OOIR: Observatory of International Research

Papers

(The H4-Index of ACS Synthetic Biology is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
An Autocatalytic Peptide Cyclase Improves Fidelity and Yield of Circular Peptides In Vivo and In Vitro	77
Engineering a Novel Acetyl-CoA Pathway for Efficient Biosynthesis of Acetyl-CoA-Derived Compounds	74
Predicting and Interpreting Protein Developability Via Transfer of Convolutional Sequence Representation	74
LevSeq: Rapid Generation of Sequence-Function Data for Directed Evolution and Machine Learning	73
LOICA: Integrating Models with Data for Genetic Network Design Automation	71
Optimal LentiCRISPR-Based System for Sequential CRISPR/Cas9 Screens	64
DisGUVery: A Versatile Open-Source Software for High-Throughput Image Analysis of Giant Unilamellar Vesicles	60
Stem Loop Mediated Transgene Modulation in Human T Cells	59
Energy Aware Technology Mapping of Genetic Logic Circuits	59
Improved Cell-Free Transcription–Translation Reactions in Microfluidic Chemostats Augmented with Hydrogel Membranes for Continuous Small Molecule Dialysis	59
Discovering Content through Text Mining for a Synthetic Biology Knowledge System	55
Bacteria Engineered to Produce Serotonin Modulate Host Intestinal Physiology	54
Desiccated Cyanobacteria Serve As Efficient Plasmid DNA Carriers in Space Flight	53
Plasmid Copy Number Engineering Accelerates Fungal Polyketide Discovery upon Unnatural Polyketide Biosynthesis	53
Control of λ Lysogenic Escherichia coli Cells by Synthetic λ Phage Carrying cI^antisense	50
Preventing Production Escape Using an Engineered Glucose-Inducible Genetic Circuit	50
Mobile Translation Systems Generate Genomically Engineered Escherichia coli Cells with Improved Growth Phenotypes	50
Highly Accurate Sequence- and Position-Independent Error Profiling of DNA Synthesis and Sequencing	49
Nano-Regulation of Gene Expression in Chlamydomonas reinhardtii: Harnessing AuNPs for Remotely Switchable Lipid Biosynthesis via Antisense Oligonucleotides	49
Simplified Construction of Engineered Bacillus subtilis Host for Improved Expression of Proteins Harboring Noncanonical Amino Acids	49
Engineered Mutants of a Marine Photosynthetic Purple Nonsulfur Bacterium with Increased Volumetric Productivity of Polyhydroxyalkanoate Bioplastics	47
Cell-Free Expression of Soluble Leafhopper Proteins from Brochosomes	46
IWBDA 2022: Toward a Modular Future of Synthetic Biology Driven by Bio-Design Automation	46
Synthetic Biology 2.0: The Dawn of a New Era	46
A Photoresponsive Homing Endonuclease for Programmed DNA Cleavage	45

Targeting Transcriptional and Translational Hindrances in a Modular T7RNAP Expression System in Engineered Pseudomonas putida	45
Hybrid Methylotrophic Pathway in Serratia marcescens for Sustainable Terpenoid Biosynthesis	45
A Logically Reversible Double Feynman Gate with Molecular Engineered Bacteria Arranged in an Artificial Neural Network-Type Architecture	44
Engineered l-Lactate Responding Promoter System Operating in Glucose-Rich and Anoxic Environments	43
Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many	42
Cell Free Bacteriophage Synthesis from Engineered Strains Improves Yield	41
Parameterized Computational Framework for the Description and Design of Genetic Circuits of Morphogenesis Based on Contact-Dependent Signaling and Changes in Cell–Cell Adhesion	41
Efficient Mutasynthesis of “Non-Natural” Antitubercular Ilamycins with Low Cytotoxicity	39
Efficient CRISPR/Cas12a-Based Genome-Editing Toolbox for Metabolic Engineering in Methanococcus maripaludis	39
Synthetic Biology Design as a Paradigm Shift toward Manufacturing Affordable Adeno-Associated Virus Gene Therapies	39
Combining Chemical Catalysis with Enzymatic Steps for the Synthesis of the Artemisinin Precursor Dihydroartemisinic Acid	38
Efficient Genome Editing in Most Staphylococcus aureus by Using the Restriction-Modification System Silent CRISPR-Cas9 Toolkit	38
Development of a Recombineering System for the Acetogen Eubacterium limosum with Cas9 Counterselection for Markerless Genome Engineering	38
Protease-Responsive Toolkit for Conditional Targeted Protein Degradation	38