FEBS Open Bio

Article	Citations
	113
Issue Information	61
Issue Information	54
RETRACTION: LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF‐1 Signaling	51
Posters Annex	50
Issue Information	49
A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology	45
KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO<	40
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia	40
Targeted recombination of homologous chromosomes using CRISPR‐Cas9	38
Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold	37
Regorafenib as a potential drug for severe COVID‐19: inhibition of inflammasome activation in mice	36
Overview of molecular signatures of senescence and associated resources: pros and cons	33
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis	32
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis	32
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization	31
Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics	27
2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS ‐enhanced PI3K /Akt/	27
Interaction of RECQL 4 with poly( ADP ‐ribose) is critical for the DNA	27
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivatin	27
Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari	27
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL	26
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives	25
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21	24
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor	23

Analgesic effects of nerve growth factor‐directed monoclonal antibody on diabetic neuralgia in an animal model	23
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics	23
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production	22
Membrane‐acting biomimetic peptoids against visceral leishmaniasis	22
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A potential tumor suppressor role of PLK2 in glioblastoma	20
Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin	20
Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells	20
Talks	18
High growth hormone serum partially protects mice against Trypanosoma cruzi infection	18
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction	18
Retraction statement: Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma	16
Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus	15
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation	15
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation	15
The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition	14
NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2	14
Metabolic reprogramming heterogeneity in chronic kidney disease	14
Development and single‐particle analysis of hybrid extracellular vesicles fused with liposomes using viral fusogenic proteins	14
The E3 ubiquitin ligase, RNF219 , suppresses CNOT6L	13
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer	13
Science students' perspectives on how to decrease the stigma of failure	13
Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin‐deficient mice	13
YAP ‐ TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing	13
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise	13
Enhancing transporter activity in heterologous expression systems with SAHA : a 2500‐times more potent and odorless alternative to butyrate	13
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms	13
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone	13
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Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors	12
Viral and cellular translation during SARS‐CoV‐2 infection	12
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation	12
Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT	12
Serving the scientific community: FEBS Open Bio in 2024	12
The mTOR–lysosome axis at the centre of ageing	12
Issue Information	12
IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells	12
Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex	12
Reviewers acknowledgement	12
Characterization of the promoter region of the murine Catsper2 gene	12
Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction	11
Glycolipids in Parkinson's disease: beyond neuronal function	11
A framework for decolonising and diversifying biomedical sciences curricula: rediscovery, representation and readiness	11
Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions	11
RETRACTION: Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus	11
The composition of the lung microbiome differs between patients with dermatomyositis and rheumatoid arthritis associated with interstitial lung disease	11
Multiple time‐dependent pathophysiological changes in a rabbit model of high‐fat diet‐induced hyperlipidemia	11
Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival	11

Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.	11
Multi‐omics‐based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis	11
Overexpression of BcERF3 increases the biosynthesis of saikosaponins in Bupleurum chinense	11
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Earthing effects on mitochondrial function: ATP production and ROS generation	10
An open chat with… Johannes Herrmann	10
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Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells	10
Long noncoding RNAMEG3 inhibits oral squamous cell carcinoma progression via GATA3	10
Structural investigations on the mitochondrial uncouplers niclosamide and FCCP	10
Issue Information	10
Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway	10
HELQ deficiency impairs the induction of primordial germ cell‐like cells	10
Prediction of chaperonin GroE substrates using small structural patterns of proteins	10
Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss	9
Identification and functional comparison of novel alternatively spliced isoforms of human YAP	9
A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress	9
Chloroplast genomes of two Pueraria DC. species: sequencing, comparative analysis and molecular marker development	9
Ensuring image integrity in the digital age	9
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Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes	9
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP	9
Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice	9
Polysaccharide utilization loci encoded DUF1735 likely functions as membrane‐bound spacer for carbohydrate active enzymes	9
Alfaxalone does not have long‐term effects on goldfish pyramidal neuron action potential properties or GABA A	9
The crystal structure of methanogen McrD , a methyl‐coenzyme M reductase‐associated protein	9
Entering the second decade: FEBS Open Bio in 2022	9
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An efficient strategy for producing RNA ‐free Nucleocapsid protein of SARS ‐ <	9
DDX 3 participates in mi RNA biogenesis and RNA interference throug	9
FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway	9
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production	9
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach	9
Issue Information	9
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Microglia heterogeneity in health and disease	8
Identification of testicular cancer immune infiltrates and novel immune cell subtypes	8
Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow	8
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeum GtCel45A	8
Cell‐specific genome‐scale metabolic modeling of SARS‐CoV ‐2‐infected lung to identify antiviral enzymes	8
The anti‐cancer effect of epigallocatechin‐3‐ O ‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyfla	8
Issue Information	8
NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment	8
‘Let's work together to pass medical school’: a qualitative study of medical student attitudes to teamwork, competition and collaboration	8
Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a	8
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches	8
Reviewers acknowledgement	8
Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education	8
Cancer cells forgo translating m RNA transcribed from genes of nonspecialized tasks	8
Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking	7
Strengthening the bond with the scientific community: FEBS Open Bio in 2025	7
Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays	7
Cotton flower metabolites inhibit SARS‐CoV‐2 main protease	7
The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring	7
On subcellular distribution of the zinc finger 469 protein ( ZNF469 ) and observed discrepancy in the localization of endogenous and overexpressed	7
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice	7
Issue Information	7
Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo	7
Report on the FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference	7
Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis	7
Metallodrugs: an approach against invasion and metastasis in cancer treatment	7
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli	7
Corrigendum to “Endoplasmic reticulum stress associated with lead (Pb)‐induced olfactory epithelium toxicity in an olfactory dark basal cell line” https://doi.org/10.1002/2211‐5463.13714	7
FEBS Open Bio: past, present and future	7
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells	7
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR‐Cas9 screen	7
Functional parameters of spermatozoa obtained by a new selection device	7
The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells	7
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae	6
Real‐world genomic landscape of colon and rectal cancer	6
Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants	6
Report on the 2nd MO bility for Vesicle research in Europe ( MOVE ) symposium—2024	6
Retraction statement: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling	6
Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy	6
Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition	6
Intracellular protein crystallization in living insect cells	6
Issue Information	6
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C	6
CDK5 interacts with MST2 and modulates the Hippo signalling pathway	6
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐ NF1 patients and role of	6

