Biomedical Optics Express

Article	Citations
Label-free plasmonic immunosensor for cortisol detection in a D-shaped optical fiber	95
Technical considerations in the Verasonics research ultrasound platform for developing a photoacoustic imaging system	61
Multi-scale GCN-assisted two-stage network for joint segmentation of retinal layers and discs in peripapillary OCT images	56
ML-SIM: universal reconstruction of structured illumination microscopy images using transfer learning	55
High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source	54
Machine learning-based LIBS spectrum analysis of human blood plasma allows ovarian cancer diagnosis	50
Quasi-distributed fiber optic sensor-based control system for interstitial laser ablation of tissue: theoretical and experimental investigations	48
Gold nanoparticle enhanced detection of EGFR with a terahertz metamaterial biosensor	46
Convolutional neural network for resolution enhancement and noise reduction in acoustic resolution photoacoustic microscopy	45
Respiratory and heart rate monitoring using an FBG 3D-printed wearable system	44
Terahertz dielectric spectroscopy of human brain gliomas and intact tissues ex vivo: double-Debye and double-overdamped-oscillator models of dielectric response	43
Photoacoustic computed tomography for functional human brain imaging [Invited]	43
Choosing a model for laser speckle contrast imaging	42
Smartphone-based optical spectroscopic platforms for biomedical applications: a review [Invited]	42
Comparative study of the influence of imaging resolution on linear retardance parameters derived from the Mueller matrix	42
Multicolor structured illumination microscopy and quantitative control of polychromatic light with a digital micromirror device	41
Optical ptychography for biomedical imaging: recent progress and future directions [Invited]	40
Photoacoustic-guided surgery from head to toe [Invited]	38
Impact of skin tone on photoacoustic oximetry and tools to minimize bias	38
Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy	37
Imaging of vitreous cortex hyalocyte dynamics using non-confocal quadrant-detection adaptive optics scanning light ophthalmoscopy in human subjects	36
Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation	35
Towards in-vivo label-free detection of brain tumor margins with epi-illumination tomographic quantitative phase imaging	33
Acoustic impact of the human skull on transcranial photoacoustic imaging	33
Rapid and label-free urine test based on surface-enhanced Raman spectroscopy for the non-invasive detection of colorectal cancer at different stages	32

Polarization and depolarization metrics as optical markers in support to histopathology of ex vivo colon tissue	32
Integrating adaptive optics-SLO and OCT for multimodal visualization of the human retinal pigment epithelial mosaic	32
Real-time noise reduction based on ground truth free deep learning for optical coherence tomography	31
Hyperspectral imaging and robust statistics in non-melanoma skin cancer analysis	31
Dual-view oblique plane microscopy (dOPM)	31
Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems	30
Polarimetric visualization of healthy brain fiber tracts under adverse conditions: ex vivo studies	30
Automatic classification of esophageal disease in gastroscopic images using an efficient channel attention deep dense convolutional neural network	30
Applications of augmented reality in ophthalmology [Invited]	30
Wearable device for remote monitoring of transcutaneous tissue oxygenation	29
Evolution of adaptive optics retinal imaging [Invited]	29
Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes	29
Monte Carlo analysis of optical heart rate sensors in commercial wearables: the effect of skin tone and obesity on the photoplethysmography (PPG) signal	29
Twenty-five years of clinical applications using adaptive optics ophthalmoscopy [Invited]	28
Bayesian deep learning for reliable oral cancer image classification	28
Vision-correcting holographic display: evaluation of aberration correcting hologram	27
Strip-based digital image registration for distortion minimization and robust eye motion measurement from scanned ophthalmic imaging systems	27
Deep learning approach to improve tangential resolution in photoacoustic tomography	27
Computational tissue staining of non-linear multimodal imaging using supervised and unsupervised deep learning	27
Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging	27
Auto-detection of cervical collagen and elastin in Mueller matrix polarimetry microscopic images using K-NN and semantic segmentation classification	27
Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography	26
Malignant and benign thyroid nodule differentiation through the analysis of blood plasma with terahertz spectroscopy	26
Model of dynamic speckle evolution for evaluating laser speckle contrast measurements of tissue dynamics	26
Deep-learning based multi-modal retinal image registration for the longitudinal analysis of patients with age-related macular degeneration	26
Deep-learning super-resolution light-sheet add-on microscopy (Deep-SLAM) for easy isotropic volumetric imaging of large biological specimens	25
