OOIR: Observatory of International Research

Papers

(The median citation count of International Journal for Parasitology-Drugs and Drug Resistance is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Pharmacokinetic and pharmacodynamic considerations for treating sarcoptic mange with cross-relevance to Australian wildlife	64
Chicory (Cichorium intybus) reduces cyathostomin egg excretion and larval development in grazing horses	60
Screening of the activity of sixty essential oils against plasmodium early mosquito stages in vitro and machine learning analysis reveals new putative inhibitors of malaria parasites	50
Monepantel pharmaco-therapeutic evaluation in cattle: Pattern of efficacy against multidrug resistant nematodes	50
In vivo efficiency of praziquantel treatment of single-sex Schistosoma japonicum aged three months old in mice	49
MEFAS, a hybrid of artesunate-mefloquine active against asexual stages of Plasmodium vivax in field isolates, inhibits malaria transmission	49
Natural marine products as antiprotozoal agents against amitochondrial parasites	42
Effects of the G-quadruplex-binding drugs quarfloxin and CX-5461 on the malaria parasite Plasmodium falciparum	38
Plasmodium RNA triphosphatase validation as antimalarial target	34
Nourseothricin as a novel drug for selection of transgenic Giardia lamblia	28
Repurposing DrugBank compounds as potential Plasmodium falciparum class 1a aminoacyl tRNA synthetase multi-stage pan-inhibitors with a specific focus on mitomycin	28
Comparative structure activity and target exploration of 1,2-diphenylethynes in Haemonchus contortus and Caenorhabditis elegans	25
Discovery of antiplasmodial pyridine carboxamides and thiocarboxamides	21
In vitro evaluation of new 4-thiazolidinones on invasion and growth of Toxoplasma gondii	20
Phenotypic and genotypic characterization of acaricide resistance in Rhipicephalus microplus field isolates from South Africa and Brazil	20
Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage	20
Antiamoeboid activity of squamins C–F, cyclooctapeptides from Annona globifora	20
A review study on the anti-trichomonas activities of medicinal plants	17
Antiplasmodial activity of the natural product compounds alstonine and himbeline	17
Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population	17
Exploring the β-tubulin gene family in a benzimidazole-resistant Parascaris univalens population	16
Phenotypic and genotypic analysis of benzimidazole resistance in reciprocal genetic crosses of Haemonchus contortus	16
Plasmodium falciparum resistance to ACTs: Emergence, mechanisms, and outlook	16
Current and emerging target identification methods for novel antimalarials	16
Suramin action in African trypanosomes involves a RuvB-like DNA helicase	16

Development of a three-colour digital PCR for early and quantitative detection of benzimidazole resistance-associated single nucleotide polymorphisms in Haemonchus contortus	15
Reflecting on the past and fast forwarding to present day anthelmintic resistant Ancylostoma caninum–A critical issue we neglected to forecast	15
The phosphatase inhibitor BVT-948 can be used to efficiently screen functional sexual development proteins in the malaria parasite Plasmodium berghei	14
Acaricide resistance status of livestock ticks from East and West Africa and in vivo efficacy of acaricides to control them	14
In vitro amoebicidal effects of arabinogalactan-based ophthalmic solution	13
Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations	13
Evaluation of the antiplasmodial efficacy of synthetic 2,5-diphenyloxazole analogs of compounds naturally derived from Oxytropis lanata	13
In vitro and in vivo activity evaluation and mode of action of broxaldine on Toxoplasma gondii	12
In vitro and in vivo activities of a trithiolato-diRuthenium complex conjugated with sulfadoxine against the apicomplexan parasite Toxoplasma gondii	12
Characterization of a P-glycoprotein drug transporter from Toxocara canis with a novel pharmacological profile	11
Integration of population and functional genomics to understand mechanisms of artemisinin resistance in Plasmodium falciparum	11
Diethylcarbamazine mediated potentiation of emodepside induced paralysis requires TRP-2 in adult Brugia malayi	11
In artemisinin-resistant falciparum malaria parasites, mitochondrial metabolic pathways are essential for survival but not those of apicoplast	11
Stepwise in vitro screening of MMV pathogen box compounds against Plasmodium falciparum to identify potent antimalarial candidates	10
Corrigendum to “Efficacy of flukicides against Fasciola hepatica and first report of triclabendazole resistance on German sheep farms” [Int. J. Parasitol. Drugs Drug Resist. 23 (2023) 94–105]	10
Filarial nematode phenotypic screening cascade to identify compounds with anti-parasitic activity for drug discovery optimization	9
Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia	9
Acrylonitrile derivatives: In vitro activity and mechanism of cell death induction against Trypanosoma cruzi and Leishmania amazonensis	9
In vitro validation of the amoebicidal activity of commercial eye drops as second activity	9
Egg reappearance periods of anthelmintics against equine cyathostomins: The state of play revisited	8
Primaquine for Plasmodium vivax radical cure: What we do not know and why it matters	8
Using droplet digital PCR for the detection of hco-acr-8b levamisole resistance marker in H. contortus	7
Proteomic characterization of Toxoplasma gondii ME49 derived strains resistant to the artemisinin derivatives artemiside and artemisone implies potential mode of action independent of ROS formation	7
Comparison of electrophysiological and motility assays to study anthelmintic effects in Caenorhabditis elegans	7
Allele specific PCR for a major marker of levamisole resistance in Haemonchus contortus	7
The presence and relative frequency detection of the levamisole-resistance-associated S168T substitution in hco-acr-8 in Haemonchus contortus	7
Forward genetic analysis of monensin and diclazuril resistance in Eimeria tenella	7
Efficacy of the treatment using a microemulsion loaded with epoxy-α-lapachone in combination with meglumine antimoniate against murine infection by Leishmania (Leishmania) amazonensis	7
Dissection of haplotype-specific drug response phenotypes in multiclonal malaria isolates	7
In vitro and in vivo anti-Cryptosporidium and anti-inflammatory effects of Aloe vera gel in dexamethasone immunosuppressed mice	6
Benzimidazole F167Y polymorphism in the canine hookworm, Ancylostoma caninum: Widespread geographic, seasonal, age, and breed distribution in United States and Canada dogs	6
Heartworm disease – Overview, intervention, and industry perspective	6
Erratum to “Uncovering the antimalarial potential of toad venoms through a bioassay-guided fractionation process” [Int. J. Parasitol.: Drugs Drug Resist. 20 (2022) 97–107]	6
Thiophene derivatives activity against the protozoan parasite Leishmania infantum	6
Rational approach to drug discovery for human schistosomiasis	6
Anthelmintic resistance in equine nematodes: Current status and emerging trends	6
Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity	5
Treatment of human intestinal cryptosporidiosis: A review of published clinical trials	5
Demonstration of reduced efficacy against cyathostomins without change in species composition after pyrantel embonate treatment in Swedish equine establishments	5
Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018	5
Artemisinin-based combination therapy (ACT) and drug resistance molecular markers: A systematic review of clinical studies from two malaria endemic regions – India and sub-Saharan Africa	5
The molecular basis of antimalarial drug resistance in Plasmodium vivax	5
Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues	5
Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside	5
Selenosugars targeting the infective stage of Trypanosoma brucei with high selectivity	5
Revisiting anthelmintic resistance in sheep flocks from São Paulo State, Brazil	5
Treating cryptosporidiosis: A review on drug discovery strategies	5
Increased copy number of the target gene squalene monooxygenase as the main resistance mechanism to terbinafine in Leishmania infantum	5
Exploring therapeutic approaches against Naegleria fowleri infections through the COVID box	4
Activity of (1-benzyl-4-triazolyl)-indole-2-carboxamides against Toxoplasma gondii and Cryptosporidium parvum	4

