OOIR: Observatory of International Research

Papers

(The median citation count of Bioimpacts is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Smart IoT-driven biosensors for EEG-based driving fatigue detection: A CNN-XGBoost model enhancing healthcare quality	38
A cancer diagnosis transformer model based on medical IoT data for clinical measurements in predictive care systems	23
Effect of α-pinene and thymoquinone on the differentiation of bone marrow mesenchymal stem cells into neuroprogenitor cells	21
Molecular dynamics simulation in tissue engineering	21
Photoplethysmography based non-invasive blood glucose estimation using systolic-diastolic framing MFCC features and machine learning regression	21
Inhibitory effect of miR342 on the progression of triple-negative breast cancer cells in vitro and in the mice model	18
Advances in nanomaterials for precision drug delivery: Insights into pharmacokinetics and toxicity	17
Hollow pollen grains as scaffolding building blocks in bone tissue engineering	15
Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells	14
Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems	13
Homozygous mutation in CSF1R causes brain abnormalities, neurodegeneration, and dysosteosclerosis (BANDDOS)	12
Targeting long non-coding RNAs as new modulators in anti-EGFR resistance mechanisms	10
Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy	10
Investigating the function and targeting of MET protein as an oncogene kinase in pancreatic ductal adenocarcinoma: A microarray data integration	10
The treatment of psoriasis via herbal formulation and nano-polyherbal formulation: A new approach	9
MicroRNA-372-3p impairs fatty acid metabolism in hepatocellular carcinoma cells by targeting CPT1A and ACSL4	9
Potential role of epidermal growth factor receptors (EGFR) signaling in the pathogenesis and management of hepatocellular carcinoma	9
Enhanced efficacy of breast cancer treatment with etoposide-graphene oxide nanogels: A novel nanomedicine approach	8
Thalidomide augments maturation and T helper 1-inducing capacity of monocyte-derived dendritic cells in vitro	8
Targeting hypoxia-inducible factor 1 alpha augments synergistic effects of chemo/immunotherapy via modulating tumor microenvironment in a breast cancer mouse model	8
Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells	8
Anti-Alzheimer effects of the newly synthesized cationic compounds as multi-target dual hAChE/hBuChE inhibitor: An in silico, in vitro, and in vivo approach	8
The effects of Fe₂O₃ nanoparticles on catalytic function of human acetylcholinesterase: size and concentration role	7
Biosynthesis of sulfur quantum dots and cerium oxide nanoparticles for bioimaging and reactive oxygen species modulation in Y79 retinoblastoma cancer cells	7
Differentiation of human endometrial stem cells encapsulated in alginate hydrogel into oocyte-like cells	7

Biologically inspired laccase-mimicking OVA-Cu complex for degradation of organic dye pollutant: Artificial neural network modeling and optimization	7
Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model	7
Regulation of cell fate by cell imprinting approach in vitro	7
Unveiling the biological effects of radio-frequency and extremely-low frequency electromagnetic fields on the central nervous system performance	7
Correction: Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers	7
COVID-19: An overview on possible transmission ways, sampling matrices and diagnosis	6
Deciphering the role of classical oestrogen receptor in insulin resistance and type 2 diabetes mellitus: From molecular mechanism to clinical evidence	6
Synthesis and functionalization of mucoadhesive mesoporous silica particles containing diphenhydramine for treatment of aphthous ulcers	6
Systemic nitric oxide metabolites and the chance of pre-diabetes regression to normoglycemia: A 9-year cohort study	6
Differentiation and molecular characterization of endothelial progenitor and vascular smooth muscle cells from induced pluripotent stem cells	6
Mesenchymal stem cells as a therapeutic strategy to combat oxidative stress-mediated neuropathic pain	5
