Journal of Bone Oncology

Article	Citations
Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review	53
Separation surgery for metastatic epidural spinal cord compression: A qualitative review	50
Limb-salvage surgery offers better five-year survival rate than amputation in patients with limb osteosarcoma treated with neoadjuvant chemotherapy. A systematic review and meta-analysis	42
New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma	41
Updated guidance on the management of cancer treatment-induced bone loss (CTIBL) in pre- and postmenopausal women with early-stage breast cancer	36
Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways	32
Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval	30
Guidance for the assessment and management of prostate cancer treatment-induced bone loss. A consensus position statement from an expert group	29
Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature	28
Targeting ferroptosis in osteosarcoma	26
Adoptive transfer of TILs plus anti-PD1 therapy: An alternative combination therapy for treating metastatic osteosarcoma	24
Malignancy in giant cell tumor of bone in the extremities	24
The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone	22
Bone cement as a local chemotherapeutic drug delivery carrier in orthopedic oncology: A review	19
LncRNA SNHG16 promotes epithelial-mesenchymal transition by upregulating ITGA6 through miR-488 inhibition in osteosarcoma	18
Neurological outcomes after surgery for spinal metastases in symptomatic patients: Does the type of decompression play a role? A comparison between different strategies in a 10-year experience	18
Oestrogen and zoledronic acid driven changes to the bone and immune environments: Potential mechanisms underlying the differential anti-tumour effects of zoledronic acid in pre- and post-menopausal co	18
Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384	18
Osteoporosis management in hematologic stem cell transplant recipients: Executive summary	18
Role of microRNAs in the crosstalk between osteosarcoma cells and the tumour microenvironment	18
One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma	17
Primary bone lymphoma: Clinical presentation and therapeutic considerations	17
Prediction of the early recurrence in spinal giant cell tumor of bone using radiomics of preoperative CT: Long-term outcome of 62 consecutive patients	17
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties	16
Sensory nerves: A driver of the vicious cycle in bone metastasis?	16

In vitro three-dimensional cell cultures for bone sarcomas	15
Giant cell tumor of bone: A single center study of 115 cases	15
Alkaline phosphatase (alp) levels in multiple myeloma and solid cancers with bone lesions: Is there any difference?	15
MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway	15
All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma	14
Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas	14
Development and validation of a cuproptosis-related lncRNA model correlated to the cancer-associated fibroblasts enable the prediction prognosis of patients with osteosarcoma	14
Real-world practice patterns and attitudes towards de-escalation of bone-modifying agents in patients with bone metastases from breast and prostate cancer: A physician survey	13
Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer	13
Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial	13
Surgical outcomes of metastatic bone tumors in the extremities (Surgical outcomes of bone metastases)	13
c-Met expression in renal cell carcinoma with bone metastases	13
Potential diagnostic value of circulating miRNA for multiple myeloma: A meta-analysis	12
Prediction of vertebral fractures in cancer patients undergoing hormone deprivation therapies: Reliability of WHO fracture risk assessment tool (FRAX) and bone mineral density in real-life clinical pr	12
Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices	12
External validation of a genitourinary cancer-specific prognostic scoring system to predict survival for patients with bone metastasis (modified B-FOM scoring model): Comparison with other scoring mod	12
ELF1-activated FOXD3-AS1 promotes the migration, invasion and EMT of osteosarcoma cells via sponging miR-296-5p to upregulate ZCCHC3	12
Chondroblastoma: Is intralesional curettage with the use of adjuvants a sufficient way of therapy?	12
Primary perivascular epithelioid cell tumor (PEComa) in bone: A review of the literature and a case arising in the humerus with multiple metastases	11
Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations	11
Delay in diagnosis of primary osteosarcoma of bone in children: Have we improved in the last 15 years and what is the impact of delay on diagnosis?	11
CircRERE confers the resistance of multiple myeloma to bortezomib depending on the regulation of CD47 by exerting the sponge effect on miR-152-3p	10
Identifying biomolecules and constructing a prognostic risk prediction model for recurrence in osteosarcoma	10
Epidemiology and detection of cement leakage in patients with spine metastases treated with percutaneous vertebroplasty: A 10-year observational study	10
Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis	10
m6A-dependent upregulation of TRAF6 by METTL3 is associated with metastatic osteosarcoma	10
Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression	10
von Willebrand factor promotes platelet-induced metastasis of osteosarcoma through activation of the VWF-GPIb axis	10
Risk factors associated with skeletal-related events following discontinuation of denosumab treatment among patients with bone metastases from solid tumors: A real-world machine learning approach	10
Bone metastases from urothelial carcinoma. The dark side of the moon	10
The patterns of distant metastasis and prognostic factors in patients with primary metastatic Ewing sarcoma of the bone	9
