OOIR: Observatory of International Research

Papers

(The TQCC of Bioimpacts is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	38
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	23
Molecular dynamics simulation in tissue engineering	22
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	21
The role of artificial intelligence in enhancing breast cancer screening and diagnosis: A review of current advances	21
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells	20
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	18
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	14
Hollow pollen grains as scaffolding building blocks in bone tissue engineering	13
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	12
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	12
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	12
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	10
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	10
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	10
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	9
Autophagy stimulation influenced the angiogenesis and metastasis behavior of human triple-negative breast cancer cells	9
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	9
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	9
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	8
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	8
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	8
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7

Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	7
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7
Regulation of cell fate by cell imprinting approach in vitro	7
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	7
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	6
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	6
Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells	6
High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy	6
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	6
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	6
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	5
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	5
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	5
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	5
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	5
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	5
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	5
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	5
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	4
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	4
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	4
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	4
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	4
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands	4
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer	4
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	4
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	4
To detect potential pathways and target genes in infantile Pompe patients using computational analysis	4
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	4
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	4
Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds	4
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	3
Exosomes in neuron-glia communication: A review on neurodegeneration	3
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	3
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	3
University rankings: Time to reconsider	3
CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	3
Resolvin D1 alleviates lipopolysaccharide-induced in vitro corneal inflammation by modulating macrophage polarization through upregulation of c-Fos expre	3
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	3
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	3
A subspace learning aided matrix factorization for drug repurposing	3
Synthesis and characterization of actively HER-2 Targeted Fe₃O₄@Au nanoparticles for molecular radiosensitization of breast cancer	3
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	3
Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers	3
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	3
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	3

Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	3
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	3