OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Orthopaedic Translation is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Chondrocyte ferroptosis contribute to the progression of osteoarthritis	171
Global, regional and national burden of low back pain 1990–2019: A systematic analysis of the Global Burden of Disease study 2019	161
Periosteum and development of the tissue-engineered periosteum for guided bone regeneration	69
Copper-based biomaterials for bone and cartilage tissue engineering	52
Exosomes derived from umbilical cord mesenchymal stem cells in mechanical environment show improved osteochondral activity via upregulation of LncRNA H19	40
Effectiveness and safety of biodegradable Mg-Nd-Zn-Zr alloy screws for the treatment of medial malleolar fractures	40
Molecular signaling in temporomandibular joint osteoarthritis	39
Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals	39
Fecal microbiota transplantation ameliorates bone loss in mice with ovariectomy-induced osteoporosis via modulating gut microbiota and metabolic function	38
Clinical applications and prospects of 3D printing guide templates in orthopaedics	36
Mussel-inspired extracellular matrix-mimicking hydrogel scaffold with high cell affinity and immunomodulation ability for growth factor-free cartilage regeneration	31
Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection	30
Cartilage tissue engineering for obesity-induced osteoarthritis: Physiology, challenges, and future prospects	30
Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration	28
Clinical study of 3D printed personalized prosthesis in the treatment of bone defect after pelvic tumor resection	28
Mechanical stimulation improves rotator cuff tendon-bone healing via activating IL-4/JAK/STAT signaling pathway mediated macrophage M2 polarization	27
HURWA robotic-assisted total knee arthroplasty improves component positioning and alignment – A prospective randomized and multicenter study	26
3D printing metal implants in orthopedic surgery: Methods, applications and future prospects	26
Molecular mechanisms of osteogenesis and antibacterial activity of Cu-bearing Ti alloy in a bone defect model with infection in vivo	26
Neurotropin exerts neuroprotective effects after spinal cord injury by inhibiting apoptosis and modulating cytokines	26
Low-intensity pulsed ultrasound inhibits fibroblast-like synoviocyte proliferation and reduces synovial fibrosis by regulating Wnt/β-catenin signaling	25
Identification of circ-FAM169A sponges miR-583 involved in the regulation of intervertebral disc degeneration	25
Clinical translation of a patient-specific scaffold-guided bone regeneration concept in four cases with large long bone defects	25
Wearable robotic exoskeleton for gait reconstruction in patients with spinal cord injury: A literature review	25
An overview of polyester/hydroxyapatite composites for bone tissue repairing	24

Osteochondral tissue engineering: Perspectives for clinical application and preclinical development	24
Association between hypertension and osteoarthritis: A systematic review and meta-analysis of observational studies	24
Immobilization of bioactive vascular endothelial growth factor onto Ca-deficient hydroxyapatite-coated Mg by covalent bonding using polydopamine	24
PLGA/β-TCP composite scaffold incorporating cucurbitacin B promotes bone regeneration by inducing angiogenesis	22
Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity?	22
Complex joint-preserving bone tumor resection and reconstruction using computer navigation and 3D-printed patient-specific guides: A technical note of three cases	22
General recommendation for assessment and management on the risk of glucocorticoid-induced osteonecrosis in patients with COVID-19	21
The role of osteocytes-specific molecular mechanism in regulation of mechanotransduction – A systematic review	21
Differential gene expression profile by RNA sequencing study of elderly osteoporotic hip fracture patients with sarcopenia	21
Biodegradable magnesium implant enhances angiogenesis and alleviates medication-related osteonecrosis of the jaw in rats	21
3D gel-printed porous magnesium scaffold coated with dibasic calcium phosphate dihydrate for bone repair in vivo	21
Development of degradable magnesium-based metal implants and their function in promoting bone metabolism (A review)	20
Early treadmill running delays rotator cuff healing via Neuropeptide Y mediated inactivation of the Wnt/β-catenin signaling	20
