Journal of Bone Oncology

Article	Citations
Using β-Elemene to reduce stemness and drug resistance in osteosarcoma: A focus on the AKT/FOXO1 signaling pathway and immune modulation	86
Fracture risk in breast cancer: Does obesity have an effect? A scoping review	48
Role of the osteocyte in bone metastasis – The importance of networking	44
Senescence in the bone marrow microenvironment: A driver in development of therapy-related myeloid neoplasms	41
Impact of adjuvant imatinib on bone and muscle density in patients with resected gastrointestinal stromal tumors	35
Is surgery without curettage effective for periacetabular Metastasis? Insights from a survival study of 93 patients	32
Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy – Observational prospective single institution analysis	30
YBX1-interacting small RNAs and RUNX2 can be blocked in primary bone cancer using CADD522	24
Automated measurement of lumbar pedicle screw parameters using deep learning algorithm on preoperative CT scans	20
Study of imaging changes following preoperative denosumab for giant cell tumor of bone	20
#37. Lactate-GPR81 signaling in acute myeloid leukemia (AML) contributes to bone marrow microenvironment dysfunction, macrophage polarization, and leukemia cell growth	19
#43. Long-chain acyl-CoA synthetases support multiple myeloma cell proliferation, survival and mitochondrial function	19
#9. Inhibition of the fatty acid binding proteins (FABPs) in myeloma cells modifies their lipid composition	19
#45. Fatty acid binding proteins may modulate myeloma in Fabp4/5 double knockout mouse	19
#21. PD-1 blockade induces bone loss and reduces bone strength in a breast cancer bone metastasis model	19
#15. Single-cell discovery and multi-omic characterization of therapeutic targets in multiple myeloma	17
#42. Local and systemic effects of Dickkopf-1 during breast cancer progression by limiting NK cell-mediated killing	17
CDK4/6 inhibitor and doxorubicin synergistically inhibit breast cancer bone metastasis and enhance T-cell targeted therapy	17
#33. PTHrP biological domains differentially regulate breast tumor intracrine signaling independent of nuclear localization	17
Preventing osteolytic lesions and osteomyelitis in multiple myeloma	16
#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer	16
What to choose in bone tumour resections? Patient specific instrumentation versus surgical navigation: a systematic review	15
Lipid metabolic reprogramming and associated ferroptosis in osteosarcoma: From molecular mechanisms to potential targets	15
Molecular pathological insights into tumorigenesis and progression of giant cell tumor of bone	14
Prognostic factors and survival of patients undergoing surgical intervention for breast cancer bone metastases	13

Incidence, Risk Factors, and Survival of Bone Metastases and Skeletal-Related Events in Melanoma Patients: A Systematic Review and Quality Assessment of 29 Studies	13
Long non-coding RNA KRT8P41/miR-193a-3p/FUBP1 axis modulates the proliferation and invasion of chordoma cells	13
Automatic classification of spinal osteosarcoma and giant cell tumor of bone using optimized DenseNet	13
Prosthesis or osteosynthesis for the treatment of a pathological hip fracture? A nationwide registry-based cohort study	13
Hsa_circ_0010220 regulates miR-198/Syntaxin 6 axis to promote osteosarcoma progression	12
Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma	12
Surgical management and outcome of Extra-adrenal myelolipomas at unusual locations: A report of 11 cases in a single center	12
Deep learning-based magnetic resonance imaging of the spine in the diagnosis and physiological evaluation of spinal metastases	11
Macrophage heterogeneity in bone metastasis	11
Bones and guts – Why the microbiome matters	11
From bimodal to unimodal: The transformed incidence of osteosarcoma in the United States	10
Postoperative outcomes of subaxial cervical spine metastasis: Comparison among the anterior, posterior, and combined approaches	10
Emerging roles for stromal cells in bone metastasis	10
