Frontiers in Cell and Developmental Biology

Papers
(The TQCC of Frontiers in Cell and Developmental Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Methods for automating the analysis of live-cell single-molecule FRET data392
The orobasal organ (of Ackerknecht) is present in prenatal mice194
General Commentary: Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods165
Overexpression of long noncoding RNA 4933425B07Rik leads to renal hypoplasia by inactivating Wnt/β-catenin signaling pathway162
Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos128
Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology121
Editorial: Immunological imbalance: What is its role in intervertebral disc degeneration?115
Editorial: Development, metabolism, senescence and mechanotransduction of bone114
Chronic electrical stimulation with a peripheral suprachoroidal retinal implant: a preclinical safety study of neuroprotective stimulation113
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome111
Editorial: DNA damage response in the context of chromatin107
A novel GCaMP6f-RCS rat model for studying electrical stimulation in the degenerated retina104
Editorial: Post-transcriptional regulation of embryonic and adult myogenesis104
Editorial: The contribution of autophagy to neuronal metabolism103
Targeting N-type calcium channels in young-onset of some neurological diseases102
Regulation of the microprocessor by post-translational modifications98
Real-world database evaluation of drug-associated vitreous opacities and machine learning for clinical interpretability97
Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway95
Integrative analysis of EMT-driving genes identifies a prognostic signature and GJB2 as a potential biomarker in glioblastoma93
Fertility preservation in male cancer patients. Counseling and reproductive outcomes92
CausalFormer-HMC: a hybrid memory-driven transformer with causal reasoning and counterfactual explainability for leukemia diagnosis92
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue90
Effectiveness comparison of pembrolizumab versus other immune checkpoint inhibitors in neoadjuvant chemoimmunotherapy for esophageal squamous cell carcinoma88
PARP9 drives the malignant progression of pancreatic cancer cells by regulating apoptosis, DNA damage, and multidrug efflux systems88
Decoding RNF20: an epigenetic modifier and beyond86
Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification85
Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia85
Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration84
The diverse roles of macrophages in metabolic inflammation and its resolution83
Retraction: MiR-221/222 ameliorates deoxynivalenol-induced apoptosis and proliferation inhibition in intestinal epithelial cells by targeting PTEN83
Mitoregulin, a tiny protein at the crossroads of mitochondrial functioning, stress, and disease82
The regulation of transcription elongation in embryonic stem cells80
Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes79
The role of ANLN in malignant tumors: pathogenesis, treatment resistance and targeted strategies79
Editorial: Ethological dynamics in diorama environments79
Correction: ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer78
Corrigendum: Single-cell RNA sequencing reveals the role of phosphorylation-related genes in hepatocellular carcinoma stem cells78
Krill oil treatment ameliorates lipid metabolism imbalance in chronic unpredicted mild stress-induced depression-like behavior in mice77
Corrigendum: Global research trends of ferroptosis: a rapidly evolving field with enormous potential77
Ferroptosis and Alzheimer’s disease: unraveling the molecular mechanisms and therapeutic opportunities77
Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos76
New strategies for neuro protection in glaucoma75
Editorial: Biophysical target engagement assays in chemical biology and pharmacological research74
Role of UDP-glucose ceramide glucosyltransferase in venous malformation73
Integrated genomic analysis identifies novel low-frequency cis-regulatory variant rs2279658 associated with VSD risk in Chinese children73
Treatment of patients with metastatic epidural spinal cord compression using an enhanced recovery after surgery program72
Coupling of stemness maintenance with cell cycle control in stem cells71
Morinda officinalis oligosaccharides attenuate mitochondria-associated ferroptosis via the NOX4/mitoGPX4 pathway in myocardial ischemia‒reperfusion injury69
Single-cell RNA sequencing reveals cell subpopulations in the tumor microenvironment contributing to hepatocellular carcinoma68
