Journal of Bone Oncology

Article	Citations
Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation	53
Fracture risk in breast cancer: Does obesity have an effect? A scoping review	44
Langerhans Cell Histiocytosis: A Population-based Study of Anatomical Distribution and Treatment Patterns	36
Discharge status and post-discharge healthcare costs after skeletal-related event hospitalizations among medicare patients with bone metastatic solid tumors or multiple myeloma	32
Bones and guts – Why the microbiome matters	30
Role of the osteocyte in bone metastasis – The importance of networking	28
Macrophage heterogeneity in bone metastasis	26
Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy – Observational prospective single institution analysis	24
Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms	22
Impact of adjuvant imatinib on bone and muscle density in patients with resected gastrointestinal stromal tumors	22
Prosthesis or osteosynthesis for the treatment of a pathological hip fracture? A nationwide registry-based cohort study	19
Prognostic factors and survival of patients undergoing surgical intervention for breast cancer bone metastases	18
Deep learning-based magnetic resonance imaging of the spine in the diagnosis and physiological evaluation of spinal metastases	18
The impact of androgen deprivation therapy on bone microarchitecture in men with prostate cancer: A longitudinal observational study (The ANTELOPE Study)	18
Automated measurement of lumbar pedicle screw parameters using deep learning algorithm on preoperative CT scans	18
Study of imaging changes following preoperative denosumab for giant cell tumor of bone	17
Emerging roles for stromal cells in bone metastasis	17
Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression	16
#21. PD-1 blockade induces bone loss and reduces bone strength in a breast cancer bone metastasis model	16
#9. Inhibition of the fatty acid binding proteins (FABPs) in myeloma cells modifies their lipid composition	15
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells	15
#45. Fatty acid binding proteins may modulate myeloma in Fabp4/5 double knockout mouse	15
#37. Lactate-GPR81 signaling in acute myeloid leukemia (AML) contributes to bone marrow microenvironment dysfunction, macrophage polarization, and leukemia cell growth	15
#43. Long-chain acyl-CoA synthetases support multiple myeloma cell proliferation, survival and mitochondrial function	14
#33. PTHrP biological domains differentially regulate breast tumor intracrine signaling independent of nuclear localization	14

#15. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma	13
#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer	13
#42. Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing	13
CDK4/6 inhibitor and doxorubicin synergistically inhibit breast cancer bone metastasis and enhance T-cell targeted therapy	13
Incidence, Risk Factors, and Survival of Bone Metastases and Skeletal-Related Events in Melanoma Patients: A Systematic Review and Quality Assessment of 29 Studies	12
Automatic classification of spinal osteosarcoma and giant cell tumor of bone using optimized DenseNet	12
Targeting ferroptosis in osteosarcoma	12
Preventing osteolytic lesions and osteomyelitis in multiple myeloma	12
What to choose in bone tumour resections? Patient specific instrumentation versus surgical navigation: a systematic review	12
From bimodal to unimodal: The transformed incidence of osteosarcoma in the United States	11
Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma	11
Targeting transforming growth factor beta signaling in metastatic osteosarcoma	11
Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval	11
Surgical management and outcome of Extra-adrenal myelolipomas at unusual locations: A report of 11 cases in a single center	11
External validation of a genitourinary cancer-specific prognostic scoring system to predict survival for patients with bone metastasis (modified B-FOM scoring model): Comparison with other scoring mod	10
Postoperative outcomes of subaxial cervical spine metastasis: Comparison among the anterior, posterior, and combined approaches	10
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	10
Bone tumor examination based on FCNN-4s and CRF fine segmentation fusion algorithm	10
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p	10
Adamantinoma: A review of the current literature	10
Osteoblasts derived from mouse mandible enhance tumor growth of prostate cancer more than osteoblasts derived from long bone	10
Alkaline phosphatase (alp) levels in multiple myeloma and solid cancers with bone lesions: Is there any difference?	10
Erratum to “Identifying biomolecules and constructing a prognostic risk prediction model for recurrence in osteosarcoma” [J. Bone Oncol. 26 (2021) 100331]	9
