OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Bone Oncology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Bone metastases in thyroid cancer	51
Separation surgery for metastatic epidural spinal cord compression: A qualitative review	39
Prognostic factors in osteosarcoma: A study level meta-analysis and systematic review of current practice	37
Limb-salvage surgery offers better five-year survival rate than amputation in patients with limb osteosarcoma treated with neoadjuvant chemotherapy. A systematic review and meta-analysis	36
New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma	36
Exosomes derived from bone marrow mesenchymal stem cells promote osteosarcoma development by activating oncogenic autophagy	35
Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review	33
Updated guidance on the management of cancer treatment-induced bone loss (CTIBL) in pre- and postmenopausal women with early-stage breast cancer	27
Guidance for the assessment and management of prostate cancer treatment-induced bone loss. A consensus position statement from an expert group	24
Targeting ferroptosis in osteosarcoma	24
Potential diagnostic value of miRNAs in peripheral blood for osteosarcoma: A meta-analysis	22
Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways	22
Malignancy in giant cell tumor of bone in the extremities	21
Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature	21
The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone	20
The local and circulating SOX9 as a potential biomarker for the diagnosis of primary bone cancer	20
Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval	20
Adoptive transfer of TILs plus anti-PD1 therapy: An alternative combination therapy for treating metastatic osteosarcoma	18
Neurological outcomes after surgery for spinal metastases in symptomatic patients: Does the type of decompression play a role? A comparison between different strategies in a 10-year experience	17
Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384	17
Role of microRNAs in the crosstalk between osteosarcoma cells and the tumour microenvironment	16
LncRNA SNHG16 promotes epithelial-mesenchymal transition by upregulating ITGA6 through miR-488 inhibition in osteosarcoma	16
Oestrogen and zoledronic acid driven changes to the bone and immune environments: Potential mechanisms underlying the differential anti-tumour effects of zoledronic acid in pre- and post-menopausal co	16
Bone cement as a local chemotherapeutic drug delivery carrier in orthopedic oncology: A review	16
ceRNA network development and tumour-infiltrating immune cell analysis of metastatic breast cancer to bone	16

Sensory nerves: A driver of the vicious cycle in bone metastasis?	15
Adapting palliative radiation therapy for bone metastases during the Covid-19 pandemic: GEMO position paper	15
The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties	14
Osteoporosis management in hematologic stem cell transplant recipients: Executive summary	14
The inhibition of MARK2 suppresses cisplatin resistance of osteosarcoma stem cells by regulating DNA damage and repair	14
Prediction of the early recurrence in spinal giant cell tumor of bone using radiomics of preoperative CT: Long-term outcome of 62 consecutive patients	14
Periacetabular reconstruction following limb-salvage surgery for pelvic sarcomas	13
MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway	12
In vitro three-dimensional cell cultures for bone sarcomas	12
Giant cell tumor of bone: A single center study of 115 cases	12
Potential diagnostic value of circulating miRNA for multiple myeloma: A meta-analysis	11
One oncogene, several vulnerabilities: EWS/FLI targeted therapies for Ewing sarcoma	11
Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer	11
Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin	11
ELF1-activated FOXD3-AS1 promotes the migration, invasion and EMT of osteosarcoma cells via sponging miR-296-5p to upregulate ZCCHC3	10
All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma	10
Prediction of vertebral fractures in cancer patients undergoing hormone deprivation therapies: Reliability of WHO fracture risk assessment tool (FRAX) and bone mineral density in real-life clinical pr	10
Real-world practice patterns and attitudes towards de-escalation of bone-modifying agents in patients with bone metastases from breast and prostate cancer: A physician survey	10
Development and validation of a cuproptosis-related lncRNA model correlated to the cancer-associated fibroblasts enable the prediction prognosis of patients with osteosarcoma	10