Modeling the spatiotemporal properties of crosstalk between RyR-mediated and IP3R-mediated local Ca2+ release67
The tendon interfascicular basement membrane provides a vascular niche for CD146+ cell subpopulations67
Quantitative analysis of Robertsonian chromosomes inherited by descendants from multiple Rb heterozygotes of Mus m. Domesticus67
The Mkx- TGF-β pathway induced the development of the myodural bridge complex in SD rats66
From organelles to therapy: rethinking combined hepatocellular-cholangiocarcinoma65
Prolactin drives cortical neuron maturation and dendritic development during murine embryonic stem cell differentiation65
Editorial: Personalized medicine for neuromuscular disorders65
Mitochondrial epigenetic mechanisms in cancer: an updated overview65
BDNF-loaded chitosan-based mimetic mussel polymer conduits for repair of peripheral nerve injury64
Enhancement of chemotherapeutic efficacy via non-canonical autophagy induced by Olea europaea in human model of lung adenocarcinoma cells (A549)63
The crosstalk between MYC and mTORC1 during osteoclastogenesis63
Roles of RNA-binding proteins in macrophage function regulation and immunotherapy63
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations62
Crossover interference mechanism: New lessons from plants61
Impact of WTAP in small HCC and paired adjacent non-neoplastic liver tissue on recurrence: A cohort study with external extension analysis61
Regeneration of the dermal skeleton and wound epidermis formation depend on BMP signaling in the caudal fin of platyfish61
A review of cell death pathways in hemorrhagic stroke60
Ultra-short laser processing of 3D bioceramic, porous scaffolds designed by freeze foaming method for orthopedic applications60
Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling59
Synergy between a cytoplasmic vWFA/VIT protein and a WD40-repeat F-box protein controls development in Dictyostelium59
Epigenetic and transcriptomic alterations in the ClC-3-deficient mice consuming a normal diet59
Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway58
Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis57
Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy57
Perspectives on the α5 nicotinic acetylcholine receptor in lung cancer progression57
Disruption of fos causes craniofacial anomalies in developing zebrafish57
JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex56
N6-methyladenosine RNA methylation: From regulatory mechanisms to potential clinical applications55
Palmitoyltransferase DHHC7 mediates protein palmitoylation and is essential for sperm function through the modulation of [Ca2+]i and ROS signaling55
In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers55
GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway53
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems53
Stage- and compartment-specific remodeling of autophagy and selective mitophagy in glaucoma: from aqueous outflow dysfunction to retinal ganglion cell neurodegeneration53
PLANAtools—An interactive gene expression repository for the planarian Schmidtea mediterranea53
B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions53
A FOS/NFKB1-associated Hofbauer cell subset mediates placental niche dysregulation in early-onset fetal growth restriction52
From a stem-cell–centered to a niche-centered view: the core role of collagen networks in hair loss and hair follicle miniaturization52
Mitochondrial DNA abnormalities and metabolic syndrome52
Tumor resident microbiota and response to therapies: An insight on tissue bacterial microbiota52
Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles51
Metabolic biomarkers of neonatal sepsis: identification using metabolomics combined with machine learning51
Control of mitochondrial dynamics and apoptotic pathways by peroxisomes50
From iPSC to manufactured iNK cells using CombiCult® screening platform50
The gut–brain axis: mechanisms linking intestinal dysbiosis with stroke50
Liver X Receptors (LXRs) in cancer-an Eagle’s view on molecular insights and therapeutic opportunities50
Evaluation of the effect of GSK-3β on liver cancer based on the PI3K/AKT pathway49
Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons49
Construction of a prognostic assessment model for colon cancer patients based on immune-related genes and exploration of related immune characteristics49
Quercetin protects porcine oocytes from in vitro aging by reducing oxidative stress and maintaining the mitochondrial functions48
Research progress in deep learning-based fundus image analysis for the diagnosis and prediction of hypertension-related diseases48
Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma48
