Bioengineered

Article	Citations
A critical review on advances in the practices and perspectives for the treatment of dye industry wastewater	441
Health hazards of hexavalent chromium (Cr (VI)) and its microbial reduction	256
Antibiotics: An overview on the environmental occurrence, toxicity, degradation, and removal methods	195
Microbiological insights into anaerobic digestion for biogas, hydrogen or volatile fatty acids (VFAs): a review	172
Naringenin alleviates myocardial ischemia/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) /System xc-/ glutathione peroxidase 4 (GPX4) axis to inhibit fe	140
Ferrostatin-1 alleviates lipopolysaccharide-induced cardiac dysfunction	112
Microbial biosurfactants: a review of recent environmental applications	109
A novel pyroptosis-related lncRNA signature for prognostic prediction in patients with lung adenocarcinoma	82
Interleukin-6 promotes ferroptosis in bronchial epithelial cells by inducing reactive oxygen species-dependent lipid peroxidation and disrupting iron homeostasis	79
A comprehensive review on the use of algal-bacterial systems for wastewater treatment with emphasis on nutrient and micropollutant removal	69
The roles of microbial products in the development of colorectal cancer: a review	68
Physiology of microalgal biofilm: a review on prediction of adhesion on substrates	67
An overview of microalgae biomass as a sustainable aquaculture feed ingredient: food security and circular economy	67
Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling	65
A review of the therapeutic and biological effects of edible and wild mushrooms	65
A Glimpse of the World of Volatile Fatty Acids Production and Application: A review	65
Apple orchard waste recycling and valorization of valuable product-A review	62
Lapatinib induces mitochondrial dysfunction to enhance oxidative stress and ferroptosis in doxorubicin-induced cardiomyocytes via inhibition of PI3K/AKT signaling pathway	61
Astragaloside-IV alleviates high glucose-induced ferroptosis in retinal pigment epithelial cells by disrupting the expression of miR-138-5p/Sirt1/Nrf2	61
New challenges in the use of nanomedicine in cancer therapy	60
Production of polyhydroxyalkanoates (PHAs) by Bacillus megaterium using food waste acidogenic fermentation-derived volatile fatty acids	59
Biofuel production from Macroalgae: present scenario and future scope	58
Transferrin receptor-mediated reactive oxygen species promotes ferroptosis of KGN cells via regulating NADPH oxidase 1/PTEN induced kinase 1/acyl-CoA synthetase long chain family member 4 signaling	58
Lipocalin-2 silencing suppresses inflammation and oxidative stress of acute respiratory distress syndrome by ferroptosis via inhibition of MAPK/ERK pathway in neonatal mice	58
Mechanism of cargo sorting into small extracellular vesicles	58

Identification of important genes related to ferroptosis and hypoxia in acute myocardial infarction based on WGCNA	55
Crosstalk of pyroptosis, ferroptosis, and mitochondrial aldehyde dehydrogenase 2-related mechanisms in sepsis-induced lung injury in a mouse model	52
Bacterial nanocellulose: engineering, production, and applications	51
A review on biofiltration techniques: recent advancements in the removal of volatile organic compounds and heavy metals in the treatment of polluted water	51
Recovery of resources from industrial wastewater employing electrochemical technologies: status, advancements and perspectives	51
Sustainable mitigation of heavy metals from effluents: Toxicity and fate with recent technological advancements	51
Ropivacaine inhibits the proliferation and migration of colorectal cancer cells through ITGB1	49
Platycodin D regulates high glucose-induced ferroptosis of HK-2 cells through glutathione peroxidase 4 (GPX4)	49
Cancer-associated fibroblast exosomes promote chemoresistance to cisplatin in hepatocellular carcinoma through circZFR targeting signal transducers and activators of transcription (STAT3)/ nuclear fac	49
