Frontiers in Bioengineering and Biotechnology

(The TQCC of Frontiers in Bioengineering and Biotechnology is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-05-01 to 2023-05-01.)
Synthesis of Silver Nanoparticles Mediated by Fungi: A Review300
Cellulose Biomaterials for Tissue Engineering238
3D and 4D Printing of Polymers for Tissue Engineering Applications226
Microbial Proteases Applications219
Recent Developments in Bioprocessing of Recombinant Proteins: Expression Hosts and Process Development215
A Perspective on Polylactic Acid-Based Polymers Use for Nanoparticles Synthesis and Applications210
Nanotechnology in Plant Science: To Make a Long Story Short178
Use of Nanoparticles in Tissue Engineering and Regenerative Medicine169
Enzymatic Modifications of Chitin, Chitosan, and Chitooligosaccharides162
Biomaterials and Nanotherapeutics for Enhancing Skin Wound Healing162
Engineering Organoid Vascularization160
Challenges With the Development of Biomaterials for Sustainable Tissue Engineering151
The Use of Microalgae for Coupling Wastewater Treatment With CO2 Biofixation141
Modern Trends for Peripheral Nerve Repair and Regeneration: Beyond the Hollow Nerve Guidance Conduit132
New Applications of Synthetic Biology Tools for Cyanobacterial Metabolic Engineering129
Titanium–Tissue Interface Reaction and Its Control With Surface Treatment126
Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome122
Methods for Segmentation and Classification of Digital Microscopy Tissue Images117
Bacterial Valorization of Lignin: Strains, Enzymes, Conversion Pathways, Biosensors, and Perspectives98
Innovative Tools for Mechanobiology: Unraveling Outside-In and Inside-Out Mechanotransduction97
Nano-Enhanced Drug Delivery and Therapeutic Ultrasound for Cancer Treatment and Beyond97
Determination of Corneal Biomechanical Behavior in-vivo for Healthy Eyes Using CorVis ST Tonometry: Stress-Strain Index97
Multiple and Promising Applications of Strontium (Sr)-Containing Bioactive Glasses in Bone Tissue Engineering96
Advances and Current Challenges in Intestinal in vitro Model Engineering: A Digest96
Development of L-Asparaginase Biobetters: Current Research Status and Review of the Desirable Quality Profiles96
Plants Developed by New Genetic Modification Techniques—Comparison of Existing Regulatory Frameworks in the EU and Non-EU Countries91
A Robust Longitudinal Co-culture of Obligate Anaerobic Gut Microbiome With Human Intestinal Epithelium in an Anoxic-Oxic Interface-on-a-Chip88
Biomethane Production From Lignocellulose: Biomass Recalcitrance and Its Impacts on Anaerobic Digestion86
Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro86
NanoBRET: The Bright Future of Proximity-Based Assays86
A Random Forest Sub-Golgi Protein Classifier Optimized via Dipeptide and Amino Acid Composition Features85
Recent Advances in Nanomaterials-Based Chemo-Photothermal Combination Therapy for Improving Cancer Treatment83
Collagen-Based Tissue Engineering Strategies for Vascular Medicine82
A Review of Structural and Biomechanical Changes in the Cornea in Aging, Disease, and Photochemical Crosslinking81
Corneal Repair and Regeneration: Current Concepts and Future Directions79
Photodynamic Therapy Based on Graphene and MXene in Cancer Theranostics78
Gene-Expressing Liposomes as Synthetic Cells for Molecular Communication Studies76
Cell Cytometry: Review and Perspective on Biotechnological Advances76
Encapsulation and Controlled Release of Resveratrol Within Functionalized Mesoporous Silica Nanoparticles for Prostate Cancer Therapy75
Peptide-Based Functional Biomaterials for Soft-Tissue Repair74
Applications of Iron Oxide-Based Magnetic Nanoparticles in the Diagnosis and Treatment of Bacterial Infections74
Bioproducts From Euglena gracilis: Synthesis and Applications71
3D-Printed PCL/PPy Conductive Scaffolds as Three-Dimensional Porous Nerve Guide Conduits (NGCs) for Peripheral Nerve Injury Repair71
Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles68
Overcoming Physiological Barriers to Nanoparticle Delivery—Are We There Yet?65
Genetically Engineered Crops: Importance of Diversified Integrated Pest Management for Agricultural Sustainability65
