Biomedical Optics Express

Article	Citations
Label-free plasmonic immunosensor for cortisol detection in a D-shaped optical fiber	92
Technical considerations in the Verasonics research ultrasound platform for developing a photoacoustic imaging system	60
High-speed adaptive optics line-scan OCT for cellular-resolution optoretinography	52
HER2 biosensing through SPR-envelope tracking in plasmonic optical fiber gratings	52
Multi-scale GCN-assisted two-stage network for joint segmentation of retinal layers and discs in peripapillary OCT images	51
Optical coherence tomography-based tissue dynamics imaging for longitudinal and drug response evaluation of tumor spheroids	50
ML-SIM: universal reconstruction of structured illumination microscopy images using transfer learning	50
High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source	49
Machine learning-based LIBS spectrum analysis of human blood plasma allows ovarian cancer diagnosis	48
End-to-end Res-Unet based reconstruction algorithm for photoacoustic imaging	47
Quasi-distributed fiber optic sensor-based control system for interstitial laser ablation of tissue: theoretical and experimental investigations	45
Gold nanoparticle enhanced detection of EGFR with a terahertz metamaterial biosensor	44
Convolutional neural network for resolution enhancement and noise reduction in acoustic resolution photoacoustic microscopy	44
Terahertz dielectric spectroscopy of human brain gliomas and intact tissues ex vivo: double-Debye and double-overdamped-oscillator models of dielectric response	43
AV-Net: deep learning for fully automated artery-vein classification in optical coherence tomography angiography	43
Respiratory and heart rate monitoring using an FBG 3D-printed wearable system	42
Comparative study of the influence of imaging resolution on linear retardance parameters derived from the Mueller matrix	42
Smartphone-based optical spectroscopic platforms for biomedical applications: a review [Invited]	41
Photoacoustic computed tomography for functional human brain imaging [Invited]	41
Choosing a model for laser speckle contrast imaging	41
Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device	40
Photoacoustic-guided surgery from head to toe [Invited]	38
Impact of skin tone on photoacoustic oximetry and tools to minimize bias	37
Multi-resolution open-top light-sheet microscopy to enable efficient 3D pathology workflows	37
Hybrid mesh and voxel based Monte Carlo algorithm for accurate and efficient photon transport modeling in complex bio-tissues	36

Optical ptychography for biomedical imaging: recent progress and future directions [Invited]	35
Real-time, wide-field and high-quality single snapshot imaging of optical properties with profile correction using deep learning	34
Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy	34
Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation	33
Towards in-vivo label-free detection of brain tumor margins with epi-illumination tomographic quantitative phase imaging	33
Imaging of vitreous cortex hyalocyte dynamics using non-confocal quadrant-detection adaptive optics scanning light ophthalmoscopy in human subjects	33
Dual-view oblique plane microscopy (dOPM)	32
Integrating adaptive optics-SLO and OCT for multimodal visualization of the human retinal pigment epithelial mosaic	32
Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities	32
Acoustic impact of the human skull on transcranial photoacoustic imaging	32
Hybrid deep learning network for vascular segmentation in photoacoustic imaging	31
High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging	31
Wearable and wireless time-domain near-infrared spectroscopy system for brain and muscle hemodynamic monitoring	31
Rapid and label-free urine test based on surface-enhanced Raman spectroscopy for the non-invasive detection of colorectal cancer at different stages	31
Real-time noise reduction based on ground truth free deep learning for optical coherence tomography	30
Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems	30
Hyperspectral imaging and robust statistics in non-melanoma skin cancer analysis	30
Polarization and depolarization metrics as optical markers in support to histopathology of ex vivo colon tissue	30
Automatic classification of esophageal disease in gastroscopic images using an efficient channel attention deep dense convolutional neural network	29
Wearable device for remote monitoring of transcutaneous tissue oxygenation	29
Ballistocardiography monitoring system based on optical fiber interferometer aided with heartbeat segmentation algorithm	29
Monte Carlo analysis of optical heart rate sensors in commercial wearables: the effect of skin tone and obesity on the photoplethysmography (PPG) signal	28
Applications of augmented reality in ophthalmology [Invited]	28
Optical monitoring of cerebral perfusion and metabolism in adults during cardiac surgery with cardiopulmonary bypass	28
