OOIR: Observatory of International Research

Papers

(The median citation count of Advances in Wound Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Diagnostic Performance of Ultrasonography for Diabetic Foot Osteomyelitis	312
Development of a Tissue Oxygenation Flow-Based Index Toward Discerning the Healing Status in Diabetic Foot Ulcers	158
Dynamic Prediction of Time to Wound Healing at Routine Wound Care Visits	145
Efficacy of D33 Sealed Foam in Preventing Skin Injury from Surgical Positioning: Randomized Clinical Trial	122
Frailty Predicts Postoperative Complications in Patients Undergoing Surgery for Diabetic Foot Ulcers	87
Efficacy and Safety of Lidocaine Patch in the Management of Acute Postoperative Wound Pain: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials	81
Efficacy and Safety of Human Amniotic Membrane for Chronic Wounds: A Systematic Review and Meta-Analysis of Clinical Trials	70
Vasoconstrictor Agent Administration as a Risk Factor for Pressure Injury Development in Intensive Care Unit Patients: A Systematic Review and Meta-Analysis	70
Individualized Risk Prediction for Improved Chronic Wound Management	65
Pressure Injury Incidence and Quality of Care Index (1990–2021): An Analysis of Trends and Health Inequalities Based on the Study of Global Burden of Disease 2021	60
Standardized Wound Care: Patchwork Practices?	60
From Chronic Wounds to Scarring: The Growing Health Care Burden of Under- and Over-Healing Wounds	59
Electrically Conductive Hydrogels for Wound Healing	58
Patterns of Co-Occurring Pressure Injuries: A Data-Driven Study Using Real-World Clinical Records	58
Prevalent Types of Peristomal Skin Damage During Chemoradiotherapy and Their Risk Factors	57
Advancing Therapeutic Solutions for Burn Wounds: Potential Use of Noninvasive Ultrasound-Driven Splenic Stimulation	56
Effects of ON101 for Hard-to-Heal Diabetic Foot Ulcers in a Randomized Phase III Trial: A Post Hoc Analysis	50
Counting the Cost of Cellular and/or Tissue-Based Products in Diabetic Foot Ulcers: Is There a Justifiable Price Limit per Square Centimeter?	47
In Sequence Antifibrotic Treatment and Rehabilitation after Volumetric Muscle Loss Injury	46
Extrusion-Based 3D Bioprinting of Bioactive and Piezoelectric Scaffolds as Potential Therapy for Treating Critical Soft Tissue Wounds	41
Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation	39
Integration of Flow Cytometry and Single-Cell RNA Sequencing Analysis to Explore the Fibroblast Subpopulations in Keloid that Correlate with Recurrence	36
Incisional Negative Pressure Wound Therapy Versus Primary Wound Suturing after Intestinal Ostomy Closure: A Systematic Review and Meta-Analysis	33
Image-Based Artificial Intelligence in Wound Assessment: A Systematic Review	32
Application of Perioperative Real-Time Fluorescence Imaging to Achieve High-Quality Debridement: A Randomized Control Trial	31

Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine	31
An Evidence Map of Clinical Practice Guideline Recommendations and Quality on Venous Leg Ulcer	31
Reliability of an AI-Powered Application Across Different Mobile Devices for Assessment of Chronic Wounds	30
Global Burden of Pressure Ulcer and Contributing Factors from 1990 to 2021: A Systematic Analysis with Forecasts to 2035	29
Structured Exercise Therapy Increases Endogenous Antioxidants to Repair Muscle Strength and Health in Porcine Ischemic Myopathy Model of Peripheral Artery Disease	28
Prophylactic Negative Pressure Wound Therapy in Reducing Surgical Site Infections in Closed Abdominal Incision: A Randomized Controlled Trial	28
Multifunctional Elastin-Like Polypeptide Fusion Protein Coacervates Inhibit Receptor-Mediated Proinflammatory Signals and Promote Angiogenesis in Mouse Diabetic Wounds	28
The Promising Hydrogel Candidates for Preclinically Treating Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis	27
Prediction Models for Intraoperative Acquired Pressure Injury of Adults: A Systematic Review and Critical Appraisal	26
Moisturizers, Emollients, or Barrier Preparations for the Prevention of Pressure Injury: A Systematic Review and Meta-Analysis	23
The Unique Roles of Adipose Tissue in Wound Healing	22
Prognostic Nutritional Index as a Predictor of Mortality in Intensive Care Unit Patients with Pressure Injuries: Insights from a Large Cohort Study	22
Innovations in Stem Cell Therapy for Diabetic Wound Healing	22
In Vivo , Label-Free Multiphoton Microscopy Is Sensitive to Altered Metabolism and Structure in Aged Skin	22
Management of Diabetic Wounds: Expert Panel Consensus Statement	21
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial	21
Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing	20
Split-Thickness Skin and Dermal Pixel Grafts Can Be Expanded up to 500 Times to Re-Epithelialize a Full-Thickness Burn Wound	20
The Association Between Risk-Adjusted Wound Healing Rates and Long-Term Outcomes in a Network of U.S. Wound Care Clinics	20
How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs	20
Understanding Scarring in the Oral Mucosa	19
Diabetic Wound Vasculopathy and Neuropathy: Spotlight on Wound Lipid Signaling	17
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat Accelerates Wound Healing in a Mouse Hind limb Lymphedema Model	17
Acknowledgment of Reviewers 2022	16
Correction to: Reduced Hospitalizations and Amputations in Patients with Diabetic Foot Ulcers Treated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outc	16
Novel Topical Esmolol Hydrochloride (Galnobax) for Diabetic Foot Wound: Phase 1/2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Parallel-Group Study	15
Pulse Capacitive Coupling Electric Field Regulates Cell Migration, Proliferation, Polarization, and Vascularization to Accelerate Wound Healing	15
Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers	15
Inflammation in Wound Healing and Pathological Scarring	13
Smoking Status Impacts Mitochondrial Function and Synthetic Function in Mesenchymal Stem Cells Derived from Diabetics with Arterial Insufficiency	13
Lineage Mapping of Extracellular Vesicles: What Cells Do They Come from and Where Do They Go?	13
Human Amniotic Membrane Promotes Angiogenesis in an Oxidative Stress Chronic Diabetic Murine Wound Model	13
Protein-Based Nutrition for Chronic Wounds: A Clinician’s Guide to Patient Selection, Dosing, Monitoring, and Outcomes	13
Trends and Innovation in Negative Pressure Wound Therapy: A Review of Burn Wound Management	13
The Pathophysiology and Management of Pathologic Scarring—a Contemporary Review	12
The Science of Skin: Measuring Damage and Assessing Risk	12
Getting Started on Artificial Intelligence in Health Care and Clinical Research: Includes Rigor Checklist for Authors and Reviewers	12
The Correlation Between Wound Bed Preparation and Wound Closure in Venous Leg Ulcers: A Post Hoc Analysis of the ChronEx Multicenter Randomized Controlle	11
Efficacy of a Novel Daily-Use Hydrocolloid Pad on Wound Healing: Findings of a 16-Day, Single-Center, Randomized, Controlled Study	11
Skin Inflammation with a Focus on Wound Healing	11
Chemotherapy-Mediated Complications of Wound Healing: An Understudied Side Effect	11
The Invisible Wound: Silent Focal Breach of Skin Integrity that Cascades into Systemic Dysfunction and Chronic Morbidity	11
Nitrous Oxide to Reduce Wound Care–Related Pain in Adults: A Systematic Review and Meta-Analysis	11
Clinical Features and Mechanisms of Differential Wound Healing and Scarring Across Anatomical Sites	11
Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature	11
Tissue Engineering-Based Strategies for Diabetic Foot Ulcer Management	10
The Shizuoka Study of a Population-Based Retrospective Cohort for the Evaluation of Risk of Pressure Injury in the Elderly	10
Acknowledgment of Reviewers 2023	10
The Challenge of Healing Wounds in Radiation-Injured Skin	10
Debridement of Diabetic Foot Ulcers	10

Cerium Nitrate Stiffens In Vitro Skin Models and Reduces Pseudomonas aeruginosa Pathogenicity and Penetrat	10
Artificial Skin Therapies; Strategy for Product Development	9
Biosponge-Encased Placental Stem Cells for Volumetric Muscle Loss Repair	9
Immune Imbalance Drives Keloid Pathogenesis: Emerging Targets for Precision Immunotherapy	9
Nanosheet Promotes Chronic Wound Healing by Localizing Uncultured Stromal Vascular Fraction Cells	9
Adult Burn Survivors Face Elevated Long-Term Risk of Major Adverse Cardiovascular Events, Venous Thromboembolism, and Mortality: A Real-World Analysis	9
Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial	9
The WOUND-Q Function and Symptoms Scales for Chronic Lower Extremity Wounds: A Validation Study	9
Re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions” by Bull et al.	9
Dual-Action Topical Therapy Accelerates Healing of MRSA-Infected Burn Wounds by Targeting Infection and Inflammation	8
Alpha-1-Antitrypsin Enhances Fat Graft Survival in a Murine Model	8
Current Methodologies for Inducing Aligned Myofibers in Tissue Constructs for Skeletal Muscle Tissue Regeneration	8
New Opportunities for Electric Fields in Promoting Wound Healing: Collective Electrotaxis	8
A First-in-Human Randomized Clinical Study Investigating the Safety and Tolerability of Stabilized Hypochlorous Acid in Patients with Chronic Leg Ulcers	8