Terahertz dielectric spectroscopy and solid immersion microscopy of ex vivo glioma model 101.8: brain tissue heterogeneity	25
Effects of high intensity non-ionizing terahertz radiation on human skin fibroblasts	25
Dual GRIN lens two-photon endoscopy for high-speed volumetric and deep brain imaging	25
Adaptive optics for optical microscopy [Invited]	25
Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy	25
Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast	24
Quantitative structural imaging of keratoconic corneas using polarization-resolved SHG microscopy	24
Automatic geographic atrophy segmentation using optical attenuation in OCT scans with deep learning	24
Transfontanelle photoacoustic imaging: ultrasound transducer selection analysis	24
Multi-spectral intravascular photoacoustic/ultrasound/optical coherence tomography tri-modality system with a fully-integrated 0.9-mm full field-of-view catheter for plaque vulnerability imaging	24
Robust non-contact peripheral oxygenation saturation measurement using smartphone-enabled imaging photoplethysmography	24
Weakly supervised anomaly segmentation in retinal OCT images using an adversarial learning approach	23
Optical design and performance of a trifocal sinusoidal diffractive intraocular lens	23
Resolution enhancement and realistic speckle recovery with generative adversarial modeling of micro-optical coherence tomography	23
Machine learning model with physical constraints for diffuse optical tomography	23
Optimizing deep bone ablation by means of a microsecond Er:YAG laser and a novel water microjet irrigation system	23
Sustained fatigue assessment during isometric exercises with time-domain near infrared spectroscopy and surface electromyography signals	23
Wavelength and pulse energy optimization for detecting hypoxia in photoacoustic imaging of the neonatal brain: a simulation study	23
Understanding the relationship between visual-angle and eye-angle for reliable determination of the field-of-view in ultra-wide field fundus photography	23
A compact photonic resonator absorption microscope for point of care digital resolution nucleic acid molecular diagnostics	22
Miniature structured illumination microscope for in vivo 3D imaging of brain structures with optical sectioning	22
Imaging deeper than the transport mean free path with multiphoton microscopy	22
Non-contact terahertz spectroscopic measurement of the intraocular pressure through corneal hydration mapping	21
Organelle-specific phase contrast microscopy enables gentle monitoring and analysis of mitochondrial network dynamics	21

Optical property recovery with spatially-resolved diffuse reflectance at short source-detector separations using a compact fiber-optic probe	21
Large-scale, cell-resolution volumetric mapping allows layer-specific investigation of human brain cytoarchitecture	21
Quantitative Jones matrix imaging using vectorial Fourier ptychography	21
Complete head cerebral sensitivity mapping for diffuse correlation spectroscopy using subject-specific magnetic resonance imaging models	21
Quantitative multi-height phase retrieval via a coded image sensor	21
Multimodal fusion of EEG-fNIRS: a mutual information-based hybrid classification framework	21
Towards in vivo photoacoustic imaging of vulnerable plaques in the carotid artery	21
Measurement of tissue optical properties in a wide spectral range: a review [Invited]	21
Evaluation of the robustness of cerebral oximetry to variations in skin pigmentation using a tissue-simulating phantom	21
Limited-angle tomographic phase microscopy utilizing confocal scanning fluorescence microscopy	21
Analysis of sensitivity in quantitative micro-elastography	21
Automated phase unwrapping in digital holography with deep learning	21
Ultrahigh-speed multimodal adaptive optics system for microscopic structural and functional imaging of the human retina	20
Diagnosis and staging of multiple myeloma using serum-based laser-induced breakdown spectroscopy combined with machine learning methods	20
Humanoid-shaped WaveFlex biosensor for the detection of food contamination	20
High-speed multicolor structured illumination microscopy using a hexagonal single mode fiber array	20
OCT-GAN: single step shadow and noise removal from optical coherence tomography images of the human optic nerve head	20
In vivo functional imaging of the human middle ear with a hand-held optical coherence tomography device	20
Deep learning-based single-shot autofocus method for digital microscopy	20
Phasor-based image segmentation: machine learning clustering techniques	20
First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro intensive care unit	20
Artifact removal in photoacoustic tomography with an unsupervised method	20
Retinal layer segmentation in optical coherence tomography (OCT) using a 3D deep-convolutional regression network for patients with age-related macular degeneration	20
Reflective mirror-based line-scan adaptive optics OCT for imaging retinal structure and function	20
Deep learning toolbox for automated enhancement, segmentation, and graphing of cortical optical coherence tomography microangiograms	20
Surgical microscope integrated MHz SS-OCT with live volumetric visualization	19