Experience with denosumab (XGEVA®) for prevention of skeletal-related events in the 10 years after approval	10
Bone tumor examination based on FCNN-4s and CRF fine segmentation fusion algorithm	10
Targeting ferroptosis in osteosarcoma	9
Targeting transforming growth factor beta signaling in metastatic osteosarcoma	9
Langerhans Cell Histiocytosis: A Population-based Study of Anatomical Distribution and Treatment Patterns	9
Epidemiology and detection of cement leakage in patients with spine metastases treated with percutaneous vertebroplasty: A 10-year observational study	9
Erratum to “Identifying biomolecules and constructing a prognostic risk prediction model for recurrence in osteosarcoma” [J. Bone Oncol. 26 (2021) 100331]	9
MAT2A inhibits the ferroptosis in osteosarcoma progression regulated by miR-26b-5p	9
Sensory nerves: A driver of the vicious cycle in bone metastasis?	9
Chinese expert consensus on the diagnosis and clinical management of medication-related osteonecrosis of the jaw	9
Adamantinoma: A review of the current literature	9
The impact of androgen deprivation therapy on bone microarchitecture in men with prostate cancer: A longitudinal observational study (The ANTELOPE Study)	9
Radiomics model based on MRI to differentiate spinal multiple myeloma from metastases: A two-center study	8
Establishment and characterization of a highly metastatic human osteosarcoma cell line from osteosarcoma lung metastases	8
N-cadherin in osteolineage cells modulates stromal support of tumor growth	8
Adipocytes and metabolism: Contributions to multiple myeloma	8
Impact of quantitative CT texture analysis on the outcome of CT-guided bone biopsy	8
Luteolin attenuates the chemoresistance of osteosarcoma through inhibiting the PTN/β-catenin/MDR1 signaling axis by upregulating miR-384	8
Focal adhesion kinase inhibitors prevent osteoblast mineralization in part due to suppression of Akt-mediated stabilization of osterix	8
Bone niches in the regulation of tumour cell dormancy	8
Novel_circ_003686 regulates the osteogenic differentiation of MSCs in patients with myeloma bone disease through miR-142-5p/IGF1 axis	8
Pexmetinib suppresses osteoclast formation and breast cancer induced osteolysis via P38/STAT3 signal pathway	8
Phenotypic plasticity – Implications for tumours in bone	8
Urinary biomarkers in metastatic bone pain: Results from a multicentre randomized trial of ibandronate compared to single dose radiotherapy for localized metastatic bone pain in prostate cancer (RIB)	7
Therapeutic approaches in patients with bone metastasis due to endometrial carcinoma – A systematic review	7
A novel adjunctive diagnostic method for bone cancer: Osteosarcoma cell segmentation based on Twin Swin Transformer with multi-scale feature fusion	7
Does liquid nitrogen recycled autograft for treatment of bone sarcoma impact local recurrence rate? A systematic review	7
#36. Novel therapeutic development with serine biosynthesis inhibition and molecularly targeted drugs against the aggressive osteosarcoma	7
The role and mechanism of JAK2/STAT3 signaling pathway regulated by m6A methyltransferase KIAA1429 in osteosarcoma	7
Use of FVB Myc-CaP cells as an immune competent, androgen receptor positive, mouse model of prostate cancer bone metastasis	7
State-of-the-art of minimally invasive treatments of bone metastases	7
Deep bone oncology Diagnostics: Computed tomography based Machine learning for detection of bone tumors from breast cancer metastasis	7
#35. Defining short-form RON mediated anti-tumor immunity in breast cancer bone metastasis	7
Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner	7
Comparative analysis of aggressiveness in giant cell tumor of bone between upper and lower extremities: A systematic review and meta-analysis	7
Adjuvant bisphosphonate use in patients with early stage breast cancer: Patient perspectives on treatment acceptability and potential de-escalation	7
Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction	7

The patterns of distant metastasis and prognostic factors in patients with primary metastatic Ewing sarcoma of the bone	7
