OOIR: Observatory of International Research

Papers

(The H4-Index of Drug Delivery and Translational Research is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Efficacy of a Zn-based metalorganic framework doped with benznidazole on acute experimental Trypanosoma cruzi infection	160
Correction to: Alginate-liposomal construct for bupivacaine delivery and MSC function regulation	140
Anti-tumor antibody isotype response can be modified with locally administered immunoadjuvants	134
Correction to: Self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel and carvacrol synergizes the anticancer activity and enables safer toxicity profile: optimization, and in-vitro, ex-vivo	132
Medium-chain triglyceride-stabilized docetaxel-loaded HSA nanoparticles effectively inhibited metastatic non-small cell lung cancer	75
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study	69
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia–reperfusion injury through the KEAP1/Nrf2/HO-1 signaling	66
Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 23 full factorial design	64
Nanoemulsion-based dissolving microneedle arrays for enhanced intradermal and transdermal delivery	60
Development of doxorubicin hydrochloride–loaded whey protein nanoparticles and its surface modification with N-acetyl cysteine for triple-negative breast cancer	56
Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway	55
Nano-delivery of a novel inhibitor of ERCC1-XPF for targeted sensitization of colorectal cancer to platinum-based chemotherapeutics	55
Development and optimization of a self micro-emulsifying drug delivery system (SMEDDS) for co-administration of sorafenib and curcumin	54
Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product	51
Wheat germ agglutinin modified mixed micelles overcome the dual barrier of mucus/enterocytes for effective oral absorption of shikonin and gefitinib	51
Nanomedicines and nanocarriers in clinical trials: surfing through regulatory requirements and physico-chemical critical quality attributes	48
Multitarget, multiagent PLGA nanoparticles for simultaneous tumor eradication and TME remodeling in a melanoma mouse model	47
pH-sensitive liposomes bearing a chemotherapeutic agent and a natural apoptosis modulator for effective intracellular delivery to the solid tumor	46
Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization	46
Harnessing curcumin in a multifunctional biodegradable metal-organic framework (bio-MOF) for targeted colorectal cancer theranostics	45
Protacs in cancer therapy: mechanisms, design, clinical trials, and future directions	44
Biodegradable polymeric microsphere formulations of full-length anti-VEGF antibody bevacizumab for sustained intraocular delivery	44
Tunable polymeric micelles for taxane and corticosteroid co-delivery	44
Correction: Shape-specific microfabricated particles for biomedical applications: a review	44
Delivery of exogenous miR-19b by Wharton’s Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism	43

Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence	43
Customized 3D-printed hollow capsular device filled with norfloxacin-loaded micropellets for controlled-release delivery	42
Critical evaluation of saponin as a permeabilizer for anandamide encapsulation in extracellular vesicles	42
Therapeutic approaches for targeting the pediatric brain tumor microenvironment	42
Oleogels for the ocular delivery of epalrestat: formulation, in vitro, in ovo, ex vivo and in vivo evaluation	42
Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm	42
Exploring paclitaxel-loaded adenosine-conjugated PEGylated PLGA nanoparticles for targeting triple-negative breast cancer	41
Exploration of Abiraterone acetate loaded Nanostructured lipid carriers for bioavailability improvement and circumvention of fast-fed variability	40
A virtual factory for topical formulations based on molecular modeling and drug-polymer interaction studies	40
Subcellular detection of PEBCA particles in macrophages: combining darkfield microscopy, confocal Raman microscopy, and ToF–SIMS analysis	39
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension	38
Phenytoin-loaded bioactive nanoparticles for the treatment of diabetic pressure ulcers: formulation and in vitro/in vivo evaluation	37