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Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal	6
A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers	6
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.	6
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer	6
Issue Information	6
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines	6
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps	6
Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia	6
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function	6
Talks	6
Issue Information	6
Learning objectives: an epiphany	6
Correction to “Characterization of the cHS4 insulator in mouse embryonic stem cells”	6
Issue Information	6
Exam‐level analysis of lecture capture viewing and student exam performance	6
Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo	5
Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders	5
Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN	5
RETRACTION: MicroRNA‐498 Reduces the Proliferation and Invasion of Colorectal Cancer Cells via Targeting Bcl‐2	5
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Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss	5
Structure prediction analysis of human core TIM 23 complex reveals conservation of the protein translocation mechanism	5
Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells	5
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Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media	5
Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K	5
Biochemical characterization and gene structure analysis of the 24‐k D a glutathione transferase sigma from Taenia solium	5
Acquired and intrinsic resistance to vemurafenib in BRAF V600E ‐driven m	5
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response	5
Adenosine A 3 receptor antagonists as anti‐tumor treatment in human pros	5
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes	5
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation	5
Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins	5
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release	5
SMARCA4 mutations and expression in lung adenocarcinoma: prognostic significance and impact on the immunotherapy response	5
Issue Information	5
HPV18 E6 inhibits α‐ketoglutarate‐induced pyroptosis of esophageal squamous cell carcinoma cells via the P53 /	5
Using a ‘Students as Partners’ model to develop an authentic assessment promoting employability skills in undergraduate life science education	5
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway	5
Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi ‐mediated genetic repression systems	5
The dynamics of cell death patterns and regeneration during acute liver injury in mice	5
Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration	5
Front Cover	5
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy	5
WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV	5
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells	5
hnRNP A1 and hnRNP C associate with miR‐17 and miR‐18 in thyroid cancer cells	5
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen <	5
Isolation and characterization of peritoneal microvascular pericytes	5
Identification and analysis of short indels inducing exon extension/shrinkage events	5
The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation	5
Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions	5
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria	5
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1 ‐4	5
Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE	4
Identifying prognostic targets in metastatic prostate cancer beyond AR	4
Corrigendum to: Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells	4
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Issue Information	4
A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans	4
Withdrawal statement: [Liu, X., Qiao, L., Zhang, H., Zhang, C., Ding, R., Kang, J., Liu, Y., Lin, J. and Yan, X. (2023), Argonaute 2 regulates LPS‐induced inflammation in microglial BV2 cells by targe	4
Retraction statement: Shao, L., Zhang, X. and Yao, Q. (2020), The F‐box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin‐mediated degradation of Snail. FEBS Open B	4
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Determination of the optimal connector length to enhance stability of backbone‐circularized granulocyte colony‐stimulating factor	4
Exploring gene regulatory interaction networks and predicting therapeutic molecules for hypopharyngeal cancer and EGFR ‐mutated lung adenocarcinoma	4
The protein tyrosine phosphatase PPH ‐7 is required for fertility and embryonic development in C. elegans	4
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL /6 mice	4
Identification of ferroptosis‐related genes as potential biomarkers of tongue squamous cell carcinoma using an integrated bioinformatics approach	4
Insights into the identification and evolutionary conservation of key genes in the transcriptional circuits of meiosis initiation and commitment in budding yeast	4
Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality	4
Expression and purification of the receptor‐binding domain of SARS‐CoV‐2 spike protein in mammalian cells for immunological assays	4
Abstracts	4
Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP	4
ARL2 is required for homologous recombination repair and colon cancer stem cell survival	4
Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis	4
Corrigendum to: Identification and expression analysis of LEA gene family members in pepper (Capsicum annuum L.) https://doi.org/10.1002/2211‐5463.13718	4
Cardiovascular risk of dietary trimethylamine oxide precursors and the therapeutic potential of resveratrol and its derivatives	4
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation	4
Neutrophil and macrophage crosstalk might be a potential target for liver regeneration	4
Rapid isolation and cryo‐EM characterization of synaptic vesicles from mammalian brain	4
The role of circular RNAs in regulating cytokine signaling in cancer	4
Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway	4
Retraction statement: microRNA‐497 inhibits cell proliferation and induces apoptosis by targeting YAP1 in human hepatocellular carcinoma	4
Issue Information	4
Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism	4
Peptide mimetic NC114 induces growth arrest by preventing PKCδ activation and FOXM1 nuclear translocation in colorectal cancer cells	4
Lipid dysmetabolism in ceruloplasmin‐deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses	4
Issue Information	4
Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells	4
Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis	4
Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine	4