OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Translational Internal Medicine is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Acute kidney injury associated with severe hypouricemia caused by a novel SLC2A9 mutation: Enlightenment from rare disease to common disease	113
Comprehensive investigation of cuproptosis-related genes in clinical features, biological characteristics, and immune microenvironment in B-cell Non-Hodgkin lymphoma	109
Co-targeting ferroptosis and immune evasion through small molecules in breast cancer	59
Standardized inhalation capability assessment: A key to optimal inhaler selection for inhalation therapy	57
Microvesicles derived from bone marrow and peripheral blood can reflect tumor load in multiple myeloma	56
A Notch signaling pathway-related gene signature: Characterizing the immune microenvironment and predicting prognosis in hepatocellular carcinoma	49
Artificial intelligence for disease X: Progress and challenges	47
Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients	46
Development and status quo of digestive endoscopy in China: An analysis based on the national census in 2013 and 2020	44
Protein kinase B is involved in bisphenol A-induced macrophage polarization through mechanistic target of rapamycin-dependent autophagy	42
Recognition of differently expressed genes and DNA methylation markers in patients with Lupus nephritis	39
Role of viral hepatitis in pregnancy and its triggering mechanism	38
Artificial intelligence in glycemic management for diabetes: Applications, opportunities and challenges	38
The long and the short of current nanomedicines for treating Alzheimer's disease	38
Reperfusion therapy for acute ischemic stroke: Where we are and where to go	37
Therapeutic potential of TMSC-Exo for non-alcoholic fatty liver disease using the liver-on-a-chip model	34
Current applications and future perspectives of artificial intelligence in valvular heart disease	32
Revising the hemodynamic criteria for pulmonary hypertension: A perspective from China	32
Obesity and coronavirus disease 2019	30
Suggestions on home quarantine and recovery of novel coronavirus patients	29
Insufficiency of quality of life as the treatment endpoint for balloon pulmonary angioplasty in inoperable chronic thromboembolic pulmonary hypertension	28
Senescent cells as a target for anti-aging interventions: From senolytics to immune therapies	27
Exosomes derived from Umbilical cord mesenchymal stem cell promote hair regrowth in C57BL6 mice through upregulation of the RAS/ERK signaling pathway	27
Development of a broadly potent neutralizing antibody targeting Nidogen 1 effectively inhibits cancer growth and metastasis in preclinical tumor models	27
Artificial intelligence in rheumatology: A transformative perspective	27

Monkeypox: Clinical issues of concern	26
Metabolic adaptation in lactation: Insulin-dependent and -independent glycemic control	26
Protocol for Chinese lung cancer evolution and microenvironment tracking under therapy study	25
A cycloruthenated complex, ruthenium (II) Z (RuZ) overcomes in vitro and in vivo multidrug resistance in cancer cells: A pivotal breakthrough	25
Association between free fatty acids and adverse outcomes in patients with and without diabetes undergoing percutaneous coronary intervention	24
The evolution of folate supplementation – from one size for all to personalized, precision, poly-paths	24
Eupatilin unveiled: An in-depth exploration of research advancements and clinical therapeutic prospects	24
Could unpublishing negative results be harmful to the general public?	24
Prognostic value of serum ammonia in critical patients with non-hepatic disease: A prospective, observational, multicenter study	24
Spatiotemporal analysis of the effects of exercise on the hemodynamics of the aorta in hypertensive rats using fluid-structure interaction simulation	23
Glue ablation therapy for patients with great saphenous vein varicosities: A randomized, parallel-controlled, multicenter, non-inferiority trial	22
Point-of-care ultrasound-guided submucosal paclitaxel injection in tracheal stenosis model	21
Protective role of autophagy in triptolide-induced apoptosis of TM3 Leydig cells	20
Impact of the Alberta Stroke Program CT Score subregions on long-term functional outcomes in acute ischemic stroke: Results from two multicenter studies in China	20
Targeting regulated cell death: Apoptosis, necroptosis, pyroptosis, ferroptosis, and cuproptosis in anticancer immunity	20
A similar effect of fibrinogen on efficacy and safety of tenecteplase versus alteplase in acute ischemic cerebrovascular events (TRACE II) trial	20
