Redox Biology

Papers
(The median citation count of Redox Biology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Special issue on ‘Biomarkers of Oxidative Stress, Aging and Nutrition in Human Studies’341
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins312
OXPHOS inhibition overcomes chemoresistance in triple negative breast cancer261
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation244
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology232
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing220
Coronin 1a-mediated F-actin disassembly controls effector function in murine neutrophils205
Fullerol rescues the light-induced retinal damage by modulating Müller glia cell fate203
A quantitative proteomic approach to evaluate the efficacy of carnosine in a murine model of chronic obstructive pulmonary disease (COPD)183
The influence of vitamin D supplementation and strength training on health biomarkers and chromosomal damage in community-dwelling older adults180
Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure171
Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma170
GAPDH inhibition mediated by thiol oxidation in human airway epithelial cells exposed to an environmental peroxide167
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice167
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion166
The mammalian peroxisomal membrane is permeable to both GSH and GSSG – Implications for intraperoxisomal redox homeostasis165
TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCα-NOX4 axis163
Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle162
Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain161
Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia159
Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma157
A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice148
Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases144
PM2.5-induced iron homeostasis imbalance triggers cardiac hypertrophy through ferroptosis in a selective autophagy crosstalk manner141
Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis139
Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults139
Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage139
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis136
Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control134
Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins133
The protective role of GPX4 in naïve ESCs is highlighted by induced ferroptosis resistance through GPX4 expression133
Thioredoxin (Trx): A redox target and modulator of cellular senescence and aging-related diseases131
Oxidative stress response and NRF2 signaling pathway in autism spectrum disorder130
SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential128
The antioxidant and oxidant properties of hydropersulfides (RSSH) and polysulfide species126
Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation125
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores124
Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation122
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO120
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease117
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc116
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress114
Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies114
Organic Selenium induces ferroptosis in pancreatic cancer cells112
Apolipoprotein E is required for brain iron homeostasis in mice111
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53–P21/Nrf2 activation in a HuR-dependent m6A manner107
CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway107
Glutathione peroxidase 3 is essential for countering senescence in adipose remodelling by maintaining mitochondrial homeostasis103
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer103
Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway102
Selenium deficiency impedes maturation of parvalbumin interneurons, perineuronal nets, and neural network activity99
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress99
Endothelial peroxynitrite causes disturbance of neuronal oscillations by targeting caspase-1 in the arcuate nucleus98
HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease98
Inhibition of mitochondrial complex I leading to NAD+/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an integrative analysis of platelet bioenergetics an97
Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics97
A model of mitochondrial superoxide production during ischaemia-reperfusion injury for therapeutic development and mechanistic understanding95
New insights into extracellular and intracellular redox status in COVID-19 patients95
Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis94
Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion91
DRD4 alleviates acute kidney injury by suppressing ISG15/NOX4 axis-associated oxidative stress91
Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs90
Accumulation of acetaldehyde in aldh2.1 zebrafish causes increased retinal angiogenesis and impaired glucose metabolism90
Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation90
Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]88
Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy88
Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols88
An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria88
Retraction notice to “Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell” [Redox Biol. 11 (2017) 322–334]87
Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus87
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction87
Cytoglobin scavenges intracellular hydrogen peroxide and regulates redox signals in the vasculature86
Dietary sulfur amino acid restriction in humans with overweight and obesity: Evidence of an altered plasma and urine sulfurome, and a novel metabolic signature that correlates with loss of fat mass an86
Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-1185
Role of DDX1 in the oxidative response of ataxia telangiectasia patient-derived fibroblasts85
Acute stimulation of glucose metabolism by H2O2 sustains the NADPH steady-state under oxidative stress84
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death84
REV-ERBα regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF284
Fatty acid nitroalkene reversal of established lung fibrosis83
Redox shuttle of cytosolic Thioredoxin to mitochondria protects against hyperoxia-mediated alteration of mitochondrial structure and dysfunction83
The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury83
Supplement-driven iron overload accelerates phenotypic aging via inflammatory biomarkers: Potential counteraction through anti-inflammatory or antioxidant diets83
Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1–7)-Mas-mediated macrophage polarization82
Development of nitroalkene-based inhibitors to target STING-dependent inflammation81
PM2.5 increases susceptibility to acute exacerbation of COPD via NOX4/Nrf2 redox imbalance-mediated mitophagy80
Disulfide stress and its role in cardiovascular diseases80
A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation79
Mitochondrial cholesterol: Metabolism and impact on redox biology and disease78
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M278
Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis77
Poor glycaemic control in type 2 diabetes compromises leukocyte oxygen consumption rate, OXPHOS complex content and neutrophil-endothelial interactions77
Sweroside alleviates pressure overload-induced heart failure through targeting CaMKⅡδ to inhibit ROS-mediated NF-κB/NLRP3 in cardiomyocytes76
HDAC11 negatively regulates antifungal immunity by inhibiting Nos2 expression via binding with transcriptional repressor STAT376
ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis76
CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease75
Deadly excess copper75
An essential role for EROS in redox-dependent endothelial signal transduction74
Discovery of genomic loci for liver health and steatosis reveals overlap with glutathione redox genetics74
Nox2-derived superoxide radical is crucial to control acute Trypanosoma cruzi infection73
Accumulation of endogenous adenosine improves cardiomyocyte metabolism via epigenetic reprogramming in an ischemia-reperfusion model73
Long noncoding RNA MAGI2-AS3 regulates the H2O2 level and cell senescence via HSPA873
Viral inactivation of murine coronavirus via multiple gas plasma-derived reactive species73
Modulation of recovery from neonatal hyperoxic lung injury by sex as a biological variable72
Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis71
Vanadium pentoxide induced oxidative stress and cellular senescence in human lung fibroblasts71
GHSR deficiency exacerbates Parkinson's disease pathology by impairing autophagy71
Interaction between redox regulation, immune activation, and response to treatment in HER2+ breast cancer71
Ceruloplasmin deletion in myelinating glial cells induces myelin disruption and oxidative stress in the central and peripheral nervous systems70
Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density70
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin70
Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo70
Isoginkgetin, a bioactive constituent from Ginkgo Biloba, protects against obesity-induced cardiomyopathy via enhancing Nrf2/ARE signaling70
Cold plasma and inhibition of STAT3 selectively target tumorigenicity in osteosarcoma70
TMBIM6 deficiency leads to bone loss by accelerating osteoclastogenesis69
Epigenetically upregulated NSUN2 confers ferroptosis resistance in endometrial cancer via m5C modification of SLC7A11 mRNA69
Was hydrogen peroxide present before the arrival of oxygenic photosynthesis? The important role of iron(II) in the Archean ocean69
NADPH-oxidases as potential pharmacological targets for thrombosis and depression comorbidity68
