Translational Psychiatry

Papers
(The TQCC of Translational Psychiatry is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer’s disease245
Mapping global prevalence of depression among postpartum women239
Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review192
Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder156
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease139
Psycho-social factors associated with mental resilience in the Corona lockdown134
Public mental health problems during COVID-19 pandemic: a large-scale meta-analysis of the evidence113
Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders110
Neuronal hyperexcitability in Alzheimer’s disease: what are the drivers behind this aberrant phenotype?107
How machine-learning recommendations influence clinician treatment selections: the example of antidepressant selection104
Depression, anxiety and associated factors among Chinese adolescents during the COVID-19 outbreak: a comparison of two cross-sectional studies102
Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109)89
Mild behavioral impairment and its relation to tau pathology in preclinical Alzheimer’s disease88
Mental disorders following COVID-19 and other epidemics: a systematic review and meta-analysis87
Antidepressants fluoxetine and amitriptyline induce alterations in intestinal microbiota and gut microbiome function in rats exposed to chronic unpredictable mild stress84
A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches84
Impact of COVID-19 lockdown on mental health in Germany: longitudinal observation of different mental health trajectories and protective factors83
Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders82
Clinical, gut microbial and neural effects of a probiotic add-on therapy in depressed patients: a randomized controlled trial76
Efficacy and safety of clozapine in psychotic disorders—a systematic quantitative meta-review75
The association between depression and metabolic syndrome and its components: a bidirectional two-sample Mendelian randomization study73
Recovering from depression with repetitive transcranial magnetic stimulation (rTMS): a systematic review and meta-analysis of preclinical studies73
Machine learning for suicide risk prediction in children and adolescents with electronic health records70
Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression70
COVID-19 and risk of neurodegenerative disorders: A Mendelian randomization study69
The effects of social isolation stress and discrimination on mental health68
Plasma lipidome is dysregulated in Alzheimer’s disease and is associated with disease risk genes67
Catalpol ameliorates depressive-like behaviors in CUMS mice via oxidative stress-mediated NLRP3 inflammasome and neuroinflammation66
Gut microbiota link dietary fiber intake and short-chain fatty acid metabolism with eating behavior65
Altered resting-state functional connectome in major depressive disorder: a mega-analysis from the PsyMRI consortium65
Sleep in Alzheimer’s disease: a systematic review and meta-analysis of polysomnographic findings64
Transdiagnostic dimensions of psychopathology explain individuals’ unique deviations from normative neurodevelopment in brain structure63
Neuroinflammation in schizophrenia: the role of nuclear factor kappa B63
Biallelic mutations in the death domain of PIDD1 impair caspase-2 activation and are associated with intellectual disability62
Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents60
A randomised, double-blind, sham-controlled trial of deep brain stimulation of the bed nucleus of the stria terminalis for treatment-resistant obsessive-compulsive disorder60
Parental characteristics and offspring mental health and related outcomes: a systematic review of genetically informative literature60
Probiotics-induced changes in gut microbial composition and its effects on cognitive performance after stress: exploratory analyses59
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods59
Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors59
Worldwide prevalence of suicidal ideation and suicide plan among people with schizophrenia: a meta-analysis and systematic review of epidemiological surveys58
“GrimAge,” an epigenetic predictor of mortality, is accelerated in major depressive disorder58
Characterization of gut microbiome in mice model of depression with divergent response to escitalopram treatment58
Psychological and biological resilience modulates the effects of stress on epigenetic aging56
Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic56
Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis56
Gray and white matter morphology in substance use disorders: a neuroimaging systematic review and meta-analysis56
Meta-analysis of probability estimates of worldwide variation of CYP2D6 and CYP2C1956
Spontaneous and deliberate creative cognition during and after psilocybin exposure55
Fractionating autism based on neuroanatomical normative modeling55
Personalized machine learning of depressed mood using wearables55
Establishing a clinical service to prevent psychosis: What, how and when? Systematic review55
From mechanisms to markers: novel noninvasive EEG proxy markers of the neural excitation and inhibition system in humans54