Regulation of insulin secretion by the post-translational modifications48
Structural regulation and dynamic behaviour of organelles during plant meiosis47
TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure47
Obesity and sudden cardiac death: Prevalence, pathogenesis, prevention and intervention47
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility47
MicroRNA-mediated regulation of hair follicle regeneration: mechanisms, delivery strategies, and translational perspectives47
Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus47
Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke47
EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation47
Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging47
The roles of lncRNA functions and regulatory mechanisms in the diagnosis and treatment of hepatocellular carcinoma47
Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids47
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids47
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation46
MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis46
Mechano-biochemical marine stimulation of inversion, gastrulation, and endomesoderm specification in multicellular Eukaryota46
Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis46
Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma46
Engineered exosomes: a promising design platform for overcoming cancer therapy resistance46
Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental insufficiency during pregnancy46
Paternal impact on the developmental programming of sexual dimorphism46
DNA repair genes play a variety of roles in the development of fish embryos45
Interferon-primed immune landscapes predict immune-related adverse events during immune checkpoint inhibitor therapy45
Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation45
Kinase PLK1 regulates the disassembly of the lateral elements and the assembly of the inner centromere during the diakinesis/metaphase I transition in male mouse meiosis45
Resolution of inflammation during rheumatoid arthritis45
Advances in Traditional Chinese Medicine for chronic obstructive pulmonary disease through multi-omics approaches45
Development, regeneration, and physiological expansion of functional β-cells: Cellular sources and regulators44
Getting cells into shape by calcium-dependent actin cross-linking proteins44
Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins44
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis44
The long-term neurodevelopmental outcomes of febrile seizures and underlying mechanisms44
Mechanisms of CAR T cell exhaustion and current counteraction strategies44
H19 and IGF2 imprinting from embryogenesis to oncogenesis44
Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling44
Cyclodextrin nanoparticles for diagnosis and potential cancer therapy: A systematic review44
Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro43
MEOX2: a homeobox transcription factor with multifaceted biological functions and broad disease associations43
Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss43
Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease43
Involvement of role of HMGB1-NLRP3 pathway in systemic disorders42
Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods42
Comparison of plasma- and saliva-derived exosomal miRNA profiles reveals diagnostic potential in head and neck cancer42
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles42
Interactions between glioblastoma and myeloid cells42
Deciphering the triad of endothelial glycocalyx, von Willebrand Factor, and P-selectin in inflammation-induced coagulation42
Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells42
Weibel-Palade bodies – secretory organelles at the interface of inflammation and hemostasis41
Role of microglia in diabetic neuropathic pain41
Editorial: The self-renewal and reprogramming of cancer stem cells and their crosstalk with the immune microenvironment41
Of mice and men: Pinpointing species differences in adipose tissue biology41
The molecular mechanisms of gas signaling molecules in bronchopulmonary dysplasia related lung injury41
Iron-mediated oxidative stress induces PD-L1 expression via activation of c-Myc in lung adenocarcinoma41
G-patch proteins: important regulators of pre-mRNA splicing and ribosome biogenesis41
GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria41
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery41
Caloric restriction induced epigenetic effects on aging41
The role of retinal Müller cells in diabetic retinopathy and related therapeutic advances41
Autophagy, innate immunity, and cardiac disease41
