Frontiers in Cell and Developmental Biology

Papers
(The median citation count of Frontiers in Cell and Developmental Biology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Methods for automating the analysis of live-cell single-molecule FRET data349
Construction of a prognostic assessment model for colon cancer patients based on immune-related genes and exploration of related immune characteristics153
General Commentary: Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods148
The orobasal organ (of Ackerknecht) is present in prenatal mice148
Overexpression of long noncoding RNA 4933425B07Rik leads to renal hypoplasia by inactivating Wnt/β-catenin signaling pathway138
Editorial: The self-renewal and reprogramming of cancer stem cells and their crosstalk with the immune microenvironment136
Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos127
Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology122
CausalFormer-HMC: a hybrid memory-driven transformer with causal reasoning and counterfactual explainability for leukemia diagnosis117
Emerging Roles of Long Noncoding RNAs in Breast Cancer Epigenetics and Epitranscriptomics110
TRPV1 channel in spermatozoa is a molecular target for ROS-mediated sperm dysfunction and differentially expressed in both natural and ART pregnancy failure104
GNA13 promotes brain metastasis of non-small cell lung cancer and EMT through the WNT/β catenin signaling pathway101
Fertility preservation in male cancer patients. Counseling and reproductive outcomes97
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue94
Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma93
BDNF-loaded chitosan-based mimetic mussel polymer conduits for repair of peripheral nerve injury92
Mitochondrial epigenetic mechanisms in cancer: an updated overview92
Editorial: Personalized medicine for neuromuscular disorders92
Getting cells into shape by calcium-dependent actin cross-linking proteins90
Kinase PLK1 regulates the disassembly of the lateral elements and the assembly of the inner centromere during the diakinesis/metaphase I transition in male mouse meiosis88
Emerin interacts with histone methyltransferases to regulate repressive chromatin at the nuclear periphery88
JAZF1: A metabolic actor subunit of the NuA4/TIP60 chromatin modifying complex88
Resolution of inflammation during rheumatoid arthritis87
Research progress in deep learning-based fundus image analysis for the diagnosis and prediction of hypertension-related diseases86
G-patch proteins: important regulators of pre-mRNA splicing and ribosome biogenesis85
From organelles to therapy: rethinking combined hepatocellular-cholangiocarcinoma83
Role of microglia in diabetic neuropathic pain82
Iron-mediated oxidative stress induces PD-L1 expression via activation of c-Myc in lung adenocarcinoma82
Evaluation of the effect of GSK-3β on liver cancer based on the PI3K/AKT pathway82
Genome-Wide DNA Methylation Profiling in CD8 T-Cells and Gamma Delta T-Cells of Asian Indian Patients With Takayasu Arteritis82
Characterization of mesenchymal stem cells in pre-B acute lymphoblastic leukemia81
Multimodal reasoning agent for enhanced ophthalmic decision-making: a preliminary real-world clinical validation80
Effectiveness comparison of pembrolizumab versus other immune checkpoint inhibitors in neoadjuvant chemoimmunotherapy for esophageal squamous cell carcinoma79
Metabolic biomarkers of neonatal sepsis: identification using metabolomics combined with machine learning78
N6-methyladenosine RNA methylation: From regulatory mechanisms to potential clinical applications78
Decoding RNF20: an epigenetic modifier and beyond77
The roles of lncRNA functions and regulatory mechanisms in the diagnosis and treatment of hepatocellular carcinoma76
ERK5 Signalling and Resistance to ERK1/2 Pathway Therapeutics: The Path Less Travelled?76
Editorial: Development, metabolism, senescence and mechanotransduction of bone73
Editorial: Immunological imbalance: What is its role in intervertebral disc degeneration?73
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome71
Chronic electrical stimulation with a peripheral suprachoroidal retinal implant: a preclinical safety study of neuroprotective stimulation71
Editorial: DNA damage response in the context of chromatin70
Editorial: WT1 in Development and Disease69
Maternal Factor Dppa3 Activates 2C-Like Genes and Depresses DNA Methylation in Mouse Embryonic Stem Cells69
Editorial: Post-transcriptional regulation of embryonic and adult myogenesis68
Targeting N-type calcium channels in young-onset of some neurological diseases68
EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation68
Editorial: The contribution of autophagy to neuronal metabolism68
Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling68