EV-Call 120: A new-generation emergency medical service system in China	20
Prehospital neuroprotective intervention: A critical imperative evidenced by the FRONTIER trial outcomes	19
Interpretation of the key issues of expert consensus on immunomodulatory therapies for chronic obstructive pulmonary disease	18
A multicenter, prospective, randomized, open-label, blinded endpoint trial of intravenous thrombolysis with tenecteplase for acute non-large vessel occlusion in extended time window (OPTION): Rational	18
Mechanisms and treatment of atrial fibrillation and stroke	18
Gastric electrical stimulation: Overview and summary	18
Anti-SIA-cIgG enhances chemotherapy effectiveness through PTPN13-regulated tumor stemness in head and neck squamous cell carcinoma	18
B10 cell-induced PD-L1/PD-1-linked macrophage polarization in periodontitis	17
CircPLK1 upregulates ETS1 to confer anthracycline resistance in triple-negative breast cancer	16
FOSL2 participates in renal fibrosis via SGK1-mediated epithelial-mesenchymal transition of proximal tubular epithelial cells	16
Circular RNA: A promising new star of vaccine	16
Monkeypox: A real new warning or just a sign of times?	15
The emergence of travel-related infections in critical care units	15
A generalized deep learning model for heart failure diagnosis using dynamic and static ultrasound	14
Predictive value of prognostic nutritional index for coronary heart disease: Evidence from a national population survey	14
Harnessing the potential of small extracellular vesicle biomarkers for cancer diagnosis and prognosis with advanced analytical technologies	14
Biomarker development perspective: Exploring comorbid chronic pain in depression through deep transcranial magnetic stimulation	14
Prevalence and risk factors of hyperuricemia and gout: a cross-sectional survey from 31 provinces in mainland China	14
"Zombie virus" like pyroptosis: Extracellular vesicles spread pyroptosis by transferring functional N-GSDMD pore	14
Dynamic loss of hormone receptors and reshaped drug sensitivity in male breast cancer organoids: A first case report and clinical implications	14
Feel the force: Biomechanical homeostasis of the cardiovascular system	13
Exosomes and their derivatives as biomarkers and therapeutic delivery agents for cardiovascular diseases: Situations and challenges	13
Focal adhesion kinase inhibition enhances response to checkpoint immunotherapy in hepatocellular carcinoma	12
Mitochondrial quality control as a therapeutic target in cardiovascular disease: Mechanistic insights and future directions	12
Hypervolemia suppresses dilutional anaemic injury in a rat model of haemodilution	12
International Conference on Translational Medicine 2025 Abstracts	12
Right ventricle remodeling in chronic thromboembolic pulmonary hypertension	12
Application of machine learning in risk stratification of obesity-related osteoarthritis: A study based on a nationally representative sample	12
Antibiotic stewardship: Dead bugs do not mutate	11
Timing of anticoagulation for the management of portal vein thrombosis in liver cirrhosis	11
Network-guided neuromodulation for epilepsy: Unveiling the pathway to personalized therapy	11
Metabolic reprogramming in neurodegenerative diseases: New insights into mTOR-mediated microglial polarization	11
Migrasome as a novel organelle: Biogenesis, physiological functions, and therapeutic potential	10
Causal association between gut microbiota composition and the risk of atrial fibrillation	10

Endotoxin retention in adipose tissue leading to persistent hypotension in catecholamine-dependent acute obstructive suppurative cholangitis	10
Adrenomedullin induces cisplatin chemoresistance in ovarian cancer through reprogramming of glucose metabolism	10
Add-on PD-1 inhibitor with Peg-IFNα therapy favors functional cure of chronic hepatitis B patients	10
Endoscopic diagnosis and treatment of superficial non-ampullary duodenal epithelial tumors: A review	10
Effective albumin – A novel paradigm in the management of decompensated liver cirrhosis	10
The potential role of the brain–gut axis in the development and progression of Alzheimer's disease	9
Postmenopausal osteoporosis and vascular calcification: The estrogen regulation network and calcification paradox	9
Lnc5q21.2, a novel long intergenic RNA, sensitizes colorectal cancer cells to ATR inhibitor by activating Wnt pathway	9
Single photon emission computed tomography/computed tomography imaging of gouty arthritis: A new voice	9
Characteristics of the severe acute respiratory syndrome coronavirus 2 omicron BA.2 subvariant in Jilin, China from March to May 2022	8
Computational analyses to reveal the key determinants of the high malignancy level of cholangiocarcinoma	8
