OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 81. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
The protective role of GPX4 in naïve ESCs is highlighted by induced ferroptosis resistance through GPX4 expression	415
Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice	326
GAPDH inhibition mediated by thiol oxidation in human airway epithelial cells exposed to an environmental peroxide	295
Special issue on ‘Biomarkers of Oxidative Stress, Aging and Nutrition in Human Studies’	281
bFGF alleviates diabetes-associated endothelial impairment by downregulating inflammation via S-nitrosylation pathway	274
Cooperation between CYB5R3 and NOX4 via coenzyme Q mitigates endothelial inflammation	265
Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins	233
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins	222
Mechano-activated connexin hemichannels and glutathione transport protect lens fiber cells against oxidative insults	215
Glutathione peroxidase 3 is essential for countering senescence in adipose remodelling by maintaining mitochondrial homeostasis	213
A quantitative proteomic approach to evaluate the efficacy of carnosine in a murine model of chronic obstructive pulmonary disease (COPD)	210
A promising drug repurposing approach for Alzheimer's treatment: Givinostat improves cognitive behavior and pathological features in APP/PS1 mice	204
The mammalian peroxisomal membrane is permeable to both GSH and GSSG – Implications for intraperoxisomal redox homeostasis	200
Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia	195
Loss of selenoprotein W in murine macrophages alters the hierarchy of selenoprotein expression, redox tone, and mitochondrial functions during inflammation	188
Cell cycle induction in human cardiomyocytes is dependent on biosynthetic pathway activation	183
Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation	181
Human ultrarare genetic disorders of sulfur metabolism demonstrate redundancies in H2S homeostasis	173
Fullerol rescues the light-induced retinal damage by modulating Müller glia cell fate	172
G protein β5-ATM complexes drive acetaminophen-induced hepatotoxicity	170
The influence of vitamin D supplementation and strength training on health biomarkers and chromosomal damage in community-dwelling older adults	164
Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control	152
Skeletal muscle-specific Keap1 disruption modulates fatty acid utilization and enhances exercise capacity in female mice	150
Loss of Selenov predisposes mice to extra fat accumulation and attenuated energy expenditure	148
PM2.5-induced iron homeostasis imbalance triggers cardiac hypertrophy through ferroptosis in a selective autophagy crosstalk manner	146

CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway	145
Coronin 1a-mediated F-actin disassembly controls effector function in murine neutrophils	143
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress	141
NADPH oxidase 1: A target in the capacity of dimeric ECG and EGCG procyanidins to inhibit colorectal cancer cell invasion	141
Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing	140
Dimethyl fumarate ameliorates erectile dysfunction in bilateral cavernous nerve injury rats by inhibiting oxidative stress and NLRP3 inflammasome-mediated pyroptosis of nerve via activation of Nrf2/HO	140
Mitochondria spatially and temporally modulate VSMC phenotypes via interacting with cytoskeleton in cardiovascular diseases	131
Autophagy activation is required for N6-methyladenosine modification to regulate ferroptosis in hepatocellular carcinoma	131
Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer	130
SOD2 orchestrates redox homeostasis in intervertebral discs: A novel insight into oxidative stress-mediated degeneration and therapeutic potential	129
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53–P21/Nrf2 activation in a HuR-dependent m6A manner	128
Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease	128
ROS promote hyper-methylation of NDRG2 promoters in a DNMTS-dependent manner: Contributes to the progression of renal fibrosis	126
An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology	125
Connexin hemichannels regulate redox potential via metabolite exchange and protect lens against cellular oxidative damage	123
Integrated regulation of stress responses, autophagy and survival by altered intracellular iron stores	119
Reductively modified albumin attenuates DSS-Induced mouse colitis through rebalancing systemic redox state	119
Organic Selenium induces ferroptosis in pancreatic cancer cells	119
Artemether confers neuroprotection on cerebral ischemic injury through stimulation of the Erk1/2-P90rsk-CREB signaling pathway	115
Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies	113
Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle	110
TRPM7 channel inhibition attenuates rheumatoid arthritis articular chondrocyte ferroptosis by suppression of the PKCα-NOX4 axis	110
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress	110
Synergistic induction of ferroptosis by targeting HERC1-NCOA4 axis to enhance the photodynamic sensitivity of osteosarcoma	109
Inhibition of spinal ferroptosis-like cell death alleviates hyperalgesia and spontaneous pain in a mouse model of bone cancer pain	108
SIRT1 attenuates blood-spinal cord barrier disruption after spinal cord injury by deacetylating p66Shc	107
The antioxidant and oxidant properties of hydropersulfides (RSSH) and polysulfide species	106
Thioredoxin (Trx): A redox target and modulator of cellular senescence and aging-related diseases	106
Lipid peroxidation derived reactive carbonyl species in free and conjugated forms as an index of lipid peroxidation: limits and perspectives	106
Apolipoprotein E is required for brain iron homeostasis in mice	104
Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion	101
Selenium deficiency impedes maturation of parvalbumin interneurons, perineuronal nets, and neural network activity	101
Dietary sulfur amino acid restriction in humans with overweight and obesity: Evidence of an altered plasma and urine sulfurome, and a novel metabolic signature that correlates with loss of fat mass an	101
Nutrigenomics and redox regulation: Concepts relating to the Special Issue on nutrigenomics	101
HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease	100
Accumulation of acetaldehyde in aldh2.1 zebrafish causes increased retinal angiogenesis and impaired glucose metabolism	100
CircSV2b participates in oxidative stress regulation through miR-5107-5p-Foxk1-Akt1 axis in Parkinson's disease	100
New insights into extracellular and intracellular redox status in COVID-19 patients	99
Inactivation of RIP3 kinase sensitizes to 15LOX/PEBP1-mediated ferroptotic death	99
Deadly excess copper	96
Fatty acid nitroalkene reversal of established lung fibrosis	95
The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury	93
Inhibition of mitochondrial complex I leading to NAD+/NADH imbalance in type 2 diabetic patients who developed late stent thrombosis: Evidence from an integrative analysis of platelet bioenergetics an	93
Endothelial peroxynitrite causes disturbance of neuronal oscillations by targeting caspase-1 in the arcuate nucleus	90
An ACE2/Mas-related receptor MrgE axis in dopaminergic neuron mitochondria	89
Glutathione-S-transferase P promotes glycolysis in asthma in association with oxidation of pyruvate kinase M2	89
Myeloid ACE2 protects against septic hypotension and vascular dysfunction through Ang-(1–7)-Mas-mediated macrophage polarization	87
Disulfide stress and its role in cardiovascular diseases	87
DRD4 alleviates acute kidney injury by suppressing ISG15/NOX4 axis-associated oxidative stress	87
A thiol redox sensor in soluble epoxide hydrolase enables oxidative activation by intra-protein disulfide bond formation	86

Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2−)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864]	85
Recovery of reduced thiol groups by superoxide-mediated denitrosation of nitrosothiols	84
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction	83
Genetic engineering of circularly permuted yellow fluorescent protein reveals intracellular acidification in response to nitric oxide stimuli	82
Compensatory expression of NRF2-dependent antioxidant genes is required to overcome the lethal effects of Kv11.1 activation in breast cancer cells and PDOs	81
Release of hepatic xanthine oxidase (XO) to the circulation is protective in intravascular hemolytic crisis	81