Genetic modification for enhancing bacterial cellulose production and its applications	49
Composting and its application in bioremediation of organic contaminants	48
Activating transcription factor 3 (ATF3) regulates cell growth, apoptosis, invasion and collagen synthesis in keloid fibroblast through transforming growth factor beta (TGF-beta)/SMAD signaling pathwa	47
Multifunctional applications of bamboo crop beyond environmental management: an Indian prospective	47
A pan-cancer analysis of the prognostic and immunological role of β-actin (ACTB) in human cancers	47
Circular RNA circ_0001287 inhibits the proliferation, metastasis, and radiosensitivity of non-small cell lung cancer cells by sponging microRNA miR-21 and up-regulating phosphatase and tensin homolog	46
Liraglutide attenuates hepatic iron levels and ferroptosis in db/db mice	46
Circular RNA FAT atypical cadherin 1 (circFAT1)/microRNA-525-5p/spindle and kinetochore-associated complex subunit 1 (SKA1) axis regulates oxaliplatin resistance in breast cancer by activating the not	44
COVID-19 in Southeast Asia: current status and perspectives	44
Algae-derived hydrocolloids in foods: applications and health-related issues	44
Based on network pharmacology and in vitro experiments to prove the effective inhibition of myocardial fibrosis by Buyang Huanwu decoction	44
Diatom microalgae as smart nanocontainers for biosensing wastewater pollutants: recent trends and innovations	43
Analysis of mRNA‑lncRNA and mRNA‑lncRNA-pathway co‑expression networks based on WGCNA in developing pediatric sepsis	43
Plant microbe based remediation approaches in dye removal: A review	43
Quercetin alleviates chronic renal failure by targeting the PI3k/Akt pathway	42
Tumor-derived exosomal miRNA-141 promote angiogenesis and malignant progression of lung cancer by targeting growth arrest-specific homeobox gene (GAX)	42
A review of biosensor for environmental monitoring: principle, application, and corresponding achievement of sustainable development goals	42
Long non-coding RNA (LncRNA) MRPL23-AS1 promotes tumor progression and carcinogenesis in osteosarcoma by activating Wnt/β-catenin signaling via inhibiting microRNA miR-30b and upregulating myosin heav	41
lncRNA DANCR promotes the migration an invasion and of trophoblast cells through microRNA-214-5p in preeclampsia	41
Bioengineered microbes for soil health restoration: present status and future	41
Microbial electrolysis: a promising approach for treatment and resource recovery from industrial wastewater	41
Downregulation of fatty acid binding protein 4 alleviates lipid peroxidation and oxidative stress in diabetic retinopathy by regulating peroxisome proliferator-activated receptor γ-mediated ferroptosi	41
Bioengineered biochar as smart candidate for resource recovery toward circular bio-economy: a review	40
Catalpol ameliorates psoriasis-like phenotypes via SIRT1 mediated suppression of NF-κB and MAPKs signaling pathways	40
Effects of wound dressing based on the combination of silver@curcumin nanoparticles and electrospun chitosan nanofibers on wound healing	39
N6-methyladenosine (m6A)-mediated up-regulation of long noncoding RNA LINC01320 promotes the proliferation, migration, and invasion of gastric cancer via miR495-5p/RAB19 axis	39
Bupivacaine modulates the apoptosis and ferroptosis in bladder cancer via phosphatidylinositol 3-kinase (PI3K)/AKT pathway	39
Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics	39
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells	39
Long non-coding RNA H19 protects against intracerebral hemorrhage injuries via regulating microRNA-106b-5p/acyl-CoA synthetase long chain family member 4 axis	39
Downregulation of Circular RNA PSEN1 ameliorates ferroptosis of the high glucose treated retinal pigment epithelial cells via miR-200b-3p/cofilin-2 axis	39
miR-125a-5p-abundant exosomes derived from mesenchymal stem cells suppress chondrocyte degeneration via targeting E2F2 in traumatic osteoarthritis	39
