FEBS Open Bio

Article	Citations
	128
Issue Information	62
Issue Information	53
RETRACTION: LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF‐1 Signaling	52
Posters Annex	52
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives	47
Issue Information	43
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia	41
KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO<	41
Targeted recombination of homologous chromosomes using CRISPR‐Cas9	39
Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold	38
Regorafenib as a potential drug for severe COVID‐19: inhibition of inflammasome activation in mice	35
2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS ‐enhanced PI3K /Akt/	31
Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics	28
Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari	28
Interaction of RECQL 4 with poly( ADP ‐ribose) is critical for the DNA	28
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivatin	28
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis	27
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis	27
Membrane‐acting biomimetic peptoids against visceral leishmaniasis	24
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics	24
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization	23
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL	23
Overview of molecular signatures of senescence and associated resources: pros and cons	23
Analgesic effects of nerve growth factor‐directed monoclonal antibody on diabetic neuralgia in an animal model	22

A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology	22
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21	22
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Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production	21
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A potential tumor suppressor role of PLK2 in glioblastoma	19
Domain associated with zinc fingers‐containing NF90 ‐ NF45 complex inhibits	18
Metabolic reprogramming heterogeneity in chronic kidney disease	18
The E3 ubiquitin ligase, RNF219 , suppresses CNOT6L	16
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction	16
Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells	16
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation	16
Talks	15
High growth hormone serum partially protects mice against Trypanosoma cruzi infection	15
Retraction statement: Ubiquitin ligase SMURF1 functions as a prognostic marker and promotes growth and metastasis of clear cell renal cell carcinoma	14
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms	14
Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus	14
Phenotypical and biochemical characterization of murine psoriasiform and fibrotic skin disease models in Stabilin‐deficient mice	14
SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation	14
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation	14
YAP ‐ TEAD inhibition is associated with upregulation of an androgen receptor mediated transcription program providing	14
The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition	13
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise	13
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone	13
NMR screening of low molecular weight inhibitors targeting the papain‐like protease (PLPro) of SARS‐CoV‐2	13
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer	13
Viral and cellular translation during SARS‐CoV‐2 infection	13
Characterization of the promoter region of the murine Catsper2 gene	13
Issue Information	12
Reviewers acknowledgement	12
Metabolic changes induced by DNA damage in Ramos cells: exploring the role of mTORC1 complex	12
Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors	12
Development and single‐particle analysis of hybrid extracellular vesicles fused with liposomes using viral fusogenic proteins	12
Serving the scientific community: FEBS Open Bio in 2024	12
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Enhancing transporter activity in heterologous expression systems with SAHA : a 2500‐times more potent and odorless alternative to butyrate	12
Ezetimibe inhibits the migration and invasion of triple‐negative breast cancer cells by targeting TGFβ2 and EMT	12
RETRACTION: Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus	11
HIV ‐1 establishes immediate latency in T cells expressing the viral Nef protein	11
Multiple time‐dependent pathophysiological changes in a rabbit model of high‐fat diet‐induced hyperlipidemia	11
IFNγ induces Bcl3 expression by JAK1/STAT1/p65 signaling, resulting in increased IL‐8 expression in ovarian cancer cells	11
Overexpression of BcERF3 increases the biosynthesis of saikosaponins in Bupleurum chinense	11
Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival	11
Evaluation of binding activities of a putative lipoprotein LIC_13355 of Leptospira spp.	11
Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction	11
Glycolipids in Parkinson's disease: beyond neuronal function	11
A framework for decolonising and diversifying biomedical sciences curricula: rediscovery, representation and readiness	11
Multi‐omics‐based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis	10
Issue Information	10

Reduced FRG1 expression promotes angiogenesis via activation of the FGF2‐mediated ERK/AKT pathway	10
HELQ deficiency impairs the induction of primordial germ cell‐like cells	10
Earthing effects on mitochondrial function: ATP production and ROS generation	10
Structural investigations on the mitochondrial uncouplers niclosamide and FCCP	10
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An open chat with… Johannes Herrmann	10
Long noncoding RNAMEG3 inhibits oral squamous cell carcinoma progression via GATA3	10
Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions	10
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Prediction of chaperonin GroE substrates using small structural patterns of proteins	10
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production	10
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells	9
Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss	9
DDX 3 participates in mi RNA biogenesis and RNA interference throug	9
Alfaxalone does not have long‐term effects on goldfish pyramidal neuron action potential properties or GABA A	9
Issue Information	9
The crystal structure of methanogen McrD , a methyl‐coenzyme M reductase‐associated protein	9
Myeloperoxidase inhibition protects bone marrow mononuclear cells from DNA damage induced by the TOP	9
Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice	9