Successful management of a high-risk acute myeloid leukemia patient with severe coronary heart disease by venetoclax plus azacytidine and coronary artery bypass grafting	8
Ferroptosis in organ fibrosis: From mechanisms to therapeutic medicines	8
Total and individual PBC-40 scores are reliable for the assessment of health-related quality of life in Greek patients with primary biliary cholangitis	8
Novel insights from a large cohort: Elucidating incidence, risk factors, treatment, and prognostic predictors in autoimmune hemolytic anemia after allogeneic hematopoietic stem cell transplantation	8
Gastroesophageal reflux disease influences blood pressure components, lipid profile and cardiovascular diseases: Evidence from a Mendelian randomization study	8
Chimeric degraders in neurodegenerative diseases: Challenges and future directions	8
Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors	8
SLC16A7 and WDR38 form a mitochondrial-centric axis driving lung cancer through metabolic reprogramming and REDOX adaptation	7
Emerging noninvasive neuromodulation methods for functional gastrointestinal diseases	7
PFKP binding AMOTL1 promotes tumor aerobic glycolysis and epithelial-mesenchymal transition by modulating Hippo pathway in head and neck cancer	7
Roles of noncoding RNAs in chronic obstructive pulmonary disease	7
Comparison of admission glycemic variability and glycosylated hemoglobin in predicting major adverse cardiac events among type 2 diabetes patients with heart failure following acute ST-segment elevati	7
Unfractionated heparin improves coagulation in sepsis by protecting glycocalyx of endothelia cells through inhibiting heparinase	7
Deciphering the role of ELAVL1: Insights from pan-cancer multiomics analyses with emphasis on nasopharyngeal carcinoma	7
Expression and clinical significance of growth differentiation factor-15 in vascular cognitive impairment based on bioinformatic analysis	7
The role of TIM3⁺ NK and TIM3^- NK cells in the immune pathogenesis of severe aplastic anemia	7
Association between falls and dementia risk: Evidence from three cohort studies	7
Advances in the diagnosis and treatment of gastrointestinal tumors under the concept of super minimally invasive surgery	7
Effectiveness and safety of Qixuekang Oral Liquid on vascular health	6
Association between anemia and 1-year recurrence of paroxysmal atrial fibrillation after radiofrequency ablation	6
Integrated network pharmacology and clinical study to reveal the efficacy and tolerability of Huoxue Tongjiang decoction for the treatment of non-erosive reflux disease-related symptoms	6
Efficacy and safety of avatrombopag in aplastic anemia patients with liver disease	6
Comparison of predicting value of triglyceride‑glucose indices family in cardiovascular disease risk over time: Insights from a 9-year nationwide prospective cohort study	6
Predictors of progression in idiopathic inflammatory myopathies with interstitial lung disease	6
A first case report of using chimeric antigen receptor T-cell immunotherapy to treat high-risk smoldering multiple myeloma	6
A pan-cancer analysis of the oncogenic role of Golgi transport 1B in human tumors	6
A Case of abdominal pain and diarrhea post immunotherapy: Hypophysitis associated with immune checkpoint inhibitors	6
Secondary prevention for intracranial atherosclerotic stenosis: Where we stand and challenges ahead	5
Extracorporeal membrane oxygenation using a modified cardiopulmonary bypass system	5
Manipulating cell motility by Legionella: Speeding up or slowing down?	5
Evaluation of plasma vitamin E and development of proteinuria in hypertensive patients	5
Retraction note: Hydrogel: A promising new technique for treating Alzheimer’s disease (in Volume 10 Issue 3)	5
Lactate modulates microglial M2 polarization via H3K9 lactylation in ischemic stroke	5
The roles of subcellular Argonaute 2 in cardiovascular diseases	5
Benefits of physical activity on cardiometabolic diseases in obese children and adolescents	5
An international survey on the geographical differences in practice patterns and training of endoscopic ultrasound	5
Machine learning-based phenogroups and prediction model in patients with functional gastrointestinal disorders to reveal distinct disease subsets associated with gas production	5
Global lineage evolution pattern of sars-cov-2 in Africa, America, Europe, and Asia: A comparative analysis of variant clusters and their relevance across continents	5
DEK-NUP214 monitoring before and after allogeneic haematopoietic stem cell transplantation for acute myeloid leukemia: A report from the TROPHY study group	5