OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Synthetic Biology is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Robotic DNA Nanostructures	102
Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning	80
An Automated Model Test System for Systematic Development and Improvement of Gene Expression Models	79
Biosystems Design by Machine Learning	76
Compartmentalizing Cell-Free Systems: Toward Creating Life-Like Artificial Cells and Beyond	70
Transcription-Factor-based Biosensor Engineering for Applications in Synthetic Biology	68
Signal Peptides Generated by Attention-Based Neural Networks	63
Isothermal SARS-CoV-2 Diagnostics: Tools for Enabling Distributed Pandemic Testing as a Means of Supporting Safe Reopenings	62
Engineering Yarrowia lipolytica as a Chassis for De Novo Synthesis of Five Aromatic-Derived Natural Products and Chemicals	55
Application of CRISPR-Cas12a Enhanced Fluorescence Assay Coupled with Nucleic Acid Amplification for the Sensitive Detection of African Swine Fever Virus	55
Cell-free Directed Evolution of a Protease in Microdroplets at Ultrahigh Throughput	55
Statistical Design of Experiments for Synthetic Biology	53
Multicopy Chromosomal Integration Using CRISPR-Associated Transposases	53
Engineering Wired Life: Synthetic Biology for Electroactive Bacteria	52
Improved Production of Malic Acid in Aspergillus niger by Abolishing Citric Acid Accumulation and Enhancing Glycolytic Flux	51
Systematic Quantification of Sequence and Structural Determinants Controlling mRNA stability in Bacterial Operons	50
Synthetic Glycobiology: Parts, Systems, and Applications	50
Bio-SCAN: A CRISPR/dCas9-Based Lateral Flow Assay for Rapid, Specific, and Sensitive Detection of SARS-CoV-2	49
A Unified Dynamic Programming Framework for the Analysis of Interacting Nucleic Acid Strands: Enhanced Models, Scalability, and Speed	48
CRISPR-Mediated Activation of Biosynthetic Gene Clusters for Bioactive Molecule Discovery in Filamentous Fungi	47
CRISPRi-dCas12a: A dCas12a-Mediated CRISPR Interference for Repression of Multiple Genes and Metabolic Engineering in Cyanobacteria	46
Bacteriophage Inspired Growth-Decoupled Recombinant Protein Production in Escherichia coli	45
CRISPR-Cas12a-Assisted Multicolor Biosensor for Semiquantitative Point-of-Use Testing of the Nopaline Synthase Terminator in Genetically Modified Crops by Unaided Eyes	43
Optogenetic Amplification Circuits for Light-Induced Metabolic Control	43
Morphological and Metabolic Engineering of Yarrowia lipolytica to Increase β-Carotene Production	43

Enabling Biological Nitrogen Fixation for Cereal Crops in Fertilized Fields	42
A Dual-Plasmid CRISPR/Cas System for Mycotoxin Elimination in Polykaryotic Industrial Fungi	42
Optimized cDICE for Efficient Reconstitution of Biological Systems in Giant Unilamellar Vesicles	42
Transcription and Translation in Cytomimetic Protocells Perform Most Efficiently at Distinct Macromolecular Crowding Conditions	41
Bottom-Up Construction of a Minimal System for Cellular Respiration and Energy Regeneration	41
Synthetic Virus-like Particles for Glutathione Biosynthesis	40
A Whole-Cell Biosensor for Point-of-Care Detection of Waterborne Bacterial Pathogens	40
Multicopy Targeted Integration for Accelerated Development of High-Producing Chinese Hamster Ovary Cells	39
Cell-Free Gene Expression Dynamics in Synthetic Cell Populations	39
Automated Continuous Evolution of Proteins in Vivo	38
CRISPR-Cas13 System as a Promising and Versatile Tool for Cancer Diagnosis, Therapy, and Research	38
Rational Promoter Engineering Enables Robust Terpene Production in Microalgae	38
A Chemical Switch System to Modulate Chimeric Antigen Receptor T Cell Activity through Proteolysis-Targeting Chimaera Technology	37
Development of Novel Riboswitches for Synthetic Biology in the Green Alga Chlamydomonas	37