Molecular Therapy-Nucleic Acids

Article	Citations
Characterization of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma to Aid Immunotherapy	185
Immune-Related lncRNA to Construct Novel Signature and Predict the Immune Landscape of Human Hepatocellular Carcinoma	151
m6A-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with LUAD	145
Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer	118
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis	114
An Interpretable Prediction Model for Identifying N7-Methylguanosine Sites Based on XGBoost and SHAP	109
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury	101
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression	99
Exosomes derived from miR-188-3p-modified adipose-derived mesenchymal stem cells protect Parkinson’s disease	93
M2 Macrophage-Derived Exosomal lncRNA AFAP1-AS1 and MicroRNA-26a Affect Cell Migration and Metastasis in Esophageal Cancer	92
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis	91
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration	91
Circular RNA: an important player with multiple facets to regulate its parental gene expression	89
Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling	77
Oncogenic Role of Long Noncoding RNAMALAT1 in Thyroid Cancer Progression through Regulation of the miR-204/IGF2BP2/m6A-MYC Signaling	72
Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway	71
m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression	67
Artificial intelligence for drug discovery: Resources, methods, and applications	66
Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer	66
Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression	64
MSC-Derived Exosomes Protect Vertebral Endplate Chondrocytes against Apoptosis and Calcification via the miR-31-5p/ATF6 Axis	64
ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss	62
DeepACP: A Novel Computational Approach for Accurate Identification of Anticancer Peptides by Deep Learning Algorithm	60
The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases	60
A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-2	59

miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review	58
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and transcriptional activities of ECs in CC	57
LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics	57
lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment	57
hsa_circ_0001955 Enhances In Vitro Proliferation, Migration, and Invasion of HCC Cells through miR-145-5p/NRAS Axis	57
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3	56
Epigenetics: Roles and therapeutic implications of non-coding RNA modifications in human cancers	56
Cell death pathways and viruses: Role of microRNAs	56
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein	55
RETRACTED: YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner	55
Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia	55
Role of circRNA-miRNA-mRNA interaction network in diabetes and its associated complications	52
Exosome-transmitted miRNA-335-5p promotes colorectal cancer invasion and metastasis by facilitating EMT via targeting RASA1	52
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis	52
The role of M6A modification in the regulation of tumor-related lncRNAs	52
Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer	51
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways	51
Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC	50
Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks	49
RETRACTED: METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung	49
Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC	48
Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes	48
Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance	47
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin	47
Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL	46
Mesenchymal stem-cell-derived exosomal miR-145 inhibits atherosclerosis by targeting JAM-A	46
DdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome	45
