OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Cell and Developmental Biology is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-09-01 to 2023-09-01.)

Article	Citations
Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype	427
Iron Metabolism in Ferroptosis	288
Mitophagy, Mitochondrial Homeostasis, and Cell Fate	243
PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance	243
Oxidative Damage and Antioxidant Defense in Ferroptosis	190
T Cell Dysfunction and Exhaustion in Cancer	173
Mitophagy: An Emerging Role in Aging and Age-Associated Diseases	171
Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications	168
Molecular Mechanisms of Radiation-Induced Cancer Cell Death: A Primer	165
MicroRNAs: From Mechanism to Organism	162
Characteristics and Biomarkers of Ferroptosis	152
Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors	147
Beneficial and Detrimental Effects of Reactive Oxygen Species on Lifespan: A Comprehensive Review of Comparative and Experimental Studies	141
Metabolism of Amino Acids in Cancer	138
FGF Signaling Pathway: A Key Regulator of Stem Cell Pluripotency	128
In vitro Models of Neurodegenerative Diseases	128
Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate	123
Adult Stem Cells for Bone Regeneration and Repair	120
TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering	116
Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies	116
The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models	116
Energy Metabolism Regulates Stem Cell Pluripotency	115
A Brief Review of Current Maturation Methods for Human Induced Pluripotent Stem Cells-Derived Cardiomyocytes	110
On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges?	110
A Revised Perspective of Skeletal Stem Cell Biology	110

Diverse Role of TGF-β in Kidney Disease	108
The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues	108
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach	107
The Emerging Role of the Mammalian Glycocalyx in Functional Membrane Organization and Immune System Regulation	105
The Pyroptosis-Related Signature Predicts Prognosis and Indicates Immune Microenvironment Infiltration in Gastric Cancer	104
N6-Methylandenosine-Related lncRNAs Are Potential Biomarkers for Predicting the Overall Survival of Lower-Grade Glioma Patients	103
The Roles of Histone Deacetylases and Their Inhibitors in Cancer Therapy	101
Laboratory Testing Methods for Novel Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)	93
The Impact of PM2.5 on the Host Defense of Respiratory System	93
Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects	93
Molecular Bases of VEGFR-2-Mediated Physiological Function and Pathological Role	91
Immunomodulatory Effect of Adipose-Derived Stem Cells: The Cutting Edge of Clinical Application	90
Targeting Rho GTPase Signaling Networks in Cancer	90
Endometrial and Menstrual Blood Mesenchymal Stem/Stromal Cells: Biological Properties and Clinical Application	89
Pseudogene-Derived lncRNAs and Their miRNA Sponging Mechanism in Human Cancer	88
Ferroptosis-Related Gene Signature Predicts Glioma Cell Death and Glioma Patient Progression	87
Cathepsin K: The Action in and Beyond Bone	85
Emerging Signal Regulating Potential of Genistein Against Alzheimer’s Disease: A Promising Molecule of Interest	85
The mTOR–Autophagy Axis and the Control of Metabolism	84
Emerging Roles of Lipophagy in Health and Disease	83
Interplay Between Lipid Metabolism and Autophagy	83
CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention	83
New Insights of Emerging SARS-CoV-2: Epidemiology, Etiology, Clinical Features, Clinical Treatment, and Prevention	82
The Inhibitory Effect of Curcumin on Virus-Induced Cytokine Storm and Its Potential Use in the Associated Severe Pneumonia	82
Autophagy and Stem Cells: Self-Eating for Self-Renewal	82
The Function of the HGF/c-Met Axis in Hepatocellular Carcinoma	81
Recent Advances of Osterix Transcription Factor in Osteoblast Differentiation and Bone Formation	81
Tumor Endothelial Cells (TECs) as Potential Immune Directors of the Tumor Microenvironment – New Findings and Future Perspectives	80
Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction	80
Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2	80
Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction	80
Mechanoregulation of YAP and TAZ in Cellular Homeostasis and Disease Progression	79
Molecular Mechanisms of Cardiomyocyte Death in Drug-Induced Cardiotoxicity	79
Neuroinflammation as a Factor of Neurodegenerative Disease: Thalidomide Analogs as Treatments	78
MicroRNA Involvement in Signaling Pathways During Viral Infection	78
Potential Roles of Exosomes in Parkinson’s Disease: From Pathogenesis, Diagnosis, and Treatment to Prognosis	78
Pleiotropic Effects of mTOR and Autophagy During Development and Aging	75
The Mechanics of Mitotic Cell Rounding	75
Contribution of TGF-Beta-Mediated NLRP3-HMGB1 Activation to Tubulointerstitial Fibrosis in Rat With Angiotensin II-Induced Chronic Kidney Disease	74
Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic Information	74
X Inactivation and Escape: Epigenetic and Structural Features	74
BMSC-Derived Exosomal miR-29a Promotes Angiogenesis and Osteogenesis	74
Hepatic Stellate Cells and Hepatocarcinogenesis	73
The Role of Exosomes and Exosomal MicroRNA in Cardiovascular Disease	73
Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Origin, Polarization, Function, and Reprogramming	73
Tumor Microenvironment in Ovarian Cancer: Function and Therapeutic Strategy	73
Bearing My Heart: The Role of Extracellular Matrix on Cardiac Development, Homeostasis, and Injury Response	72
Nicotinamide Mononucleotide: A Promising Molecule for Therapy of Diverse Diseases by Targeting NAD+ Metabolism	72
MitophAging: Mitophagy in Aging and Disease	72