OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Translational Internal Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Acute kidney injury associated with severe hypouricemia caused by a novel SLC2A9 mutation: Enlightenment from rare disease to common disease	85
Comprehensive investigation of cuproptosis-related genes in clinical features, biological characteristics, and immune microenvironment in B-cell Non-Hodgkin lymphoma	67
Assessment of 17 clinically available renal biomarkers to predict acute kidney injury in critically ill patients	51
A Notch signaling pathway-related gene signature: Characterizing the immune microenvironment and predicting prognosis in hepatocellular carcinoma	42
Development and status quo of digestive endoscopy in China: An analysis based on the national census in 2013 and 2020	40
Standardized inhalation capability assessment: A key to optimal inhaler selection for inhalation therapy	38
Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients	37
Artificial intelligence for disease X: Progress and challenges	37
Reperfusion therapy for acute ischemic stroke: Where we are and where to go	35
Recognition of differently expressed genes and DNA methylation markers in patients with Lupus nephritis	34
The long and the short of current nanomedicines for treating Alzheimer's disease	31
Artificial intelligence in glycemic management for diabetes: Applications, opportunities and challenges	30
Immune checkpoint inhibitor-related endocrinopathies	29
Current applications and future perspectives of artificial intelligence in valvular heart disease	28
Role of viral hepatitis in pregnancy and its triggering mechanism	28
Development of a broadly potent neutralizing antibody targeting Nidogen 1 effectively inhibits cancer growth and metastasis in preclinical tumor models	26
Suggestions on home quarantine and recovery of novel coronavirus patients	26
Artificial intelligence in rheumatology: A transformative perspective	25
Insufficiency of quality of life as the treatment endpoint for balloon pulmonary angioplasty in inoperable chronic thromboembolic pulmonary hypertension	24
Senescent cells as a target for anti-aging interventions: From senolytics to immune therapies	23
Obesity and coronavirus disease 2019	23
Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway	23
Revising the hemodynamic criteria for pulmonary hypertension: A perspective from China	22
Prognostic value of serum ammonia in critical patients with non-hepatic disease: A prospective, observational, multicenter study	22
Monkeypox: Clinical issues of concern	22

Metabolic adaptation in lactation: Insulin-dependent and -independent glycemic control	21
A cycloruthenated complex, ruthenium (II) Z (RuZ) overcomes in vitro and in vivo multidrug resistance in cancer cells: A pivotal breakthrough	21
TCDD-inducible poly (ADP-ribose) polymerase promotes adipogenesis of both brown and white preadipocytes	19
Eupatilin unveiled: An in-depth exploration of research advancements and clinical therapeutic prospects	19
Could unpublishing negative results be harmful to the general public?	19
EV-Call 120: A new-generation emergency medical service system in China	19
Spatiotemporal analysis of the effects of exercise on the hemodynamics of the aorta in hypertensive rats using fluid-structure interaction simulation	18
Targeting regulated cell death: Apoptosis, necroptosis, pyroptosis, ferroptosis, and cuproptosis in anticancer immunity	18
Protective role of autophagy in triptolide-induced apoptosis of TM3 Leydig cells	17
Impact of the Alberta Stroke Program CT Score subregions on long-term functional outcomes in acute ischemic stroke: Results from two multicenter studies in China	17
Point-of-care ultrasound-guided submucosal paclitaxel injection in tracheal stenosis model	17
Mechanisms and treatment of atrial fibrillation and stroke	16
A multicenter, prospective, randomized, open-label, blinded endpoint trial of intravenous thrombolysis with tenecteplase for acute non-large vessel occlusion in extended time window (OPTION): Rational	16
Gastric electrical stimulation: Overview and summary	16
The evolution of folate supplementation – from one size for all to personalized, precision, poly-paths	16
Prehospital neuroprotective intervention: A critical imperative evidenced by the FRONTIER trial outcomes	16
Effect of local anti-vascular endothelial growth factor therapy to prevent the formation of stenosis in outflow vein in arteriovenous fistula	16
A similar effect of fibrinogen on efficacy and safety of tenecteplase versus alteplase in acute ischemic cerebrovascular events (TRACE II) trial	16
B10 cell-induced PD-L1/PD-1-linked macrophage polarization in periodontitis	16
Circular RNA: A promising new star of vaccine	15
Lipid-related protein NECTIN2 is an important marker in the progression of carotid atherosclerosis: An intersection of clinical and basic studies	15
Interpretation of the key issues of expert consensus on immunomodulatory therapies for chronic obstructive pulmonary disease	15
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells	14
CircPLK1 upregulates ETS1 to confer anthracycline resistance in triple-negative breast cancer	13
Monkeypox: A real new warning or just a sign of times?	13
The emergence of travel-related infections in critical care units	13
Relationship between homocysteine levels and post-stroke cognitive impairment in female and male population: from a prospective multicenter study	12
Prevalence and risk factors of hyperuricemia and gout: a cross-sectional survey from 31 provinces in mainland China	12
A generalized deep learning model for heart failure diagnosis using dynamic and static ultrasound	12
Biomarker development perspective: Exploring comorbid chronic pain in depression through deep transcranial magnetic stimulation	12
Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions	12
Harnessing the potential of small extracellular vesicle biomarkers for cancer diagnosis and prognosis with advanced analytical technologies	11
Right ventricle remodeling in chronic thromboembolic pulmonary hypertension	11
Exosomes and their derivatives as biomarkers and therapeutic delivery agents for cardiovascular diseases: Situations and challenges	11
