FEBS Open Bio

Article	Citations
CoCl2‐triggered pseudohypoxic stress induces proteasomal degradation of SIRT4 via polyubiquitination of lysines K78 and K299	120
A quantitative comparison of antibodies against epitope tags for immunofluorescence detection	104
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Issue Information	51
Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production	50
Overexpressed Smurf1 is degraded in glioblastoma cells through autophagy in a p62‐dependent manner	49
An open chat with… Laszlo Nagy	37
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Retraction: IFITM3 promotes hepatocellular carcinoma invasion and metastasis by regulating MMP9 through p38/MAPK signaling	36
Real‐world genomic landscape of colon and rectal cancer	36
Retraction statement: Wu, H., He, Y., Chen, H., Liu, Y., Wei, B., Chen, G., Lin, H. and Lin, H. (2019), LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.	35
RETRACTION: NGF Protects Neuroblastoma Cells Against β‐Amyloid‐Induced Apoptosis via the Nrf2/HO‐1 pathway	35
Retraction statement: Luo L, Liu H and Xi Q (2018) Trastuzumab induces PUMA‐dependent apoptosis and inhibits tumor growth in gastric cancer. FEBS Open Bio 8, 1911–1919.	33
Retraction statement: Sirtuin 6 contributes to migration and invasion of osteosarcoma cells via the ERK1/2/MMP9 pathway	32
Retraction statement: miR‐944 inhibits metastasis of gastric cancer by preventing the epithelial–mesenchymal transition via MACC1/Met/AKT signaling	31
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization	29
Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer	29
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Biogenesis of mitochondrial β‐barrel membrane proteins	25
Cytochrome P450 2A6 is associated with macrophage polarization and is a potential biomarker for hepatocellular carcinoma	24
Male triploid oysters of Crassostrea gigas exhibit defects in mitosis and meiosis during early spermatogenesis	24
Wheat‐ghretropins: novel ghrelin‐releasing peptides derived from wheat protein	23
Issue Information	23
Store‐operated calcium entry mediates hyperalgesic responses during neuropathy	22
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Redefining online biology education: a study on interactive branched video utilisation and student learning experiences	21
Identification of sodium homeostasis genes in Camelus bactrianus by whole transcriptome sequencing	21
Phosphorylation of Akt at Thr308 regulates p‐eNOS Ser1177 during physiological conditions	21
FEBS fellowships: supporting excellent science for over four decades	20
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CXCR4 promotes gefitinib resistance of Huh7 cells by activating the c‐Met signaling pathway	20
Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene	19
Actin‐related protein 5 suppresses the cooperative activation of cardiac gene transcription by myocardin and MEF2	19
Accumulation of amyloid beta (Aβ) and amyloid precursor protein (APP) in tumors formed by a mouse xenograft model of inflammatory breast cancer	19
Mechanism of imidazole inhibition of a GH1 β‐glucosidase	19
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Targeted recombination of homologous chromosomes using CRISPR‐Cas9	19
Learning objectives: an epiphany	18
A redox‐active HybG‐HypD scaffold complex is required for optimal ATPase activity during [NiFe]‐hydrogenase maturation in Escherichia coli	18
Relationship between anticancer sensitivities and cellular respiration properties in 5‐fluorouracil‐resistant HCT116 human colorectal cancer cells	18
Integrative investigation of the TF–miRNA coregulatory network involved in the inhibition of breast cancer cell proliferation by resveratrol	18
Issue Information	18
Development of a novel peptide inhibitor of subtilisin BPN′	17
Issue Information	17
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Inhibition of miR‐93‐5p promotes osteogenic differentiation in a rabbit model of trauma‐induced osteonecrosis of the femoral head	17
Reviving lost binding sites: Exploring calcium‐binding site transitions between human and murine CD23	16
Three‐dimensional, PEG‐based hydrogels induce spheroid formation and enhance viability of A2058 melanoma cells	16
Comprehensive optimization of a reporter assay toolbox for three distinct CRISPR‐Cas systems	16
Membraneless organelles: a smart design for metabolic control	16
Wor1‐regulated ferroxidases contribute to pigment formation in opaque cells of Candida albicans	15
Tyr76 is essential for the cold adaptation of a class II glutaredoxin 4 with a heat‐labile structure from the Arctic bacteriumSphingomonassp.	15
Identification and characterization of a novel glutaminase inhibitor	15