Polysaccharide utilization loci encoded DUF1735 likely functions as membrane‐bound spacer for carbohydrate active enzymes	9
A systems biological analysis of the ATF4‐GADD34‐CHOP regulatory triangle upon endoplasmic reticulum stress	9
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Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach	9
An efficient strategy for producing RNA ‐free Nucleocapsid protein of SARS ‐ <	9
Identification and functional comparison of novel alternatively spliced isoforms of human YAP	9
FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway	9
Ensuring image integrity in the digital age	9
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Time‐dependent effects of hypoxia on cell metabolism, signaling, and iron homeostasis in the hematopoietic progenitor model KG1a	8
Microglia heterogeneity in health and disease	8
‘Let's work together to pass medical school’: a qualitative study of medical student attitudes to teamwork, competition and collaboration	8
NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment	8
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Lkb1 loss in regulatory T cells leads to dysregulation of hematopoietic stem cell expansion and differentiation in bone marrow	8
Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education	8
The anti‐cancer effect of epigallocatechin‐3‐ O ‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyfla	8
Identification of testicular cancer immune infiltrates and novel immune cell subtypes	8
Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes	8
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches	8
The first crystal structure of a family 45 glycoside hydrolase from a brown‐rot fungus, Gloeophyllum trabeum GtCel45A	8
Cancer cells forgo translating m RNA transcribed from genes of nonspecialized tasks	8
Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays	7
Issue Information	7
Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking	7
On subcellular distribution of the zinc finger 469 protein ( ZNF469 ) and observed discrepancy in the localization of endogenous and overexpressed	7
Oxidative stress in the tumor microenvironment in gastric cancer and its potential role in immunotherapy	7
Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer	7
Intermittent induction of LEA peptide by lactose enhances the expression of insecticidal proteins in Bacillus thuringiensis	7
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells	7
Retraction: Kinesin family member 3A stimulates cell proliferation, migration, and invasion of bladder cancer cells in vitro and in vivo	7
Issue Information	7
Strengthening the bond with the scientific community: FEBS Open Bio in 2025	7
Analysis of the regulation of undecaprenyl diphosphate dephosphorylation in Escherichia coli	7
The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells	7
Development of a fully human anti‐GITR antibody with potent antitumor activity using H2L2 mice	7
Report on the FEBS‐IUBMB‐ENABLE 1st International Molecular Biosciences PhD and Postdoc Conference	7
Corrigendum to “Endoplasmic reticulum stress associated with lead (Pb)‐induced olfactory epithelium toxicity in an olfactory dark basal cell line” https://doi.org/10.1002/2211‐5463.13714	7
Cell‐specific genome‐scale metabolic modeling of SARS‐CoV ‐2‐infected lung to identify antiviral enzymes	7
The cryo‐EM structure of full‐length RAD52 protein contains an undecameric ring	7
Functional parameters of spermatozoa obtained by a new selection device	7
The splicing factor DHX38/PRP16 is required for ovarian clear cell carcinoma tumorigenesis, as revealed by a CRISPR‐Cas9 screen	7
Metallodrugs: an approach against invasion and metastasis in cancer treatment	7
Issue Information	6
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response	6
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines	6
A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers	6
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C	6
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function	6
Retraction statement: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling	6
Issue Information	6
Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition	6
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.	6
Front Cover	6
Issue Information	6
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae	6
Real‐world genomic landscape of colon and rectal cancer	6
Report on the 2nd MO bility for Vesicle research in Europe ( MOVE ) symposium—2024	6
Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants	6
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Talks	6

Benefits of exercise on cognitive impairment in alcohol use disorder following alcohol withdrawal	6
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer	6
Intracellular protein crystallization in living insect cells	6
Issue Information	6
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps	6
CDK5 interacts with MST2 and modulates the Hippo signalling pathway	6
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐ NF1 patients and role of	6
Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia	6
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Cotton flower metabolites inhibit SARS‐CoV‐2 main protease	6
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Exam‐level analysis of lecture capture viewing and student exam performance	6
Correction to “Characterization of the cHS4 insulator in mouse embryonic stem cells”	6
Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo	6
Structure prediction analysis of human core TIM 23 complex reveals conservation of the protein translocation mechanism	5
Malus pumila Mill. cv Annurca apple extract might be therapeutically useful against oxidative stress and patterned hair loss	5
Biochemical and in silico identification of the active site and the catalytic mechanism of the circadian deadenylase HESPERIN	5
SMARCA4 mutations and expression in lung adenocarcinoma: prognostic significance and impact on the immunotherapy response	5
hnRNP A1 and hnRNP C associate with miR‐17 and miR‐18 in thyroid cancer cells	5
Feeder cells treated with ethanol can be used to maintain self‐renewal and pluripotency of human pluripotent stem cells	5
Diagnostic and therapeutic targeting of pathological tau proteins in neurodegenerative disorders	5
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Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions	5
Identification and analysis of short indels inducing exon extension/shrinkage events	5