Translational research in anti-pancreatic fibrosis drug discovery and development	10
Hypervolemia suppresses dilutional anaemic injury in a rat model of haemodilution	10
Antibiotic stewardship: Dead bugs do not mutate	10
Causal association between gut microbiota composition and the risk of atrial fibrillation	10
Adrenomedullin induces cisplatin chemoresistance in ovarian cancer through reprogramming of glucose metabolism	10
Network-guided neuromodulation for epilepsy: Unveiling the pathway to personalized therapy	10
Timing of anticoagulation for the management of portal vein thrombosis in liver cirrhosis	10
Single photon emission computed tomography/computed tomography imaging of gouty arthritis: A new voice	10
Endoscopic diagnosis and treatment of superficial non-ampullary duodenal epithelial tumors: A review	10
Effective albumin – A novel paradigm in the management of decompensated liver cirrhosis	10
Lnc5q21.2, a novel long intergenic RNA, sensitizes colorectal cancer cells to ATR inhibitor by activating Wnt pathway	9
Predicting survival for hepatic arterial infusion chemotherapy of unresectable colorectal liver metastases: Radiomics analysis of pretreatment computed tomography	9
Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines	9
Computational analyses to reveal the key determinants of the high malignancy level of cholangiocarcinoma	9
Characteristics of the severe acute respiratory syndrome coronavirus 2 omicron BA.2 subvariant in Jilin, China from March to May 2022	9
Single-nucleotide polymorphisms in medical nutritional weight loss: Challenges and future directions	9

The potential role of the brain–gut axis in the development and progression of Alzheimer's disease	9
Comparison of admission glycemic variability and glycosylated hemoglobin in predicting major adverse cardiac events among type 2 diabetes patients with heart failure following acute ST-segment elevati	9
Hyperchloremic metabolic acidosis post hysteroscopy: A place for balanced solutions?	8
Gastroesophageal reflux disease influences blood pressure components, lipid profile and cardiovascular diseases: Evidence from a Mendelian randomization study	8
The role of TIM3⁺ NK and TIM3^- NK cells in the immune pathogenesis of severe aplastic anemia	8
Emerging noninvasive neuromodulation methods for functional gastrointestinal diseases	8
Total and individual PBC-40 scores are reliable for the assessment of health-related quality of life in Greek patients with primary biliary cholangitis	8
Advances in the diagnosis and treatment of gastrointestinal tumors under the concept of super minimally invasive surgery	8
Chronic stress-induced immune dysregulation in breast cancer: Implications of psychosocial factors	8
Roles of noncoding RNAs in chronic obstructive pulmonary disease	8
Successful management of a high-risk acute myeloid leukemia patient with severe coronary heart disease by venetoclax plus azacytidine and coronary artery bypass grafting	8
Deciphering the role of ELAVL1: Insights from pan-cancer multiomics analyses with emphasis on nasopharyngeal carcinoma	7
Effectiveness and safety of Qixuekang Oral Liquid on vascular health	7
Comparison of predicting value of triglyceride‑glucose indices family in cardiovascular disease risk over time: Insights from a 9-year nationwide prospective cohort study	7
A pan-cancer analysis of the oncogenic role of Golgi transport 1B in human tumors	7
A first case report of using chimeric antigen receptor T-cell immunotherapy to treat high-risk smoldering multiple myeloma	7
Efficacy and safety of avatrombopag in aplastic anemia patients with liver disease	7
Hyperoxaluria: An early diagnosis will allow a timely combined renal and liver transplantations to avoid irreversible damages to all other organs	7
Secondary prevention for intracranial atherosclerotic stenosis: Where we stand and challenges ahead	7
A Case of abdominal pain and diarrhea post immunotherapy: Hypophysitis associated with immune checkpoint inhibitors	7
Association between anemia and 1-year recurrence of paroxysmal atrial fibrillation after radiofrequency ablation	6
The roles of subcellular Argonaute 2 in cardiovascular diseases	6
Predictors of progression in idiopathic inflammatory myopathies with interstitial lung disease	6
Machine learning-based phenogroups and prediction model in patients with functional gastrointestinal disorders to reveal distinct disease subsets associated with gas production	6
Global lineage evolution pattern of sars-cov-2 in Africa, America, Europe, and Asia: A comparative analysis of variant clusters and their relevance across continents	6
DEK-NUP214 monitoring before and after allogeneic haematopoietic stem cell transplantation for acute myeloid leukemia: A report from the TROPHY study group	6
Integrated network pharmacology and clinical study to reveal the efficacy and tolerability of Huoxue Tongjiang decoction for the treatment of non-erosive reflux disease-related symptoms	6
An international survey on the geographical differences in practice patterns and training of endoscopic ultrasound	6
Manipulating cell motility by Legionella: Speeding up or slowing down?	6
Extracorporeal membrane oxygenation using a modified cardiopulmonary bypass system	6
Retraction note: Hydrogel: A promising new technique for treating Alzheimer’s disease (in Volume 10 Issue 3)	6
Benefits of physical activity on cardiometabolic diseases in obese children and adolescents	5
Associations between serum sex steroid hormone metabolites and gastric cancer and precancerous lesions in men: A 11.8-year prospective study	5
The plakin family: Potential therapeutic targets for digestive system tumors	5
Induced pluripotent stem cells in the treatment of ischemic stroke	5
Serum myoglobin modulates kidney injury via inducing ferroptosis after exertional heatstroke	5
Dysregulation of miR-144-5p/RNF187 axis contributes to the progression of colorectal cancer	5
Evaluation of plasma vitamin E and development of proteinuria in hypertensive patients	5
NETosis and pyroptosis of immune cells in sepsis	5
Association of life’s essential 8 with prevalence and all-cause mortality of chronic kidney disease among US adults: Results from the National Health and Nutrition Examination Survey (2015–2018)	5
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis	5