Systemic inflammatory regulators and risk of acute-on-chronic liver failure: A bidirectional mendelian-randomization study41
Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells40
Quercetin improves and protects Calu-3 airway epithelial barrier function40
Mathematical modeling and application of IL-1β/TNF signaling pathway in regulating chondrocyte apoptosis40
Role of exosomes and exosomal microRNA in muscle–Kidney crosstalk in chronic kidney disease39
Taste receptors affect male reproduction by influencing steroid synthesis39
SIRT3/6/7: promising therapeutic targets for pulmonary fibrosis39
Drosophila: a Tale of regeneration with MYC39
Correction: Polychlorinated biphenyls and breast cancer evidence, mechanisms, and risk management39
NOC1 is a direct MYC target, and its protein interactome dissects its activity in controlling nucleolar function39
Two distinct forms of human BLT2: long-form and short-form BLT239
LncRNA model predicts liver cancer drug resistance and validate in vitro experiments39
Different seminal ejaculated fractions in artificial insemination condition the protein cargo of oviductal and uterine extracellular vesicles in pig39
Exploring the protective mechanisms of the yunpi jiedu tongluo qushi decoction on methotrexate-induced reproductive damage in male rats based on Nrf2/HO-1 signaling pathway39
Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics39
Integrative single-cell and bulk RNA sequencing unravels the role of ACTN1 in promoting lung cancer with brain metastasis and epidermal growth factor receptor-tyrosine kinase inhibitor resistance39
Long-term efficacy and safety of sirolimus for retinal astrocytic hamartoma associated with tuberous sclerosis complex39
MicroRNA target homeobox messenger RNA in HIV induced hematopoietic inhibition38
Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium38
Extremely low-frequency electromagnetic fields facilitate both osteoblast and osteoclast activity through Wnt/β-catenin signaling in the zebrafish scale38
Combined 3D bioprinting and tissue-specific ECM system reveals the influence of brain matrix on stem cell differentiation38
Circular RNA-regulated autophagy is involved in cancer progression38
Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade38
Metabolomic profiling and biomarker identification for early detection and therapeutic targeting of doxorubicin-induced cardiotoxicity38
A novel chemical genetic approach reveals paralog-specific role of ERK1/2 in mouse embryonic stem cell fate control38
MicroRNA: role in macrophage polarisation and colorectal cancer pathogenesis38
Flow-cytometry reveals mitochondrial DNA accumulation in Saccharomyces cerevisiae cells during cell cycle arrest38
Nanotopographic control of actin waves and growth cone navigation in developing neurons38
Correction: Lmx1a is essential for marginal cell differentiation and stria vascularis formation38
Editorial: Editors’ showcase 2021: Insights in cell growth and division38
Editorial: Current methods for detecting and diagnosing stem cell pathogenesis: a focus on translational interventions in the contemporary disease and technology landscape38
Editorial: Mechanisms of hox-driven patterning and morphogenesis38
Characterization of disease-specific alterations in metabolites and effects of mesenchymal stromal cells on dystrophic muscles38
Stem cell activation in organ culture reveals novel transcriptional programs underlying metabolic, fibrotic, vascular, and immune dysregulation in uterine leiomyomas38
Editorial: Microtubule-associated molecular motors: Transport mechanisms and role in disease38
GCN5L: a critical target in energy metabolism pathways38
Editorial: Reviews in induced pluripotent stem cells38
A new type of simulated partial gravity apparatus for rats based on a pully-spring system37
Comparison of modulation efficiency between normal and degenerated primate retina37
Lysophosphatidylethanolamine (LysoPE) in health and disease: a narrative review of its pathophysiological mechanisms and translational potential as a biomarker37
Multi-omics analysis reveals a protective role of endogenous proline in sheep oocyte vitrification and its therapeutic application37
Editorial: Stem cell therapy for hereditary neuromuscular diseases37
Editorial: The fertilization success from the Oocyte’s perspective, volume II37
Editorial: Cell-to-cell communications in tissue homeostasis and repair37
Transcriptomic insights into developmental arrest in fluorescent labeling transgenic Asian elephant (Elephas maximus) embryos via inter-order cloning37
Corrigendum: miR-766-3p targeting BCL9L suppressed tumorigenesis, epithelial-mesenchymal transition, and metastasis through the β-catenin signaling pathway in osteosarcoma cells37