The role and mechanism of JAK2/STAT3 signaling pathway regulated by m6A methyltransferase KIAA1429 in osteosarcoma	9
Impact of quantitative CT texture analysis on the outcome of CT-guided bone biopsy	9
Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw	9
Sensory nerves: A driver of the vicious cycle in bone metastasis?	9
Is surgery without curettage effective for periacetabular Metastasis? Insights from a survival study of 93 patients	9
Urinary biomarkers in metastatic bone pain: Results from a multicentre randomized trial of ibandronate compared to single dose radiotherapy for localized metastatic bone pain in prostate cancer (RIB)	8
State-of-the-art of minimally invasive treatments of bone metastases	8
N-cadherin in osteolineage cells modulates stromal support of tumor growth	8
Bone niches in the regulation of tumour cell dormancy	8
Radiomics model based on MRI to differentiate spinal multiple myeloma from metastases: A two-center study	8
Therapeutic approaches in patients with bone metastasis due to endometrial carcinoma – A systematic review	8
Phenotypic plasticity – Implications for tumours in bone	8
Silencing of circCYP51A1 represses cell progression and glycolysis by regulating miR-490-3p/KLF12 axis in osteosarcoma under hypoxia	8
Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway	8
Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner	8
Does liquid nitrogen recycled autograft for treatment of bone sarcoma impact local recurrence rate? A systematic review	7
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases	7
Focal adhesion kinase inhibitors prevent osteoblast mineralization in part due to suppression of Akt-mediated stabilization of osterix	7
The patterns of distant metastasis and prognostic factors in patients with primary metastatic Ewing sarcoma of the bone	7
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis	7
LINC00482 sponged miR-2467-3p to promote bone metastasis of prostate cancer through activating Wnt/β-catenin signaling pathway	7
Adjuvant bisphosphonate use in patients with early stage breast cancer: Patient perspectives on treatment acceptability and potential de-escalation	7
Novel_circ_003686 regulates the osteogenic differentiation of MSCs in patients with myeloma bone disease through miR-142-5p/IGF1 axis	7
Adipocytes and metabolism: Contributions to multiple myeloma	7
In vitro three-dimensional cell cultures for bone sarcomas	6
#35. Defining short-form RON mediated anti-tumor immunity in breast cancer bone metastasis	6
#3. IL-17A supports osteoblasts to become cancer-associated fibroblasts in breast cancer bone metastases	6

#10. Investigating the role of non-canonical Hedgehog signaling in paclitaxel-resistant bone- metastatic breast cancer	6
Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction	6
#17. Evolution of epidemiology of bone metastasis in France: A rising issue	6
Prediction of vertebral fractures in cancer patients undergoing hormone deprivation therapies: Reliability of WHO fracture risk assessment tool (FRAX) and bone mineral density in real-life clinical pr	6
Deep bone oncology Diagnostics: Computed tomography based Machine learning for detection of bone tumors from breast cancer metastasis	6
#36. Novel therapeutic development with serine biosynthesis inhibition and molecularly targeted drugs against the aggressive osteosarcoma	6
#5. Activating RET mutations in medullary thyroid cancer cells promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity	6
Contrast-enhanced magnetic resonance image segmentation based on improved U-Net and Inception-ResNet in the diagnosis of spinal metastases	6
Chondroblastoma: Is intralesional curettage with the use of adjuvants a sufficient way of therapy?	5
Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384	5
Prevalence of low bone mineral density and risk of fractures in osteosarcoma and Ewing’s sarcoma survivors: A scoping review	5
Commentary: A Special Edition in bone sarcoma	5
Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer	5
RNA 5-methylcytosine status is associated with DNMT2/TRDMT1 nuclear localization in osteosarcoma cell lines	5
A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results	5
Epidemiology and detection of cement leakage in patients with spine metastases treated with percutaneous vertebroplasty: A 10-year observational study	5
Feasibility outcomes of a randomised, multicentre, pilot trial comparing standard 6-monthly dosing of adjuvant zoledronate with a single one-time dose in patients with early stage breast cancer	5
Non-POEMS osteosclerotic multiple myeloma: Clinical characteristics and differential diagnosis	5
A novel adjunctive diagnostic method for bone cancer: Osteosarcoma cell segmentation based on Twin Swin Transformer with multi-scale feature fusion	5
