OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	41
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	30
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	30
The role of artificial intelligence in enhancing breast cancer screening and diagnosis: A review of current advances	28
Molecular dynamics simulation in tissue engineering	22
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	17
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	16
Exosomes: Redefining intercellular communication and the future of translational medicine	16
Cell-imprinted substrates as biomimetic platforms for osteoarthritis modeling with mesenchymal stem cells	16
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	15
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	14
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	13
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	13
Autophagy stimulation influenced the angiogenesis and metastasis behavior of human triple-negative breast cancer cells	12
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	11
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	11
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	10
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	10
Spirulina: A promising opportunity to overcome neuropathic pain challenges in chronic kidney disease patients	10
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	9
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	9
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	9
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	9
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	9
Regulation of cell fate by cell imprinting approach in vitro	8

Enantioselective analysis of metoprolol in plasma of hypertensive patients undergoing long-term therapy: Insights for personalized medicine	8
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	8
Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	8
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	7
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	7
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	7
Nanostructured implants for enhanced integration and localized therapy	7
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	7
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	7
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	6
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	6
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	6
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	6
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	6
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	6
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	6
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	6
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	5
Immune-modulatory biomimetic nanoparticles: Advances in design, mechanisms, and nanomedicine applications	5
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	5
Development of a terbium-based coordination polymer nanoprobe for determination of clonazepam in exhaled breath condensate	5
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	5
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	5
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	5
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	5
Exosomes in neuron-glia communication: A review on neurodegeneration	5
Resolvin D1 alleviates lipopolysaccharide-induced in vitro corneal inflammation by modulating macrophage polarization through upregulation of c-Fos expre	5
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	5
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	5
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	5
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	5
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	5
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	4
Ambivalent roles of miRNAs in cancer development via modulating tumor-associated innate immune cells	4
Hierarchical classification of anterior cruciate ligament using deep learning for athletes healthcare	4
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	4
A subspace learning aided matrix factorization for drug repurposing	4
Checkpoint inhibition and beyond: Precision immune engineering for the immune-privileged landscape of ocular malignancies	4
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment	4
Predicting drug protein interactions based on improved support vector data description in unbalanced data	4
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	4
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	4
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	4
University rankings: Time to reconsider	4
DNA methylation as a potential mediator between environmental pollutants and osteoporosis; a current hypothesis	4
Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration	4

Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	4
CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	4
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	4
A new method for early diagnosis and treatment of meniscus injury of knee joint in student physical fitness tests based on deep learning method	3
In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies	3
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	3
Artificial intelligence–guided nanoparticle design for advanced targeted drug delivery	3
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	3
The implications of pharmacogenomics in oncology	3
Exosomes-derived mesenchymal stem cells in corneal regeneration: Properties and challenges	3
Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends	3
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A	3
An efficient hybrid filter-wrapper method based on improved Harris Hawks optimization for feature selection	3
Computational analysis on design and optimization of low-frequency dielectrophoretic microfluidic lab on a chip for Staphylococcus aureus isolation from	3
Bibliometric study of BioImpacts using a technological impact approach	3
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	3
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	3
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	3
Long non-coding RNA PURPL in cancer and cellular regulation: Mechanistic insights and therapeutic potential	3
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	3
The promising applications of 3D printing technology for diagnosis and therapy of cancer: Recent advances and challenges	3
Exaggerating the risks of vaccination is a dangerous health threat	3
Performance of protein N linear epitopes in serodiagnosis of COVID-19 infection	3
The role of bioinformatics algorithms in modern biopharmaceutical design: Progress, challenges, and future perspectives	3
Effect of parenteral L-carnitine in hospitalized patients with moderate to severe COVID-19: A randomized double-blind clinical trial	3
Allogeneic Treg-derived artificial vesicles: A promising therapeutic modality for multiple sclerosis	3
Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K⁺ ion for enhanced efficiency in guanine-rich DNA nanomotor	3
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	3
Promising leads against lung cancer from the plants in Lamiaceae family	3
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections	3
IgY-mediated protection against Vibrio cholerae infection: Efficacy of avian antibodies targeting a chimeric recombinant protein	3
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	2
Material synthesis and design optimization of biomaterials for biomedical implant applications	2
Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity	2
Anticancer impacts of the unicellular cyanobacterium Chroococcus turgidus bioactive compounds in colorectal adenocarcinoma	2
Recent advances in electrochemical strategies for bacteria detection	2
An update on a technical method of cartilage decellularization: (a physical-based protocol)	2
Hybrid deep learning models for text-based identification of gene-disease associations	2
Safety and efficacy of extracellular vesicles in individuals with cancer; A systematic review	2
Burn wound healing using adipose-derived mesenchymal stem cells and manganese nanoparticles in polycaprolactone/gelatin electrospun nanofibers in rats	2
The emergence of advanced technologies in the pharmacy profession and the need for education: The case of point-of-care sensing systems and 3D printing of pharmaceuticals	2
Targeted delivery of doxorubicin using RSV F-protein modified breast cancer-derived exosomes in breast cancer-bearing mice	2
The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development	2
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	2
Classification of recurrent implantation failure patients using peripheral blood immunological and metabolic markers	2
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis	2
The interplay between non-coding RNAs and Wnt signaling pathway in leukemia: A narrative review	2
Targeted therapy for liver cancer: Current status and future directions	2
Micro-extraction, pre-concentration, and microfluidic-based separation of organophosphate insecticides followed by the miniaturized electrochemical detection system	2
Functionality of immune cells in COVID-19 infection: development of cell-based therapeutics	2
The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials	2
Chondrogenic Potential of PMSCs Cultured on Chondroitin Sulfate/Gelatin -Modified DBM Scaffold	2
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives	2
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	2
Dutasteride-loaded nanostructured lipid carrier for androgenic alopecia treatment – An in vivo study	2
Organoid-engineered neurovascular units for drug discovery and neurodegeneration research	2
Cloth-based microfluidic devices integrated onto the patch as wearable colorimetric sensors for simultaneous sweat analysis	2
Exploring the potential of tubulin-associated unit protein as a biomarker for schizophrenia	2
A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models	2
SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system	2
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model	2
Silibinin exhibits anti-tumor effects in a breast cancer stem cell model by targeting stemness and induction of differentiation and apoptosis	2
Recent innovations in nanomedicine and nano-based techniques for the treatment of breast cancer	2
Celastrol overcomes 5-fluorouracil resistance in osteosarcoma cells through p53-mediated apoptotic pathway modulation and P-glycoprotein inhibition: A comprehensive mechanistic study	2