OOIR: Observatory of International Research

Papers

(The median citation count of Advances in Wound Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Individualized Risk Prediction for Improved Chronic Wound Management	402
Pressure Injury Incidence and Quality of Care Index (1990–2021): An Analysis of Trends and Health Inequalities Based on the Study of Global Burden of Disease 2021	181
Development of a Tissue Oxygenation Flow-Based Index Toward Discerning the Healing Status in Diabetic Foot Ulcers	119
Efficacy of D33 Sealed Foam in Preventing Skin Injury from Surgical Positioning: Randomized Clinical Trial	114
Dynamic Prediction of Time to Wound Healing at Routine Wound Care Visits	89
Efficacy and Safety of Lidocaine Patch in the Management of Acute Postoperative Wound Pain: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials	60
Diagnostic Performance of Ultrasonography for Diabetic Foot Osteomyelitis	54
Standardized Wound Care: Patchwork Practices?	52
Vasoconstrictor Agent Administration as a Risk Factor for Pressure Injury Development in Intensive Care Unit Patients: A Systematic Review and Meta-Analysis	50
From Chronic Wounds to Scarring: The Growing Health Care Burden of Under- and Over-Healing Wounds	49
Acknowledgment of Reviewers 2021	45
Advancing Therapeutic Solutions for Burn Wounds: Potential Use of Noninvasive Ultrasound-Driven Splenic Stimulation	40
Electrically Conductive Hydrogels for Wound Healing	40
Patterns of Co-Occurring Pressure Injuries: A Data-Driven Study Using Real-World Clinical Records	39
Prevalent Types of Peristomal Skin Damage During Chemoradiotherapy and Their Risk Factors	39
Integration of Flow Cytometry and Single-Cell RNA Sequencing Analysis to Explore the Fibroblast Subpopulations in Keloid that Correlate with Recurrence	38
Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation	37
Incisional Negative Pressure Wound Therapy Versus Primary Wound Suturing after Intestinal Ostomy Closure: A Systematic Review and Meta-Analysis	36
Counting the Cost of Cellular and/or Tissue-Based Products in Diabetic Foot Ulcers: Is There a Justifiable Price Limit per Square Centimeter?	35
In Sequence Antifibrotic Treatment and Rehabilitation after Volumetric Muscle Loss Injury	33
Effects of ON101 for Hard-to-Heal Diabetic Foot Ulcers in a Randomized Phase III Trial: A Post Hoc Analysis	33
Extrusion-Based 3D Bioprinting of Bioactive and Piezoelectric Scaffolds as Potential Therapy for Treating Critical Soft Tissue Wounds	32
An Evidence Map of Clinical Practice Guideline Recommendations and Quality on Venous Leg Ulcer	31
Image-Based Artificial Intelligence in Wound Assessment: A Systematic Review	31
Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine	30

Genetics and Epigenetics of Keloids	29
Reliability of an AI-Powered Application Across Different Mobile Devices for Assessment of Chronic Wounds	28
Global Burden of Pressure Ulcer and Contributing Factors from 1990 to 2021: A Systematic Analysis with Forecasts to 2035	26
The Promising Hydrogel Candidates for Preclinically Treating Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis	26
Structured Exercise Therapy Increases Endogenous Antioxidants to Repair Muscle Strength and Health in Porcine Ischemic Myopathy Model of Peripheral Artery Disease	25
Multifunctional Elastin-Like Polypeptide Fusion Protein Coacervates Inhibit Receptor-Mediated Proinflammatory Signals and Promote Angiogenesis in Mouse Diabetic Wounds	25
Prophylactic Negative Pressure Wound Therapy in Reducing Surgical Site Infections in Closed Abdominal Incision: A Randomized Controlled Trial	25
Prediction Models for Intraoperative Acquired Pressure Injury of Adults: A Systematic Review and Critical Appraisal	24
Current Overview of Obesity-Induced Lymphedema	23
Moisturizers, Emollients, or Barrier Preparations for the Prevention of Pressure Injury: A Systematic Review and Meta-Analysis	23
Prognostic Nutritional Index as a Predictor of Mortality in Intensive Care Unit Patients with Pressure Injuries: Insights from a Large Cohort Study	22
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial	22
The Unique Roles of Adipose Tissue in Wound Healing	22
Innovations in Stem Cell Therapy for Diabetic Wound Healing	22
Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing	21
Understanding Scarring in the Oral Mucosa	20