The role of intraoperative cell salvage for musculoskeletal sarcoma surgery	5
Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature	5
Single-cell RNA-seq reveals intratumoral heterogeneity in osteosarcoma patients: A review	5
Analysis of intercellular communication in the osteosarcoma microenvironment based on single cell sequencing data	5
MUTARS® Humero pro Femur replacement: A novel reconstructive procedure after malignant bone tumor resection of the femur in young children	5
The osteoblast in regulation of tumor cell dormancy and bone metastasis	4
Prosthetic reconstruction following resection of lower extremity bone neoplasms: A systematic review and meta-analysis	4
HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer	4
Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations	4
Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review	4
New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma	4
Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database	4
Separation surgery followed by stereotactic ablative radiotherapy for metastatic epidural spinal cord compression: A systematic review and meta-analysis for local progression rate	4
Neurological outcomes after surgery for spinal metastases in symptomatic patients: Does the type of decompression play a role? A comparison between different strategies in a 10-year experience	4
FBXO22 is a potential therapeutic target for recurrent chondrosarcoma	4
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response	4
Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer	4
Inferior outcome of bone metastasis in non-small-cell-lung-cancer patients treated with epidermal growth factor receptor inhibitors	4
#38. Cholesterol increases bone marrow tumour burden in myeloma in vivo and promotes myeloma cell viability and bortezomib resistance ex vivo	3
#39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis	3
#44. A novel osteolineage-derived (Osterix+) stromal population contributes to breast cancer progression	3
#32. Identification of proteins regulating the metastatic spread of breast cancer to bone: Proteomic analysis of the role of the pro-metastatic transcription factor TWIST1 and the gene target micro-RN	3
Protective effect of bisphosphonate on the cortical bone at key locations of the femur in aromatase inhibitor-associated bone loss: A three-dimensional cortical bone mapping study	3
Real-world patient-reported outcomes of breast cancer or prostate cancer patients receiving antiresorptive therapy for bone metastases: Final results of the PROBone registry study	3
#27. First-in-human evaluation of safety and dosimetry of 64Cu-LLP2A for PET imaging	3
#41. Discovery of novel tubulin code in bone metastasis of breast cancer	3
BoHFAB. The impact of adjuvant zoledronate therapy on bone health in postmenopausal patients with early breast cancer	3
#18. Inhibition of de novo serine synthesis in osteosarcoma depletes cysteine and drives dependency upon exogenous cystine import through system xCT to maintain redox balance	3
All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma	3
Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis	3
Use of paclitaxel carried in lipid core nanoparticles in patients with late-stage solid cancers with bone metastases: Lack of toxicity and therapeutic benefits	3
#19. RANKL independent osteolysis in Adult T cell leukemia via small extracellular vesicles	3
MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway	3
#1. Acid ceramidase (ASAH1) is a key mediator of drug resistance in relapsed/refractory multiple myeloma	3
Effects of abiraterone acetate plus prednisone on bone turnover markers in chemotherapy-naïve mCRPC patients after ADT failure: A prospective analysis of the italian real-world study ABITUDE	3
Preoperative prediction of high-grade osteosarcoma response to neoadjuvant therapy based on a plain CT radiomics model: A dual-center study	3
Adoption of adjuvant bisphosphonates for early breast cancer into standard clinical practice: Challenges and lessons learnt from comparison of the UK and Australian experience	3
#53. Limiting metastatic breast cancer progression by targeting MK2 stromal signaling	3
Cav3.2 T-Type calcium channels downregulation attenuates bone cancer pain induced by inhibiting IGF-1/HIF-1α signaling pathway in the rat spinal cord	2
Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones	2
-AI-assisted diagnostic potential of CT in bone oncology and its impact on clinical decision-making for intensive care	2
Clinical decision-making in bone cancer care management and forecast of ICU needs based on computed tomography	2
Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT	2