Controlled growth factor delivery system with osteogenic-angiogenic coupling effect for bone regeneration	20
Dual-functional hybrid quaternized chitosan/Mg/alginate dressing with antibacterial and angiogenic potential for diabetic wound healing	20
Evolutionary course of the femoral head osteonecrosis: Histopathological - radiologic characteristics and clinical staging systems	20
Role of peroxiredoxin 6 in the chondroprotective effects of microvesicles from human adipose tissue-derived mesenchymal stem cells	19
Modified tibial transverse transport technique for the treatment of ischemic diabetic foot ulcer in patients with type 2 diabetes	18
Tibial cortex transverse transport facilitating healing in patients with recalcitrant non-diabetic leg ulcers	18
Puerarin specifically disrupts osteoclast activation via blocking integrin-β3 Pyk2/Src/Cbl signaling pathway	18
Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds	18
One strike loading organ culture model to investigate the post-traumatic disc degenerative condition	18
Mesenchymal stem cells and macrophages and their interactions in tendon-bone healing	18
Cyasterone accelerates fracture healing by promoting MSCs migration and osteogenesis	18
Satisfactory long-term survival, functional and radiological outcomes of open-wedge high tibial osteotomy for managing knee osteoarthritis: Minimum 10-year follow-up study	17
Potential of different cells-derived exosomal microRNA cargos for treating spinal cord injury	17
Reconstruction with customized, 3D-printed prosthesis after resection of periacetabular Ewing’s sarcoma in children using "triradiate cartilage-based" surgical strategy:a technical note	17
Therapeutics for enhancement of spinal fusion: A mini review	17
Kindlin-2 deletion in osteoprogenitors causes severe chondrodysplasia and low-turnover osteopenia in mice	17
Parathyroid hormone (1–34) can reverse the negative effect of valproic acid on the osseointegration of titanium rods in ovariectomized rats	17
Forkhead box O3 attenuates osteoarthritis by suppressing ferroptosis through inactivation of NF-κB/MAPK signaling	16
Modulating macrophage polarization for the enhancement of fracture healing, a systematic review	16
3D ultrasound imaging provides reliable angle measurement with validity comparable to X-ray in patients with adolescent idiopathic scoliosis	16
Effect of tibial cortex transverse transport in patients with recalcitrant diabetic foot ulcers: A prospective multicenter cohort study	16
Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model	16
Effect of book-shaped acellular tendon scaffold with bone marrow mesenchymal stem cells sheets on bone–tendon interface healing	16
Exosomes secreted by hypoxia-stimulated bone-marrow mesenchymal stem cells promote grafted tendon-bone tunnel healing in rat anterior cruciate ligament reconstruction model	16
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis	16
A novel tissue-engineered bone graft composed of silicon-substituted calcium phosphate, autogenous fine particulate bone powder and BMSCs promotes posterolateral spinal fusion in rabbits	15
One-stage debridement and bone transport versus first-stage debridement and second-stage bone transport for the management of lower limb post-traumatic osteomyelitis	15
Bilayered scaffold with 3D printed stiff subchondral bony compartment to provide constant mechanical support for long-term cartilage regeneration	15
An update to the advances in understanding distraction histogenesis: From biological mechanisms to novel clinical applications	14
The protective effect of DNA aptamer on osteonecrosis of the femoral head by alleviating TNF-α-mediated necroptosis via RIP1/RIP3/MLKL pathway	14
Exosome-based strategy for degenerative disease in orthopedics: Recent progress and perspectives	14
Combination of cobalt, chromium and titanium nanoparticles increases cytotoxicity in vitro and pro-inflammatory cytokines in vivo	14
ZnO nanoparticles attenuate polymer-wear-particle induced inflammatory osteolysis by regulating the MEK-ERK-COX-2 axis	14
Comminuted patellar fractures: The role of biplanar fixed angle plate constructs	14
Regulated cell death: Implications for intervertebral disc degeneration and therapy	14
Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice	14
Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor	13