Functional optical coherence tomography enables in vivo optoretinography of photoreceptor dysfunction due to retinal degeneration	28
Bayesian deep learning for reliable oral cancer image classification	27
Differentiation of burn wounds in an in vivo porcine model using terahertz spectroscopy	27
Skull acoustic aberration correction in photoacoustic microscopy using a vector space similarity model: a proof-of-concept simulation study	27
Auto-detection of cervical collagen and elastin in Mueller matrix polarimetry microscopic images using K-NN and semantic segmentation classification	26
Fast in vivo multiphoton light-sheet microscopy with optimal pulse frequency	26
Vision-correcting holographic display: evaluation of aberration correcting hologram	26
Deep learning approach to improve tangential resolution in photoacoustic tomography	26
Computational tissue staining of non-linear multimodal imaging using supervised and unsupervised deep learning	26
Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes	26
Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography	26
Terahertz dielectric spectroscopy and solid immersion microscopy of ex vivo glioma model 101.8: brain tissue heterogeneity	25
Evolution of adaptive optics retinal imaging [Invited]	25
Probing variations of fibrous structures during the development of breast ductal carcinoma tissues via Mueller matrix imaging	25
Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies	25
Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging	25
Portable ultra-widefield fundus camera for multispectral imaging of the retina and choroid	25
Deep-learning based multi-modal retinal image registration for the longitudinal analysis of patients with age-related macular degeneration	25
Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy	25
Single-shot hybrid photoacoustic-fluorescent microendoscopy through a multimode fiber with wavefront shaping	25
Strip-based digital image registration for distortion minimization and robust eye motion measurement from scanned ophthalmic imaging systems	24
Dual GRIN lens two-photon endoscopy for high-speed volumetric and deep brain imaging	24
Transcranial photobiomodulation-induced changes in human brain functional connectivity and network metrics mapped by whole-head functional near-infrared spectroscopy in vivo	24
Detection of cerebral tauopathy in P301L mice using high-resolution large-field multifocal illumination fluorescence microscopy	24
Model of dynamic speckle evolution for evaluating laser speckle contrast measurements of tissue dynamics	24
Deep-learning super-resolution light-sheet add-on microscopy (Deep-SLAM) for easy isotropic volumetric imaging of large biological specimens	24

Transfontanelle photoacoustic imaging: ultrasound transducer selection analysis	24
Deep learning-based light scattering microfluidic cytometry for label-free acute lymphocytic leukemia classification	24
Signal quality index: an algorithm for quantitative assessment of functional near infrared spectroscopy signal quality	23
Wavelength and pulse energy optimization for detecting hypoxia in photoacoustic imaging of the neonatal brain: a simulation study	23
Optimizing deep bone ablation by means of a microsecond Er:YAG laser and a novel water microjet irrigation system	23
Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited]	23
Weakly supervised anomaly segmentation in retinal OCT images using an adversarial learning approach	23
Fluorescence intensity and lifetime redox ratios detect metabolic perturbations in T cells	23
Multi-spectral intravascular photoacoustic/ultrasound/optical coherence tomography tri-modality system with a fully-integrated 0.9-mm full field-of-view catheter for plaque vulnerability imaging	23
Towards label-free 3D segmentation of optical coherence tomography images of the optic nerve head using deep learning	23
Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy	23
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast	23
Quantitative structural imaging of keratoconic corneas using polarization-resolved SHG microscopy	22
Holo-UNet: hologram-to-hologram neural network restoration for high fidelity low light quantitative phase imaging of live cells	22
Sustained fatigue assessment during isometric exercises with time-domain near infrared spectroscopy and surface electromyography signals	22
Effects of high intensity non-ionizing terahertz radiation on human skin fibroblasts	22
Resolution enhancement and realistic speckle recovery with generative adversarial modeling of micro-optical coherence tomography	22
Robust non-contact peripheral oxygenation saturation measurement using smartphone-enabled imaging photoplethysmography	22
Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy	22
Optical property recovery with spatially-resolved diffuse reflectance at short source-detector separations using a compact fiber-optic probe	21
Miniature structured illumination microscope for in vivo 3D imaging of brain structures with optical sectioning	21
Adaptive optics for optical microscopy [Invited]	21
