OOIR: Observatory of International Research

Papers

(The H4-Index of Drug Delivery and Translational Research is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Anti-tumor antibody isotype response can be modified with locally administered immunoadjuvants	177
Correction to: Self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel and carvacrol synergizes the anticancer activity and enables safer toxicity profile: optimization, and in-vitro, ex-vivo	149
Medium-chain triglyceride-stabilized docetaxel-loaded HSA nanoparticles effectively inhibited metastatic non-small cell lung cancer	145
Nano-delivery of a novel inhibitor of ERCC1-XPF for targeted sensitization of colorectal cancer to platinum-based chemotherapeutics	144
Bioavailability enhancement and neuropharmacological effects of Dauricine under intranasal administration to improve cognitive impairment via PI3K/AKT/mTOR pathway	80
Precision engineering of anti-atherosclerotic herbal nanomedicine: from machine learning-aided active components screening to optimized metal-phenolic network codelivery	73
pH-sensitive liposomes bearing a chemotherapeutic agent and a natural apoptosis modulator for effective intracellular delivery to the solid tumor	70
Multitarget, multiagent PLGA nanoparticles for simultaneous tumor eradication and TME remodeling in a melanoma mouse model	69
Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization	66
Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product	60
Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 23 full factorial design	60
Tunable polymeric micelles for taxane and corticosteroid co-delivery	58
Efficacy of a Zn-based metalorganic framework doped with benznidazole on acute experimental Trypanosoma cruzi infection	58
Wheat germ agglutinin modified mixed micelles overcome the dual barrier of mucus/enterocytes for effective oral absorption of shikonin and gefitinib	56
Development and optimization of a self micro-emulsifying drug delivery system (SMEDDS) for co-administration of sorafenib and curcumin	53
Protacs in cancer therapy: mechanisms, design, clinical trials, and future directions	50
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study	50
Harnessing curcumin in a multifunctional biodegradable metal-organic framework (bio-MOF) for targeted colorectal cancer theranostics	49
Development of doxorubicin hydrochloride–loaded whey protein nanoparticles and its surface modification with N-acetyl cysteine for triple-negative breast cancer	48
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia–reperfusion injury through the KEAP1/Nrf2/HO-1 signaling	48
Preparation of Tanshinone IIA and glycyrrhetinic acid emulsion and preliminary study on its anti-psoriasis efficacy	48
Correction: Shape-specific microfabricated particles for biomedical applications: a review	48
Nanomedicines and nanocarriers in clinical trials: surfing through regulatory requirements and physico-chemical critical quality attributes	48
Delivery of exogenous miR-19b by Wharton’s Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism	46
Customized 3D-printed hollow capsular device filled with norfloxacin-loaded micropellets for controlled-release delivery	44

Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices	43
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension	43
Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence	43
Critical evaluation of saponin as a permeabilizer for anandamide encapsulation in extracellular vesicles	43
Natural herb wormwood-based microneedle array for wound healing	43
Phenytoin-loaded bioactive nanoparticles for the treatment of diabetic pressure ulcers: formulation and in vitro/in vivo evaluation	43
Adventitial injection of HA/SA hydrogel loaded with PLGA rapamycin nanoparticle inhibits neointimal hyperplasia in a rat aortic wire injury model	42
Bortezomib-loaded hybrid liposome inducing pyroptosis for targeted therapy against colorectal cancer	42
Exploration of Abiraterone acetate loaded Nanostructured lipid carriers for bioavailability improvement and circumvention of fast-fed variability	41
Biodegradable microneedles for transdermal sitagliptin delivery: in vivo insights into enhanced diabetes management	41
A virtual factory for topical formulations based on molecular modeling and drug-polymer interaction studies	41
Therapeutic approaches for targeting the pediatric brain tumor microenvironment	41
Biodegradable polymeric microsphere formulations of full-length anti-VEGF antibody bevacizumab for sustained intraocular delivery	40
Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm	40
Subcellular detection of PEBCA particles in macrophages: combining darkfield microscopy, confocal Raman microscopy, and ToF–SIMS analysis	39