JPAD-Journal of Prevention of Alzheimers Disease

Article	Citations
Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease	138
The Epidemiology of Alzheimer’s Disease Modifiable Risk Factors and Prevention	83
Diagnosis of Early Alzheimer’s Disease: Clinical Practice in 2021	75
Aducanumab: Appropriate Use Recommendations	53
Lecanemab: Appropriate Use Recommendations	46
Aducanumab: Appropriate Use Recommendations Update	32
Senolytic Therapy to Modulate the Progression of Alzheimer’s Disease (SToMP-AD): A Pilot Clinical Trial	22
Current State of Self-Administered Brief Computerized Cognitive Assessments for Detection of Cognitive Disorders in Older Adults: A Systematic Review	22
Effects of Folic Acid and Vitamin B12 Supplementation on Cognitive Impairment and Inflammation in Patients with Alzheimer’s Disease: A Randomized, Single-Blinded, Placebo-Controlled Trial	19
Donanemab (LY3002813) Phase 1b Study in Alzheimer’s Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging	19
Detection and Management of Amyloid-Related Imaging Abnormalities in Patients with Alzheimer’s Disease Treated with Anti-Amyloid Beta Therapy	17
Blood Biomarkers from Research Use to Clinical Practice: What Must Be Done? A Report from the EU/US CTAD Task Force	14
Intranasal Insulin Reduces White Matter Hyperintensity Progression in Association with Improvements in Cognition and CSF Biomarker Profiles in Mild Cognitive Impairment and Alzheimer’s Disease	14
Socioeconomic Status and Risks of Cognitive Impairment and Dementia: A systematic Review and Meta-Analysis of 39 Prospective Studies	11
Establishing Clinically Meaningful Change on Outcome Assessments Frequently Used in Trials of Mild Cognitive Impairment Due to Alzheimer’s Disease	10
Tackling a Major Deficiency of Diversity in Alzheimer’s Disease Therapeutic Trials: An CTAD Task Force Report	9
The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled Trial	8
ITEM-LEVEL INVESTIGATION OF PARTICIPANT AND STUDY PARTNER REPORT ON THE COGNITIVE FUNCTION INDEX FROM THE A4 STUDY SCREENING DATA	7
Association of Subjective Cognitive Decline with Risk of Cognitive Impairment and Dementia: A Systematic Review and Meta-Analysis of Prospective Longitudinal Studies	7
Buntanetap, a Novel Translational Inhibitor of Multiple Neurotoxic Proteins, Proves to Be Safe and Promising in Both Alzheimer’s and Parkinson’s Patients	7
Major Cost Drivers in Assessing the Economic Burden of Alzheimer’s Disease: A Structured, Rapid Review	6
Programmed Death of Microglia in Alzheimer’s Disease: Autophagy, Ferroptosis, and Pyroptosis	6
The Scottish Brain Health Service Model: Rationale and Scientific Basis for a National Care Pathway of Brain Health Services in Scotland	6
ACU193, a Monoclonal Antibody that Selectively Binds Soluble Aß Oligomers: Development Rationale, Phase 1 Trial Design, and Clinical Development Plan	6
Amyloid and APOE Status of Screened Subjects in the Elenbecestat MissionAD Phase 3 Program	6

Effects of Mindfulness-Based Tai Chi Chuan on Physical Performance and Cognitive Function among Cognitive Frailty Older Adults: A Six-Month Follow-Up of a Randomized Controlled Trial	6
The Future of AD Clinical Trials with the Advent of Anti-Amyloid Therapies: An CTAD Task Force Report	6
Antihypertensive Agents and Incident Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Observational Studies	5
Aging, Senescence, and Dementia	5
Living Environment, Built Environment and Cognitive Function among Older Chinese Adults: Results from a Cross-Sectional Study	5
Childhood Secondhand Smoke Exposure and Risk of Dementia, Alzheimer’s Disease and Stroke in Adulthood: A Prospective Cohort Study	5
Representation of Racial and Ethnic Minority Populations in Dementia Prevention Trials: A Systematic Review	5
POSTERS 14th Conference Clinical Trials Alzheimer’s Disease, November 9-12, 2021, Boston, USA	5
Blood Derived Amyloid Biomarkers for Alzheimer’s Disease Prevention	4
Effects of Non-Invasive Brain Stimulation on Alzheimer’s Disease	4
