Advances in Nutrition

Article	Citations
Tryptophan Metabolism: A Link Between the Gut Microbiota and Brain	323
Dietary Approaches to Stop Hypertension (DASH) Diet and Blood Pressure Reduction in Adults with and without Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	195
Mechanisms of Action of trans Fatty Acids	134
Ultra-processed Foods and Cardiovascular Diseases: Potential Mechanisms of Action	131
Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health	126
A Systematic Review of the Sources of Dietary Salt Around the World	117
A Systematic Review of Salt Reduction Initiatives Around the World: A Midterm Evaluation of Progress Towards the 2025 Global Non-Communicable Diseases Salt Reduction Target	114
The Role of the Gut Microbiota in Dietary Interventions for Depression and Anxiety	106
The Dietary Inflammatory Index and Human Health: An Umbrella Review of Meta-Analyses of Observational Studies	96
Intake of Sugar-Sweetened and Low-Calorie Sweetened Beverages and Risk of Cardiovascular Disease: A Meta-Analysis and Systematic Review	96
Effects of Popular Diets on Anthropometric and Cardiometabolic Parameters: An Umbrella Review of Meta-Analyses of Randomized Controlled Trials	94
Fermented Dairy Products, Probiotic Supplementation, and Cardiometabolic Diseases: A Systematic Review and Meta-analysis	88
Association of Vitamin D Status with SARS-CoV-2 Infection or COVID-19 Severity: A Systematic Review and Meta-analysis	83
Roles of the Polyphenol–Gut Microbiota Interaction in Alleviating Colitis and Preventing Colitis-Associated Colorectal Cancer	76
Fish Consumption and the Risk of Chronic Disease: An Umbrella Review of Meta-Analyses of Prospective Cohort Studies	76
Effects of Polyphenols in a Mediterranean Diet on Symptoms of Depression: A Systematic Literature Review	74
Perspective: Proposed Harmonized Nutrient Reference Values for Populations	74
Neuroprotective Potential of Ellagic Acid: A Critical Review	69
Retinol, Retinoic Acid, and Retinol-Binding Protein 4 are Differentially Associated with Cardiovascular Disease, Type 2 Diabetes, and Obesity: An Overview of Human Studies	69
Adaptation of the Gut Microbiota to Modern Dietary Sugars and Sweeteners	69
Perspective: The Importance of Water Security for Ensuring Food Security, Good Nutrition, and Well-being	68
Mediterranean Diet and Telomere Length: A Systematic Review and Meta-Analysis	65
Dose–Response Relation between Tea Consumption and Risk of Cardiovascular Disease and All-Cause Mortality: A Systematic Review and Meta-Analysis of Population-Based Studies	64
The Effects of Diets Enriched in Monounsaturated Oleic Acid on the Management and Prevention of Obesity: a Systematic Review of Human Intervention Studies	63
Systematic Review of Dietary Patterns and Sustainability in the United States	60

Tea Consumption and Risk of Cancer: An Umbrella Review and Meta-Analysis of Observational Studies	59
The Prebiotic Potential of Inulin-Type Fructans: A Systematic Review	59
Healthy Food Prescription Programs and their Impact on Dietary Behavior and Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis	58
Nutrition-Sensitive Agriculture: A Systematic Review of Impact Pathways to Nutrition Outcomes	58
Fueling Gut Microbes: A Review of the Interaction between Diet, Exercise, and the Gut Microbiota in Athletes	58
Coronavirus Disease 2019 (COVID-19) and Nutritional Status: The Missing Link?	57
Perspective: Design and Conduct of Human Nutrition Randomized Controlled Trials	55
Does Personalized Nutrition Advice Improve Dietary Intake in Healthy Adults? A Systematic Review of Randomized Controlled Trials	55
Effects of Dietary Patterns on Biomarkers of Inflammation and Immune Responses: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	54
Effects of Dose and Duration of Zinc Interventions on Risk Factors for Type 2 Diabetes and Cardiovascular Disease: A Systematic Review and Meta-Analysis	54
Exosomes in Food: Health Benefits and Clinical Relevance in Diseases	53
Probiotics Contribute to Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis	53
Impact of Nationwide Lockdowns Resulting from the First Wave of the COVID-19 Pandemic on Food Intake, Eating Behaviors, and Diet Quality: A Systematic Review	52
Impact of Nutrition on Telomere Health: Systematic Review of Observational Cohort Studies and Randomized Clinical Trials	50