Mode of binding, kinetic and thermodynamic properties of a lipid-like drug (Fingolimod) interacting with Human Serum Albumin	5
The effect of Sertoli cell exosomes on spermatogonia stem cells differentiation	5
Platelet-derived microparticles enhance Ara-C-induced cell death in acute lymphoblastic leukemia (Nalm-6)	5
Combination of mesenchymal stem cell sheet with poly-caprolactone nanofibrous mat and Gelfoam increased osteogenesis capacity in rat calvarial defect	5
High efficacy of tamoxifen-loaded L-lysine coated magnetic iron oxide nanoparticles in cell cycle arrest and anti-cancer activity for breast cancer therapy	5
Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective	4
Preparation and evaluation of a polycaprolactone/chitosan/propolis fibrous nanocomposite scaffold as a tissue engineering skin substitute	4
Recent advances in cancer immunotherapy: Modulation of tumor microenvironment by Toll-like receptor ligands	4
Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model	4
Evaluation of osteogenic differentiation of human mesenchymal stem cells (hMSCs) on random and aligned polycaprolactone-polyaniline-gelatin scaffolds	4
Growth and invasion inhibition of T47D ductal carcinoma cells by the association of docetaxel with a bioactive agent in neutral nanosuspension	4
The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration	4
Repairing rat calvarial defects by adipose mesenchymal stem cells and novel freeze-dried three-dimensional nanofibrous scaffolds	4
To detect potential pathways and target genes in infantile Pompe patients using computational analysis	4
Nanobody-functionalized liposomal doxorubicin: A novel strategy for angiogenesis suppression via VEGFR2 targeting	4
Combination of pioglitazone and dendritic cell to optimize efficacy of immune cell therapy in CT26 tumor models	4
microRNAs shuttled by mesenchymal stromal cell-derived exosomes in coronary artery disease: A systematic review of preclinical studies	4
Evaluation of poly (lactic-co-glycolic acid) nanoparticles to improve the therapeutic efficacy of paclitaxel in breast cancer	4
Advances in nanocarrier-mediated delivery of chrysin: Enhancing solubility, bioavailability, and anticancer efficacy	4
Identification and characterization of antibacterial peptides produced by Lactobacillus plantarum 1407	3
Stimuli-responsive synthesis of silver nanoparticles applying green and chemical reduction approaches	3
CFP10–loaded PLGA nanoparticles as a booster vaccine confer protective immunity against Mycobacterium bovis	3
CAR-T cell therapy as an approach for pediatric hematological malignancies in regenerative therapy: Current status and clinical outcomes	3
Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment	3
A subspace learning aided matrix factorization for drug repurposing	3
Optimized cutaneous delivery of anti-wrinkle dipeptide KT via molecular modification: Preformulation, permeation, and the importance of conjugate chain length	3
Cancer treatment comes to age: from one-size-fits-all to next-generation sequencing (NGS) technologies	3
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres	3
SBFI-26 enhances apoptosis in docetaxel-treated triple-negative breast cancer cells by increasing ROS levels	3
Computational studies and structural insights for discovery of potential natural aromatase modulators for hormone-dependent breast cancer	3
Designing of multi-epitope vaccine against Varicella zoster virus (VZV) using immunoinformatics and structural analysis: In silico study	3
Chitosan nanoparticle-mediated effect of antimiRNA-324-5p on decreasing the ovarian cancer cell proliferation by regulation of GLI1 expression	3
Diagnosis of acute myocardial infarction: highlighting cardiac troponins as vital biomarkers	3
Exosomes in neuron-glia communication: A review on neurodegeneration	3
Effect of microRNA-141-3p, E2F3, CDK3, and KAT2B overexpression on histologic tumor grade and metastasis status in untreated breast cancer tissues	3
Artesunate reduces sepsis-mediated acute lung injury in a SIRT1-dependent manner	3
Synthesis and characterization of actively HER-2 Targeted Fe₃O₄@Au nanoparticles for molecular radiosensitization of breast cancer	3