Tauroursodeoxycholic Acid Attenuates Diet-Induced and Age-Related Peripheral Endoplasmic Reticulum Stress and Cerebral Amyloid Pathology in a Mouse Model of Alzheimer’s Disease	4
Immunotherapy for Alzheimer’s Disease: Current Scenario and Future Perspectives	4
Using Digital Tools to Advance Alzheimer’s Drug Trials During a Pandemic: The EU/US CTAD Task Force	4
Environmental Distractions during Unsupervised Remote Digital Cognitive Assessment	4
Sex Moderates the Association between Frailty and Mild Behavioral Impairment	4
The Effects of Dual-Task Training on Cognitive and Physical Functions in Older Adults with Cognitive Impairment; A Systematic Review and Meta-Analysis	4
Sensitivity of the Preclinical Alzheimer’s Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheimer’s Disease -Atabece	4
Elevated Blood Homocysteine and Risk of Alzheimer’s Dementia: An Updated Systematic Review and Meta-Analysis Based on Prospective Studies	4
Digital Screening for Cognitive Impairment – A Proof of Concept Study	4
Cognitive Digital Biomarkers from Automated Transcription of Spoken Language	4
Cerebral Phospho-Tau Acts Synergistically with Soluble Aβ42 Leading to Mild Cognitive Impairment in AAV-AD Rats	4
Clinical Trial Endpoints and Their Clinical Meaningfulness in Early Stages of Alzheimer’s Disease	4
‘Time Saved’ As a Demonstration of Clinical Meaningfulness and Illustrated Using the Donanemab TRAILBLAZER-ALZ Study Findings	4
Effectiveness of Physical Exercise on Alzheimer’s disease. A Systematic Review	4
Communicating Personal Risk Profiles of Alzheimer’s Disease to Older Adults: A Pilot Trial	4
Association of a MIND Diet with Brain Structure and Dementia in a French Population	4
Aducanumab Trials EMERGE But Don’t ENGAGE	4
The ‘Aducanumab Story’: Will the Last Chapter Spell the End of the ‘Amyloid Hypothesis’ or Mark a New Beginning?	3
Everyday Functioning and Entorhinal and Inferior Temporal Tau Burden in Cognitively Normal Older Adults	3
What Matters to Patients with Alzheimer’s Disease and Their Care Partners? Implications for Understanding the Value of Future Interventions	3
Editorial: What Are the Remaining Challenges before Blood-Based Biomarkers for Alzheimer’s Disease Can Be Used in Clinical Practice?	3
The Association between Peanut and Peanut Butter Consumption and Cognitive Function among Community-Dwelling Older Adults	3
Platform Trials to Expedite Drug Development in Alzheimer’s Disease: A Report from the EU/US CTAD Task Force	3
Early-Onset Subgroup of Type 2 Diabetes and Risk of Dementia, Alzheimer’s disease and Stroke: A Cohort Study	3
Multimodal Preventive Trial for Alzheimer’s Disease: MIND-ADmini Pilot Trial Study Design and Progress	3
Recruitment of Older African Americans in Alzheimer’s Disease Clinical Trials Using a Community Education Approach	3
Salivary Alpha-Amylase Activity and Mild Cognitive Impairment among Japanese Older Adults: The Toon Health Study	3
Can We Use Blood Biomarkers as Entry Criteria and for Monitoring Drug Treatment Effects in Clinical Trials? A Report from the EU/US CTAD Task Force	3
The Role of Thyroid Dysfunction in Alzheimer’s Disease: A Systematic Review and Meta-Analysis	3
Geniposidic Acid Confers Neuroprotective Effects in a Mouse Model of Alzheimer’s Disease through Activation of a PI3K/AKT/GAP43 Regulatory Axis	3
Disease Burden and Attributable Risk Factors of Alzheimer’s Disease and Dementia in China from 1990 to 2019	3
Aducanumab: Appropriate Use Recommendations	3
Safety, Tolerability, Pharmacokinetics and Quantitative Electroencephalography Assessment of ACD856, a Novel Positive Allosteric Modulator of Trk-Receptors Following Multiple Doses in Healthy Subjects	3
The Effect of Multidomain Interventions on Global Cognition, Symptoms of Depression and Apathy – A Pooled Analysis of Two Randomized Controlled Trials	3
Digital Therapeutics for MCI and Alzheimer’s disease: A Regulatory Perspective - Highlights From The Clinical Trials on Alzheimer’s Disease conference (CTAD)	3
Mechanisms Underlying Non-Pharmacological Dementia Prevention Strategies: A Translational Perspective	2