A novel GCaMP6f-RCS rat model for studying electrical stimulation in the degenerated retina68
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles68
Regulation of the microprocessor by post-translational modifications68
Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes67
Correction: ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer67
Corrigendum: Global research trends of ferroptosis: a rapidly evolving field with enormous potential66
Corrigendum: Single-cell RNA sequencing reveals the role of phosphorylation-related genes in hepatocellular carcinoma stem cells66
Integrative analysis of EMT-driving genes identifies a prognostic signature and GJB2 as a potential biomarker in glioblastoma66
Amniotic mesenchymal stem cells attenuate diabetic cardiomyopathy by inhibiting pyroptosis via modulation of the TLR4/NF-κb/NLRP3 pathway65
Real-world database evaluation of drug-associated vitreous opacities and machine learning for clinical interpretability65
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems65
Control of mitochondrial dynamics and apoptotic pathways by peroxisomes64
Granulosa Cells Improved Mare Oocyte Cytoplasmic Maturation by Providing Collagens63
Editorial: Ethological dynamics in diorama environments63
The role of ANLN in malignant tumors: pathogenesis, treatment resistance and targeted strategies62
Obesity and sudden cardiac death: Prevalence, pathogenesis, prevention and intervention62
MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis61
Regulation of insulin secretion by the post-translational modifications61
The tendon interfascicular basement membrane provides a vascular niche for CD146+ cell subpopulations60
Liver X Receptors (LXRs) in cancer-an Eagle’s view on molecular insights and therapeutic opportunities60
Involvement of role of HMGB1-NLRP3 pathway in systemic disorders60
Caloric restriction induced epigenetic effects on aging59
Enhancement of chemotherapeutic efficacy via non-canonical autophagy induced by Olea europaea in human model of lung adenocarcinoma cells (A549)59
Limb Mesoderm and Head Ectomesenchyme Both Express a Core Transcriptional Program During Chondrocyte Differentiation58
Widespread distribution of lymphatic vessels in human dura mater remote from sinus veins57
Quantitative analysis of Robertsonian chromosomes inherited by descendants from multiple Rb heterozygotes of Mus m. Domesticus57
Interactions between glioblastoma and myeloid cells57
The long-term neurodevelopmental outcomes of febrile seizures and underlying mechanisms57
Engineered exosomes: a promising design platform for overcoming cancer therapy resistance56
Of mice and men: Pinpointing species differences in adipose tissue biology56
Mechanisms of CAR T cell exhaustion and current counteraction strategies56
The Mkx- TGF-β pathway induced the development of the myodural bridge complex in SD rats56
mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila55
B cell-T cell interplay in immune regulation: A focus on follicular regulatory T and regulatory B cell functions55
Targeted Plasmalogen Supplementation: Effects on Blood Plasmalogens, Oxidative Stress Biomarkers, Cognition, and Mobility in Cognitively Impaired Persons55
Systemic inflammatory regulators and risk of acute-on-chronic liver failure: A bidirectional mendelian-randomization study55
Modeling the spatiotemporal properties of crosstalk between RyR-mediated and IP3R-mediated local Ca2+ release55
Differential regulation of MYC expression by PKHD1/Pkhd1 in human and mouse kidneys: phenotypic implications for recessive polycystic kidney disease55
Prolactin drives cortical neuron maturation and dendritic development during murine embryonic stem cell differentiation55
Paternal impact on the developmental programming of sexual dimorphism54
Single-cell RNA sequencing reveals cell subpopulations in the tumor microenvironment contributing to hepatocellular carcinoma54
The role of retinal Müller cells in diabetic retinopathy and related therapeutic advances54
Cell-free regenerative medicine: identifying the best source of mesenchymal stem cells for skin therapy in Systemic Sclerosis54
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation54
Vimentin Tail Segments Are Differentially Exposed at Distinct Cellular Locations and in Response to Stress54
Deciphering the triad of endothelial glycocalyx, von Willebrand Factor, and P-selectin in inflammation-induced coagulation53
Morinda officinalis oligosaccharides attenuate mitochondria-associated ferroptosis via the NOX4/mitoGPX4 pathway in myocardial ischemia‒reperfusion injury53
Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro53
Structural regulation and dynamic behaviour of organelles during plant meiosis52
Advances in understanding the regulation of pluripotency fate transition in embryonic stem cells52
Crossover interference mechanism: New lessons from plants52
