Cold Spring Harbor Perspectives in Medicine

Papers
(The TQCC of Cold Spring Harbor Perspectives in Medicine is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Developmental Oncology: Principles and Therapy of Cancers of Children and Young Adults388
iPSC-RPE in Retinal Degeneration: Recent Advancements and Future Perspectives166
Pathomechanisms of Inherited Retinal Degeneration and Perspectives for Neuroprotection88
Personalized Financial Planning Using Applied Genetics45
Monitoring the Cell Cycle of Tumor Cells in Mouse Models of Human Cancer39
Developing New Vectors for Retinal Gene Therapy38
Metabolic Signaling in Cancer36
Toward Retinal Organoids in High-Throughput32
Ovarian Clear Cell Carcinoma: An Endometriosis-Associated Cancer with Therapeutic Challenges31
How CRISPR Is Revolutionizing the Generation of New Models for Cancer Research27
Embryological Insights into the Origin of Epithelial Cancers of the Female Reproductive Tract27
Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes26
Clinical Immunologic Interventions for the Treatment of Type 1 Diabetes: Challenges, Choice, and Timing of Immunomodulators24
α-Synuclein in Parkinson's Disease: 12 Years Later24
Genetics and Epigenetics of Type 1 Diabetes Self-Reactive T Cells21
Mechanisms of Organ-Specific Metastasis of Breast Cancer20
From the Inside Out: Exposing the Roles of Urea Cycle Enzymes in Tumors and Their Micro and Macro Environments18
Optogenetic Vision Restoration17
Therapeutic Gene Editing in Inherited Retinal Disorders17
Aging and Inflammation16
Retinal Disorders16
Functional Neuroanatomy of the Normal and Pathological Basal Ganglia16
Endothelial Cell Differentiation and Hemogenic Specification15
Autophagy and Protein Quality Control in Parkinson's Disease15
Epitope Hierarchy in Type 1 Diabetes Pathogenesis13
Innate Immunity in Type 1 Diabetes13
Who Are the Space Invaders? Planetary Protection and the Role of Biological Interactions between Extraterrestrial and Terrestrial Biospheres13
Immunology of Retinitis Pigmentosa and Gene Therapy–Associated Uveitis13
Lipid Alterations and Pathogenic Roles in Synucleinopathies12
The Pathogenesis of Type 1 Diabetes12
The Funding Channels of Geroscience12
Breast Cancer Immunity: It is TIME for the Next Chapter11
Models of High-Grade Serous Ovarian Carcinoma11
From Life Span to Health Span: Declaring “Victory” in the Pursuit of Human Longevity11
Early Detection of Ovarian Cancer11
Lessons Learned from the Development of the First FDA-Approved Gene Therapy Drug, Voretigene Neparvovec-rzyl10
Beyond Static Pipes: Mechanisms and In Vitro Models of Vascular Aging10
Lymphatic Tissue and Organ Engineering for In Vitro Modeling and In Vivo Regeneration10
Acute Promyelocytic Leukemia, Retinoic Acid, and Arsenic: A Tale of Dualities10
The Human Pancreas in Type 1 Diabetes: Lessons Learned from the Network of Pancreatic Organ Donors with Diabetes10
A History of Biosafety: U.S. Perspective10
Evolutionary Approaches in Aging Research10
Toward a Unified Theory of Why Young People Develop Cancer10
Germline Genetic Testing for Hereditary Breast and Ovarian Cancer: Current Concepts in Risk Evaluation10
T Cell Differentiation in Autoimmune Type 1 Diabetes9
Dormancy in Breast Cancer9
Wnt/frizzled Signaling in Endothelium: A Major Player in Blood-Retinal- and Blood-Brain-Barrier Integrity9
Understanding the Warburg Effect in Cancer9
Endothelial Lipid Metabolism9
Modeling Brain Vasculature Immune Interactions In Vitro9
Comparison of Worldwide Disease Prevalence and Genetic Prevalence of Inherited Retinal Diseases and Variant Interpretation Considerations9
New Paradigms in the Clinical Management of Li–Fraumeni Syndrome8
Leucine-Rich Repeat Kinase 2: Pathways to Parkinson's Disease8
Rare Epithelial Ovarian Cancers: Low Grade Serous and Mucinous Carcinomas8
Parallels in Canonical Developmental Signaling Pathways between Normal Development and the Tumor Microenvironment8
Emerging Therapies for Breast Cancer8
Notch Signaling in Vascular Endothelial and Mural Cell Communications8
The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer8
The Extraordinary Phenotypic and Genetic Variability of Retinal and Macular Degenerations: The Relevance to Therapeutic Developments8
Next-Generation Modeling of Cancer Using Organoids8
Retinal Degeneration Animal Models in Bardet–Biedl Syndrome and Related Ciliopathies8
Cellular Origins and Lineage Plasticity in Cancer8
Technologies for Decoding Cancer Metabolism with Spatial Resolution8
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