The Association Between Risk-Adjusted Wound Healing Rates and Long-Term Outcomes in a Network of U.S. Wound Care Clinics	20
Split-Thickness Skin and Dermal Pixel Grafts Can Be Expanded up to 500 Times to Re-Epithelialize a Full-Thickness Burn Wound	20
Pulse Capacitive Coupling Electric Field Regulates Cell Migration, Proliferation, Polarization, and Vascularization to Accelerate Wound Healing	19
How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs	19
Acknowledgment of Reviewers 2022	19
Correction to: Reduced Hospitalizations and Amputations in Patients with Diabetic Foot Ulcers Treated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outcomes, by Izhakoff Ye	19
Trends and Innovation in Negative Pressure Wound Therapy: A Review of Burn Wound Management	18
Novel Topical Esmolol Hydrochloride (Galnobax) for Diabetic Foot Wound: Phase 1/2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Parallel-Group Study	17
Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers	17
Human Amniotic Membrane Promotes Angiogenesis in an Oxidative Stress Chronic Diabetic Murine Wound Model	17
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat Accelerates Wound Healing in a Mouse Hind limb Lymphedema Model	17
The Science of Skin: Measuring Damage and Assessing Risk	16
The Pathophysiology and Management of Pathologic Scarring—a Contemporary Review	16
Early Intensified Rehabilitation Training with Hyperbaric Oxygen Therapy Improves Functional Disorders and Prognosis of Patients with Traumatic Brain Injury	16
Smoking Status Impacts Mitochondrial Function and Synthetic Function in Mesenchymal Stem Cells Derived from Diabetics with Arterial Insufficiency	16
Lineage Mapping of Extracellular Vesicles: What Cells Do They Come from and Where Do They Go?	16
Inflammation in Wound Healing and Pathological Scarring	15
Getting Started on Artificial Intelligence in Health Care and Clinical Research: Includes Rigor Checklist for Authors and Reviewers	15
Nitrous Oxide to Reduce Wound Care–Related Pain in Adults: A Systematic Review and Meta-Analysis	14
Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature	14
Skin Inflammation with a Focus on Wound Healing	13
Chemotherapy-Mediated Complications of Wound Healing: An Understudied Side Effect	13
Clinical Features and Mechanisms of Differential Wound Healing and Scarring Across Anatomical Sites	13
The Shizuoka Study of a Population-Based Retrospective Cohort for the Evaluation of Risk of Pressure Injury in the Elderly	12
Tissue Engineering-Based Strategies for Diabetic Foot Ulcer Management	12
Debridement of Diabetic Foot Ulcers	11
The WOUND-Q Function and Symptoms Scales for Chronic Lower Extremity Wounds: A Validation Study	11
The Challenge of Healing Wounds in Radiation-Injured Skin	11
Acknowledgment of Reviewers 2023	11
Cerium Nitrate Stiffens In Vitro Skin Models and Reduces Pseudomonas aeruginosa Pathogenicity and Penetration Through Skin Models	11
Re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions” by Bull et al.	10
The Effect of Telemedicine Interventions on Patients with Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	10
Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial	10
Dermal Fibroblast Heterogeneity and Its Contribution to the Skin Repair and Regeneration	10

Biosponge-Encased Placental Stem Cells for Volumetric Muscle Loss Repair	10
Nanosheet Promotes Chronic Wound Healing by Localizing Uncultured Stromal Vascular Fraction Cells	10
Artificial Skin Therapies; Strategy for Product Development	10
Alpha-1-Antitrypsin Enhances Fat Graft Survival in a Murine Model	9
Topical Reconstituted High-Density Lipoproteins Elicit Anti-Inflammatory Effects in Diabetic Wounds	9
Approaches for Regenerative Healing of Cutaneous Wound with an Emphasis on Strategies Activating the Wnt/β-Catenin Pathway	9
The Relationship Between Autoimmune Disease and Disease-Modifying Antirheumatic Drugs on Wound Healing	9
New Opportunities for Electric Fields in Promoting Wound Healing: Collective Electrotaxis	9
Current Methodologies for Inducing Aligned Myofibers in Tissue Constructs for Skeletal Muscle Tissue Regeneration	8
A First-in-Human Randomized Clinical Study Investigating the Safety and Tolerability of Stabilized Hypochlorous Acid in Patients with Chronic Leg Ulcers	8
