Aging and Disease

Article	Citations
Burn Injuries Accelerate Biological Aging and Increase the Epigenetically Inferred Risk of Mortality and Frailty	137
Revisiting the Role of Mitochondrial DNA Mutations in Aging: Bridging Theoretical Expectations with Empirical Observations	126
Aligning Intrinsic Capacity and Geroscience: Linking Function with Biology	122
The HLA-B*57:01 Haplotype, Genetic Key Linking Innate Immunity and Longevity	89
Vascular Contributions to Healthy Aging and Dementia	89
Correlations between Aging, Telomeres, and Natural Compounds	89
Neuropsychological Profiles in Genetic Frontotemporal Dementia: A Meta-Analysis and Systematic Review	75
Updates in Intravenous Thrombolysis Treatment for Acute Ischemic Stroke in Asian Populations	74
KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging	73
Exploiting the Fractionation of Stable Isotopes in Biochemical Processes for Medical Diagnosis: A Narrative Review	67
Quantum Sensing for Precision Organ Aging Assessment	66
Retinal Pigment Epithelium Phagocytosis and Retinal Degenerative Diseases	65
Astrocytic Ferroptosis: An Integrative Hub Linking Metabolic Dyshomeostasis, Glial Crosstalk, and Neurodegeneration in Alzheimer’s Disease	63
Axonal Energy Crisis and Calcium Phosphate Dysregulation as Pathogenesis of Optic Disc Drusen	63
The Dickkopf Protein Family in Non-Neoplastic Disorders: Emerging Roles and Therapeutic Targeting	59
The Roles of T cells in Immune Checkpoint Inhibitor-Induced Arthritis	59
Cross-Tissue Proteomic Mendelian Randomization Identifies Therapeutic Targets for Vascular Dementia	59
A Biological Alignment Framework for Interpreting Anti-Inflammatory Cardiovascular Trials in Atherosclerosis	58
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization	58
Astrocyte-Microglia Crosstalk: A Novel Target for the Treatment of Migraine	58
Metabolic Dysregulation in Parkinson’s Disease: Non-Oxidative Phosphorylation and Its Role in Brain Energy Metabolism	56
IRG1/Itaconate Inhibits Microglial Senescence-Like Transition by Modulating Mitochondrial Dynamics through Rhoa Alkylation in Subarachnoid Hemorrhage	54
Staging of Neuropil Morphological Alterations in Alzheimer’s Disease	54
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung	53
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies	51

Functional Imaging in Osteoarthritis: Bridging Mechanistic Insight and Therapeutic Translation	51
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies	50
Vascular Aging and Atherosclerosis: A Perspective on Aging	49
Lysine Malonylation and Its Links to Metabolism and Diseases	49
A Systematic Review of Intervention Trials Utilizing Biomarkers Among Informal Caregivers of People with Alzheimer's Disease & Related Dementias	48
Unmet Medication Needs and the Association with Mortality in Older Adults: Equality-Oriented Monitoring toward Universal Health Coverage	47
Early Risk Prediction Model for Stroke-Heart Syndrome Following Endovascular Therapy	47
Apolipoprotein CII: Cornerstone of Pathophysiological Interplay in Aortic Stenosis and type 2 Diabetes Mellitus	46
VCAM-1 in Cognitive Impairment: Mechanisms, Biomarker Potential, and Therapeutic Targeting	43
Mitochondrial Dysfunction of Astrocytes Mediates Lipid Accumulation in Temporal Lobe Epilepsy	42
Aβ Deposition in Extracellular Space Disrupts Glial-Neuron Communication and Triggers Alzheimer's Disease	41
Overcoming Extracellular Matrix Barriers: Biomaterial-Assisted microRNA Delivery for Fibrous Musculoskeletal Regeneration	41