Transposable element and host silencing activity in gigantic genomes37
Sodium pyruvate ameliorates cognitive dysfunction by expanding hippocampal endogenous neural stem cells in tBCCAO mice36
Albumin-Based Nanocarriers for the Simultaneous Delivery of Antioxidant Gene and Phytochemical to Combat Oxidative Stress36
Cell death induction and protection by activation of ubiquitously expressed anion/cation channels. Part 3: the roles and properties of TRPM2 and TRPM736
The simultaneous administration of microplastics and cadmium alters rat testicular activity and changes the expression of PTMA, DAAM1 and PREP36
The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes36
Regulating glial morphogenesis: insights from Drosophila36
Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development36
Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate36
From arthritis to erectile dysfunction: potential pathophysiological mechanisms and multidisciplinary integrated management36
Comprehensive analysis of the prognosis and immune infiltrates for the BET protein family reveals the significance of BRD4 in glioblastoma multiforme36
The emerging role of m6A modification of non-coding RNA in gastrointestinal cancers: a comprehensive review36
Editorial: Mechanisms of microenvironment governed plasticity and progression in solid tumors36
Small molecules targeting endocytic uptake and recycling pathways35
Neuronal cilia in energy homeostasis35
Prognosis and therapeutic significance of IGF-1R-related signaling pathway gene signature in glioma35
PtosisDiffusion: a training-free workflow for precisely predicting post-operative appearance in blepharoptosis patients based on diffusion models35
Restoring Ag1, an ancient regeneration gene lost in amniotes, accelerates skin healing in mice35
Extracellular vesicles from medicated plasma of Buyang Huanwu decoction-preconditioned neural stem cells accelerate neurological recovery following ischemic stroke35
ZebraReg—a novel platform for discovering regulators of cardiac regeneration using zebrafish35
Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway35
Unveiling the complexity: assessing models describing the structure and function of the nuclear pore complex35
Development of a transformer-based deep learning algorithm for diabetic peripheral neuropathy classification using corneal confocal microscopy images35
Carcinogenesis trajectories35
In vivo PSC differentiation as a platform to identify factors for improving the engraftability of cultured muscle stem cells34
Tumor-derived sphingosine-1-phosphate shapes angiogenesis in the acidic microenvironment of osteosarcoma via paracrine and autocrine signaling34
Age-related lncRNA alterations of SDHAP2_miR-17-5p/miR-20b-5p_RAB11FIP1 ceRNA network in donor-derived human limbal epithelial cells34
Unraveling the path to osteoarthritis management: targeting chondrocyte apoptosis for therapeutic intervention34
Porcn is essential for growth and invagination of the mammalian optic cup34
Integrins in cancer stem cells34
Corrigendum: Characterizing the neutrophilic inflammation in chronic rhinosinusitis with nasal polyps34
Transcriptome analysis identifies EDA1 variants disrupt FOSB-mediated regulation of odontogenic epithelial cell behaviors during dental germ development34
Analysis of factors influencing the efficacy of NAC and prognosis between HER2-zero and HER2-low HR negative breast cancer34
Regulation of p53 by the mitotic surveillance/stopwatch pathway: implications in neurodevelopment and cancer34
Metabolic reprogramming and plasticity of cancer stem cells34
Muscle fibro-adipogenic progenitors from a single-cell perspective: Focus on their “virtual” secretome34
Development and Validation of a Novel Mitochondrion and Ferroptosis-Related Long Non-Coding RNA Prognostic Signature in Hepatocellular Carcinoma34
Retraction: NR2F1-AS1/miR-190a/PHLDB2 induces the epithelial–mesenchymal transformation process in gastric cancer by promoting phosphorylation of AKT334
Salivary miRNAs and cytokines associated with diagnosis and prognosis of oral squamous cell carcinoma34
Stress-response exhaustion in intervertebral disc degeneration34
Emerging cellular themes in leukodystrophies33
EV products obtained from iPSC-derived MSCs show batch-to-batch variations in their ability to modulate allogeneic immune responses in vitro33
Metabolic control of induced pluripotency33
Insulin secretion hot spots in pancreatic β cells as secreting adhesions33
Cyclins and CDKs in the regulation of meiosis-specific events33
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