OOIR: Observatory of International Research

Papers

(The H4-Index of Aging and Disease is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Effect of COVID-19 on Geriatric Medical Services in China	223
Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant Response	105
Protein Synthesis Errors and Longevity: A Lesson from a Single Amino Acid Mutation Study	99
Pip5k1c Loss in Chondrocytes Causes Spontaneous Osteoarthritic Lesions in Aged Mice	71
KRT5⁺/p63⁺ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging	68
Broadening Horizons: Exploring mtDAMPs as a Mechanism and Potential Intervention Target in Cardiovascular Diseases	66
Vascular Aging and Atherosclerosis: A Perspective on Aging	61
Scoping Review of Technological Solutions for Community Dwelling Older Adults and Implications for Instrumental Activities of Daily Living	57
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization	56
Advancing Hydrocephalus Management: Pathogenesis Insights, Therapeutic Innovations, and Emerging Challenges	54
Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells	51
Atherosclerosis: The Involvement of Immunity, Cytokines and Cells in Pathogenesis, and Potential Novel Therapeutics	50
A Connection Between the Gut Microbiome and Epigenetic Modification in Age-Related Cancer: A Narrative Review	50
Current Understanding of Marginal Grafts in Liver Transplantation	43
Cellular Senescence in the Regenerative Niche Hampers Skeletal Muscle Repair	42
The Role of Myeloid-Derived Suppressor Cells in Multiple Sclerosis and Its Animal Model	41
Inhibiting MicroRNA-141-3p Improves Musculoskeletal Health in Aged Mice	41
Atrial Fibrillation Underlies Cardiomyocyte Senescence and Contributes to Deleterious Atrial Remodeling during Disease Progression	41
Neuron-targeted Knockout of APE1 Forces Premature Cognitive Impairment and Synaptic Dysfunction in Adult Mice	41
Recent Neurotherapeutic Strategies to Promote Healthy Brain Aging: Are we there yet?	39
Higher Functional Connectivity of Ventral Attention and Visual Network to Maintain Cognitive Performance in White Matter Hyperintensity	39
Aging Gut Microbiome in Healthy and Unhealthy Aging	38
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies	38
Inflammatory Markers Associated with Physical Frailty and Cognitive Impairment	37
Revisiting the Role of Mitochondrial DNA Mutations in Aging: Bridging Theoretical Expectations with Empirical Observations	37

Exploiting the Fractionation of Stable Isotopes in Biochemical Processes for Medical Diagnosis: A Narrative Review	37
Unveiling the Therapeutic Promise of Epigenetics in Vascular Cognitive Impairment and Vascular Dementia	35
Upregulation of Na/H Exchanger in Astrogliosis and Early Alzheimer’s Disease Pathogenesis	34
Erratum to “NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice	31
A Population-Based Scoring System to Assess the Impact of Individual Risk Factors on Vascular Health	31
Shedding Light on the Interaction Between Rif1 and Telomeres in Ovarian Cancer	30