OOIR: Observatory of International Research

Papers

(The TQCC of International Journal for Parasitology-Drugs and Drug Resistance is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Combining the zebrafish embryo developmental toxicity assay (ZEDTA) with hemoglobin staining to accelerate the research of novel antimalarial drugs for pregnant women	78
Antiamoeboid activity of squamins C–F, cyclooctapeptides from Annona globifora	73
Chicory (Cichorium intybus) reduces cyathostomin egg excretion and larval development in grazing horses	67
Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites	63
Effects of the G-quadruplex-binding drugs quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum	58
Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife	52
Development of a three-colour digital PCR for early and quantitative detection of benzimidazole resistance-associated single nucleotide polymorphisms in Haemonchus contortus	50
Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage	46
Efficacy of fenbendazole against gastrointestinal nematodes in naturally infected goats in Maputo Province, Mozambique using in vivo, in vitro and molecular assessment	37
MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission	33
Nourseothricin as a novel drug for selection of transgenic Giardia lamblia	30
In vitro evaluation of new 4-thiazolidinones on invasion and growth of Toxoplasma gondii	25
Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides	22
Plasmodium RNA triphosphatase validation as antimalarial target	22
Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook	22
Modified dosing schedule efficacy of fosmidomycin and clindamycin against murine malaria Plasmodium berghei	22
The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei	21
Suramin action in African trypanosomes involves a RuvB-like DNA helicase	21
Acaricide resistance status of livestock ticks from East and West Africa and in vivo efficacy of acaricides to control them	21
A review study on the anti-trichomonas activities of medicinal plants	20
Phenotypic and genotypic characterization of acaricide resistance in Rhipicephalus microplus field isolates from South Africa and Brazil	18
Current and emerging target identification methods for novel antimalarials	18
Exploring the β-tubulin gene family in a benzimidazole-resistant Parascaris univalens population	17
Antiplasmodial activity of the natural product compounds alstonine and himbeline	17
Monepantel pharmaco-therapeutic evaluation in cattle: Pattern of efficacy against multidrug resistant nematodes	17

Phenotypic and genotypic analysis of benzimidazole resistance in reciprocal genetic crosses of Haemonchus contortus	17
Reflecting on the past and fast forwarding to present day anthelmintic resistant Ancylostoma caninum–A critical issue we neglected to forecast	16
Comparative structure activity and target exploration of 1,2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans	16
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice	16
Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population	16
Repurposing DrugBank compounds as potential Plasmodium falciparum class 1a aminoacyl tRNA synthetase multi-stage pan-inhibitors with a specific focus on mitomycin	16
Natural marine products as antiprotozoal agents against amitochondrial parasites	15
Recent in vitro advances in the ocular antimicrobial agents against Acanthamoeba	14
Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations	13
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia	13
Rational approach to drug discovery for human schistosomiasis	13
In vitro validation of the amoebicidal activity of commercial eye drops as second activity	13
Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization	13
Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates	13
In vitro and in vivo activity evaluation and mode of action of broxaldine on Toxoplasma gondii	12
Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile	11
In vitro amoebicidal effects of arabinogalactan-based ophthalmic solution	11
Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation	11
Dissection of haplotype-specific drug response phenotypes in multiclonal malaria isolates	11
In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii	10
Acrylonitrile derivatives: In vitro activity and mechanism of cell death induction against Trypanosoma cruzi and Leishmania amazonensis	10
In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast	10
Evaluation of the antiplasmodial efficacy of synthetic 2,5-diphenyloxazole analogs of compounds naturally derived from Oxytropis lanata	10
Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonensis	10
Diethylcarbamazine mediated potentiation of emodepside induced paralysis requires TRP-2 in adult Brugia malayi	9
Using droplet digital PCR for the detection of hco-acr-8b levamisole resistance marker in H. contortus	9
Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum	9
Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans	9
Lactoferrin-modified nanoemulsions enhance brain-targeting and therapeutic efficacy of arctigenin against Toxoplasma gondii-induced neuronal injury	9