OOIR: Observatory of International Research

Papers

(The TQCC of Life Sciences in Space Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
A review of astronaut mental health in manned missions: Potential interventions for cognitive and mental health challenges	38
The effects of microgravity on the digestive system and the new insights it brings to the life sciences	33
Applicability of composite materials for space radiation shielding of spacecraft	30
Biology and crop production in Space environments: Challenges and opportunities	29
Plant biology for space exploration – Building on the past, preparing for the future	24
Review of research into bioregenerative life support system(s) which can support humans living in space	24
Galactic cosmic ray simulation at the NASA space radiation laboratory – Progress, challenges and recommendations on mixed-field effects	21
Improving astronaut cancer risk assessment from space radiation with an ensemble model framework	21
Plant responses to real and simulated microgravity	21
Negative impact of disuse and unloading on tendon enthesis structure and function	20
Growth and photosynthetic responses of Chinese cabbage (Brassica rapa L. cv. Tokyo Bekana) to continuously elevated carbon dioxide in a simulated Space Station “Veggie” crop-production environment	20
Updated deterministic radiation transport for future deep space missions	20
Thick shielding against galactic cosmic radiation: A Monte Carlo study with focus on the role of secondary neutrons	19
Reversing radiation-induced immunosuppression using a new therapeutic modality	19
A proposed change to astronaut exposures limits is a giant leap backwards for radiation protection	19
Recent developments in space food for exploration missions: A review	18
Lignocellulose degradation, biogas production and characteristics of the microbial community in solid-state anaerobic digestion of wheat straw waste	18
A non-invasive approach to monitor anemia during long-duration spaceflight with retinal fundus images and deep learning	17
Small tissue chips with big opportunities for space medicine	16
The COSPAR Planetary Protection Policy for robotic missions to Mars: A review of current scientific knowledge and future perspectives	16
Gastrodia elata blume ameliorates circadian rhythm disorder-induced mice memory impairment	15
Transfer learning as an AI-based solution to address limited datasets in space medicine	14
Heavy ion space radiation triggers ongoing DNA base damage by downregulating DNA repair pathways	14
The neurology of space flight; How does space flight effect the human nervous system?	14
Long term food stability for extended space missions: a review	14