A review of cell death pathways in hemorrhagic stroke52
Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value51
Ultra-short laser processing of 3D bioceramic, porous scaffolds designed by freeze foaming method for orthopedic applications50
Targeting microglia polarization with Chinese herb-derived natural compounds for neuroprotection in ischemic stroke50
OAS3 is a Co-Immune Biomarker Associated With Tumour Microenvironment, Disease Staging, Prognosis, and Treatment Response in Multiple Cancer Types50
Regeneration of the dermal skeleton and wound epidermis formation depend on BMP signaling in the caudal fin of platyfish50
The regulation of transcription elongation in embryonic stem cells49
Advances in Traditional Chinese Medicine for chronic obstructive pulmonary disease through multi-omics approaches49
Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental insufficiency during pregnancy49
Roles of RNA-binding proteins in macrophage function regulation and immunotherapy49
Tumor resident microbiota and response to therapies: An insight on tissue bacterial microbiota48
Disruption of fos causes craniofacial anomalies in developing zebrafish48
Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis48
In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers48
Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway48
PARP9 drives the malignant progression of pancreatic cancer cells by regulating apoptosis, DNA damage, and multidrug efflux systems48
New strategies for neuro protection in glaucoma47
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility47
Impact of WTAP in small HCC and paired adjacent non-neoplastic liver tissue on recurrence: A cohort study with external extension analysis47
Perspectives on the α5 nicotinic acetylcholine receptor in lung cancer progression47
GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria46
Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration46
Mitoregulin, a tiny protein at the crossroads of mitochondrial functioning, stress, and disease46
Development, regeneration, and physiological expansion of functional β-cells: Cellular sources and regulators46
The diverse roles of macrophages in metabolic inflammation and its resolution46
Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids45
Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging45
Retraction: MiR-221/222 ameliorates deoxynivalenol-induced apoptosis and proliferation inhibition in intestinal epithelial cells by targeting PTEN45
Comparison of plasma- and saliva-derived exosomal miRNA profiles reveals diagnostic potential in head and neck cancer45
Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos44
Ferroptosis and Alzheimer’s disease: unraveling the molecular mechanisms and therapeutic opportunities44
DNA repair genes play a variety of roles in the development of fish embryos44
Editorial: Biophysical target engagement assays in chemical biology and pharmacological research44
Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification44
Krill oil treatment ameliorates lipid metabolism imbalance in chronic unpredicted mild stress-induced depression-like behavior in mice44
Weibel-Palade bodies – secretory organelles at the interface of inflammation and hemostasis43
Mechano-biochemical marine stimulation of inversion, gastrulation, and endomesoderm specification in multicellular Eukaryota43
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations43
Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons43
Synovial sarcoma of the head and neck: A review of reported cases on the clinical characteristics and treatment methods43
Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus43
The crosstalk between MYC and mTORC1 during osteoclastogenesis43
Single-Cell RNA Sequencing Profiles Identify Important Pathophysiologic Factors in the Progression of Diabetic Nephropathy42
Quercetin protects porcine oocytes from in vitro aging by reducing oxidative stress and maintaining the mitochondrial functions42
Synergy between a cytoplasmic vWFA/VIT protein and a WD40-repeat F-box protein controls development in Dictyostelium42
Effects of Transcription-Dependent Physical Perturbations on the Chromosome Dynamics in Living Cells42
Tumor suppressor function of formyl peptide receptor 1 in gastrointestinal cancers: a focus on the underlying signaling42
Epigenetic and transcriptomic alterations in the ClC-3-deficient mice consuming a normal diet42
Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy42
Coupling of stemness maintenance with cell cycle control in stem cells41
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids41
Treatment of patients with metastatic epidural spinal cord compression using an enhanced recovery after surgery program41
Mitochondrial DNA abnormalities and metabolic syndrome41