The Effect of Telemedicine Interventions on Patients with Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	8
Topical Reconstituted High-Density Lipoproteins Elicit Anti-Inflammatory Effects in Diabetic Wounds	8
Targeting Anaerobic Respiration in Pseudomonas aeruginosa with Chlorate Improves Healing of Chronic Wounds	7
Recent Advances in Functional Wound Dressings	7
Plasma Medicine in Wound Care	7
The Relationship Between Autoimmune Disease and Disease-Modifying Antirheumatic Drugs on Wound Healing	7
Testosterone Promotes Nerve Tethering and Acellular Biomaterial Perineural Fibrosis in a Rat Wound Repair Model	7
Switching from Galenic to Advanced Dressings or Vacuum Assisted Closure Therapy Can Improve Quality of Life of Patients with Chronic Non-Responsive Pressure Skin Ulcers: Preliminary Data with Italian	7
Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations	7
Bridging the Gap: Contemporary Paradigms in Nerve Scaffolds and Regeneration	7
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions	6
Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing	6
Selective Autophagy: A Potential Player in Cutaneous Wound Healing	6
Clinical Measurement of Transepidermal Water Loss	6
The Functionality of High-Density Lipoproteins Is Impaired in People with Diabetes Who Require Minor Amputations	6
The Effectiveness of 595-nm Pulsed Dye Laser for the Treatment of Bilateral Cleft-Lip Scars in Asian Patients: A 6-Month Prospective, Randomized, Self-Controlled Trial	6
Use of Therapeutic RNAs to Accelerate Wound Healing in Diabetic Rabbit Wounds	6
The Role of Hydrogel Biomaterials in the Intervention of Wound Healing and Skin Regeneration via Exosomes: A Systematic Review and Meta-Analysis of Preclinical Animal Studies	6
Gelatin Microspheres Loaded with Wharton's Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice	6
Adipose-Based Therapeutics and Transplantation of Hypodermis	6
Magnetic Resonance Imaging Techniques in Peripheral Arterial Disease	5
Treatment of Surgical Scars with Fractional Carbon Dioxide (CO ₂ ) Laser: A Randomized Controlled Trial	5
Integrating Regenerative Therapies and Artificial Intelligence for Precision Management of Diabetic Foot Ulcers	5
High Transepidermal Water Loss at the Closed Wound Site Marks Compromised Functional Wound Closure and Associates with Wound Recurrence in Diabetic Foot Ulcers: A Prognostic Factor Study	5
Chondrocyte Mitochondrial Quality Control: A Novel Insight into Osteoarthritis and Cartilage Regeneration	5
Deferoxamine to Minimize Fibrosis During Radiation Therapy	5
Acellular Scaffolds for Muscle Regeneration: Advances and Challenges	5
A Novel Xenograft Model Demonstrates Human Fibroblast Behavior During Skin Wound Repair and Fibrosis	5
In Vitro , Ex Vivo , and In Vivo Approaches for Investigation of Skin Scarring:	5
AI-Powered Image-Based Assessment of Pressure Injuries Using You Only Look Once Version 8 (YOLOv8) Models	5
Management of Infected Wounds: A Wound Healing Foundation Consensus Statement	5
Does Warmed Saline Irrigation Improve Comfort During Dressing Changes After Digit Replantation? A Randomized Controlled Trial	5
Prediction of Healing Trajectory of Chronic Wounds Using a Machine Learning Approach	5
Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives	4
Antimicrobial Peptides for Diabetic Wound Healing: Preclinical and Clinical Studies	4
Response to Astrada et al. re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions”	4
Temporal In Vitro Models of Skin Wound Healing Components: A Cell-Specific Framework for Acute and Chronic Repair Mechanisms	4
The Diabetic Foot Consortium Biomarker Platform Study: A New Approach to Advance Diabetic Foot Ulcer Healing	4
Re: “How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs” by Gefen et al.	4
Behind the Scenes of Extracellular Vesicle Therapy for Skin Injuries and Disorders	4
Assessment of Patient-Reported Outcomes for Closed-Incision Negative Pressure Therapy with Wide-Coverage Dressings in Simple Mastectomy and Immediate Implant-Based Breast Reconstruction	4
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound	4
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the “HMGB1-TLR4-Wnt/Notch” Axis	4
Alginate Formulation for Wound Healing Applications	4
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair	4
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Advances in Wound Care	4
Modulation of Lymphangiogenesis in Incisional Murine Diabetic Wound Healing Using Negative Pressure Wound Therapy	4
Comparison of “Semiocclusive Dressing” Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage III/IV Pressure Injuries in the Inflammatory	4
Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response	4