Clinical and Molecular Hepatology

Papers
(The TQCC of Clinical and Molecular Hepatology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Preface387
Unveiling etiology-specific blood biomarkers in hepatocellular carcinoma: A gateway to personalized medicine: Editorial on “Multiomics profiling of buffy coat and plasma unveils etiology-specific sign313
Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future230
Approaches to quantifying hepatitis B virus covalently closed circular DNA198
Cardiovascular risk of tenofovir disoproxil fumarate or tenofovir alafenamide in patients with chronic hepatitis B: More questions than an answer193
Baveno VI-SSM was able to stratify the risk of portal hypertension-related events in patients with HBV-related cirrhosis159
Correspondence to editorial on “Prevalence of clinically significant liver fibrosis in the general population: A systematic review and meta-analysis”107
Comment: Non-invasive prediction of post-sustained virological response hepatocellular carcinoma in hepatitis C virus105
Downregulation of the MARC1 p.A165 risk allele reduces hepatocyte lipid content by increasing beta-oxidation85
From nonalcoholic steatohepatitis, metabolic dysfunction-associated fatty liver disease, to steatotic liver disease: Updates of nomenclature and impact on clinical trials76
Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma in the era of chemo-diversity73
Comparison of four histological scoring systems for autoimmune hepatitis to improve diagnostic sensitivity73
Carvedilol to prevent hepatic decompensation of cirrhosis in patients with clinically significant portal hypertension stratified by new non-invasive model (CHESS2306)70
Nonalcoholic fatty liver disease-based risk prediction of adverse pregnancy outcomes: Ready for prime time?70
Anti-fibrotic treatments for chronic liver diseases: The present and the future69
U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases62
Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study60
Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial58
Comprehensive analysis of transcriptomic biomarkers for predicting response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma56
Reply to authors’ reply: “Baveno VI-SSM stratifies the risk of portal hypertension-related events in patients with HBV-related cirrhosis”53
Equivalent prevalence and progression of chronic kidney disease in non-alcoholic fatty liver disease and metabolic dysfunction-associated steatotic liver disease50
Reconsidering treatment indications for chronic hepatitis B: Insights from the TORCH-B roll-over study: Editorial on “Antiviral therapy for chronic hepatitis B with mildly elevated aminotransferase: A49
Current burden of steatotic liver disease and fibrosis among adults in the United States, 2017–202349
Correspondence to editorial on “Core indicators related to the elimination of hepatitis B and C virus infection in South Korea: A nationwide study”49
Radiogenomics of intrahepatic cholangiocarcinoma predicts immunochemotherapy response and identifies therapeutic target49
The role of SPP1 in MASLD pathogenesis: Therapeutic insights into ursolic acid’s mechanisms of action: Correspondence to editorial on “Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 c46
Leaky gut-derived tumor necrosis factor-α causes sarcopenia in patients with liver cirrhosis45
Toward hepatitis C virus elimination using artificial intelligence44
Liver organoids: Current advances and future applications for hepatology43
Current evidence and the potential role of proton beam therapy for hepatocellular carcinoma42
Carbon Ion Radiotherapy in the Treatment of Hepatocellular Carcinoma42
Hepatocytes infected with hepatitis C virus change immunological features in the liver microenvironment40
Personalized approaches to the treatment of hepatocellular carcinoma using immune checkpoint inhibitors: Editorial on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunothe39
Treatment response to nucleos(t)ide analogs in chronic hepatitis B with mildly elevated alanine aminotransferase: Letter to the editor on “Antiviral therapy for chronic hepatitis B with mildly elevate39
A decade of liver organoids: Advances in disease modeling37
Deep learning-based prediction of molecular cancer biomarkers from tissue slides: A new tool for precision oncology37
Predicting decompensation risk in compensated HBV cirrhosis: Eternal sunshine for a spotless mind?36
Artificial intelligence predicts direct-acting antivirals failure among hepatitis C virus patients: A nationwide hepatitis C virus registry program35
Chronic hepatitis B, extrahepatic malignancies and the use of antiviral drugs35
Hard-to-treat autoimmune hepatitis and primary biliary cholangitis: The dawn of a new era of pharmacological treatment35
Correspondence to letter to the editor on “Prevalence of clinically significant liver fibrosis in the general population: A systematic review and meta-analysis”35
What is new in the 2024 Chinese guidelines for fatty liver disease?34
The independent effect of exercise on biopsy proven non-alcoholic fatty liver disease: A systematic review34
Correspondence on Letter regarding “Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?”34