Targeting Anaerobic Respiration in Pseudomonas aeruginosa with Chlorate Improves Healing of Chronic Wounds	8
Testosterone Promotes Nerve Tethering and Acellular Biomaterial Perineural Fibrosis in a Rat Wound Repair Model	7
Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations	7
Moist Wound Healing with Commonly Available Dressings	7
Switching from Galenic to Advanced Dressings or Vacuum Assisted Closure Therapy Can Improve Quality of Life of Patients with Chronic Non-Responsive Pressure Skin Ulcers: Preliminary Data with Italian	7
Recent Advances in Functional Wound Dressings	6
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions	6
Bridging the Gap: Contemporary Paradigms in Nerve Scaffolds and Regeneration	6
Chondrocyte Mitochondrial Quality Control: A Novel Insight into Osteoarthritis and Cartilage Regeneration	6
Use of Therapeutic RNAs to Accelerate Wound Healing in Diabetic Rabbit Wounds	6
Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing	6
Gelatin Microspheres Loaded with Wharton's Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice	6
Classification of Distinct Endotypes in Human Skin Scarring: S.C.A.R.—A Novel Perspective on Dermal Fibrosis	6
Reporting of Financial Conflicts of Interest in Studies of Placental Membrane Allografts	6
The Role of Hydrogel Biomaterials in the Intervention of Wound Healing and Skin Regeneration via Exosomes: A Systematic Review and Meta-Analysis of Preclinical Animal Studies	6
Clinical Measurement of Transepidermal Water Loss	6
A Review of Hypertrophic Scar and Keloid Treatment and Prevention in the Pediatric Population: Where Are We Now?	6
Prediction of Healing Trajectory of Chronic Wounds Using a Machine Learning Approach	6
Updates on Excisional Procedures for Lymphedema	5
Strategies to Minimize Surgical Scarring: Translation of Lessons Learned from Bedside to Bench and Back	5
Response to Astrada et al. re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions”	5
Behind the Scenes of Extracellular Vesicle Therapy for Skin Injuries and Disorders	5
In Vitro,Ex Vivo, andIn VivoApproaches for Investigation of Skin Scarring: Human and Animal Models	5
Acellular Scaffolds for Muscle Regeneration: Advances and Challenges	5
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair	5
Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives	5
Deferoxamine to Minimize Fibrosis During Radiation Therapy	5
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Advances in Wound Care	5
Cerium Nitrate Treatment in the Management of Burns	5
Selective Autophagy: A Potential Player in Cutaneous Wound Healing	5
High Transepidermal Water Loss at the Closed Wound Site Marks Compromised Functional Wound Closure and Associates with Wound Recurrence in Diabetic Foot Ulcers: A Prognostic Factor Study	5
Magnetic Resonance Imaging Techniques in Peripheral Arterial Disease	5
A Novel Xenograft Model Demonstrates Human Fibroblast Behavior During Skin Wound Repair and Fibrosis	5
AI-Powered Image-Based Assessment of Pressure Injuries Using You Only Look once (YOLO) Version 8 Models	5
Antimicrobial Peptides for Diabetic Wound Healing: Preclinical and Clinical Studies	5
Modulation of Lymphangiogenesis in Incisional Murine Diabetic Wound Healing Using Negative Pressure Wound Therapy	5
The Effectiveness of 595-nm Pulsed Dye Laser for the Treatment of Bilateral Cleft-Lip Scars in Asian Patients: A 6-Month Prospective, Randomized, Self-Controlled Trial	5
Treatment of Surgical Scars with Fractional Carbon Dioxide (CO₂) Laser: A Randomized Controlled Trial	5
Assessment of Patient-Reported Outcomes for Closed-Incision Negative Pressure Therapy with Wide-Coverage Dressings in Simple Mastectomy and Immediate Implant-Based Breast Reconstruction	4
Alginate Formulation for Wound Healing Applications	4
Current Understanding of Pathological Mechanisms of Lymphedema	4
Re: “How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs” by Gefen et al.	4
Pharmaceutical Prophylaxis of Scarring with Emphasis on Burns: A Review of Preclinical and Clinical Studies	4
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound	4
Comparison of “Semiocclusive Dressing” Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage III/IV Pressure Injuries in the Inflammatory	4
Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response	4
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the “HMGB1-TLR4-Wnt/Notch” Axis	4