Cyclodextrin nanoparticles for diagnosis and potential cancer therapy: A systematic review41
Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss41
H19 and IGF2 imprinting from embryogenesis to oncogenesis41
In the pursuit of new social neurons. Neurogenesis and social behavior in mice: A systematic review40
Amelioration of pregnancy outcomes in a pregnant rat model with deep venous thrombosis following the transplantation of bone marrow mesenchymal stem cells40
Integrated genomic analysis identifies novel low-frequency cis-regulatory variant rs2279658 associated with VSD risk in Chinese children40
Modulation of the pre-metastatic bone niche: molecular changes mediated by bone-homing prostate cancer extracellular vesicles40
Role of UDP-glucose ceramide glucosyltransferase in venous malformation40
Seminal cadmium affects human sperm motility through stable binding to the cell membrane40
PLANAtools—An interactive gene expression repository for the planarian Schmidtea mediterranea40
Squeezing the eggs to grow: The mechanobiology of mammalian folliculogenesis40
The emerging role of m6A modification of non-coding RNA in gastrointestinal cancers: a comprehensive review40
NOC1 is a direct MYC target, and its protein interactome dissects its activity in controlling nucleolar function40
Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma40
Autophagy, innate immunity, and cardiac disease40
Porcn is essential for growth and invagination of the mammalian optic cup39
Extracellular vesicles from medicated plasma of Buyang Huanwu decoction-preconditioned neural stem cells accelerate neurological recovery following ischemic stroke39
Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway39
Editorial: Functions and regulation of p90RSK and its family: mechanisms, roles in diseases, and implications in therapeutics39
Transposable element and host silencing activity in gigantic genomes39
Two distinct forms of human BLT2: long-form and short-form BLT239
Chloroquine mitigates long-term effects of in vitro culture in mouse embryos39
Transcriptional regulation in the absence of inositol trisphosphate receptor calcium signaling39
Comprehensive analysis of the prognosis and immune infiltrates for the BET protein family reveals the significance of BRD4 in glioblastoma multiforme39
Stem cell therapy offers new hope for the treatment of Alzheimer’s disease39
Exploring the protective mechanisms of the yunpi jiedu tongluo qushi decoction on methotrexate-induced reproductive damage in male rats based on Nrf2/HO-1 signaling pathway39
A new type of simulated partial gravity apparatus for rats based on a pully-spring system38
Repetitive DNA Sequences in the Human Y Chromosome and Male Infertility38
ZebraReg—a novel platform for discovering regulators of cardiac regeneration using zebrafish38
Age-related lncRNA alterations of SDHAP2_miR-17-5p/miR-20b-5p_RAB11FIP1 ceRNA network in donor-derived human limbal epithelial cells38
Combined 3D bioprinting and tissue-specific ECM system reveals the influence of brain matrix on stem cell differentiation38
Protective effects of paederoside in rotenone-induced cellular models of Parkinson’s disease38
Regulating glial morphogenesis: insights from Drosophila38
Editorial: Microtubule-associated molecular motors: Transport mechanisms and role in disease38
Muscle fibro-adipogenic progenitors from a single-cell perspective: Focus on their “virtual” secretome38
Exploring the diversity of cancer-associated fibroblasts: insights into mechanisms of drug resistance38
Integrins in cancer stem cells38
The ambivalent nature of the relationship between lymphatics and cancer38
MicroRNA: role in macrophage polarisation and colorectal cancer pathogenesis37
Editorial: The fertilization success from the Oocyte’s perspective, volume II37
MicroRNA target homeobox messenger RNA in HIV induced hematopoietic inhibition37
Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium37
From arthritis to erectile dysfunction: potential pathophysiological mechanisms and multidisciplinary integrated management37
The fibularis tertius muscle revisited: comparative anatomy, developmental classification, and evolutionary-clinical implications37
A novel chemical genetic approach reveals paralog-specific role of ERK1/2 in mouse embryonic stem cell fate control37
Editorial: Current methods for detecting and diagnosing stem cell pathogenesis: a focus on translational interventions in the contemporary disease and technology landscape37
Long-term efficacy and safety of sirolimus for retinal astrocytic hamartoma associated with tuberous sclerosis complex37
Chromatin remodeling complexes: architects influencing breast cancer progression37
Augmenting mesenchymal stem cell therapy for osteoarthritis via inflammatory priming: a comparative study on mesenchymal stem cells derived from various perinatal tissue sources37