Management of bone metastasis with zoledronic acid: A systematic review and Bayesian network meta-analysis	9
Long non-coding RNA BLACAT1 expedites osteosarcoma cell proliferation, migration and invasion via up-regulating SOX12 through miR-608	9
Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma	9
Desmoplastic fibroma of the jaw bones: A series of twenty-two cases	9
Chemotherapy in the management of periosteal osteosarcoma: A narrative review	9
A predictive biomarker panel for bone metastases: Liquid biopsy approach	9
Long-non-coding RNA RUSC1-AS1 accelerates osteosarcoma development by miR-101-3p-mediated Notch1 signalling pathway	8
Down-regulation of circular RNA hsa_circ_0007534 suppresses cell growth by regulating miR-219a-5p/SOX5 axis in osteosarcoma	8
Evaluation of local and circulating osteopontin in malignant and benign primary bone tumors	8
HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer	8
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target	8
Does vitamin D deficiency predict tumour malignancy in patients with bone tumours? Data from a multi-center cohort analysis	8
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway	8
The role of intraoperative cell salvage for musculoskeletal sarcoma surgery	8
Two-year results of a randomised trial comparing 4- versus 12-weekly bone-targeted agent use in patients with bone metastases from breast or castration-resistant prostate cancer	8
Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma	8
Lipopolysaccharide-binding protein expression is associated to the metastatic status of osteosarcoma patients	8
Pre-operative prognostic nutritional index was associated with recurrence after surgery in giant cell tumor of bone patients	8
Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy – Observational prospective single institution analysis	8

Application of “omics” sciences to the prediction of bone metastases from breast cancer: State of the art	7
Outcomes and prognostic factors after surgery for bone metastases in the extremities and pelvis: A retrospective analysis of 140 patients	7
Inferior outcome of bone metastasis in non-small-cell-lung-cancer patients treated with epidermal growth factor receptor inhibitors	7
Quality of resection margin with patient specific instrument for bone tumor resection	7
Comprehensive multi-omics analysis reveals m7G-related signature for evaluating prognosis and immunotherapy efficacy in osteosarcoma	7
Deep learning-based magnetic resonance imaging of the spine in the diagnosis and physiological evaluation of spinal metastases	7
EFEMP1 binds to STEAP1 to promote osteosarcoma proliferation and invasion via the Wnt/β-catenin and TGF-β/Smad2/3 signal pathways	7
Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis	7
Adoption of adjuvant bisphosphonates for early breast cancer into standard clinical practice: Challenges and lessons learnt from comparison of the UK and Australian experience	6
Feasibility outcomes of a randomised, multicentre, pilot trial comparing standard 6-monthly dosing of adjuvant zoledronate with a single one-time dose in patients with early stage breast cancer	6
Suicide and accidental deaths among patients with primary malignant bone tumors	6
Indirect bilirubin impairs invasion of osteosarcoma cells via inhibiting the PI3K/AKT/MMP-2 signaling pathway by suppressing intracellular ROS	6
Single-cell RNA-seq reveals intratumoral heterogeneity in osteosarcoma patients: A review	6
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases	6
High prevalence of vertebral fractures at initiation of androgen deprivation therapy for prostate cancer	6
Real-world patient-reported outcomes of breast cancer or prostate cancer patients receiving antiresorptive therapy for bone metastases: Final results of the PROBone registry study	6
A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results	6
Impact of whole-body vibration exercise on physical performance and bone turnover in patients with monoclonal gammopathy of undetermined significance	6
Preoperative CT for prediction of local recurrence after curettage of giant cell tumor of bone	6
Natural history of stage II/III breast cancer, bone metastasis and the impact of adjuvant zoledronate on distribution of recurrences	5
Analysis of morbidity and mortality in patients with primary bone tumors who underwent sacrectomy: A systematic review	5
RCAN1.4 suppresses the osteosarcoma growth and metastasis via interfering with the calcineurin/NFAT signaling pathway	5
Adjuvant bisphosphonate use in patients with early stage breast cancer: Patient perspectives on treatment acceptability and potential de-escalation	5
Osteoblasts derived from mouse mandible enhance tumor growth of prostate cancer more than osteoblasts derived from long bone	5
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells	5
Large-Scale assessment of ChatGPT's performance in benign and malignant bone tumors imaging report diagnosis and its potential for clinical applications	5
The perplexing role of immuno-oncology drugs in osteosarcoma	5
Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database	5
Silencing of circCYP51A1 represses cell progression and glycolysis by regulating miR-490-3p/KLF12 axis in osteosarcoma under hypoxia	5
Surgical management and outcome of Extra-adrenal myelolipomas at unusual locations: A report of 11 cases in a single center	5
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	5
Extra-articular resection of the hip joint for pelvic sarcomas: Are there any oncological and functional risks compared with intra-articular resection?	5
Immune checkpoint inhibitors in bone metastasis: Clinical challenges, toxicities, and mechanisms	5
The 100 most cited papers on bone metastasis: A bibliometric analysis	5
The role and mechanism of JAK2/STAT3 signaling pathway regulated by m6A methyltransferase KIAA1429 in osteosarcoma	5