#3. IL-17A supports osteoblasts to become cancer-associated fibroblasts in breast cancer bone metastases	6
Prevalence of low bone mineral density and risk of fractures in osteosarcoma and Ewing’s sarcoma survivors: A scoping review	6
LINC00482 sponged miR-2467-3p to promote bone metastasis of prostate cancer through activating Wnt/β-catenin signaling pathway	6
#10. Investigating the role of non-canonical Hedgehog signaling in paclitaxel-resistant bone- metastatic breast cancer	6
Contrast-enhanced magnetic resonance image segmentation based on improved U-Net and Inception-ResNet in the diagnosis of spinal metastases	6
In vitro three-dimensional cell cultures for bone sarcomas	6
Current strategies for the treatment of solitary and aneurysmal bone cysts: A review of the literature	6
#5. Activating RET mutations in medullary thyroid cancer cells promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity	6
A phase IB and randomised phase IIA trial of CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases: CARBON trial results	6
Silencing of circCYP51A1 represses cell progression and glycolysis by regulating miR-490-3p/KLF12 axis in osteosarcoma under hypoxia	6
The role of intraoperative cell salvage for musculoskeletal sarcoma surgery	6
#17. Evolution of epidemiology of bone metastasis in France: A rising issue	6
Prediction of vertebral fractures in cancer patients undergoing hormone deprivation therapies: Reliability of WHO fracture risk assessment tool (FRAX) and bone mineral density in real-life clinical pr	5
Association of androgen receptor and tumour-infiltrating lymphocytes with bone recurrence in triple-negative breast cancer	5
RNA 5-methylcytosine status is associated with DNMT2/TRDMT1 nuclear localization in osteosarcoma cell lines	5
Single-cell RNA-seq reveals intratumoral heterogeneity in osteosarcoma patients: A review	5
Commentary: A Special Edition in bone sarcoma	5
Comprehensive landscape of TGFβ-related signature in osteosarcoma for predicting prognosis, immune characteristics, and therapeutic response	5
Targeting the IGF/PI3K/mTOR pathway and AXL/YAP1/TAZ pathways in primary bone cancer	5
Non-POEMS osteosclerotic multiple myeloma: Clinical characteristics and differential diagnosis	5
MUTARS® Humero pro Femur replacement: A novel reconstructive procedure after malignant bone tumor resection of the femur in young children	5
#44. A novel osteolineage-derived (Osterix+) stromal population contributes to breast cancer progression	4
BoHFAB. The impact of adjuvant zoledronate therapy on bone health in postmenopausal patients with early breast cancer	4
#18. Inhibition of de novo serine synthesis in osteosarcoma depletes cysteine and drives dependency upon exogenous cystine import through system xCT to maintain redox balance	4
Preoperative prediction of high-grade osteosarcoma response to neoadjuvant therapy based on a plain CT radiomics model: A dual-center study	4
Separation surgery followed by stereotactic ablative radiotherapy for metastatic epidural spinal cord compression: A systematic review and meta-analysis for local progression rate	4
Frequency and reason for reoperation following non-invasive expandable endoprostheses: A systematic review	4
#41. Discovery of novel tubulin code in bone metastasis of breast cancer	4
#27. First-in-human evaluation of safety and dosimetry of 64Cu-LLP2A for PET imaging	4
#53. Limiting metastatic breast cancer progression by targeting MK2 stromal signaling	4
Protective effect of bisphosphonate on the cortical bone at key locations of the femur in aromatase inhibitor-associated bone loss: A three-dimensional cortical bone mapping study	4
Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations	4
#39. Bone-derived Dickkopf-related protein 1 supports primary breast cancer growth and alters hematopoiesis	4
#38. Cholesterol increases bone marrow tumour burden in myeloma in vivo and promotes myeloma cell viability and bortezomib resistance ex vivo	4
#1. Acid ceramidase (ASAH1) is a key mediator of drug resistance in relapsed/refractory multiple myeloma	4