Genomic analysis of Neisseria elongata isolate from a patient with infective endocarditis	15
Chrysin 7‐O‐β‐d‐glucopyranoside increases hepatic low‐density lipoprotein receptor expression through AMP‐activated protein kinase activation	15
Complement C5a‐triggered differentiated HL‐60 stimulates migration of THP‐1 monocytic leukocytes via secretion of CCL2	15
Talks	15
Issue Information	14
Mitochondrial cytochrome c shot towards histone chaperone condensates in the nucleus	14
Prognostic significance of the rhoGTPase RHOVand its role in tumor immune cell infiltration: a comprehensive pan‐cancer analysis	14
Suppression of intrahepatic cholangiocarcinoma cell growth by SKI via upregulation of the CDK inhibitor p21	14
Lewis fucose is a key moiety for the recognition of histo‐blood group antigens by GI.9 norovirus, as revealed by structural analysis	14
Pulmonary ACE2 expression in neonatal and adult rats	14
N6‐isopentenyladenosine inhibits aerobic glycolysis in glioblastoma cells by targeting PKM2 expression and activity	14
Is allostery a fuzzy concept?	13
Issue Information	13
Regulation of cardiac fibrosis in mice with TAC/DOCA‐induced HFpEF by resistin‐like molecule gamma and adenylate cyclase 1	13
Dexamethasone induces p21cip1/waf1 expression via FoxO3a independently of the Lamin A/C‐HDAC2 interaction in Ataxia Telangiectasia	13
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Cadherin‐6 is a novel mediator for the migration of mesenchymal stem cells to glioblastoma cells in response to stromal cell‐derived factor‐1	13
The interplay between pathogens and Atg8 family proteins: thousand‐faced interactions	13
Integrative analysis of immune‐related signature profiles in eosinophilic chronic rhinosinusitis with nasal polyposis	12
Cpeb1 expression is post‐transcriptionally regulated by AUF1, CPEB1, and microRNAs	12
Haemophilus influenzae Protein D antibody suppression in a multi‐component vaccine formulation	12
SNRPC promotes hepatocellular carcinoma cell motility by inducing epithelial‐mesenchymal transition	12

Inhibition of PRMT1 alleviates sepsis‐induced acute kidney injury in mice by blocking the TGF‐β1 and IL‐6 trans‐signaling pathways	12
UbiN, a novel Rhodobacter capsulatus decarboxylative hydroxylase involved in aerobic ubiquinone biosynthesis	12
RIP3‐mediated necroptosis increases neuropathic pain via microglia activation: necrostatin‐1 has therapeutic potential	12
A mouse model of lung cancer induced via intranasal injection for anticancer drug screening and evaluation of pathology	12
CCR7 and its related molecules may be potential biomarkers of pulmonary arterial hypertension	12
Establishment and characterization of a primary cell culture derived from external auditory canal squamous cell carcinoma	12
Structural and functional characterization of a plant alpha‐actinin	12
Toll‐like receptor 9 signaling in chronic lymphocytic leukemia cell lines	12
New regulators of the tetracycline‐inducible gene expression system identified by chemical and genetic screens	12
A brief overview of BNIP3L/NIX receptor‐mediated mitophagy	12
Characterisation of a common hotspot variant in acute intermittent porphyria sheds light on the mechanism of hydroxymethylbilane synthase function	11
Preclinical efficacy and toxicity studies of a highly specific chimeric anti‐CD47 antibody	11
Comparative transcriptomics of the Djungarian hamster hypothalamus during short photoperiod acclimation and spontaneous torpor	11
Inhibition of p53 and ATRX increases telomeric recombination in primary fibroblasts	11
Deletion of gmfA induces keratocyte‐like migration inDictyostelium	11
RAB31 in glioma‐derived endothelial cells promotes glioma cell invasion via extracellular vesicle‐mediated enrichment of MYO1C	11
Structural and functional insights into lysine acetylation of cytochrome c using mimetic point mutants	11
Novel aspects of the phosphorylation and structure of pathological tau: implications for tauopathy biomarkers	11
Single‐cell transcriptome analysis of male chicken germ cells reveals changes in signaling pathway‐related gene expression profiles during mitotic arrest	10
Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD	10
Depletion of CTCF disrupts PSG gene expression in the human trophoblast cell line Swan 71	10
Reduced TREM2 activation in microglia of patients with Alzheimer's disease	10
Active biopackaging produced from by‐products and waste from food and marine industries	10
Posters Annex	10
Overexpression of cyclin‐dependent kinase 1 in esophageal squamous cell carcinoma and its clinical significance	10
Talks	10
A Sandwich‐model experiment with personal response systems on epigenetics: insights into learning gain, student engagement and satisfaction	10
