Molecular Therapy-Nucleic Acids

Papers
(The TQCC of Molecular Therapy-Nucleic Acids is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Effective intravitreal gene delivery to retinal pigment epithelium with hyaluronic acid nanospheres215
Novel eRF3a degrader enhances gentamicin-induced premature termination codon readthrough in epidermolysis bullosa119
Forced enhancer-promoter rewiring to alter gene expression in animal models111
Comparison of MALAT1 antisense oligonucleotide distribution following intracerebroventricular and lumbar intrathecal routes of administration106
All roads lead to cure: Diversity of oligonucleotides in DM1 therapy101
Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells89
AAV-vectored base editor trans-splicing delivers dystrophin repair87
LinQURE: A novel AAV gene silencing platform that supports multi-transcript targeting for complex disorders86
An oversized AAV8 vector to deliver CPS183
Insights into the regulatory role of epigenetics in moyamoya disease: Current advances and future prospectives82
SPRINGing forward: Advancing RNA editing efficiency and precision with engineered ADAR274
cncFinder: A graph-attention-network-based interpretable learning model to identify bifunctional long non-coding RNAs73
Seeking stability for gene addition in inborn errors of metabolism72
Using RNA-targeting CRISPR-Cas13 and engineered U1 systems to target ABCA4 splice variants in Stargardt disease72
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells69
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease68
Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion63
Retraction Notice to: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma63
Unlocking RNA mysteries: Predicting subcellular localizations with AI61
A novel gene therapy platform for the treatment of type 2 diabetes and obesity61
Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation59
Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 158
MicroRNA-466 and microRNA-200 increase endothelial permeability in hyperglycemia by targeting Claudin-558
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling58
Inefficacy of anti-VEGF therapy reflected in VEGF-mediated photoreceptor degeneration57
Base editing strategies for in vivo correction of two highly recurrent phenylketonuria variants55
Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjӧgren’s syndrome55
Single-swap editing for the correction of common Duchenne muscular dystrophy mutations54
Enhanced molecular dynamic simulation studies unravel long-range effects caused by sequence variations and partner binding in RNA aptamers52
Durable HTT silencing using non-evolved dCas9 epigenome editors in patient-derived cells51
DUX4 reduction and muscle function improvement by subcutaneous delivery of gapmer antisense oligonucleotides51
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer50
Progress and prospect of minicircle as a minimized non-viral DNA vector in gene therapy and regenerative medicine49
Alleviation of ischemia-reperfusion induced renal injury by chemically modified SOD2 mRNA delivered via lipid nanoparticles49
Modulation of miR-29 influences myocardial compliance likely through coordinated regulation of calcium handling and extracellular matrix49
Single-cell transcriptome profiling implicates the psychological stress-induced disruption of spermatogenesis49
Implications of circular transcripts in DM1 pathomechanism47
A potent GalNAc-siRNA drug, RBD1016, leads to sustained HBsAg reduction and seroconversion in mouse models of HBV infection47
Ferroptosis as a therapeutic target in glioblastoma: Mechanisms and emerging strategies47
Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models46
Joint masking and self-supervised strategies for inferring small molecule-miRNA associations46
Recent advances in CRISPR-Cas9-based genome insertion technologies46
Topical application of a CCL22-binding aptamer suppresses contact allergy45
Change of intracellular calcium level causes acute neurotoxicity by antisense oligonucleotides via CSF route44
Discovery of peptides for ligand-mediated delivery of mRNA lipid nanoparticles to cystic fibrosis lung epithelia44
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways44
Non-uniform dystrophin re-expression after CRISPR-mediated exon excision in the dystrophin/utrophin double-knockout mouse model of DMD43
Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling43
Right on target: The next class of efficient, safe, and specific RNAi triggers42
PPFIA1-targeting miR-181a mimic and saRNA overcome imatinib resistance in BCR-ABL1-independent chronic myeloid leukemia by suppressing leukemia stem cell regeneration42
Structural variants and modifications of hammerhead ribozymes targeting influenza A virus conserved structural motifs41
Double-stranded RNA induction asa potential dynamic biomarkerfor DNA-demethylating agents40
Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency40
Rapid molecular imaging of active thrombi in vivo using aptamer-antidote probes39
Extracellular viral microRNAs as biomarkers of virus infection in human cells39
Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP738
Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss38
Engineering B cells with customized therapeutic responses using a synthetic circuit38
tRF-1001: A potential therapeutic target for ocular neovascular diseases38
DNA-PKcs inhibition improves sequential gene insertion of the full-length CFTR cDNA in airway stem cells37
Unlocking the therapeutic potential of locked nucleic acids through lipid nanoparticle delivery37
miR-204 suppresses cancer stemness and enhances osimertinib sensitivity in non-small cell lung cancer by targeting CD4437
Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer37
A conditional RNA Pol II mono-promoter drives HIV-inducible, CRISPR-mediated cyclin T1 suppression and HIV inhibition36
Antitumor effects of chemically modified miR-143 lipoplexes in a mouse model of pelvic colorectal cancer via myristoylated alanine-rich C kinase substrate downregulation36
Nucleic acid delivery for pathology treatment: RNA tissue delivery36
Effect of degeneration stage on non-viral tissue transfection of rd10 retina ex vivo35
CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA35
A genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma35
Improved cross-protection and immunity against influenza A virus in mice using a novel mRNA vaccine with optimized design of RNA sequence35
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin34
DNA electroporation in a vacuum: A “shocking” innovation for vaccines34
RNA therapeutics in targeting G protein-coupled receptors: Recent advances and challenges34
Off-target effects in CRISPR-Cas genome editing for human therapeutics: Progress and challenges34
Targeting microRNA-145-mediated progressive phenotypes of early bladder cancer in a molecularly defined in vivo model34
Block or degrade? Balancing on- and off-target effects of antisense strategies against transcripts with expanded triplet repeats in DM133
Lung transcriptome of nonhuman primates exposed to total- and partial-body irradiation33
Combining independent protein and cellular SELEX with bioinformatic analysis may allow high affinity aptamer hit discovery33
miR-342-5p downstream to Notch enhances arterialization of endothelial cells in response to shear stress by repressing MYC33
Targeting ZC3H11A elicits immunogenic cancer cell death through augmentation of antigen presentation and interferon response32
PPM1H is down-regulated by ATF6 and dephosphorylates p-RPS6KB1 to inhibit progression of hepatocellular carcinoma32
The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders32
Retraction Notice to: Oncogenic miR-27a delivered by exosomes binds to SFRP1 and promotes angiogenesis in renal clear cell carcinoma32
TREX2 enables efficient genome disruption mediated by paired CRISPR-Cas9 nickases that generate 3′-overhanging ends31
Gene therapy to enhance angiogenesis in chronic wounds31
Palmitoyl transferases act as potential regulators of tumor-infiltrating immune cells and glioma progression31
Dynamic regulation of NeuroD1 expression level by a novel viral construct during astrocyte-to-neuron reprogramming31
Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant HTT31
Expanding RNA editing toolkit using an IDR-based strategy31
Expanding DdCBE-mediated targeting scope to aC motif preference in rat30
Single-cell transcriptomics of multi-site cell therapy in osteoarthritis: Tissue-specific treatment correlations30
Epigenetic regulation of MIR145 core promoter controls miR-143/145 cluster in bladder cancer progression and treatment outcome30
Targeting oncogenic KRAS in non-small cell lung cancer with EGFR aptamer-conjugated multifunctional RNA nanoparticles30
miR-363 Alleviates Detrusor Fibrosis via the TGF-β1/Smad Signaling Pathway by Targeting Col1a2 in Rat Models of STZ-Induced T2DM30
Nimbolide-based nanomedicine inhibits breast cancer stem-like cells by epigenetic reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling axis30
Gymnotic uptake of AntimiRs alter microRNA-34a levels in 2D and 3D epithelial cell culture30
Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models30
Precise template-free correction restores gene function in Tay-Sachs disease while reframing is ineffective30
SHMT2 is essential for mammalian preimplantation embryonic development through de novo biosynthesis of nucleotide metabolites30
Multispecies-targeting siRNAs for the modulation of JAK1 in the skin30
MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4BDCAF13 E3 Ligase in Osteosarcoma Cells29
Enhanced hammerhead ribozyme turnover rates: Reevaluating therapeutic space for small catalytic RNAs29