High compression deep learning based single-pixel hyperspectral macroscopic fluorescence lifetime imaging in vivo	21
Non-contact terahertz spectroscopic measurement of the intraocular pressure through corneal hydration mapping	21
Optical design and performance of a trifocal sinusoidal diffractive intraocular lens	21
Quantitative Jones matrix imaging using vectorial Fourier ptychography	21
Evaluation of the robustness of cerebral oximetry to variations in skin pigmentation using a tissue-simulating phantom	21
Organelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics	20
Quantitative multi-height phase retrieval via a coded image sensor	20
Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples	20
Diagnosis and staging of multiple myeloma using serum-based laser-induced breakdown spectroscopy combined with machine learning methods	20
Phasor-based image segmentation: machine learning clustering techniques	20
Imaging deeper than the transport mean free path with multiphoton microscopy	20
Machine learning model with physical constraints for diffuse optical tomography	20
Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture	20
OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head	20
IA-net: informative attention convolutional neural network for choroidal neovascularization segmentation in OCT images	19
Quantification of scar collagen texture and prediction of scar development via second harmonic generation images and a generative adversarial network	19
In vivo intravascular photoacoustic imaging at a high speed of 100 frames per second	19
Multimodal fusion of EEG-fNIRS: a mutual information-based hybrid classification framework	19
Towards in vivo photoacoustic imaging of vulnerable plaques in the carotid artery	19
Automatic geographic atrophy segmentation using optical attenuation in OCT scans with deep learning	19
Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina	19
In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device	19
Rapid computational cell-rotation around arbitrary axes in 3D with multi-core fiber	19
Humanoid-shaped WaveFlex biosensor for the detection of food contamination	19
Reflective mirror-based line-scan adaptive optics OCT for imaging retinal structure and function	19
A compact photonic resonator absorption microscope for point of care digital resolution nucleic acid molecular diagnostics	19
Understanding the relationship between visual-angle and eye-angle for reliable determination of the field-of-view in ultra-wide field fundus photography	19
Artifact removal in photoacoustic tomography with an unsupervised method	19
Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system	19
Limited-angle tomographic phase microscopy utilizing confocal scanning fluorescence microscopy	19
High-speed multicolor structured illumination microscopy using a hexagonal single mode fiber array	19
Analysis of sensitivity in quantitative micro-elastography	19
Automated phase unwrapping in digital holography with deep learning	19
Deep learning toolbox for automated enhancement, segmentation, and graphing of cortical optical coherence tomography microangiograms	19
Highly sensitive detection of cytochrome c in the NSCLC serum using a hydrophobic paper based–gold nanourchin substrate	19
Measurement of tissue optical properties in a wide spectral range: a review [Invited]	18
Retinal layer segmentation in optical coherence tomography (OCT) using a 3D deep-convolutional regression network for patients with age-related macular degeneration	18
Effects of photobiomodulation on the redox state of healthy and cancer cells	18
Fast, multiplane line-scan confocal microscopy using axially distributed slits	18
Evaluation of bone perfusion during open orthopedic surgery using quantitative dynamic contrast-enhanced fluorescence imaging	18
Complete head cerebral sensitivity mapping for diffuse correlation spectroscopy using subject-specific magnetic resonance imaging models	18
Complex wavelet filter improves FLIM phasors for photon starved imaging experiments	18
First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro intensive care unit	18
Stokes polarization imaging applied for monitoring dynamic tissue optical clearing	18
Comparison between image texture and polarization features in histopathology	18
Deep learning-based single-shot autofocus method for digital microscopy	18
Wavelet-based background and noise subtraction for fluorescence microscopy images	18
Wavefront sensor-less adaptive optics using deep reinforcement learning	18
Machine learning for composition analysis of ssDNA using chemical enhancement in SERS	17
AOTF-based hyperspectral imaging phase microscopy	17
Real-time tool to layer distance estimation for robotic subretinal injection using intraoperative 4D OCT	17
Depth-resolved vascular profile features for artery-vein classification in OCT and OCT angiography of human retina	17
MF-AV-Net: an open-source deep learning network with multimodal fusion options for artery-vein segmentation in OCT angiography	17