A crystal ball to forecast treatment responsiveness in nonalcoholic fatty liver disease34
Reply to correspondence on “Novel role of MHC class II transactivator in hepatitis B virus replication and viral counteraction”34
Leukocyte telomere shortening in metabolic dysfunction-associated steatotic liver disease and all-cause/cause-specific mortality34
Reply to: “Evaluation of the histological scoring systems of autoimmune hepatitis: A significant step towards the optimization of clinical diagnosis”33
Non-alcoholic fatty liver disease and the risk of dementia: A meta-analysis of cohort studies32
Core protein inhibitors: Opportunities and challenges at the forefront of hepatitis B cure: Editorial on “Phase 1 trial of the safety, pharmacokinetics, and antiviral activity of EDP-514 in untreated 32
Correspondence to editorial on “Genetically-modified, redirected T cells target hepatitis B surface antigen-positive hepatocytes and hepatocellular carcinoma lesions in a clinical setting”32
Stroma-tology: Predicting recurrence in cholangiocarcinoma: Editorial on “Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma”32
Conventional and machine learning-based risk scores for patients with early-stage hepatocellular carcinoma31
Non-alcoholic fatty liver disease and risk of dementia: Unmet need for a pooled analysis of cohort studies30
Hepatocellular carcinoma incidence is decreasing in Korea but increasing in the very elderly30
Adverse impact of metabolic dysfunction on fibrosis regression following direct-acting antiviral therapy: A multicenter study for chronic hepatitis C30
KASL clinical practice guidelines: Management of nonalcoholic fatty liver disease29
Extrahepatic malignancies and antiviral drugs for chronic hepatitis B: A nationwide cohort study29
Causes and risk profiles of mortality among individuals with nonalcoholic fatty liver disease29
Immunopathogenesis of liver fibrosis in steatotic liver disease28
Hepatocellular carcinoma surveillance in non-alcoholic fatty liver disease – who and how?27
Correspondence to editorial on “Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment”27
Correspondence to editorial on “Sorafenib vs. Lenvatinib in advanced hepatocellular carcinoma after atezolizumab/bevacizumab failure: A real-world study”27
Reappraisal of transarterial radioembolization for liver-confined hepatocellular carcinoma with portal vein tumor thrombosis: Editorial on “Transarterial radioembolization versus tyrosine kinase inhib26
The urgent need for multidisciplinary approaches in managing alcohol-associated liver disease: Editorial on “The prognostic impact of psychiatric intervention on alcohol-associated liver disease: The 25
Outcomes after liver transplantation in Korea: Incidence and risk factors from Korean transplantation registry25
Metabolic Health in Antiviral Era of Chronic Hepatitis B24
Insertion of a transjugular intrahepatic portosystemic shunt leads to sustained reversal of systemic inflammation in patients with decompensated liver cirrhosis24
Identification of signature gene set as highly accurate determination of metabolic dysfunction-associated steatotic liver disease progression24
New biomarkers of hepatitis B virus (HBV) infection: HBV RNA and HBV core-related antigen, new kids on the block?24
Interaction between sarcopenia and nonalcoholic fatty liver disease24
Management of hepatocellular carcinoma in China: Seeking common grounds while reserving differences23
Association of Visceral Fat Obesity, Sarcopenia, and Myosteatosis with Non-Alcoholic Fatty Liver Disease without Obesity23
Acute-on-chronic liver failure: Terminology, mechanisms and management23
Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF- κB signaling pathways22
Development of risk scores for prognosis prediction among patients with early-stage hepatocellular carcinoma22
Global incidence and prevalence of nonalcoholic fatty liver disease22
Presence of liver fibrosis in chronic hepatitis B patients with varying serum hepatitis B virus DNA levels: Letter to the editor on “Non-linear association between liver fibrosis scores and viral load22
Mendelian randomization does not support the effects of G CSF on decompensated liver disease22
Gut microbiome and metabolome signatures in liver cirrhosis-related complications21
Assessment of the postoperative prognosis in patients with hepatocellular carcinoma using vibration-controlled transient elastography: A systemic review and meta-analysis21
Clinical significance of the discrepancy between radiological findings and biochemical responses in atezolizumab plus bevacizumab for hepatocellular carcinoma21
Correspondence to Editorial on “Switching to Besifovir in Patients with Chronic Hepatitis B Receiving Tenofovir Disoproxil Fumarate: A Randomized Trial”21
Macrophage ATG16L1: Potential candidate for metabolic dysfunction-associated steatohepatitis treatment: Editorial on “Macrophage ATG16L1 expression suppresses metabolic dysfunction-associated steatohe21
Can SAFE score be utilized as a universal hepatocellular carcinoma prediction score? Editorial on “High SAFE scores predict hepatocellular carcinoma in viral and non-viral hepatitis and metabolic dys21
A new Korean nomenclature for steatotic liver disease21
Correspondence on Letter 2 regarding “Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma”21
