OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	34
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	33
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells	21
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	20
Molecular dynamics simulation in tissue engineering	20
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	19
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	18
Hollow pollen grains as scaffolding building blocks in bone tissue engineering	15
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	12
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	12
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	12
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	10
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	10
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	10
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	10
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	9
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	9
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	9
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8
Designing robust chitosan-based hydrogels for stem cell nesting under oxidative stress	8
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	8
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	8
Regulation of cell fate by cell imprinting approach in vitro	7
Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7

Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	6
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	6
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	6
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	6
Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	5
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	5
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	5
Fabrication, characterization, and optimization of a novel copper-incorporated chitosan/gelatin-based scaffold for bone tissue engineering applications	5
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	5
High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy	5
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	5
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	4
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	4
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	4
To detect potential pathways and target genes in infantile Pompe patients using computational analysis	4
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	4
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	4
The active lung microbiota landscape of COVID-19 patients through the metatranscriptome data analysis	4
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands	4
Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds	4
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	4
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	4
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	4
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer	4
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	4
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	3
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	3
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	3
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	3
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	3
Exosomes in neuron-glia communication: A review on neurodegeneration	3
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	3
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	3
Synthesis and characterization of actively HER-2 Targeted Fe₃O₄@Au nanoparticles for molecular radiosensitization of breast cancer	3
Expression of functional eGFP-fused antigen-binding fragment of ranibizumab in Pichia pastoris	3
Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers	3
Chitosan nanoparticle-mediated effect of antimiRNA-324-5p on decreasing the ovarian cancer cell proliferation by regulation of GLI1 expression	3
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	3
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	3
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	3
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	3
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A	2
Bibliometric study of BioImpacts using a technological impact approach	2
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	2

Performance of protein N linear epitopes in serodiagnosis of COVID-19 infection	2
On the issue of transparency on the internal investigation of academic bullying	2
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	2
University rankings: Time to reconsider	2
Exosomes as versatile nanoscaled biocompartments in cancer therapy and/or resistance	2
Promising leads against lung cancer from the plants in Lamiaceae family	2
In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies	2
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections	2
Effect of parenteral L-carnitine in hospitalized patients with moderate to severe COVID-19: A randomized double-blind clinical trial	2
Predicting drug protein interactions based on improved support vector data description in unbalanced data	2
IgY-mediated protection against Vibrio cholerae infection: Efficacy of avian antibodies targeting a chimeric recombinant protein	2
Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration	2
The implications of pharmacogenomics in oncology	2
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	2
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	2
Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends	2
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	2
A new method for early diagnosis and treatment of meniscus injury of knee joint in student physical fitness tests based on deep learning method	2
An efficient hybrid filter-wrapper method based on improved Harris Hawks optimization for feature selection	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	2
DNA methylation as a potential mediator between environmental pollutants and osteoporosis; a current hypothesis	2
Enhanced characterization of beta cell mass in a Tg(Pdx1-GFP) mouse model	2
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	2
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis	1
Effect of Honokiol on culture time and survival of Alzheimer’s disease iPSC-derived neurons	1
Anticancer impacts of the unicellular cyanobacterium Chroococcus turgidus bioactive compounds in colorectal adenocarcinoma	1
Micro-extraction, pre-concentration, and microfluidic-based separation of organophosphate insecticides followed by the miniaturized electrochemical detection system	1
Hybrid deep learning models for text-based identification of gene-disease associations	1
Optogenetics: A new tool for cancer investigation and treatment	1
The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials	1
Recent advancements in cell-based models for auditory disorders	1
Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K⁺ ion for enhanced efficiency in guanine-rich DNA nanomotor	1
Therapeutic effects of silver nanoparticle and L-carnitine on aerobic vaginitis in mice: an experimental study	1
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	1
Material synthesis and design optimization of biomaterials for biomedical implant applications	1
SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system	1
Lactiplantibacillus plantarum exerts anticancer effects and increase the chemosensitivity of 5-fluorouracil against oral cancer cells in vitro	1
Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force	1
Abuse potential of fentanyl and fentanyl analogues	1
A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models	1
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach	1
Safety and efficacy of extracellular vesicles in individuals with cancer; A systematic review	1
An update on a technical method of cartilage decellularization: (a physical-based protocol)	1
Chondrogenic Potential of PMSCs Cultured on Chondroitin Sulfate/Gelatin -Modified DBM Scaffold	1
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives	1
Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury	1
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	1
Silibinin exhibits anti-tumor effects in a breast cancer stem cell model by targeting stemness and induction of differentiation and apoptosis	1
Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis	1
Targeting immune checkpoints as a new therapeutic strategy for intra-hepatic cholangiocarcinoma	1
Autophagy induced macrophages by α-alumina(α-AL2O3) conjugated cysteine peptidase, enhances the cytotoxic activity of CD8+ T lymphocytes against Leishmania major	1
Cloth-based microfluidic devices integrated onto the patch as wearable colorimetric sensors for simultaneous sweat analysis	1
Recent advances in electrochemical strategies for bacteria detection	1
An opinion on the impacts of COVID-19 worldwide	1
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model	1
Burn wound healing using adipose-derived mesenchymal stem cells and manganese nanoparticles in polycaprolactone/gelatin electrospun nanofibers in rats	1
The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development	1
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	1
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	1
Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity	1
Functionality of immune cells in COVID-19 infection: development of cell-based therapeutics	1
Drug self-delivery systems: A comprehensive review on small molecule nanodrugs	1