Identification of interstellar amino acetonitrile in the hot molecular core G10.47＋0.03: Possible glycine survey candidate for the future	14
Extended reality quantification of pupil reactivity as a non-invasive assessment for the pathogenesis of spaceflight associated neuro-ocular syndrome: A technology validation study for astronaut healt	14
Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen	13
Benchmarking risk predictions and uncertainties in the NSCR model of GCR cancer risks with revised low let risk coefficients	13
Private Spaceflight: A New Landscape for Dealing with Medical Risk	13
The Need for Biological Countermeasures to Mitigate the Risk of Space Radiation-Induced Carcinogenesis, Cardiovascular Disease, and Central Nervous System Deficiencies	13
Dynamic visual acuity as a biometric for astronaut performance and safety	12
Survival of desert algae Chlorella exposed to Mars-like near space environment	11
Application of functional microbial agent in aerobic composting of wheat straw for waste recycling	10
Advanced food packaging systems for space exploration missions	10
Population analysis of space travelers	9
Impact of galactic cosmic ray simulation on nutritional content of foods	9
Limb position sense and sensorimotor performance under conditions of weightlessness	9
The lack of mass transfer in bone lacunar-canalicular system may be the decisive factor of osteoporosis under microgravity	9
Effects of dietary aspirin on high-LET radiation-induced prostaglandin E2 levels and gastrointestinal tumorigenesis in Apc mice	9
What can space radiation protection learn from radiation oncology?	9
Crew time and workload in the EDEN ISS greenhouse in Antarctica	9
RRx-001 and the “Right stuff”: Protection and treatment in outer space	9
A novel device to study altered gravity and light interactions in seedling tropisms	9
Spaceflight validation of technology for point-of-care monitoring of peripheral blood WBC and differential in astronauts during space missions	9
Investigating alterations in the cellular envelope of Staphylococcus aureus in simulated microgravity using a random positioning machine	8
Characterization of exosome release and extracellular vesicle-associated miRNAs for human bronchial epithelial cells irradiated with high charge and energy ions	8
Breaking the limit: Biological countermeasures for space radiation exposure to enable long-duration spaceflight	8
Space radiation does not alter amyloid or tau pathology in the 3xTg mouse model of Alzheimer's disease	8
Targeting hippocampal neurogenesis to protect astronauts’ cognition and mood from decline due to space radiation effects	8
Aquatic invertebrate protein sources for long-duration space travel	8
Crew time in a space greenhouse using data from analog missions and Veggie	8
Suppression of endoplasmic reticulum stress prevents disuse muscle atrophy in a mouse model of microgravity	7
Comparison of two controlled-release fertilizer formulations for cut-and-come-again harvest yield and mineral content of Lactuca sativa L. cv. Outredgeous grown under International Space Station envir	7
Comparative study of methods for detecting extraterrestrial life in exploration mission of Mars and the solar system	7
Hybrid methods of radiation shielding against deep-space radiation	7
Effects of partial- or whole-body exposures to 56Fe particles on brain function and cognitive performance in rats	7
A new type of ground-based simulator of radiation field inside a spacecraft in deep space	7
Extracellular vesicles-derived microRNAs expression as biomarkers for neurological radiation injury: Risk assessment for space exploration	7
Cancer incidence risks above and below 1 Gy for radiation protection in space	7
Assessment of Spaceflight Medical Conditions’ and Treatments’ Potential Impacts on Behavioral Health and Performance	7
Looking on the horizon; potential and unique approaches to developing radiation countermeasures for deep space travel	7
Microgravity alters the expressions of DNA repair genes and their regulatory miRNAs in space-flown Caenorhabditis elegans	7
Baoyuan jieyu formula ameliorates depression-like behaviour in rats induced by simulated long-term spaceflight composite stress through regulating MAPK and BDNF pathways	6
Operation overview of a biological waste treatment system during the 4-crew 180-day integrated experiment in the controlled ecological life support system (CELSS)	6
Subsequent inclusion/exclusion criteria to select the best species for an experiment performed on the ISS in a refurbished hardware	6
Simulated weightlessness induces cognitive changes in rats illustrated by performance in operant conditioning tasks	6
The COSPAR planetary protection requirements for space missions to Venus	5
Effects of stepwise changes in dissolved carbon dioxide concentrations on metabolic activity in Chlorella for spaceflight applications	5
New evidence and insight for abnormalities in early embryonic development after short-term spaceflight onboard the Chinese SJ-10 satellite	5
Development of a NASA roadmap for planetary protection to prepare for the first human missions to Mars	5
Calculation of dose distribution in a realistic brain structure and the indication of space radiation influence on human brains	5
Mouse genomic associations with in vitro sensitivity to simulated space radiation	5
Real versus simulated galactic cosmic radiation for investigating cancer risk in the hematopoietic system - are we comparing apples to apples?	5
Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice	5

Observation of the radiation environment and solar energetic particle events in Mars orbit in May 2018- June 2022	5
Design and establishment of a large-scale controlled ecological life-support system integrated experimental platform	5
Proteomic analysis of the effects of simulated microgravity in human gastric mucosal cells	5
3D printing for space food applications: Advancements, challenges, and prospects	5
Comparison between PHITS and GEANT4 Simulations of the Heavy Ion Beams at the BEVALAC at LBNL and the Booster Accelerator at BNL	5
Nonhuman primate models in the study of spaceflight stressors: Past contributions and future directions	5
“Spaceflight-to-Eye Clinic”: Terrestrial advances in ophthalmic healthcare delivery from space-based innovations	5
Long-term pharmacological torpor of rats with feedback-controlled drug administration	5
Phenotypic and transcriptional changes in Escherichia coli K12 in response to simulated microgravity on the EagleStat, a new 2D microgravity analog for bacterial studies.	5