OOIR: Observatory of International Research

Papers

(The H4-Index of Metabolites is 53. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Temperament Upregulates Mitochondrial Enzymes and Negatively Affects Myofibrillar Fragmentation in Beef of Excitable Bos taurus indicus Cattle	388
Metabolomic Analysis of Feces vs. Cecum Content in Animals: A Comparative Study Investigated by 1H-NMR	259
Gene Expression-Based Inference of Metabolic Signatures Reveals Distinct Molecular Profiles in Right- and Left-Sided Colon Cancer	198
Influence of Uric Acid on Vascular and Cognitive Functions: Evidence for an Ambivalent Relationship	188
Seed Metabolomic Landscape Reflecting Key Differential Metabolic Profiles Among Different Wheat Cultivars	176
The Detection of Primary Sclerosing Cholangitis Using Volatile Metabolites in Fecal Headspace and Exhaled Breath	170
Association of Nasopharyngeal and Serum Glutathione Metabolism with Bronchiolitis Severity and Asthma Risk: A Prospective Multicenter Cohort Study	144
Free Fatty Acids and Endotoxins Synergically Induce Pyroptosis in Bovine Hepatocytes	143
Caloric Restriction and Sirtuins as New Players to Reshape Male Fertility	134
Association of Trace Elements with Polycystic Ovary Syndrome in Women—A Case-Control Study	133
Changes in the Lipid Metabolism of the Longissimus thoracis Muscle in Bulls When Using Different Feeding Strategies during the Growing and Finishing Phases	127
Manifestations of Liver Impairment and the Effects of MH-76, a Non-Quinazoline α1-Adrenoceptor Antagonist, and Prazosin on Liver Tissue in Fructose-Induced Metabolic Syndrome	120
MSdeCIpher: A Tool to Link Data from Complementary Ionization Techniques in High-Resolution GC-MS to Identify Molecular Ions	119
Short-Term Standard Diet Consumption Prior to the Oral Fat Tolerance Test Modulates the Postprandial Triglyceride Response	115
Gastric Bypass Associated Hyperammonemia (GaBHA): A Case Study, Scoping Review of the Literature, and Proposed New Pathophysiologic Mechanism	106
Broussonetia papyrifera Pollen Metabolome Insights, Allergenicity, and Dispersal in Response to Climate Change Variables	103
Plasma Proteomics and Metabolomics of Aromatase Inhibitors-Related Musculoskeletal Syndrome in Early Breast Cancer Patients	100
Separate and Combined Effects of Moderate-Intensity Exercise Training and Detraining with Protocatechuic Acid (PCA) on Myokines and Insulin-Signaling Pathways in Male Wistar Rats: A Preclinical Random	99
Dietary Supplementation of Chestnut Tannins in Prepartum Dairy Cows Improves Antioxidant Defense Mechanisms Interacting with Thyroid Status	94
Postoperative Hyperuricemia—A Risk Factor in Elective Cardiosurgical Patients	94
Time-Resolved Metabolomics Reveals Mitochondrial Protection in Septic Liver Injury	94
A GC-MS Metabolic Study on Lipophilic Compounds in the Leaves of Common Wheat Triticum aestivum L.	91
Association Between Indole-3-Pyruvic Acid and Change in Fat-Free Mass Relative to Weight Loss in Patients Undergoing Sleeve Gastrectomy	88
Neurobiological Basis of Aversion-Resistant Ethanol Seeking in C. elegans	87
The Catalytic Domain of Neuropathy Target Esterase Influences Lipid Droplet Biogenesis and Lipid Metabolism in Human Neuroblastoma Cells	83

Editorial: Roles of the Circadian Rhythms in Metabolic Disease and Health	82
No Differences in Urine Bisphenol A Concentrations between Subjects Categorized with Normal Cognitive Function and Mild Cognitive Impairment Based on Montreal Cognitive Assessment Scores	82
Differentiation of the Organoleptic Volatile Organic Compound Profile of Three Edible Seaweeds	80
Development of an Untargeted Metabolomics Strategy to Study the Metabolic Rewiring of Dendritic Cells upon Lipopolysaccharide Activation	76
Comparison of Black Tea Waste and Legume Roughages: Methane Mitigation and Rumen Fermentation Parameters	75
Identification of Biomarkers for Methamphetamine Exposure Time Prediction in Mice Using Metabolomics and Machine Learning Approaches	72
Studies of Piper auritum Kuntz’s Mutagenic and Antimutagenic Properties Using the Ames Test	72
Fetal Exposure to Maternal Smoking and Neonatal Metabolite Profiles	71
Cerebral Glutamate Alterations Using Chemical Exchange Saturation Transfer Imaging in a Rat Model of Lipopolysaccharide-Induced Sepsis	71
Patients with Bacterial Sepsis Are Heterogeneous with Regard to Their Systemic Lipidomic Profiles	69
Molecular Mechanisms of Western Diet-Induced Obesity and Obesity-Related Carcinogenesis—A Narrative Review	68
Using Caprylic Acid for the Prevention and Treatment of Helicobacter pylori Infection and Gastric Cancer: A Review	66
Comparative Metabolomics Analysis of Gastrodia elata Blume Different Growth Stages: Insights into Chemical Composition and Bioactivities	65
Reduced Intra- and Extracellular Circulating Postprandial Lysosomal Acid Lipase Activity in Patients with MASLD	64
The Protective Effect of Docosahexaenoic Acid on Mitochondria in SH-SY5Y Model of Rotenone-Induced Toxicity	64
The Role of the Preanalytical Step for Human Saliva Analysis via Vibrational Spectroscopy	63
Taurine Facilitates the Formation of Hepatocellular Carcinoma via the Bile Acid Pathway	62
Optimization of the Fermentation Conditions of Huaniu Apple Cider and Quantification of Volatile Compounds Using HS-SPME-GC/MS	61
Correction: Lloyd et al. Chemical Diversity of UK-Grown Tea Explored Using Metabolomics and Machine Learning. Metabolites 2025, 15, 52	57
Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice	56
Non-Targeted Serum Lipidomics Analysis and Potential Biomarkers of Laryngeal Cancer Based on UHPLC-QTOF-MS	56
Non-Targeted Metabolomic Study of Fetal Growth Restriction	55
Cheminformatics Bioprospection of Broad Spectrum Plant Secondary Metabolites Targeting the Spike Proteins of Omicron Variant and Wild-Type SARS-CoV-2	55
HbA1c as a Continuous Marker of Microvascular Vulnerability: Development of a Non-Linear Risk Framework in a Real-World Cohort	54
Bioactive Compound Diversity in a Wide Panel of Sweet Potato (Ipomoea batatas L.) Cultivars: A Resource for Nutritional Food Development	54
Influence of Maternal Immune Activation and Stressors on the Hippocampal Metabolome	53
Associations of the Lipidome with Ageing, Cognitive Decline and Exercise Behaviours	53
Organic Trace Minerals Enhance the Gut Health of British Shorthair Cats by Regulating the Structure of Intestinal Microbiota	53
Gut Microbiota–Bile Acid Axis in Type 2 Diabetes–Associated Gallbladder Diseases: Mechanisms and Therapeutic Potential	53