DNA dioxygenases TET2 deficiency promotes cigarette smoke induced chronic obstructive pulmonary disease by inducing ferroptosis of lung epithelial cell68
NCF4 dependent intracellular reactive oxygen species regulate plasma cell formation68
Insulin oxidation and oxidative modifications alter glucose uptake, cell metabolism, and inflammatory secretion profiles67
HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence66
Mass spectrometry-based direct detection of multiple types of protein thiol modifications in pancreatic beta cells under endoplasmic reticulum stress65
RAGE promotes dysregulation of iron and lipid metabolism in alcoholic liver disease64
Nanotherapies for sepsis by regulating inflammatory signals and reactive oxygen and nitrogen species: New insight for treating COVID-1964
A potent phosphodiester Keap1-Nrf2 protein-protein interaction inhibitor as the efficient treatment of Alzheimer's disease64
Carbon monoxide-loaded red blood cells ameliorate metabolic dysfunction-associated steatohepatitis progression via enhancing AMP-activated protein kinase activity and inhibiting Kupffer cell activatio63
Chenodeoxycholic acid suppresses AML progression through promoting lipid peroxidation via ROS/p38 MAPK/DGAT1 pathway and inhibiting M2 macrophage polarization63
TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes63
Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury63
PAR level mediates the link between ROS and inflammatory response in patients with type 2 diabetes mellitus62
Mitochondrial network dynamics in pulmonary disease: Bridging the gap between inflammation, oxidative stress, and bioenergetics61
Loss of NAMPT and SIRT2 but not SIRT1 attenuate GLO1 expression and activity in human skeletal muscle61
Redox homeostasis in cardiac fibrosis: Focus on metal ion metabolism61
Hydrogen sulfide protects cardiomyocytes from doxorubicin-induced ferroptosis through the SLC7A11/GSH/GPx4 pathway by Keap1 S-sulfhydration and Nrf2 activation60
Role of metabolomics in the delivery of precision nutrition60
Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics59
Cysteine trisulfide oxidizes protein thiols and induces electrophilic stress in human cells59
The loss of pancreatic islet NADPH oxidase (NOX)2 improves islet transplantation59
An orally active carbon monoxide-releasing molecule enhances beneficial gut microbial species to combat obesity in mice58
An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver58
Retraction notice to: Macrophage SAMSN1 protects against sepsis-induced acute lung injury in mice [Redox Biol. 56 (2022) 102432]58
Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells58
Corrigendum to “Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission” [Redox Biol. 15 (2018) 335–346]58
iPSC-derived cardiomyocytes and engineered heart tissues reveal suppressed JAK2/STAT3 signaling in LMNA-related emery-dreifuss muscular dystrophy57
SENP3 sensitizes macrophages to ferroptosis via de-SUMOylation of FSP157
Hepatic Regulator of G Protein Signaling 6 (RGS6) drives non-alcoholic fatty liver disease by promoting oxidative stress and ATM-dependent cell death57
Induction of 2-hydroxycatecholestrogens O-methylation: A missing puzzle piece in diagnostics and treatment of lung cancer56
Impaired lipid homeostasis and elevated lipid oxidation of erythrocyte membrane in adolescent depression56
The glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 656
Suppression of ATG4B by copper inhibits autophagy and involves in Mallory body formation55
Defence Warriors: Exploring the crosstalk between polyamines and oxidative stress during microbial pathogenesis55
Liver-secreted FGF21 induces sarcopenia by inhibiting satellite cell myogenesis via klotho beta in decompensated cirrhosis55
Radiosensitizing capacity of fenofibrate in glioblastoma cells depends on lipid metabolism55
Combinatorial lipidomics and proteomics underscore erythrocyte lipid membrane aberrations in the development of adverse cardio-cerebrovascular complications in maintenance hemodialysis patients54
Estradiol-mediated small GTP-binding protein GDP dissociation stimulator induction contributes to sex differences in resilience to ferroptosis in takotsubo syndrome54
The establishment of mitotic errors-driven senescence depends on autophagy54
Myosin light-chain 4 gene-transfer attenuates atrial fibrosis while correcting autophagic flux dysregulation54
Redox-sensitive epigenetic activation of SUV39H1 contributes to liver ischemia-reperfusion injury54
The extracellular Ero1α/PDI electron transport system regulates platelet function by increasing glutathione reduction potential53
Activation of Nrf2 inhibits atherosclerosis in ApoE mice through suppressing endothelial cell inflammation and lipid peroxidation53
Riboflavin kinase binds and activates inducible nitric oxide synthase to reprogram macrophage polarization53