#32. Identification of proteins regulating the metastatic spread of breast cancer to bone: Proteomic analysis of the role of the pro-metastatic transcription factor TWIST1 and the gene target micro-RN	4
#19. RANKL independent osteolysis in Adult T cell leukemia via small extracellular vesicles	4
Inferior outcome of bone metastasis in non-small-cell-lung-cancer patients treated with epidermal growth factor receptor inhibitors	4
Circular RNA circANKIB1 promotes the progression of osteosarcoma by regulating miR-217/PAX3 axis	3
MiR-451a promotes cell growth, migration and EMT in osteosarcoma by regulating YTHDC1-mediated m6A methylation to activate the AKT/mTOR signaling pathway	3
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway	3
A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors	3
Bone density measurement in patients with spinal metastatic tumors using chest quantitative CT deep learning model	3
Real-world patient-reported outcomes of breast cancer or prostate cancer patients receiving antiresorptive therapy for bone metastases: Final results of the PROBone registry study	3
Cav3.2 T-Type calcium channels downregulation attenuates bone cancer pain induced by inhibiting IGF-1/HIF-1α signaling pathway in the rat spinal cord	3
Faster R-CNN model for target recognition and diagnosis of scapular fractures	3
Clinical decision-making in bone cancer care management and forecast of ICU needs based on computed tomography	3
Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT	3
New perspective into mesenchymal stem cells: Molecular mechanisms regulating osteosarcoma	3
Analysis of intercellular communication in the osteosarcoma microenvironment based on single cell sequencing data	3
-AI-assisted diagnostic potential of CT in bone oncology and its impact on clinical decision-making for intensive care	3
Bone metastases from urothelial carcinoma. The dark side of the moon	3
AI based diagnostics product design for osteosarcoma cells microscopy imaging of bone cancer patients using CA-MobileNet V3	3
Use of paclitaxel carried in lipid core nanoparticles in patients with late-stage solid cancers with bone metastases: Lack of toxicity and therapeutic benefits	3
The Harrington plus reconstruction for pelvic and acetabular metastases	2
#24. Mechanical loading-induced changes to the bone microenvironment control bone metastatic breast cancer lesions	2
PTHrP biological domains mediate breast cancer bone osteolysis via TGF-β/SNAI2/ZEB1 pathways	2
Efficacy of replacing actinomycin-D with carboplatin in Ewing sarcoma consolidation treatment: Single-center experience	2
FBXO22 is a potential therapeutic target for recurrent chondrosarcoma	2
Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones	2
Out with the old (not so!) and in with the new	2
Appendicular dedifferentiated chondrosarcoma: A management and survival study from the SEER database	2
#6. Mechanical loading of breast cancer laden bones alters osteocyte mediated bone loss in vivo	2
Imaging evaluation of blood supply changes after chemotherapy of osteosarcoma and its correlation with tumor necrosis rate	2
FGF-23 transmitted tumor – induced hypophosphatemic osteomalacia: A rare case of a young woman with recurrent fractures and review of the literature	2
Implant failure and revision strategies after total spondylectomy for spinal tumors	2
Automated segmentation and source prediction of bone tumors using ConvNeXtv2 Fusion based Mask R-CNN to identify lung cancer metastasis	2
Deep hashing and attention mechanism-based image retrieval of osteosarcoma scans for diagnosis of bone cancer	2
HDAC inhibitors stimulate LIFR when it is repressed by hypoxia or PTHrP in breast cancer	2
Surgical Options for Aggressive Vertebral Hemangiomas：A case series, literature review and treatment recommendations	2
XIST sponges miR-320d to promote chordoma progression by regulating ARF6	2
Indirect bilirubin impairs invasion of osteosarcoma cells via inhibiting the PI3K/AKT/MMP-2 signaling pathway by suppressing intracellular ROS	2
DXA assessment and fracture prevention in hormone positive breast cancer patients after treatment initiation with aromatase inhibitors: A registry-based cohort study	2
