OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Therapy-Nucleic Acids is 47. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Characterization of the Immune Cell Infiltration Landscape in Head and Neck Squamous Cell Carcinoma to Aid Immunotherapy	185
Immune-Related lncRNA to Construct Novel Signature and Predict the Immune Landscape of Human Hepatocellular Carcinoma	151
m6A-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with LUAD	145
Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer	118
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis	114
An Interpretable Prediction Model for Identifying N7-Methylguanosine Sites Based on XGBoost and SHAP	109
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury	101
circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression	99
Exosomes derived from miR-188-3p-modified adipose-derived mesenchymal stem cells protect Parkinson’s disease	93
M2 Macrophage-Derived Exosomal lncRNA AFAP1-AS1 and MicroRNA-26a Affect Cell Migration and Metastasis in Esophageal Cancer	92
lncRNA-Xist/miR-101-3p/KLF6/C/EBPα axis promotes TAM polarization to regulate cancer cell proliferation and migration	91
Exosome-Shuttled circSHOC2 from IPASs Regulates Neuronal Autophagy and Ameliorates Ischemic Brain Injury via the miR-7670-3p/SIRT1 Axis	91
Circular RNA: an important player with multiple facets to regulate its parental gene expression	89
Overexpression of circRNA circUCK2 Attenuates Cell Apoptosis in Cerebral Ischemia-Reperfusion Injury via miR-125b-5p/GDF11 Signaling	77
Oncogenic Role of Long Noncoding RNAMALAT1 in Thyroid Cancer Progression through Regulation of the miR-204/IGF2BP2/m6A-MYC Signaling	72
Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway	71
m6A modification of circHPS5 and hepatocellular carcinoma progression through HMGA2 expression	67
Artificial intelligence for drug discovery: Resources, methods, and applications	66
Exosomal miR-590-3p derived from cancer-associated fibroblasts confers radioresistance in colorectal cancer	66
MSC-Derived Exosomes Protect Vertebral Endplate Chondrocytes against Apoptosis and Calcification via the miR-31-5p/ATF6 Axis	64
Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression	64
ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone loss	62
The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases	60
DeepACP: A Novel Computational Approach for Accurate Identification of Anticancer Peptides by Deep Learning Algorithm	60
A novel G-quadruplex aptamer-based spike trimeric antigen test for the detection of SARS-CoV-2	59

miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review	58
LncRNAs associated with glioblastoma: From transcriptional noise to novel regulators with a promising role in therapeutics	57
lncRNA and breast cancer: Progress from identifying mechanisms to challenges and opportunities of clinical treatment	57
hsa_circ_0001955 Enhances In Vitro Proliferation, Migration, and Invasion of HCC Cells through miR-145-5p/NRAS Axis	57
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and transcriptional activities of ECs in CC	57
Epigenetics: Roles and therapeutic implications of non-coding RNA modifications in human cancers	56
Cell death pathways and viruses: Role of microRNAs	56
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3	56
RETRACTED: YTHDF1 Facilitates the Progression of Hepatocellular Carcinoma by Promoting FZD5 mRNA Translation in an m6A-Dependent Manner	55
Cancer-derived exosome miRNAs induce skeletal muscle wasting by Bcl-2-mediated apoptosis in colon cancer cachexia	55
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein	55
Exosome-transmitted miRNA-335-5p promotes colorectal cancer invasion and metastasis by facilitating EMT via targeting RASA1	52
Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis	52
The role of M6A modification in the regulation of tumor-related lncRNAs	52
Role of circRNA-miRNA-mRNA interaction network in diabetes and its associated complications	52
Biogenesis, functions, and clinical implications of circular RNAs in non-small cell lung cancer	51
miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways	51
Pyroptosis-related lncRNAs are potential biomarkers for predicting prognoses and immune responses in patients with UCEC	50
Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks	49
RETRACTED: METTL3-mediated m6A modification of ZBTB4 mRNA is involved in the smoking-induced EMT in cancer of the lung	49
Comprehensive landscape of epigenetic-dysregulated lncRNAs reveals a profound role of enhancers in carcinogenesis in BC subtypes	48
Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC	48
Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin	47
Advances in mRNA 5-methylcytosine modifications: Detection, effectors, biological functions, and clinical relevance	47