Stroke-Induced Retinal Dysfunction: Mechanisms, Diagnostics, and Future Directions	40
Endogenous Retroviruses Unveiled: A Comprehensive Review of Inflammatory Signaling/Senescence-Related Pathways and Therapeutic Strategies	39
Autophagy in Disease Onset and Progression	39
Beyond Amyloid: Rethinking the Foundations of Alzheimer’s Disease Pathogenesis and Therapy	39
Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer	39
Immunosenescence: Shaping the Hematological Narrative in the Era of Aging	39
Dopamine-Induced L-Lactate Production in Cortical Astrocytes Cross-Reacts with β1-Adrenoceptor-Mediated cAMP Signalling	38
Delphi-derived Framework for Healthspan-Oriented Care: The Cardiometabolic Health Perspective	37
Telomeres: Dysfunction, Maintenance, Aging and Cancer	37
Age-, sex-, and ancestry-specific prevalence of hearing loss in UK Biobank and All of Us Research Program	36
Spinal Cord Injury and Ageing: The Role of Chronic Neuroinflammation	36
Aging and “Age-Related” Diseases - What Is the Relation?	36
Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis	36
Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the LmnaG609G/G609G Mouse Model of Progeria	33
Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis	33
Role of AMPK and Sirtuins in Aging Heart: Basic and Translational Aspects	33
Healthy Human Fecal Microbiota Transplantation into Mice Attenuates MPTP-Induced Neurotoxicity via AMPK/SOD2 Pathway	33
Nanozyme-Based Strategies in Cancer Immunotherapy: Overcoming Resistance to Enhance Therapeutic Efficacy	33
EchoAGE: Echocardiography-based Neural Network Model Forecasting Heart Biological Age	33
Microcirculation Dysfunction in Subacute Stroke: The Role of Delayed Capillary Pericyte Loss	32
NAD+ Metabolism and Mitochondrial Activity in the Aged Oocyte: Focus on the Effects of NAMPT Stimulation	31
Applications of Chitosan and its Derivatives in the Treatment of Osteoarthritis	30
Epidural Pulsation Accelerates the Drainage of Brain Interstitial Fluid	30
Visual Dependence in Postural Control Is Increased in Older Adults	30
Advancing Single-Cell Transcriptomic Analysis to Reveal Age-Related Skeletal Muscle Changes: A Systematic Review	29
Semaphorins: Missing Signals in Age-dependent Alteration of Neuromuscular Junctions and Skeletal Muscle Regeneration	29
Revisiting Skeletal Muscle Dysfunction and Exercise in Chronic Obstructive Pulmonary Disease: Emerging Significance of Myokines	27
Multimodal In Vivo Imaging Reveals BZBS Capsules Enhance Brain Function and Delay Aging in the Mouse Models	27
(Dys)regulation of the Immune System in Parkinson’s Disease: Methodologies, Techniques, and Key Findings from Human Studies	27
Single Cell RNAseq Analysis of Thyroid Hormone Effects on Retinal Glial Cells	26
Histone Methylation, Energy Metabolism, and Alzheimer's Disease	26
The Comorbidity of AD and PD: Exploring Clinical, Pathological, and Biomarker Interactions	26
Mortality Outcomes in a Large Population with and without Covert Cerebrovascular Disease	25
Role of Microglia, Decreased Neurogenesis and Oligodendrocyte Depletion in Long COVID-Mediated Brain Impairments	25
Repurposing Ketamine in the Therapy of Depression and Depression-Related Disorders: Recent Advances and Future Potential	25
Elderly Dementia Needs Better Care in Post-COVID-19 Era	25
Epigenetic Clocks Identify Harmful Epigenetic Aging Linked to Depression Severity and Cognitive Deficits in Major Depressive Disorder	24
Schizophrenia-Like Behaviors Arising from Dysregulated Proline Metabolism Are Associated with Altered Neuronal Morphology and Function in Mice with Hippocampal PRODH Deficiency	24