Editorial: Mechanisms of hox-driven patterning and morphogenesis37
Characterization of disease-specific alterations in metabolites and effects of mesenchymal stromal cells on dystrophic muscles36
Comprehensive analysis of prognostic value, immune implication and biological function of CPNE1 in clear cell renal cell carcinoma36
In vivo PSC differentiation as a platform to identify factors for improving the engraftability of cultured muscle stem cells36
Editorial: Editors’ showcase 2021: Insights in cell growth and division36
Interaction between epidermal growth factor receptor and C-C motif chemokine receptor 2 in the ovulatory cascade36
Ferroptosis Associates With Diagnosis and Prognosis by Promoting Antitumor Immune Response in Melanoma36
Transcriptomic insights into developmental arrest in fluorescent labeling transgenic Asian elephant (Elephas maximus) embryos via inter-order cloning36
The Sperm Olfactory Receptor OLFR601 is Dispensable for Mouse Fertilization36
Extremely low-frequency electromagnetic fields facilitate both osteoblast and osteoclast activity through Wnt/β-catenin signaling in the zebrafish scale36
Development and Validation of a Novel Mitochondrion and Ferroptosis-Related Long Non-Coding RNA Prognostic Signature in Hepatocellular Carcinoma36
Comparison of modulation efficiency between normal and degenerated primate retina36
Significance of Liver Zonation in Hepatocellular Carcinoma35
Divergent features of ERβ isoforms in triple negative breast cancer: progress and implications for further research35
A novel diG motif in ORF3a protein of SARS-Cov-2 for intracellular transport35
Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy35
Carcinogenesis trajectories35
The promising roles of macrophages in geriatric hip fracture35
GCN5L: a critical target in energy metabolism pathways35
Editorial: Stem cell therapy for hereditary neuromuscular diseases35
Metabolic patterns predispose human pluripotent stem cells to spatial organization of cell fate35
Restoring Ag1, an ancient regeneration gene lost in amniotes, accelerates skin healing in mice34
Editorial: Mechanisms of microenvironment governed plasticity and progression in solid tumors34
Dyslexia associated gene KIAA0319 regulates cell cycle during human neuroepithelial cell development34
Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation34
Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics34
Stem cell activation in organ culture reveals novel transcriptional programs underlying metabolic, fibrotic, vascular, and immune dysregulation in uterine leiomyomas34
Recent progress of nanomedicine in the treatment of Alzheimer’s disease34
Analysis of factors influencing the efficacy of NAC and prognosis between HER2-zero and HER2-low HR negative breast cancer34
Small molecules targeting endocytic uptake and recycling pathways34
Embryo-derived trypsin-induced calcium entry is inhibited by endometrial infertility factor, LEFTY234
Taste receptors affect male reproduction by influencing steroid synthesis34
Unraveling the path to osteoarthritis management: targeting chondrocyte apoptosis for therapeutic intervention34
Mechanistic insights into adipose-derived stem cells and exosomes in ischemia-reperfusion injury repair: from shared pathways to organ-specific therapeutics34
Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury34
Corrigendum: Characterizing the neutrophilic inflammation in chronic rhinosinusitis with nasal polyps34
Retraction: NR2F1-AS1/miR-190a/PHLDB2 induces the epithelial–mesenchymal transformation process in gastric cancer by promoting phosphorylation of AKT334
Transcriptome analysis identifies EDA1 variants disrupt FOSB-mediated regulation of odontogenic epithelial cell behaviors during dental germ development34
Corrigendum: miR-766-3p targeting BCL9L suppressed tumorigenesis, epithelial-mesenchymal transition, and metastasis through the β-catenin signaling pathway in osteosarcoma cells34
Development of a transformer-based deep learning algorithm for diabetic peripheral neuropathy classification using corneal confocal microscopy images34
Mfsd8 Modulates Growth and the Early Stages of Multicellular Development in Dictyostelium discoideum34
A Single-Cell Characterization of Human Post-implantation Embryos Cultured In Vitro Delineates Morphogenesis in Primary Syncytialization34
MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites33
Role of SNAREs in Unconventional Secretion—Focus on the VAMP7-Dependent Secretion33
Correction: Polychlorinated biphenyls and breast cancer evidence, mechanisms, and risk management33
Update on the pathogenesis and genetics of Paget’s disease of bone33
Cyclins and CDKs in the regulation of meiosis-specific events33
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