Measuring glucose concentration in a solution based on the indices of polarimetric purity	17
Generating large field of view en-face projection images from intra-acquisition motion compensated volumetric optical coherence tomography data	17
Laser-induced optical breakdown effects of micro-lens arrays and diffractive optical elements on ex vivo porcine skin after 1064 nm picosecond laser irradiation	17
Adaptive optics enables aberration-free single-objective remote focusing for two-photon fluorescence microscopy	17
Multi-layer optical fiber surface plasmon resonance biosensor based on a sandwich structure of polydopamine-MoSe2@Au nanoparticles-polydopamine	17

Red and blue light in antitumor photodynamic therapy with chlorin-based photosensitizers: a comparative animal study assisted by optical imaging modalities	17
Real-time OCT image denoising using a self-fusion neural network	17
Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT	17
Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine model for nonalcoholic fatty liver disease	17
Polarimetric data-based model for tissue recognition	17
Histopathology for Mohs micrographic surgery with photoacoustic remote sensing microscopy	17
Machine learning-based rapid diagnosis of human borderline ovarian cancer on second-harmonic generation images	17
Label-free imaging of fibroblast membrane interfaces and protein signatures with vibrational infrared photothermal and phase signals	17
Detection of single-base mutation of DNA oligonucleotides with different lengths by terahertz attenuated total reflection microfluidic cell	16
L1-L2 norm regularization via forward-backward splitting for fluorescence molecular tomography	16
Disrupted signal variability of spontaneous neural activity in children with attention-deficit/hyperactivity disorder	16
Deep learning automated pathology in ex vivo microscopy	16
Moisture adsorption by decellularized bovine pericardium collagen matrices studied by terahertz pulsed spectroscopy and solid immersion microscopy	16
Hyperspectral imaging and spectral unmixing for improving whole-body fluorescence cryo-imaging	16
Spectroscopic detection of traumatic brain injury severity and biochemistry from the retina	16
Terahertz circular polarization sensing for protein denaturation based on a twisted dual-layer metasurface	16
Functional optoretinography: concurrent OCT monitoring of intrinsic signal amplitude and phase dynamics in human photoreceptors	16
Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography	16
FLImBrush: dynamic visualization of intraoperative free-hand fiber-based fluorescence lifetime imaging	16
Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision	16
Probing layered structures by multi-color backscattering polarimetry and machine learning	16
Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography	16
Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography	16
Investigating the depolarization property of skin tissue by degree of polarization uniformity contrast using polarization-sensitive optical coherence tomography	16
Phototoxicity induced in living HeLa cells by focused femtosecond laser pulses: a data-driven approach	16
Kilohertz retinal FF-SS-OCT and flood imaging with hardware-based adaptive optics	16
Dynamic time domain near-infrared optical tomography based on a SPAD camera	16
0.1 THz exposure affects primary hippocampus neuron gene expression via alternating transcription factor binding	16
Full-field spectral-domain optical interferometry for snapshot three-dimensional microscopy	16
Photoacoustic dual-scan mammoscope: results from 38 patients	16
Multi-speckle diffuse correlation spectroscopy to measure cerebral blood flow	16
Empirical assessment of laser safety for photoacoustic-guided liver surgeries	15
Imaging the dynamics of individual processes of microglia in the living retina in vivo	15
Label-free histological imaging of tissues using Brillouin light scattering contrast	15
Shot-noise limited tunable dual-vibrational frequency stimulated Raman scattering microscopy	15
All-fiber few-mode optical coherence tomography using a modally-specific photonic lantern	15
In vivo assessment of corneal biomechanics under a localized cross-linking treatment using confocal air-coupled optical coherence elastography	15
Surgical microscope integrated MHz SS-OCT with live volumetric visualization	15
In vivo assessment of inflammatory bowel disease in rats with ultrahigh-resolution colonoscopic OCT	15
High-fidelity and rapid cellular-level Mueller matrix imaging for tissue identification with unstained sections	15
Evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature	15
Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways	15
Estimation of scleral mechanical properties from air-puff optical coherence tomography	15
Stress management using fNIRS and binaural beats stimulation	15
Performance improvement of a silicon nitride ring resonator biosensor operated in the TM mode at 1310 nm	15
