OOIR: Observatory of International Research

Papers

(The TQCC of Bioresources and Bioprocessing is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Engineering of l-threonine and l-proline biosensors by directed evolution of transcriptional regulator SerR and application for high-throughput screening	156
De novo biosynthesis of quercetin in Yarrowia Lipolytica through systematic metabolic engineering for enhanced yield	131
Mining versatile feruloyl esterases: phylogenetic classification, structural features, and deep learning model	111
Harnessing the potency of scorpion venom-derived proteins: applications in cancer therapy	100
Biorefinery methods for extraction of oil and protein from rubber seed	95
Locally available agroresidues as potential sorbents: modelling, column studies and scale-up	73
Production of HMF-derivatives from wine residues using Saccharomyces cerevisiae as whole-cell biocatalyst	71
Coproduction of xylo-oligosaccharides and glucose from sugarcane bagasse in subcritical CO2-assisted seawater system	60
Engineering a high-sugar tolerant strain of Saccharomyces cerevisiae for efficient trehalose production using a cell surface display approach	59
Preparation of β(1→3)/β(1→4) xylooligosaccharides from red alga dulse by two xylanases from Streptomyces thermogriseus	59
l-Lactic acid production from fructose by chitosan film-coated sodium alginate-polyvinyl alcohol immobilized Lactobacillus pentosus cells and its kinetic analysis	56
Development and comparison of cell-free protein synthesis systems derived from typical bacterial chassis	55
Microbial lipid fermentation of Trichosporon cutaneum in high saline water	51
One-pot synthesis of (R)- and (S)-phenylglycinol from bio-based l-phenylalanine by an artificial biocatalytic cascade	49
Advances in engineering microbial biosynthesis of aromatic compounds and related compounds	46
Customized exogenous ferredoxin functions as an efficient electron carrier	45
Elucidating the degradation pattern of a new cold-tolerant pectate lyase used for efficient preparation of pectin oligosaccharides	45
A hemolysin secretion pathway-based novel secretory expression platform for efficient manufacturing of tag peptides and anti-microbial peptides in Escherichia coli	41
Engineering Escherichia coli biofilm to increase contact surface for shikimate and L-malate production	40
Enhanced l-ornithine production from glucose and sucrose via manipulation of the fructose metabolic pathway in Corynebacterium glutamicum	38
A novel thermophilic chitinase directly mined from the marine metagenome using the deep learning tool Preoptem	37
Selective biosynthesis of retinol in S. cerevisiae	37
A novel accessory protein ArCel5 from cellulose-gelatinizing fungus Arthrobotrys sp. CX1	37
De novo biosynthesis of τ-cadinol in engineered Escherichia coli	37
Sulphite addition during steam pretreatment enhanced both enzyme-mediated cellulose hydrolysis and ethanol production	36

Bioproduction of quercetin using recombinant thermostable glycosidases from Dictyoglomus thermophilum	33
Effective flow-through polishing strategies for knob-into-hole bispecific antibodies	31
Toxicity and inhibition mechanism of gallic acid on physiology and fermentation performance of Escherichia coli	30
Construction of an Escherichia coli cell factory to synthesize taxadien-5α-ol, the key precursor of anti-cancer drug paclitaxel	30
A novel sustainable platform for scaled manufacturing of double-stranded RNA biopesticides	30
Anti-vibriosis bioactive molecules from Arctic Penicillium sp. Z2230	29
Effects of turning frequency on fermentation efficiency and microbial community metabolic function of sheep manure composting on the Qinghai–Tibet Plateau	28
Enhancing menaquinone-7 biosynthesis by adaptive evolution of Bacillus natto through chemical modulator	28
Bioupgrading of the aqueous phase of pyrolysis oil from lignocellulosic biomass: a platform for renewable chemicals and fuels from the whole fraction of biomass	28
Differential transcriptome analysis of Sporocytophaga sp. CX11 and identification of candidate genes involved in lignocellulose degradation	28
Simultaneous photoautotrophic production of DHA and EPA by Tisochrysis lutea and Microchloropsis salina in co-culture	28
Construction and optimization of a biocatalytic route for the synthesis of neomenthylamine from menthone	27
Chitobiose exhibited a lipid-lowering effect in ob/ob−/− mice via butyric acid enrolled liver–gut crosstalk	27
Production of biliverdin by biotransformation of exogenous heme using recombinant Pichia pastoris cells	26
Enhancing the biosynthesis of taxadien-5α-yl-acetate in Escherichia coli by combinatorial metabolic engineering approaches	26
Potential of hospital wastewater treatment using locally isolated Chlorella sp. LH2 from cocoon wastewater	26
Intervention mechanism of marine-based chito-oligosaccharide on acute liver injury induced by AFB1 in rats	26
Network pharmacology and molecular docking: combined computational approaches to explore the antihypertensive potential of Fabaceae species	26