Dietary Diversity Indicators and Their Associations with Dietary Adequacy and Health Outcomes: A Systematic Scoping Review	49
Preventing Respiratory Tract Infections by Synbiotic Interventions: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	48
Nut Consumption for Cognitive Performance: A Systematic Review	48
The “Virtual Digital Twins” Concept in Precision Nutrition	48
Nutritional Metabolomics and the Classification of Dietary Biomarker Candidates: A Critical Review	47
Female Fertility and the Nutritional Approach: The Most Essential Aspects	47
Perspective: Metabotyping—A Potential Personalized Nutrition Strategy for Precision Prevention of Cardiometabolic Disease	47
Healthy Aging—Nutrition Matters: Start Early and Screen Often	46
Prognostic Potential of the Preoperative Controlling Nutritional Status (CONUT) Score in Predicting Survival of Patients with Cancer: A Systematic Review	46
Association of Dietary Fiber, Fruit, and Vegetable Consumption with Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis	45
Perspective: The Convergence of Coronavirus Disease 2019 (COVID-19) and Food Insecurity in the United States	44
Perspective: Time-Restricted Eating Compared with Caloric Restriction: Potential Facilitators and Barriers of Long-Term Weight Loss Maintenance	44
Impact of α-Linolenic Acid, the Vegetable ω-3 Fatty Acid, on Cardiovascular Disease and Cognition	43
Consumption of Fish and ω-3 Fatty Acids and Cancer Risk: An Umbrella Review of Meta-Analyses of Observational Studies	43
Prophylactic Probiotic Supplementation for Preterm Neonates—A Systematic Review and Meta-Analysis of Nonrandomized Studies	43
Vitamin B-6-Induced Neuropathy: Exploring the Mechanisms of Pyridoxine Toxicity	42
Intake of Various Food Groups and Risk of Breast Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies	42
Higher Mushroom Consumption Is Associated with Lower Risk of Cancer: A Systematic Review and Meta-Analysis of Observational Studies	42
Chronotype Differences in Energy Intake, Cardiometabolic Risk Parameters, Cancer, and Depression: A Systematic Review with Meta-Analysis of Observational Studies	42
Perspective: Whole and Refined Grains and Health—Evidence Supporting “Make Half Your Grains Whole”	42
Vegetable and Fruit Consumption and Prognosis Among Cancer Survivors: A Systematic Review and Meta-Analysis of Cohort Studies	42
Effects of Dietary Glycemic Index and Glycemic Load on Cardiometabolic and Reproductive Profiles in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis of Randomized Controlled	42
Perspective: Soy-based Meat and Dairy Alternatives, Despite Classification as Ultra-processed Foods, Deliver High-quality Nutrition on Par with Unprocessed or Minimally Processed Animal-based Counterp	41
Western Dietary Pattern Antioxidant Intakes and Oxidative Stress: Importance During the SARS-CoV-2/COVID-19 Pandemic	41
Perspective: Childhood Obesity Requires New Strategies for Prevention	40
Dietary Factors and Neurodegenerative Disorders: An Umbrella Review of Meta-Analyses of Prospective Studies	40
The Nutritional Composition and Energy Content of Donor Human Milk: A Systematic Review	39
Can Children Catch up from the Consequences of Undernourishment? Evidence from Child Linear Growth, Developmental Epigenetics, and Brain and Neurocognitive Development	39
Racial-Ethnic Disparities in Obesity and Biological, Behavioral, and Sociocultural Influences in the United States: A Systematic Review	39
Intake of Nuts or Nut Products Does Not Lead to Weight Gain, Independent of Dietary Substitution Instructions: A Systematic Review and Meta-Analysis of Randomized Trials	39
Associations between Maternal Dietary Patterns and Perinatal Outcomes: A Systematic Review and Meta-Analysis of Cohort Studies	39
Perspective: Vegan Diets for Older Adults? A Perspective On the Potential Impact On Muscle Mass and Strength	39
The Impact of Low Advanced Glycation End Products Diet on Metabolic Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials	38
Potential Cardiometabolic Health Benefits of Full-Fat Dairy: The Evidence Base	38
Gut Microbiota-Derived Trimethylamine N-Oxide and Kidney Function: A Systematic Review and Meta-Analysis	36
Diet Regulation of Long-Chain PUFA Synthesis: Role of Macronutrients, Micronutrients, and Polyphenols on Δ-5/Δ-6 Desaturases and Elongases 2/5	36

Dietary Intake and Circulating Concentrations of Carotenoids and Risk of Type 2 Diabetes: A Dose-Response Meta-Analysis of Prospective Observational Studies	36