Evidence-Based Tools for Dietary Assessments in Nutrition Epidemiology Studies for Dementia Prevention	2
Clinical Research Investigating Alzheimer’s Disease in China: Current Status and Future Perspectives Toward Prevention	2
Pharmacological Inventions for Alzheimer Treatment in the United States of America: A Revision Patent from 2010 – 2020	2
Environmental Enrichment in Murine Models and Its Translation to Human Factors Improving Conditions in Alzheimer Disease	2

Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-Month Intervention St	2
POSTERS - 15th Conference Clinical Trials Alzheimer’s Disease, November 29- December 2, 2022, San Francisco, CA, USA	2
SYMPOSIA 14th Conference Clinical Trials Alzheimer’s Disease, November 9-12, 2021, Boston, USA	2
SYMPOSIA - 15th Conference Clinical Trials Alzheimer’s Disease, November 29- December 2, 2022, San Francisco, CA, USA	2
Low Amino Acid Score of Breakfast is Associated with the Incidence of Cognitive Impairment in Older Japanese Adults: A Community-Based Longitudinal Study	2
Clusters of Dementia Literacy: Implications from a Survey of Older Adults	2
New Hope for Alzheimer’s Disease	2
Are Population-Level Approaches to Dementia Risk Reduction Under-Researched? A Rapid Review of the Dementia Prevention Literature	2
Adult Renal Dysfunction and Risk of Dementia or Cognitive Decline: Brain-Kidney Axis Hypothesis Based on a Systematic Review and Meta-Analysis	2
Prediction of Cognitive Decline for Enrichment of Alzheimer’s Disease Clinical Trials	2
Study Protocol of a Comprehensive Activity Promotion	2
Burden of Illness in People with Alzheimer’s Disease: A Systematic Review of Epidemiology, Comorbidities and Mortality	2
Lecanemab Clarity AD: Quality-of-Life Results from a Randomized, Double-Blind Phase 3 Trial in Early Alzheimer’s Disease	2
In Vivo Detection of Changes Related to Cortical Columnar Organization and Neuroinflammation Across the AD Continuum	2
Diagnostic Biomarkers of Amyloid and Tau Pathology in Alzheimer’s Disease: An Overview of Tests for Clinical Practice in the United States and Europe	2
Change on Clinical Trial Outcome Assessments: The Search for Meaningfulness	2
Associations of Stages of Objective Memory Impairment with Cerebrospinal Fluid and Neuroimaging Biomarkers of Alzheimer’s Disease	2
Tau Pathologies Mediate the Associations of Vascular Risk Burden with Cognitive Impairments in Non-demented Elders: The CABLE Study	2
Detection Rates of Mild Cognitive Impairment in Primary Care for the United States Medicare Population	2
Evaluation of the Feasibility, Safety and Efficacy of the Use of Intravenous Infusions of Adenosine Triphosphate (ATP) in People Affected by Moderate to Severe Alzheimer's Disease: A Double-Blind Mask	1
Associations between Participant Characteristics and Participant Feedback about an Unsupervised Online Cognitive Assessment in a Research Registry	1
Nutrition-Based Approaches in Clinical Trials Targeting Cognitive Function: Highlights of the CTAD 2020	1
Oral Health as a Risk Factor for Alzheimer Disease	1
Letter to the Editor: Alzheimer’s Disease-Associated APOE ε4 Frequencies in Indian Population Genomes May Suggest Implications in Lecanemab Treatment	1
Cognitive Performance and Incident Alzheimer’s Dementia in Men Versus Women	1
The Effects of Subjective Cognitive Decline on APOE Genotype Disclosure in the Butler Hospital Alzheimer’s Prevention Registry	1
Neuropsychiatric Symptoms in AD: Clinical Trials Targeting Mild Behavioral Impairment: A Report from the International CTAD Task Force	1
A Hierarchical Bayesian Latent Class Model for the Diagnostic Performance of Mini-Mental State Examination and Montreal Cognitive Assessment in Screening Mild Cognitive Impairment Due to Alzheimer’s D	1
Alzheimer’s Disease Research in Japan: A Short History, Current Status and Future Perspectives toward Prevention	1
A Fay-Herriot Model for Estimating Subjective Cognitive Decline among Military Veterans	1
Alzheimer's Disease Prevention Health Coaching	1
Screening over Speech in Unselected Populations for Clinical Trials in AD (PROSPECT-AD): Study Design and Protocol	1
