OOIR: Observatory of International Research

Papers

(The H4-Index of Drug Delivery and Translational Research is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Anti-tumor antibody isotype response can be modified with locally administered immunoadjuvants	189
Development of doxorubicin hydrochloride–loaded whey protein nanoparticles and its surface modification with N-acetyl cysteine for triple-negative breast cancer	110
Correction to: Self-nanoemulsifying drug delivery system (SNEDDS) of docetaxel and carvacrol synergizes the anticancer activity and enables safer toxicity profile: optimization, and in-vitro, ex-vivo	102
Formulation of tizanidine hydrochloride–loaded provesicular system for improved oral delivery and therapeutic activity employing a 23 full factorial design	102
Microfluidics-on-a-chip for designing celecoxib-based amorphous solid dispersions: when the process shapes the product	98
Correction to: Alginate-liposomal construct for bupivacaine delivery and MSC function regulation	73
Efficacy of a Zn-based metalorganic framework doped with benznidazole on acute experimental Trypanosoma cruzi infection	54
Wheat germ agglutinin modified mixed micelles overcome the dual barrier of mucus/enterocytes for effective oral absorption of shikonin and gefitinib	53
Nano-delivery of a novel inhibitor of ERCC1-XPF for targeted sensitization of colorectal cancer to platinum-based chemotherapeutics	53
Development and optimization of a self micro-emulsifying drug delivery system (SMEDDS) for co-administration of sorafenib and curcumin	53
Multitarget, multiagent PLGA nanoparticles for simultaneous tumor eradication and TME remodeling in a melanoma mouse model	52
Harnessing curcumin in a multifunctional biodegradable metal-organic framework (bio-MOF) for targeted colorectal cancer theranostics	45
hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia–reperfusion injury through the KEAP1/Nrf2/HO-1 signaling	44
Overcoming physical stromal barriers to cancer immunotherapy	44
Medium-chain triglyceride-stabilized docetaxel-loaded HSA nanoparticles effectively inhibited metastatic non-small cell lung cancer	43
Protacs in cancer therapy: mechanisms, design, clinical trials, and future directions	43
Nanoemulsion-based dissolving microneedle arrays for enhanced intradermal and transdermal delivery	43
A large-volume low-pressure nasal irrigation delivers drug into the nasal cavity? An in vivo study	42
Nanomedicines and nanocarriers in clinical trials: surfing through regulatory requirements and physico-chemical critical quality attributes	42
Tunable polymeric micelles for taxane and corticosteroid co-delivery	42
pH-sensitive liposomes bearing a chemotherapeutic agent and a natural apoptosis modulator for effective intracellular delivery to the solid tumor	42
Quality by design (QbD) approach to develop fast-dissolving tablets using melt-dispersion paired with surface-adsorption method: formulation and pharmacokinetics of flurbiprofen melt-dispersion granul	41
Pressure pulsations enhance penetration index in COPD	41
Simvastatin-loaded nano-niosomes confer cardioprotection against myocardial ischemia/reperfusion injury	40
Delivery of exogenous miR-19b by Wharton’s Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism	39

Bortezomib-loaded hybrid liposome inducing pyroptosis for targeted therapy against colorectal cancer	39
Oleogels for the ocular delivery of epalrestat: formulation, in vitro, in ovo, ex vivo and in vivo evaluation	39
Customized 3D-printed hollow capsular device filled with norfloxacin-loaded micropellets for controlled-release delivery	38
Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective	38
Therapeutic approaches for targeting the pediatric brain tumor microenvironment	36
Chronotherapy based on modified-release hydrocortisone to restore the physiological cortisol diurnal rhythm	36
Fucoidan, a brown seaweed polysaccharide in nanodrug delivery	35
Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices	35
Enhancing anti-tumor therapy with agmatine-cholesterol conjugate liposomes: in vitro and in vivo evidence	35
A ready-to-use, thermoresponsive, and extended-release delivery system for the paranasal sinuses	34
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension	34
Self-assembled polyelectrolyte complexes of chitosan and fucoidan for sustained growth factor release from PRP enhance proliferation and collagen deposition in diabetic mice	34