Dual inhibition of TMPRSS2 and Cathepsin B prevents SARS-CoV-2 infection in iPS cells	45
ncRNAs-mediated high expression of SEMA3F correlates with poor prognosis and tumor immune infiltration of hepatocellular carcinoma	44
Targeting the epigenome in in-stent restenosis: from mechanisms to therapy	44
Circular RNA circTMEM45A Acts as the Sponge of MicroRNA-665 to Promote Hepatocellular Carcinoma Progression	44
Circular RNA circCUL3 Accelerates the Warburg Effect Progression of Gastric Cancer through Regulating the STAT3/HK2 Axis	44
Microfluidics for detection of exosomes and microRNAs in cancer: State of the art	44
circRNA CDR1as Promotes Pulmonary Artery Smooth Muscle Cell Calcification by Upregulating CAMK2D and CNN3 via Sponging miR-7-5p	44
Regulatory roles of tRNA-derived RNA fragments in human pathophysiology	43
Engineering highly efficient backsplicing and translation of synthetic circRNAs	43
lncRNA SNHG10 Promotes the Proliferation and Invasion of Osteosarcoma via Wnt/β-Catenin Signaling	43
Exosomal Long Non-coding RNAs: Emerging Players in the Tumor Microenvironment	43
Inhibition of Zika virus replication by G-quadruplex-binding ligands	43
Glioma-targeted delivery of exosome-encapsulated antisense oligonucleotides using neural stem cells	42
METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway	42
miR-204 silencing reduces mitochondrial autophagy and ROS production in a murine AD model via the TRPML1-activated STAT3 pathway	42
LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer	41
Efficient suppression of endogenous CFTR nonsense mutations using anticodon-engineered transfer RNAs	41
An immunogenomic signature for molecular classification in hepatocellular carcinoma	40
Empirical Comparison and Analysis of Web-Based DNA N4-Methylcytosine Site Prediction Tools	40
Emerging roles of circRNAs in the pathological process of myocardial infarction	40
Synovial Mesenchymal Stem Cell-Derived EV-Packaged miR-31 Downregulates Histone Demethylase KDM2A to Prevent Knee Osteoarthritis	40
circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression	40
miR-223-3p as a potential biomarker and player for adipose tissue dysfunction preceding type 2 diabetes onset	39

miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer	39
FTO-mediated demethylation of GADD45B promotes myogenesis through the activation of p38 MAPK pathway	38
Biological roles and therapeutic potential of circular RNAs in osteoarthritis	38
The Opposing Effect of Type I IFN on the T Cell Response by Non-modified mRNA-Lipoplex Vaccines Is Determined by the Route of Administration	38
METTL14 Gene Polymorphisms Confer Neuroblastoma Susceptibility: An Eight-Center Case-Control Study	38
circRNA circARNT2 Suppressed the Sensitivity of Hepatocellular Carcinoma Cells to Cisplatin by Targeting the miR-155-5p/PDK1 Axis	38
SMC1A regulated by KIAA1429 in m6A-independent manner promotes EMT progress in breast cancer	37
circGNAQ, a circular RNA enriched in vascular endothelium, inhibits endothelial cell senescence and atherosclerosis progression	36
Notochordal-Cell-Derived Exosomes Induced by Compressive Load Inhibit Angiogenesis via the miR-140-5p/Wnt/β-Catenin Axis	36
Long noncoding RNA Cfast regulates cardiac fibrosis	36
miR-150-Based RNA Interference Attenuates Tubulointerstitial Fibrosis through the SOCS1/JAK/STAT Pathway In Vivo and In Vitro	36
The RNA-Binding Protein CELF2 Inhibits Ovarian Cancer Progression by Stabilizing FAM198B	36
Exosomal microRNAs synergistically trigger stromal fibroblasts in breast cancer	36
miR-144 delivered by nasopharyngeal carcinoma-derived EVs stimulates angiogenesis through the FBXW7/HIF-1α/VEGF-A axis	35
CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells	35
Rationale and strategies for the development of safe and effective optimized AAV vectors for human gene therapy	35
METTL14-mediated Lnc-LSG1 m6A modification inhibits clear cell renal cell carcinoma metastasis via regulating ESRP2 ubiquitination	35
Placental trophoblast cell-derived exosomal microRNA-1290 promotes the interaction between endometrium and embryo by targeting LHX6	35