Glutamate and microglia activation as a driver of dendritic apoptosis: a core pathophysiological mechanism to understand schizophrenia53
Immunological causes of obsessive-compulsive disorder: is it time for the concept of an “autoimmune OCD” subtype?53
Mindfulness practice for protecting mental health during the COVID-19 pandemic53
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression53
Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study53
Network analysis of depressive symptoms in Hong Kong residents during the COVID-19 pandemic53
Reducing intrusive memories after trauma via a brief cognitive task intervention in the hospital emergency department: an exploratory pilot randomised controlled trial51
Socioeconomic status, BMI, and brain development in children51
Late-life depression and increased risk of dementia: a longitudinal cohort study51
The role of the immune system in posttraumatic stress disorder51
Ventromedial prefrontal cortex/anterior cingulate cortex Glx, glutamate, and GABA levels in medication-free major depressive disorder51
Gut microbial taxa elevated by dietary sugar disrupt memory function51
Integrative analysis of genome-wide association studies identifies novel loci associated with neuropsychiatric disorders50
Structural and functional deficits and couplings in the cortico-striato-thalamo-cerebellar circuitry in social anxiety disorder50
A diet high in sugar and fat influences neurotransmitter metabolism and then affects brain function by altering the gut microbiota50
Efficacy and tolerability of repetitive transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder in adults: a systematic review and network meta-analysis50
Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression49
Melatonin’s neuroprotective role in mitochondria and its potential as a biomarker in aging, cognition and psychiatric disorders49
Comorbidities in autism spectrum disorder and their etiologies49
Neurosteroid allopregnanolone (3α,5α-THP) inhibits inflammatory signals induced by activated MyD88-dependent toll-like receptors49
Proteomics analysis of the gut–brain axis in a gut microbiota-dysbiosis model of depression48
Insulinopathies of the brain? Genetic overlap between somatic insulin-related and neuropsychiatric disorders48
Gene expression studies in Depression development and treatment: an overview of the underlying molecular mechanisms and biological processes to identify biomarkers47
Consolidation/reconsolidation therapies for the prevention and treatment of PTSD and re-experiencing: a systematic review and meta-analysis47
Gut microbiota, innate immune pathways, and inflammatory control mechanisms in patients with major depressive disorder46
Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset46
Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression46
Theta burst stimulation for the acute treatment of major depressive disorder: A systematic review and meta-analysis46
COVID-19 restrictions and age-specific mental health—U.S. probability-based panel evidence46
Ibudilast, a neuroimmune modulator, reduces heavy drinking and alcohol cue-elicited neural activation: a randomized trial46
The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: 46
Fronto-limbic neural variability as a transdiagnostic correlate of emotion dysregulation45
Compassion toward others and self-compassion predict mental and physical well-being: a 5-year longitudinal study of 1090 community-dwelling adults across the lifespan45
The effects of early life adversity on children’s mental health and cognitive functioning45
A schizophrenia subgroup with elevated inflammation displays reduced microglia, increased peripheral immune cell and altered neurogenesis marker gene expression in the subependymal zone44
Transcription factor 4 and its association with psychiatric disorders44
A machine learning algorithm to differentiate bipolar disorder from major depressive disorder using an online mental health questionnaire and blood biomarker data44
Cytokines and tryptophan metabolites can predict depressive symptoms in pregnancy44
Amyloid-beta uptake by blood monocytes is reduced with ageing and Alzheimer’s disease44
Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations44
Antidepressant side effects and their impact on treatment outcome in people with major depressive disorder: an iSPOT-D report44
Anomalous brain gyrification patterns in major psychiatric disorders: a systematic review and transdiagnostic integration44
Neural contributors to trauma resilience: a review of longitudinal neuroimaging studies43
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder43
Title: “Labels Matter: Is it stress or is it Trauma?”42
Serum d-serine levels are altered in early phases of Alzheimer’s disease: towards a precocious biomarker42
Glutamatergic dysfunction in Schizophrenia42
The IL-6 antagonist tocilizumab is associated with worse depression and related symptoms in the medically ill42
Alterations of kynurenine pathway in alcohol use disorder and abstinence: a link with gut microbiota, peripheral inflammation and psychological symptoms42
Transcriptome-wide association study identifies new susceptibility genes and pathways for depression41