c-Met expression in renal cell carcinoma with bone metastases	10
Surgical outcomes of metastatic bone tumors in the extremities (Surgical outcomes of bone metastases)	10
Clarifying prognostic factors of small cell osteosarcoma: A pooled analysis of 20 cases and the literature	10
Primary bone lymphoma: Clinical presentation and therapeutic considerations	10
Patterns of care for patients with metastatic bone disease in solid tumors: A cross-sectional study from Switzerland (SAKK 95/16)	9
von Willebrand factor promotes platelet-induced metastasis of osteosarcoma through activation of the VWF-GPIb axis	9
Primary perivascular epithelioid cell tumor (PEComa) in bone: A review of the literature and a case arising in the humerus with multiple metastases	9
Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations	9
Alkaline phosphatase (alp) levels in multiple myeloma and solid cancers with bone lesions: Is there any difference?	9
Heterogeneity of chondrosarcomas response to irradiations with X-rays and carbon ions: A comparative study on five cell lines	9
Identifying biomolecules and constructing a prognostic risk prediction model for recurrence in osteosarcoma	9
Clinical course of grafted cartilage in osteoarticular frozen autografts for reconstruction after resection of malignant bone and soft-tissue tumor involving an epiphysis	9
Chondroblastoma: Is intralesional curettage with the use of adjuvants a sufficient way of therapy?	9
Delay in diagnosis of primary osteosarcoma of bone in children: Have we improved in the last 15 years and what is the impact of delay on diagnosis?	9
Denosumab versus zoledronic acid in cases of surgically unsalvageable giant cell tumor of bone: A randomized clinical trial	9
Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices	9
Epidemiology and detection of cement leakage in patients with spine metastases treated with percutaneous vertebroplasty: A 10-year observational study	9
A predictive biomarker panel for bone metastases: Liquid biopsy approach	8
Lipopolysaccharide-binding protein expression is associated to the metastatic status of osteosarcoma patients	8
m6A-dependent upregulation of TRAF6 by METTL3 is associated with metastatic osteosarcoma	8
External validation of a genitourinary cancer-specific prognostic scoring system to predict survival for patients with bone metastasis (modified B-FOM scoring model): Comparison with other scoring mod	8
CircRERE confers the resistance of multiple myeloma to bortezomib depending on the regulation of CD47 by exerting the sponge effect on miR-152-3p	8
Bone decalcification to assess programmed cell death ligand 1 expression in bone metastases of non-small cell lung cancers	8
Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy – Observational prospective single institution analysis	8
Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma	8
Identification of GPC3 mutation and upregulation in a multidrug resistant osteosarcoma and its spheroids as therapeutic target	8
Long non-coding RNA BLACAT1 expedites osteosarcoma cell proliferation, migration and invasion via up-regulating SOX12 through miR-608	8
Rapid detection of EGFR mutations in decalcified lung cancer bone metastasis	8
Incidence of atypical femoral fractures in the treatment of bone metastasis: An alert report	8
Long-non-coding RNA RUSC1-AS1 accelerates osteosarcoma development by miR-101-3p-mediated Notch1 signalling pathway	7
Chemotherapy in the management of periosteal osteosarcoma: A narrative review	7

Bone metastases from urothelial carcinoma. The dark side of the moon	7
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway	7
Effects of different levels of TGF-β expression and tumor cell necrosis rates in osteosarcoma on the chemotherapy resistance of osteosarcoma	7
Long noncoding RNA OR3A4 promotes the proliferation and invasion of osteosarcoma cells by sponging miR-1227-5p	7
Optimization of a syngeneic murine model of bone metastasis	7
Pre-operative prognostic nutritional index was associated with recurrence after surgery in giant cell tumor of bone patients	7
The patterns of distant metastasis and prognostic factors in patients with primary metastatic Ewing sarcoma of the bone	7
Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression	7
Risk factors associated with skeletal-related events following discontinuation of denosumab treatment among patients with bone metastases from solid tumors: A real-world machine learning approach	7