Discovery, characterization and mechanism of a Microbacterium esterase for key d-biotin chiral intermediate synthesis	25
An experimental study on the curing of desert sand using bio-cement	25
Identification of metabolites from the gut microbiota in hypertension via network pharmacology and molecular docking	24
Development of a microbial dewaxing agent using three spore forming bacteria	24
Fates of nutrient elements and heavy metals during thermal conversion of cattle slurry-derived anaerobic digestates	23
Minimization and optimization of α-amylase terminator for heterologous protein production in Bacillus licheniformis	22
Highly efficient synthesis of the chiral ACE inhibitor intermediate (R)-2-hydroxy-4-phenylbutyrate ethyl ester via engineered bi-enzyme coupled systems	22
Reshaping the binding channel of a novel GH113 family β-mannanase from Paenibacillus cineris (PcMan113) for enhanced activity	22
Optimized production of bacterioruberin from “Haloferax marinum” using one-factor-at-a-time and central composite design approaches	22
Physiological and transcriptome analysis elucidates the metabolic mechanism of versatile Porphyridium purpureum under nitrogen deprivation for exopolysaccharides accumulation	22
Enhancing synthetic vinasse treatment efficiency using an integrated UASB-Modified Bardenpho Process	22
Cultivation of earthworms and analysis of associated bacterial communities during earthworms’ growth using two types of agricultural wastes	21
Tea leaf exosome-like nanoparticles (TELNs) improve oleic acid-induced lipid metabolism by regulating miRNAs in HepG-2 cells	21
Effects of potassium on hydrothermal carbonization of sorghum bagasse	21
Optimization of tannase production by Aspergillus glaucus in solid-state fermentation of black tea waste	21
Correction: Produced water treatment by semi-continuous sequential bioreactor and microalgae photobioreactor	20
Biodegradation of olive mill solid waste by Anthracophyllum discolor and Stereum hirsutum: effect of copper and manganese supplementation	20
Downstream processing of recombinant human insulin and its analogues production from E. coli inclusion bodies	20
Development of highly efficient whole-cell catalysts of cis-epoxysuccinic acid hydrolase by surface display	19
Application of agro-waste-mediated silica nanoparticles to sustainable agriculture	19
Simultaneous degradation of two mycotoxins enabled by a fusion enzyme in food-grade recombinant Kluyveromyces lactis	19
Effects of bioelectricity generation processes on methane emission and bacterial community in wetland and carbon fate analysis	19
Different photosynthetic responses of haploid and diploid Emiliania huxleyi (Prymnesiophyceae) to high light and ultraviolet radiation	19
Micronization using combined alkaline protease hydrolysis and high-speed shearing homogenization for improving the functional properties of soy protein isolates	19
Optimization of operating parameters for biogas production using two-phase bench-scale anaerobic digestion of slaughterhouse wastewater: Focus on methanogenic step	19
Paper mulberry fruit juice: a novel biomass resource for bioethanol production	19
Flavor improving effects of cysteine in xylose–glycine–fish waste protein hydrolysates (FPHs) Maillard reaction system	18
Recent advances in catalytic synthesis of 2,5-furandimethanol from 5-hydroxymethylfurfural and carbohydrates	18
Optimization of extraction process and solvent polarities to enhance the recovery of phytochemical compounds, nutritional content, and biofunctional properties of Mentha longifolia L. extracts	18
Hydroxylases involved in terpenoid biosynthesis: a review	18
Prediction of phenolic compounds and glucose content from dilute inorganic acid pretreatment of lignocellulosic biomass using artificial neural network modeling	18
Salt-tolerant and thermostable mechanisms of an endoglucanase from marine Aspergillus niger	18

Adsorptive removal of levofloxacin and antibiotic resistance genes from hospital wastewater by nano-zero-valent iron and nano-copper using kinetic studies and response surface methodology	18
Enzymatic synthesis of high-titer nicotinamide mononucleotide with a new nicotinamide riboside kinase and an efficient ATP regeneration system	17
Harnessing cellulose-binding protein domains for the development of functionalized cellulose materials	17
Metabolic engineering of methylotrophic Pichia pastoris for the production of β-alanine	17
Synthetic biology promotes the capture of CO2 to produce fatty acid derivatives in microbial cell factories	17
Review on the extraction of bioactive compounds and characterization of fruit industry by-products	17
A modular 3D printed microfluidic system: a potential solution for continuous cell harvesting in large-scale bioprocessing	16
Efficient downstream processing of second-generation lactic acid from lignocellulosic waste using aqueous two-phase extraction	16
Enhancement of alkaline protease production in recombinant Bacillus licheniformis by response surface methodology	16