Synthesis and characterization of a magnetic bacterial cellulose-chitosan nanocomposite and evaluation of its applicability for osteogenesis	3
University rankings: Time to reconsider	3

Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses	3
Bone marrow mesenchymal stem cells improve cognitive impairments induced by methamphetamine in rats and reduce relapse	3
Predicting drug protein interactions based on improved support vector data description in unbalanced data	2
Retinoic acid-releasing scaffold based on chitosan hydrogel and testis decellular plates	2
Static electromagnetic field and recombinant human fibroblasts encoding miR-451 and miR-16 increased cell trans-differentiation to CD⁷¹⁺ and CD^235a+ erythroid like progenitor	2
Comparative molecular docking and toxicity between carbon-capped metal oxide nanoparticles and standard drugs in cancer and bacterial infections	2
Regulation of ubiquitin-proteasome system and its relative pathways in pancreatic adenocarcinoma	2
A new method for early diagnosis and treatment of meniscus injury of knee joint in student physical fitness tests based on deep learning method	2
Allogeneic Treg-derived artificial vesicles: A promising therapeutic modality for multiple sclerosis	2
In-silico based discovery of potential Keap1 inhibitors using the strategies of pharmacophore screening, molecular docking, and MD simulation studies	2
DNA methylation as a potential mediator between environmental pollutants and osteoporosis; a current hypothesis	2
IgY-mediated protection against Vibrio cholerae infection: Efficacy of avian antibodies targeting a chimeric recombinant protein	2
A potential mechanism for tau protein modulating in schizophrenia with transcranial direct current stimulation intervention: A randomized controlled trial	2
Enhanced characterization of beta cell mass in a Tg(Pdx1-GFP) mouse model	2
New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A	2
Bibliometric study of BioImpacts using a technological impact approach	2
Performance of protein N linear epitopes in serodiagnosis of COVID-19 infection	2
The implications of pharmacogenomics in oncology	2
An efficient hybrid filter-wrapper method based on improved Harris Hawks optimization for feature selection	2
Oil-in-water nanoemulsions for glaucoma treatment: An insight into the latest trends	2
Promising leads against lung cancer from the plants in Lamiaceae family	2
Unlocking the potential of lumateperone and novel anti-psychotics for schizophrenia	2
Comparison the therapeutic effects of bone marrow CD144⁺ endothelial cells and CD146⁺ mesenchymal stem cells in POF rats	2
Effect of parenteral L-carnitine in hospitalized patients with moderate to severe COVID-19: A randomized double-blind clinical trial	2
Exosomes as versatile nanoscaled biocompartments in cancer therapy and/or resistance	2
Ambivalent roles of miRNAs in cancer development via modulating tumor-associated innate immune cells	2
Simultaneous suppression of miR-21 and restoration of miR-145 in gastric cancer cells; a promising strategy for inhibition of cell proliferation and migration	2
Abuse potential of fentanyl and fentanyl analogues	1
A human acellular dermal matrix coated with zinc oxide nanoparticles accelerates tendon repair in patients with hand flexor tendon injuries in zone 5 of the hand	1
Protective effects of sumatriptan against optic nerve injury in rats via modulation of kynurenine pathway, oxidative stress and apoptosis	1
Recent innovations in nanomedicine and nano-based techniques for the treatment of breast cancer	1
Multi spectroscopic and molecular simulation studies of propyl acridone binding to calf thymus DNA in the presence of electromagnetic force	1
Hybrid deep learning models for text-based identification of gene-disease associations	1
Autophagy induced macrophages by α-alumina(α-AL2O3) conjugated cysteine peptidase, enhances the cytotoxic activity of CD8+ T lymphocytes against Leishmania major	1
Chemo-immune cell therapy by intratumoral injection of adoptive NK cells with capecitabine in gastric cancer xenograft model	1