New Clues to Cardiovascular Disease: Erythrocyte Lifespan	24
Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses	23
Mitochondrial Dysfunction: A Roadmap for Understanding and Tackling Cardiovascular Aging	23
Fecal Microbiota Transplantation Attenuates Frailty via Gut-Muscle Axis in Old Mice	23
Different Aspects of Aging in Migraine	23
Chronobiology of the Tumor Microenvironment: Implications for Therapeutic Strategies and Circadian-Based Interventions	22
Mechanistic Insights and Emerging Therapeutic Targets of Alzheimer's Disease: From the Perspective of Inter-Organ Crosstalk	22
SARM1 Promotes Neurodegeneration and Memory Impairment in Mouse Models of Alzheimer's Disease	22
Hexokinase as a Central Hub in Neurodegeneration: From Metabolic Dysfunction to Therapeutic Innovation	22
Minocycline Administration Does Not Have an Effect on Retinal Ganglion Cell Survival in a Murine Model of Ocular Hypertension	22
Potential of Neuroinflammation-Modulating Strategies in Tuberculous Meningitis: Targeting Microglia	21
Expanding on Gut Microbiota Insights in Sarcopenia and Osteoporosis	21
A Signature of Senescence Based on An Analysis of Selected Markers in Primary Vascular Smooth Muscle Cells Cultured In Vitro and Derived from Atherosclerotic Plaque	21
Stroke Exacerbates Respiratory Disorder and Cognition Impairment in Mice with Cerebral Amyloid Angiopathy	21
The Lung-Brain Axis in Cognitive Impairment and Dementia: Mechanisms and Therapeutic Prospects	21
Health Related Quality of Life in Adults with 13 Chronic Diseases before Age 65 and after Age 65 Using Fuzzy Rough Analysis of SF-36 Domains	20
Biomarkers of Parkinson’s Disease: From Basic Research to Clinical Practice	20
Spatiotemperal Dynamics of Osteoarthritis: Bridging Insights from Bench to Bedside	20
Emerging Roles of Adaptive Immune Response in Alzheimer's Disease	20
Long-Term Improvement in Hippocampal-Dependent Learning Ability in Healthy, Aged Individuals Following High Intensity Interval Training	19
Senescent T Cells in Age-Related Diseases	19
Astrocyte-Derived Extracellular Vesicles for Ischemic Stroke: Therapeutic Potential and Prospective	19
Targeting Mitochondrial Sirtuins in Age-Related Neurodegenerative Diseases and Fibrosis	19
Irisin: A Potentially Fresh Insight into the Molecular Mechanisms Underlying Vascular Aging	19
Aberrantly High FBXO31 Impairs Oocyte Quality in Premature Ovarian Insufficiency	19
Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD	19
The Interplay Between Physical Exercise, Nutritional Strategies, and Brain-Derived Neurotrophic Factor in Promoting Cognitive Performance	19
Circadian Rhythm, Clock Genes and Osteoarthritis: The Dream of a Good Night’s Sleep	18
Time and Tissue Windows in Futile Reperfusion after Ischemic Stroke	18
Postbiotic Parabacteroides Distasonis Supplementation Enhances Intestinal and Skeletal Muscle Function in Aged Mice	18
The Role of Liquid-Liquid Phase Separation in the Accumulation of Pathological Proteins: New Perspectives on the Mechanism of Neurodegenerative Diseases	18
Rapamycin Attenuates Age-Related Changes in Marmoset Submandibular Gland: A Non-Human Primate Model of Human Oral Aging	18
Conceptual Overview of Biological Age Estimation	18
Identification of Cathepsin B as a Therapeutic Target for Ferroptosis of Macrophage after Spinal Cord Injury	18
Probiotic Limosilactobacillus Reuteri (Lactobacillus Reuteri) Extends the Lifespan of Drosophila Melanogaster through Insulin/IGF-1 Signaling	18