Malignancy in giant cell tumor of bone in the extremities	2
Estimating survival and clinical outcome in advanced non-small cell lung cancer with bone-only metastasis using molecular markers	2
AI based diagnostics product design for osteosarcoma cells microscopy imaging of bone cancer patients using CA-MobileNet V3	2
Bone metastases from urothelial carcinoma. The dark side of the moon	2
Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations	2
Bone density measurement in patients with spinal metastatic tumors using chest quantitative CT deep learning model	2
A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors	2
Efficacy of replacing actinomycin-D with carboplatin in Ewing sarcoma consolidation treatment: Single-center experience	2
FGF-23 transmitted tumor – induced hypophosphatemic osteomalacia: A rare case of a young woman with recurrent fractures and review of the literature	2
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway	2
Automated segmentation and source prediction of bone tumors using ConvNeXtv2 Fusion based Mask R-CNN to identify lung cancer metastasis	2
Deep hashing and attention mechanism-based image retrieval of osteosarcoma scans for diagnosis of bone cancer	2
Out with the old (not so!) and in with the new	2
Concurrent capecitabine with external beam radiotherapy versus radiotherapy alone in painful bone metastasis of breast cancer origin	2
Epigenetic control of the vicious cycle	2
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations	1
Trends in primary malignant bone cancer incidence and mortality in the United States, 2000–2017: A population-based study	1
Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28	1

#6. Mechanical loading of breast cancer laden bones alters osteocyte mediated bone loss in vivo	1
#52. Computational modeling of signaling pathways and cell-cell interactions driving tumor-induced bone disease	1
Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma	1
Chemotherapy-induced adipocyte senescence triggers bone loss through RANKL-mediated osteoclastogenesis	1
Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review	1
A randomized trial comparing LY01011, biosimilar candidate, with the reference product denosumab (Xgeva®) in healthy Chinese subjects	1
Implant failure and revision strategies after total spondylectomy for spinal tumors	1
Imaging evaluation of blood supply changes after chemotherapy of osteosarcoma and its correlation with tumor necrosis rate	1
The role of mitochondria-related lncRNAs in characterizing the immune landscape and supervising the prognosis of osteosarcoma	1
Single-cell transcriptional profiling in osteosarcoma and the effect of neoadjuvant chemotherapy on the tumor microenvironment	1
#2. Homing of intestinal NK and Th1 cells to the tumor site restrains melanoma bone growth in a gut microbiome dependent manner	1
#49. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat diet	1
PTHrP biological domains mediate breast cancer bone osteolysis via TGF-β/SNAI2/ZEB1 pathways	1
#20. Investigating the response of prostate cancer cells to bone-derived growth factor gradients via fluid-wall microfluidic culture systems	1
Development and validation of a cuproptosis-related lncRNA model correlated to the cancer-associated fibroblasts enable the prediction prognosis of patients with osteosarcoma	1
DXA assessment and fracture prevention in hormone positive breast cancer patients after treatment initiation with aromatase inhibitors: A registry-based cohort study	1
A fusion of VGG-16 and ViT models for improving bone tumor classification in computed tomography	1
#28. Identification of key proteins within prostate cancer derived exosomes and their role in priming the pre-metastatic niche	1
The role of IL-1B in breast cancer bone metastasis	1
Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways	1
#4. Elucidating the effect of glutamine metabolism in breast-to-bone metastasis	1
#23. Elucidating the role of bone marrow stiffness in estrogen signaling in metastatic breast cancer to the bone	1
#24. Mechanical loading-induced changes to the bone microenvironment control bone metastatic breast cancer lesions	1
#31. A Phase I/II trial of ATI-2231 with Phase Ia in advanced soild tumor malignancies followed by Phase Ib/II in combination with capecitabine in patients with hormone receptor-positive (HR+) and HER	1
Primary perivascular epithelioid cell tumor (PEComa) in bone: A review of the literature and a case arising in the humerus with multiple metastases	1
A global bibliometric and visualized analysis of the status and trends of bone metastasis in breast cancer research from 2002 to 2021	1
#34. The effect of dickkopf-1 (DKK-1) on prostate cancer growth and bone metastasis using the canine osteoblastic Probasco cell line	1