The gut microbial diversity of colon cancer patients and the clinical significance	38
m6A demethylase FTO regulates the apoptosis and inflammation of cardiomyocytes via YAP1 in ischemia-reperfusion injury	37
Upregulated circRNA_102231 promotes gastric cancer progression and its clinical significance	37
Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway	37
Quercetin modulates the gut microbiota as well as the metabolome in a rat model of osteoarthritis	37
Inhibin β-A (INHBA) induces epithelial–mesenchymal transition and accelerates the motility of breast cancer cells by activating the TGF-β signaling pathway	36
The role of human mast cells in allergy and asthma	36
RETRACTED ARTICLE: Circular RNA protein tyrosine kinase 2 (circPTK2) promotes colorectal cancer proliferation, migration, invasion and chemoresistance	36
MicroRNA miR-330-3p suppresses the progression of ovarian cancer by targeting RIPK4	35

Overexpression of PLK1 relieved the myocardial ischemia-reperfusion injury of rats through inducing the mitophagy and regulating the p-AMPK/FUNDC1 axis	34
Circular RNA circ_0001162 promotes cell proliferation and invasion of glioma via the miR-936/ERBB4 axis	34
Characteristics of immune cell infiltration and associated diagnostic biomarkers in ulcerative colitis: results from bioinformatics analysis	34
Improvement of intestinal barrier function, gut microbiota, and metabolic endotoxemia in type 2 diabetes rats by curcumin	34
Identification and validation of a novel redox-related lncRNA prognostic signature in lung adenocarcinoma	34
Formononetin protects against ox-LDL-induced endothelial dysfunction by activating PPAR-γ signaling based on network pharmacology and experimental validation	34
Trichosanthin inhibits cervical cancer by regulating oxidative stress-induced apoptosis	34
Application of cell culture technology and genetic engineering for production of future foods and crop improvement to strengthen food security	34
Comprehensive review on biotechnological production of hyaluronic acid: status, innovation, market and applications	33
LncRNA ROR/miR-145-5p axis modulates the osteoblasts proliferation and apoptosis in osteoporosis	33
A critical review on microbial carbonate precipitation via denitrification process in building materials	33
Baicalin suppresses autophagy-dependent ferroptosis in early brain injury after subarachnoid hemorrhage	33
LINC00839/miR-144-3p/WTAP (WT1 Associated protein) axis is involved in regulating hepatocellular carcinoma progression	33
Production of L-carnitine-enriched edible filamentous fungal biomass through submerged cultivation	33
The mechanism of intestinal flora dysregulation mediated by intestinal bacterial biofilm to induce constipation	33
Advances in biomaterial production from animal derived waste	32
Development and validation of a novel N6-methyladenosine (m6A)-related multi- long non-coding RNA (lncRNA) prognostic signature in pancreatic adenocarcinoma	32
Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic knee	32
Oral squamous cell carcinoma (OSCC)-derived exosomal MiR-221 targets and regulates phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1) to promote human umbilical vein endothelial cells migration a	32
Active pharmaceutical ingredient (API) chemicals: a critical review of current biotechnological approaches	32
N6-methyladenosine (m6A)-mediated lncRNA DLGAP1-AS1enhances breast canceradriamycin resistance through miR-299-3p/WTAP feedback loop	32
Paeoniflorin ameliorates chronic stress-induced depression-like behavior in mice model by affecting ERK1/2 pathway	32
Circular RNA circ_0003028 contributes to tumorigenesis by regulating GOT2 via miR-1298-5p in non-small cell lung cancer	32
MicroRNA miR-126 attenuates brain injury in septic rats via NF-κB signaling pathway	31
MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway	31
