OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases	328
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy	251
The diverse functionality of NQO1 and its roles in redox control	231
Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies	201
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer	186
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury	180
Oxidative eustress: On constant alert for redox homeostasis	179
PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer	177
HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration	171
Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis	165
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells	155
Xanthine oxidoreductase: One enzyme for multiple physiological tasks	150
Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics	150
N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells	145
Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury	142
Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis	141
The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function	140
Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology	139
Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis	139
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker	137
Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases	137
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence	136
Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway	134
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury	130
Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3	128

Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia	124
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway	122
Short-chain fatty acids as modulators of redox signaling in health and disease	121
Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis	120
Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism	115
FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury	112
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities	111
Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes	110
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction	110
Inhibition of APOC1 promotes the transformation of M2 into M1 macrophages via the ferroptosis pathway and enhances anti-PD1 immunotherapy in hepatocellular carcinoma based on single-cell RNA sequencin	108
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation	106
Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury	105
Induction of autophagy via the ROS-dependent AMPK-mTOR pathway protects copper-induced spermatogenesis disorder	104
Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension	104
Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKα1/ULK1/FUNDC1/mitophagy pathway	104
Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control	103
Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation	103
Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injur	103
Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer	100
The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury	99
Immune cell - produced ROS and their impact on tumor growth and metastasis	98
Ergothioneine, recent developments	98
Protease-activated receptor 2 induces ROS-mediated inflammation through Akt-mediated NF-κB and FoxO6 modulation during skin photoaging	96
The Nrf2 induction prevents ferroptosis in Friedreich's Ataxia	95
Epigallocatechin-3-gallate pretreatment alleviates doxorubicin-induced ferroptosis and cardiotoxicity by upregulating AMPKα2 and activating adaptive autophagy	93
Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α signaling pathway to alleviate the early brain injury of subara	92
Irisin ameliorates doxorubicin-induced cardiac perivascular fibrosis through inhibiting endothelial-to-mesenchymal transition by regulating ROS accumulation and autophagy disorder in endothelial cells	90
Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway	89
Parkinson's disease: Alterations in iron and redox biology as a key to unlock therapeutic strategies	88
Ubiquitination and receptor-mediated mitophagy converge to eliminate oxidation-damaged mitochondria during hypoxia	88
Medical gas plasma-stimulated wound healing: Evidence and mechanisms	88
Interactions of zinc- and redox-signaling pathways	85
The Nrf2-NLRP3-caspase-1 axis mediates the neuroprotective effects of Celastrol in Parkinson's disease	85
Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions	83
Roles of selenoprotein S in reactive oxygen species-dependent neutrophil extracellular trap formation induced by selenium-deficient arteritis	81
Resolving the paradox of ferroptotic cell death: Ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis	79
Glutaredoxin: Discovery, redox defense and much more	79
U-shaped association of uric acid to overall-cause mortality and its impact on clinical management of hyperuricemia	78
The role of NADPH oxidases in infectious and inflammatory diseases	78
Redox changes in obesity, metabolic syndrome, and diabetes	78
TRIM22 inhibits osteosarcoma progression through destabilizing NRF2 and thus activation of ROS/AMPK/mTOR/autophagy signaling	76
The lncRNA Malat1 regulates microvascular function after myocardial infarction in mice via miR-26b-5p/Mfn1 axis-mediated mitochondrial dynamics	76
Role of acetylation in doxorubicin-induced cardiotoxicity	74
LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss	73
miR-125b-5p in adipose derived stem cells exosome alleviates pulmonary microvascular endothelial cells ferroptosis via Keap1/Nrf2/GPX4 in sepsis lung injury	73
Aspirin promotes RSL3-induced ferroptosis by suppressing mTOR/SREBP-1/SCD1-mediated lipogenesis in PIK3CA-mutant colorectal cancer	72
Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus	71
MitoQ protects against hyperpermeability of endothelium barrier in acute lung injury via a Nrf2-dependent mechanism	71
Inhibition of ferroptosis and iron accumulation alleviates pulmonary fibrosis in a bleomycin model	71