OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Synthetic Biology is 37. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Synthetic Biology 2.0: The Dawn of a New Era	128
Mobile Translation Systems Generate Genomically Engineered Escherichia coli Cells with Improved Growth Phenotypes	118
Preventing Production Escape Using an Engineered Glucose-Inducible Genetic Circuit	95
The Japan-UK Synthetic Biology Conference, Spring 2025: Strengthening Global Links to Engineer Biology	86
Highly Accurate Sequence- and Position-Independent Error Profiling of DNA Synthesis and Sequencing	82
Issue Publication Information	78
Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens	74
Stem Loop Mediated Transgene Modulation in Human T Cells	67
Construction of an Engineered Escherichia coli with Efficient Chemotactic and Metabolizing Ability toward Tetrathionate	58
Strategies for Improved Docosahexaenoic Acid Synthesis in Microalgae	58
Nano-Regulation of Gene Expression in Chlamydomonas reinhardtii: Harnessing AuNPs for Remotely Switchable Lipid Biosynthesis via Antisense Oligonucleotides	57
In VivoSampling of Intracellular Heterogeneity ofPseudomonas putidaEnables Multiobjective Optimization of Genetic Devices	55
Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis	55
A Photoresponsive Homing Endonuclease for Programmed DNA Cleavage	53
Metabolic Engineering of Microbial Chassis Cells for d-Pantothenate Production: A Review	53
Efficient Mutasynthesis of “Non-Natural” Antitubercular Ilamycins with Low Cytotoxicity	52
Cell-Free Transcription and Translation Tether Expressed Peptides to Their Encoding Circular DNA	50
Issue Publication Information	50
IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation	48
Engineering Cyanobacterial Cell Factories for Photosynthetic Production of Fructose	44
LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning	43
An Autocatalytic Peptide Cyclase Improves Fidelity and Yield of Circular Peptides In Vivo and In Vitro	42
Lipid Modification and Membrane Localization of Proteins in Cell-Free System	42
A Logically Reversible Double Feynman Gate with Molecular Engineered Bacteria Arranged in an Artificial Neural Network-Type Architecture	42
Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many	42

Targeting Transcriptional and Translational Hindrances in a Modular T7RNAP Expression System in Engineered Pseudomonas putida	41
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid	41
Simplified Construction of Engineered Bacillus subtilis Host for Improved Expression of Proteins Harboring Noncanonical Amino Acids	41
Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology	41
Protease-Responsive Toolkit for Conditional Targeted Protein Degradation	40
Improved Cell-Free Transcription–Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis	40
Development of a Recombineering System for the Acetogen Eubacterium limosum with Cas9 Counterselection for Markerless Genome Engineering	39
Energy Aware Technology Mapping of Genetic Logic Circuits	39
Preclinical Evaluation of Synthetic Biology-Driven Engineered Escherichia coli Nissle 1917 as a Living Therapeutic for Sustained L-DOPA Delivery	38
Desiccated Cyanobacteria Serve As Efficient Plasmid DNA Carriers in Space Flight	38
Synthetic Biology Design as a Paradigm Shift toward Manufacturing Affordable Adeno-Associated Virus Gene Therapies	38
LOICA: Integrating Models with Data for Genetic Network Design Automation	38
Recent Advances in the Biological Synthesis of l-Tyrosine Derivatives by Genetically Engineered Microbes	37
Discovering Content through Text Mining for a Synthetic Biology Knowledge System	37
Plasmid Copy Number Engineering Accelerates Fungal Polyketide Discovery upon Unnatural Polyketide Biosynthesis	37