Circular RNA: A potential diagnostic, prognostic, and therapeutic biomarker for human triple-negative breast cancer	35
Comprehensive analysis to identify DLEU2L/TAOK1 axis as a prognostic biomarker in hepatocellular carcinoma	35
The Circular RNA-miRNA Axis: A Special RNA Signature Regulatory Transcriptome as a Potential Biomarker for OSCC	35
Therapeutic potential and recent advances on targeting mitochondrial dynamics in cardiac hypertrophy: A concise review	34
lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep	34
HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing	34
miR-23b-3p rescues cognition in Alzheimer’s disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways	34
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer’s disease	34
Biological Implications and Clinical Potential of Metastasis-Related miRNA in Colorectal Cancer	34
Predicting transcription factor binding sites using DNA shape features based on shared hybrid deep learning architecture	34
Base-modified aptamers obtained by cell-internalization SELEX facilitate cellular uptake of an antisense oligonucleotide	33
Cathepsin B deteriorates diabetic cardiomyopathy induced by streptozotocin via promoting NLRP3-mediated pyroptosis	33
Silencing of lncRNA XIST impairs angiogenesis and exacerbates cerebral vascular injury after ischemic stroke	33
Amido-Bridged Nucleic Acid-Modified Antisense Oligonucleotides Targeting SYT13 to Treat Peritoneal Metastasis of Gastric Cancer	33
Exosomal LINC00174 derived from vascular endothelial cells attenuates myocardial I/R injury via p53-mediated autophagy and apoptosis	33
Upregulation of long non-coding RNA SNHG16 promotes diabetes-related RMEC dysfunction via activating NF-κB and PI3K/AKT pathways	32
ZEB1-Mediated Transcriptional Upregulation of circWWC3 Promotes Breast Cancer Progression through Activating Ras Signaling Pathway	32
5′-tiRNA-Cys-GCA regulates VSMC proliferation and phenotypic transition by targeting STAT4 in aortic dissection	32
Comprehensive analysis of N6-methylandenosine regulators and m6A-related RNAs as prognosis factors in colorectal cancer	32
Hypoxic ucMSC-secreted exosomal miR-125b promotes endothelial cell survival and migration during wound healing by targeting TP53INP1	32
Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation	32
Development of an mRNA replacement therapy for phenylketonuria	32
TAM-derived extracellular vesicles containing microRNA-29a-3p explain the deterioration of ovarian cancer	32
TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway	31
First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers	31
Double-stranded RNA reduction by chaotropic agents during in vitro transcription of messenger RNA	31
LINC-PINT Suppresses the Aggressiveness of Thyroid Cancer by Downregulating miR-767-5p to Induce TET2 Expression	31
circFOXM1 contributes to sorafenib resistance of hepatocellular carcinoma cells by regulating MECP2 via miR-1324	31
LINC00857 Interacting with YBX1 to Regulate Apoptosis and Autophagy via MET and Phosphor-AMPKa Signaling	31
Endometrial cell-derived small extracellular vesicle miR-100-5p promotes functions of trophoblast during embryo implantation	31
Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages	31
circRNA hsa_circ_0018414 inhibits the progression of LUAD by sponging miR-6807-3p and upregulating DKK1	31
miR-146b-5p Enhances the Sensitivity of NSCLC to EGFR Tyrosine Kinase Inhibitors by Regulating the IRAK1/NF-κB Pathway	31
Gene therapy to enhance angiogenesis in chronic wounds	31
Preeclampsia-Associated lncRNA INHBA-AS1 Regulates the Proliferation, Invasion, and Migration of Placental Trophoblast Cells	31
GC-Derived EVs Enriched with MicroRNA-675-3p Contribute to the MAPK/PD-L1-Mediated Tumor Immune Escape by Targeting CXXC4	30
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes	30
Long non-coding RNA linc00665 inhibits CDKN1C expression by binding to EZH2 and affects cisplatin sensitivity of NSCLC cells	30
