OOIR: Observatory of International Research

Papers

(The TQCC of Bioimpacts is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	38
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	23
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells	21
Molecular dynamics simulation in tissue engineering	21
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	21
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	18
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	17
Hollow pollen grains as scaffolding building blocks in bone tissue engineering	15
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	14
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	13
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	12
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	10
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	10
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	10
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	9
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	9
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	9
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	8
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	8
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	8
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	8
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	7
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	7

Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7
Regulation of cell fate by cell imprinting approach in vitro	7
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	7
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	6
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	6
Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells	6
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	5
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	5
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	5
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	5
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	5
High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy	5
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	4
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	4
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer	4
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	4
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	4
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	4
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands	4
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	4
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	4
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	4
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	4
Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds	4
To detect potential pathways and target genes in infantile Pompe patients using computational analysis	4
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	4
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	3
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	3
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	3
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	3
CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	3
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment	3
A subspace learning aided matrix factorization for drug repurposing	3
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	3
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	3
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	3
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	3
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	3
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	3
Chitosan nanoparticle-mediated effect of antimiRNA-324-5p on decreasing the ovarian cancer cell proliferation by regulation of GLI1 expression	3
Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers	3
Exosomes in neuron-glia communication: A review on neurodegeneration	3
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	3
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	3
Synthesis and characterization of actively HER-2 Targeted Fe₃O₄@Au nanoparticles for molecular radiosensitization of breast cancer	3

Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	3
University rankings: Time to reconsider	3