Oncogenesis

Papers
(The TQCC of Oncogenesis is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma143
Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis101
Clathrin adapters AP-1 and GGA2 support expression of epidermal growth factor receptor for cell growth98
CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer44
Retraction Note: Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress42
CCT8 recovers WTp53-suppressed cell cycle evolution and EMT to promote colorectal cancer progression41
A novel uterine leiomyoma subtype exhibits NRF2 activation and mutations in genes associated with neddylation of the Cullin 3-RING E3 ligase40
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c39
NRF2 signaling plays an essential role in cancer progression through the NRF2-GPX2-NOTCH3 axis in head and neck squamous cell carcinoma37
Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species35
COX-2/PGE2 upregulation contributes to the chromosome 17p-deleted lymphoma35
Correction: FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway34
Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma33
Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients27
The metastasis suppressor protein NM23-H1 modulates the PI3K-AKT axis through interaction with the p110α catalytic subunit27
Fibroblasts in metastatic lymph nodes confer cisplatin resistance to ESCC tumor cells via PI1627
Tumor-derived miR-130b-3p induces cancer-associated fibroblast activation by targeting SPIN90 in luminal A breast cancer26
TCF7L1 regulates cytokine response and neuroendocrine differentiation of prostate cancer26
Discovery of neddylation E2s inhibitors with therapeutic activity26
Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy25
Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles24
USP32 facilitates non-small cell lung cancer progression via deubiquitinating BAG3 and activating RAF-MEK-ERK signaling pathway24
Retraction Note: PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas23
EDDM3A drives gastric cancer progression by promoting HIF-1α-dependent aerobic glycolysis22
LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers22
CXCL12/CXCR4 axis supports mitochondrial trafficking in tumor myeloma microenvironment21
PELI1 and EGFR cooperate to promote breast cancer metastasis21
Estradiol-mediated inhibition of DNMT1 decreases p53 expression to induce M2-macrophage polarization in lung cancer progression21
Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model20
Activated platelet-derived exosomal LRG1 promotes multiple myeloma cell growth19
DKK1 as a chemoresistant protein modulates oxaliplatin responses in colorectal cancer19
Emerging role of G9a in cancer stemness and promises as a therapeutic target19
LUBAC promotes angiogenesis and lung tumorigenesis by ubiquitinating and antagonizing autophagic degradation of HIF1α18
Vortioxetine hydrobromide inhibits the growth of gastric cancer cells in vivo and in vitro by targeting JAK2 and SRC18
Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway18
A cyclin D1 intrinsically disordered domain accesses modified histone motifs to govern gene transcription18
Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma18
AIFM2 promotes hepatocellular carcinoma metastasis by enhancing mitochondrial biogenesis through activation of SIRT1/PGC-1α signaling17
High expression of PSMC2 promotes gallbladder cancer through regulation of GNG4 and predicts poor prognosis17
miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma17
Non-genetic stratification reveals epigenetic heterogeneity and identifies vulnerabilities of glycolysis addiction in lung adenocarcinoma subtype17
Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development17
AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer17
Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling16
Cell competition in primary and metastatic colorectal cancer16
Hypoxia promotes an inflammatory phenotype of fibroblasts in pancreatic cancer16
ACTL6A suppresses p21Cip1 tumor suppressor expression to maintain an aggressive mesothelioma cancer cell phenotype15
Correction: Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression15
A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties15
Correction to: Migration and invasion is inhibited by silencing ROR1 and ROR2 in chemoresistant ovarian cancer15
Quercetin induces pannexin 1 expression via an alternative transcript with a translationally active 5′ leader in rhabdomyosarcoma15
Correction: TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple15
Correction: Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells15
Heparanase modulates the prognosis and development of BRAF V600E-mutant colorectal cancer by regulating AKT/p27Kip1/Cyclin E2 pathway14
MYCN induces cell-specific tumorigenic growth in RB1-proficient human retinal organoid and chicken retina models of retinoblastoma14
Phosphorylation of IWS1 by AKT maintains liposarcoma tumor heterogeneity through preservation of cancer stem cell phenotypes and mesenchymal-epithelial plasticity14
RIOK3 sustains colorectal cancer cell survival under glucose deprivation via an HSP90α-dependent pathway13
NOTCH1 signaling promotes protein stability of HER3 through the AKT pathway in squamous cell carcinoma of head and neck13
Correction: Elevated ATGL in colon cancer cells and cancer stem cells promotes metabolic and tumorigenic reprogramming reinforced by obesity13
Targeted metabolomics detects a putatively diagnostic signature in plasma and dried blood spots from head and neck paraganglioma patients13
The branched N-glycan of PD-L1 predicts immunotherapy responses in patients with recurrent/metastatic HNSCC13
Correction: USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c13
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