Epigenetic control of the vicious cycle	2
All bone metastases are not created equal: Revisiting treatment resistance in renal cell carcinoma	2
The osteoblast in regulation of tumor cell dormancy and bone metastasis	2
Adoption of adjuvant bisphosphonates for early breast cancer into standard clinical practice: Challenges and lessons learnt from comparison of the UK and Australian experience	2
Prosthetic reconstruction following resection of lower extremity bone neoplasms: A systematic review and meta-analysis	2
#2. Homing of intestinal NK and Th1 cells to the tumor site restrains melanoma bone growth in a gut microbiome dependent manner	1

#20. Investigating the response of prostate cancer cells to bone-derived growth factor gradients via fluid-wall microfluidic culture systems	1
Mometasone furoate inhibits tumor progression and promotes apoptosis through activation of the AMPK/mTOR signaling pathway in osteosarcoma	1
Clinical usefulness of 2-hydroxyglutarate as a biomarker in IDH-mutant chondrosarcoma	1
Diagnosis of newly developed multiple myeloma without bone disease detectable on conventional computed tomography (CT) scan by using dual-energy CT	1
Innovation in proximal femoral replacement for oncology patients—A novel eggshell procedure	1
#49. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat diet	1
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations	1
Groenlandicine enhances cisplatin sensitivity in cisplatin-resistant osteosarcoma cells through the BAX/Bcl-2/Caspase-9/Caspase-3 pathway	1
#31. A Phase I/II trial of ATI-2231 with Phase Ia in advanced soild tumor malignancies followed by Phase Ib/II in combination with capecitabine in patients with hormone receptor-positive (HR+) and HER	1
#4. Elucidating the effect of glutamine metabolism in breast-to-bone metastasis	1
Using a combination of gangliosides and cell surface vimentin as surface biomarkers for isolating osteosarcoma cells in microfluidic devices	1
Concurrent capecitabine with external beam radiotherapy versus radiotherapy alone in painful bone metastasis of breast cancer origin	1
Determinants of tumor necrosis and its impact on outcome in patients with Localized osteosarcoma uniformly treated with a response adapted regimen without high dose Methotrexate– A retrospective insti	1
The role of mitochondria-related lncRNAs in characterizing the immune landscape and supervising the prognosis of osteosarcoma	1
The 100 most cited papers on bone metastasis: A bibliometric analysis	1
#23. Elucidating the role of bone marrow stiffness in estrogen signaling in metastatic breast cancer to the bone	1
Epidemiology of spinal metastases, metastatic epidural spinal cord compression and pathologic vertebral compression fractures in patients with solid tumors: A systematic review	1
Chemotherapy-induced adipocyte senescence triggers bone loss through RANKL-mediated osteoclastogenesis	1
A randomized trial comparing LY01011, biosimilar candidate, with the reference product denosumab (Xgeva®) in healthy Chinese subjects	1
#34. The effect of dickkopf-1 (DKK-1) on prostate cancer growth and bone metastasis using the canine osteoblastic Probasco cell line	1
Real-world experiences in patients with Ewing sarcoma treated at a specialist centre in Turkey	1
Auxiliary diagnosis of primary bone tumors based on Machine learning model	1
Single-cell transcriptional profiling in osteosarcoma and the effect of neoadjuvant chemotherapy on the tumor microenvironment	1
Differential expression of angiogenesis markers HSP70, HSP90, VEGF and pERK1/2 in both components of dedifferentiated chondrosarcomas	1
#52. Computational modeling of signaling pathways and cell-cell interactions driving tumor-induced bone disease	1
Percutaneous vertebroplasty/kyphoplasty contributes to the improved outcome in patients with newly diagnosed multiple myeloma: A single center cohort study	1
#28. Identification of key proteins within prostate cancer derived exosomes and their role in priming the pre-metastatic niche	1