Molecular treatment options for patients carrying KIAA0586/TALPID3 variants29
In vivo precision base editing to rescue mouse models of disease29
Multi-omics integrative analysis reveals novel genetic loci and candidate genes for ischemic stroke29
Turning premature stop codons into therapeutic opportunities29
mRNA therapeutics: Transforming medicine through innovation in design, delivery, and disease treatment28
Realizing the therapeutic potential of rapid knockdown of transthyretin via RNA interference in transthyretin amyloidosis28
Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways28
Hepatic-stellate-cell-targeted delivery of PU.1 decoy ODN by Apt-Tan attenuates liver fibrosis in mice28
Identification and characterization of a MAPT-targeting locked nucleic acid antisense oligonucleotide therapeutic for tauopathies28
A proximity-labeling-based approach to directly detect mRNA delivery to specific subcellular locations28
MicroRNA Profiling in Paired Left and Right Eyes, Lungs, and Testes of Normal Mice27
Testis electroporation coupled with autophagy inhibitor to treat non-obstructive azoospermia27
An important resource and analytic platform for human and mouse cardiovascular-related cis-regulatory elements27
Engineering miniature CRISPR-Cas Un1Cas12f1 for efficient base editing27
Local intraluminal delivery of a smooth muscle-targeted RNA ligand inhibits neointima growth in a porcine model of peripheral vascular disease27
MiR-34 at the crossroads of SMA pathogenesis and therapy: Emerging biomarker and therapeutic target26
Optimized allele-specific silencing of the dominant-negative COL6A1 G293R substitution causing collagen VI-related dystrophy26
Retraction Notice to: LncRNA LINC00963 Promotes Tumorigenesis and Radioresistance in Breast Cancer by Sponging miR-324-3p and Inducing ACK1 Expression26
mRNA-encoded ACE2 decoy lipid nanoparticles for neutralizing SARS-CoV-2 variants26
Use of an oversized AAV8 vector for CPS1 deficiency results in long-term survival and ammonia control26
Delivery of therapeutic small interfering RNA: The current patent-based landscape26
Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells25
An acyclic nucleic acid-modified siRNA targeting CAG expansions for polyglutamine disease treatment25
Polymeric nanoparticle-based mRNA vaccine is protective against influenza virus infection in ferrets25
Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA25
Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity25
Lipid self-assembling nanoparticles as a novel platform for mRNA-based vaccination25
Non-cytolytic re-engineering of a viral vaccine vector enables durable effector-memory T cell immunity by reinforcing type I IFN induction25
Base editing corrects the common Salla disease SLC17A5 c.115C>T variant25
Improving cell and gene therapy safety and performance using next-generation Nanoplasmid vectors24
Unlocking mRNA-driven CRISPR-Cas9 gene therapy via optimizing mRNA and the delivery vectors24
CRISPR-Cas9 in hiPSCs: A new era in personalized treatment for Stargardt disease24
CRISPR-Cas9-mediated homology-directed repair for precise gene editing24
siRNA goes after diseases of the bone24
MVA-HBVac—A novel vaccine vector that allows pan-genotypic targeting of hepatitis B virus by therapeutic vaccination24
Behavioral improvement in dystrophic mdx23 mouse following repeated antisense oligonucleotides injections24
Rethinking CRISPR delivery for liver-targeted gene editing: The case for spatially fractionated intra-arterial approaches24
Visual function restoration in a mouse model of Leber congenital amaurosis via therapeutic base editing24
m6A-induced repression of SIAH1 facilitates alternative splicing of androgen receptor variant 7 by regulating CPSF124
A model system for antiviral siRNA therapeutics using exosome-based delivery23
Rational design and applications of piperazine and cyclohexane ionizable lipids for PKU and SSADH deficiency23
SINEUPs to boost translation23
Axl deficiency promotes preeclampsia and vascular malformations in mice23
Retraction Notice to: GLP2 Promotes Directed Differentiation from Osteosarcoma Cells to Osteoblasts and Inhibits Growth of Osteosarcoma Cells23
Retraction Notice to: Schizandrin A Protects Human Retinal Pigment Epithelial Cell Line ARPE-19 against HG-Induced Cell Injury by Regulation of miR-14523
Gene network landscape of mouse splenocytes reveals integrin complex as the A151 ODN-responsive hub molecule in the immune transcriptome23
Enhancing mRNA translation efficiency by introducing sequence optimized AU-rich elements in 3′ UTR via HuR anchorage23
Retraction Notice to: TNFAIP8 Promotes Cisplatin Chemoresistance in Triple-Negative Breast Cancer by Repressing p53-Mediated miR-205-5p Expression23
Direct delivery of Cas9 or base editor protein and guide RNA complex enables genome editing in the retina23
Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer23
Selection of DNA aptamers that prevent the fibrillization of α-synuclein protein in cellular and mouse models22
Modulation of miR-181 influences dopaminergic neuronal degeneration in a mouse model of Parkinson’s disease22
Lipid nanoparticle-encapsulated microRNA-192: An anti-inflammatory adjuvant that enhances vaccine efficacy in aged mice22
Development of versatile allele-specific siRNAs able to silence all the dominant dynamin 2 mutations22
Restoration of brain dystrophin using tricyclo-DNA ASOs restores neurobehavioral deficits in DMD mice22
Efficacy of exon-skipping therapy for DMD cardiomyopathy with mutations in actin binding domain 121
High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells21
FUBP3: A new player in HIV-1 transcriptional activation and immune regulation21
Unveiling the role of PUS7-mediated pseudouridylation in host protein interactions specific for the SARS-CoV-2 RNA genome21
Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice21
Dendritic siRNA conjugate riding albumin for targeted delivery to solid tumors20
Promising strategies employing nucleic acids as antimicrobial drugs20
Investigating adverse genomic and regulatory changes caused by replacement of the full-length CFTR cDNA using Cas9 and AAV20
An instructive attempt on developing aptamer-constructed PROTAC for breast cancer treatment20
Using muscle homing peptide CyPep10 to deliver phosphorodiamidate morpholino oligomers in the mdx mouse20
Human opsin restoration by histone methylation using methyltransferase fusion protein SETD7-dCas920
Engineering RsDddA as mitochondrial base editor with wide target compatibility and enhanced activity20
MicroRNA-378 contributes to osteoarthritis by regulating chondrocyte autophagy and bone marrow mesenchymal stem cell chondrogenesis20
Manipulating the delivery and immunogenicity of DNA vaccines through the addition of CB[8] to cationic polymers20
Advancements and challenges in mRNA and ribonucleoprotein-based therapies: From delivery systems to clinical applications20
Plug-and-play nucleic acid-mediated multimerization of biparatopic nanobodies for molecular imaging20
Pharmacoepitranscriptomic landscape revealing m6A modification could be a drug-effect biomarker for cancer treatment20
A potential therapeutic approach for tauopathies19
Opposing impacts of DNA polyplex crosslinking on delivery efficiency and vaccine responses19
Role of long non-coding RNAs in cancer: From subcellular localization to nanoparticle-mediated targeted regulation19
A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication19
Replication not required: mRNA vaccines take on non-enveloped viruses19
A fleeting glimpse of functional benefit of the complete DMD gene in a large animal model of Duchenne muscular dystrophy19
Royal jelly extracellular vesicles promote wound healing by modulating underlying cellular responses19
MiR-142a-3p: A novel ACh receptor transcriptional regulator in association with peripheral nerve injury19
Antisense oligonucleotide targeting nicotinamide N-methyltransferase exhibits antitumor effects19
Base editing in humanized dystrophic mice19
Retraction Notice to: Exosome miR-155 Derived from Gastric Carcinoma Promotes Angiogenesis by Targeting the c-MYB/VEGF Axis of Endothelial Cells19
Bile acid accumulation induced by miR-122 deficiency in liver parenchyma promotes cancer cell growth in hepatocellular carcinoma19
A lipid nanoparticle-based oligodendrocyte-specific mRNA therapy19
Cis-Cardio: A comprehensive analysis platform for cardiovascular-relavant cis-regulation in human and mouse19
Blood pressure reduction through brain delivery of nanoparticles loaded with plasmid DNA encoding angiotensin receptor shRNA19
A pipeline for identifying guide RNA sequences that promote RNA editing of nonsense mutations that cause inherited retinal diseases19
Adenovirus expressing nc886, an anti-interferon and anti-apoptotic non-coding RNA, is an improved gene delivery vector19
VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF19
Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage19
Partial restoration of brain dystrophin by tricyclo-DNA antisense oligonucleotides alleviates emotional deficits in mdx52 mice19
RNA activation of CEBPA improves leukemia treatment18
Restoration of myogenesis in ALS-myocytes through miR-26a-5p-mediated Smad4 inhibition and its impact on motor neuron development18
Recent applications, future perspectives, and limitations of the CRISPR-Cas system18
Unveiling the emerging functions of nuclear actin in gene function regulation18
Retraction Notice to: Overexpression of microRNA-203 Suppresses Proliferation, Invasion, and Migration while Accelerating Apoptosis of CSCC Cell Line SCL-118
Secondary follicles enable efficient germline mtDNA base editing at hard-to-edit site18
