OOIR: Observatory of International Research

Papers

(The TQCC of Life Sciences in Space Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Biofilm dynamics in space and their potential for sustainable space exploration – A comprehensive review	34
Anthocyanin can improve the survival of rice seeds from solar light outside the international space station	30
Challenges and innovations in food and water availability for a sustainable Mars colonization	28
3D culture and cryopreservation/thawing strategy of human induced pluripotent stem cells for spaceflight experiments	28
Organ dose equivalents of albedo protons and neutrons under exposure to large solar particle events during lunar human landing missions	22
IFC - Editorial Board	20
Results from the Radiation Assessment Detector on the International Space Station: Part 1, the Charged Particle Detector	18
Effect of countermeasure bodygear on cardiac-vascular-respiratory coupling during 6-degree head-down tilt: An earth-based microgravity study	18
RadLab: An open science resource for radiation studies relevant to human spaceflight	17
Domestication of Radiation Sensitive Caenorhabditis Elegans Strains Suitable For Liquid Culture Systems In Long-Term Space Mission	17
A no-fault risk compensation approach for radiation risks incurred in space travel	17
The case for anterior segment optical coherence tomography (AS-OCT) for the international space station and future planetary spaceflight: Clinical relevance and technical implementation	17
From Antarctic regolith to lunar greenhouses: Mechanistic insights into Brassica rapa photosystem II dynamics for sustainable space agriculture	17
Residual radiation risk disparities across sex and race or ethnic groups for lifetime never-smokers on lunar missions	16
Reorganization of the mouse oocyte' cytoskeleton after cultivation under simulated weightlessness	16
Comprehensive omics strategies for space agriculture development	16
IFC - Editorial Board	16
Radiation environment on TGO Mars orbit during solar particle events in January–October 2024. Corresponding solar eruptions and GOES proton fluxes data	15
Lignocellulose degradation, biogas production and characteristics of the microbial community in solid-state anaerobic digestion of wheat straw waste	15
Analysis of suitable site candidates for Mars human habitat and life-support technologies based on in situ water resource utilization	15
IFC - Editorial Board	15
Neuroprotective and neuromodulatory role of agmatine in mitigating simulated microgravity-induced cognitive and behavioral deficits in rats	13
Galactic cosmic ray environment predictions for the NASA BioSentinel Mission, part 2:Post-mission validation	13
Disparity in the effect of partial gravity simulated using a new apparatus on different rat hindlimb muscles	12
Construction of microgravity biological knowledge graph and its applications in anti-osteoporosis drug prediction	12

Comparative study of methods for detecting extraterrestrial life in exploration mission of Mars and the solar system	12
Optimizing autonomous artificial intelligence diagnostics for neuro-ocular health in space missions	12
Infrared spectroscopy reveals ethylene glycol is an anti-crystallizer in water mixed astrochemical ices	11
Behavior of simple closed ecological systems; lower nutrient concentrations allow longer persistence of grazer populations	11
The neurology of space flight; How does space flight effect the human nervous system?	10
High-throughput screening strategies for space-based radiation countermeasure discovery	10
Recent progresses on space life science research in China	10
A method to predict space radiation biological effectiveness for non-cancer effects following intense Solar Particle Events	9
The COSPAR Planetary Protection Policy for robotic missions to Mars: A review of current scientific knowledge and future perspectives	9
Study on primary physicochemical characteristics and nutrient adsorption of four plant cultivation substrates	9
Simulated microgravity altered the gene expression profiles and inhibited the proliferation of Kupffer cells in the early phase by downregulating LMO2 and EZH2	8
Pinoresinol diglucoside alleviates hindlimb unloading-induced bone loss in mice	8
Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans	8
Tissue-specific dose equivalents of secondary mesons and leptons during galactic cosmic ray exposures for mars exploration	8
Impact of weightlessness on dynamic deformation and haemodynamic parameters of the heart	8
Involvement of KATANIN1, a microtubule-severing enzyme, in hypergravity-induced modification of growth anisotropy in Arabidopsis hypocotyls	8
Transfer learning as an AI-based solution to address limited datasets in space medicine	7
IFC - Editorial Board	7
Accumulation of high-energy phosphates blocks the expression of mitochondrial biogenesis markers and slow-type myosin in soleus muscle under 24 hours of rat hindlimb suspension	7
Angiotensin converting enzyme (ACE) inhibitors as radiation countermeasures for long-duration space flights	7
Results from the Radiation Assessment Detector on the International Space Station, Part 2: The fast neutron detector	7
Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading	7
Microbes and nutrient shift in a Closed Aquatic Ecosystem (CAES) during four weeks of operation	7
Effects of social isolation and galactic cosmic radiation on fine motor skills and behavioral performance	7
Small tissue chips with big opportunities for space medicine	6
Parabolic flight as a research platform to investigate ophthalmic changes in microgravity	6
Reduced gravity effects on gait coordinative structures	6
Spaceflight validation of technology for point-of-care monitoring of peripheral blood WBC and differential in astronauts during space missions	6
IFC - Editorial Board	6
Medical countermeasures for the hematopoietic-subsyndrome of acute radiation syndrome in space	6
IFC - Editorial Board	6
Evolving radiological protection guidelines for exploration-class missions	6
Simulated space environmental factors of weightlessness, noise and low atmospheric pressure differentially affect the diurnal rhythm and the gut microbiome	6
Solid waste management and resource recovery during the 4-crew 180-day CELSS integrated experiment	6
Impact of gravitational forces on Red Blood Cell dynamics in biofluid suspension	6
Approaching ocular risks during spaceflight with 3D printing: Technical strategies to protect astronaut vision	6
Lower body negative pressure as a research tool and countermeasure for the physiological effects of spaceflight: A comprehensive review	5
IFC - Editorial Board	5
Active radiation measurements over one solar cycle with two DOSTEL instruments in the Columbus laboratory of the International Space Station	5
Parabolic flight as a space-flight analogon impacts angiogenesis and lipid metabolism	5
Comparison of the particle flux measured by Liulin-MO dosimeter in ExoMars TGO science orbit with those calculated by models	5
Corrigendum to ‘RadLab: An open science resource for radiation studies relevant to human spaceflight’ Life Sciences in Space Research Volume 43, November 2024, Pages 29-34	5
Sleep deprivation and glymphatic system dysfunction as a risk factor for SANS during long-duration spaceflight	5
Advancements in health monitoring technologies for astronauts in deep space missions: A Review	5
Biomechanics of healthy subjects during exercise on a simulated vibration isolation and stabilization system	5
IFC - Editorial Board	5
Cardiovascular adaptations in microgravity conditions	5
Improving astronaut cancer risk assessment from space radiation with an ensemble model framework	5
Leveraging lower body negative pressure for enhanced outcomes in orthopedic arthroplasty—Insights from NASA’s bone health research	5
Relationship of collagen as the component of the extracellular matrix with the mechanisms of autonomic regulation of the cardiovascular system under simulated conditions of long-term isolation	5

IFC - Editorial Board	5
Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice	5
Sleep deprivation and glymphatic dysfunction: Perspectives on the risk of Spaceflight Associated Neuro-ocular Syndrome (SANS)	5
Insights into the effect of microgravity on phytopathogens and plant-associated microbes	5
Mimic microgravity effect on muscle transcriptome under ionizing radiation	5
Effects of neutron radiation on pharmaceuticals in deep space-like environments - general anesthesia in space	5
Space biological and human survival: Investigations into plants, animals, microorganisms and their components and bioregenerative life support systems	5