Medical Journey of Patients with Mild Cognitive Impairment and Mild Alzheimer’s Disease Dementia: A Cross-sectional Survey of Patients, Care Partners, and Neurologists	1
A Novel Computerized Cognitive Stress Test to Detect Mild Cognitive Impairment	1
Investigating Partially Discordant Results in Phase 3 Studies of Aducanumab	1
Association of Loneliness with Cognitive Functions	1
Obesity and Brain Health: The Impact of Metabolic Syndrome and Cardiorespiratory Fitness on Cognitive Performances in Middle-Aged Obese Women	1
Initial Experiences with Amyloid-Related Imaging Abnormalities in Patients Receiving Aducanumab Following Accelerated Approval	1
Therapeutic Targets for Alzheimer’s Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report	1
Phase 1/2a Intravenous and Subcutaneous Oligomer-Specific Antibody KHK6640 in Mild to Moderate Alzheimer’s Disease	1
Evaluation of the Fiscal Costs and Consequences of Alzheimer’s Disease in Germany: Microsimulation of Patients’ and Caregivers’ Pathways	1
Editorial: Usefulness of Anchor Based Methods for Determining Clinically Meaningful Change in MCI due to AD	1
How Will Aducanumab Approval Impact AD Research?	1
Subjective Cognitive Complaints: Comparing the Relation between Self-Reported Versus Informant-Reported Subjective Cognitive Complaints and Cognitive Performances in Cognitively Unimpaired, Mild Cogni	1
Alzheimer’s Disease and Aging Association: Identification and Validation of Related Genes	1
The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER): Study Design and Protocol	1
Fructose Consumption is Associated with a Higher Risk of Dementia and Alzheimer’s Disease: A Prospective Cohort Study	1
A Cholecystokinin Analogue Ameliorates Cognitive Deficits and Regulates Mitochondrial Dynamics via the AMPK/Drp1 Pathway in APP/PS1 Mice	1
Pushing through the Barriers: Peer Advice to Increase Physical Activity and Reduce Dementia Risk from Participants in a Massive Open Online Alzheimer’s Focused Course	1
Elecsys Cerebrospinal Fluid Assays Accurately Distinguish Alzheimer’s Disease from Frontotemporal Lobar Degeneration	1
Clinical Implementation of Lecanemab: Challenges, Questions and Solutions	1
Association between Dietary Theobromine and Cognitive Function in a Representative American Population: A Cross-Sectional Study	1
Comparative Efficacy, Safety, Tolerability, and Effectiveness of Antipsychotics in The Treatment of Dementia-Related Psychosis (DRP): A Systematic Literature Review	1
Editorial: Appropriate Use Recommendations for Lecanemab	1
Modulation of Mitochondrial Function as a Therapeutic Strategy for Neurodegenerative Diseases	1
A Japanese Multicenter Study on PET and Other Biomarkers for Subjects with Potential Preclinical and Prodromal Alzheimer’s Disease	1
Chinese Preclinical Alzheimer’s Disease Study (C-PAS): Design and Challenge from PET Acceptance	1
The Dawn of a New Era of Alzheimer’s Research and Drug Development	1
Evaluation of Memantine in AAV-AD Rat: A Model of Late-Onset Alzheimer’s Disease Predementia	1
Associations of Cardiovascular and Non-Cardiovascular Comorbidities with Dementia Risk in Patients with Diabetes: Results from a Large UK Cohort Study	1
A UK-Wide Study Employing Natural Language Processing to Determine What Matters to People about Brain Health to Improve Drug Development: The Electronic Person-Specific Outcome Measure (ePSOM) Program	1
Utility of Environmental Complexity as a Predictor of Alzheimer’s Disease Diagnosis: A Big-Data Machine Learning Approach	1
Embryo Selection for a Carrier of an Early-Onset Alzheimer’s Disease-Associated Mutation in the PSEN1 Gene	1
Association of Preeclampsia with Incident Dementia and Alzheimer’s Disease among Women in the Framingham Offspring Study	1
Implications of Emerging Uses of Genetic Testing for Alzheimer’s Disease	1
Subjective Cognitive Decline in a Registry Sample: Relation to Psychiatric History, Loneliness, and Personality	1
Editorial: Accelerating Innovations for Enhanced Brain Health. Can Artificial Intelligence Advance New Pathways for Drug Discovery for Alzheimer’s and other Neurodegenerative Disorders?	1