GPX4 deficiency-induced ferroptosis drives endometrial epithelial fibrosis in polycystic ovary syndrome53
Human mitochondrial peroxiredoxin Prdx3 is dually localized in the intermembrane space and matrix subcompartments52
Hypoxia increases persulfide and polysulfide formation by AMP kinase dependent cystathionine gamma lyase phosphorylation52
The selenoprotein P/ApoER2 axis facilitates selenium accumulation in selenoprotein P-accepting cells and confers prolonged resistance to ferroptosis52
Proteome-wide quantitative analysis of redox cysteine availability in the Drosophila melanogaster eye reveals oxidation of phototransduction machinery during blue light exposure and age52
Reactive oxygen species generation by reverse electron transfer at mitochondrial complex I under simulated early reperfusion conditions52
Oxime blot: A novel method for reliable and sensitive detection of carbonylated proteins in diverse biological systems52
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities51
Modulating antioxidant systems as a therapeutic approach to retinal degeneration51
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates mitochondrial dysfunction via PI3K/Akt/eNOS signaling pathway in diabetic tubulopathy51
Cellular and exosomal GPx1 are essential for controlling hydrogen peroxide balance and alleviating oxidative stress in hypoxic glioblastoma51
M6A demethylase ALKBH5 regulates FOXO1 mRNA stability and chemoresistance in triple-negative breast cancer51
The mechanism and significance of the conversion of xanthine dehydrogenase to xanthine oxidase in mammalian secretory gland cells51
Nitro-Oleic acid protects from neovascularization, oxidative stress, gliosis and neurodegeneration in oxygen-induced retinopathy51
Redox regulation of DUBs and its therapeutic implications in cancer50
Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKα1/ULK1/FUNDC1/mitophagy pathway50
Nrf2: An all-rounder in depression50
Metabolic reprogramming, oxidative stress, and pulmonary hypertension50
Nlrp6 protects from corticosterone-induced NSPC ferroptosis by modulating RIG-1/MAVS-mediated mitophagy49
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions49
ROS-Drp1-mediated mitochondria fission contributes to hippocampal HT22 cell apoptosis induced by silver nanoparticles49
A role for the cystathionine-β-synthase /H2S axis in astrocyte dysfunction in the aging brain49
Antrodia cinnamomea triterpenoids attenuate cardiac hypertrophy via the SNW1/RXR/ALDH2 axis49
Hypobaric hypoxia-driven energy metabolism disturbance facilitates vascular endothelial dysfunction48
Inhibition of MST1 ameliorates neuronal apoptosis via GSK3β/β-TrCP/NRF2 pathway in spinal cord injury accompanied by diabetes48
Tryptanthrin targets GSTP1 to induce senescence and increases the susceptibility to apoptosis by senolytics in liver cancer cells48
Interplay between epigenetics, senescence and cellular redox metabolism in cancer and its therapeutic implications48
Immunoediting of KEAP1-NRF2 mutant tumours is required to circumvent NRF2-mediated immune surveillance47
Corrigendum to “Hyperoxia induces glucose metabolism reprogramming and intracellular acidification by suppressing MYC/MCT1 axis in lung cancer” [Redox Biol. 61 (2023) 102647]47
A targetable PRR11-DHODH axis drives ferroptosis- and temozolomide-resistance in glioblastoma47
Targeting the aryl hydrocarbon receptor by gut phenolic metabolites: A strategy towards gut inflammation47
Omega-3 fatty acids and individual variability in plasma triglyceride response: A mini-review47
The KEAP1-NRF2 pathway: Targets for therapy and role in cancer47
The mitochondria-targeted sulfide delivery molecule attenuates drugs-induced gastropathy. Involvement of heme oxygenase pathway.46
Apoptotic breast cancer cells after chemotherapy induce pro-tumour extracellular vesicles via LAP-competent macrophages46
Corrigendum to “Cellular redox imbalance on the crossroad between mitochondrial dysfunction, senescence, and proliferation” [Redox Biol. 53 (2022) 102337]46
SOD2 in skeletal muscle: New insights from an inducible deletion model46
Corrigendum to “Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family” [Redox Biol. 37 (2020 Sep 6)46
Thiosulfate sulfurtransferase deficiency promotes oxidative distress and aberrant NRF2 function in the brain46
Corrigendum to “Mfn2-mediated mitochondrial fusion alleviates doxorubicin-induced cardiotoxicity with enhancing its anticancer activity through metabolic switch” [Redox Biol. 52 (2022) 1–16/102311]46
Enhancing HIF-1α–P2X2 signaling in dorsal raphe serotonergic neurons promotes psychological resilience45
Corrigendum to “LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats” [Redox Biol. 21 (2019) 101121]45
Comments on “was hydrogen peroxide present before the arrival of oxygenic photosynthesis? The important role of iron(II) in the archean ocean”45
Redox and actin, a fascinating story45
