Oncogenesis

Papers
(The TQCC of Oncogenesis is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
MYB oncoproteins: emerging players and potential therapeutic targets in human cancer81
CXCL5 promotes gastric cancer metastasis by inducing epithelial-mesenchymal transition and activating neutrophils70
Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis64
Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle63
Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia60
TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple54
Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation52
Hypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA52
TGF-β1-mediated transition of resident fibroblasts to cancer-associated fibroblasts promotes cancer metastasis in gastrointestinal stromal tumor50
Metformin exhibits antiproliferation activity in breast cancer via miR-483-3p/METTL3/m6A/p21 pathway49
Targeting PD-L1 in non-small cell lung cancer using CAR T cells49
Exploring and modelling colon cancer inter-tumour heterogeneity: opportunities and challenges49
miR-18a promotes glioblastoma development by down-regulating ALOXE3-mediated ferroptotic and anti-migration activities47
ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis44
Lipids in cancer: a global view of the contribution of lipid pathways to metastatic formation and treatment resistance43
Tumor-derived HMGB1 induces CD62Ldim neutrophil polarization and promotes lung metastasis in triple-negative breast cancer42
Suppressing DRP1-mediated mitochondrial fission and mitophagy increases mitochondrial apoptosis of hepatocellular carcinoma cells in the setting of hypoxia42
PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas39
Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors38
COX6B2 drives metabolic reprogramming toward oxidative phosphorylation to promote metastasis in pancreatic ductal cancer cells38
LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival37
lncRNA-SOX2OT promotes hepatocellular carcinoma invasion and metastasis through miR-122-5p-mediated activation of PKM237
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts36
YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells31
Targeting IL-3Rα on tumor-derived endothelial cells blunts metastatic spread of triple-negative breast cancer via extracellular vesicle reprogramming30
Regulation of invasion and peritoneal dissemination of ovarian cancer by mesothelin manipulation30
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis30
Desmoplastic small round cell tumor is dependent on the EWS-WT1 transcription factor30
Diethyldithiocarbamate-copper complex (CuET) inhibits colorectal cancer progression via miR-16-5p and 15b-5p/ALDH1A3/PKM2 axis-mediated aerobic glycolysis pathway29
IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming29
Feedback activation of STAT3 limits the response to PI3K/AKT/mTOR inhibitors in PTEN-deficient cancer cells27
MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription27
Dissecting the single-cell transcriptome network in patients with esophageal squamous cell carcinoma receiving operative paclitaxel plus platinum chemotherapy26
LIMK2 promotes the metastatic progression of triple-negative breast cancer by activating SRPK125
OXER1 and RACK1-associated pathway: a promising drug target for breast cancer progression25
PRMT1 promotes neuroblastoma cell survival through ATF524
Breast cancer in the era of integrating “Omics” approaches24
Tumor-secreted exosomal Wnt2B activates fibroblasts to promote cervical cancer progression24
Angiogenesis and immune checkpoint dual blockade in combination with radiotherapy for treatment of solid cancers: opportunities and challenges24
Epigenetic regulation of TGF-β-induced EMT by JMJD3/KDM6B histone H3K27 demethylase24
Emerging role of SWI/SNF complex deficiency as a target of immune checkpoint blockade in human cancers24
Surface charge of Merkel cell polyomavirus small T antigen determines cell transformation through allosteric FBW7 WD40 domain targeting23
SOX9 interacts with FOXC1 to activate MYC and regulate CDK7 inhibitor sensitivity in triple-negative breast cancer23
microRNA-199a-3p inhibits hepatic apoptosis and hepatocarcinogenesis by targeting PDCD423
Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia23
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis22
MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine22
Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway22
EHF suppresses cancer progression by inhibiting ETS1-mediated ZEB expression22
Tumour heterogeneity and evolutionary dynamics in colorectal cancer21
Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells20
TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition20
Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma20
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer20
Loss of HAT1 expression confers BRAFV600E inhibitor resistance to melanoma cells by activating MAPK signaling via IGF1R19
Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma19
TRPC1 promotes the genesis and progression of colorectal cancer via activating CaM-mediated PI3K/AKT signaling axis19
GLIS2 promotes colorectal cancer through repressing enhancer activation19
USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC319
Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity19
CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment19
Emerging role of G9a in cancer stemness and promises as a therapeutic target18
Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor18
PNO1, which is negatively regulated by miR-340-5p, promotes lung adenocarcinoma progression through Notch signaling pathway18
BRN2 expression increases anoikis resistance in melanoma18
PBK phosphorylates MSL1 to elicit epigenetic modulation of CD276 in nasopharyngeal carcinoma18
RETRACTED ARTICLE: Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress18
PRMT6 activates cyclin D1 expression in conjunction with the transcription factor LEF118
Neutrophils and polymorphonuclear myeloid-derived suppressor cells: an emerging battleground in cancer therapy18
Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)17
Inhibition of Bruton’s tyrosine kinase as a therapeutic strategy for chemoresistant oral squamous cell carcinoma and potential suppression of cancer stemness17
E2F1 and epigenetic modifiers orchestrate breast cancer progression by regulating oxygen-dependent ESRP1 expression17
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