FEBS Open Bio

Article	Citations
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Issue Information	64
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Posters Annex	52
Issue Information	49
KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO<	42
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia	37
Targeted recombination of homologous chromosomes using CRISPR‐Cas9	36
Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold	33
Regorafenib as a potential drug for severe COVID‐19: inhibition of inflammasome activation in mice	31
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production	29
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives	27
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21	26
Membrane‐acting biomimetic peptoids against visceral leishmaniasis	26
RETRACTION : LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF<	25
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivatin	24
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL	24
Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics	24
A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology	24
Interaction of RECQL 4 with poly( ADP ‐ribose) is critical for the DNA	24
Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari	23
2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS ‐enhanced PI3K /Akt/	23
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis	22
Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth	21
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics	20

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Microglial dynamics and ferroptosis induction in human iPSC ‐derived neuron–astrocyte–microglia tri‐cultures	18
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Overview of molecular signatures of senescence and associated resources: pros and cons	18
The E3 ubiquitin ligase, RNF219 , suppresses CNOT6L	17
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer	17
Enhancing transporter activity in heterologous expression systems with SAHA : a 2500‐times more potent and odorless alternative to butyrate	17
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms	17
High growth hormone serum partially protects mice against Trypanosoma cruzi infection	16
Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin‐deficient mice	16
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction	16
YAP ‐ TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing	16
The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition	15
Metabolic reprogramming heterogeneity in chronic kidney disease	15
Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling	15
Talks	15
Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus	15
Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data	14
Domain associated with zinc fingers‐containing NF90 ‐ NF45 complex inhibits	14
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone	13
Retraction statement: Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma	13
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation	13
NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2	13
Issue Information	12
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise	12
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Reviewers acknowledgement	12
A potential tumor suppressor role of PLK2 in glioblastoma	12
Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors	12
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Characterization of the promoter region of the murine Catsper2 gene	12
Glycolipids in Parkinson's disease: beyond neuronal function	11
Multi‐omics‐based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis	11
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA –protein interaction studies	11
Serving the scientific community: FEBS Open Bio in 2024	11
RETRACTION : Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus	11
Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer ( NSCLC ) cell culture supernatan	11
Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT	11
Multiple time‐dependent pathophysiological changes in a rabbit model of high‐fat diet‐induced hyperlipidemia	11
Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.	11
Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions	11
Structural investigations on the mitochondrial uncouplers niclosamide and FCCP	11
IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells	10
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A framework for decolonising and diversifying biomedical sciences curricula: rediscovery, representation and readiness	10
Issue Information	10
Prediction of chaperonin GroE substrates using small structural patterns of proteins	10
HIV ‐1 establishes immediate latency in T cells expressing the viral Nef protein	10
Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction	10
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Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes	10
Long noncoding RNAMEG3 inhibits oral squamous cell carcinoma progression via GATA3	9
Polysaccharide utilization loci encoded DUF1735 likely functions as membrane‐bound spacer for carbohydrate active enzymes	9
Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss	9
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach	9
DDX 3 participates in mi RNA biogenesis and RNA interference throug	9
HELQ deficiency impairs the induction of primordial germ cell‐like cells	9
Alfaxalone does not have long‐term effects on goldfish pyramidal neuron action potential properties or GABA A	9
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells	9
An efficient strategy for producing RNA ‐free Nucleocapsid protein of SARS ‐ <	9
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production	9
Earthing effects on mitochondrial function: ATP production and ROS generation	9
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The crystal structure of methanogen McrD , a methyl‐coenzyme M reductase‐associated protein	9
Identification and functional comparison of novel alternatively spliced isoforms of human YAP	9
An open chat with… Johannes Herrmann	9
Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice	8
Small RNA pathways in mammalian oocytes	8
Ensuring image integrity in the digital age	8
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Cancer cells forgo translating m RNA transcribed from genes of nonspecialized tasks	8
Microglia heterogeneity in health and disease	8
The anti‐cancer effect of epigallocatechin‐3‐ O ‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyfla	8
Cell‐specific genome‐scale metabolic modeling of SARS‐CoV ‐2‐infected lung to identify antiviral enzymes	8
Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway	8
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP	8
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NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment	8
Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education	8
Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow	8
Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a	8
FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway	8
A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress	8
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YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana	8
Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes	8
Identification of testicular cancer immune infiltrates and novel immune cell subtypes	8
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeum GtCel45A	8
On subcellular distribution of the zinc finger 469 protein ( ZNF469 ) and observed discrepancy in the localization of endogenous and overexpressed	7
Corrigendum to “Endoplasmic reticulum stress associated with lead (Pb)‐induced olfactory epithelium toxicity in an olfactory dark basal cell line” https://doi.org/10.1002/2211‐5463.13714	7
Issue Information	7
Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays	7
Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and i	7
Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal	7
Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking	7
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli	7
‘Let's work together to pass medical school’: a qualitative study of medical student attitudes to teamwork, competition and collaboration	7
Issue Information	7
Report on the FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference	7
Development of human monoclonal antibodies against TARM1 by yeast display	7
Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy	7
The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring	7
