OOIR: Observatory of International Research

Papers

(The median citation count of International Journal for Parasitology-Drugs and Drug Resistance is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Heartworm disease – Overview, intervention, and industry perspective	64
A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa	60
Where are all the anthelmintics? Challenges and opportunities on the path to new anthelmintics	58
Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles	51
Anthelmintic resistance in equine nematodes: Current status and emerging trends	50
Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook	50
Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance	49
Caenorhabditis elegans in anthelmintic research – Old model, new perspectives	49
Artemisinin-based combination therapy (ACT) and drug resistance molecular markers: A systematic review of clinical studies from two malaria endemic regions – India and sub-Saharan Africa	49
The molecular basis of antimalarial drug resistance in Plasmodium vivax	46
Importation of macrocyclic lactone resistant cyathostomins on a US thoroughbred farm	45
Multiple drug resistance in hookworms infecting greyhound dogs in the USA	38
Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions	36
Praziquantel use in aquaculture – Current status and emerging issues	32
The use of ITS-2 rDNA nemabiome metabarcoding to enhance anthelmintic resistance diagnosis and surveillance of ovine gastrointestinal nematodes	30
Spread of anthelmintic resistance in intestinal helminths of dogs and cats is currently less pronounced than in ruminants and horses – Yet it is of major concern	28
Focused review: The role of drug combinations for the control of coccidiosis in commercially reared chickens	25
Newly identified parasitic nematode beta-tubulin alleles confer resistance to benzimidazoles	25
Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation	21
HDAC inhibitors Tubastatin A and SAHA affect parasite cell division and are potential anti-Toxoplasma gondii chemotherapeutics	20
Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations	20
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma	20
A review study on the anti-trichomonas activities of medicinal plants	20
Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens	20
A new paraprobiotic-based treatment for control of Haemonchus contortus in sheep	19

Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018	17
Treatment of human intestinal cryptosporidiosis: A review of published clinical trials	17
In vitro and in vivo anti-Cryptosporidium and anti-inflammatory effects of Aloe vera gel in dexamethasone immunosuppressed mice	16
The first report of macrocyclic lactone resistant cyathostomins in the UK	16
Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited	16
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside	16
Current and emerging target identification methods for novel antimalarials	16
Repurposing bioenergetic modulators against protozoan parasites responsible for tropical diseases	15
Exploring the β-tubulin gene family in a benzimidazole-resistant Parascaris univalens population	15
Natural variation in Caenorhabditis elegans responses to the anthelmintic emodepside	15
Reflecting on the past and fast forwarding to present day anthelmintic resistant Ancylostoma caninum–A critical issue we neglected to forecast	15
Mefloquine as a prophylaxis for malaria needs to be revisited	14
Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population	14
Advances in our understanding of nematode ion channels as potential anthelmintic targets	13
Evaluation of the therapeutic efficacy of praziquantel against schistosomes in seven countries with ongoing large-scale deworming programs	13
Nucleoside analogues for the treatment of animal trypanosomiasis	13
The ultimate fate determinants of drug induced cell-death mechanisms in Trypanosomatids	13
Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters	12
Antiplasmodial activity of the natural product compounds alstonine and himbeline	12
In vitro evaluation of new 4-thiazolidinones on invasion and growth of Toxoplasma gondii	11
Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthelmintic resistance on	11
Climate change is likely to increase the development rate of anthelmintic resistance in equine cyathostomins in New Zealand	11
Using droplet digital PCR for the detection of hco-acr-8b levamisole resistance marker in H. contortus	11
Rational approach to drug discovery for human schistosomiasis	11
Activity of paromomycin against Leishmania amazonensis: Direct correlation between susceptibility in vitro and the treatment outcome in vivo	11
Nullscript inhibits Cryptosporidium and Toxoplasma growth	11
Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus	10
Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum	10
Dicyclanil resistance in the Australian sheep blowfly, Lucilia cuprina, substantially reduces flystrike protection by dicyclanil and cyromazine based products	10
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo	9
Anti-protozoal activity of Thymol and a Thymol ester against Cryptosporidium parvum in cell culture	9
A retrospective cohort study of the effectiveness and adverse events of intralesional pentavalent antimonials in the treatment of cutaneous leishmaniasis	9
Sterol profiling of Leishmania parasites using a new HPLC-tandem mass spectrometry-based method and antifungal azoles as chemical probes reveals a key intermediate sterol that supports a branched ergo	9
Copper detoxification machinery of the brain-eating amoeba Naegleria fowleri involves copper-translocating ATPase and the antioxidant system	9
Novel flavanones with anti-trypanosomal activity isolated from Zambian and Tanzanian propolis samples	9
Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross	9
Route of administration influences the concentration of ivermectin reaching nematode parasites in the gastrointestinal tract of cattle	9
Antileishmanial activity of a new chloroquine analog in an animal model of Leishmania panamensis infection	8
Apparent treatment failure of praziquantel and pyrantel pamoate against anoplocephalid tapeworms	8
Molecular characterization and analysis of the ATPase ASNA1 homolog gene of Eimeria tenella in a drug sensitive strain and drug resistant strains	8
TriTOX: A novel Trichomonas vaginalis assay platform for high-throughput screening of compound libraries	7
Ascaridia galli - An old problem that requires new solutions	7
Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile	7
In vitro selection of Giardia duodenalis for Albendazole resistance identifies a β-tubulin mutation at amino acid E198K	7
Benzimidazole F167Y polymorphism in the canine hookworm, Ancylostoma caninum: Widespread geographic, seasonal, age, and breed distribution in United States and Canada dogs	7
Rapid determination of nematode cell and organ susceptibility to toxic treatments	7
Ex vivo susceptibility to new antimalarial agents differs among human-infecting Plasmodium species	7
3-nitroimidazo[1,2-b]pyridazine as a novel scaffold for antiparasitics with sub-nanomolar anti-Giardia lamblia activity	7
Thiophene derivatives activity against the protozoan parasite Leishmania infantum	7
Antiamoeboid activity of squamins C–F, cyclooctapeptides from Annona globifora	7

Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans	6
Transdermal delivery of artemisinins for treatment of pre-clinical cerebral malaria	6
6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents	6
A conserved coccidian gene is involved in Toxoplasma sensitivity to the anti-apicomplexan compound, tartrolon E	6
Nicotinic acetylcholine receptors in the synganglion of the tick Ixodes ricinus: Functional characterization using membrane microtransplantation	6
The presence and relative frequency detection of the levamisole-resistance-associated S168T substitution in hco-acr-8 in Haemonchus contortus	6
A short-term treatment with BKI-1294 does not protect foetuses from sheep experimentally infected with Neospora caninum tachyzoites during pregnancy	6
Identification of lobetyolin as a major antimalarial constituent of the roots of Lobelia giberroa Hemsl	6
RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development	5
Poor adherence is a major barrier to the proper treatment of cutaneous leishmaniasis: A case-control field assessment in Iran	5
In vitro evaluation of Resveratrol as a potential pre-exposure prophylactic drug against Trypanosoma cruzi infection	5
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia	5
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice	5
Novel acyl carbamates and acyl / diacyl ureas show in vitro efficacy against Toxoplasma gondii and Cryptosporidium parvum	5
In vitro activity and mechanism of cell death induction of cyanomethyl vinyl ethers derivatives against Trypanosoma cruzi	5
Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation	5
In vitro evaluation of commercial foam Belcils® on Acanthamoeba spp	5
Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife	5
Exploration of the sensitivity to macrocyclic lactones in the canine heartworm (Dirofilaria immitis) in Australia using phenotypic and genotypic approaches	5
MMV560185 from pathogen box induces extrinsic pathway of apoptosis in Theileria annulata infected bovine leucocytes	5
Forward genetic analysis of monensin and diclazuril resistance in Eimeria tenella	5
Phenotypic and genotypic analysis of benzimidazole resistance in reciprocal genetic crosses of Haemonchus contortus	5
Physiological and proteomic profiles of Trypanosoma brucei rhodesiense parasite isolated from suramin responsive and non-responsive HAT patients in Busoga, Uganda	4
Effect of geranylated dihydrochalcone from Artocarpus altilis leaves extract on Plasmodium falciparum ultrastructural changes and mitochondrial malate: Quinone oxidoreductase	4
Inhibitory effect of morin on aldolase 2 from Eimeria tenella	4
Diethylcarbamazine mediated potentiation of emodepside induced paralysis requires TRP-2 in adult Brugia malayi	4
Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage	4
Phosphatase inhibitors BVT-948 and alexidine dihydrochloride inhibit sexual development of the malaria parasite Plasmodium berghei	4
Detection of target-site and metabolic resistance to pyrethroids in the bed bug Cimex lectularius in Berlin, Germany	4
Genetic characterisation of the Theileria annulata cytochrome b locus and its impact on buparvaquone resistance in bovine	4
Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization	4
Natural marine products as antiprotozoal agents against amitochondrial parasites	4
Genomic analysis of Indian isolates of Plasmodium falciparum: Implications for drug resistance and virulence factors	4
Longitudinal ex vivo and molecular trends of chloroquine and piperaquine activity against Plasmodium falciparum and P. vivax before and after introduction of artemisinin-based combination therapy in P	4
New diarylsulfonamide inhibitors of Leishmania infantum amastigotes	4
Molecular characterization and analysis of drug resistance-associated protein enolase 2 of Eimeria tenella	4
Development of a three-colour digital PCR for early and quantitative detection of benzimidazole resistance-associated single nucleotide polymorphisms in Haemonchus contortus	4