Transarterial chemoembolization for hepatocellular carcinoma: 2023 Expert consensus-based practical recommendations of the Korean Liver Cancer Association20
Effect of moderate-to-severe hepatic steatosis on neutralising antibody response among BNT162b2 and CoronaVac recipients20
Three heads are better than two: Hepatitis B core-related antigen as a new predictor of hepatitis B virus-related hepatocellular carcinoma20
Correspondence to editorial on “Multiomics profiling of buffy coat and plasma unveils etiology-specific signatures in hepatocellular carcinoma”20
Optimal cut-offs of vibration-controlled transient elastography and magnetic resonance elastography in diagnosing advanced liver fibrosis in patients with nonalcoholic fatty liver disease: A systemati19
Letter: cervicocerebral atherosclerosis and its hepatic and coronary risk factors in patients with liver cirrhosis19
Changes in the epidemiology and management of bacterial infections in cirrhosis19
Chemoembolization combined with radiofrequency ablation is the best option for the local treatment of early hepatocellular carcinoma?19
The imitator of immune-tolerant chronic hepatitis B: A killer in disguise19
Regulation of Hepatitis B Virus cccDNA by Metabolic Pathways19
Antiviral therapy for chronic hepatitis B with mildly elevated aminotransferase: A rollover study from the TORCH-B trial18
A complement to epigenetics in metabolic dysfunction-associated steatotic liver disease: Editorial on “DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dy18
Screening strategy for non-alcoholic fatty liver disease17
Decreasing performance of HCC prediction models during antiviral therapy for hepatitis B: what else to keep in mind: Editorial on “Hepatocellular carcinoma prediction model performance decreases with 17
Factors associated with unrecognized cirrhosis in patients with hepatocellular carcinoma17
KASL clinical practice guidelines for management of chronic hepatitis B16
Neuropilins as potential biomarkers in hepatocellular carcinoma: a systematic review of basic and clinical implications16
Hepatitis B core-related antigen dynamics and risk of subsequent clinical relapses after nucleos(t)ide analog cessation16
2022 KLCA-NCC Korea practice guidelines for the management of hepatocellular carcinoma16
The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults16
Correspondence on Editorial regarding “Baveno-VII criteria to predict decompensation and initiate non-selective beta-blocker in compensated advanced chronic liver disease patients”16
Risk assessment of hepatitis B virus-related hepatocellular carcinoma development using vibration-controlled transient elastography: Systematic review and meta-analysis16
Non-alcoholic fatty liver disease increases risk of carotid atherosclerosis and ischemic stroke: An updated meta-analysis with 135,602 individuals16
The effect of moderate alcohol consumption on nonalcoholic fatty liver disease15
Evidence-based hyponatremia management in liver disease15
JCAD, a new potential therapeutic target in cholestatic liver disease15
Incretin-based therapy in the management of metabolic dysfunction-associated steatotic liver disease (MASLD): one piece of the puzzle: Editorial on “Comparison of glucagon-like peptide-1 receptor agon15
Imaging diagnosis of hepatocellular carcinoma: Future directions with special emphasis on hepatobiliary magnetic resonance imaging and contrast-enhanced ultrasound15
Correspondence to letter to the editor on “Genomic biomarkers to predict response to atezolizumab plus bevacizumab immunotherapy in hepatocellular carcinoma: Insights from the IMbrave150 trial”15
Impact of components of metabolic syndrome on long-term outcomes of CHB with nucleos(t)ide analogue treatment15
Cervicocerebral atherosclerosis and its hepatic and coronary risk factors in patients with liver cirrhosis14
Sex-specific associations of metabolic dysfunction-associated steatotic liver disease with cardiovascular outcomes14
Statin and aspirin for chemoprevention of hepatocellular carcinoma: Time to use or wait further?14
A non-invasive risk stratification tool for hepatitis B-related liver cirrhosis: the Baveno VI-SSM combined model.14
Baveno VII criteria to predict decompensation in compensated advanced chronic liver disease: Still some shades of grey14
Correspondence to editorial on “Optimal cut-offs of vibration-controlled transient elastography and magnetic resonance elastography in diagnosing advanced liver fibrosis in patients with nonalcoholic 13
Roles of X-box binding protein 1 in liver pathogenesis13
Efficacy, safety, and pharmacokinetics of capsid assembly modulator linvencorvir plus standard of care in chronic hepatitis B patients13
Correspondence to editorial on “Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma”13
Aberrant fragmentomic features of circulating cell-free mitochondrial DNA enable early detection and prognosis prediction of hepatocellular carcinoma13
Update on liver disease management during the pandemic of coronavirus disease 2019 (COVID-19): 2021 KASL guideline13
From past to pandemic: Health disparities in US hepatobiliary cancer mortality before and during COVID-19: Editorial on “Burden of mortality from hepatocellular carcinoma and biliary tract cancers by 13
