OOIR: Observatory of International Research

Papers

(The H4-Index of Stem Cell Reports is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Genome-wide analyses reveal the detrimental impacts of SARS-CoV-2 viral gene Orf9c on human pluripotent stem cell-derived cardiomyocytes	199
Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layers	190
A regulatory role for CHD4 in maintenance of the spermatogonial stem cell pool	158
Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies	96
Reconstruction of dynamic regulatory networks reveals signaling-induced topology changes associated with germ layer specification	96
Putting Science into Standards workshop on standards for organ-on-chip	92
Deriving waveform parameters from calcium transients in human iPSC-derived cardiomyocytes to predict cardiac activity with machine learning	91
Effect of Notch1 signaling on muscle engraftment and maturation from pluripotent stem cells	84
Improved hematopoietic stem cell transplantation upon inhibition of natural killer cell-derived interferon-gamma	83
A versatile in vivo platform for reversible control of transgene expression in adult tissues	81
Patients' perspectives on the derivation and use of organoids	79
Silencing of p53 and CDKN1A establishes sustainable immortalized megakaryocyte progenitor cells from human iPSCs	78
MSCohi-O lenses for long-term retention of mesenchymal stem cells on ocular surface as a therapeutic approach for chronic ocular graft-versus-host disease	73
Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2	69
YAP signaling in horizontal basal cells promotes the regeneration of olfactory epithelium after injury	67
Dissecting the impact of differentiation stage, replicative history, and cell type composition on epigenetic clocks	66
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes	65
Ribosomal proteins regulate 2-cell-stage transcriptome in mouse embryonic stem cells	64
Familial Alzheimer’s disease-associated PSEN1 mutations affect neurodevelopment through increased Notch signaling	55
USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development	55
In and out: Benchmarking in vitro, in vivo, ex vivo, and xenografting approaches for an integrative brain disease modeling pipeline	54
Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells	54
Connie Eaves (1944–2024)	50
Bone morphogenetic protein 4 induces hematopoietic stem cell development from murine hemogenic endothelial cells in culture	50
Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation	49

Human spinal GABA neurons survive and mature in the injured nonhuman primate spinal cord	48
Gains of 20q11.21 in human pluripotent stem cells: Insights from cancer research	48
ISSCR’s Guidelines for Stem Cell Research and Clinical Translation: Supporting development of safe and efficacious stem cell-based interventions	46
Differentiation success of reprogrammed cells is heterogeneous in vivo and modulated by somatic cell identity memory	46
Single-cell characterization of neovascularization using hiPSC-derived endothelial cells in a 3D microenvironment	45
DOT1L regulates lung developmental epithelial cell fate and adult alveolar stem cell differentiation after acute injury	45
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency	44
Single-cell approaches define two groups of mammalian oligodendrocyte precursor cells and their evolution over developmental time	44
Upregulation of the JAK-STAT pathway promotes maturation of human embryonic stem cell-derived cardiomyocytes	42
IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock	41
Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects	41
Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium	40
Functionally redundant roles of ID family proteins in spermatogonial stem cells	40
Plasticity of ocular surface epithelia: Using a murine model of limbal stem cell deficiency to delineate metaplasia and transdifferentiation	39
Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2	39