Membrane fractionation of hydrolysates of the water-soluble protein from tuna fish meal obtained by subcritical water and enzymatic treatments. Comparison of physical and chemical properties	16
The potential application of carbazole-degrading bacteria for dioxin bioremediation	16
Correction: Enhancement of lactate fraction in poly(lactate-co-3-hydroxybutyrate) biosynthesized by metabolically engineered E. coli	16
Separation of microalgae from bacterial contaminants using spiral microchannel in the presence of a chemoattractant	16
A novel scale-up strategy for cultivation of BHK-21 cells based on similar hydrodynamic environments in the bioreactors	16
Laccases as green and versatile biocatalysts: from lab to enzyme market—an overview	15
Production of bacterial cellulose from glycerol: the current state and perspectives	15
A comparative study of greener alternatives for nanocellulose production from sugarcane bagasse	15
Techno-economic analysis of a new downstream process for the production of astaxanthin from the microalgae Haematococcus pluvialis	15
Applications and analysis of hydrolysates in animal cell culture	15
Ionic liquid-based multi-stage sugaring-out extraction of lactic acid from simulated broth and actual lignocellulosic fermentation broth	15
Highly efficient production of transfructosylating enzymes using low-cost sugarcane molasses by A. pullulans FRR 5284	15
Combinatorial strategies for production improvement of anti-tuberculosis antibiotics ilamycins E1/E2 from deep sea-derived Streptomyces atratus SCSIO ZH16 ΔilaR	14
Valorization of porcine by-products: a combined process for protein hydrolysates and hydroxyapatite production	14
A green strategy to produce potential substitute resource for bear bile using engineered Saccharomyces cerevisiae	14
Induction of cellulase production by Sr2+ in Trichoderma reesei via calcium signaling transduction	13
High-efficiency secretory expression and characterization of the recombinant type III human-like collagen in Pichia pastoris	13
An accessory enzymatic system of cellulase for simultaneous saccharification and co-fermentation	13
Transcription regulation strategies in methylotrophs: progress and challenges	13
Two strategies to improve the supply of PKS extender units for ansamitocin P-3 biosynthesis by CRISPR–Cas9	13
Characterization of pH-responsive high molecular-weight chitosan/poly (vinyl alcohol) hydrogel prepared by gamma irradiation for localizing drug release	13
From pomiculture waste to biotechnological raw material: efficient transformation using ligninosomes and cellulosomes from Pleurotus spp.	13
Whole-cell one-pot biosynthesis of dodecanedioic acid from renewable linoleic acid	12
Spatial monitoring of hydrolysis in a plug-flow bioreactor: a support for flexible operation?	12
Tuning a bi-enzymatic cascade reaction in Escherichia coli to facilitate NADPH regeneration for ε-caprolactone production	12
Hyperthermophilic pretreatment composting can reduce ammonia emissions by controlling proteolytic bacterial community and the physicochemical properties	12
Reduction of phenolics in faba bean meal using recombinantly produced and purified Bacillus ligniniphilus catechol 2,3-dioxygenase	12
Precise regulating the specific oxygen consumption rate to strengthen the CoQ10 biosynthesis by Rhodobater sphaeroides	12
Investigation on environmental factors contributing to bispecific antibody stability and the reversal of self-associated aggregates	12
Study on active capacity and detergent application potential of low-temperature alkaline serine protease produced by new strain Exiguobacterium indicum 1.2.3	12
RETRACTED ARTICLE: Microwave-ultrasonic assisted extraction of lignin to synthesize new nano micellar organometallic surfactants for refining oily wastewater	12
Construction of the genetic switches in response to mannitol based on artificial MtlR box	12
Point mutation of V252 in neomycin C epimerase enlarges substrate-binding pocket and improves neomycin B accumulation in Streptomyces fradiae	12
Extractive adsorption of 1,3-propanediol on a novel polystyrene macroporous resin enclosing medium and long-chain alcohols as extractant	12
Produced water treatment by semi-continuous sequential bioreactor and microalgae photobioreactor	12
Effects of lactic acid bacteria and cellulase additives on the fermentation quality, antioxidant activity, and metabolic profile of oat silage	12
Influence of light absorption rate on the astaxanthin production by the microalga Haematococcus pluvialis during nitrogen starvation	12
Retraction Note: Mutagenesis combined with fermentation optimization to enhance gibberellic acid GA3 yield in Fusarium fujikuroi	12
Preparation of cellulose nanocrystals from commercial dissolving pulp using an engineered cellulase system	12
Biocompatible natural deep eutectic solvent-based extraction and cellulolytic enzyme-mediated transformation of Pueraria mirifica isoflavones: a sustainable approach for increasing health-bioactive co	12
In vitro study on antioxidant and lipid-lowering activities of tobacco polysaccharides	12