Future Trends in Synthetic Biology—A Report64
Exploring the Potential of Cell-Free Protein Synthesis for Extending the Abilities of Biological Systems64
Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture63
Cell Encapsulation Within Alginate Microcapsules: Immunological Challenges and Outlook62
Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs61
Non-invasive Production of Multi-Compartmental Biodegradable Polymer Microneedles for Controlled Intradermal Drug Release of Labile Molecules59
Physical and Antibacterial Properties of Peppermint Essential Oil Loaded Poly (ε-caprolactone) (PCL) Electrospun Fiber Mats for Wound Healing59
Integrative Bioinformatics Approaches to Map Potential Novel Genes and Pathways Involved in Ovarian Cancer58
Impaired Wound Healing of Alveolar Lung Epithelial Cells in a Breathing Lung-On-A-Chip57
Exploring Instructive Physiological Signaling with the Bioelectric Tissue Simulation Engine57
Ultra-Low-Cost 3D Bioprinting: Modification and Application of an Off-the-Shelf Desktop 3D-Printer for Biofabrication56
Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model56
Enzymatic Bioremediation of Organophosphate Compounds—Progress and Remaining Challenges55
Nanomedicine Approaches for the Pulmonary Treatment of Cystic Fibrosis54
Normalization Methods for the Analysis of Unbalanced Transcriptome Data: A Review54
A Clostridium Group IV Species Dominates and Suppresses a Mixed Culture Fermentation by Tolerance to Medium Chain Fatty Acids Products54
AOPs-SVM: A Sequence-Based Classifier of Antioxidant Proteins Using a Support Vector Machine53
Cytotoxicity-Related Bioeffects Induced by Nanoparticles: The Role of Surface Chemistry52
Hazard Assessment of Polymeric Nanobiomaterials for Drug Delivery: What Can We Learn From Literature So Far52
Sequential Co-immobilization of Enzymes in Metal-Organic Frameworks for Efficient Biocatalytic Conversion of Adsorbed CO2 to Formate52
Biosensors for On-Farm Diagnosis of Mastitis51
Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 201949
Three Dimensional Printing Bilayer Membrane Scaffold Promotes Wound Healing49
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients – A Bioinformatics Approach49
An EU Perspective on Biosafety Considerations for Plants Developed by Genome Editing and Other New Genetic Modification Techniques (nGMs)49
Metabolic Engineering and Synthetic Biology: Synergies, Future, and Challenges48
Classifying Promoters by Interpreting the Hidden Information of DNA Sequences via Deep Learning and Combination of Continuous FastText N-Grams48
Raman Spectroscopy: Guiding Light for the Extracellular Matrix48
Small Caliber Compliant Vascular Grafts Based on Elastin-Like Recombinamers for in situ Tissue Engineering48
Perspective on Pulsed Electric Field Treatment in the Bio-based Industry48
Improving Reproducibility in Synthetic Biology47
A Microfluidic System for Studying the Effects of Disturbed Flow on Endothelial Cells47
Polymeric Approaches to Reduce Tissue Responses Against Devices Applied for Islet-Cell Encapsulation47
Cytocompatible and Anti-bacterial Adhesion Nanotextured Titanium Oxide Layer on Titanium Surfaces for Dental and Orthopedic Implants47
Investigation of the Antibacterial Activity and in vivo Cytotoxicity of Biogenic Silver Nanoparticles as Potent Therapeutics46
Nanotheranostics Targeting the Tumor Microenvironment46
Functionalising Collagen-Based Scaffolds With Platelet-Rich Plasma for Enhanced Skin Wound Healing Potential44
Biological Parts for Kluyveromyces marxianus Synthetic Biology44
A Direct Comparison of Biplanar Videoradiography and Optical Motion Capture for Foot and Ankle Kinematics43
Enzymatic Degradation of Biofilm by Metalloprotease From Microbacterium sp. SKS1043
Perspectives on Harmful Algal Blooms (HABs) and the Cyberbiosecurity of Freshwater Systems43
Addressing Patient Specificity in the Engineering of Tumor Models43
Molecular Modeling for Nanomaterial–Biology Interactions: Opportunities, Challenges, and Perspectives43
Systematic Characterization of Circular RNA-Associated CeRNA Network Identified Novel circRNA Biomarkers in Alzheimer's Disease42
Maximizing the Efficiency of Vanillin Production by Biocatalyst Enhancement and Process Optimization42