E2F1 promotes cell migration in hepatocellular carcinoma via FNDC3B	10
Issue Information	10
Liraglutide enhances the effect of checkpoint blockade in lung and liver cancers through the inhibition of neutrophil extracellular traps	10
Guaiazulene derivative 1,2,3,4‐tetrahydroazuleno[1,2‐b] tropone reduces the production of ATP by inhibiting electron transfer complex II	9
Environmental pH stress influences cellular secretion and uptake of extracellular vesicles	9
Identification of two methylated fragments of an SDC2 CpG island using a sliding window technique for early detection of colorectal cancer	9
The durability of resin–dentine bonds are enhanced by epigallocatechin‐3‐gallate‐encapsulated nanohydroxyapatite/mesoporous silica	9
Thermodynamic analysis of the interactions between human ACE2 and spike RBD of Betacoronaviruses (SARS‐CoV‐1 and SARS‐CoV‐2)	9
2‐dodecyl‐6‐methoxycyclohexa‐2,5‐diene‐1,4‐dione mediates the effect of ROS‐enhanced PI3K/Akt/mTOR pathway on autophagy in breast cancer	9
Ets family proteins regulate the EMT transcription factors Snail and ZEB in cancer cells	9
The beginning and the end of SNARE‐induced membrane fusion	9
N6‐methyladenosine (m6A) RNA modification of G protein‐coupled receptor 133 increases proliferation of lung adenocarcinoma	9
Urinary SPP1 has potential as a non‐invasive diagnostic marker for focal segmental glomerulosclerosis	9
Cost‐effective and simple flow cytometry quantification of receptor‐mediated autophagy using fluorescent tagging	9
Analgesic effects of nerve growth factor‐directed monoclonal antibody on diabetic neuralgia in an animal model	9
Bone marrow mesenchymal stem cell‐derived extracellular vesicles promote corneal epithelial repair and suppress apoptosis via modulation of Caspase‐3 in vitro	9
Dysbiosis of gut microbiota after cholecystectomy is associated with non‐alcoholic fatty liver disease in mice	9
Chorein deficiency promotes ferroptosis	8
GPR35‐mediated kynurenic acid sensing contributes to maintenance of gut microbiota homeostasis in ulcerative colitis	8
Immune‐related matrisomes are potential biomarkers to predict the prognosis and immune microenvironment of glioma patients	8
Issue Information	8
Characterization of the complete chloroplast genome of Rhodiola sachalinensis and comparative analysis with its congeneric plants	8
Down‐regulation of Polo‐like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer	8
Interaction of RECQL4 with poly(ADP‐ribose) is critical for the DNA double‐strand break response in human cells	8
Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteins	8
Teaching, research or balanced? An exploration of the experiences of biomedical scientists working in UK medical schools	8
CDK5 interacts with MST2 and modulates the Hippo signalling pathway	8
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Membrane‐acting biomimetic peptoids against visceral leishmaniasis	8
Optogenetic control of early embryos labeling using photoactivatable Cre recombinase 3.0	8
Carbohydrate response element‐binding protein (ChREBP) mediates decreased SNAP25 expression in islets from diabetic Goto‐Kakizaki (GK) rats	8
Anti‐inflammatory properties of ophioglonin derived from the fern Ophioglossum vulgatum L. via inactivating NF‐κB and MAPK signaling pathways	8
Downregulation of SUMO2 inhibits hepatocellular carcinoma cell proliferation, migration and invasion	8
Mutations in RPS19 may affect ribosome function and biogenesis in Diamond Blackfan anemia	8
Molecular dynamics provides new insights into the mechanism of calcium signal transduction and interdomain interactions in cardiac troponin	8
Transcriptional changes impact hepatic proteome in autophagy‐impaired liver	8
Biochemical characterization of a novel oxidatively stable, halotolerant, and high‐alkaline subtilisin from Alkalihalobacillus okhensisKh10‐101T	8
Making teamwork work: enhancing teamwork and assessment in higher education	8
Expansion Microscopy‐based imaging for visualization of mitochondria in Drosophila ovarian germline stem cells	7
Correction	7
The breast cancer microenvironment and lipoprotein lipase: Another negative notch for a beneficial enzyme?	7
DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms	7
RETRACTION: XBP1 Inhibits Mesangial Cell Apoptosis in Response to Oxidative Stress via the PTEN/AKT Pathway in Diabetic Nephropathy	7
Potential radiosensitive germline biomarkers in the testes of wild mice after the Fukushima accident	7
RETRACTION: LKB1 Suppresses Androgen Synthesis in a Mouse Model of Hyperandrogenism via IGF‐1 Signaling	7
Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold	7
4,5,7‐Trisubstituted indeno[1,2‐b]indole inhibits CK2 activity in tumor cells equivalent to CX‐4945 and shows strong anti‐migratory effects	7
SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer	7
A curcumin analogue GO‐Y030 depletes cancer stem cells by inhibiting the interaction between the HSP70/HSP40 complex and its substrates	7
HIF2α‐induced upregulation of RNASET2 promotes triglyceride synthesis and enhances cell migration in clear cell renal cell carcinoma	7
Development of a variant of dinutuximab with enhanced antitumor efficacy and reduced induction of neuropathic pain	7
Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation	7
Characterization of two bacterial tyrosinases from the halophilic bacterium Hahella sp. CCB MM4 relevant for phenolic compounds oxidation in wetlands	7

Retraction statement: Ding, J., Wang, X., Gao, J. and Song, T. (2021), Silencing of cystatin SN abrogates cancer progression and stem cell properties in papillary thyroid carcinoma. FEBS Open Bio, 11:	7
Apolipoprotein M promotes cholesterol uptake and efflux from mouse macrophages	7
CCR4‐IL2 bispecific immunotoxin is more effective than brentuximab for targeted therapy of cutaneous T‐cell lymphoma in a mouse CTCL model	7
c‐Abl kinase regulates cell proliferation and ionizing radiation‐induced G2/M arrest via phosphorylation of FHL2	7
Large‐scale analysis of the genome of the rare alkaline‐halophilic Stachybotrys microspora reveals 46 cellulase genes	7
Professor Stuart John Ferguson (29 September 1949–25 April 2024)	7
Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition	7
Withdrawn: MicroRNA‐142‐5p inhibits autophagy in cardiomyocytes in a mouse model of hypoxia/reoxygenation	7
PRMT1‐mediated arginine methylation promotes YAP activation and hepatocellular carcinoma proliferation	7
Antitubercular potential and pH‐driven mode of action of salicylic acid derivatives	7
The relationship between depletion of brain GM1 ganglioside and Parkinson's disease	7
Identification of novel meQTLs strongly associated with rheumatoid arthritis by large‐scale epigenome‐wide analysis	6
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation	6
Myoblast‐derived exosomes promote the repair and regeneration of injured skeletal muscle in mice	6
Viral and cellular translation during SARS‐CoV‐2 infection	6
Delta‐9 desaturase reduction in gastrointestinal cells induced to senescence by doxorubicin	6
Nanobody engineering: computational modelling and design for biomedical and therapeutic applications	6
Nanoparticles of folic acid‐methyl‐β‐cyclodextrin (FA‐MβCD)/adamantane‐albumin exhibit enhanced antitumor activity compared with FA‐MβCD alone	6
Expression of a Crry/p65 is reduced in acute lung injury induced by extracellular histones	6
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Development and validation of a four‐lipid metabolism gene signature for diagnosis of pancreatic cancer	6
Characterization of the preferred cation cofactors of chloroplast protein kinases in Arabidopsis thaliana	6
Characterization of the promoter region of the murine Catsper2 gene	6
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Prognostic biomarker identification and tumor classification in breast cancer patients by methylation and transcriptome analysis	6
Expression of a triple mutational des‐pGlu brazzein in transgenic mouse milk	6
Multiple interaction modes between saccharin and sweet taste receptors determine a species‐dependent response to saccharin	6
Destabilization of vitelline membrane outer layer protein 1 homolog (VMO1) by C‐mannosylation	6
Signature reversion of three disease‐associated gene signatures prioritizes cancer drug repurposing candidates	6
Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast	6
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SV40 T antigen helicase domain regions responsible for oligomerisation regulate Okazaki fragment synthesis initiation	6
Tim‐3 suppresses autoimmune hepatitis via the p38/MKP‐1 pathway in Th17 cells	6
Viral entry mechanisms: the role of molecular simulation in unlocking a key step in viral infections	6
Integrative computational approach identifies immune‐relevant biomarkers in ulcerative colitis	6
Serum metabolomics detected by LDI‐TOF‐MS can be used to distinguish between diabetic patients with and without diabetic kidney disease	6
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction	6
Science students' perspectives on how to decrease the stigma of failure	6
Small ankyrin 1 (sANK1) promotes docetaxel resistance in castration‐resistant prostate cancer cells by enhancing oxidative phosphorylation	6
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response	6
Cordycepin inhibits cell senescence by ameliorating lysosomal dysfunction and inducing autophagy through the AMPK and mTOR–p70S6K pathway	6