A Genetic Validation of the Neurodegeneration Biomarkers Tau-A and Tau-C - A Mendelian Randomization Study	1
Predicting Progression from Normal to MCI and from MCI to AD Using Clinical Variables in the National Alzheimer’s Coordinating Center Uniform Data Set Version 3: Application of Machine Learning Model	1
How Modifiable Are Modifiable Dementia Risk Factors? A Framework for Considering the Modifiability of Dementia Risk Factors	1
Data-Driven Thresholding Statistically Biases ATN Profiling across Cohort Datasets	1
Projected Savings to Canadian Provincial Budgets from Reduced Long-Term Care Home Utilization Due to a Disease-Modifying Alzheimer’s Treatment	1
A Conformational Variant of p53 (U-p53AZ) as Blood-Based Biomarker for the Prediction of the Onset of Symptomatic Alzheimer’s Disease	1
Neuroinflammation Biomarkers in the AT(N) Framework Across the Alzheimer’s Disease Continuum	1
Risk Estimates of Dementia and Alzheimer’s Disease among Different Whole Grain Food Consumption Categories: A Pilot Study	1
Anxiety and Depressive Symptoms and Cortical Amyloid-β Burden in Cognitively Unimpaired Older Adults	1
Female Reproductive Factors and Risk of Mild Cognitive Impairment and Dementia: The HUNT Study	1
US Adults’ Likelihood to Participate in Dementia Prevention Drug Trials: Results from the National Poll on Healthy Aging	1
The Association between Sugar-Sweetened Beverages and Cognitive Function in Middle-Aged and Older People: A Meta-Analysis	1
Editorial: Lecanemab: Appropriate Use Recommendations – A Commentary from a European Perspective	1

Neuroprotective Effects of IVIG against Alzheimer’ s Disease via Regulation of Antigen Processing and Presentation by MHC Class I Molecules in 3xTg-AD Mice	1
A Polymorphism Cluster at the 2q12 locus May Predict Response to Piromelatine in Patients with Mild Alzheimer's Disease	1
Safety, Tolerability and Pharmacokinetics of Icapamespib, a Selective Epichaperome Inhibitor, in Healthy Adults	1
The Critical Role of Biomarkers for Drug Development Targeting the Biology of Aging	1
Mesenchymal Stem Cells Modulate SIRT1/MiR-134/ GSK3β Signaling Pathway in a Rat Model of Alzheimer's Disease	1
China Alzheimer’s Disease and Neurodegenerative Disorder Research (CANDOR) -A Prospective Cohort Study for Alzheimer’s Disease and Vascular Cognitive Impairment	1
Validation of the CogDrisk Instrument as Predictive of Dementia in Four General Community-Dwelling Populations	1
Alzheimer’s Disease Clinical Trial Research Adaptation Following COVID-19 Pandemic Onset: National Sample of Alzheimer’s Clinical Trial Consortium Sites	1
Clinical Correlates of the PET-based Braak Staging Framework in Alzheimer’s Disease	1
Unsupervised Performance of the CogState Brief Battery in the Brain Health Registry: Implications for Detecting Cognitive Decline	1
Association between 9p21-23 Locus and Frailty in a Community-Dwelling Greek Population: Results from the Hellenic Longitudinal Investigation of Ageing and Diet	1
Longitudinal Cognitive Decline in Patients With Mild Cognitive Impairment or Dementia Due to Alzheimer’s Disease	1
Determinants of Post-Operative Cognitive Decline in Elderly People	1
Decreased Gray–White Matter Contrast of [11C]-PiB Uptake in Cognitively Unimpaired Subjects with Severe Obstructive Sleep Apnea	1
Combined Evidence for a Long-Term, Clinical Slowing Effect of Multinutrient Intervention in Prodromal Alzheimer’s Disease: Post-Hoc Analysis of 3-Year Data from the LipiDiDiet Trial	1
Prevention of Alzheimer’s Disease and Cognitive Decline with Diet & Lifestyle: Proceedings of the A. G. Leventis Foundation Conference	1
Clinicians’ Perspectives on How Disease Modifying Drugs for Alzheimer’s Disease Impact Specialty Care	1
Validation, Deployment, and Real-World Implementation of a Modular Toolbox for Alzheimer’s Disease Detection and Dementia Risk Reduction: The AD-RIDDLE Project	1
The Ups and Downs of Amyloid in Alzheimer’s	1
Dual Task Performance Is Associated with Amyloidosis in Cognitively Healthy Adults	1