Nature Biomedical Engineering

(The TQCC of Nature Biomedical Engineering is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow417
First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows398
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip373
Soft and elastic hydrogel-based microelectronics for localized low-voltage neuromodulation351
Detection of unamplified target genes via CRISPR–Cas9 immobilized on a graphene field-effect transistor312
A bioprinted human-glioblastoma-on-a-chip for the identification of patient-specific responses to chemoradiotherapy289
Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation275
Ultrasensitive detection of circulating exosomes with a 3D-nanopatterned microfluidic chip274
Virtual histological staining of unlabelled tissue-autofluorescence images via deep learning266
The evolution of commercial drug delivery technologies220
Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers218
Rapidly separable microneedle patch for the sustained release of a contraceptive215
Opportunities and challenges of translational 3D bioprinting202
Large-area MRI-compatible epidermal electronic interfaces for prosthetic control and cognitive monitoring177
Manufacturing of primed mesenchymal stromal cells for therapy167
Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumours162
Mechano-acoustic sensing of physiological processes and body motions via a soft wireless device placed at the suprasternal notch157
Phage-guided modulation of the gut microbiota of mouse models of colorectal cancer augments their responses to chemotherapy139
Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors132
Functionalized helical fibre bundles of carbon nanotubes as electrochemical sensors for long-term in vivo monitoring of multiple disease biomarkers130
Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability128
A nanoelectrode array for obtaining intracellular recordings from thousands of connected neurons123
Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain119
Computationally guided personalized targeted ablation of persistent atrial fibrillation118
Use of a supramolecular polymeric hydrogel as an effective post-operative pericardial adhesion barrier114
The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency112
Optoacoustic mesoscopy for biomedicine106
Patient-specific reconstruction of volumetric computed tomography images from a single projection view via deep learning106
A viscoelastic adhesive epicardial patch for treating myocardial infarction104
Adenine base editing in an adult mouse model of tyrosinaemia100
Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model99
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium92
Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility90
Exploration of the nanomedicine-design space with high-throughput screening and machine learning87
Engineering patient-specific cancer immunotherapies87
Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging85
Detection of anaemia from retinal fundus images via deep learning82
Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function77
Spectral tracing of deuterium for imaging glucose metabolism76
Real-time analysis of the behaviour of groups of mice via a depth-sensing camera and machine learning75
Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity71
Retinal-detachment repair and vitreous-like-body reformation via a thermogelling polymer endotamponade70
Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue65
A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens62
Wireless optofluidic brain probes for chronic neuropharmacology and photostimulation62