Perspective: The Potential Role of Circulating Lysophosphatidylcholine in Neuroprotection against Alzheimer Disease	36
Optimizing Adult Protein Intake During Catabolic Health Conditions	35
Food Insecurity and Cognitive Function in Middle to Older Adulthood: A Systematic Review	35
Association of Total Nut, Tree Nut, Peanut, and Peanut Butter Consumption with Cancer Incidence and Mortality: A Comprehensive Systematic Review and Dose-Response Meta-Analysis of Observational Studie	35
Placental Angiogenesis in Mammals: A Review of the Regulatory Effects of Signaling Pathways and Functional Nutrients	35
Water Security and Nutrition: Current Knowledge and Research Opportunities	35
Vitamin D and Multiple Health Outcomes: An Umbrella Review of Observational Studies, Randomized Controlled Trials, and Mendelian Randomization Studies	35
To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease	34
Carotenoid Intake and Circulating Carotenoids Are Inversely Associated with the Risk of Bladder Cancer: A Dose-Response Meta-analysis	34
Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome	34
Intake of ω-6 Polyunsaturated Fatty Acid-Rich Vegetable Oils and Risk of Lifestyle Diseases	34
Perspective: The Saturated Fat–Unsaturated Oil Dilemma: Relations of Dietary Fatty Acids and Serum Cholesterol, Atherosclerosis, Inflammation, Cancer, and All-Cause Mortality	33
A Comprehensive Systematic Review of the Effects of Naringenin, a Citrus-Derived Flavonoid, on Risk Factors for Nonalcoholic Fatty Liver Disease	33
The Mediterranean Dietary Pattern and Inflammation in Older Adults: A Systematic Review and Meta-analysis	33
Criterion-Related Validity of Spectroscopy-Based Skin Carotenoid Measurements as a Proxy for Fruit and Vegetable Intake: A Systematic Review	33
Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?	33
Perspective: Big Data and Machine Learning Could Help Advance Nutritional Epidemiology	33
Nutrition, Immunosenescence, and Infectious Disease: An Overview of the Scientific Evidence on Micronutrients and on Modulation of the Gut Microbiota	32
Anemia, Iron Status, and HIV: A Systematic Review of the Evidence	32
Kidney Stone Prevention	32
The Effects of Natural and Synthetic Blue Dyes on Human Health: A Review of Current Knowledge and Therapeutic Perspectives	31
Reproducibility of A Posteriori Dietary Patterns across Time and Studies: A Scoping Review	30
Dietary Approaches to Improve Efficacy and Control Side Effects of Levodopa Therapy in Parkinson's Disease: A Systematic Review	30
Dietary Potassium Intake and Risk of Chronic Kidney Disease Progression in Predialysis Patients with Chronic Kidney Disease: A Systematic Review	30
Perspective: Classifying Orthorexia Nervosa as a New Mental Illness—Much Discussion, Little Evidence	30
Ethnic Differences in Iron Status	29
Effect of Dietary and Supplemental Lycopene on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis	29
Adherence to the Mediterranean Diet, Five-Year Weight Change, and Risk of Overweight and Obesity: A Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies	29
The Effect of Lutein/Zeaxanthin Intake on Human Macular Pigment Optical Density: A Systematic Review and Meta-Analysis	29
The Potential Impact of Climate Change on the Micronutrient-Rich Food Supply	29
Perspective: How to Develop Nutrient Profiling Models Intended for Global Use: A Manual	29
Systematic Review of Beef Protein Effects on Gut Microbiota: Implications for Health	29
Consumption of Nuts and Seeds and Health Outcomes Including Cardiovascular Disease, Diabetes and Metabolic Disease, Cancer, and Mortality: An Umbrella Review	28
Caffeinated Coffee Consumption and Health Outcomes in the US Population: A Dose–Response Meta-Analysis and Estimation of Disease Cases and Deaths Avoided	28
Resveratrol: Evidence for Its Nephroprotective Effect in Diabetic Nephropathy	28
Dairy Product Consumption and Cardiovascular Health: A Systematic Review and Meta-analysis of Prospective Cohort Studies	28
Chronotype Differences in Body Composition, Dietary Intake and Eating Behavior Outcomes: A Scoping Systematic Review	27
Whole-Fat or Reduced-Fat Dairy Product Intake, Adiposity, and Cardiometabolic Health in Children: A Systematic Review	26
Cross-Kingdom Regulation by Plant microRNAs Provides Novel Insight into Gene Regulation	26
Flavan-3-ols and Cardiometabolic Health: First Ever Dietary Bioactive Guideline	26