Circular RNA circ_0000020 promotes osteogenic differentiation to reduce osteoporosis via sponging microRNA miR-142-5p to up-regulate Bone Morphogenetic Protein BMP2	31
Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification	31
Rosmarinic acid inhibits proliferation and migration, promotes apoptosis and enhances cisplatin sensitivity of melanoma cells through inhibiting ADAM17/EGFR/AKT/GSK3β axis	31
Can algae contribute to the war with Covid-19?	31
Microbial engineering for the production of isobutanol: current status and future directions	31
Muscleblind-like 1 antisense RNA 1 inhibits cell proliferation, invasion, and migration of prostate cancer by sponging miR-181a-5p and regulating PTEN/PI3K/AKT/mTOR signaling	31
Pyrroloquinoline quinone (PQQ) alleviated sepsis-induced acute liver injury, inflammation, oxidative stress and cell apoptosis by downregulating CUL3 expression	31
Insulin-like growth factor 2 mRNA-binding protein 2-stabilized long non-coding RNA Taurine up-regulated gene 1 (TUG1) promotes cisplatin-resistance of colorectal cancer via modulating autophagy	31
Changes in the gut microbiome and metabolome in a rat model of pulmonary arterial hypertension	31
Stigmasterol alleviates interleukin-1beta-induced chondrocyte injury by down-regulatingsterol regulatory element binding transcription factor 2 to regulateferroptosis	30
The role of gut microbiota in patients with benign and malignant brain tumors: a pilot study	30
Identification and verification of vascular cell adhesion protein 1 as an immune-related hub gene associated with the tubulointerstitial injury in diabetic kidney disease	30
The global status of research in breast cancer liver metastasis: a bibliometric and visualized analysis	30
Resveratrol-modified mesoporous silica nanoparticle for tumor-targeted therapy of gastric cancer	30
Exosomes from human adipose-derived mesenchymal stem cells inhibit production of extracellular matrix in keloid fibroblasts via downregulating transforming growth factor-β2 and Notch-1 expression	30
Exploring the role of microbial biofilm for industrial effluents treatment	30
Long non-coding RNA MCM3AP-AS1 protects chondrocytes ATDC5 and CHON-001 from IL-1β-induced inflammation via regulating miR-138-5p/SIRT1	30
Phloretin inhibited the pathogenicity and virulence factors against Candida albicans	30
Recent advances in metabolic engineering of microorganisms for advancing lignocellulose-derived biofuels	29
RETRACTED ARTICLE: Exosome-delivered BMP-2 and polyaspartic acid promotes tendon bone healing in rotator cuff tear via Smad/RUNX2 signaling pathway	29
Differentially-expressed mRNAs, microRNAs and long noncoding RNAs in intervertebral disc degeneration identified by RNA-sequencing	29
Bacterial Cellulose Production from agricultural Residues by two Komagataeibacter sp. Strains	29
Long non-coding RNA LINC00649 regulates YES-associated protein 1 (YAP1)/Hippo pathway to accelerate gastric cancer (GC) progression via sequestering miR-16-5p	29
Silencing of long non-coding RNA HCP5 inhibits proliferation, invasion, migration, and promotes apoptosis via regulation of miR-299-3p/SMAD5 axis in gastric cancer cells	29
Circular RNA hsa_circ_0005567 overexpression promotes M2 type macrophage polarization through miR-492/SOCS2 axis to inhibit osteoarthritis progression	29
Long non-coding RNA nuclear enriched abundant transcript 1 (NEAT1) sponges microRNA-124-3p to up-regulate phosphodiesterase 4B (PDE4B) to accelerate the progression of Parkinson’s disease	29
Circular RNA circ_0000467 regulates colorectal cancer development via miR-382-5p/EN2 axis	29
Dynamic changes of intestinal flora in patients with irritable bowel syndrome combined with anxiety and depression after oral administration of enterobacteria capsules	29
A novel circRNA-miRNA-mRNA network revealed exosomal circ-ATP10A as a biomarker for multiple myeloma angiogenesis	29
Recent advances in microbial engineering approaches for wastewater treatment: a review	28