Laser-induced optical breakdown effects of micro-lens arrays and diffractive optical elements on ex vivo porcine skin after 1064 nm picosecond laser irradiation	19
MF-AV-Net: an open-source deep learning network with multimodal fusion options for artery-vein segmentation in OCT angiography	19
Highly sensitive detection of cytochrome c in the NSCLC serum using a hydrophobic paper based–gold nanourchin substrate	19
Quantification of scar collagen texture and prediction of scar development via second harmonic generation images and a generative adversarial network	19
Adaptive optics enables aberration-free single-objective remote focusing for two-photon fluorescence microscopy	19
Multi-layer optical fiber surface plasmon resonance biosensor based on a sandwich structure of polydopamine-MoSe2@Au nanoparticles-polydopamine	19
Stokes polarization imaging applied for monitoring dynamic tissue optical clearing	19
Light-adapted flicker optoretinograms captured with a spatio-temporal optical coherence-tomography (STOC-T) system	19
Wavelet-based background and noise subtraction for fluorescence microscopy images	19
AOTF-based hyperspectral imaging phase microscopy	19
Real-time tool to layer distance estimation for robotic subretinal injection using intraoperative 4D OCT	19
Wavefront sensor-less adaptive optics using deep reinforcement learning	19
Rapid computational cell-rotation around arbitrary axes in 3D with multi-core fiber	19
Identification and quantification of fibrotic areas in the human retina using polarization-sensitive OCT	18
Effects of photobiomodulation on the redox state of healthy and cancer cells	18
Measuring glucose concentration in a solution based on the indices of polarimetric purity	18
Comparison between image texture and polarization features in histopathology	18
0.1 THz exposure affects primary hippocampus neuron gene expression via alternating transcription factor binding	18
Polarimetric data-based model for tissue recognition	18
Fast, multiplane line-scan confocal microscopy using axially distributed slits	18
Terahertz circular polarization sensing for protein denaturation based on a twisted dual-layer metasurface	18
Complex wavelet filter improves FLIM phasors for photon starved imaging experiments	18
Volumetric growth tracking of patient-derived cancer organoids using optical coherence tomography	18
Real-time OCT image denoising using a self-fusion neural network	18
Disrupted signal variability of spontaneous neural activity in children with attention-deficit/hyperactivity disorder	17
Moisture adsorption by decellularized bovine pericardium collagen matrices studied by terahertz pulsed spectroscopy and solid immersion microscopy	17
Photoacoustic dual-scan mammoscope: results from 38 patients	17
Accuracy of diffuse correlation spectroscopy measurements of cerebral blood flow when using a three-layer analytical model	17
Machine learning-based rapid diagnosis of human borderline ovarian cancer on second-harmonic generation images	17
Label-free imaging of fibroblast membrane interfaces and protein signatures with vibrational infrared photothermal and phase signals	17
Phototoxicity induced in living HeLa cells by focused femtosecond laser pulses: a data-driven approach	17
Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography	17
Estimation of scleral mechanical properties from air-puff optical coherence tomography	17
Performance improvement of a silicon nitride ring resonator biosensor operated in the TM mode at 1310 nm	17
Histopathology for Mohs micrographic surgery with photoacoustic remote sensing microscopy	17
Single-objective high-resolution confocal light sheet fluorescence microscopy for standard biological sample geometries	17
Line-scanning SD-OCT for in-vivo, non-contact, volumetric, cellular resolution imaging of the human cornea and limbus	17
Imaging the dynamics of individual processes of microglia in the living retina in vivo	17
Stress management using fNIRS and binaural beats stimulation	17
Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision	17
Hyperspectral imaging and spectral unmixing for improving whole-body fluorescence cryo-imaging	17
Depth-resolved vascular profile features for artery-vein classification in OCT and OCT angiography of human retina	17
Red and blue light in antitumor photodynamic therapy with chlorin-based photosensitizers: a comparative animal study assisted by optical imaging modalities	17
Evaluation of resonant scanning as a high-speed imaging technique for two-photon imaging of cortical vasculature	17
Functional optoretinography: concurrent OCT monitoring of intrinsic signal amplitude and phase dynamics in human photoreceptors	17
Generating large field of view en-face projection images from intra-acquisition motion compensated volumetric optical coherence tomography data	17
Localised light delivery on melanoma cells using optical microneedles	16
Dynamic fluorescence lifetime sensing with CMOS single-photon avalanche diode arrays and deep learning processors	16
Characterization and quantification of necrotic tissues and morphology in multicellular ovarian cancer tumor spheroids using optical coherence tomography	16