Recent advancements in cell-based models for auditory disorders	1
Stabilization of Hoogsteen H-bonds in G-quartet sheets by coordinated K⁺ ion for enhanced efficiency in guanine-rich DNA nanomotor	1
Recent advances in electrochemical strategies for bacteria detection	1
Molecular properties prediction, anticancer and anti-inflammatory activities of some pyrimido[1,2-b]pyridazin-2-one derivatives	1
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer	1
Burn wound healing using adipose-derived mesenchymal stem cells and manganese nanoparticles in polycaprolactone/gelatin electrospun nanofibers in rats	1
Functionality of immune cells in COVID-19 infection: development of cell-based therapeutics	1
Evaluating the presence of deregulated tumoral onco-microRNAs in serum-derived exosomes of gastric cancer patients as noninvasive diagnostic biomarkers	1
The promise of gene therapy in common types of dementia	1
Drug self-delivery systems: A comprehensive review on small molecule nanodrugs	1
The effectiveness of antioxidant agents in delaying progression of diabetic nephropathy: A systematic review of randomized controlled trials	1
Synthesis, characterization, and evaluation of pH-sensitive doxorubicin-loaded functionalized graphene oxide in osteosarcoma cells	1
Micro-extraction, pre-concentration, and microfluidic-based separation of organophosphate insecticides followed by the miniaturized electrochemical detection system	1
Effect of Honokiol on culture time and survival of Alzheimer’s disease iPSC-derived neurons	1
An opinion on the impacts of COVID-19 worldwide	1
Anticancer impacts of the unicellular cyanobacterium Chroococcus turgidus bioactive compounds in colorectal adenocarcinoma	1
Uncovering the anticancer effects of Bhallataka Taila in lung cancer: A metabolomic and network pharmacology approach	1
A promising breakthrough in pancreatic cancer research: The potential of spheroids as 3D models	1
Poly (acrylic acid)/tricalcium phosphate nanoparticles scaffold enriched with exosomes for cell-free therapy in bone tissue engineering: An in vivo evaluation	1
Reduced inflammation following human endometrial stromal/stem cell injection into male Wistar rats with cisplatin-induced acute kidney injury	1
The role of tumor microenvironment and self-organization in cancer progression: Key insights for therapeutic development	1
Silibinin exhibits anti-tumor effects in a breast cancer stem cell model by targeting stemness and induction of differentiation and apoptosis	1
Assessment of the biocompatibility and biodistribution of fluorescent oleic acid capped ZnSe/CdS/ core shell quantum dots after intravenous injection in Balb/c mice	1
Design and computational analysis of an effective multi-epitope vaccine candidate using subunit B of cholera toxin as a build-in adjuvant against urinary tract infections	1
Safety and efficacy of extracellular vesicles in individuals with cancer; A systematic review	1
Lactiplantibacillus plantarum exerts anticancer effects and increase the chemosensitivity of 5-fluorouracil against oral cancer cells in vitro	1
Optogenetics: A new tool for cancer investigation and treatment	1
Targeting immune checkpoints as a new therapeutic strategy for intra-hepatic cholangiocarcinoma	1
SARS-CoV-2 vaccine-triggered autoimmunity: Molecular mimicry and/or bystander activation of the immune system	1
Cloth-based microfluidic devices integrated onto the patch as wearable colorimetric sensors for simultaneous sweat analysis	1
Chondrogenic Potential of PMSCs Cultured on Chondroitin Sulfate/Gelatin -Modified DBM Scaffold	1
An update on a technical method of cartilage decellularization: (a physical-based protocol)	1
Material synthesis and design optimization of biomaterials for biomedical implant applications	1
STAT signaling pathways in immune cells and their associated mechanisms in cancer pathogenesis	1
Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity	1
Fabrication of mesoporous silica nanoparticles for targeted delivery of sunitinib to ovarian cancer cells	1
Kopexil vs minoxidil: In vivo comparative study on hair growth, hair growth promoting factors and toxicity	1