Glyphosate escalates horizontal transfer of conjugative plasmid harboring antibiotic resistance genes	28
Integrated analysis of hypoxia-associated lncRNA signature to predict prognosis and immune microenvironment of lung adenocarcinoma patients	28
A circular RNA, circUSP36, accelerates endothelial cell dysfunction in atherosclerosis by adsorbing miR-637 to enhance WNT4 expression	28
Sophorolipid: a glycolipid biosurfactant as a potential therapeutic agent against COVID-19	28
SNAI2 promotes the development of ovarian cancer through regulating ferroptosis	28
LncRNA SNHG12 in extracellular vesicles derived from carcinoma-associated fibroblasts promotes cisplatin resistance in non-small cell lung cancer cells	28
LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway	28
GIT1 overexpression promotes epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma	28
DNA methylation across the tree of life, from micro to macro-organism	28
Disulfiram/Copper induces antitumor activity against gastric cancer via the ROS/MAPK and NPL4 pathways	28
Prodigiosin: a promising biomolecule with many potential biomedical applications	28
MiR-19a suppresses ferroptosis of colorectal cancer cells by targeting IREB2	28
A novel ferroptosis-related gene signature for predicting outcomes in cervical cancer	27
Long non-coding RNA NORAD protects against cerebral ischemia/reperfusion injury induced brain damage, cell apoptosis, oxidative stress and inflammation by regulating miR-30a-5p/YWHAG	27
Recent advancements in prebiotic oligomers synthesis via enzymatic hydrolysis of lignocellulosic biomass	27
Type IIA topoisomerase (TOP2A) triggers epithelial-mesenchymal transition and facilitates HCC progression by regulating Snail expression	27
Suppression of lncRNA Gm47283 attenuates myocardial infarction via miR-706/ Ptgs2/ferroptosis axis	27
SP1-induced lncRNA ZFPM2 antisense RNA 1 (ZFPM2-AS1) aggravates glioma progression via the miR-515-5p/Superoxide dismutase 2 (SOD2) axis	27
Prognostic and therapeutic significance of a novel ferroptosis related signature in colorectal cancer patients	27
Fat mass and obesity-associated protein (FTO) mediates signal transducer and activator of transcription 3 (STAT3)-drived resistance of breast cancer to doxorubicin	26
The ubiquitin hydrolase OTUB1 promotes glioma cell stemness via suppressing ferroptosis through stabilizing SLC7A11 protein	26
Resveratrol acts via the mitogen-activated protein kinase (MAPK) pathway to protect retinal ganglion cells from apoptosis induced by hydrogen peroxide	26
Circular RNA ZNF609 functions as a competing endogenous RNA in regulating E2F transcription factor 6 through competitively binding to microRNA-197-3p to promote the progression of cervical cancer prog	26
Soy isoflavones alleviate polycystic ovary syndrome in rats by regulating NF- κB signaling pathway	26
Gut Microbiota Characterization in Patients with Asymptomatic Hyperuricemia: probiotics increased	26

MicroRNA miR-92a-3p regulates breast cancer cell proliferation and metastasis via regulating B-cell translocation gene 2 (BTG2)	26
Knockdown of long non-coding RNA NEAT1 relieves the inflammatory response of spinal cord injury through targeting miR-211-5p/MAPK1 axis	26
Identification of candidate biomarkers correlated with poor prognosis of breast cancer based on bioinformatics analysis	26
Sulforaphane protects intestinal epithelial cells against lipopolysaccharide-induced injury by activating the AMPK/SIRT1/PGC-1ɑ pathway	26
The regulation of long non-coding RNA 00958 (LINC00958) for oral squamous cell carcinoma (OSCC) cells death through absent in melanoma 2 (AIM2) depending on microRNA-4306 and Sirtuin1 (SIRT1) in vitro	26
Circ_nuclear factor I X (circNfix) attenuates pressure overload-induced cardiac hypertrophy via regulating miR-145-5p/ATF3 axis	26
Bone mesenchymal stem cell-derived extracellular vesicles deliver microRNA-23b to alleviate spinal cord injury by targeting toll-like receptor TLR4 and inhibiting NF-κB pathway activation	25