All-fiber few-mode optical coherence tomography using a modally-specific photonic lantern	16
In vivo assessment of corneal biomechanics under a localized cross-linking treatment using confocal air-coupled optical coherence elastography	16
Probing layered structures by multi-color backscattering polarimetry and machine learning	16
Continuous spectral zooming for in vivo live 4D-OCT with MHz A-scan rates and long coherence	16
L1-L2 norm regularization via forward-backward splitting for fluorescence molecular tomography	16

Dynamic microscopic optical coherence tomography to visualize the morphological and functional micro-anatomy of the airways	16
Refractive-index matching enhanced polarization sensitive optical coherence tomography quantification in human brain tissue	16
Deep learning automated pathology in ex vivo microscopy	16
Fiber-laser platform for precision brain surgery	16
Intraoperative colon perfusion assessment using multispectral imaging	16
Open-top axially swept light-sheet microscopy	16
Investigating the depolarization property of skin tissue by degree of polarization uniformity contrast using polarization-sensitive optical coherence tomography	16
Empirical assessment of laser safety for photoacoustic-guided liver surgeries	16
A scalable, multi-wavelength, broad bandwidth frequency-domain near-infrared spectroscopy platform for real-time quantitative tissue optical imaging	16
Versatile, do-it-yourself, low-cost spinning disk confocal microscope	16
Polarization and Orbital Angular Momentum of Light in Biomedical Applications: feature issue introduction	16
In vivo assessment of inflammatory bowel disease in rats with ultrahigh-resolution colonoscopic OCT	16
Motion-tracking Brillouin microscopy for in-vivo corneal biomechanics mapping	15
Single infrared light pulses induce excitatory and inhibitory neuromodulation	15
Optical detection of formaldehyde in air in the 3.6 µm range	15
Analysis and improvement of non-contact SpO2 extraction using an RGB webcam	15
Massively parallel, real-time multispeckle diffuse correlation spectroscopy using a 500 × 500 SPAD camera	15
Laser-induced fluorescent visualization and photodynamic therapy in surgical treatment of glial brain tumors	15
High-fidelity and rapid cellular-level Mueller matrix imaging for tissue identification with unstained sections	15
Deep-learning-aided forward optical coherence tomography endoscope for percutaneous nephrostomy guidance	15
Multi-scale laser speckle contrast imaging of microcirculatory vasoreactivity	15
Light transport modeling in highly complex tissues using the implicit mesh-based Monte Carlo algorithm	15
Direct mapping from diffuse reflectance to chromophore concentrations in multi-fx spatial frequency domain imaging (SFDI) with a deep residual network (DRN)	15
Rapid non-destructive volumetric tumor yield assessment in fresh lung core needle biopsies using polarization sensitive optical coherence tomography	15
Fusion deep learning approach combining diffuse optical tomography and ultrasound for improving breast cancer classification	15
Optical palpation for tumor margin assessment in breast-conserving surgery	15
Label-free histological imaging of tissues using Brillouin light scattering contrast	15
Shot-noise limited tunable dual-vibrational frequency stimulated Raman scattering microscopy	15
Fourier ptychography multi-parameter neural network with composite physical priori optimization	14
Explainable liver tumor delineation in surgical specimens using hyperspectral imaging and deep learning	14
Evaluation of commercial virtually imaged phase array and Fabry-Pérot based Brillouin spectrometers for applications to biology	14
Diatom biosilica in plasmonics: applications in sensing, diagnostics and therapeutics [Invited]	14
Vascular morphology and blood flow signatures for differential artery-vein analysis in optical coherence tomography of the retina	14
Direct measurement of the scattering coefficient	14
Laser speckle imaging for early detection of microbial colony forming units	14
Volumetric tumor delineation and assessment of its early response to radiotherapy with optical coherence tomography	14
Depth-resolved visualization and automated quantification of hyperreflective foci on OCT scans using optical attenuation coefficients	14
Portable widefield fundus camera with high dynamic range imaging capability	14
Exploring the diagnostic value of photoacoustic imaging for breast cancer: the identification of regional photoacoustic signal differences of breast tumors	14
Noninvasive measurement of the vital signs of cancer patients with a dual-path microbend fiber sensor	14
Comparison of confocal and non-confocal split-detection cone photoreceptor imaging	14
Recent advances in optical elastography and emerging opportunities in the basic sciences and translational medicine [Invited]	14
Polarization imaging-based radiomics approach for the staging of liver fibrosis	14
Effect of NIR light on the permeability of the blood-brain barriers in in vitro models	14
Second harmonic generation microscopy of otoconia	14
PhaseRMiC: phase real-time microscope camera for live cell imaging	14
Estimation of the full shape of the crystalline lens in-vivo from OCT images using eigenlenses	14