The Emerging Role of the Mitochondrial Respiratory Chain in Skeletal Aging	18
Advancing Neurological Health: Insights into Aging, Immunity, and Vascular Dynamics	17
Molecular Mechanisms of Phase Separation and Amyloidosis of ALS/FTD-linked FUS and TDP-43	17
Establishing Predictors of Acute Sarcopenia: A Proof-Of-Concept Study Utilising Network Analysis	17
Oligomeric β-Amyloid Suppresses Hippocampal γ-Oscillations through Activation of the mTOR/S6K1 Pathway	17
A Standardized Protocol for Mouse Longevity Studies in Preclinical Drug Development	17
CAG Repeat Expansions Increase N1-Methyladenine to Alter TDP-43 Phase Separation: Lights Up Therapeutic Intervention for Neurodegeneration	17
Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects	17
Metformin Treatment Leads to Increased HIV Transcription and Gene Expression through Increased CREB Phosphorylation and Recruitment to the HIV LTR Promoter	17
Engineering the Future of Longevity R&D: The Case for AI-Driven, Integrated Biotechnology Ecosystems	16
Perspectives on Pathological Crosstalk between Malocclusion and Multi-organ Systems: The Hidden Face of an Iceberg	16
Aging Intensifies Myeloperoxidase Activity after Ischemic Stroke	16
Resveratrol: Harnessing Nature's Potential for Chronic Pain Relief	16
Alpha-Glucosidase Inhibitors in Aging and Aging-Related Diseases: Clinical Applications and Relevant Mechanisms	16
CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and Astrocytes	15
Crossing Pathological Boundaries: Multi-Target Restoration of the Neurovascular Unit in Alzheimer's and Vascular Dementia—From Modern Therapeutics to Traditional Chinese Medicine	15
Prolonged Mild Sleep Restriction Changes Epigenome-Wide DNA Methylation in Peripheral Blood Cells: A Randomized Crossover Trial	15
Bone Regeneration Enhanced by Quercetin-Capped Selenium Nanoparticles via miR206/Connexin43, WNT, and BMP signaling pathways	15
Mitochondria: A Potential Rejuvenation Tool against Aging	15
Association Between Dementia and Optical Coherence Tomography Scan Quality	15
The Greater Omentum: Multifaceted Interactions in Neurological Recovery and Disease Progression	15
Melatonin and Prostate Cancer: Anti-tumor Roles and Therapeutic Application	14
Brain Insulin Signaling is Associated with Late-Life Cognitive Decline	14
Mind the Metabolic Gap: Bridging Migraine and Alzheimer's disease through Brain Insulin Resistance	14
A C. elegans-to-Mouse Discovery Framework for Prioritizing Sarcopenia Interventions	14
Ovariectomy and High Fat-Sugar-Salt Diet Induced Alzheimer's Disease/Vascular Dementia Features in Mice	14
Neuronal Senescence in the Aged Brain	14
Redefinition of Synovial Fibroblasts in Rheumatoid Arthritis	14
Interconnected Pathways of Alzheimer's Disease and Osteoporosis: A Review of Genetic, Hormonal, and Environmental Influences	13
Gut Microbiota is an Impact Factor based on the Brain-Gut Axis to Alzheimer’s Disease: A Systematic Review	13
Microglial Histaminergic Signaling Promotes Interleukin-10 Production and Ameliorates Motor Dysfunction in Parkinson's Disease	13
Critical Considerations for Mesenchymal Stem Cell-based Therapies in Osteoarthritis and Spinal Cord Injury: A Narrative Review	13
Osteoporosis in Relation to a Bone-Related Aging Biomarker Derived from the Urinary Proteomic Profile: A Population Study	13
Shedding Light on the Interaction Between Rif1 and Telomeres in Ovarian Cancer	13
Hypoxic Preconditioning Mitigates Acute Hypoxia Induced MS/VDB Cholinergic Cell Loss and Memory Impairments	13