The patterns of family genetic risk scores for eleven major psychiatric and substance use disorders in a Swedish national sample41
Anxiety and depressive symptoms in college students during the late stage of the COVID-19 outbreak: a network approach41
Magnetic resonance imaging for individual prediction of treatment response in major depressive disorder: a systematic review and meta-analysis40
Social support mediates the influence of cerebellum functional connectivity strength on postpartum depression and postpartum depression with anxiety40
Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer’s disease risk40
Optimizing prediction of response to antidepressant medications using machine learning and integrated genetic, clinical, and demographic data40
Sensory over-responsivity is related to GABAergic inhibition in thalamocortical circuits40
Gamma oscillations predict pro-cognitive and clinical response to auditory-based cognitive training in schizophrenia39
Enduring neurobehavioral effects induced by microbiota depletion during the adolescent period39
Longitudinal plasma phosphorylated tau 181 tracks disease progression in Alzheimer’s disease39
Anomaly detection to predict relapse risk in schizophrenia39
Brain network dysfunctions in addiction: a meta-analysis of resting-state functional connectivity39
Peripheral immune cell reactivity and neural response to reward in patients with depression and anhedonia39
Emerging behavioral and neuroimaging biomarkers for early and accurate characterization of autism spectrum disorders: a systematic review38
Cannabis, schizophrenia genetic risk, and psychotic experiences: a cross-sectional study of 109,308 participants from the UK Biobank38
Mental health and music engagement: review, framework, and guidelines for future studies38
Influence of social isolation caused by coronavirus disease 2019 (COVID-19) on the psychological characteristics of hospitalized schizophrenia patients: a case-control study38
MicroRNA-dependent control of neuroplasticity in affective disorders38
Natural Language Processing markers in first episode psychosis and people at clinical high-risk38
Genetic association study of childhood aggression across raters, instruments, and age37
Sex differences in the neuroanatomy of alcohol dependence: hippocampus and amygdala subregions in a sample of 966 people from the ENIGMA Addiction Working Group37
Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic interventions37
Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression37
Translational evidence for lithium-induced brain plasticity and neuroprotection in the treatment of neuropsychiatric disorders37
Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients36
Contributing factors to advanced brain aging in depression and anxiety disorders36
Gut microbial biomarkers for the treatment response in first-episode, drug-naïve schizophrenia: a 24-week follow-up study36
Brain dynamics: the temporal variability of connectivity, and differences in schizophrenia and ADHD36
Maternal immune activation induces autism-like changes in behavior, neuroinflammatory profile and gut microbiota in mouse offspring of both sexes36
Plasma phosphorylated-tau181 as a predictive biomarker for Alzheimer’s amyloid, tau and FDG PET status36
Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group36
Identification of inflammatory subgroups of schizophrenia and bipolar disorder patients with HERV-W ENV antigenemia by unsupervised cluster analysis35
The gut microbiome in social anxiety disorder: evidence of altered composition and function35
Cortisol and inflammatory biomarker levels in youths with attention deficit hyperactivity disorder (ADHD): evidence from a systematic review with meta-analysis35
Thalamocortical connectivity is associated with autism symptoms in high-functioning adults with autism and typically developing adults35
Gut microbiota signature in treatment-naïve attention-deficit/hyperactivity disorder35
Intensification of functional neural control on heartbeat dynamics in subclinical depression35
Role of dietary factors in the prevention and treatment for depression: an umbrella review of meta-analyses of prospective studies35
Childhood maltreatment predicts subsequent anxiety symptoms among Chinese adolescents: the role of the tendency of coping styles35
Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics35
A simultaneous [11C]raclopride positron emission tomography and functional magnetic resonance imaging investigation of striatal dopamine binding in autism35
A pilot exploration of multi-omics research of gut microbiome in major depressive disorders34
Acute psychological impact on COVID-19 patients in Hubei: a multicenter observational study34
Functional network alterations differently associated with suicidal ideas and acts in depressed patients: an indirect support to the transition model34
White matter microstructure and its relation to clinical features of obsessive–compulsive disorder: findings from the ENIGMA OCD Working Group34
Exposure to maternal high-fat diet induces extensive changes in the brain of adult offspring34
Obesity and atypical depression symptoms: findings from Mendelian randomization in two European cohorts34