Recent research progress on circular RNAs: Biogenesis, properties, functions, and therapeutic potential	30
MBD2 Mediates Septic AKI through Activation of PKCη/p38MAPK and the ERK1/2 Axis	29
Smart exosomes with lymph node homing and immune-amplifying capacities for enhanced immunotherapy of metastatic breast cancer	29
circEYA1 Functions as a Sponge of miR-582-3p to Suppress Cervical Adenocarcinoma Tumorigenesis via Upregulating CXCL14	29
D614G mutation eventuates in all VOI and VOC in SARS-CoV-2: Is it part of the positive selection pioneered by Darwin?	29
Combining an optimized mRNA template with a double purification process allows strong expression of in vitro transcribed mRNA	29
miR-21 mimic blocks obesity in mice: A novel therapeutic option	29
NGS-based accurate and efficient detection of circulating cell-free mitochondrial DNA in cancer patients	29
CircHGF suppressed cell proliferation and osteogenic differentiation of BMSCs in ONFH via inhibiting miR-25-3p binding to SMAD7	29
circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression	29
Association of clock-like mutational signature with immune checkpoint inhibitor outcome in patients with melanoma and NSCLC	29
Genomic analysis uncovers prognostic and immunogenic characteristics of ferroptosis for clear cell renal cell carcinoma	29
Müller glia-derived exosomal miR-9-3p promotes angiogenesis by restricting sphingosine-1-phosphate receptor S1P1 in diabetic retinopathy	29
Exosomal Delivery of AntagomiRs Targeting Viral and Cellular MicroRNAs Synergistically Inhibits Cancer Angiogenesis	29
TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination	29
Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis	29
MicroRNA-135a-5p Promotes the Functional Recovery of Spinal Cord Injury by Targeting SP1 and ROCK	29
Gain of Function of Ion Channel TRPV1 Exacerbates Experimental Colitis by Promoting Dendritic Cell Activation	29
circFLT1 and lncCCPG1 Sponges miR-93 to Regulate the Proliferation and Differentiation of Adipocytes by Promoting lncSLC30A9 Expression	28
Intratumoral delivered novel circular mRNA encoding cytokines for immune modulation and cancer therapy	28
Design and lyophilization of lipid nanoparticles for mRNA vaccine and its robust immune response in mice and nonhuman primates	28
Cardiomyocyte mitochondrial dynamic-related lncRNA 1 (CMDL-1) may serve as a potential therapeutic target in doxorubicin cardiotoxicity	28
Osteoclast-derived small extracellular vesicles induce osteogenic differentiation via inhibiting ARHGAP1	28
Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information	28

lncRNA MIR210HG promotes the progression of endometrial cancer by sponging miR-337-3p/137 via the HMGA2-TGF-β/Wnt pathway	28
Non-coding RNA basis of muscle atrophy	28
The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease	28
ncRNA therapy with miRNA-22-3p suppresses the growth of triple-negative breast cancer	28
Regulation of pyroptosis in cardiovascular pathologies: Role of noncoding RNAs	28
Mechanisms of NAT10 as ac4C writer in diseases	28
Neutrophil-like cell membrane-coated siRNA of lncRNA AABR07017145.1 therapy for cardiac hypertrophy via inhibiting ferroptosis of CMECs	28
Autophagy in cardiovascular diseases: role of noncoding RNAs	28
CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs	27
Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis	27
m5UPred: A Web Server for the Prediction of RNA 5-Methyluridine Sites from Sequences	27
miR-181a, delivered by hypoxic PTC-secreted exosomes, inhibits DACT2 by downregulating MLL3, leading to YAP-VEGF-mediated angiogenesis	27
lncRNA GAS6-AS1 inhibits progression and glucose metabolism reprogramming in LUAD via repressing E2F1-mediated transcription of GLUT1	27
Hepatocyte-derived exosomal miR-27a activates hepatic stellate cells through the inhibition of PINK1-mediated mitophagy in MAFLD	27
Circular RNA circRIMS1 Acts as a Sponge of miR-433-3p to Promote Bladder Cancer Progression by Regulating CCAR1 Expression	27
Exosome-derived noncoding RNAs: Function, mechanism, and application in tumor angiogenesis	27