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p	5
What to choose in bone tumour resections? Patient specific instrumentation versus surgical navigation: a systematic review	5
Prognostic factors and survival of patients undergoing surgical intervention for breast cancer bone metastases	5
Concurrent capecitabine with external beam radiotherapy versus radiotherapy alone in painful bone metastasis of breast cancer origin	4
Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review	4
Preventing osteolytic lesions and osteomyelitis in multiple myeloma	4
Isoquercitrin restrains the proliferation and promotes apoptosis of human osteosarcoma cells by inhibiting the Wnt/β-catenin pathway	4
Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma	4
Separation surgery followed by stereotactic ablative radiotherapy for metastatic epidural spinal cord compression: A systematic review and meta-analysis for local progression rate	4
Study of imaging changes following preoperative denosumab for giant cell tumor of bone	4
Molecular and biologic biomarkers of Ewing sarcoma: A systematic review	4
Joint-sparing reconstruction for extensive periacetabular metastases: Literature review and a novel minimally invasive surgical technique	4
A global bibliometric and visualized analysis of the status and trends of bone metastasis in breast cancer research from 2002 to 2021	4
State-of-the-art of minimally invasive treatments of bone metastases	4
Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling	4
Genetic characterization of a novel organoid from human malignant giant-cell tumor	3
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations	3
A fusion of VGG-16 and ViT models for improving bone tumor classification in computed tomography	3
Effects of abiraterone acetate plus prednisone on bone turnover markers in chemotherapy-naïve mCRPC patients after ADT failure: A prospective analysis of the italian real-world study ABITUDE	3
Analysis of intercellular communication in the osteosarcoma microenvironment based on single cell sequencing data	3
LINC00482 sponged miR-2467-3p to promote bone metastasis of prostate cancer through activating Wnt/β-catenin signaling pathway	3
Impact of adjuvant imatinib on bone and muscle density in patients with resected gastrointestinal stromal tumors	3
Circular RNA circDOCK1 contributes to osteosarcoma progression by acting as a ceRNA for miR-936 to regulate LEF1	3
Clinical and dosimetric risk factors for vertebral compression fracture after single-fraction stereotactic body radiation therapy for spine metastases	3
FGF-23 transmitted tumor – induced hypophosphatemic osteomalacia: A rare case of a young woman with recurrent fractures and review of the literature	3
Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations	3
Prosthetic reconstruction following resection of lower extremity bone neoplasms: A systematic review and meta-analysis	3
Contrast-enhanced magnetic resonance image segmentation based on improved U-Net and Inception-ResNet in the diagnosis of spinal metastases	3
Adamantinoma: A review of the current literature	3
Tyrosine kinase inhibitors in osteosarcoma: Adapting treatment strategiesa	3
Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas	3
Estimating survival and clinical outcome in advanced non-small cell lung cancer with bone-only metastasis using molecular markers	3
Use of paclitaxel carried in lipid core nanoparticles in patients with late-stage solid cancers with bone metastases: Lack of toxicity and therapeutic benefits	3
RNA 5-methylcytosine status is associated with DNMT2/TRDMT1 nuclear localization in osteosarcoma cell lines	3
Focal adhesion kinase inhibitors prevent osteoblast mineralization in part due to suppression of Akt-mediated stabilization of osterix	3
Prosthesis or osteosynthesis for the treatment of a pathological hip fracture? A nationwide registry-based cohort study	3
The role of mitochondria-related lncRNAs in characterizing the immune landscape and supervising the prognosis of osteosarcoma	2
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis	2
Targeting transforming growth factor beta signaling in metastatic osteosarcoma	2
Quantitative preoperative patient assessments are related to survival and procedure outcome for osseous metastases	2
How has the field of metastatic breast cancer in bones evolved over the past 22 years?	2
Pelvic bone tumor segmentation fusion algorithm based on fully convolutional neural network and conditional random field	2
Bone sarcoma follow-up; a nationwide analysis of oncological events after initial treatment	2
Efficacy of replacing actinomycin-D with carboplatin in Ewing sarcoma consolidation treatment: Single-center experience	2
Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway	2

CD44 expression is correlated with osteosarcoma cell progression and immune infiltration and affects the Wnt/β-catenin signaling pathway	2
Epithelial-mesenchymal transition related to bone invasion in oral squamous cell carcinoma	2
A quantitative CT analysis of fibula inlayed in a massive allograft for femoral diaphysis reconstruction	2
Surgical margin assessment of bone tumours: A systematic review of current and emerging technologies	2
Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28	2
Innovation in proximal femoral replacement for oncology patients—A novel eggshell procedure	2
Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner	2
Multicenter study on atypical femoral fractures in patients with bone metastases taking bone- modifying agents	2
Long non-coding RNA PVT1 (PVT1) affects the expression of CCND1 and promotes doxorubicin resistance in osteosarcoma cells	2
TIAM2 promotes proliferation and invasion of osteosarcoma cells by activating the JAK2/STAT3 signaling pathway	2
Intramedullary rod failure in metastatic breast cancer: Do triple negative cancer patients have more revision surgery?	2