Cortical structure and the risk for Alzheimer’s disease: a bidirectional Mendelian randomization study34
The interplay of dopamine metabolism abnormalities and mitochondrial defects in the pathogenesis of schizophrenia33
Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder33
Cortical and subcortical brain structure in generalized anxiety disorder: findings from 28 research sites in the ENIGMA-Anxiety Working Group33
Predicting treatment response using EEG in major depressive disorder: A machine-learning meta-analysis33
The prevalence of depressive and anxiety symptoms and their associations with quality of life among clinically stable older patients with psychiatric disorders during the COVID-19 pandemic33
Genetics of autism spectrum disorder: an umbrella review of systematic reviews and meta-analyses33
The relationship between synaptic density marker SV2A, glutamate and N-acetyl aspartate levels in healthy volunteers and schizophrenia: a multimodal PET and magnetic resonance spectroscopy brain imagi33
Psychobiotic interventions for anxiety in young people: a systematic review and meta-analysis, with youth consultation32
Enhanced long-term potentiation and impaired learning in mice lacking alternative exon 33 of CaV1.2 calcium channel32
The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors32
Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine32
Cell-type-specific epigenetic effects of early life stress on the brain32
Exploratory drive, fear, and anxiety are dissociable and independent components in foraging mice32
Prevalence and correlates of suicidal ideation and suicide attempts in preadolescent children: A US population-based study32
Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders32
Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue32
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms32
Intraoperative neural signals predict rapid antidepressant effects of deep brain stimulation32
Proteomics of autism and Alzheimer’s mouse models reveal common alterations in mTOR signaling pathway32
Low dose oral ketamine treatment in chronic suicidality: An open-label pilot study32
The self on its axis: a framework for understanding depression31
Barriers to clinical adoption of pharmacogenomic testing in psychiatry: a critical analysis31
Bilateral Habenula deep brain stimulation for treatment-resistant depression: clinical findings and electrophysiological features31
Prevalence of and factors associated with post-traumatic stress disorder among French university students 1 month after the COVID-19 lockdown31
Decentering as a core component in the psychological treatment and prevention of youth anxiety and depression: a narrative review and insight report31
Default-mode and fronto-parietal network connectivity during rest distinguishes asymptomatic patients with bipolar disorder and major depressive disorder31
Neural network of bipolar disorder: Toward integration of neuroimaging and neurocircuit-based treatment strategies31
Zbtb16 regulates social cognitive behaviors and neocortical development31
Insula sub-regions across the psychosis spectrum: morphology and clinical correlates31
Prevalence of poor psychiatric status and sleep quality among frontline healthcare workers during and after the COVID-19 outbreak: a longitudinal study31
The role of the orbitofrontal cortex and the nucleus accumbens for craving in alcohol use disorder30
Conducting double-blind placebo-controlled clinical trials of transcranial alternating current stimulation (tACS)30
Effectiveness of KarXT (xanomeline-trospium) for cognitive impairment in schizophrenia: post hoc analyses from a randomised, double-blind, placebo-controlled phase 2 study30
Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats30
Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions30
A randomised clinical trial of methotrexate points to possible efficacy and adaptive immune dysfunction in psychosis30
Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mendelian randomization 29
Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice29
Deficits in hippocampal-dependent memory across different rodent models of early life stress: systematic review and meta-analysis29
Drug addiction: from bench to bedside29
Psychiatric symptoms and behavioral adjustment during the COVID-19 pandemic: evidence from two population-representative cohorts29
Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task29
Cross-tissue correlations of genome-wide DNA methylation in Japanese live human brain and blood, saliva, and buccal epithelial tissues29
Emerging imaging methods to study whole-brain function in rodent models28
Biological factors influencing depression in later life: role of aging processes and treatment implications28
DNA methylation differences associated with social anxiety disorder and early life adversity28
Correction: Mapping global prevalence of depression among postpartum women28
Understanding complex functional wiring patterns in major depressive disorder through brain functional connectome28
Virtual reality: a powerful technology to provide novel insight into treatment mechanisms of addiction28
Natural language processing for mental health interventions: a systematic review and research framework28