Long noncoding RNA SMUL suppresses SMURF2 production-mediated muscle atrophy via nonsense-mediated mRNA decay	26
Inhibition of IKKβ/NF-κB signaling facilitates tendinopathy healing by rejuvenating inflamm-aging induced tendon-derived stem/progenitor cell senescence	26
CBX2 and EZH2 cooperatively promote the growth and metastasis of lung adenocarcinoma	26
SPI1-induced downregulation of FTO promotes GBM progression by regulating pri-miR-10a processing in an m6A-dependent manner	26
Effects of long-term culture on the biological characteristics and RNA profiles of human bone-marrow-derived mesenchymal stem cells	26
LINC00941 promotes glycolysis in pancreatic cancer by modulating the Hippo pathway	26
Recent advances in crosstalk between N6-methyladenosine (m6A) modification and circular RNAs in cancer	25
mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD	25
STAT3-Induced lncRNA SNHG17 Exerts Oncogenic Effects on Ovarian Cancer through Regulating CDK6	25
Internal m7G methylation: A novel epitranscriptomic contributor in brain development and diseases	25
DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer	25
Novel insights into the interaction between N6-methyladenosine modification and circular RNA	25
Age-associated changes in microglia and astrocytes ameliorate blood-brain barrier dysfunction	25
Chemical optimization of siRNA for safe and efficient silencing of placental sFLT1	25
Naringin improves sepsis-induced intestinal injury by modulating macrophage polarization via PPARγ/miR-21 axis	25
A more efficient CRISPR-Cas12a variant derived from Lachnospiraceae bacterium MA2020	24
lncRNA HotairM1 Depletion Promotes Self-Renewal of Cancer Stem Cells through HOXA1-Nanog Regulation Loop	24
Transfer of microRNA-25 by colorectal cancer cell-derived extracellular vesicles facilitates colorectal cancer development and metastasis	24
Lipid nanoparticle delivery of unmodified mRNAs encoding multiple monoclonal antibodies targeting poxviruses in rabbits	24
ROS/NF-κB Signaling Pathway-Mediated Transcriptional Activation of TRIM37 Promotes HBV-Associated Hepatic Fibrosis	24
LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/αvβ3 integrin/FAK-MAPK axis in ICC	24
RETRACTED: miR-146a inhibits mitochondrial dysfunction and myocardial infarction by targeting cyclophilin D	24
hsa_circNFXL1_009 modulates apoptosis, proliferation, migration, and potassium channel activation in pulmonary hypertension	24
Cancer immunomodulation using bispecific aptamers	24
Precise detection of CRISPR-Cas9 editing in hair cells in the treatment of autosomal dominant hearing loss	24
Aberrant elevation of GDF8 impairs granulosa cell glucose metabolism via upregulating SERPINE1 expression in patients with PCOS	24
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy	24
lncRNA PRR34-AS1 promotes HCC development via modulating Wnt/β-catenin pathway by absorbing miR-296-5p and upregulating E2F2 and SOX12	24
The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by binding polyadenylate-binding protein 2 to stabilize SREBP1 mRNA	24
Genetic or siRNA inhibition of MBD2 attenuates the UUO- and I/R-induced renal fibrosis via downregulation of EGR1	24
Circular RNAs in prostate cancer: Biogenesis, biological functions, and clinical significance	23
Tumor suppressor lnc-CTSLP4 inhibits EMT and metastasis of gastric cancer by attenuating HNRNPAB-dependent Snail transcription	23
miR-301a-PTEN-AKT Signaling Induces Cardiomyocyte Proliferation and Promotes Cardiac Repair Post-MI	23
circNR3C1 Suppresses Bladder Cancer Progression through Acting as an Endogenous Blocker of BRD4/C-myc Complex	23
MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660	23
Super-enhancer-driven lncRNA-DAW promotes liver cancer cell proliferation through activation of Wnt/β-catenin pathway	23
Preclinical evaluation of WVE-004, an investigational stereopure oligonucleotide for the treatment of C9orf72-associated ALS or FTD	23
Improved cardiac-specific delivery of RAGE siRNA within small extracellular vesicles engineered to express intense cardiac targeting peptide attenuates myocarditis	23
