OOIR: Observatory of International Research

Papers

(The H4-Index of Drug Delivery and Translational Research is 42. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Anti-tumor antibody isotype response can be modified with locally administered immunoadjuvants	221
Precision engineering of anti-atherosclerotic herbal nanomedicine: from machine learning-aided active components screening to optimized metal-phenolic network codelivery	173
pH-sensitive liposomes bearing a chemotherapeutic agent and a natural apoptosis modulator for effective intracellular delivery to the solid tumor	166
Correction to: Self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel and carvacrol synergizes the anticancer activity and enables safer toxicity profile: optimization, and in-vitro, ex-vivo	121
Wheat germ agglutinin modified mixed micelles overcome the dual barrier of mucus/enterocytes for effective oral absorption of shikonin and gefitinib	92
Medium-chain triglyceride-stabilized docetaxel-loaded HSA nanoparticles effectively inhibited metastatic non-small cell lung cancer	88
Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization	84
Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 23 full factorial design	78
Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway	71
Preparation of Tanshinone IIA and glycyrrhetinic acid emulsion and preliminary study on its anti-psoriasis efficacy	68
Multitarget, multiagent PLGA nanoparticles for simultaneous tumor eradication and TME remodeling in a melanoma mouse model	68
Tunable polymeric micelles for taxane and corticosteroid co-delivery	67
Formulation considerations in enhancing olfactory mucosal deposition for nose-to-brain drug delivery	67
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia–reperfusion injury through the KEAP1/Nrf2/HO-1 signaling	66
Efficacy of a Zn-based metalorganic framework doped with benznidazole on acute experimental Trypanosoma cruzi infection	65
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study	60
Nano-delivery of a novel inhibitor of ERCC1-XPF for targeted sensitization of colorectal cancer to platinum-based chemotherapeutics	58
Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product	57
Harnessing curcumin in a multifunctional biodegradable metal-organic framework (bio-MOF) for targeted colorectal cancer theranostics	56
Protacs in cancer therapy: mechanisms, design, clinical trials, and future directions	54
Development and optimization of a self micro-emulsifying drug delivery system (SMEDDS) for co-administration of sorafenib and curcumin	54
Customized 3D-printed hollow capsular device filled with norfloxacin-loaded micropellets for controlled-release delivery	53
Nanomedicines and nanocarriers in clinical trials: surfing through regulatory requirements and physico-chemical critical quality attributes	53
Beyond the dose: a clearance-enabled in vitro platform for evaluating local therapies	51
Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence	51

A review of formulations and preclinical studies of inhaled rifampicin for its clinical translation	51
Biodegradable polymeric microsphere formulations of full-length anti-VEGF antibody bevacizumab for sustained intraocular delivery	50
Fucoidan, a brown seaweed polysaccharide in nanodrug delivery	50
Natural herb wormwood-based microneedle array for wound healing	48
Critical evaluation of saponin as a permeabilizer for anandamide encapsulation in extracellular vesicles	48
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension	47
Biodegradable microneedles for transdermal sitagliptin delivery: in vivo insights into enhanced diabetes management	47
Bortezomib-loaded hybrid liposome inducing pyroptosis for targeted therapy against colorectal cancer	46
Quality by design (QbD) approach to develop fast-dissolving tablets using melt-dispersion paired with surface-adsorption method: formulation and pharmacokinetics of flurbiprofen melt-dispersion granul	46
A virtual factory for topical formulations based on molecular modeling and drug-polymer interaction studies	46
Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm	45
Exploration of Abiraterone acetate loaded Nanostructured lipid carriers for bioavailability improvement and circumvention of fast-fed variability	45
Correction: Shape-specific microfabricated particles for biomedical applications: a review	45
Oleogels for the ocular delivery of epalrestat: formulation, in vitro, in ovo, ex vivo and in vivo evaluation	43
Delivery of exogenous miR-19b by Wharton’s Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism	43
Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices	43
Therapeutic approaches for targeting the pediatric brain tumor microenvironment	43