OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Metabolism is 47. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3	318
Nutrient control of splice site selection contributes to methionine addiction of cancer	229
Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice	186
ACAA1 knockout increases the survival rate of KPC mice by activating autophagy	159
Reprogramming hormone-sensitive prostate cancer to a lethal neuroendocrine cancer lineage by mitochondrial pyruvate carrier (MPC)	130
Physical training reduces cell senescence and associated insulin resistance in skeletal muscle	108
Genetic and sex-specific regulation of mitochondrial function in gonadal and inguinal adipose tissue	100
DYRK1A inhibition restores pancreatic functions and improves glucose metabolism in a preclinical model of type 2 diabetes	98
Deletion of the mitochondrial calcium uniporter in adipose tissue promotes energy expenditure and alleviates diet-induced obesity	98
TGF-β antagonism synergizes with PPARγ agonism to reduce fibrosis and enhance beige adipogenesis	95
Acute inhibition of hunger-sensing AgRP neurons promotes context-specific learning in mice	86
Depletion of pyruvate kinase (PK) activity causes glycolytic intermediate imbalances and reveals a PK-TXNIP regulatory axis	83
Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions	83
Dysregulated systemic metabolism in a Down syndrome mouse model	78
GPSM1 in POMC neurons impairs brown adipose tissue thermogenesis and provokes diet-induced obesity	77
Beta-hydroxybutyrate dampens adipose progenitors’ profibrotic activation through canonical Tgfβ signaling and non-canonical ZFP36-dependent mechanisms	76
Neuronal miR-29a protects from obesity in adult mice	74
Endothelial TrkA coordinates vascularization and innervation in thermogenic adipose tissue and can be targeted to control metabolism	72
10 years of Molecular Metabolism	71
Lysine tRNA fragments and miR-194-5p co-regulate hepatic steatosis via β-Klotho and perilipin 2	70
Genome-wide meta-analysis of 92 cardiometabolic protein serum levels	68
Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP	66
TGR5 receptors in SF1-expressing neurons of the ventromedial hypothalamus regulate glucose homeostasis	65
Aregs-IGFBP3-mediated SMC-like cells apoptosis impairs beige adipocytes formation in aged mice	65
VGluT3 BNST neurons transmit GABA and restrict sucrose consumption	64

Bioenergetic adaptations of small intestinal epithelial cells reduce cell differentiation enhancing intestinal permeability in obese mice	63
JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism	63
RNA binding proteins PCBP1 and PCBP2 regulate pancreatic β cell translation	63
NFE2L1-mediated proteasome function protects from ferroptosis	61
From type 1 diabetes biology to therapy: The Human Islet Research Network	58
The physiology of experimental overfeeding in animals	57
The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR	57
Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling	56
Declining muscle NAD+ in a hyperandrogenism PCOS mouse model: Possible role in metabolic dysregulation	54
Daily running enhances molecular and physiological circadian rhythms in skeletal muscle	54
Hemostatic alterations linked to body fat distribution, fatty liver, and insulin resistance	53
Emerging molecular technologies for light-mediated modulation of pancreatic beta-cell function	52
KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic rats	52
Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice	52
Exercise-induced specialized proresolving mediators stimulate AMPK phosphorylation to promote mitochondrial respiration in macrophages	52
Endothelial BBSome is essential for vascular, metabolic, and retinal functions	51
The liver clock modulates circadian rhythms in white adipose tissue	50
GLP-1 physiology informs the pharmacotherapy of obesity	49
Peroxiredoxin 2 regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing	49
Sestrin2 maintains hepatic immune homeostasis and redox balance partially via inhibiting RIPK3-mediated necroptosis in metabolic dysfunction-associated steatohepatitis	47
Apolipoprotein A-IV is induced by high-fat diets and mediates positive effects on glucose and lipid metabolism	47
Corrigendum to “Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis” [Mol Metab 69 (2023) 1–13]	47
UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity	47