Recommendations on the post-acute management of the osteoporotic fracture - Patients with “very-high” Re-fracture risk	13
Chinese Association of Orthopaedic Surgeons (CAOS) clinical guideline for the treatment of diabetic foot ulcers using tibial cortex transverse transport technique (version 2020)	13
MFG-E8 promotes tendon-bone healing by regualting macrophage efferocytosis and M2 polarization after anterior cruciate ligament reconstruction	13
Cyclooxygenase-2 regulates PTHrP transcription in human articular chondrocytes and is involved in the pathophysiology of osteoarthritis in rats	13
An osteoarthritis subtype characterized by synovial lipid metabolism disorder and fibroblast-like synoviocyte dysfunction	13
Computational optimisation of screw orientations for improved locking plate fixation of proximal humerus fractures	13
Irisin promotes fracture healing by improving osteogenesis and angiogenesis	13
Automatic phantom-less QCT system with high precision of BMD measurement for osteoporosis screening: Technique optimisation and clinical validation	13
Losartan protects against osteoarthritis by repressing the TGF-β1 signaling pathway via upregulation of PPARγ	13
Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis	13
Bone tissue engineering scaffolds with HUVECs/hBMSCs cocultured on 3D-printed composite bioactive ceramic scaffolds promoted osteogenesis/angiogenesis	13
Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model	13
A static magnetic field enhances the repair of osteoarthritic cartilage by promoting the migration of stem cells and chondrogenesis	13
ECFC-derived exosomal THBS1 mediates angiogenesis and osteogenesis in distraction osteogenesis via the PI3K/AKT/ERK pathway	12
New physiological insights into the phenomena of deer antler: A unique model for skeletal tissue regeneration	12
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway	12
Exploring the translational potential of clusterin as a biomarker of early osteoarthritis	12
Comprehensive analysis of N6-methyladenosine (m6A) modification during the degeneration of lumbar intervertebral disc in mice	12
Biomaterial-based scaffolds in promotion of cartilage regeneration: Recent advances and emerging applications	12
Inflammatory mechanisms linking obesity and tendinopathy	12
Identification and diagnosis of meniscus tear by magnetic resonance imaging using a deep learning model	12
Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: State of the art	12
The effect of traumatic brain injury on bone healing from a novel exosome centered perspective in a mice model	12
Verification and clinical translation of a newly designed “Skywalker” robot for total knee arthroplasty: A prospective clinical study	12
3D printed porous sulfonated polyetheretherketone scaffold for cartilage repair: Potential and limitation	12
Osteocyte β1 integrin loss causes low bone mass and impairs bone mechanotransduction in mice	12
Associations of osteoclastogenesis and nerve growth in subchondral bone marrow lesions with clinical symptoms in knee osteoarthritis	12
Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation	11
Hemodynamic stress shapes subchondral bone in osteoarthritis: An emerging hypothesis	11
Osseointegrated prostheses for the rehabilitation of patients with transfemoral amputations: A prospective ten-year cohort study of patient-reported outcomes and complications	11
De-osteogenic-differentiated mesenchymal stem cells accelerate fracture healing by mir-92b	11
Evaluation of animal models and methods for assessing shoulder function after rotator cuff tear: A systematic review	11
Effect of porosity of a functionally-graded scaffold for the treatment of corticosteroid-associated osteonecrosis of the femoral head in rabbits	11
Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice	11
Potential and recent advances of microcarriers in repairing cartilage defects	11
Exercised accelerated the production of muscle-derived kynurenic acid in skeletal muscle and alleviated the postmenopausal osteoporosis through the Gpr35/NFκB p65 pathway	11
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects	11
Is dexamethasone-induced muscle atrophy an alternative model for naturally aged sarcopenia model?	11
Construction of biomimetic cell-sheet-engineered periosteum with a double cell sheet to repair calvarial defects of rats	11
Krüppel like factor 10 prevents intervertebral disc degeneration via TGF-β signaling pathway both in vitro and in vivo	11