Oversized liposomes boost macrophage-targeted RNA delivery to regulate macrophage polarity18
Self-attention enabled deep learning of dihydrouridine (D) modification on mRNAs unveiled a distinct sequence signature from tRNAs18
Analytical approach for identification and mechanistic insights into mRNA-lipid adduct formation18
Subgenomic particles in rAAV vectors result from DNA lesion/break and non-homologous end joining of vector genomes18
Conjugated STING agonists18
Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents18
Long noncoding RNA LUCAT1 enhances the survival and therapeutic effects of mesenchymal stromal cells post-myocardial infarction18
Antisense oligonucleotide targeting the E3 ligase RFFL potentiates CFTR modulator efficacy in CF primary bronchial epithelial cells18
Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus18
Inducible miR-1224 silences cerebrovascular Serpine1 and restores blood flow to the stroke-affected site of the brain18
Delivering therapeutic RNA into the brain using extracellular vesicles18
Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection18
A cystic fibrosis gene editing approach that is on target18
mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection18
Retraction Notice to: MTTL3 upregulates microRNA-1246 to promote occurrence and progression of NSCLC via targeting paternally expressed gene 318
Base editing rescues acid α-glucosidase function in infantile-onset Pompe disease patient-derived cells18
Exon skipping induces uniform dystrophin rescue with dose-dependent restoration of serum miRNA biomarkers and muscle biophysical properties18
HIF-1α or HOTTIP/CTCF Promotes Head and Neck Squamous Cell Carcinoma Progression and Drug Resistance by Targeting HOXA917
Harnessing defective interfering particles and lipid nanoparticles for effective delivery of an anti-dengue virus RNA therapy17
Cell-penetrating antibody enhances nuclear delivery of triplex-forming oligonucleotides targeting HER2-positive cancers17
Translatomics to explore dynamic differences in immunocytes in the tumor microenvironment17
Exon 44 skipping in Duchenne muscular dystrophy: NS-089/NCNP-02, a dual-targeting antisense oligonucleotide17
EPRIM: An approach of identifying cancer immune-related epigenetic regulators17
Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs17
miR-429 RNA therapy as generic strategy to protect against photoreceptor loss17
Retraction Notice to: Circular RNA Profiling Reveals Exosomal circ_0006156 as a Novel Biomarker in Papillary Thyroid Cancer17
Engineered miR-122 inhibitors preserve endothelial mitochondrial function and prevent vascular dysfunction in obesity-associated prediabetes17
Gal-3 activates Tyro3 to ameliorate ferroptosis of hippocampal neurons after traumatic brain injury17
Targeted allele-specific FGFR2 knockdown via human recombinant ferritin nanoparticles for personalized treatment of Crouzon syndrome17
Lipopeptide-mediated Cas9 RNP delivery: A promising broad therapeutic strategy for safely removing deep-intronic variants in ABCA417
Engineering an adenine base editor in human embryonic stem cells with minimal DNA and RNA off-target activities17
Subretinal gene therapy delays vision loss in a Bardet-Biedl Syndrome type 10 mouse model17
Retraction Notice to: MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer17
Retraction Notice to: lncRNA MALAT1 Accelerates Wound Healing of Diabetic Mice Transfused with Modified Autologous Blood via the HIF-1α Signaling Pathway17
Splicing correction by peptide-conjugated morpholinos as a novel treatment for late-onset Pompe disease17
Toward learning the rules that predict siRNA efficacy17
cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice17
Rescue of the endogenous FVIII expression in hemophilia A mice using CRISPR-Cas9 mRNA LNPs17
MicroRNA-451a inhibits gemcitabine-refractory biliary tract cancer progression by suppressing the MIF-mediated PI3K/AKT pathway17
Cell-type-specific alternative polyadenylation as a therapeutic biomarker in lung cancer progression17
A shift of paradigm, emerging role of miRNAs as therapeutic targets for complex disease16
Retraction Notice to: Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling16
Apolipoprotein E and viral infection: Risks and Mechanisms16
miRNA-642a-3p protects β cells from glucolipotoxicity16
Upregulation of a CFTR mRNA isoform has therapeutic potential for the treatment of 3′ CFTR PTC variants16
Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype16
Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression16
Thank you to our 2023 reviewers16
Mechanosensitive calcium ion channels Piezo1: A therapeutic target in liver disease16
Genetic or siRNA inhibition of MBD2 attenuates the UUO- and I/R-induced renal fibrosis via downregulation of EGR116
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