m6A RNA methylation regulators were associated with the malignancy and prognosis of ovarian cancer	25
Challenges of pathogen inactivation in animal manure through anaerobic digestion: a short review	25
Identification of fibronectin 1 (FN1) and complement component 3 (C3) as immune infiltration-related biomarkers for diabetic nephropathy using integrated bioinformatic analysis	25
miRNA-93-5p in exosomes derived from M2 macrophages improves lipopolysaccharide-induced podocyte apoptosis by targeting Toll-like receptor 4	25
Long non-coding RNA LINC00997 silencing inhibits the progression and metastasis of colorectal cancer by sponging miR-512-3p	25
Downregulation of long non-coding RNA LINC00460 inhibits the proliferation, migration and invasion, and promotes apoptosis of pancreatic cancer cells via modulation of the miR-320b/ARF1 axis	25
MicroRNA-1269b inhibits gastric cancer development through regulating methyltransferase-like 3 (METTL3)	25
Firmicutes and Blautia in gut microbiota lessened in chronic liver diseases and hepatocellular carcinoma patients: a pilot study	25
Circular RNA UBAP2 facilitates the cisplatin resistance of triple-negative breast cancer via microRNA-300/anti-silencing function 1B histone chaperone/PI3K/AKT/mTOR axis	25
Ligustrazine induces viability, suppresses apoptosis and autophagy of retinal ganglion cells with ischemia/reperfusion injury through the PI3K/Akt/mTOR signaling pathway	25
Berberine inhibited carotid atherosclerosis through PI3K/AKTmTOR signaling pathway	25
Astragalus polysaccharide improve the proliferation and insulin secretion of mouse pancreatic β cells induced by high glucose and palmitic acid partially through promoting miR-136-5p and miR-149-5p ex	25
MicroRNA miR-146a-5p inhibits the inflammatory response and injury of airway epithelial cells via targeting TNF receptor-associated factor 6	25
The association between hypertension and nonalcoholic fatty liver disease (NAFLD): literature evidence and systems biology analysis	25
Long non-coding RNA ADAMTS9-AS1 attenuates ferroptosis by Targeting microRNA-587/solute carrier family 7 member 11 axis in epithelial ovarian cancer	25
Inhibition of micro RNA miR-122-5p prevents lipopolysaccharide-induced myocardial injury by inhibiting oxidative stress, inflammation and apoptosis via targeting GIT1	25
Long non-coding RNA LINC00511 regulates the expression of microRNA-625-5p and activates signal transducers and activators of transcription 3 (STAT3) to accelerate the progression of gastric cancer	24
Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis	24
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1	24
LncRNA DARS-AS1 aggravates the growth and metastasis of hepatocellular carcinoma via regulating the miR-3200-5p-Cytoskeleton associated protein 2 (CKAP2) axis	24
Exosomal microRNA⁃93⁃3p secreted by bone marrow mesenchymal stem cells downregulates apoptotic peptidase activating factor 1 to promote wound healing	24
Tumor-associated neutrophils activated by tumor-derived CCL20 (C-C motif chemokine ligand 20) promote T cell immunosuppression via programmed death-ligand 1 (PD-L1) in breast cancer	24
Clinical significance and potential molecular mechanism of miRNA-222-3p in metastatic prostate cancer	24
Microbial succession of lignocellulose degrading bacteria during composting of corn stalk	24
Shikonin induces apoptosis and autophagy via downregulation of pyrroline-5-carboxylate reductase1 in hepatocellular carcinoma cells	24
Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice	24
Long non-coding RNA histone deacetylase 4 antisense RNA 1 (HDAC4-AS1) inhibits HDAC4 expression in human ARPE-19 cells with hypoxic stress	24
N6-methyladenosine reader YTH N6-methyladenosine RNA binding protein 3 or insulin like growth factor 2 mRNA binding protein 2 knockdown protects human bronchial epithelial cells from hypoxia/reoxygena	24
