OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Cell and Developmental Biology is 65. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Involvement of role of HMGB1-NLRP3 pathway in systemic disorders	221
Activation of telomerase via madecassic acid enhances the developmental competence of the SCNT-derived bovine embryos	213
MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis	195
CCL2 promotes osteogenesis by facilitating macrophage migration during acute inflammation	188
Cancer stem cells are prevalent in the basal-like 2 and mesenchymal triple-negative breast cancer subtypes in vitro	180
Plasmodium Circumsporozoite Protein Enhances the Efficacy of Gefitinib in Lung Adenocarcinoma Cells by Inhibiting Autophagy via Proteasomal Degradation of LC3B	157
Autophagy and Mitochondrial Homeostasis During Infection: A Double-Edged Sword	156
A multi-mineral intervention to counter pro-inflammatory activity and to improve the barrier in human colon organoids	149
Correction: ELOVL2 mediated stabilization of AR contributes to enzalutamide resistance in prostate cancer	138
Promoter Hypomethylation of TGFBR3 as a Risk Factor of Alzheimer’s Disease: An Integrated Epigenomic-Transcriptomic Analysis	138
Amyloid-induced mitochondrial network disruption in neurons monitored by STED super-resolution imaging	136
Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling	133
Corrigendum: Global research trends of ferroptosis: a rapidly evolving field with enormous potential	123
Interactions between glioblastoma and myeloid cells	116
Transcriptional profiling identifies IL-33-expressing intestinal stromal cells as a signaling hub poised to interact with enteric neurons	116
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility	113
Low pH Attenuates Apoptosis by Suppressing the Volume-Sensitive Outwardly Rectifying (VSOR) Chloride Current in Chondrocytes	106
Systemic inflammatory regulators and risk of acute-on-chronic liver failure: A bidirectional mendelian-randomization study	105
A review of cell death pathways in hemorrhagic stroke	101
Quaking but not parkin is the major tumor suppressor in 6q deleted region in glioblastoma	101
Genome-Wide DNA Methylation Profiling in CD8 T-Cells and Gamma Delta T-Cells of Asian Indian Patients With Takayasu Arteritis	94
Large Scale Identification of Osteosarcoma Pathogenic Genes by Multiple Extreme Learning Machine	93
Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss	92
Corrigendum: Postnatal Developmental Expression Profile Classifies the Indusium Griseum as a Distinct Subfield of the Hippocampal Formation	92
Editorial: Development, metabolism, senescence and mechanotransduction of bone	92

Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus	88
Multi-Omics Investigations Revealed Underlying Molecular Mechanisms Associated With Tumor Stiffness and Identified Sunitinib as a Potential Therapy for Reducing Stiffness in Pituitary Adenomas	87
Chronic electrical stimulation with a peripheral suprachoroidal retinal implant: a preclinical safety study of neuroprotective stimulation	86
Characterization of Genomic Alterations in Colorectal Liver Metastasis and Their Prognostic Value	85
SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome	84
Editorial: Personalized medicine for neuromuscular disorders	82
Editorial: DNA damage response in the context of chromatin	82
Maternal Factor Dppa3 Activates 2C-Like Genes and Depresses DNA Methylation in Mouse Embryonic Stem Cells	81
Shank3 related muscular hypotonia is accompanied by increased intracellular calcium concentrations and ion channel dysregulation in striated muscle tissue	80
Caloric restriction induced epigenetic effects on aging	80
Emerging Roles of Long Noncoding RNAs in Breast Cancer Epigenetics and Epitranscriptomics	80
Editorial: WT1 in Development and Disease	79
Exosomal miRNAs and lncRNAs: The Modulator Keys of Cancer-Associated Fibroblasts in the Genesis and Progression of Malignant Neoplasms	77
Integrated genomic analysis identifies novel low-frequency cis-regulatory variant rs2279658 associated with VSD risk in Chinese children	76
The regulation of transcription elongation in embryonic stem cells	76
Control of mitochondrial dynamics and apoptotic pathways by peroxisomes	75
Multi-Level Computational Modeling of Anti-Cancer Dendritic Cell Vaccination Utilized to Select Molecular Targets for Therapy Optimization	74
Impact of WTAP in small HCC and paired adjacent non-neoplastic liver tissue on recurrence: A cohort study with external extension analysis	74
EdeepSADPr: an extensive deep-learning architecture for prediction of the in situ crosstalks of serine phosphorylation and ADP-ribosylation	74
Editorial: Immunological imbalance: What is its role in intervertebral disc degeneration?	73
Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification	73
GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria	72
A Selective Review of the Excitatory-Inhibitory Imbalance in Schizophrenia: Underlying Biology, Genetics, Microcircuits, and Symptoms	72
Editorial: Biophysical target engagement assays in chemical biology and pharmacological research	71
Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes	71
Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations	71
OAS3 is a Co-Immune Biomarker Associated With Tumour Microenvironment, Disease Staging, Prognosis, and Treatment Response in Multiple Cancer Types	70
Editorial: Post-transcriptional regulation of embryonic and adult myogenesis	70
A novel GCaMP6f-RCS rat model for studying electrical stimulation in the degenerated retina	70
Targeting N-type calcium channels in young-onset of some neurological diseases	69
Editorial: The contribution of autophagy to neuronal metabolism	69
Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis	68
The crosstalk between MYC and mTORC1 during osteoclastogenesis	67
Granulosa Cells Improved Mare Oocyte Cytoplasmic Maturation by Providing Collagens	67
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles	66
Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems	66
Weibel-Palade bodies – secretory organelles at the interface of inflammation and hemostasis	66
Ultra-short laser processing of 3D bioceramic, porous scaffolds designed by freeze foaming method for orthopedic applications	65
Negatively Regulated by miR-29c-3p, MTFR1 Promotes the Progression and Glycolysis in Lung Adenocarcinoma via the AMPK/mTOR Signalling Pathway	65
Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis	65