Neurofilament-Light Chain and Glial Fibrillary Acidic Protein as Blood-Based Delirium Risk Markers: A Multicohort Study	13
Spinal cord changes in Neurodegenerative and Neuroinflammatory Diseases	13
Disulfidptosis, A Novel Cell Death Pathway: Molecular Landscape and Therapeutic Implications	13
Plasma GFAP and Amyloid Pathology Predict Cognitive Response to Multidomain Interventions in MCI	13
Lars2 Deficiency-Induced Mitochondrial Dysfunction Drives the Emergence of a Pro-Inflammatory Stroke-Specific Microglial Subpopulation	13
Mechanisms and Pathogenesis of Diabetic Cognitive Impairment: A Comprehensive Review	13
Male Monocyte-Like Cells are Prone to a Senescence-Induced Pro-inflammatory State	12
Epigenetic Regulation of Regulated Cell Death in Aging-Related Diseases: Clinical Perspectives	12
Plasma Neurodegenerative Biomarkers in Cognitively Preserved Nonagenarians	12
Biological Age Should Anchor Age-Related Disease Research	12

Deep Learning Based on Computed Tomography Predicts Response to Chemoimmunotherapy in Lung Squamous Cell Carcinoma	12
Lamotrigine Restores Impairments in Theta Rhythms and LTP as Early Biomarkers of Aβ1-42-Induced Hippocampal Network Dysfunction	12
Interthalamic Adhesion as a Potential Structural Regulator of Cerebrospinal Fluid Dynamics in the Third Ventricle	12
Pros and Cons of Human Brain Organoids to Study Alzheimer’s Disease	12
Inhibiting Glutaminase Exerts Opposite Effects on Ovariectomy-Induced and Age-Related Reductions in Murine Bone Mass	11
Community-Based Ocular Screening Integrated into Primary Healthcare for Older Adults: Design and 2-Year Follow-Up Results	11
Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations	11
Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice	11
Cardiovascular Health, as per Life's Essential 8, and Impaired Lower-Extremity Function in Older Adults	11
Revolutionizing Senescence Detection: Advancements from Traditional Methods to Cutting-Edge Techniques	11
A Potential “Anti-Warburg Effect” in Circulating Tumor Cell-mediated Metastatic Progression?	11
Aging Gut Microbiome in Healthy and Unhealthy Aging	11
Changes in Plasma Neutral and Ether-Linked Lipids Are Associated with The Pathology and Progression of Alzheimer’s Disease	11
Responsiveness to Tocilizumab in Anti-Acetylcholine Receptor-Positive Generalized Myasthenia Gravis	11
Age-Related Hormones Changes and Its Impact on Health Status and Lifespan	11
Sirtuins at the Crossroads between Mitochondrial Quality Control and Neurodegenerative Diseases: Structure, Regulation, Modifications, and Modulators	11
Crosstalk between Circadian Rhythm Dysregulation and Tumorigenesis, Tumor Metabolism and Tumor Immune Response	11
Apolipoprotein ε in Brain and Retinal Neurodegenerative Diseases	10
Profile for Brain Disease Research Infrastructure for Data Gathering and Exploration (BRIDGE) Platform	10
A longitudinal Analysis of the Association between Socioeconomic Position and Multimorbidity in the European Prospective Investigation into Cancer and Nutrition Study	10
YAP/TAZ as Molecular Targets in Skeletal Muscle Atrophy and Osteoporosis	10
Optimal Evaluation and Treatment of Cardiac Rehabilitation for Patients Following TAVR: A Personalized Program Based on The Five Prescriptions	10
Sex- and Age-Dependent Metabolic and Inflammatory Pathways in Cardiomyopathy: The Role of Sirtuins, Inflammaging and Mitochondrial Homeostasis	10
Neuroserpin and Extracellular Vesicles in Ischemic Stroke: Partners in Neuroprotection?	10
Aging Biomarkers in Osteoporosis: A Systematic Review of Molecular Mechanisms, Biological Aging, and Population Evidence	10