miR-27a-3p Targets ATF3 to Reduce Calcium Deposition in Vascular Smooth Muscle Cells	23
ATF2-Induced lncRNA GAS8-AS1 Promotes Autophagy of Thyroid Cancer Cells by Targeting the miR-187-3p/ATG5 and miR-1343-3p/ATG7 Axes	23
KLF5-Modulated lncRNA NEAT1 Contributes to Tumorigenesis by Acting as a Scaffold for BRG1 to Silence GADD45A in Gastric Cancer	23
Long non-coding RNA lnc-CCNL1-3:1 promotes granulosa cell apoptosis and suppresses glucose uptake in women with polycystic ovary syndrome	23
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders	22
RETRACTED: Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma	22
Circular RNA in tumor metastasis	22
Rise of TRIM8: A Molecule of Duality	22
Cytidine-containing tails robustly enhance and prolong protein production of synthetic mRNA in cell and in vivo	22
LINC01094 promotes pancreatic cancer progression by sponging miR-577 to regulate LIN28B expression and the PI3K/AKT pathway	22
circ_2858 Helps Blood-Brain Barrier Disruption by Increasing VEGFA via Sponging miR-93-5p during Escherichia coli Meningitis	22
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering	22
Cas-CLOVER is a novel high-fidelity nuclease for safe and robust generation of TSCM-enriched allogeneic CAR-T cells	22
Hepatocellular carcinoma progression mediated by hepatitis B virus-encoded circRNA HBV_circ_1 through interaction with CDK1	22
CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling	22
Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer	22
HnRNP-L-regulated circCSPP1/miR-520h/EGR1 axis modulates autophagy and promotes progression in prostate cancer	22
miR-940 is a new biomarker with tumor diagnostic and prognostic value	22
lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1	22
Yeast microcapsule-mediated oral delivery of IL-1β shRNA for post-traumatic osteoarthritis therapy	22
MALAT1 sponges miR-26a and miR-26b to regulate endothelial cell angiogenesis via PFKFB3-driven glycolysis in early-onset preeclampsia	22
The role of non-coding RNAs in chemotherapy for gastrointestinal cancers	22
MicroRNA-22 Inhibits the Apoptosis of Vascular Smooth Muscle Cell by Targeting p38MAPKα in Vascular Remodeling of Aortic Dissection	22
Emerging roles of circular RNAs in systemic lupus erythematosus	21
The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy	21
CircRNA Chordc1 protects mice from abdominal aortic aneurysm by contributing to the phenotype and growth of vascular smooth muscle cells	21
Heterogeneity of human corneal endothelium implicates lncRNA NEAT1 in Fuchs endothelial corneal dystrophy	21
Dual effects of N6-methyladenosine on cancer progression and immunotherapy	21
Serum lncRNAs in early pregnancy as potential biomarkers for the prediction of pregnancy-induced hypertension, including preeclampsia	21
The circular RNA circNlgnmediates doxorubicin-inducedcardiac remodeling and fibrosis	21
A cell-penetrating peptide enhances delivery and efficacy of phosphorodiamidate morpholino oligomers in mdx mice	21
lncRNA RP11-624L4.1 Is Associated with Unfavorable Prognosis and Promotes Proliferation via the CDK4/6-Cyclin D1-Rb-E2F1 Pathway in NPC	21
A tRNA-derived fragment from Chinese yew suppresses ovarian cancer growth via targeting TRPA1	21
Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs	21
RETRACTED: MTTL3 upregulates microRNA-1246 to promote occurrence and progression of NSCLC via targeting paternally expressed gene 3	21
MicroRNA-3613-5p Promotes Lung Adenocarcinoma Cell Proliferation through a RELA and AKT/MAPK Positive Feedback Loop	21
Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations	21
RETRACTED: m6A demethylase FTO suppresses pancreatic cancer tumorigenesis by demethylating PJA2 and inhibiting Wnt signaling	21
Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b	21
ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment	21
Essential role of ALKBH5-mediated RNA demethylation modification in bile acid-induced gastric intestinal metaplasia	20