Characterization and comparison of recombinant full‐length ursine and human sex hormone‐binding globulin	6
Machine learning‐mediated identification of ferroptosis‐related genes in osteonecrosis of the femoral head	6
Transfer of stabilising mutations between different secondary active transporter families	6
Functional characterization of all‐trans retinoic acid‐induced differentiation factor (ATRAID)	5
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4	5
Nanoscale‐tipped wire array injections transfer DNA directly into brain cells ex vivo and in vivo	5
Screening and characterization of aptamers recognizing the periodontal pathogen Tannerella forsythia	5
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Dysfunction of Drosophila mitochondrial carrier homolog (Mtch) alters apoptosis and disturbs development	5
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Nicotinamide mononucleotide (NMN) protects bEnd.3 cells against H2O2‐induced damage via NAMPT and the NF‐κB p65 signalling pathway	5
Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish	5
Cantharidin downregulates PSD1 expression and inhibits autophagic flux in yeast cells	5
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Issue Information	5
High growth hormone serum partially protects mice against Trypanosoma cruzi infection	5
Short‐term exposure to ethanol induces transcriptional changes in nontumorigenic breast cells	5
Biochemical characterization and gene structure analysis of the 24‐kDa glutathione transferase sigma from Taenia solium	5
Front Cover	5
Evolution of memory system‐related genes	5
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Dkk1 inhibits malignant transformation induced by Bmi1 via the β‐catenin signaling axis in WB‐F344 oval cells	5
Talks	5
PAPP‐A functions as a tumor suppressor and is downregulated in renal cell carcinoma	5
Withdrawal: Urinary exosomal tRNA‐derived small RNA signatures as a predictive biomarker in lung cancer	5
ERCC5, HES6 and RORA are potential diagnostic markers of coronary artery disease	5
Fibroblast growth factor 2 acts as an upstream regulator of inhibition of pulmonary fibroblast activation	5
Structural information in therapeutic peptides: Emerging applications in biomedicine	5
Development of a mouse embryonic stem cell model for investigating the functions of the linker histone H1‐4	5
The intracellular helical bundle of human glucose transporter GLUT4 is important for complex formation with ASPL	5
Issue Information	5
Issue Information	5
Issue Information	5
Seasonal UV exposure and vitamin D: association with the dynamics of COVID‐19 transmission in Europe	5
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Overexpression of TRAF4 promotes lung cancer growth and EGFR‐dependent phosphorylation of ERK5	5
Structural investigations of proteins encoded by SARS‐CoV‐2	5
Novel insights into brain lipid metabolism in Alzheimer's disease: Oligodendrocytes and white matter abnormalities	5
Potentially reduced fusogenicity of syncytin‐2 in New World monkeys	5
Identification of differentially expressed genes in diabetic kidney disease by RNA‐Seq analysis of venous blood platelets	5
Zebrafish and medaka T1R (taste receptor type 1) proteins mediate highly sensitive recognition of l‐proline	5
Follicle‐stimulating hormone worsens osteoarthritis by causing inflammation and chondrocyte dedifferentiation	4
KIF2C affects sperm cell differentiation in patients with Klinefelter syndrome, as revealed by RNA‐Seq and scRNA‐Seq data	4
Frequency, topic, and preferences: Tracking student engagement with several modalities of student–instructor contact in a first‐year course	4
An outlook on structural biology after AlphaFold: tools, limits and perspectives	4
Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase‐related protein via different regions	4
MTHFD2 promotes ovarian cancer growth and metastasis via activation of the STAT3 signaling pathway	4
Cabazitaxel suppresses colorectal cancer cell growth via enhancing the p53 antitumor pathway	4
Crystal structure of a novel homodimeric l‐ribulose 3‐epimerase from Methylomonus sp.	4
Lactate administration does not affect denervation‐induced loss of mitochondrial content and muscle mass in mice	4
Pin1 and JNK1 cooperatively modulate TAp63γ	4
The miR‐223/nuclear factor I‐A axis regulates inflammation and cellular functions in intestinal tissues with necrotizing enterocolitis	4
Development and single‐particle analysis of hybrid extracellular vesicles fused with liposomes using viral fusogenic proteins	4
Novel circular RNAs of the apoptosis‐related BAX and BCL2L12 genes identified in a chronic lymphocytic leukemia cell line using nanopore sequencing	4