Deep Learning With Sampling in Colon Cancer Histology42
Engineering Strategies in Microorganisms for the Enhanced Production of Squalene: Advances, Challenges and Opportunities42
Engineered Cell-Based Therapeutics: Synthetic Biology Meets Immunology41
Using Bioactive Glasses in the Management of Burns41
Inflammation and Bone Repair: From Particle Disease to Tissue Regeneration40
Occurrence of Soil Fungi in Antarctic Pristine Environments40
Composite Hydrogels in Three-Dimensional in vitro Models40
Bioactivation Routes of Gelatin-Based Scaffolds to Enhance at Nanoscale Level Bone Tissue Regeneration40
Biomechanical Investigation of Disturbed Hemodynamics-Induced Tissue Degeneration in Abdominal Aortic Aneurysms Using Computational and Experimental Techniques40
Drug Delivery From Polymer-Based Nanopharmaceuticals—An Experimental Study Complemented by Simulations of Selected Diffusion Processes39
Optically Active Nanomaterials for Bioimaging and Targeted Therapy39
Identification of Prognostic and Metastatic Alternative Splicing Signatures in Kidney Renal Clear Cell Carcinoma38
3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite38
Statistical Shape Modeling of Skeletal Anatomy for Sex Discrimination: Their Training Size, Sexual Dimorphism, and Asymmetry38
Biological Response to Carbon-Family Nanomaterials: Interactions at the Nano-Bio Interface38
Scalable 3D Printed Molds for Human Tissue Engineered Skeletal Muscle38
Magnetic Separation in Bioprocessing Beyond the Analytical Scale: From Biotechnology to the Food Industry38
Surface Modification of Aliphatic Polyester to Enhance Biocompatibility38
Advances in Using Hansenula polymorpha as Chassis for Recombinant Protein Production37
Staining Invariant Features for Improving Generalization of Deep Convolutional Neural Networks in Computational Pathology37
Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing37
Production of Melanins With Recombinant Microorganisms37
Microalgal Protein Extraction From Chlorella vulgaris FSP-E Using Triphasic Partitioning Technique With Sonication37
Neural Lineage Differentiation From Pluripotent Stem Cells to Mimic Human Brain Tissues37
Advantages of Hydrogel-Based 3D-Printed Enzyme Reactors and Their Limitations for Biocatalysis36
Vascular Niche in Lung Alveolar Development, Homeostasis, and Regeneration36
Long-Term Behavior of Defined Mixed Cultures of Geobacter sulfurreducens and Shewanella oneidensis in Bioelectrochemical Systems36
Laminin-Coated Electrospun Regenerated Silk Fibroin Mats Promote Neural Progenitor Cell Proliferation, Differentiation, and Survival in vitro36
Factors Influencing Recombinant Protein Secretion Efficiency in Gram-Positive Bacteria: Signal Peptide and Beyond35
Mechanisms of Adverse Local Tissue Reactions to Hip Implants35
A Systematic Review and Meta-Analysis of Clinical Effectiveness and Safety of Hydrogel Dressings in the Management of Skin Wounds35
The Extracellular Matrix and Biocompatible Materials in Glioblastoma Treatment35
Beyond the Present Constraints That Prevent a Wide Spread of Tissue Engineering and Regenerative Medicine Approaches35
Regulatory Status of Genome-Edited Organisms Under the Japanese Cartagena Act35
Decellularized Adipose Tissue Hydrogel Promotes Bone Regeneration in Critical-Sized Mouse Femoral Defect Model34
Fibronectin Functionalized Electrospun Fibers by Using Benign Solvents: Best Way to Achieve Effective Functionalization33
Biomechanical Impact of the Sclera on Corneal Deformation Response to an Air-Puff: A Finite-Element Study33
Technology Advancements in Blood Coagulation Measurements for Point-of-Care Diagnostic Testing33
Three-Layered Silk Fibroin Tubular Scaffold for the Repair and Regeneration of Small Caliber Blood Vessels: From Design to in vivo Pilot Tests33
Multi-Factorial-Guided Media Optimization for Enhanced Biomass and Lipid Formation by the Oleaginous Yeast Cutaneotrichosporon oleaginosus33
Specifications for Innovative, Enabling Biomaterials Based on the Principles of Biocompatibility Mechanisms33
Synovium-Derived Mesenchymal Stem Cell Transplantation in Cartilage Regeneration: A PRISMA Review of in vivo Studies33