CircularRNA circ_0071269 knockdown protects against from diabetic cardiomyopathy injury by microRNA-145/gasdermin A axis	24
Long non-coding RNA (lncRNA) PGM5P4-AS1 inhibits lung cancer progression by up-regulating leucine zipper tumor suppressor (LZTS3) through sponging microRNA miR-1275	23
CRISPR–Cas9-based genetic engineering for crop improvement under drought stress	23
Role of exosomal competitive endogenous RNA (ceRNA) in diagnosis and treatment of malignant tumors	23
The effect of N6-methyladenosine (m6A) factors on the development of acute respiratory distress syndrome in the mouse model	23
Exploration of the mechanism of luteolin against ischemic stroke based on network pharmacology, molecular docking and experimental verification	23
MicroRNA miR-145-5p inhibits Phospholipase D 5 (PLD5) to downregulate cell proliferation and metastasis to mitigate prostate cancer	23
Circular RNA_0062582 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via regulation of microRNA-145/CBFB axis	23
Ginsenoside-Rg3 inhibits the proliferation and invasion of hepatoma carcinoma cells via regulating long non-coding RNA HOX antisense intergenic	23
MicroRNA-25-3p promotes cisplatin resistance in Non-small-cell lung carcinoma (NSCLC) through adjusting PTEN/PI3K/AKT route	23
Identification of hub genes in thyroid carcinoma to predict prognosis by integrated bioinformatics analysis	23
Knock-down of microRNA miR-556-5p increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via activating NLR family pyrin domain containing 3 (NLRP3)-mediated pyroptotic cell death	23
Chinese patent medicine for osteoporosis: a systematic review and meta-analysis	23
Multifaceted roles of CCL20 (C-C motif chemokine ligand 20): mechanisms and communication networks in breast cancer progression	23
LRG1 promotes hypoxia-induced cardiomyocyte apoptosis and autophagy by regulating hypoxia-inducible factor-1α	23
The screening of immune-related biomarkers for prognosis of lung adenocarcinoma	23
Data mining-based study of collagen type III alpha 1 (COL3A1) prognostic value and immune exploration in pan-cancer	23
Long non-coding RNA TTN antisense RNA 1 facilitates hepatocellular carcinoma progression via regulating miR-139-5p/SPOCK1 axis	22
Argon inhibits reactive oxygen species oxidative stress via the miR-21-mediated PDCD4/PTEN pathway to prevent myocardial ischemia/reperfusion injury	22
Bone mesenchymal stem cells-derived miR-223-3p-containing exosomes ameliorate lipopolysaccharide-induced acute uterine injury via interacting with endothelial progenitor cells	22
Protecting effect of emodin in experimental autoimmune encephalomyelitis mice by inhibiting microglia activation and inflammation via Myd88/PI3K/Akt/NF-κB signalling pathway	22
Long non-coding RNA BCAR4 aggravated proliferation and migration in esophageal squamous cell carcinoma by negatively regulating p53/p21 signaling pathway	22
MicroRNA miR-874-3p inhibits osteoporosis by targeting leptin (LEP)	22
Mechanisms of Dendrobium officinale polysaccharides in repairing gastric mucosal injuries based on mitogen-activated protein kinases (MAPK) signaling pathway	22
Blood cell-derived extracellular vesicles: diagnostic biomarkers and smart delivery systems	22
Circular RNA Pvt1 oncogene (CircPVT1) promotes the progression of papillary thyroid carcinoma by activating the Wnt/β-catenin signaling pathway and modulating the ratio of microRNA-195 (miR-195) to va	22
Circular RNA circ_0090231 promotes atherosclerosis in vitro by enhancing NLR family pyrin domain containing 3-mediated pyroptosis of endothelial cells	22
Genetic modifications associated with sustainability aspects for sustainable developments	22
MicroRNA-21 regulate the cell apoptosis and cell proliferation of polycystic ovary syndrome (PCOS) granulosa cells through target toll like receptor TLR8	22
Study on the effect of synergy effect between the mixed cultures on the power generation of microbial fuel cells	22
