OOIR: Observatory of International Research

Papers

(The TQCC of Nature Biomedical Engineering is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)

Article	Citations
Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow	417
First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows	398
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip	373
Soft and elastic hydrogel-based microelectronics for localized low-voltage neuromodulation	351
Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor	312
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy	289
Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation	275
Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip	274
Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning	266
The evolution of commercial drug delivery technologies	220
Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers	218
Rapidly separable microneedle patch for the sustained release of a contraceptive	215
Opportunities and challenges of translational 3D bioprinting	202
Large-area MRI-compatible epidermal electronic interfaces for prosthetic control and cognitive monitoring	177
Manufacturing of primed mesenchymal stromal cells for therapy	167
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours	162
Mechano-acoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch	157
Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy	139
Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors	132
Functionalized helical fibre bundles of carbon nanotubes as electrochemical sensors for long-term in vivo monitoring of multiple disease biomarkers	130
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability	128
A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons	123
Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain	119
Computationally guided personalized targeted ablation of persistent atrial fibrillation	118
Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier	114
The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency	112
Optoacoustic mesoscopy for biomedicine	106
Patient-specific reconstruction of volumetric computed tomography images from a single projection view via deep learning	106
A viscoelastic adhesive epicardial patch for treating myocardial infarction	104
Adenine base editing in an adult mouse model of tyrosinaemia	100
Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model	99
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium	92
Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility	90
Exploration of the nanomedicine-design space with high-throughput screening and machine learning	87
Engineering patient-specific cancer immunotherapies	87
Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging	85
Detection of anaemia from retinal fundus images via deep learning	82
Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function	77
Spectral tracing of deuterium for imaging glucose metabolism	76
Real-time analysis of the behaviour of groups of mice via a depth-sensing camera and machine learning	75
Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity	71
Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade	70
Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue	65
A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens	62
Wireless optofluidic brain probes for chronic neuropharmacology and photostimulation	62