The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children	4
The therapeutic potential of novel isobenzofuranones against Naegleria fowleri	4
Absence of association between Pfnfs1 mutation and in vitro susceptibility to lumefantrine in Plasmodium falciparum	4
Identification of compounds responsible for the anthelmintic effects of chicory (Cichorium intybus) by molecular networking and bio-guided fractionation	4
Repurposing in vitro approaches for screening anti-parasitic drugs against the brain-eating amoeba Naegleria fowleri	4
Molecular characterization and analysis of the ATPase ASNA1 homolog gene of Eimeria tenella in a drug sensitive strain and drug resistant strains	4
Thieno[3,2-b]pyrrole 5-carboxamides as potent and selective inhibitors of Giardia duodenalis	4
Molecular characterization and analysis of drug resistance-associated protein enolase 2 of Eimeria tenella	4
In vitro evaluation of Resveratrol as a potential pre-exposure prophylactic drug against Trypanosoma cruzi infection	4
Histone deacetylase inhibitor AR-42 and achiral analogues kill malaria parasites in vitro and in mice	4
Potent and selective antiplasmodial activity of marine sponges from Bahia state, Brazil	4
Modified peptides and organic metabolites of cyanobacterial origin with antiplasmodial properties	4
Inhibitory effect of morin on aldolase 2 from Eimeria tenella	3
Droplet digital PCR as a tool to detect resistant isolates of Dirofilaria immitis	3
Uncovering the antimalarial potential of toad venoms through a bioassay-guided fractionation process	3
The first report of macrocyclic lactone resistant cyathostomins in the UK	3
Transcriptomic analysis of albendazole resistance in human diarrheal parasite Giardia duodenalis	3
Profile of molecular markers of Sulfadoxine-Pyrimethamine-resistant Plasmodium falciparum in individuals living in southern area of Brazzaville, Republic of Congo	3
Evaluation of changes in drug susceptibility and population genetic structure in Haemonchus contortus following worm replacement as a means to reverse the impact of multiple-anthelmintic resistance on	3
Deep-amplicon sequencing of the complete beta-tubulin gene in Trichuris trichiura before and after albendazole treatment	3
Genetic characterisation of the Theileria annulata cytochrome b locus and its impact on buparvaquone resistance in bovine	3
In vivo efficacy of pyrantel pamoate as a post-exposure prophylactic for rat lungworm (Angiostrongylus cantonensis)	3
Identification of new drug candidates against Trichomonas gallinae using high-throughput screening	3
Phylogenetic and transcriptomic study of aldo-keto reductases in Haemonchus contortus and their inducibility by flubendazole	3
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma	3
Antileishmanial and synergic effects of Rhanterium epapposum essential oil and its main compounds alone and combined with glucantime against Leishmania major infection	3
Anti-parasitic benzoxaboroles are ineffective against Theileria parva in vitro	3
Investigation of risk factors associated with Ancylostoma spp. infection and the benzimidazole F167Y resistance marker polymorphism in dogs from the United States	3
Effect of the pseudomonas metabolites HQNO on the Toxoplasma gondii RH strain in vitro and in vivo	3
The Haemonchus contortus LGC-39 subunit is a novel subtype of an acetylcholine-gated chloride channel	3