Three-dimensional collagen fiber mapping and tractography of human uterine tissue using OCT	15
Motion-tracking Brillouin microscopy for in-vivo corneal biomechanics mapping	15
Laser-induced fluorescent visualization and photodynamic therapy in surgical treatment of glial brain tumors	15
Single-objective high-resolution confocal light sheet fluorescence microscopy for standard biological sample geometries	15
Open-top axially swept light-sheet microscopy	15
Optical palpation for tumor margin assessment in breast-conserving surgery	15
Dynamic fluorescence lifetime sensing with CMOS single-photon avalanche diode arrays and deep learning processors	15
Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue	15
Multi-camera infrared thermography for infant respiration monitoring	15
Fourier domain diffuse correlation spectroscopy with heterodyne holographic detection	15
Direct mapping from diffuse reflectance to chromophore concentrations in multi-fx spatial frequency domain imaging (SFDI) with a deep residual network (DRN)	15
Single infrared light pulses induce excitatory and inhibitory neuromodulation	15
Polarization and Orbital Angular Momentum of Light in Biomedical Applications: feature issue introduction	15
Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence	15
Line-scanning SD-OCT for in-vivo, non-contact, volumetric, cellular resolution imaging of the human cornea and limbus	15
Direct measurement of the scattering coefficient	14
Second harmonic generation microscopy of otoconia	14
GDCSeg-Net: general optic disc and cup segmentation network for multi-device fundus images	14
Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity	14
Explainable liver tumor delineation in surgical specimens using hyperspectral imaging and deep learning	14
Volumetric Lissajous confocal microscopy with tunable spatiotemporal resolution	14
Evaluation of commercial virtually imaged phase array and Fabry-Pérot based Brillouin spectrometers for applications to biology	14
Fiber-laser platform for precision brain surgery	14
Probe-hosted large area silicon photomultiplier and high-throughput timing electronics for enhanced performance time-domain functional near-infrared spectroscopy	14
Photoacoustic imaging of the spatial distribution of oxygen saturation in an ischemia-reperfusion model in humans	14
Localised light delivery on melanoma cells using optical microneedles	14
Vascular morphology and blood flow signatures for differential artery-vein analysis in optical coherence tomography of the retina	14
A scalable, multi-wavelength, broad bandwidth frequency-domain near-infrared spectroscopy platform for real-time quantitative tissue optical imaging	14
Relative retinal flow velocity detection using optical coherence tomography angiography imaging	14
Analysis of retinal nerve fiber layer birefringence in patients with glaucoma and diabetic retinopathy by polarization sensitive OCT	14
Polarization imaging-based radiomics approach for the staging of liver fibrosis	14
PhaseRMiC: phase real-time microscope camera for live cell imaging	14
Optical detection of formaldehyde in air in the 3.6 µm range	14
Deep-learning-aided forward optical coherence tomography endoscope for percutaneous nephrostomy guidance	14
Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity	14
Exploring the diagnostic value of photoacoustic imaging for breast cancer: the identification of regional photoacoustic signal differences of breast tumors	14
Light transport modeling in highly complex tissues using the implicit mesh-based Monte Carlo algorithm	14
Comparison of confocal and non-confocal split-detection cone photoreceptor imaging	14
Accuracy of diffuse correlation spectroscopy measurements of cerebral blood flow when using a three-layer analytical model	14
Coherence gate shaping for wide field high-resolution in vivo retinal imaging with full-field OCT	13
Rapid non-destructive volumetric tumor yield assessment in fresh lung core needle biopsies using polarization sensitive optical coherence tomography	13
Diatom biosilica in plasmonics: applications in sensing, diagnostics and therapeutics [Invited]	13
Polarization-based probabilistic discriminative model for quantitative characterization of cancer cells	13
An end-to-end network for segmenting the vasculature of three retinal capillary plexuses from OCT angiographic volumes	13
Membranous nephropathy classification using microscopic hyperspectral imaging and tensor patch-based discriminative linear regression	13
Intraoperative colon perfusion assessment using multispectral imaging	13
Optical anisotropy composition of benign and malignant prostate tissues revealed by Mueller-matrix imaging	13
Visual performance after the deterioration of retinal image quality: induced forward scattering using Bangerter foils and fog filters	13
Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging	13
Effect of NIR light on the permeability of the blood-brain barriers in in vitro models	13