OOIR: Observatory of International Research

Papers

(The H4-Index of Biomedicines is 59. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Inflammatory Mechanisms Contributing to Endothelial Dysfunction	242
Advances in Nanomaterial-Mediated Photothermal Cancer Therapies: Toward Clinical Applications	234
Modern Wound Dressings: Hydrogel Dressings	179
Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics	165
Current FDA-Approved Therapies for High-Grade Malignant Gliomas	161
Neuroinflammation in Alzheimer’s Disease	141
Long-Term Impact of COVID-19: A Systematic Review of the Literature and Meta-Analysis	140
Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches	120
Long COVID-19 Syndrome: A Comprehensive Review of Its Effect on Various Organ Systems and Recommendation on Rehabilitation Plans	117
Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases	117
Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance	116
Natural Photosensitizers in Antimicrobial Photodynamic Therapy	116
Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma	116
Roles of XBP1s in Transcriptional Regulation of Target Genes	107
Meningioma: A Review of Epidemiology, Pathology, Diagnosis, Treatment, and Future Directions	107
Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling	100
Dopamine in Health and Disease: Much More Than a Neurotransmitter	99
The Role of Curcumin in Cancer Treatment	98
Naringin and Naringenin: Their Mechanisms of Action and the Potential Anticancer Activities	97
The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery	97
Emerging SARS-CoV-2 Variants of Concern (VOCs): An Impending Global Crisis	95
Polycrystalline Diamond as a Potential Material for the Hard-on-Hard Bearing of Total Hip Prosthesis: Von Mises Stress Analysis	93
Intestinal Barrier and Permeability in Health, Obesity and NAFLD	90
A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives	85
Targeting Drug Chemo-Resistance in Cancer Using Natural Products	85

Pathophysiology of Cardiovascular Diseases: New Insights into Molecular Mechanisms of Atherosclerosis, Arterial Hypertension, and Coronary Artery Disease	83
A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold	83
Neurogenic Inflammation: The Participant in Migraine and Recent Advancements in Translational Research	82
Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases	80
Advances and Limitations of Antibody Drug Conjugates for Cancer	78
Effects of Antibiotics upon the Gut Microbiome: A Review of the Literature	78
The Role of Adipokines in Health and Disease	77
Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future?	76
Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer	76
Can Metformin Exert as an Active Drug on Endothelial Dysfunction in Diabetic Subjects?	74
The Effect of Tortuosity on Permeability of Porous Scaffold	74
Vitamin D and Its Role in the Lipid Metabolism and the Development of Atherosclerosis	72
Nanotechnology as a Promising Approach to Combat Multidrug Resistant Bacteria: A Comprehensive Review and Future Perspectives	72
Hyaluronic Acid Hydrogels Crosslinked in Physiological Conditions: Synthesis and Biomedical Applications	71
The Structure, Activation and Signaling of IRE1 and Its Role in Determining Cell Fate	71
Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study	68
Inflammatory Mediators and Pain in Endometriosis: A Systematic Review	68
Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?	67
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits	67
Oxidative Stress in Ischemia/Reperfusion Injuries following Acute Ischemic Stroke	66
Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway	65
Application of CAR-T Cell Therapy beyond Oncology: Autoimmune Diseases and Viral Infections	65
Battle Royale: Innate Recognition of Poxviruses and Viral Immune Evasion	65
Functional Enrichment Analysis of Regulatory Elements	63
Less Can Be More: The Hormesis Theory of Stress Adaptation in the Global Biosphere and Its Implications	63
Crosstalk between Gut Microbiota and Host Immunity: Impact on Inflammation and Immunotherapy	62
Current Limitations and Recent Progress in Nanomedicine for Clinically Available Photodynamic Therapy	62
Exosomes: Potential Disease Biomarkers and New Therapeutic Targets	62
The Selenoprotein Glutathione Peroxidase 4: From Molecular Mechanisms to Novel Therapeutic Opportunities	62
Flavonoids: Potential Candidates for the Treatment of Neurodegenerative Disorders	62
Oxidative Stress, Mitochondrial Dysfunction, and Neuroprotection of Polyphenols with Respect to Resveratrol in Parkinson’s Disease	62
Cisplatin Mouse Models: Treatment, Toxicity and Translatability	61
Non-Immunotherapy Application of LNP-mRNA: Maximizing Efficacy and Safety	60
Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs	60
Smart and Biomimetic 3D and 4D Printed Composite Hydrogels: Opportunities for Different Biomedical Applications	59
Post-Operative Adhesions: A Comprehensive Review of Mechanisms	59
Biomarkers and Utility of the Antioxidant Potential of Probiotic Lactobacilli and Bifidobacteria as Representatives of the Human Gut Microbiota	59