Genetic Risk, Inflammation, and Therapeutics: An Editorial Overview of Recent Advances in Aging Brains and Neurodegeneration	10
Traveling Subject-Informed Harmonization Increases Reliability of Brain Diffusion Tensor and Neurite Mapping	10
Comprehensive Review of Therapeutic Efficacy and Underlying Mechanisms of Various Exercise Modalities in Treating Osteoporosis	10
Bidirectional Crosstalk between the Heart and Brain in Alzheimer's Disease	10
nillin Recedes in p53-Dependent Senescence of Tumor Cells and Reappears in Cells Escaping from Senescence	10
Immunometabolism In Brain Aging and Neurodegeneration: Bridging Metabolic Pathways and Immune Responses	10
Metabolic Dysfunction in Idiopathic Intracranial Hypertension: Current Theories and Updates	10
Islet Inflammation and Endocrine Function in Aging - Evaluating the Role of Toll-like receptor 4	9
Mesenchymal Stem Cell-Derived Exosomes Promote Recovery of The Facial Nerve Injury through Regulating Macrophage M1 and M2 Polarization by Targeting the P38 MAPK/NF-Κb Pathway	9
Unveiling the Relation between Cellular Ageing, Epigenetics and Cancer	9
Underlying Mechanisms and Treatment of Cellular Senescence-Induced Biological Barrier Interruption and Related Diseases	9
The α-MSH-MC1R Axis Modulates Sex-Specific Senescence and Inflammation Processes in Human Articular Chondrocytes and Mice Knee Joints	9
Scientific Advancements in Drug Development and Trials for Urothelial Carcinoma: Insights From the 2023 ASCO-GU Cancers Symposium	9
A Framework for an Effective Healthy Longevity Clinic	9
Circadian Rhythm and the Risk of Cardiovascular Diseases: Genetic Evidence	9
Emerging Roles of Skeletal Muscle-Derived Exosomal miRNAs in Metabolic Regulation: A Perspective	9
The Role of Oxidative Stress in Multiple Exercise-Regulated Bone Homeostasis	9
Role and Mechanism of Epigenetic Regulation in the Aging of Germ Cells: Prospects for Targeted Interventions	9
CD16-CD56bright NK Cells: A Protective NK Cell Subset for Progression and Prognosis in Amyotrophic Lateral Sclerosis	9
HFpEF, Aging, Inflammaging, and the Future of Anti-Inflammatory: Therapy in Heart Failure with Preserved Ejection Fraction	9
USP7 Inhibits Osteoclastogenesis via Dual Effects of Attenuating TRAF6/TAK1 Axis and Stimulating STING Signaling	9
Cerebral Small Vessel Disease: Current and Emerging Therapeutic Strategies	9
Differential Effects of Endurance Exercise on Musculoskeletal and Hematopoietic Modulation in Old Mice	9
NeuroD1 Regulated Endothelial Gene Expression to Modulate Transduction of AAV-PHP.eB and Recovery Progress after Ischemic Stroke	9
The Microglial Lactate-Lactylation Axis as a Metabolic-Epigenetic Driver of Alzheimer’s Disease	8
SARS-CoV-2 S Protein Reduces Cytoprotective Defenses and Promotes Human Endothelial Cell Senescence	8
Diagnostic and Therapeutic Potential of Photo-Responsive Nanomaterials in Osteoarthritis	8
The Neglected Sibling: NLRP2 Inflammasome in the Nervous System	8
Impairment of Tricarboxylic Acid Cycle (TCA) Cycle in Alzheimer's Disease: Mechanisms, Implications, and Potential Therapies	8
Hallmarks of Skin Aging: Update	8
ROS-Induced Endothelial Dysfunction in the Pathogenesis of Atherosclerosis	8
Gut Virome and Aging: Phage-Driven Microbial Stability and Immune Modulation	8
Senescence in Aging and Alzheimer’s Disease	8
Predictive Value of Plasma Neurofilament Light Chain for Neurological Outcomes in Patients with Intracerebral Hemorrhage	8
Vascular Aging and Multi-Omic Regulation in Ischemic Stroke: Toward Precision Neurorepair	8
