OOIR: Observatory of International Research

Papers

(The H4-Index of Redox Biology is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement	496
Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications	376
Lactate as a fulcrum of metabolism	276
Micro- and nano-plastics activation of oxidative and inflammatory adverse outcome pathways	237
NOX4 promotes ferroptosis of astrocytes by oxidative stress-induced lipid peroxidation via the impairment of mitochondrial metabolism in Alzheimer's diseases	232
Physical activity and exercise: Strategies to manage frailty	226
Oxidative stress-based therapeutics in COPD	204
The aryl hydrocarbon receptor as a target of environmental stressors – Implications for pollution mediated stress and inflammatory responses	194
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis	184
Complex interplay between autophagy and oxidative stress in the development of pulmonary disease	182
Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy	172
The diverse functionality of NQO1 and its roles in redox control	169
NLRP3 inflammasome-mediated pyroptosis contributes to the pathogenesis of non-ischemic dilated cardiomyopathy	166
Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway	162
Interrelation between ROS and Ca2+ in aging and age-related diseases	161
Oxidative stress pathways of air pollution mediated toxicity: Recent insights	150
HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury	149
Iron dyshomeostasis, lipid peroxidation and perturbed expression of cystine/glutamate antiporter in Alzheimer’s disease: Evidence of ferroptosis	148
PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer	146
Oxidative eustress: On constant alert for redox homeostasis	145
ROS systems are a new integrated network for sensing homeostasis and alarming stresses in organelle metabolic processes	143
Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies	139
Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis	132
Prediction of survival odds in COVID-19 by zinc, age and selenoprotein P as composite biomarker	130
Mitigation of the replication of SARS-CoV-2 by nitric oxide in vitro	128

Meteorin-like protein attenuates doxorubicin-induced cardiotoxicity via activating cAMP/PKA/SIRT1 pathway	127
Identification of Frataxin as a regulator of ferroptosis	127
FBW7-NRA41-SCD1 axis synchronously regulates apoptosis and ferroptosis in pancreatic cancer cells	125
Effects of hydrogen sulfide on mitochondrial function and cellular bioenergetics	124
Plant catalases as NO and H2S targets	122
Estrogenic control of mitochondrial function	121
Innate-adaptive immunity interplay and redox regulation in immune response	120
The m6A reader YTHDC2 inhibits lung adenocarcinoma tumorigenesis by suppressing SLC7A11-dependent antioxidant function	119
Selenium and selenoproteins in viral infection with potential relevance to COVID-19	118
HO-1-mediated ferroptosis as a target for protection against retinal pigment epithelium degeneration	116
Curcumin blunts epithelial-mesenchymal transition of hepatocytes to alleviate hepatic fibrosis through regulating oxidative stress and autophagy	116
Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury	115
Nox2 activation in Covid-19	109
N6-methyladenosine modification regulates ferroptosis through autophagy signaling pathway in hepatic stellate cells	108
ACSL4 deficiency confers protection against ferroptosis-mediated acute kidney injury	106
Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer	106
Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction	105
Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer	104
Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis	103
Fibroblast growth factor 21 attenuates iron overload-induced liver injury and fibrosis by inhibiting ferroptosis	102
Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights	102
Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis	101
Xanthine oxidoreductase: One enzyme for multiple physiological tasks	100
Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence	100
A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation	100
Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia	99
Expression profiling meta-analysis of ACE2 and TMPRSS2, the putative anti-inflammatory receptor and priming protease of SARS-CoV-2 in human cells, and identification of putative modulators	99
Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases	99
Sex differences in inflammation, redox biology, mitochondria and autoimmunity	98
Polysulfide-mediated sulfhydration of SIRT1 prevents diabetic nephropathy by suppressing phosphorylation and acetylation of p65 NF-κB and STAT3	98
Breaking the vicious loop between inflammation, oxidative stress and coagulation, a novel anti-thrombus insight of nattokinase by inhibiting LPS-induced inflammation and oxidative stress	97
Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis	97
Redox toxicology of environmental chemicals causing oxidative stress	97
Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology	97
Nitric oxide in cellular adaptation and disease	95
The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells	94
Exercise and dietary intervention ameliorate high-fat diet-induced NAFLD and liver aging by inducing lipophagy	93
Restoration of L-OPA1 alleviates acute ischemic stroke injury in rats via inhibiting neuronal apoptosis and preserving mitochondrial function	93
Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions	90
Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control	89
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway	87
FUNDC1-dependent mitophagy induced by tPA protects neurons against cerebral ischemia-reperfusion injury	87
Elucidating the contribution of mitochondrial glutathione to ferroptosis in cardiomyocytes	87
Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway	86
The role of selenium in type-2 diabetes mellitus and its metabolic comorbidities	86
Quiescin sulfhydryl oxidase 1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by driving EGFR endosomal trafficking and inhibiting NRF2 activation	86
Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II–induced hypertension	85
Short-chain fatty acids as modulators of redox signaling in health and disease	85
Protective role of microglial HO-1 blockade in aging: Implication of iron metabolism	85
Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular endothelial cells after traumatic spinal cord injur	85

Iron overload in the motor cortex induces neuronal ferroptosis following spinal cord injury	83
Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction	82
Ergothioneine, recent developments	81
SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis	81
Extracellular superoxide dismutase, a molecular transducer of health benefits of exercise	80
The role of nitric oxide in brain disorders: Autism spectrum disorder and other psychiatric, neurological, and neurodegenerative disorders	80