GDCSeg-Net: general optic disc and cup segmentation network for multi-device fundus images	14
Real-time pixelwise phasor analysis for video-rate two-photon fluorescence lifetime imaging microscopy	14
Deep learning-based optical coherence tomography image analysis of human brain cancer	14
Toward a quantitative method for estimating tumour-stroma ratio in breast cancer using polarized light microscopy	14
Exoscope-based videocapillaroscopy system for in vivo skin microcirculation imaging of various body areas	14
Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits	14
Visual performance after the deterioration of retinal image quality: induced forward scattering using Bangerter foils and fog filters	14
MicroHikari3D: an automated DIY digital microscopy platform with deep learning capabilities	14
Analyzing the serum of hemodialysis patients with end-stage chronic kidney disease by means of the combination of SERS and machine learning	14
Polarization-based probabilistic discriminative model for quantitative characterization of cancer cells	14
Time-domain NIRS system based on supercontinuum light source and multi-wavelength detection: validation for tissue oxygenation studies	14
Photoacoustic imaging of the spatial distribution of oxygen saturation in an ischemia-reperfusion model in humans	14
Direct characterization of tissue dynamics with laser speckle contrast imaging	14
Low noise, self-phase-modulation-enabled femtosecond fiber sources tunable in 740-1236 nm for wide two-photon fluorescence microscopy applications	14
Fast digital refocusing and depth of field extended Fourier ptychography microscopy	14
OCT-OCTA segmentation: combining structural and blood flow information to segment Bruch’s membrane	14
Backscattering polarimetric imaging of the human brain to determine the orientation and degree of alignment of nerve fiber bundles	13
Terahertz phase shift sensing and identification of a chiral amino acid based on a protein-modified metasurface through the isoelectric point and peptide bonding	13
An end-to-end network for segmenting the vasculature of three retinal capillary plexuses from OCT angiographic volumes	13
Deep neural network classification of in vivo burn injuries with different etiologies using terahertz time-domain spectral imaging	13
Label-free intratissue activity imaging of alveolar organoids with dynamic optical coherence tomography	13
Most favorable stimulation duration in the sensorimotor cortex for fNIRS-based BCI	13
Dual-view light-sheet imaging through a tilted glass interface using a deformable mirror	13
Stent detection with very thick tissue coverage in intravascular OCT	13
Bessel-beam illumination Raman microscopy	13
Optimizing the OCTA layer fusion option for deep learning classification of diabetic retinopathy	13
Discriminating turbid media by scatterer size and scattering coefficient using backscattered linearly and circularly polarized light	13
Classification of two species of Gram-positive bacteria through hyperspectral microscopy coupled with machine learning	13
Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study	13
Aberration measurement and correction on a large field of view in fluorescence microscopy	13
Robotic-arm-assisted flexible large field-of-view optical coherence tomography	13
Quantitative evaluation of the dynamic activity of HeLa cells in different viability states using dynamic full-field optical coherence microscopy	13
Effect of adipose tissue thickness and tissue optical properties on the differential pathlength factor estimation for NIRS studies on human skeletal muscle	13
Fast optical coherence tomography angiography image acquisition and reconstruction pipeline for skin application	13
Speckle statistics of biological tissues in optical coherence tomography	13
Low-consumption photoacoustic method to measure liquid viscosity	13
High-Q Fano resonances in all-dielectric metastructures for enhanced optical biosensing applications	13
Clinical integration of fast Raman spectroscopy for Mohs micrographic surgery of basal cell carcinoma	13
Connectivity-based deep learning approach for segmentation of the epithelium in in vivo human esophageal OCT images	13
Fluorescence lifetime needle optical biopsy discriminates hepatocellular carcinoma	13
Membranous nephropathy classification using microscopic hyperspectral imaging and tensor patch-based discriminative linear regression	13
Centimeter-scale wide-field-of-view laser-scanning photoacoustic microscopy for subcutaneous microvasculature in vivo	13
Numerical calibration method for a multiple spectrometer-based OCT system	13
Non-invasive visualization of amyloid-beta deposits in Alzheimer amyloidosis mice using magnetic resonance imaging and fluorescence molecular tomography	13
Influence of hematoxylin and eosin staining on the quantitative analysis of second harmonic generation imaging of fixed tissue sections	13
Common-path intrinsically achromatic optical diffraction tomography	13
Quantitative and anatomical imaging of dermal angiopathy by noninvasive photoacoustic microscopic biopsy	13
Optical anisotropy composition of benign and malignant prostate tissues revealed by Mueller-matrix imaging	13