracellular vesicles in pig38
MicroRNA: role in macrophage polarisation and colorectal cancer pathogenesis38
MicroRNA target homeobox messenger RNA in HIV induced hematopoietic inhibition38
Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium38
Long-term efficacy and safety of sirolimus for retinal astrocytic hamartoma associated with tuberous sclerosis complex38
Augmenting mesenchymal stem cell therapy for osteoarthritis via inflammatory priming: a comparative study on mesenchymal stem cells derived from various perinatal tissue sources38
A novel chemical genetic approach reveals paralog-specific role of ERK1/2 in mouse embryonic stem cell fate control38
Editorial: Current methods for detecting and diagnosing stem cell pathogenesis: a focus on translational interventions in the contemporary disease and technology landscape38
Chromatin remodeling complexes: architects influencing breast cancer progression38
LncRNA model predicts liver cancer drug resistance and validate in vitro experiments38
Editorial: Mechanisms of hox-driven patterning and morphogenesis38
Nanotopographic control of actin waves and growth cone navigation in developing neurons37
Metabolomic profiling and biomarker identification for early detection and therapeutic targeting of doxorubicin-induced cardiotoxicity37
The ambivalent nature of the relationship between lymphatics and cancer37
Cyclins and CDKs in the regulation of meiosis-specific events37
Circular RNA-regulated autophagy is involved in cancer progression37
Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade37
Characterization of disease-specific alterations in metabolites and effects of mesenchymal stromal cells on dystrophic muscles37
Flow-cytometry reveals mitochondrial DNA accumulation in Saccharomyces cerevisiae cells during cell cycle arrest37
Chloroquine mitigates long-term effects of in vitro culture in mouse embryos37
Ferroptosis Associates With Diagnosis and Prognosis by Promoting Antitumor Immune Response in Melanoma37
Correction: Lmx1a is essential for marginal cell differentiation and stria vascularis formation37
Editorial: Editors’ showcase 2021: Insights in cell growth and division37
Extremely low-frequency electromagnetic fields facilitate both osteoblast and osteoclast activity through Wnt/β-catenin signaling in the zebrafish scale37
Editorial: Reviews in induced pluripotent stem cells37
Combined 3D bioprinting and tissue-specific ECM system reveals the influence of brain matrix on stem cell differentiation37
Stem cell activation in organ culture reveals novel transcriptional programs underlying metabolic, fibrotic, vascular, and immune dysregulation in uterine leiomyomas37
GCN5L: a critical target in energy metabolism pathways37
Editorial: Microtubule-associated molecular motors: Transport mechanisms and role in disease37
Editorial: Cell-to-cell communications in tissue homeostasis and repair36
Editorial: The fertilization success from the Oocyte’s perspective, volume II36
Comprehensive analysis of prognostic value, immune implication and biological function of CPNE1 in clear cell renal cell carcinoma36
A new type of simulated partial gravity apparatus for rats based on a pully-spring system36
Lysophosphatidylethanolamine (LysoPE) in health and disease: a narrative review of its pathophysiological mechanisms and translational potential as a biomarker36
Transcriptomic insights into developmental arrest in fluorescent labeling transgenic Asian elephant (Elephas maximus) embryos via inter-order cloning36
Editorial: Stem cell therapy for hereditary neuromuscular diseases36
Corrigendum: miR-766-3p targeting BCL9L suppressed tumorigenesis, epithelial-mesenchymal transition, and metastasis through the β-catenin signaling pathway in osteosarcoma cells36
Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application36
Transposable element and host silencing activity in gigantic genomes36
Comparison of modulation efficiency between normal and degenerated primate retina36
The polar code for patterning: how polarity and the cytoskeleton orchestrate asymmetric cell division during plant development36
Metabolic control of induced pluripotency36
Sodium pyruvate ameliorates cognitive dysfunction by expanding hippocampal endogenous neural stem cells in tBCCAO mice35
Comprehensive analysis of the prognosis and immune infiltrates for the BET protein family reveals the significance of BRD4 in glioblastoma multiforme35
Imaging and detecting intercellular tensile forces in spheroids and embryoid bodies using lipid-modified DNA probes35
Sox, Fox, and Lmx1b binding sites differentially regulate a Gdf5-Associated regulatory region during elbow development35
The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes35
The emerging role of m6A modification of non-coding RNA in gastrointestinal cancers: a comprehensive review35
Albumin-Based Nanocarriers for the Simultaneous Delivery of Antioxidant Gene and Phytochemical to Combat Oxidative Stress35
In the pursuit of new social neurons. Neurogenesis and social behavior in mice: A systematic review35
From arthritis to erectile dysfunction: potential pathophysiological mechanisms and multidisciplinary integrated management35
Regulating glial morphogenesis: insights from Drosophila34
Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury34
Exploring the diversity of cancer-associated fibroblasts: insights into mechanisms of drug resistance34
Development of a transformer-based deep learning algorithm for diabetic peripheral neuropathy classification using corneal confocal microscopy images34
Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy34
Cell death induction and protection by activation of ubiquitously expressed anion/cation channels. Part 3: the roles and properties of TRPM2 and TRPM734
Editorial: Mechanisms of microenvironment governed plasticity and progression in solid tumors34
Restoring Ag1, an ancient regeneration gene lost in amniotes, accelerates skin healing in mice34
Epigenetic reprogramming in cancer: From diagnosis to treatment34
Unveiling the complexity: assessing models describing the structure and function of the nuclear pore complex34
Small molecules targeting endocytic uptake and recycling pathways34
Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development34
The simultaneous administration of microplastics and cadmium alters rat testicular activity and changes the expression of PTMA, DAAM1 and PREP34
Extracellular vesicles from medicated plasma of Buyang Huanwu decoction-preconditioned neural stem cells accelerate neurological recovery following ischemic stroke34
Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma34
Neuronal cilia in energy homeostasis34
Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate34
CD44s-activated tPA/LRP1-NFκB pathway drives lamellipodia outgrowth in luminal-type breast cancer cells33
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