Perspective: Characterization of Dietary Supplements Containing Calcium and Magnesium and Their Respective Ratio—Is a Rising Ratio a Cause for Concern?	26
Unhealthy Food and Beverage Consumption in Children and Risk of Overweight and Obesity: A Systematic Review and Meta-Analysis	25
Dietary Antioxidants and Risk of Parkinson’s Disease: A Systematic Review and Dose–Response Meta-analysis of Observational Studies	25
Endocrine Cephalic Phase Responses to Food Cues: A Systematic Review	25
Perspective: Plant-Based Eating Pattern for Type 2 Diabetes Prevention and Treatment: Efficacy, Mechanisms, and Practical Considerations	24
Perspective: Prospects for Nutraceutical Support of Intestinal Barrier Function	24
Impact of Meal Frequency on Anthropometric Outcomes: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials	24
Perspective: Identifying Ultra-Processed Plant-Based Milk Alternatives in the USDA Branded Food Products Database	24
Dietary Intake of Homocysteine Metabolism-Related B-Vitamins and the Risk of Stroke: A Dose-Response Meta-Analysis of Prospective Studies	24
Machine Learning in Nutrition Research	24
The Effect of Aerobic and Resistance Training and Combined Exercise Modalities on Subcutaneous Abdominal Fat: A Systematic Review and Meta-analysis of Randomized Clinical Trials	24
High-Fat Ketogenic Diets and Physical Performance: A Systematic Review	24
Dietary Assessment Methods to Estimate (Poly)phenol Intake in Epidemiological Studies: A Systematic Review	24
Use of the Healthy Eating Index in Intervention Studies for Cardiometabolic Risk Conditions: A Systematic Review	24
Maternal Inositol Status and Neural Tube Defects: A Role for the Human Yolk Sac in Embryonic Inositol Delivery?	24
Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis	23
Perspective: The Role of Human Breast-Milk Extracellular Vesicles in Child Health and Disease	23
Perspective: Why Whole Grains Should Be Incorporated into Nutrient-Profile Models to Better Capture Nutrient Density	23
Food Insecurity among American Indian and Alaska Native People: A Scoping Review to Inform Future Research and Policy Needs	23
Effects of Whole Grain Intake, Compared with Refined Grain, on Appetite and Energy Intake: A Systematic Review and Meta-Analysis	23
Western Dietary Patterns, Foods, and Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Prospective Cohort Studies	23
Are There Benefits from the Use of Fish Oil Supplements in Athletes? A Systematic Review	23
Total, Dietary, and Supplemental Magnesium Intakes and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies	23
Calorie Restriction as a New Treatment of Inflammatory Diseases	22
A Systematic Review and Meta-Analysis of Validation Studies Performed on Dietary Record Apps	22
Perspective: Evidence before Enthusiasm—A Critical Review of the Potential Cardiovascular Benefits of Vitamin K	22
Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects	22
Perspective: Measuring Sweetness in Foods, Beverages, and Diets: Toward Understanding the Role of Sweetness in Health	22
Validity of Body-Composition Methods across Racial and Ethnic Populations	22
Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions	22
Perspective: Creatine, a Conditionally Essential Nutrient: Building the Case	22
Evaluating the Effects of Dietary Interventions on Disease Progression and Symptoms of Adults with Multiple Sclerosis: An Umbrella Review	22
Skeletal Muscle Disuse Atrophy and the Rehabilitative Role of Protein in Recovery from Musculoskeletal Injury	22
Back to the Roots: Revisiting the Use of the Fiber-Rich Cichorium intybus L. Taproots	21
A Critical Review of Multimodal Interventions for Cachexia	21
Association of Consumption of Sugar-Sweetened Beverages or Artificially Sweetened Beverages with Mortality: A Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies	21
Perspective: Unpacking the Wicked Challenges for Alternative Proteins in the United States: Can Highly Processed Plant-Based and Cell-Cultured Food and Beverage Products Support Healthy and Sustainabl	21
Perspective: The Role of Beverages as a Source of Nutrients and Phytonutrients	21
Effects of Total Red Meat Intake on Glycemic Control and Inflammatory Biomarkers: A Meta-Analysis of Randomized Controlled Trials	20

Unsaturated Fatty Acids in Mental Disorders: An Umbrella Review of Meta‐Analyses	20
Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review	20
Factors that Moderate the Effect of Nitrate Ingestion on Exercise Performance in Adults: A Systematic Review with Meta-Analyses and Meta-Regressions	20
Perspective: Application of N-of-1 Methods in Personalized Nutrition Research	20
Perspective: Time-Restricted Eating—Integrating the What with the When	20
Potential Roles of Adipocyte Extracellular Vesicle–Derived miRNAs in Obesity-Mediated Insulin Resistance	20
Vitamin B-12 and the Gastrointestinal Microbiome: A Systematic Review	19
Perspective: The High-Folate–Low-Vitamin B-12 Interaction Is a Novel Cause of Vitamin B-12 Depletion with a Specific Etiology—A Hypothesis	19
Impact of Replacement of Individual Dietary SFAs on Circulating Lipids and Other Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials in Humans	19
Pro-biomics: Omics Technologies To Unravel the Role of Probiotics in Health and Disease	19
Comparing the Effects of Docosahexaenoic and Eicosapentaenoic Acids on Inflammation Markers Using Pairwise and Network Meta-Analyses of Randomized Controlled Trials	19
Effectiveness and Feasibility of Taxing Salt and Foods High in Sodium: A Systematic Review of the Evidence	19
Effects of Exogenous Ketone Supplementation on Blood Glucose: A Systematic Review and Meta-analysis	19
Perspective: Standards for Research and Reporting on Low-Energy (“Artificial”) Sweeteners	18
Consumption of Dairy Products and the Risk of Overweight or Obesity, Hypertension, and Type 2 Diabetes Mellitus: A Dose–Response Meta-Analysis and Systematic Review of Cohort Studies	18
Sustainability Dimensions of the Mediterranean Diet: A Systematic Review of the Indicators Used and Its Results	18
Exploring the Links between Diet and Inflammation: Dairy Foods as Case Studies	18
Personality, Chrono-nutrition and Cardiometabolic Health: A Narrative Review of the Evidence	18
The Promising Effects of Astaxanthin on Lung Diseases	18
Effect of l-Arginine Supplementation on Blood Pressure in Adults: A Systematic Review and Dose–Response Meta-analysis of Randomized Clinical Trials	18
Perspective: Does Glycemic Index Matter for Weight Loss and Obesity Prevention? Examination of the Evidence on “Fast” Compared with “Slow” Carbs	18
Applying Image-Based Food-Recognition Systems on Dietary Assessment: A Systematic Review	17
Perspective: Defining Carbohydrate Quality for Human Health and Environmental Sustainability	17
Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose–Response Meta-Analysis of Prospective Cohort Studies	17
Social Media and Children's and Adolescents' Diets: A Systematic Review of the Underlying Social and Physiological Mechanisms	17
Valuing the Diversity of Research Methods to Advance Nutrition Science	17
Are Processed Tomato Products as Nutritious as Fresh Tomatoes? Scoping Review on the Effects of Industrial Processing on Nutrients and Bioactive Compounds in Tomatoes	17
Perspective: Striking a Balance between Planetary and Human Health—Is There a Path Forward?	17
Meal Pattern Analysis in Nutritional Science: Recent Methods and Findings	17
Human Milk–Derived Fortifiers Compared with Bovine Milk–Derived Fortifiers in Preterm Infants: A Systematic Review and Meta-Analysis	17
Evaluation of Protein Quality in Humans and Insights on Stable Isotope Approaches to Measure Digestibility – A Review	17
Dietary Patterns and Gut Microbiota: The Crucial Actors in Inflammatory Bowel Disease	16
Timing of Pubertal Milestones in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis	16
Effects of Foods Fortified with Zinc, Alone or Cofortified with Multiple Micronutrients, on Health and Functional Outcomes: A Systematic Review and Meta-Analysis	16
Association between Maternal Choline, Fetal Brain Development, and Child Neurocognition: Systematic Review and Meta-Analysis of Human Studies	16
Healthy plant-based diets improve dyslipidemias, insulin resistance, and inflammation in metabolic syndrome. A narrative review	16
Supplementation of Bovine Colostrum in Inflammatory Bowel Disease: Benefits and Contraindications	16
Carotenoids and Their Health Benefits as Derived via Their Interactions with Gut Microbiota	16
The Efficacy of Ketogenic Therapies in the Clinical Management of People with Neurodegenerative Disease: A Systematic Review	16
Epigenetic Effects of Healthy Foods and Lifestyle Habits from the Southern European Atlantic Diet Pattern: A Narrative Review	16