The dynamics of cell death patterns and regeneration during acute liver injury in mice	5
WDHD1 is over‐expressed in nasopharyngeal carcinoma and may control the expression of ITGAV	5
Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration	5
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Hesperidin enhances intestinal barrier function in Caco‐2 cell monolayers via AMPK‐mediated tight junction‐related proteins	5
On the difficulties of characterizing weak protein interactions that are critical for neurotransmitter release	5
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation	5
HPV18 E6 inhibits α‐ketoglutarate‐induced pyroptosis of esophageal squamous cell carcinoma cells via the P53 /	5
Biochemical characterization and gene structure analysis of the 24‐k D a glutathione transferase sigma from Taenia solium	5
Using a ‘Students as Partners’ model to develop an authentic assessment promoting employability skills in undergraduate life science education	5
Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi ‐mediated genetic repression systems	5
Adenosine A 3 receptor antagonists as anti‐tumor treatment in human pros	5
The role of lipid metabolism in neuronal senescence	5
Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K	5
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes	5
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N‐cadherin pathway	5
Beta cell regeneration upon magainin and growth hormone treatment as a possible alternative to insulin therapy	5
Intrabacterial lipid inclusion‐associated proteins: a core machinery conserved from saprophyte Actinobacteria to the human pathogen <	5
Flow cytometric resolution of yeast is affected by enzymatic treatment and culture media	5
Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells	5
Issue Information	5
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria	5
Acquired and intrinsic resistance to vemurafenib in BRAF V600E ‐driven m	5
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1 ‐4	5
RETRACTION: MicroRNA‐498 Reduces the Proliferation and Invasion of Colorectal Cancer Cells via Targeting Bcl‐2	5
Isolation and characterization of peritoneal microvascular pericytes	5
The role of RNA regulators, quorum sensing and c‐di‐GMP in bacterial biofilm formation	5
Cylindracin, a Cys‐rich protein expressed in the fruiting body of Cyclocybe cylindracea , inhibits growth of filamentous fungi but not yeasts or bacteria	4
Nuclear endonuclease G controls cell proliferation in ovarian cancer	4
A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans	4
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Expression and purification of the receptor‐binding domain of SARS‐CoV‐2 spike protein in mammalian cells for immunological assays	4
Lipid dysmetabolism in ceruloplasmin‐deficient mice revealed both in vivo and ex vivo by MRI, MRS and NMR analyses	4
Issue Information	4
Obesity‐induced oxidative stress and mitochondrial dysfunction negatively affect sperm quality	4
Determination of the optimal connector length to enhance stability of backbone‐circularized granulocyte colony‐stimulating factor	4
Insights into the identification and evolutionary conservation of key genes in the transcriptional circuits of meiosis initiation and commitment in budding yeast	4
Neutrophil and macrophage crosstalk might be a potential target for liver regeneration	4
Rapid isolation and cryo‐EM characterization of synaptic vesicles from mammalian brain	4
Alcohol induces α2‐6sialo mucin O ‐glycans that kill U 937 macrophages mediated by sialic acid‐bin	4
Comparative genome analysis of three classical E. coli cloning strains designed for blue/white selection: JM83, JM109 and XL1‐Blue	4
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LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes	4
Issue Information	4
Kinetic characterization of amino acid activation by aminoacyl‐tRNA synthetases using radiolabelled γ‐[32P]ATP	4
Retraction statement: microRNA‐497 inhibits cell proliferation and induces apoptosis by targeting YAP1 in human hepatocellular carcinoma	4
Retraction statement: Shao, L., Zhang, X. and Yao, Q. (2020), The F‐box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin‐mediated degradation of Snail. FEBS Open B	4
Titanium particles inhibit bone marrow mesenchymal stem cell osteogenic differentiation through the MAPK signaling pathway	4
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Functional analysis of the N‐terminal region of acetylxylan esterase from Caldanaerobacter subterraneus subsp. tengcongensis	4
Hippocampal tau‐induced GRIN3A deficiency in Alzheimer's disease	4
Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine	4
Microbiological investigation of pregnancies following vaginal radical trachelectomy using 16S rRNA sequencing of FFPE	4
Identifying prognostic targets in metastatic prostate cancer beyond AR	4
Oleanolic acid alleviates obesity‐induced skeletal muscle atrophy via the PI3K /Akt signaling pathway	4
A novel plasmid‐based experimental system in Saccharomyces cerevisiae that enables the introduction of 10 different plasmids into cells	4
Corrigendum to: Determination of the optimal concentration and duration of C5aR antagonist application in an inflammatory model of human dental pulp cells	4
Issue Information	4
Abstracts	4
Peptide mimetic NC114 induces growth arrest by preventing PKCδ activation and FOXM1 nuclear translocation in colorectal cancer cells	4
ARL2 is required for homologous recombination repair and colon cancer stem cell survival	4
Accumulation of TERT in mitochondria exerts two opposing effects on apoptosis	4
Withdrawal statement: [Liu, X., Qiao, L., Zhang, H., Zhang, C., Ding, R., Kang, J., Liu, Y., Lin, J. and Yan, X. (2023), Argonaute 2 regulates LPS‐induced inflammation in microglial BV2 cells by targe	4
Corrigendum to: Identification and expression analysis of LEA gene family members in pepper (Capsicum annuum L.) https://doi.org/10.1002/2211‐5463.13718	4
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation	4
The role of circular RNAs in regulating cytokine signaling in cancer	4
The protein tyrosine phosphatase PPH ‐7 is required for fertility and embryonic development in C. elegans	4
Fluoxetine partially alleviates inflammation in the kidney of socially stressed male C57 BL /6 mice	4
Structures of distantly related interacting protein homologs are less divergent than non‐interacting homologs	4
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays	4
Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation	4