OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Reports is 90. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients	601
Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7	350
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells	301
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants	293
D614G Mutation Alters SARS-CoV-2 Spike Conformation and Enhances Protease Cleavage at the S1/S2 Junction	263
The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity	248
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications	224
ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis	204
Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH	203
Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities	192
BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils	189
SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO	188
The effect of spike mutations on SARS-CoV-2 neutralization	182
Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution	181
ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism	177
SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination	174
Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant	171
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery	168
Lactate Limits T Cell Proliferation via the NAD(H) Redox State	168
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2	166
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms	163
METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection	159
Targeting TREM2 on tumor-associated macrophages enhances immunotherapy	158
Systemic IL-15, IFN-γ, and IP-10/CXCL10 signature associated with effective immune response to SARS-CoV-2 in BNT162b2 mRNA vaccine recipients	157
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans	154

Protein lactylation induced by neural excitation	147
Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology	142
Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer	140
Cancer Stemness Meets Immunity: From Mechanism to Therapy	140
Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells	139
Anipose: A toolkit for robust markerless 3D pose estimation	138
Most non-canonical proteins uniquely populate the proteome or immunopeptidome	134
Itaconate confers tolerance to late NLRP3 inflammasome activation	134
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis	132
Linear epitope landscape of the SARS-CoV-2 Spike protein constructed from 1,051 COVID-19 patients	131
Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study	129
Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells	129
Tumor metabolite lactate promotes tumorigenesis by modulating MOESIN lactylation and enhancing TGF-β signaling in regulatory T cells	124
Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors	124
The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance	122
Mechanical Stiffness Controls Dendritic Cell Metabolism and Function	122
Establishment of a reverse genetics system for SARS-CoV-2 using circular polymerase extension reaction	121
Small Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate	119
Dietary spermidine improves cognitive function	117
A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters	116
Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD	116
Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer	115
Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering	114
Homocysteine inhibits pro-insulin receptor cleavage and causes insulin resistance via protein cysteine-homocysteinylation	113
Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2	113
Rapid Precision Functional Mapping of Individuals Using Multi-Echo fMRI	113
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell	112
Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice	112
Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies	112
A compact vocabulary of paratope-epitope interactions enables predictability of antibody-antigen binding	111
IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease	110
Structural and functional impact by SARS-CoV-2 Omicron spike mutations	110
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity	109
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution	108
Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts	107
Unified classification of mouse retinal ganglion cells using function, morphology, and gene expression	106
High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity	106
Distinct biological ages of organs and systems identified from a multi-omics study	105
Tethering Piezo channels to the actin cytoskeleton for mechanogating via the cadherin-β-catenin mechanotransduction complex	105
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex	105
Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia	104
Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments	102
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice	102
The Cancer SENESCopedia: A delineation of cancer cell senescence	102
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern	102
TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis	99
Efficient stimulation of retinal regeneration from Müller glia in adult mice using combinations of proneural bHLH transcription factors	99
Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients	98
Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects	98
Metabolic programs define dysfunctional immune responses in severe COVID-19 patients	97

Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation	97
Inflammasomes within Hyperactive Murine Dendritic Cells Stimulate Long-Lived T Cell-Mediated Anti-tumor Immunity	96
Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level	96
Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis	95
Reactive astrocytes facilitate vascular repair and remodeling after stroke	95
A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection	95
Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing	95
Enhanced evasion of neutralizing antibody response by Omicron XBB.1.5, CH.1.1, and CA.3.1 variants	94
Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2	94
Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans	93
Pro-inflammatory and proliferative microglia drive progression of glioblastoma	93
Systematic analysis of gut microbiome reveals the role of bacterial folate and homocysteine metabolism in Parkinson’s disease	92
Acute and persistent effects of commonly used antibiotics on the gut microbiome and resistome in healthy adults	92
Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing	91
Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics	90
Expression of miRNA-29 in Pancreatic β Cells Promotes Inflammation and Diabetes via TRAF3	90