Functional parameters of spermatozoa obtained by a new selection device	7
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches	7
Strengthening the bond with the scientific community: FEBS Open Bio in 2025	7
Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis	7
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice	7
Cotton flower metabolites inhibit SARS‐CoV‐2 main protease	7
Exam‐level analysis of lecture capture viewing and student exam performance	6
Intracellular protein crystallization in living insect cells	6
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines	6
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C	6
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae	6
Sustainable bioplastics manufacturing from renewable sources	6
Retraction statement: miR ‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via	6
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Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer	6
Report on the 2nd MO bility for Vesicle research in Europe ( MOVE ) symposium—2024	6
Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia	6
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps	6
CDK5 interacts with MST2 and modulates the Hippo signalling pathway	6
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control	6
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.	6
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐ NF1 patients and role of	6
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function	6
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Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants	6
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A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers	6
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Real‐world genomic landscape of colon and rectal cancer	6
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer	6
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Correction to “Characterization of the cHS4 insulator in mouse embryonic stem cells”	6
Talks	6
Issue Information	6
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Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions	5
Biochemical characterization and gene structure analysis of the 24‐k D a glutathione transferase sigma from Taenia solium	5
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria	5
Abstracts	5
Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi ‐mediated genetic repression systems	5
HPV18 E6 inhibits α‐ketoglutarate‐induced pyroptosis of esophageal squamous cell carcinoma cells via the P53 /	5
Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders	5
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes	5
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1 ‐4	5
Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media	5
Issue Information	5
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release	5
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Acquired and intrinsic resistance to vemurafenib in BRAF V600E ‐driven m	5
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response	5
Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration	5
RETRACTION : The PI 3 K /m TOR	5
Front Cover	5
Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins	5
RETRACTION : MicroRNA ‐498 Reduces the Proliferation and Invasion of Colorectal Cancer Cells via Targeting Bcl‐2	5
Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells	5
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells	5
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway	5
Hydrostatic pressure activates HIF ‐1α via β‐catenin to promote stemness in breast cancer cells	5
Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss	5
Adenosine A 3 receptor antagonists as anti‐tumor treatment in human pros	5
The role of lipid metabolism in neuronal senescence	5
Identification and analysis of short indels inducing exon extension/shrinkage events	5
Issue Information	5
WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV	5
Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K	5
Structure prediction analysis of human core TIM 23 complex reveals conservation of the protein translocation mechanism	5
Issue Information	5
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen <	5
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation	5
Using a ‘Students as Partners’ model to develop an authentic assessment promoting employability skills in undergraduate life science education	5
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy	5
SMARCA4 mutations and expression in lung adenocarcinoma: prognostic significance and impact on the immunotherapy response	5
Digital twins to accelerate target identification and drug development for immune‐mediated disorders	5
Hippocampal tau‐induced GRIN3A deficiency in Alzheimer's disease	4
Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation	4
The protein tyrosine phosphatase PPH ‐7 is required for fertility and embryonic development in C. elegans	4
Insights into the identification and evolutionary conservation of key genes in the transcriptional circuits of meiosis initiation and commitment in budding yeast	4
Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs	4
Nuclear endonuclease G controls cell proliferation in ovarian cancer	4
Corrigendum to: Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp	4
Expression and purification of the receptor‐binding domain of SARS‐CoV‐2 spike protein in mammalian cells for immunological assays	4
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Determination of the optimal connector length to enhance stability of backbone‐circularized granulocyte colony‐stimulating factor	4
Abstracts	4
Peptide mimetic NC114 induces growth arrest by preventing PKCδ activation and FOXM1 nuclear translocation in colorectal cancer cells	4
Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine	4
Comparative genome analysis of three classical E. coli cloning strains designed for blue/white selection: JM83, JM109 and XL1‐Blue	4
A novel plasmid‐based experimental system in Saccharomyces cerevisiae that enables the introduction of 10 different plasmids into cells	4
Cardiovascular risk of dietary trimethylamine oxide precursors and the therapeutic potential of resveratrol and its derivatives	4
Intercompartmental communication in senescence	4
Issue Information	4
Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE	4
LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes	4
Identifying prognostic targets in metastatic prostate cancer beyond AR	4
Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP	4
Rapid isolation and cryo‐EM characterization of synaptic vesicles from mammalian brain	4
Exploring gene regulatory interaction networks and predicting therapeutic molecules for hypopharyngeal cancer and EGFR ‐mutated lung adenocarcinoma	4
Withdrawal statement: [Liu, X., Qiao, L., Zhang, H., Zhang, C., Ding, R., Kang, J., Liu, Y., Lin, J. and Yan, X. (2023), Argonaute 2 regulates LPS‐induced inflammation in microglial BV2 cells by targe	4
Alcohol induces α2‐6sialo mucin O ‐glycans that kill U 937 macrophages mediated by sialic acid‐bin	4
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A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans	4
Retraction statement: microRNA ‐497 inhibits cell proliferation and induces apoptosis by targeting YAP1	4
Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis	4
Dihydroorotate dehydrogenase ( DHODH ) regulates trophoblast syncytialization through organelle stress–induced cellular senescence	4
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation	4
Neutrophil and macrophage crosstalk might be a potential target for liver regeneration	4
Oleanolic acid alleviates obesity‐induced skeletal muscle atrophy via the PI3K /Akt signaling pathway	4
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL /6 mice	4
Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality	4
The role of circular RNAs in regulating cytokine signaling in cancer	4
TGF ‐β effects on adipogenesis of 3T3 ‐ L1 cells differ in	4
Issue Information	4
Cylindracin, a Cys‐rich protein expressed in the fruiting body of Cyclocybe cylindracea , inhibits growth of filamentous fungi but not yeasts or bacteria	4
Lipid dysmetabolism in ceruloplasmin‐deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses	4
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Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice	4
Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism	4
Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway	4
Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans	4