Aging and Disease

Papers
(The H4-Index of Aging and Disease is 38. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Is the β Common Receptor the Key Molecule for the Protective Effect of Erythropoietin?324
Protein Synthesis Errors and Longevity: A Lesson from a Single Amino Acid Mutation Study129
Axonal Energy Crisis and Calcium Phosphate Dysregulation as Pathogenesis of Optic Disc Drusen121
Burn Injuries Accelerate Biological Aging and Increase the Epigenetically Inferred Risk of Mortality and Frailty119
Updates in Intravenous Thrombolysis Treatment for Acute Ischemic Stroke in Asian Populations104
Revisiting the Role of Mitochondrial DNA Mutations in Aging: Bridging Theoretical Expectations with Empirical Observations90
Exploiting the Fractionation of Stable Isotopes in Biochemical Processes for Medical Diagnosis: A Narrative Review86
Vascular Contributions to Healthy Aging and Dementia76
The HLA-B*57:01 Haplotype, Genetic Key Linking Innate Immunity and Longevity75
Retinal Pigment Epithelium Phagocytosis and Retinal Degenerative Diseases74
Neuropsychological Profiles in Genetic Frontotemporal Dementia: A Meta-Analysis and Systematic Review70
Targeting Cellular Senescence in Aging and Age-Related Diseases: Challenges, Considerations, and the Emerging Role of Senolytic and Senomorphic Therapies70
Astrocyte-Microglia Crosstalk: A Novel Target for the Treatment of Migraine69
The Roles of T cells in Immune Checkpoint Inhibitor-Induced Arthritis62
EP3 Receptor Deficiency Improves Vascular Remodeling and Cognitive Impairment in Cerebral Small Vessel Disease57
Metabolic Dysregulation in Parkinson’s Disease: Non-Oxidative Phosphorylation and Its Role in Brain Energy Metabolism57
KRT5+/p63+ Stem Cells Undergo Senescence in the Human Lung with Pathological Aging56
Lysine Malonylation and Its Links to Metabolism and Diseases55
Neuronal Intranuclear Inclusion Disease with NOTCH2NLC GGC Repeat Expansion: A Systematic Review and Challenges of Phenotypic Characterization55
Correlations between Aging, Telomeres, and Natural Compounds54
Aging-Related Sarcopenia: Metabolic Characteristics and Therapeutic Strategies51
Vascular Aging and Atherosclerosis: A Perspective on Aging49
The Role of the Redox Enzyme p66Shc in Biological Aging of the Lung48
Neuroprotective Mechanisms of Puerarin in Central Nervous System Diseases: Update48
A Systematic Review of Intervention Trials Utilizing Biomarkers Among Informal Caregivers of People with Alzheimer's Disease & Related Dementias48
Neuroinflammation as a Link in Parkinson’s and Alzheimer’s Diseases: A Systematic Review and Meta-Analysis48
Perspectives on Movement and Eating Behaviours in Brazilian Elderly: An Analysis of Clusters Associated with Disease Outcomes47
Telomeres: Dysfunction, Maintenance, Aging and Cancer46
Role of AMPK and Sirtuins in Aging Heart: Basic and Translational Aspects46
Exosomal Proteomics: Unveiling Novel Insights into Lung Cancer44
EchoAGE: Echocardiography-based Neural Network Model Forecasting Heart Biological Age42
Early Risk Prediction Model for Stroke-Heart Syndrome Following Endovascular Therapy42
Unmet Medication Needs and the Association with Mortality in Older Adults: Equality-Oriented Monitoring toward Universal Health Coverage41
VCAM-1 in Cognitive Impairment: Mechanisms, Biomarker Potential, and Therapeutic Targeting41
Spinal Cord Injury and Ageing: The Role of Chronic Neuroinflammation40
Citicoline for Supporting Memory in Aging Humans39
Microcirculation Dysfunction in Subacute Stroke: The Role of Delayed Capillary Pericyte Loss39
Role of Serotonylation and SERT Posttranslational Modifications in Alzheimer's Disease Pathogenesis39
Normal Bone Matrix Mineralization but Altered Growth Plate Morphology in the LmnaG609G/G609G Mouse Model of Progeria38
Age-, sex-, and ancestry-specific prevalence of hearing loss in UK Biobank and All of Us Research Program38
Apolipoprotein CII: Cornerstone of Pathophysiological Interplay in Aortic Stenosis and type 2 Diabetes Mellitus38
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