Molecular Therapy-Nucleic Acids

Papers
(The TQCC of Molecular Therapy-Nucleic Acids is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Characterization of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma to Aid Immunotherapy185
Immune-Related lncRNA to Construct Novel Signature and Predict the Immune Landscape of Human Hepatocellular Carcinoma151
m6A-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with LUAD145
Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer118
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis114
An Interpretable Prediction Model for Identifying N7-Methylguanosine Sites Based on XGBoost and SHAP109
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury101
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression99
Exosomes derived from miR-188-3p-modified adipose-derived mesenchymal stem cells protect Parkinson’s disease93
M2 Macrophage-Derived Exosomal lncRNA AFAP1-AS1 and MicroRNA-26a Affect Cell Migration and Metastasis in Esophageal Cancer92
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis91
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration91
Circular RNA: an important player with multiple facets to regulate its parental gene expression89
Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling77
Oncogenic Role of Long Noncoding RNAMALAT1 in Thyroid Cancer Progression through Regulation of the miR-204/IGF2BP2/m6A-MYC Signaling72
Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway71
m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression67
Artificial intelligence for drug discovery: Resources, methods, and applications66
Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer66
Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression64
MSC-Derived Exosomes Protect Vertebral Endplate Chondrocytes against Apoptosis and Calcification via the miR-31-5p/ATF6 Axis64
ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss62
DeepACP: A Novel Computational Approach for Accurate Identification of Anticancer Peptides by Deep Learning Algorithm60
The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases60
A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-259
miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review58
LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics57
lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment57
hsa_circ_0001955 Enhances In Vitro Proliferation, Migration, and Invasion of HCC Cells through miR-145-5p/NRAS Axis57
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and transcriptional activities of ECs in CC57
Epigenetics: Roles and therapeutic implications of non-coding RNA modifications in human cancers56
Cell death pathways and viruses: Role of microRNAs56
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A356
RETRACTED: YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner55
Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia55
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein55
Role of circRNA-miRNA-mRNA interaction network in diabetes and its associated complications52
Exosome-transmitted miRNA-335-5p promotes colorectal cancer invasion and metastasis by facilitating EMT via targeting RASA152
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis52
The role of M6A modification in the regulation of tumor-related lncRNAs52
Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer51
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways51
Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC50
Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks49
RETRACTED: METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung49
Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC48
Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes48
Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance47
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin47
Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL46
Mesenchymal stem-cell-derived exosomal miR-145 inhibits atherosclerosis by targeting JAM-A46
DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome45
Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells45
Targeting the epigenome in in-stent restenosis: from mechanisms to therapy44
Circular RNA circTMEM45A Acts as the Sponge of MicroRNA-665 to Promote Hepatocellular Carcinoma Progression44
Circular RNA circCUL3 Accelerates the Warburg Effect Progression of Gastric Cancer through Regulating the STAT3/HK2 Axis44
Microfluidics for detection of exosomes and microRNAs in cancer: State of the art44
circRNA CDR1as Promotes Pulmonary Artery Smooth Muscle Cell Calcification by Upregulating CAMK2D and CNN3 via Sponging miR-7-5p44
ncRNAs-mediated high expression of SEMA3F correlates with poor prognosis and tumor immune infiltration of hepatocellular carcinoma44
lncRNA SNHG10 Promotes the Proliferation and Invasion of Osteosarcoma via Wnt/β-Catenin Signaling43
Exosomal Long Non-coding RNAs: Emerging Players in the Tumor Microenvironment43
Inhibition of Zika virus replication by G-quadruplex-binding ligands43
Regulatory roles of tRNA-derived RNA fragments in human pathophysiology43
Engineering highly efficient backsplicing and translation of synthetic circRNAs43
METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway42
miR-204 silencing reduces mitochondrial autophagy and ROS production in a murine AD model via the TRPML1-activated STAT3 pathway42
Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells42
LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer41
Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs41
An immunogenomic signature for molecular classification in hepatocellular carcinoma40
Empirical Comparison and Analysis of Web-Based DNA N4-Methylcytosine Site Prediction Tools40
Emerging roles of circRNAs in the pathological process of myocardial infarction40
Synovial Mesenchymal Stem Cell-Derived EV-Packaged miR-31 Downregulates Histone Demethylase KDM2A to Prevent Knee Osteoarthritis40
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression40
miR-223-3p as a potential biomarker and player for adipose tissue dysfunction preceding type 2 diabetes onset39
miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer39
FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway38
Biological roles and therapeutic potential of circular RNAs in osteoarthritis38
The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration38
METTL14 Gene Polymorphisms Confer Neuroblastoma Susceptibility: An Eight-Center Case-Control Study38
circRNA circARNT2 Suppressed the Sensitivity of Hepatocellular Carcinoma Cells to Cisplatin by Targeting the miR-155-5p/PDK1 Axis38
SMC1A regulated by KIAA1429 in m6A-independent manner promotes EMT progress in breast cancer37
circGNAQ, a circular RNA enriched in vascular endothelium, inhibits endothelial cell senescence and atherosclerosis progression36
Notochordal-Cell-Derived Exosomes Induced by Compressive Load Inhibit Angiogenesis via the miR-140-5p/Wnt/β-Catenin Axis36
Long noncoding RNA Cfast regulates cardiac fibrosis36
miR-150-Based RNA Interference Attenuates Tubulointerstitial Fibrosis through the SOCS1/JAK/STAT Pathway In Vivo and In Vitro36
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B36
Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer36
Circular RNA: A potential diagnostic, prognostic, and therapeutic biomarker for human triple-negative breast cancer35
Comprehensive analysis to identify DLEU2L/TAOK1 axis as a prognostic biomarker in hepatocellular carcinoma35
The Circular RNA-miRNA Axis: A Special RNA Signature Regulatory Transcriptome as a Potential Biomarker for OSCC35
miR-144 delivered by nasopharyngeal carcinoma-derived EVs stimulates angiogenesis through the FBXW7/HIF-1α/VEGF-A axis35
CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells35
Rationale and strategies for the development of safe and effective optimized AAV vectors for human gene therapy35
METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination35
Placental trophoblast cell-derived exosomal microRNA-1290 promotes the interaction between endometrium and embryo by targeting LHX635
Biological Implications and Clinical Potential of Metastasis-Related miRNA in Colorectal Cancer34
Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture34
Therapeutic potential and recent advances on targeting mitochondrial dynamics in cardiac hypertrophy: A concise review34
lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep34
HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing34
miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways34
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease34
Silencing of lncRNA XIST impairs angiogenesis and exacerbates cerebral vascular injury after ischemic stroke33
Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer33
Exosomal LINC00174 derived from vascular endothelial cells attenuates myocardial I/R injury via p53-mediated autophagy and apoptosis33
Base-modified aptamers obtained by cell-internalization SELEX facilitate cellular uptake of an antisense oligonucleotide33
Cathepsin B deteriorates diabetic cardiomyopathy induced by streptozotocin via promoting NLRP3-mediated pyroptosis33
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation32
Development of an mRNA replacement therapy for phenylketonuria32
TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer32
Upregulation of long non-coding RNA SNHG16 promotes diabetes-related RMEC dysfunction via activating NF-κB and PI3K/AKT pathways32
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway32
5′-tiRNA-Cys-GCA regulates VSMC proliferation and phenotypic transition by targeting STAT4 in aortic dissection32
Comprehensive analysis of N6-methylandenosine regulators and m6A-related RNAs as prognosis factors in colorectal cancer32
Hypoxic ucMSC-secreted exosomal miR-125b promotes endothelial cell survival and migration during wound healing by targeting TP53INP132
circRNA hsa_circ_0018414 inhibits the progression of LUAD by sponging miR-6807-3p and upregulating DKK131
miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway31
Gene therapy to enhance angiogenesis in chronic wounds31
Preeclampsia-Associated lncRNA INHBA-AS1 Regulates the Proliferation, Invasion, and Migration of Placental Trophoblast Cells31
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway31
First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers31
Double-stranded RNA reduction by chaotropic agents during in vitro transcription of messenger RNA31
LINC-PINT Suppresses the Aggressiveness of Thyroid Cancer by Downregulating miR-767-5p to Induce TET2 Expression31
circFOXM1 contributes to sorafenib resistance of hepatocellular carcinoma cells by regulating MECP2 via miR-132431
LINC00857 Interacting with YBX1 to Regulate Apoptosis and Autophagy via MET and Phosphor-AMPKa Signaling31