Region-specific elevations of glutamate + glutamine correlate with the sensory symptoms of autism spectrum disorders28
Circulating endocannabinoids and genetic polymorphisms as predictors of posttraumatic stress disorder symptom severity: heterogeneity in a community-based cohort28
Serotonin depletion amplifies distinct human social emotions as a function of individual differences in personality28
Clinical utility of combinatorial pharmacogenomic testing in depression: A Canadian patient- and rater-blinded, randomized, controlled trial28
Exploration of alcohol use disorder-associated brain miRNA–mRNA regulatory networks28
Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder28
Human forebrain organoids reveal connections between valproic acid exposure and autism risk27
The association between latent trauma and brain structure in children27
Obsessive–compulsive symptoms and information seeking during the Covid-19 pandemic27
How do established developmental risk-factors for schizophrenia change the way the brain develops?27
Acute effects of intravenous DMT in a randomized placebo-controlled study in healthy participants27
Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure27
Staging tau pathology with tau PET in Alzheimer’s disease: a longitudinal study27
ECT-induced cognitive side effects are associated with hippocampal enlargement27
Reward and aversion encoding in the lateral habenula for innate and learned behaviours27
Effects of pharmacological treatment on metabolomic alterations in animal models of depression27
Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder27
A review of functional and structural neuroimaging studies to investigate the inner speech model of auditory verbal hallucinations in schizophrenia27
Understanding the psychiatric symptoms of COVID-19: a meta-analysis of studies assessing psychiatric symptoms in Chinese patients with and survivors of COVID-19 and SARS by using the Symptom Checklist27
Genome-wide analysis suggests the importance of vascular processes and neuroinflammation in late-life antidepressant response27
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis27
Synaptic processes and immune-related pathways implicated in Tourette syndrome27
Association between FIASMA psychotropic medications and reduced risk of intubation or death in individuals with psychiatric disorders hospitalized for severe COVID-19: an observational multicenter stu26
The hidden link between circadian entropy and mental health disorders26
Glycosylation and behavioral symptoms in neurological disorders26
Effect of TAAR1/5-HT1A agonist SEP-363856 on REM sleep in humans26
Peripheral level of CD33 and Alzheimer’s disease: a bidirectional two-sample Mendelian randomization study26
Cell-type specific changes in PKC-delta neurons of the central amygdala during alcohol withdrawal26
Alcohol use disorder causes global changes in splicing in the human brain26
Depression treatment response to ketamine: sex-specific role of interleukin-8, but not other inflammatory markers26
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans26
Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations26
Oxytocin treatment attenuates amygdala activity in autism: a treatment-mechanism study with long-term follow-up26
Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation26
Depressive symptoms, anxiety and cognitive impairment: emerging evidence in multiple sclerosis26
Polygenic risk scores for major psychiatric and neurodevelopmental disorders contribute to sleep disturbance in childhood: Adolescent Brain Cognitive Development (ABCD) Study26
Efficacy and practice of facemask use in general population: a systematic review and meta-analysis26
Predicting alcohol use disorder remission: a longitudinal multimodal multi-featured machine learning approach26
Altered relationship between subjective perception and central representation of touch hedonics in adolescents with autism-spectrum disorder26
Digital phenotyping of generalized anxiety disorder: using artificial intelligence to accurately predict symptom severity using wearable sensors in daily life26
Pathological fear, anxiety and negative affect exhibit distinct neurostructural signatures: evidence from psychiatric neuroimaging meta-analysis26
Plasma neurofilament light as a potential biomarker for cognitive decline in a longitudinal study of middle-aged urban adults26
Translational opportunities in animal and human models to study alcohol use disorder26
Transcranial direct current stimulation induces long-term potentiation-like plasticity in the human visual cortex26
CD36 deficiency affects depressive-like behaviors possibly by modifying gut microbiota and the inflammasome pathway in mice26
Combined effects of genotype and childhood adversity shape variability of DNA methylation across age26
Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 193625
Adverse childhood experiences, daytime salivary cortisol, and depressive symptoms in early adulthood: a longitudinal genetically informed twin study25
Chronic mild stress-induced protein dysregulations correlated with susceptibility and resiliency to depression or anxiety revealed by quantitative proteomics of the rat prefrontal cortex25
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