OOIR: Observatory of International Research

Papers

(The H4-Index of Biomedicines is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-08-01 to 2024-08-01.)

Article	Citations
Inflammatory Mechanisms Contributing to Endothelial Dysfunction	225
Advances in Nanomaterial-Mediated Photothermal Cancer Therapies: Toward Clinical Applications	214
Modern Wound Dressings: Hydrogel Dressings	162
Current FDA-Approved Therapies for High-Grade Malignant Gliomas	153
The Anti-Inflammatory and Antioxidant Properties of n-3 PUFAs: Their Role in Cardiovascular Protection	150
Bioavailability Enhancement Techniques for Poorly Aqueous Soluble Drugs and Therapeutics	142
Arginine and Endothelial Function	139
Long-Term Impact of COVID-19: A Systematic Review of the Literature and Meta-Analysis	136
Neuroinflammation in Alzheimer’s Disease	134
Long COVID-19 Syndrome: A Comprehensive Review of Its Effect on Various Organ Systems and Recommendation on Rehabilitation Plans	113
Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance	110
Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma	108
Cutaneous Squamous Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches	106
Implication of Intestinal Barrier Dysfunction in Gut Dysbiosis and Diseases	106
Revisiting Traumatic Brain Injury: From Molecular Mechanisms to Therapeutic Interventions	106
Natural Photosensitizers in Antimicrobial Photodynamic Therapy	103
Meningioma: A Review of Epidemiology, Pathology, Diagnosis, Treatment, and Future Directions	102
Roles of XBP1s in Transcriptional Regulation of Target Genes	101
miR-98 Regulates TMPRSS2 Expression in Human Endothelial Cells: Key Implications for COVID-19	99
Tackling Antibiotic Resistance with Compounds of Natural Origin: A Comprehensive Review	98
Emerging SARS-CoV-2 Variants of Concern (VOCs): An Impending Global Crisis	95
Role of Microbiota-Gut-Brain Axis in Regulating Dopaminergic Signaling	95
Dopamine in Health and Disease: Much More Than a Neurotransmitter	94
Polycrystalline Diamond as a Potential Material for the Hard-on-Hard Bearing of Total Hip Prosthesis: Von Mises Stress Analysis	90
The Challenges and Strategies of Antisense Oligonucleotide Drug Delivery	90

The Role of Curcumin in Cancer Treatment	86
Naringin and Naringenin: Their Mechanisms of Action and the Potential Anticancer Activities	86
Intestinal Barrier and Permeability in Health, Obesity and NAFLD	85
Radioprotection and Radiomitigation: From the Bench to Clinical Practice	82
Neurogenic Inflammation: The Participant in Migraine and Recent Advancements in Translational Research	79
Mitochondrial Oxidative Stress and “Mito-Inflammation”: Actors in the Diseases	77
Natural Products, Alone or in Combination with FDA-Approved Drugs, to Treat COVID-19 and Lung Cancer	76
Advances and Limitations of Antibody Drug Conjugates for Cancer	75
Effects of Antibiotics upon the Gut Microbiome: A Review of the Literature	75
The Effect of Tortuosity on Permeability of Porous Scaffold	72
A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives	72
Can Metformin Exert as an Active Drug on Endothelial Dysfunction in Diabetic Subjects?	72
Mitochondrial Dysfunction in Alzheimer’s Disease: A Biomarker of the Future?	71
Targeting Drug Chemo-Resistance in Cancer Using Natural Products	70
The Structure, Activation and Signaling of IRE1 and Its Role in Determining Cell Fate	70
Pathophysiology of Cardiovascular Diseases: New Insights into Molecular Mechanisms of Atherosclerosis, Arterial Hypertension, and Coronary Artery Disease	70
A Comprehensive Review on Collagen Type I Development of Biomaterials for Tissue Engineering: From Biosynthesis to Bioscaffold	68
Persistent Endothelial Dysfunction in Post-Acute COVID-19 Syndrome: A Case-Control Study	68
Vitamin D and Its Role in the Lipid Metabolism and the Development of Atherosclerosis	68
Nanotechnology as a Promising Approach to Combat Multidrug Resistant Bacteria: A Comprehensive Review and Future Perspectives	67
Inflammatory Mediators and Pain in Endometriosis: A Systematic Review	66
Hyaluronic Acid Hydrogels Crosslinked in Physiological Conditions: Synthesis and Biomedical Applications	64
Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?	64
Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway	63
Application of CAR-T Cell Therapy beyond Oncology: Autoimmune Diseases and Viral Infections	63
Less Can Be More: The Hormesis Theory of Stress Adaptation in the Global Biosphere and Its Implications	63
Basal Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches	62
Lipid Metabolism in Macrophages: Focus on Atherosclerosis	62
Mesenchymal Stem Cell-Derived Exosomes Ameliorate Alzheimer’s Disease Pathology and Improve Cognitive Deficits	62
The Role of Adipokines in Health and Disease	62
Flavonoids: Potential Candidates for the Treatment of Neurodegenerative Disorders	61
Battle Royale: Innate Recognition of Poxviruses and Viral Immune Evasion	60
Biomarkers and Utility of the Antioxidant Potential of Probiotic Lactobacilli and Bifidobacteria as Representatives of the Human Gut Microbiota	58
Oxidative Stress, Mitochondrial Dysfunction, and Neuroprotection of Polyphenols with Respect to Resveratrol in Parkinson’s Disease	58
Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs	58
Oxidative Stress in Ischemia/Reperfusion Injuries following Acute Ischemic Stroke	58