MicroRNA-487a-3p inhibits the growth and invasiveness of oral squamous cell carcinoma by targeting PPM1A	22
Circular RNA Rbms1 inhibited the development of myocardial ischemia reperfusion injury by regulating miR-92a/BCL2L11 signaling pathway	22
Pinocembrin suppresses proliferation and enhances apoptosis in lung cancer cells in vitro by restraining autophagy	22
Circular RNA circCRKL inhibits the proliferation of acute myeloid leukemia cells via the miR-196a-5p/miR-196b-5p/p27 axis	22
Curcumin protection against ultraviolet-induced photo-damage in Hacat cells by regulating nuclear factor erythroid 2-related factor 2	22
Prediction of bladder cancer outcome by identifying and validating a mutation-derived genomic instability-associated long noncoding RNA (lncRNA) signature	21
Apigenin analogues as SARS-CoV-2 main protease inhibitors: In-silico screening approach	21
Circular RNA circ_0008274 upregulates granulin to promote the progression of hepatocellular carcinoma via sponging microRNA -140-3p	21
Circular RNA HIPK3 aggravates sepsis-induced acute kidney injury via modulating the microRNA-338/forkhead box A1 axis	21
Gastrodin attenuates perfluorooctanoic acid-induced liver injury by regulating gut microbiota composition in mice	21
G protein-coupled receptor 39 activation alleviates oxidized low-density lipoprotein-induced macrophage inflammatory response, lipid accumulation and apoptosis by inducing A20 expression	21
Knockdown of lncRNA PCAT6 suppresses the growth of non-small cell lung cancer cells by inhibiting macrophages M2 polarization via miR-326/KLF1 axis	21
Identification and validation of a five-lncRNA signature for predicting survival with targeted drug candidates in ovarian cancer	21
Long non-coding RNA DUXAP8 promotes the cell proliferation, migration, and invasion of papillary thyroid carcinoma via miR-223-3p mediated regulation of CXCR4	21
MiR-1224-5p attenuates polycystic ovary syndrome through inhibiting NOD-like receptor protein 3 inflammasome activation via targeting Forkhead box O 1	21
LncRNA SNHG1 promotes tumor progression and cisplatin resistance through epigenetically silencing miR-381 in breast cancer	21
Long intergenic non-protein coding RNA 1273 confers sorafenib resistance in hepatocellular carcinoma via regulation of methyltransferase 3	21
Comprehensive analysis of lncRNA-miRNA-mRNA regulatory networks for microbiota-mediated colorectal cancer associated with immune cell infiltration	21
Curcumin induces apoptosis and autophagy inhuman renal cell carcinoma cells via Akt/mTOR suppression	21
Circular RNA PLCE1 promotes epithelial mesenchymal transformation, glycolysis in colorectal cancer and M2 polarization of tumor-associated macrophages	21
Phosphorus recovery from wastewater and bio-based waste: an overview	21
Baicalin suppresses lung cancer growth phenotypes via miR-340-5p/NET1 axis	21
Long noncoding RNA small nucleolar RNA host gene 12/microRNA-138-5p/nuclear factor I/B regulates neuronal apoptosis, inflammatory response, and oxidative stress in Parkinson’s disease	21
Cyanidin-3-o-glucoside (C3G) inhibits vascular leakage regulated by microglial activation in early diabetic retinopathy and neovascularization in advanced diabetic retinopathy	21
Long non-coding RNA MEG3 inhibits neovascularization in diabetic retinopathy by regulating microRNA miR-6720-5p and cytochrome B5 reductase 2	21
The role of telomerase reverse transcriptase (TERT) promoter mutations in prognosis in bladder cancer	21
Bioprospecting of gut microflora for plastic biodegradation	21
LncRNA miR-17-92a-1 cluster host gene (MIR17HG) promotes neuronal damage and microglial activation by targeting the microRNA-153-3p/alpha-synuclein axis in Parkinson’s disease	21
Long non-coding RNA SOX21-AS1 modulates lung cancer progress upon microRNA miR-24-3p/PIM2 axis	21
α-Actinin1 promotes tumorigenesis and epithelial-mesenchymal transition of gastric cancer via the AKT/GSK3β/β-Catenin pathway	20