Cold Spring Harbor Perspectives in Medicine

Papers
(The TQCC of Cold Spring Harbor Perspectives in Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Developmental Oncology: Principles and Therapy of Cancers of Children and Young Adults403
Tuberculosis Drug Discovery in the Age of Artificial Intelligence167
iPSC-RPE in Retinal Degeneration: Recent Advancements and Future Perspectives94
Pathomechanisms of Inherited Retinal Degeneration and Perspectives for Neuroprotection46
Personalized Financial Planning Using Applied Genetics42
Monitoring the Cell Cycle of Tumor Cells in Mouse Models of Human Cancer42
Developing New Vectors for Retinal Gene Therapy36
Pediatric Tuberculosis: Epidemiology, Disease Spectrum, Diagnosis, and Management32
Toward Retinal Organoids in High-Throughput31
Metabolic Signaling in Cancer29
Ovarian Clear Cell Carcinoma: An Endometriosis-Associated Cancer with Therapeutic Challenges29
Embryological Insights into the Origin of Epithelial Cancers of the Female Reproductive Tract27
How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research24
Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes21
α-Synuclein in Parkinson's Disease: 12 Years Later20
Genetics and Epigenetics of Type 1 Diabetes Self-Reactive T Cells19
Clinical Immunologic Interventions for the Treatment of Type 1 Diabetes: Challenges, Choice, and Timing of Immunomodulators18
From the Inside Out: Exposing the Roles of Urea Cycle Enzymes in Tumors and Their Micro and Macro Environments18
Mechanisms of Organ-Specific Metastasis of Breast Cancer18
Optogenetic Vision Restoration17
Therapeutic Gene Editing in Inherited Retinal Disorders16
Autophagy and Protein Quality Control in Parkinson's Disease16
Retinal Disorders16
Aging and Inflammation16
Functional Neuroanatomy of the Normal and Pathological Basal Ganglia16
Endothelial Cell Differentiation and Hemogenic Specification15
Who Are the Space Invaders? Planetary Protection and the Role of Biological Interactions between Extraterrestrial and Terrestrial Biospheres14
Immunology of Retinitis Pigmentosa and Gene Therapy–Associated Uveitis14
Lipid Alterations and Pathogenic Roles in Synucleinopathies13
Innate Immunity in Type 1 Diabetes13
The Pathogenesis of Type 1 Diabetes13
Epitope Hierarchy in Type 1 Diabetes Pathogenesis13
From Life Span to Health Span: Declaring “Victory” in the Pursuit of Human Longevity12
Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities12
Evolutionary Approaches in Aging Research12
The Funding Channels of Geroscience11
Models of High-Grade Serous Ovarian Carcinoma11
Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl11
Toward a Unified Theory of Why Young People Develop Cancer10
Breast Cancer Immunity: It is TIME for the Next Chapter10
The Human Pancreas in Type 1 Diabetes: Lessons Learned from the Network of Pancreatic Organ Donors with Diabetes10
Germline Genetic Testing for Hereditary Breast and Ovarian Cancer: Current Concepts in Risk Evaluation10
Modeling Brain Vasculature Immune Interactions In Vitro10
Lymphatic Tissue and Organ Engineering for In Vitro Modeling and In Vivo Regeneration10
Early Detection of Ovarian Cancer10
Wnt/frizzled Signaling in Endothelium: A Major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity10
Beyond Static Pipes: Mechanisms and In Vitro Models of Vascular Aging10
Dormancy in Breast Cancer9
T Cell Differentiation in Autoimmune Type 1 Diabetes9
New Paradigms in the Clinical Management of Li–Fraumeni Syndrome9
Notch Signaling in Vascular Endothelial and Mural Cell Communications9
A History of Biosafety: U.S. Perspective9
Comparison of Worldwide Disease Prevalence and Genetic Prevalence of Inherited Retinal Diseases and Variant Interpretation Considerations9
Leucine-Rich Repeat Kinase 2: Pathways to Parkinson's Disease9
The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer9
Endothelial Lipid Metabolism9
Understanding the Warburg Effect in Cancer9
Retinal Degeneration Animal Models in Bardet–Biedl Syndrome and Related Ciliopathies9
Emerging Therapies for Breast Cancer8
Parallels in Canonical Developmental Signaling Pathways between Normal Development and the Tumor Microenvironment8
History of Finding Genes and Mutations Causing Inherited Retinal Diseases8
Technologies for Decoding Cancer Metabolism with Spatial Resolution8
Cellular Origins and Lineage Plasticity in Cancer8
Historical Perspectives of Parkinson's Disease: Early Clinical Descriptions and Neurological Therapies8
Mechanics of Lymphatic Pumping and Lymphatic Function8
Osteosarcoma through the Lens of Bone Development, Signaling, and Microenvironment8
Next-Generation Modeling of Cancer Using Organoids8
The Extraordinary Phenotypic and Genetic Variability of Retinal and Macular Degenerations: The Relevance to Therapeutic Developments8
Safety and Security in the Lithotroph of Microbiology—A Commentary8
Rare Epithelial Ovarian Cancers: Low Grade Serous and Mucinous Carcinomas8
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