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation31
Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages31
Recent research progress on circular RNAs: Biogenesis, properties, functions, and therapeutic potential30
GC-Derived EVs Enriched with MicroRNA-675-3p Contribute to the MAPK/PD-L1-Mediated Tumor Immune Escape by Targeting CXXC430
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes30
Long non-coding RNA linc00665 inhibits CDKN1C expression by binding to EZH2 and affects cisplatin sensitivity of NSCLC cells30
Genomic analysis uncovers prognostic and immunogenic characteristics of ferroptosis for clear cell renal cell carcinoma29
Müller glia-derived exosomal miR-9-3p promotes angiogenesis by restricting sphingosine-1-phosphate receptor S1P1 in diabetic retinopathy29
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis29
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination29
Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis29
MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK29
Gain of Function of Ion Channel TRPV1 Exacerbates Experimental Colitis by Promoting Dendritic Cell Activation29
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis29
Smart exosomes with lymph node homing and immune-amplifying capacities for enhanced immunotherapy of metastatic breast cancer29
circEYA1 Functions as a Sponge of miR-582-3p to Suppress Cervical Adenocarcinoma Tumorigenesis via Upregulating CXCL1429
D614G mutation eventuates in all VOI and VOC in SARS-CoV-2: Is it part of the positive selection pioneered by Darwin?29
Combining an optimized mRNA template with a double purification process allows strong expression of in vitro transcribed mRNA29
miR-21 mimic blocks obesity in mice: A novel therapeutic option29
NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients29
CircHGF suppressed cell proliferation and osteogenic differentiation of BMSCs in ONFH via inhibiting miR-25-3p binding to SMAD729
circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression29
Association of clock-like mutational signature with immune checkpoint inhibitor outcome in patients with melanoma and NSCLC29
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer28
Regulation of pyroptosis in cardiovascular pathologies: Role of noncoding RNAs28
Mechanisms of NAT10 as ac4C writer in diseases28
Neutrophil-like cell membrane-coated siRNA of lncRNA AABR07017145.1 therapy for cardiac hypertrophy via inhibiting ferroptosis of CMECs28
Autophagy in cardiovascular diseases: role of noncoding RNAs28
circFLT1 and lncCCPG1 Sponges miR-93 to Regulate the Proliferation and Differentiation of Adipocytes by Promoting lncSLC30A9 Expression28
Intratumoral delivered novel circular mRNA encoding cytokines for immune modulation and cancer therapy28
Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates28
Cardiomyocyte mitochondrial dynamic-related lncRNA 1 (CMDL-1) may serve as a potential therapeutic target in doxorubicin cardiotoxicity28
Osteoclast-derived small extracellular vesicles induce osteogenic differentiation via inhibiting ARHGAP128
Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information28
lncRNA MIR210HG promotes the progression of endometrial cancer by sponging miR-337-3p/137 via the HMGA2-TGF-β/Wnt pathway28
Non-coding RNA basis of muscle atrophy28
The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease28
lncRNA GAS6-AS1 inhibits progression and glucose metabolism reprogramming in LUAD via repressing E2F1-mediated transcription of GLUT127
Hepatocyte-derived exosomal miR-27a activates hepatic stellate cells through the inhibition of PINK1-mediated mitophagy in MAFLD27
Circular RNA circRIMS1 Acts as a Sponge of miR-433-3p to Promote Bladder Cancer Progression by Regulating CCAR1 Expression27
Exosome-derived noncoding RNAs: Function, mechanism, and application in tumor angiogenesis27
CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs27
Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis27
m5UPred: A Web Server for the Prediction of RNA 5-Methyluridine Sites from Sequences27
miR-181a, delivered by hypoxic PTC-secreted exosomes, inhibits DACT2 by downregulating MLL3, leading to YAP-VEGF-mediated angiogenesis27
Effects of long-term culture on the biological characteristics and RNA profiles of human bone-marrow-derived mesenchymal stem cells26
LINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway26
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner26
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay26
Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescence26
CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma26
Internal m7G methylation: A novel epitranscriptomic contributor in brain development and diseases25
DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer25
Novel insights into the interaction between N6-methyladenosine modification and circular RNA25
Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction25
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT125
Naringin improves sepsis-induced intestinal injury by modulating macrophage polarization via PPARγ/miR-21 axis25
Recent advances in crosstalk between N6-methyladenosine (m6A) modification and circular RNAs in cancer25
mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD25
STAT3-Induced lncRNA SNHG17 Exerts Oncogenic Effects on Ovarian Cancer through Regulating CDK625
ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis24
LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/αvβ3 integrin/FAK-MAPK axis in ICC24
RETRACTED: miR-146a inhibits mitochondrial dysfunction and myocardial infarction by targeting cyclophilin D24
hsa_circNFXL1_009 modulates apoptosis, proliferation, migration, and potassium channel activation in pulmonary hypertension24
Cancer immunomodulation using bispecific aptamers24
Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss24
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS24
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy24
lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX1224
The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by binding polyadenylate-binding protein 2 to stabilize SREBP1 mRNA24
Genetic or siRNA inhibition of MBD2 attenuates the UUO- and I/R-induced renal fibrosis via downregulation of EGR124
A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA202024
lncRNA HotairM1 Depletion Promotes Self-Renewal of Cancer Stem Cells through HOXA1-Nanog Regulation Loop24
Transfer of microRNA-25 by colorectal cancer cell-derived extracellular vesicles facilitates colorectal cancer development and metastasis24
Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits24
MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-466023
Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway23
Preclinical evaluation of WVE-004, an investigational stereopure oligonucleotide for the treatment of C9orf72-associated ALS or FTD23
Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis23
miR-27a-3p Targets ATF3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells23
ATF2-Induced lncRNA GAS8-AS1 Promotes Autophagy of Thyroid Cancer Cells by Targeting the miR-187-3p/ATG5 and miR-1343-3p/ATG7 Axes23
KLF5-Modulated lncRNA NEAT1 Contributes to Tumorigenesis by Acting as a Scaffold for BRG1 to Silence GADD45A in Gastric Cancer23
Long non-coding RNA lnc-CCNL1-3:1 promotes granulosa cell apoptosis and suppresses glucose uptake in women with polycystic ovary syndrome23
Circular RNAs in prostate cancer: Biogenesis, biological functions, and clinical significance23
Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription23
miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI23
circNR3C1 Suppresses Bladder Cancer Progression through Acting as an Endogenous Blocker of BRD4/C-myc Complex23
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis22
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering22
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells22
Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK122
CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling22
Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer22
HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer22
miR-940 is a new biomarker with tumor diagnostic and prognostic value22
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP122
Yeast microcapsule-mediated oral delivery of IL-1β shRNA for post-traumatic osteoarthritis therapy22
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia22
The role of non-coding RNAs in chemotherapy for gastrointestinal cancers22
MicroRNA-22 Inhibits the Apoptosis of Vascular Smooth Muscle Cell by Targeting p38MAPKα in Vascular Remodeling of Aortic Dissection22
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders22
RETRACTED: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma22
Circular RNA in tumor metastasis22
Rise of TRIM8: A Molecule of Duality22
Cytidine-containing tails robustly enhance and prolong protein production of synthetic mRNA in cell and in vivo22
LINC01094 promotes pancreatic cancer progression by sponging miR-577 to regulate LIN28B expression and the PI3K/AKT pathway22
The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis21
A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice21
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC21
A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting TRPA121
Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs21
RETRACTED: MTTL3 upregulates microRNA-1246 to promote occurrence and progression of NSCLC via targeting paternally expressed gene 321
MicroRNA-3613-5p Promotes Lung Adenocarcinoma Cell Proliferation through a RELA and AKT/MAPK Positive Feedback Loop21
Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations21
RETRACTED: m6A demethylase FTO suppresses pancreatic cancer tumorigenesis by demethylating PJA2 and inhibiting Wnt signaling21
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b21
ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment21
Emerging roles of circular RNAs in systemic lupus erythematosus21
The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy21
CircRNA Chordc1 protects mice from abdominal aortic aneurysm by contributing to the phenotype and growth of vascular smooth muscle cells21
Heterogeneity of human corneal endothelium implicates lncRNA NEAT1 in Fuchs endothelial corneal dystrophy21
Dual effects of N6-methyladenosine on cancer progression and immunotherapy21
Serum lncRNAs in early pregnancy as potential biomarkers for the prediction of pregnancy-induced hypertension, including preeclampsia21
Essential role of ALKBH5-mediated RNA demethylation modification in bile acid-induced gastric intestinal metaplasia20
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