Autocrine motility factor and its receptor expression in musculoskeletal tumors	7
Differential diagnostic value of 18F-FDG PET/CT in osteolytic lesions	7
The minimally invasive endoscopic technique for the treatment of symptomatic benign bone lesions: Preliminary results from a retrospective study	7
Desmoplastic fibroma of the jaw bones: A series of twenty-two cases	6
Down-regulation of circular RNA hsa_circ_0007534 suppresses cell growth by regulating miR-219a-5p/SOX5 axis in osteosarcoma	6
Evaluation of local and circulating osteopontin in malignant and benign primary bone tumors	6
Real-world patient-reported outcomes of breast cancer or prostate cancer patients receiving antiresorptive therapy for bone metastases: Final results of the PROBone registry study	6
Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis	6
Application of “omics” sciences to the prediction of bone metastases from breast cancer: State of the art	6
Preoperative CT for prediction of local recurrence after curettage of giant cell tumor of bone	6
Influence of chemotherapy and endocrine treatment on fractures in postmenopausal women with breast cancer – a retrospective cohort study	6
HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer	6
EFEMP1 binds to STEAP1 to promote osteosarcoma proliferation and invasion via the Wnt/β-catenin and TGF-β/Smad2/3 signal pathways	6
Two-year results of a randomised trial comparing 4- versus 12-weekly bone-targeted agent use in patients with bone metastases from breast or castration-resistant prostate cancer	6
The role of intraoperative cell salvage for musculoskeletal sarcoma surgery	6
Does vitamin D deficiency predict tumour malignancy in patients with bone tumours? Data from a multi-center cohort analysis	6
Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis	6
High-Grade Surface Osteosarcoma: Clinical Features and Oncologic Outcome	5
Adoption of adjuvant bisphosphonates for early breast cancer into standard clinical practice: Challenges and lessons learnt from comparison of the UK and Australian experience	5
A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results	5
Quality of resection margin with patient specific instrument for bone tumor resection	5
Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma	5
Inferior outcome of bone metastasis in non-small-cell-lung-cancer patients treated with epidermal growth factor receptor inhibitors	5
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases	5
Suicide and accidental deaths among patients with primary malignant bone tumors	5
Outcomes and prognostic factors after surgery for bone metastases in the extremities and pelvis: A retrospective analysis of 140 patients	5
Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database	5
Impact of whole-body vibration exercise on physical performance and bone turnover in patients with monoclonal gammopathy of undetermined significance	5
Isoquercitrin restrains the proliferation and promotes apoptosis of human osteosarcoma cells by inhibiting the Wnt/β-catenin pathway	4
The perplexing role of immuno-oncology drugs in osteosarcoma	4
The role and mechanism of JAK2/STAT3 signaling pathway regulated by m6A methyltransferase KIAA1429 in osteosarcoma	4
Prognostic factors and survival of patients undergoing surgical intervention for breast cancer bone metastases	4
Preventing osteolytic lesions and osteomyelitis in multiple myeloma	4
Extra-articular resection of the hip joint for pelvic sarcomas: Are there any oncological and functional risks compared with intra-articular resection?	4
Natural history of stage II/III breast cancer, bone metastasis and the impact of adjuvant zoledronate on distribution of recurrences	4
Comprehensive multi-omics analysis reveals m7G-related signature for evaluating prognosis and immunotherapy efficacy in osteosarcoma	4
Adjuvant bisphosphonate use in patients with early stage breast cancer: Patient perspectives on treatment acceptability and potential de-escalation	4
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells	4
Clinical features and prognosis analysis of metastatic spinal pheochromocytoma: A single center retrospective study	4
Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling	4
Allogenic γδ T cell and tumor cell fused vaccine for enhanced immunotherapeutic efficacy of osteosarcoma	4
Feasibility outcomes of a randomised, multicentre, pilot trial comparing standard 6-monthly dosing of adjuvant zoledronate with a single one-time dose in patients with early stage breast cancer	4
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	4