OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
The role of artificial intelligence in enhancing breast cancer screening and diagnosis: A review of current advances	48
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	30
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	27
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	25
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	25
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	17
Molecular dynamics simulation in tissue engineering	16
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	15
Exosomes: Redefining intercellular communication and the future of translational medicine	14
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	13
Cell-imprinted substrates as biomimetic platforms for osteoarthritis modeling with mesenchymal stem cells	13
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	12
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	12
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	11
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	11
Autophagy stimulation influenced the angiogenesis and metastasis behavior of human triple-negative breast cancer cells	11
Spirulina: A promising opportunity to overcome neuropathic pain challenges in chronic kidney disease patients	10
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	9
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	9
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	9
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	9
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	9
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	9
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	8
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8

Regulation of cell fate by cell imprinting approach in vitro	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7
Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	6
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	6
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	6
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	6
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	6
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	6
Enantioselective analysis of metoprolol in plasma of hypertensive patients undergoing long-term therapy: Insights for personalized medicine	6
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	6
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	6
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	5
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	5
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	5
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	5
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	5
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	5
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	5
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	5
Immune-modulatory biomimetic nanoparticles: Advances in design, mechanisms, and nanomedicine applications	5
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	5
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	4
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	4
Exosomes in neuron-glia communication: A review on neurodegeneration	4
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	4
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	4
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	4
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	4
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	4
Resolvin D1 alleviates lipopolysaccharide-induced in vitro corneal inflammation by modulating macrophage polarization through upregulation of c-Fos expre	4
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	4
A subspace learning aided matrix factorization for drug repurposing	4
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment	4
Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	4
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	4
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	4
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	4
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	3
Predicting drug protein interactions based on improved support vector data description in unbalanced data	3
Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration	3
A new method for early diagnosis and treatment of meniscus injury of knee joint in student physical fitness tests based on deep learning method	3
Ambivalent roles of miRNAs in cancer development via modulating tumor-associated innate immune cells	3

CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	3
University rankings: Time to reconsider	3
An efficient hybrid filter-wrapper method based on improved Harris Hawks optimization for feature selection	3
The role of bioinformatics algorithms in modern biopharmaceutical design: Progress, challenges, and future perspectives	3
Effect of parenteral L-carnitine in hospitalized patients with moderate to severe COVID-19: A randomized double-blind clinical trial	3
Hierarchical classification of anterior cruciate ligament using deep learning for athletes healthcare	3
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	3
DNA methylation as a potential mediator between environmental pollutants and osteoporosis; a current hypothesis	3
In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies	3
Performance of protein N linear epitopes in serodiagnosis of COVID-19 infection	3
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A	3
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	2
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives	2
An update on a technical method of cartilage decellularization: (a physical-based protocol)	2
An opinion on the impacts of COVID-19 worldwide	2
The emergence of advanced technologies in the pharmacy profession and the need for education: The case of point-of-care sensing systems and 3D printing of pharmaceuticals	2
Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K⁺ ion for enhanced efficiency in guanine-rich DNA nanomotor	2
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model	2
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	2
The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	2
Exosomes-derived mesenchymal stem cells in corneal regeneration: Properties and challenges	2
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	2
Exaggerating the risks of vaccination is a dangerous health threat	2
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	2
Hybrid deep learning models for text-based identification of gene-disease associations	2
The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials	2
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	2
Recent innovations in nanomedicine and nano-based techniques for the treatment of breast cancer	2
The implications of pharmacogenomics in oncology	2
Functionality of immune cells in COVID-19 infection: development of cell-based therapeutics	2
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	2
Chondrogenic Potential of PMSCs Cultured on Chondroitin Sulfate/Gelatin -Modified DBM Scaffold	2
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	2
Material synthesis and design optimization of biomaterials for biomedical implant applications	2
Promising leads against lung cancer from the plants in Lamiaceae family	2
Allogeneic Treg-derived artificial vesicles: A promising therapeutic modality for multiple sclerosis	2
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections	2
IgY-mediated protection against Vibrio cholerae infection: Efficacy of avian antibodies targeting a chimeric recombinant protein	2
Organoid-engineered neurovascular units for drug discovery and neurodegeneration research	2
Micro-extraction, pre-concentration, and microfluidic-based separation of organophosphate insecticides followed by the miniaturized electrochemical detection system	2
Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity	2
Celastrol overcomes 5-fluorouracil resistance in osteosarcoma cells through p53-mediated apoptotic pathway modulation and P-glycoprotein inhibition: A comprehensive mechanistic study	2
Artificial intelligence–guided nanoparticle design for advanced targeted drug delivery	2
Safety and efficacy of extracellular vesicles in individuals with cancer; A systematic review	2
Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury	2
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach	2
Enhanced characterization of beta cell mass in a Tg(Pdx1-GFP) mouse model	2
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	2
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	2
Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends	2
Bibliometric study of BioImpacts using a technological impact approach	2