Corrigendum to “A novel anti-atherosclerotic mechanism of quercetin: Competitive binding to KEAP1 via Arg483 to inhibit macrophage pyroptosis” [Redox Biol. 57 (2022) 102511]45
Mutant Nrf2E79Q enhances the promotion and progression of a subset of oncogenic Ras keratinocytes and skin tumors45
Deletion of cystathionine-γ-lyase in bone marrow-derived cells promotes colitis-associated carcinogenesis44
Mechanism of action of platinum nanoparticles implying from antioxidant to metabolic programming in light-induced retinal degeneration model44
Melatonin protects aged oocytes from depalmitoylation-mediated quality reduction by promoting PPT1 degradation and antioxidation44
Inhibition of ethanol-induced eNAMPT secretion attenuates liver ferroptosis through BAT-Liver communication44
Vitamin C deficiency induces hypoglycemia and cognitive disorder through S-nitrosylation-mediated activation of glycogen synthase kinase 3β44
Dimethyl malonate preserves renal and mitochondrial functions following ischemia-reperfusion via inhibition of succinate dehydrogenase43
Red blood cell-derived microparticles induce kidney injury by triggering endothelial cell ferroptosis in intravascular hemolysis43
Development of an assay pipeline for the discovery of novel small molecule inhibitors of human glutathione peroxidases GPX1 and GPX443
Identification of peroxiredoxin 6 as a direct target of withangulatin A by quantitative chemical proteomics in non-small cell lung cancer43
Long-term senolytic therapy with Dasatinib and Quercetin alleviates lipofuscin-dependent retinal degeneration in mice43
NCOA4 linked to endothelial cell ferritinophagy and ferroptosis:a key regulator aggravate aortic endothelial inflammation and atherosclerosis42
DHODH-mediated mitochondrial redox homeostasis: a novel ferroptosis regulator and promising therapeutic target42
Inhibition of glutathione peroxidase 4 suppresses gastric cancer peritoneal metastasis via regulation of RCC2 homeostasis41
Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis41
ASIC1a senses lactate uptake to regulate metabolism in neurons41
FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms41
Effects of chronic dietary nitrate supplementation on longevity, vascular function and cancer incidence in rats41
Excessive linoleic acid induces muscle oxidative stress through 5-lipoxygenase-dependent peroxidation41
Functional diversity of YbbN/CnoX proteins: Insights from a comparative analysis of three thioredoxin-like oxidoreductases from Pseudomonas aeruginosa, Xylella fastidiosa and Escherichia coli41
Hypoxia and the endometrium: An indispensable role for HIF-1α as therapeutic strategies41
Bilirubin deficiency renders mice susceptible to hepatic steatosis in the absence of insulin resistance41
HDLBP-stabilized lncFAL inhibits ferroptosis vulnerability by diminishing Trim69-dependent FSP1 degradation in hepatocellular carcinoma40
Glucoraphanin and sulforaphane mitigate TNFα-induced Caco-2 monolayers permeabilization and inflammation40
Intestinal polyphenol antioxidant activity involves redox signaling mechanisms facilitated by aquaporin activity40
Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques40
Sigma-1 receptor agonist PRE-084 confers protection against TAR DNA-binding protein-43 toxicity through NRF2 signalling40
Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl mouse model triggers retinal degeneration pathways upon acute light stress40
Inhibition of KDM4A restricts SQLE transcription and induces oxidative stress imbalance to suppress bladder cancer40
Exercise protects aged mice against coronary endothelial senescence via FUNDC1-dependent mitophagy40
Mechano-signaling via Piezo1 prevents activation and p53-mediated senescence of muscle stem cells40
Effects of methionine intake on cognitive function in mild cognitive impairment patients and APP/PS1 Alzheimer's Disease model mice: Role of the cystathionine-β-synthase/H2S pathway39
Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection39
Sirt5 improves cardiomyocytes fatty acid metabolism and ameliorates cardiac lipotoxicity in diabetic cardiomyopathy via CPT2 de-succinylation39
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma39
Thioredoxin TRXo1 is involved in ABA perception via PYR1 redox regulation39
Mitochondrial aldehyde dehydrogenase-2 coordinates the hydrogen sulfide - AMPK axis to attenuate high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system39
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis38
Regulation of FSP1 myristoylation by NADPH: A novel mechanism for ferroptosis inhibition38
Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches38
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress38
Pharmacological activation of GPX4 ameliorates doxorubicin-induced cardiomyopathy38
TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells38
17β-oestradiol inhibits ferroptosis in the hippocampus by upregulating DHODH and further improves memory decline after ovariectomy38
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