OOIR: Observatory of International Research

Papers

(The median citation count of Advances in Wound Care is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Efficacy and Safety of Lidocaine Patch in the Management of Acute Postoperative Wound Pain: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Trials	347
Pressure Injury Incidence and Quality of Care Index (1990–2021): An Analysis of Trends and Health Inequalities Based on the Study of Global Burden of Disease 2021	132
Development of a Tissue Oxygenation Flow-Based Index Toward Discerning the Healing Status in Diabetic Foot Ulcers	101
Diagnostic Performance of Ultrasonography for Diabetic Foot Osteomyelitis	95
Efficacy of D33 Sealed Foam in Preventing Skin Injury from Surgical Positioning: Randomized Clinical Trial	80
Standardized Wound Care: Patchwork Practices?	70
Dynamic Prediction of Time to Wound Healing at Routine Wound Care Visits	51
Vasoconstrictor Agent Administration as a Risk Factor for Pressure Injury Development in Intensive Care Unit Patients: A Systematic Review and Meta-Analysis	45
Individualized Risk Prediction for Improved Chronic Wound Management	45
Acknowledgment of Reviewers 2021	44
From Chronic Wounds to Scarring: The Growing Health Care Burden of Under- and Over-Healing Wounds	44
Patterns of Co-Occurring Pressure Injuries: A Data-Driven Study Using Real-World Clinical Records	42
Advancing Therapeutic Solutions for Burn Wounds: Potential Use of Noninvasive Ultrasound-Driven Splenic Stimulation	40
Prevalent Types of Peristomal Skin Damage During Chemoradiotherapy and Their Risk Factors	40
Integration of Flow Cytometry and Single-Cell RNA Sequencing Analysis to Explore the Fibroblast Subpopulations in Keloid that Correlate with Recurrence	39
Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation	36
In Sequence Antifibrotic Treatment and Rehabilitation after Volumetric Muscle Loss Injury	35
Extrusion-Based 3D Bioprinting of Bioactive and Piezoelectric Scaffolds as Potential Therapy for Treating Critical Soft Tissue Wounds	35
Counting the Cost of Cellular and/or Tissue-Based Products in Diabetic Foot Ulcers: Is There a Justifiable Price Limit per Square Centimeter?	34
Incisional Negative Pressure Wound Therapy Versus Primary Wound Suturing after Intestinal Ostomy Closure: A Systematic Review and Meta-Analysis	33
Effects of ON101 for Hard-to-Heal Diabetic Foot Ulcers in a Randomized Phase III Trial: A Post Hoc Analysis	33
Image-Based Artificial Intelligence in Wound Assessment: A Systematic Review	33
Reliability of an AI-Powered Application Across Different Mobile Devices for Assessment of Chronic Wounds	31
An Evidence Map of Clinical Practice Guideline Recommendations and Quality on Venous Leg Ulcer	31
Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine	30

Multidimensional Pain Characteristics in Older Adults with Chronic Venous Leg Ulcers	29
Structured Exercise Therapy Increases Endogenous Antioxidants to Repair Muscle Strength and Health in Porcine Ischemic Myopathy Model of Peripheral Artery Disease	29
Genetics and Epigenetics of Keloids	29
Prediction Models for Intraoperative Acquired Pressure Injury of Adults: A Systematic Review and Critical Appraisal	27
Global Burden of Pressure Ulcer and Contributing Factors from 1990 to 2021: A Systematic Analysis with Forecasts to 2035	27
Prophylactic Negative Pressure Wound Therapy in Reducing Surgical Site Infections in Closed Abdominal Incision: A Randomized Controlled Trial	26
A Scoping Review of the Methodology Used in Studies of Genetic Influences on the Development of Keloid or Hypertrophic Scarring in Adults and Children After Acute Wounding	25
The Promising Hydrogel Candidates for Preclinically Treating Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis	24
Multifunctional Elastin-Like Polypeptide Fusion Protein Coacervates Inhibit Receptor-Mediated Proinflammatory Signals and Promote Angiogenesis in Mouse Diabetic Wounds	23
Innovations in Stem Cell Therapy for Diabetic Wound Healing	21
Using Three-Dimensional Bioprinting to Generate Realistic Models of Wound Healing	20
Moisturizers, Emollients, or Barrier Preparations for the Prevention of Pressure Injury: A Systematic Review and Meta-Analysis	20
Split-Thickness Skin and Dermal Pixel Grafts Can Be Expanded up to 500 Times to Re-Epithelialize a Full-Thickness Burn Wound	20
Current Overview of Obesity-Induced Lymphedema	20
Noninferiority of Copper Dressings Than Negative Pressure Wound Therapy in Healing Diabetic Wounds: A Randomized Clinical Trial	20
Understanding Scarring in the Oral Mucosa	19
