OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Synthetic Biology is 40. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
LOICA: Integrating Models with Data for Genetic Network Design Automation	89
Stem Loop Mediated Transgene Modulation in Human T Cells	85
Discovering Content through Text Mining for a Synthetic Biology Knowledge System	84
Mobile Translation Systems Generate Genomically Engineered Escherichia coli Cells with Improved Growth Phenotypes	82
Preventing Production Escape Using an Engineered Glucose-Inducible Genetic Circuit	78
The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology	77
Simplified Construction of Engineered Bacillus subtilis Host for Improved Expression of Proteins Harboring Noncanonical Amino Acids	77
Efficient Mutasynthesis of “Non-Natural” Antitubercular Ilamycins with Low Cytotoxicity	66
Synthetic Biology 2.0: The Dawn of a New Era	63
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid	62
Cell-Free Expression of Soluble Leafhopper Proteins from Brochosomes	62
Protease-Responsive Toolkit for Conditional Targeted Protein Degradation	60
In VivoSampling of Intracellular Heterogeneity ofPseudomonas putidaEnables Multiobjective Optimization of Genetic Devices	59
Predicting and Interpreting Protein Developability Via Transfer of Convolutional Sequence Representation	58
Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis	54
An Autocatalytic Peptide Cyclase Improves Fidelity and Yield of Circular Peptides In Vivo and In Vitro	54
Energy Aware Technology Mapping of Genetic Logic Circuits	54
Actomyosin-Driven Division of a Synthetic Cell	53
IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation	50
Construction of an Engineered Escherichia coli with Efficient Chemotactic and Metabolizing Ability toward Tetrathionate	50
Engineered Mutants of a Marine Photosynthetic Purple Nonsulfur Bacterium with Increased Volumetric Productivity of Polyhydroxyalkanoate Bioplastics	50
Targeting Transcriptional and Translational Hindrances in a Modular T7RNAP Expression System in Engineered Pseudomonas putida	49
Control of λ Lysogenic Escherichia coli Cells by Synthetic λ Phage Carrying cI^antisense	48
Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many	48
Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens	47

Cell-Free Protein Synthesis as a Method to Rapidly Screen Machine Learning-Generated Protease Variants	46
A Photoresponsive Homing Endonuclease for Programmed DNA Cleavage	46
Highly Accurate Sequence- and Position-Independent Error Profiling of DNA Synthesis and Sequencing	46
A Logically Reversible Double Feynman Gate with Molecular Engineered Bacteria Arranged in an Artificial Neural Network-Type Architecture	45
Metabolic Engineering of Clostridium tyrobutyricum for High-Yield n-Butanol Production by Increasing Intracellular Reducing Equivalent with NADPH-Dependent 3-Hydroxybutyryl-CoA Dehydroge	45
Issue Publication Information	44
Efficient Genome Editing in Most Staphylococcus aureus by Using the Restriction-Modification System Silent CRISPR-Cas9 Toolkit	43
Improved Cell-Free Transcription–Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis	43
Synthetic Biology Design as a Paradigm Shift toward Manufacturing Affordable Adeno-Associated Virus Gene Therapies	42
Engineering Cyanobacterial Cell Factories for Photosynthetic Production of Fructose	42
Nano-Regulation of Gene Expression in Chlamydomonas reinhardtii: Harnessing AuNPs for Remotely Switchable Lipid Biosynthesis via Antisense Oligonucleotides	42
Desiccated Cyanobacteria Serve As Efficient Plasmid DNA Carriers in Space Flight	41
Lipid Modification and Membrane Localization of Proteins in Cell-Free System	40
Directed Evolution of a SelB Variant that Does Not Require a Selenocysteine Insertion Sequence Element for Function	40
Development of a Recombineering System for the Acetogen Eubacterium limosum with Cas9 Counterselection for Markerless Genome Engineering	40