COVID-19 and Cardiovascular Diseases: From Cellular Mechanisms to Clinical Manifestations	8
Hypoxic Conditioning: A Potential Perioperative Strategy to Reduce Abdominal Aortic Occlusion-Related Injury in Mouse Proximal and Distal Organs	8
Biological Aging in Combination with Lifestyle Factors in the Blood-Based Methylome: A Biomarker for Colorectal Cancer Susceptibility in African American Women	8
Risk Factors for Oropharyngeal Dysphagia in Older Adults - Evidence from Consorci Sanitari Del Maresme and Mataró University Hospital, Catalonia, Spain	8
Recent Advances in Aging-Related Diseases: Accelerated Aging, Molecular Mechanisms, Interventions, and Therapies	8
Targeting Cellular Senescence as a Therapeutic Strategy to Attenuate Pulmonary Fibrosis Associated with Metabolic Syndrome	8
Endothelial Senescence in Neurological Diseases	8
Overexpression of RACGAP1 by E2F1 Promotes Neuroendocrine Differentiation of Prostate Cancer by Stabilizing EZH2 Expression	8
Decoding Microglial Polarization and Metabolic Reprogramming in Neurodegenerative Diseases: Implications for Disease Progression and Therapy	8
Mitochondrial Transfer in the Neurovascular Unit, Not Only for Energy Rescue: A Systematic Review	8
Aging Deteriorates Blood Brain Barrier Function and Polarizes Adaptive T Cell Expansion Contributing to Neurocognitive Damage in Experimental Cirrhosis	8
Chondroitin Sulfate Proteoglycans Revisited: Its Mechanism of Generation and Action for Spinal Cord Injury	8
HIV Nef Expression Down-modulated GFAP Expression and Altered Glutamate Uptake and Release and Proliferation in Astrocytes	8
Integrating AI and Causal Genetics to Prioritize Therapeutic Targets for Aging and Age-Related Diseases	8
Metabolic-Inflammatory Syndrome: Decoding the Metabolic-Immune Axis for Precision Intervention	8
From Insight to Eyesight: Unveiling the Secrets of the Insulin-Like Growth Factor Axis in Retinal Health	7
Cognitive Impairment after Aneurysmal Subarachnoid Hemorrhage: Temporal Patterns and Electrophysiological Risk Stratification	7
Immunosenescence in Sepsis: Molecular Mechanisms and Potential Therapeutic Targets	7
Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia	7
Alzheimer Disease Pathology and Neurodegeneration in Midlife Obesity: A Pilot Study	7
Rare Clinical Presentation of Postmenopausal Endometriosis: A New Perspective	7
Senolytic Treatment Improve Small Intestine Regeneration in Aging	7
Role of Crosstalk between Glial Cells and Immune Cells in Blood-Brain Barrier Damage and Protection after Acute Ischemic Stroke	7
Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation Strategies	7
Targeting Mitochondrial Integrity as a New Senolytic Strategy	7
Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies	7
The Q4-Mood Framework: A Stratified Movement Intervention Model for Late-Life Depression	7
Perceived Hypoacusis and Loneliness: A Longitudinal Between- and Within-Individual Association in Mexican Older Adults	7
Aging, Cellular Senescence, and Glaucoma	7
Emerging Perspectives in Anti-aging Treatments Using Anti-Fibrotic Strategies	7
Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging	7
Brain Iron Dyshomeostasis and Ferroptosis in Alzheimer’s Disease Pathophysiology: Two Faces of the Same Coin	7
m6A Reader HNRNPC Facilitates Adipogenesis by Regulating Cytoskeletal Remodeling through Enhanced Lcp1 mRNA Stability	7
Potential Risk to Brain Health after Surgical Interventions: Biomarkers to Predict the Occurrence of Cognitive Decline	7
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo	7