The Association Between Risk-Adjusted Wound Healing Rates and Long-Term Outcomes in a Network of U.S. Wound Care Clinics	19
How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs	18
Correction to: Reduced Hospitalizations and Amputations in Patients with Diabetic Foot Ulcers Treated with Cyclical Pressurized Topical Wound Oxygen Therapy: Real-World Outcomes, by Izhakoff Ye	18
Acknowledgment of Reviewers 2022	18
Trends and Innovation in Negative Pressure Wound Therapy: A Review of Burn Wound Management	18
Human Amniotic Membrane Promotes Angiogenesis in an Oxidative Stress Chronic Diabetic Murine Wound Model	17
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat Accelerates Wound Healing in a Mouse Hind limb Lymphedema Model	17
Pulse Capacitive Coupling Electric Field Regulates Cell Migration, Proliferation, Polarization, and Vascularization to Accelerate Wound Healing	17
Smoking Status Impacts Mitochondrial Function and Synthetic Function in Mesenchymal Stem Cells Derived from Diabetics with Arterial Insufficiency	16
Novel Topical Esmolol Hydrochloride (Galnobax) for Diabetic Foot Wound: Phase 1/2, Multicenter, Randomized, Double-Blind, Vehicle-Controlled Parallel-Group Study	16
Lineage Mapping of Extracellular Vesicles: What Cells Do They Come from and Where Do They Go?	16
Associations Among Wound-Related Factors Including Biofilm, Wound-Related Symptoms and Systemic Inflammation in Older Adults with Chronic Venous Leg Ulcers	16
Chemotherapy-Mediated Complications of Wound Healing: An Understudied Side Effect	15
The Science of Skin: Measuring Damage and Assessing Risk	15
The Pathophysiology and Management of Pathologic Scarring—a Contemporary Review	15
Early Intensified Rehabilitation Training with Hyperbaric Oxygen Therapy Improves Functional Disorders and Prognosis of Patients with Traumatic Brain Injury	15
Nitrous Oxide to Reduce Wound Care–Related Pain in Adults: A Systematic Review and Meta-Analysis	15
Inflammation in Wound Healing and Pathological Scarring	15
Approaches to Modulate the Chronic Wound Environment Using Localized Nucleic Acid Delivery	14
Skin Inflammation with a Focus on Wound Healing	14
Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature	14
Cerium Nitrate Stiffens In Vitro Skin Models and Reduces Pseudomonas aeruginosa Pathogenicity and Penetration Through Skin Models	13
Tissue Engineering-Based Strategies for Diabetic Foot Ulcer Management	13
The Shizuoka Study of a Population-Based Retrospective Cohort for the Evaluation of Risk of Pressure Injury in the Elderly	13
Debridement of Diabetic Foot Ulcers	13
Acknowledgment of Reviewers 2023	12
Biosponge-Encased Placental Stem Cells for Volumetric Muscle Loss Repair	12
Nanosheet Promotes Chronic Wound Healing by Localizing Uncultured Stromal Vascular Fraction Cells	11
The Analgesic Benefits of Ketorolac to Local Anesthetic Wound Infiltration Is Statistically Significant But Clinically Unimportant: A Comprehensive Systematic Review and Meta-Analysis	11
Prosthetic Disuse Leads to Lower Balance Confidence in a Long-Term User of a Transtibial Prosthesis	11
The WOUND-Q Function and Symptoms Scales for Chronic Lower Extremity Wounds: A Validation Study	11
New Opportunities for Electric Fields in Promoting Wound Healing: Collective Electrotaxis	10
Re-Ulceration Is Common in Persons with Diabetes and Healed Foot Ulcer After Participant-Driven Education in Group: A Randomized Controlled Trial	10
Dermal Fibroblast Heterogeneity and Its Contribution to the Skin Repair and Regeneration	10

Re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions” by Bull et al.	10
Alpha-1-Antitrypsin Enhances Fat Graft Survival in a Murine Model	9
Approaches for Regenerative Healing of Cutaneous Wound with an Emphasis on Strategies Activating the Wnt/β-Catenin Pathway	9
Artificial Skin Therapies; Strategy for Product Development	9
Targeting Anaerobic Respiration in Pseudomonas aeruginosa with Chlorate Improves Healing of Chronic Wounds	8
A First-in-Human Randomized Clinical Study Investigating the Safety and Tolerability of Stabilized Hypochlorous Acid in Patients with Chronic Leg Ulcers	8
Topical Reconstituted High-Density Lipoproteins Elicit Anti-Inflammatory Effects in Diabetic Wounds	8
The Effect of Telemedicine Interventions on Patients with Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	8
Current Methodologies for Inducing Aligned Myofibers in Tissue Constructs for Skeletal Muscle Tissue Regeneration	8
The Relationship Between Autoimmune Disease and Disease-Modifying Antirheumatic Drugs on Wound Healing	8
Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations	7
Recent Advances in Functional Wound Dressings	7
Moist Wound Healing with Commonly Available Dressings	7
Switching from Galenic to Advanced Dressings or Vacuum Assisted Closure Therapy Can Improve Quality of Life of Patients with Chronic Non-Responsive Pressure Skin Ulcers: Preliminary Data with Italian	7
Testosterone Promotes Nerve Tethering and Acellular Biomaterial Perineural Fibrosis in a Rat Wound Repair Model	7
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions	6
Gelatin Microspheres Loaded with Wharton's Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice	6
A Review of Hypertrophic Scar and Keloid Treatment and Prevention in the Pediatric Population: Where Are We Now?	6
In Vitro,Ex Vivo, andIn VivoApproaches for Investigation of Skin Scarring: Human and Animal Models	6
Chondrocyte Mitochondrial Quality Control: A Novel Insight into Osteoarthritis and Cartilage Regeneration	6
Use of Therapeutic RNAs to Accelerate Wound Healing in Diabetic Rabbit Wounds	6
The Role of Hydrogel Biomaterials in the Intervention of Wound Healing and Skin Regeneration via Exosomes: A Systematic Review and Meta-Analysis of Preclinical Animal Studies	6
Classification of Distinct Endotypes in Human Skin Scarring: S.C.A.R.—A Novel Perspective on Dermal Fibrosis	6
Prediction of Healing Trajectory of Chronic Wounds Using a Machine Learning Approach	6
Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing	6
Bridging the Gap: Contemporary Paradigms in Nerve Scaffolds and Regeneration	6
Wounds and Skin and Soft Tissue Infections in People Who Inject Drugs and the Utility of Syringe Service Programs in Their Management	6
Clinical Measurement of Transepidermal Water Loss	6
Updates on Excisional Procedures for Lymphedema	5
Negative Pressure Wound Therapy: Challenges, Novel Techniques, and Future Perspectives	5
Reporting of Financial Conflicts of Interest in Studies of Placental Membrane Allografts	5
Magnetic Resonance Imaging Techniques in Peripheral Arterial Disease	5
Acellular Scaffolds for Muscle Regeneration: Advances and Challenges	5
A Novel Xenograft Model Demonstrates Human Fibroblast Behavior During Skin Wound Repair and Fibrosis	5
The Effectiveness of 595-nm Pulsed Dye Laser for the Treatment of Bilateral Cleft-Lip Scars in Asian Patients: A 6-Month Prospective, Randomized, Self-Controlled Trial	5
Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair	5
Treatment of Surgical Scars with Fractional Carbon Dioxide (CO₂) Laser: A Randomized Controlled Trial	5
AI-Powered Image-Based Assessment of Pressure Injuries Using You Only Look once (YOLO) Version 8 Models	5
Deferoxamine to Minimize Fibrosis During Radiation Therapy	5
Strategies to Minimize Surgical Scarring: Translation of Lessons Learned from Bedside to Bench and Back	4
Cerium Nitrate Treatment in the Management of Burns	4
Comparison of “Semiocclusive Dressing” Treatment Using Plastic Wrap or Low-Adherent Absorbent Wound Dressings Versus Occlusive Dressing Treatment for Stage III/IV Pressure Injuries in the Inflammatory	4
Current Understanding of Pathological Mechanisms of Lymphedema	4
HMGB1 Accelerates Wound Healing by Promoting the Differentiation of Epidermal Stem Cells via the “HMGB1-TLR4-Wnt/Notch” Axis	4
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Advances in Wound Care	4
Antimicrobial Peptides for Diabetic Wound Healing: Preclinical and Clinical Studies	4
Assessment of Patient-Reported Outcomes for Closed-Incision Negative Pressure Therapy with Wide-Coverage Dressings in Simple Mastectomy and Immediate Implant-Based Breast Reconstruction	4
Exploring the Overlooked Roles and Mechanisms of Fibroblasts in the Foreign Body Response	4
Modulation of Lymphangiogenesis in Incisional Murine Diabetic Wound Healing Using Negative Pressure Wound Therapy	4
Pharmaceutical Prophylaxis of Scarring with Emphasis on Burns: A Review of Preclinical and Clinical Studies	4
Response to Astrada et al. re: “A Novel Randomized Trial Protocol for Evaluating Wound Healing Interventions”	4
Behind the Scenes of Extracellular Vesicle Therapy for Skin Injuries and Disorders	4
Alginate Formulation for Wound Healing Applications	4
A Prospective, Randomized, Controlled Study to Evaluate the Effectiveness of a Fabric-Based Wireless Electroceutical Dressing Compared to Standard-of-Care Treatment Against Acute Trauma and Burn Wound	4
Re: “How Should Clinical Wound Care and Management Translate to Effective Engineering Standard Testing Requirements from Foam Dressings? Mapping the Existing Gaps and Needs” by Gefen et al.	4