OOIR: Observatory of International Research

Papers

(The median citation count of ACS Combinatorial Science is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)

Article	Citations
Targeting the Dimerization of the Main Protease of Coronaviruses: A Potential Broad-Spectrum Therapeutic Strategy	234
Progress in Natural Compounds/siRNA Co-delivery Employing Nanovehicles for Cancer Therapy	64
Cyclic Imines in Ugi and Ugi-Type Reactions	52
Dielectrophoretic Manipulation of Cancer Cells and Their Electrical Characterization	36
A High-Throughput Structural and Electrochemical Study of Metallic Glass Formation in Ni–Ti–Al	31
Profiling SARS-CoV-2 Main Protease (M^PRO) Binding to Repurposed Drugs Using Molecular Dynamics Simulations in Classical and Neural Network-Trained Force Fields	28
High Entropy and Sluggish Diffusion “Core” Effects in Senary FCC Al–Co–Cr–Fe–Ni–Mn Alloys	28
High-Throughput Experimentation and Continuous Flow Evaluation of Nucleophilic Aromatic Substitution Reactions	28
MoS₂–Calix[4]arene Catalyzed Synthesis and Molecular Docking Study of 2,4,5-Trisubstituted Imidazoles As Potent Inhibitors of Mycobacterium tuberculosis	26
Cautionary Guidelines for Machine Learning Studies with Combinatorial Datasets	24
Ce(OTf)₃-Catalyzed Multicomponent Reaction of Alkynyl Carboxylic Acids, tert-Butyl Isocyanide, and Azides for the Assembly of Triazole–Oxazole Derivatives	24
Development of High-Throughput Methods for Sodium-Ion Battery Cathodes	21
Denoising DNA Encoded Library Screens with Sparse Learning	20
Development of an Aptamer-Based Lateral Flow Assay for the Detection of C-Reactive Protein Using Microarray Technology as a Prescreening Platform	19
Expanding the Chemical Diversity of Genetically Encoded Libraries	19
Exploring the First High-Entropy Thin Film Libraries: Composition Spread-Controlled Crystalline Structure	19
Sorting Technology for Circulating Tumor Cells Based on Microfluidics	18
Prospects and Therapeutic Applications of Cardiac Glycosides in Cancer Remediation	18
Fe₃O₄@GlcA@Cu-MOF: A Magnetic Metal–Organic Framework as a Recoverable Catalyst for the Hydration of Nitriles and Reduction of Isothiocyanates, Isocyanates, and Isocyanides	16
One Reacts as Two: Applications of N-Isocyaniminotriphenylphosphorane in Diversity-Oriented Synthesis	15
Facile Synthesis of Novel Hexahydroimidazo[1,2-a]pyridine Derivatives by One-Pot, Multicomponent Reaction under Ambient Conditions	15
Isolation of Chemically Cyclized Peptide Binders Using Yeast Surface Display	15
Efficient Machine-Learning-Aided Screening of Hydrogen Adsorption on Bimetallic Nanoclusters	15
High-Throughput Exploration of Metal Vanadate Thin-Film Systems (M–V–O, M = Cu, Ag, W, Cr, Co, Fe) for Solar Water Splitting: Composition, Structure, Stability, and Photoelectrochemical Properties	14
Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls	14

Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors	14
Activity Prediction of Small Molecule Inhibitors for Antirheumatoid Arthritis Targets Based on Artificial Intelligence	13
An Aptamer Linked Immobilized Sorbent Assay (ALISA) to Detect Circulatory IFN-α, an Inflammatory Protein among Tuberculosis Patients	13
Direct, Competitive Comparison of Linear, Monocyclic, and Bicyclic Libraries Using mRNA Display	12
Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines	12
Efficient Arylation of 2,7-Naphthyridin-1(2H)-one with Diaryliodonium Salts and Discovery of a New Selective MET/AXL Kinase Inhibitor	11
Optimized Multimetal Sensitized Phosphor for Enhanced Red Up-Conversion Luminescence by Machine Learning	11
Diversity-Oriented Synthesis of Thiazolidine-2-imines via Microwave-Assisted One-Pot, Telescopic Approach and Its Interaction with Biomacromolecules	10
Combinatorial Exploration and Mapping of Phase Transformation in a Ni–Ti–Co Thin Film Library	10
Valence Band Modification of a (Ga_xIn_1–x)₂O₃ Solid Solution System Fabricated by Combinatorial Synthesis	10
Synthesis of Bioactive Complex Small Molecule–Ciprofloxacin Conjugates and Evaluation of Their Antibacterial Activity	10
High-Throughput and Autonomous Grazing Incidence X-ray Diffraction Mapping of Organic Combinatorial Thin-Film Library Driven by Machine Learning	9
Fast-Track to Research Data Management in Experimental Material Science–Setting the Ground for Research Group Level Materials Digitalization	9
High-Throughput Characterization of (Fe_xCo_1–x)₃O₄ Thin-Film Composition Spreads	9
Aldol Reactions of Biorenewable Triacetic Acid Lactone Precursor Evaluated Using Desorption Electrospray Ionization Mass Spectrometry High-Throughput Experimentation and Validated by Continuous Flow S	9
Comprehensive Prediction of Molecular Recognition in a Combinatorial Chemical Space Using Machine Learning	9
Identifying Optimal Strain in Bismuth Telluride Thermoelectric Film by Combinatorial Gradient Thermal Annealing and Machine Learning	8
Ni-Nitrilotriacetic Acid Affinity SELEX Method for Selection of DNA Aptamers Specific to the N-Cadherin Protein	8
Rapid Assembly and Screening of Multivalent Immune Cell-Redirecting Therapies for Leukemia	8
High Throughput Synthesis and Screening of Oxygen Reduction Catalysts in the MTiO₃ (M = Ca, Sr, Ba) Perovskite Phase Diagram	7
Magnetic Bead-Immobilized Mammalian Cells Are Effective Targets to Enrich Ligand-Displaying Yeast	7
Scaffolding-Induced Property Modulation of Chemical Space	7
Development of Mischmetal–Fe–Co–B Permanent Magnet Alloys via High-Throughput Methods	7
Use of Target-Displaying Magnetized Yeast in Screening mRNA-Display Peptide Libraries to Identify Ligands	7
Detection of Thiol Functionality and Disulfide Bond Formation by Polyoxometalate	7
Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization	7