OOIR: Observatory of International Research

Papers

(The median citation count of Oncogenesis is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c	244
C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis	160
PELI1 and EGFR cooperate to promote breast cancer metastasis	91
Noncanonical PRC1.1 targets BTG2 to retain cyclin gene expression and cell growth in neuroblastoma	84
Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients	74
Vortioxetine hydrobromide inhibits the growth of gastric cancer cells in vivo and in vitro by targeting JAK2 and SRC	73
A HOTAIR-associated super-enhancer orchestrates glioblastoma malignancy via MEST	56
Discovery of neddylation E2s inhibitors with therapeutic activity	55
GPX3 suppresses gallbladder cancer progression by modulating redox balance, glycolysis, and anti-tumor immunity	34
NUCKS1 promotes invasion and metastasis of colorectal cancer by stabilizing HDAC2 and activating AKT	32
P4HB maintains Wnt-dependent stemness in glioblastoma stem cells as a precision therapeutic target and serum marker	25
Targeted metabolomics detects a putatively diagnostic signature in plasma and dried blood spots from head and neck paraganglioma patients	25
Sphingosine 1-phosphate signalling in cancer stem cells	25
Metabolic vulnerabilities in pleural mesothelioma	25
Biological differences underlying sex and gender disparities in bladder cancer: current synopsis and future directions	25
Correction: Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells	24
Spindle function and Wnt pathway inhibition by PBX1 to suppress tumor progression via downregulating DCDC2 in colorectal cancer	23
Ubiquitin-specific protease 11 suppresses cuproptosis in colorectal cancer by regulating the ubiquitination and stability of ISCU	23
Correction: Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation	22
PLEKHA4 is transcriptionally regulated by HOXD9 and regulates glycolytic reprogramming and progression in glioblastoma via activation of the STAT3/SOCS-1 pathway	21
UHRF1 overexpression promotes osteosarcoma metastasis through altered exosome production and AMPK/SEMA3E suppression	20
Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma	19
Exosomes and cancer - Diagnostic and prognostic biomarkers and therapeutic vehicle	19
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein	19
Multi-omics analysis reveals LARP1 as a key integrator of translation and metabolism in AML	19

USP35 promotes cell proliferation and chemotherapeutic resistance through stabilizing FUCA1 in colorectal cancer	18
Involvement of the pro-oncogenic enzyme fatty acid synthase in the hallmarks of cancer: a promising target in anti-cancer therapies	18
Collagen type IV alpha 6 promotes tumor progression and chemoresistance in ovarian cancer by activating the discoidin domain receptor 1 pathway	17
Diltiazem inhibits breast cancer metastasis via mediating growth differentiation factor 15 and epithelial-mesenchymal transition	17
Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma	17
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma	17
STAG2 expression imparts distinct therapeutic vulnerabilities in muscle-invasive bladder cancer cells	17
Preneoplastic cells switch to Warburg metabolism from their inception exposing multiple vulnerabilities for targeted elimination	16
NAC1 transcriptional activation of LDHA induces hepatitis B virus immune evasion leading to cirrhosis and hepatocellular carcinoma development	16
An E3 ligase TRIM1 promotes colorectal cancer progression via K63-linked ubiquitination and activation of HIF1α	16
NFATc1-mediated activation of the pentose phosphate pathway and cell cycle dysregulation collectively drive tumor progression	16
FLT4 activation promotes acute lymphoid leukemia survival through stabilization of MDM2/MDMX and inactivation of p53	16
Transgelin promotes lung cancer progression via activation of cancer-associated fibroblasts with enhanced IL-6 release	15
Anti-PD-1 therapy achieves favorable outcomes in HBV-positive non-liver cancer	15
SLC26A3/NHERF2-IκB/NFκB/p65 feedback loop suppresses tumorigenesis and metastasis in colorectal cancer	15
Involvement of Kindlin-1 in cutaneous squamous cell carcinoma	15
Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation	15
Comprehensive multi-omics analysis of breast cancer reveals distinct long-term prognostic subtypes	15
WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines	15
TGF-β signaling redirects Sox11 gene regulatory activity to promote partial EMT and collective invasion of oncogenically transformed intestinal organoids	14
Targeting macrophage migration inhibitory factor as a potential therapeutic strategy in colorectal cancer	14
Generating in vitro models of NTRK-fusion mesenchymal neoplasia as tools for investigating kinase oncogenic activation and response to targeted therapy	14
WDR4 promotes the progression and lymphatic metastasis of bladder cancer via transcriptional down-regulation of ARRB2	14
HLTF promotes hepatocellular carcinoma progression by enhancing SRSF1 stability and activating ERK/MAPK pathway	14
LUBAC promotes angiogenesis and lung tumorigenesis by ubiquitinating and antagonizing autophagic degradation of HIF1α	13
ACT001 inhibited CD133 transcription by targeting and inducing Olig2 ubiquitination degradation	13
Correction: TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple	13
Aberrant APOBEC3C expression induces characteristic genomic instability in pancreatic ductal adenocarcinoma	13
The role of histone demethylase PHF2 as a tumour suppressor in hepatocellular carcinoma by regulating SRXN1	13
Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy	13
Correction: PBK phosphorylates MSL1 to elicit epigenetic modulation of CD276 in nasopharyngeal carcinoma	12
CD147-high extracellular vesicles promote gastric cancer metastasis via VEGF/AKT/eNOS and AKT/mTOR pathways	12
Correction: Targeting IL-3Rα on tumor-derived endothelial cells blunts metastatic spread of triple-negative breast cancer via extracellular vesicle reprogramming	12
Correction: Oncogenic PI3K/AKT promotes the step-wise evolution of combination BRAF/MEK inhibitor resistance in melanoma	12
A dominant SRCAP truncating mutation promotes squamous cell carcinoma progression	11
Retraction Note: A natural food sweetener with anti-pancreatic cancer properties	11
Progesterone receptor potentiates macropinocytosis through CDC42 in pancreatic ductal adenocarcinoma	11
CD9, a tetraspanin in cancer: biology and therapeutic promise in acute leukemia	11
Identification of pancreatic cancer-specific protease substrates for protease-dependent targeted delivery	11
The impact of neoadjuvant chemotherapy on the tumor microenvironment in advanced high-grade serous carcinoma	11
Condensate remodeling reorganizes innate SS18 in synovial sarcomagenesis	10
The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells	10
Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies	10
TFCP2L1 drives stemness and enhances their resistance to Sorafenib treatment by modulating the NANOG/STAT3 pathway in hepatocellular carcinoma	10
Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL	10
The p52-ZER6/G6PD axis alters aerobic glycolysis and promotes tumor progression by activating the pentose phosphate pathway	10
IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis	10
Proteomic meta-analysis unveils new frontiers for biomarkers research in pancreatic carcinoma	10
Transcriptomic analysis identifies B-lymphocyte kinase as a therapeutic target for desmoplastic small round cell tumor cancer stem cell-like cells	9
Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination	9

Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels	9
Dual role of ANGPTL8 in promoting tumor cell proliferation and immune escape during hepatocarcinogenesis	9
Fatty acid uptake mediated by FABP4 promotes the formation of CD8+T cell senescence through lipid peroxidation in the adipocyte-rich microenvironment of Ovarian Cancer	9
Methylation of HBP1 by PRMT1 promotes tumor progression by regulating actin cytoskeleton remodeling	9
Rab37-mediated OPN secretion enriches SPP1+ macrophages through autocrine–paracrine signaling to drive lung tumor progression	8
Correction: USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c	8
Retraction Note: Platelet-derived growth factor receptor-α and -β promote cancer stem cell phenotypes in sarcomas	8
CENPF (+) cancer cells promote malignant progression of early-stage TP53 mutant lung adenocarcinoma	8
Acidovorax temperans skews neutrophil maturation and polarizes Th17 cells to promote lung adenocarcinoma development	8
Chasing non-existent “microRNAs” in cancer	8
Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model	8
miR-137–LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma	8
CDK4/6 inhibitors and the pRB-E2F1 axis suppress PVR and PD-L1 expression in triple-negative breast cancer	8
Correction: FAM83B inhibits ovarian cancer cisplatin resistance through inhibiting Wnt pathway	8
Lipids in cancer: a global view of the contribution of lipid pathways to metastatic formation and treatment resistance	8
LIN28B inhibition sensitizes cells to p53-restoring PPI therapy through unleashed translational suppression	7
Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling	7
Investigation of lncRNA expression in newly diagnosed multiple myeloma reveals a LINC01432-CELF2 axis as an inhibitor of apoptosis	7
Heparanase modulates the prognosis and development of BRAF V600E-mutant colorectal cancer by regulating AKT/p27Kip1/Cyclin E2 pathway	7
Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2	7
Heterozygotic Brca1 mutation initiates mouse genome instability at embryonic stage	7
RIOK3 sustains colorectal cancer cell survival under glucose deprivation via an HSP90α-dependent pathway	7
MYCN induces cell-specific tumorigenic growth in RB1-proficient human retinal organoid and chicken retina models of retinoblastoma	7
Correction: FIBP knockdown attenuates growth and enhances chemotherapy in colorectal cancer via regulating GSK3β-related pathways	7
LPA receptor 1 (LPAR1) is a novel interaction partner of Filamin A that promotes Filamin A phosphorylation, MRTF-A transcriptional activity and oncogene-induced senescence	6
Programmed cell death 11 modulates but not entirely relies on p53-HDM2 loop to facilitate G2/M transition in colorectal cancer cells	6
DDX3X interacts with SIRT7 to promote PD-L1 expression to facilitate PDAC progression	6
Inhibition of LDHB triggers DNA damage and increases cisplatin sensitivity in pleural mesothelioma	6
Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy	6
ONC201 enhances the cytotoxic effect of cisplatin through ATF3/ATF4/CHOP in head and neck squamous cell carcinoma cells	6
A MYC-ZNF148-ID1/3 regulatory axis modulating cancer stem cell traits in aggressive breast cancer	6
ACSL6 modulates docosahexaenoic acid-induced cytotoxicity to potentiate chemotherapy response in colorectal and breast cancer	6
Targeting pregnane X receptor with a potent agonist-based PROTAC to delay colon cancer relapse	6
Deep learning identifies a T-cell exhaustion-dependent transcriptional signature for predicting clinical outcomes and response to immune checkpoint blockade	6
SHP1 expression in tumor-associated dendritic cells drives immunoevasion via impairing CD8+ memory T cell responses	6
Myeloma mesenchymal stem cells’ bioenergetics afford a novel selective therapeutic target	5
Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer	5
Correction: LXRα limits TGFβ-dependent hepatocellular carcinoma associated fibroblast differentiation	5
USP21-mediated G3BP1 stabilization accelerates proliferation and metastasis of esophageal squamous cell carcinoma via activating Wnt/β-Catenin signaling	5
Stabilization of FASN by USP5-mediated deubiquitination promotes hepatocellular carcinoma progression	5
The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells	5
Retraction Note: Acetyl-CoA synthetase 3 promotes bladder cancer cell growth under metabolic stress	5
Metastasis suppressing properties of the cell-surface anchored serine protease prostasin: new functional and mechanistic insights from breast cancer	5
Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12	5
Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation	5
SLC6A19-mediated tryptophan uptake suppresses renal cell carcinoma metastasis via activating NAD+-dependent deacetylase SIRT1	5