Aging and Disease

Papers
(The H4-Index of Aging and Disease is 36. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Burn Injuries Accelerate Biological Aging and Increase the Epigenetically Inferred Risk of Mortality and Frailty108
Revisiting the Role of Mitochondrial DNA Mutations in Aging: Bridging Theoretical Expectations with Empirical Observations107
Metabolic Dysregulation in Parkinson’s Disease: Non-Oxidative Phosphorylation and Its Role in Brain Energy Metabolism103
Aligning Intrinsic Capacity and Geroscience: Linking Function with Biology79
Correlations between Aging, Telomeres, and Natural Compounds78
Vascular Contributions to Healthy Aging and Dementia72
The HLA-B*57:01 Haplotype, Genetic Key Linking Innate Immunity and Longevity68
The Roles of T cells in Immune Checkpoint Inhibitor-Induced Arthritis64
Neuropsychological Profiles in Genetic Frontotemporal Dementia: A Meta-Analysis and Systematic Review59
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies57
Axonal Energy Crisis and Calcium Phosphate Dysregulation as Pathogenesis of Optic Disc Drusen55
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung53
Quantum Sensing for Precision Organ Aging Assessment52
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies52
Cross-Tissue Proteomic Mendelian Randomization Identifies Therapeutic Targets for Vascular Dementia50
Lysine Malonylation and Its Links to Metabolism and Diseases48
Astrocyte-Microglia Crosstalk: A Novel Target for the Treatment of Migraine48
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization47
Updates in Intravenous Thrombolysis Treatment for Acute Ischemic Stroke in Asian Populations45
Vascular Aging and Atherosclerosis: A Perspective on Aging45
KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging45
Retinal Pigment Epithelium Phagocytosis and Retinal Degenerative Diseases45
A Systematic Review of Intervention Trials Utilizing Biomarkers Among Informal Caregivers of People with Alzheimer's Disease & Related Dementias44
Exploiting the Fractionation of Stable Isotopes in Biochemical Processes for Medical Diagnosis: A Narrative Review44
Early Risk Prediction Model for Stroke-Heart Syndrome Following Endovascular Therapy43
Role of AMPK and Sirtuins in Aging Heart: Basic and Translational Aspects43
Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis43
Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the LmnaG609G/G609G Mouse Model of Progeria41
Unmet Medication Needs and the Association with Mortality in Older Adults: Equality-Oriented Monitoring toward Universal Health Coverage41
Apolipoprotein CII: Cornerstone of Pathophysiological Interplay in Aortic Stenosis and type 2 Diabetes Mellitus40
Age-, sex-, and ancestry-specific prevalence of hearing loss in UK Biobank and All of Us Research Program40
Aβ Deposition in Extracellular Space Disrupts Glial-Neuron Communication and Triggers Alzheimer's Disease39
VCAM-1 in Cognitive Impairment: Mechanisms, Biomarker Potential, and Therapeutic Targeting39
Stroke-Induced Retinal Dysfunction: Mechanisms, Diagnostics, and Future Directions37
Beyond Amyloid: Rethinking the Foundations of Alzheimer’s Disease Pathogenesis and Therapy36
Immunosenescence: Shaping the Hematological Narrative in the Era of Aging36
Telomeres: Dysfunction, Maintenance, Aging and Cancer36
0.15314984321594