Clinical impact of five cardiometabolic risk factors in metabolic dysfunction-associated steatotic liver disease (MASLD): Insights into regional and ethnic differences13
Impact of nationwide hepatocellular carcinoma surveillance on the prognosis in patients with chronic liver disease12
Correspondence to editorial on “Safety and efficacy of HK-660S in patients with primary sclerosing cholangitis: A randomized double-blind phase 2a trial”12
Management of refractory ascites12
Surgical resection versus ablation for early hepatocellular carcinoma: The debate is still open12
Severity of microvascular invasion does matter in hepatocellular carcinoma prognosis: Editorial on “Classification of microvascular invasion of hepatocellular carcinoma: correlation with prognosis and12
Universal self-testing as a cost-effective weapon to eliminate hepatitis C virus in the Republic of Korea: Editorial on “Self-testing strategy to eliminate hepatitis C as per World Health Organization11
Recent advances in nonalcoholic fatty liver disease metabolomics11
Intrahepatic cholangiocarcinoma: Tumour heterogeneity and its clinical relevance11
Global inequality in the burden of hepatitis B from 1990 to 2021: Findings from the global burden of disease study 2021: Letter to the editor on “Comprehensive approach to controlling chronic hepatiti11
Non-alcoholic fatty liver disease: Definition and subtypes11
Prediction models of hepatocellular carcinoma recurrence after liver transplantation: A comprehensive review11
Clinical practice guidelines and real-life practice in hepatocellular carcinoma: A Taiwan perspective11
Hepatocellular carcinoma surveillance in patients with non-alcoholic fatty liver disease11
Effects of interleukin-17 inhibitors on hepatic fibrosis index in patients with psoriasis and metabolic dysfunction-associated fatty liver disease: Directed acyclic graphs11
Erratum to ‘Is liver biopsy essential to identifying the immune tolerant phase of chronic hepatitis B?’ [Clin Mol Hepatol 2023;29:367-370]10
The impact of ischemia-free liver transplantation on improving the prognosis of recipients using functionally marginal liver grafts: Editorial on “Ischemia-free liver transplantation improves the prog10
History and future of hepatitis B virus control in South Korea10
The use of transient elastography for predicting hepatocellular carcinoma in chronic hepatitis B patients: Editorial on “Risk assessment of hepatitis B virus-related hepatocellular carcinoma developme10
Letter regarding “Waiting for the changes after the adoption of steatotic liver disease”10
Correspondence to editorial on “Hepatocellular carcinoma prediction model performance decreases with long-term antiviral therapy in chronic hepatitis B patients”10
Contemporary awareness of viral hepatitis between 2012 and 2022 among Korean adults10
Letter regarding “Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF-κB signaling pathways”10
Association of nonalcoholic fatty liver disease with incident dementia later in life among elderly adults10
Correspondence to letter to the editor 1 on “Evolutionary changes in metabolic dysfunction-associated steatotic liver disease and risk of hepatocellular carcinoma: A nationwide cohort study”10
Congratulatory remarks9
Gut microbiota-mediated gut-liver axis: a breakthrough point for understanding and treating liver cancer9
Longitudinal profile of plasma pregenomic RNA in patients with chronic hepatitis B infection on long-term nucleoside analogues and its interaction with clinical parameters9
Impact of fatty liver on long-term outcomes in chronic hepatitis B: a systematic review and matched analysis of individual patient data meta-analysis9
Acute hepatitis C virus infection: clinical update and remaining challenges9
Global prevalence of metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis9
Elimination of viral hepatitis: How far are we?: Editorial on “Core indicators related to the elimination of hepatitis B and C virus infection in South Korea: A nationwide study”8
Tacrolimus levels and variability in CKD and ESRD risk post-liver transplant: Letter to the editor on “Optimal tacrolimus levels for reducing CKD risk and the impact of intrapatient variability on CKD8
Hepatorenal syndrome: Current concepts and future perspectives8
Correspondence on Letter regarding “Both liver parenchymal and non-parenchymal cells express JCAD proteins under various circumstances”8
Dyslipidemia in chronic hepatitis B patients on tenofovir alafenamide: Facts and puzzles8
Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma8
Transarterial radioembolization versus tyrosine kinase inhibitor in hepatocellular carcinoma with portal vein thrombosis8
Optimal tacrolimus levels for reducing CKD risk and the impact of intrapatient variability on CKD and ESRD development following liver transplantation8
Correspondence to editorial on “GOLM1 promotes cholesterol gallstone formation via ABCG5-mediated cholesterol efflux in MASH livers”8
Chronic hepatitis B with concurrent metabolic dysfunction-associated fatty liver disease: Challenges and perspectives8
The latest global burden of liver cancer: A past and present threat8
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