Virulence

Article	Citations
Letter to the editor (response to Vajro and colleagues)	188
Streptococcus pyogenes emm 98.1 variants activate inflammatory caspases in human neutrophils	141
Comparison of Omicron and respiratory virus infections in pediatric liver transplantation: Impact of perioperative identification status	127
Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein	122
A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner	108
Adult duck fecal microbiota transplantation alleviates short beak and dwarfism syndrome in ducklings by inhibiting Th17 cell differentiation	104
Correction	100
Genomic characterization of Actinobacillus pleuropneumoniae serovars 5, 8, and 15 strains from diseased pigs in eastern Chinese provinces	92
Successful cell culture isolation and experimental pathogenicity evaluation of porcine bocavirus G3	88
Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis	85
EefR mutations drive sanguinarine resistance by activating cryptic multidrug efflux pumps in AcrB-Null Escherichia coli	79
Characterization of the intrahepatic microbiome in patients with HBV-related end-stage liver disease	76
Study of the relationships among known virulence genes, coccoid transformation and cytotoxicity of Helicobacter pylori in different clinical diseases	72
STA regulates succinylated AflM triggered by SCS to contribute to aflatoxin biosynthesis through the Ach1	70
MGF100 but not MGF300 family is a potential multigene-deleted target for ASFV attenuation and live attenuated vaccine development	64
Herpesviruses and autophagy: An intracellular conflict	64
Oropouche virus: Understanding “sloth fever” disease dynamics and novel intervention strategies against this emerging neglected tropical disease	62
Anti-HBc IgM associates with acute flare and HBeAg/HBsAg loss in chronic hepatitis B patients with acute exacerbation	59
Pathogenesis and virulence of Heartland virus	58
Pathogenicity and virulence of henipaviruses	57
Prevalence of bovine endometritis, virulence mechanisms of Escherichia coli , and current therapeutic strategies: A review	56
Pathogenicity and virulence of influenza	53
The two-component system histidine kinase LiaS contributes to the stress resistance and virulence of zoonotic Listeria monocytogenes	51
Pathogenicity and virulence of O’nyong-nyong virus: A less studied Togaviridae with pandemic potential	49
Predicting the evolutionary and epidemiological dynamics of SARS-CoV-2 in South Africa	47

Pathogenicity and virulence of Candida auris	46
A new gene family (BAPs) of Cotesia bracovirus induces apoptosis of host hemocytes	46
Host cell transcriptomic response to the multidrug-resistant Mycobacterium tuberculosis clonal outbreak Beijing strain reveals its pathogenic features	42
Acinetobacter baumannii : Mechanisms of antibiotic resistance, quorum sensing regulation, and current therapeutic strategies	42
Molecular epidemiology of Nakaseomyces glabrata associated with vulvovaginal candidiasis revealed high genetic variability and the presence of novel geno	42
Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations	41
Protection acquired upon intraperitoneal group a Streptococcus immunization is independent of concurrent adaptive immune responses but relies on macropha	41
Carbon source-driven downregulation of the sRNA AmiL enhances Pseudomonas aeruginosa virulence during acute lung infection	40
DDX17 and viral infection	39
Antibacterial efficacy and mechanism of the novel antimicrobial peptide lachnospirin-1 against Acinetobacter baumannii	39
Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid	38
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and	38
Ctr9 promotes virulence of Candida albicans by regulating methionine metabolism	36
Prevalence and clinical significance of HBeAg-positive chronic hepatitis B patients with and without anti-HBe antibody	35
Inhibitory effects of a maleimide compound on the virulence factors of Candida albicans	35
Comparative genomic and virulence analyses of a novel sequence type 420 Streptococcus equi subspecies zooepidemicus	34
Genetic insights into the interaction between chronic hepatitis B virus infection and metabolic syndrome	34
Comparative transcriptomic analysis reveal genes involved in the pathogenicity increase of Streptococcus suis epidemic strains	33
Statistical analysis supports UTR (untranslated region) deletion theory in SARS-CoV-2	32
Chikungunya virus nsP2: Insights into viral replication, pathogenesis, and therapeutic targeting	32
Nucleotide variations in 3’ untranslated region contribute to the enhanced virulence and replication efficiency of reemerging Japanese encephalitis virus genotype V	31
Streptococcus suis serotype 5: Emerging zoonotic threat with distinct genomic heterogeneity	30
Galleria mellonella proteomic response to infection with Streptococcus pyogenes	29
Biofilm-mediated antibiotic tolerance in bacterial pathogens: Integrated molecular networks and novel therapeutic avenues	27
Type 2 hypersensitivity disorders, including systemic lupus erythematosus, Sjögren’s syndrome, Graves’ disease, myasthenia gravis, immune thrombocytopenia, autoimmune hemolytic anemia, dermatomyositis	27
Small regulatory RNAs mediated regulation of virulence and host–pathogen interaction in the Gram-negative ESKAPE pathogens	27
Pathogenicity and virulence of Francisella tularensis	27
Stenotrophomonas maltophilia of clinical origin display higher temperature tolerance comparing with environmental isolates	27
Autophagy-driven modulation of stem cell dynamics in Helicobacter pylori -induced gastric diseases in mice	26
Langya henipavirus: Is it a potential cause for public health concern?	26
Senecavirus A non-structural protein 2C and 3A-specific T cell-epitopes promote inactivated vaccine efficacy in pigs via synergistic cellular and humoral immunity	25
LeuO fine-tunes the virulence attributable to Salmonella pathogenicity island-2 via repressing ssrA transc	25
Evolution of Mycobacterium abscessus in the human lung: Cumulative mutations and genomic rearrangement of porin genes in patient isolates	25
Porcine cGAS-STING signalling induced apoptosis negatively regulates STING downstream IFN response and autophagy via different mechanisms	24
A promising endeavor against human cytomegalovirus: Predominant epitopes-based recombinant subunit vaccine RH Ec IE1/pp65/pp150	24
QX-type infectious bronchitis virus infection in roosters can seriously injure the reproductive system and cause sex hormone secretion disorder	24
Changes in gene expression levels caused by H3K9me3/H3K9ac modifications are associated with BmCPV infection in Bombyx mori	24
Fluorescence-based biosensors for West Nile virus detection	24
Carnosol attenuates Acinetobacter baumannii virulence by interfering with indole-mediated quorum sensing	23
Identification of miR-29a as a novel biomarker for lumpy skin disease virus exposure in cattle	23
The dual pathogenic role of IL-24 in sepsis: Coupling bacterial dissemination with inflammatory amplification as a therapeutic target	23
Hemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK	23
Alpha1-antitrypsin impacts innate host–pathogen interactions with Candida albicans by stimulating fungal filamentation	22
Synergistic host-parasitoid antimicrobial peptide interactions ensure the survival of parasitized hosts	22
Genomic insights into multidrug-resistant bacteria: Emergence of mcr-1.1 in Escherichia coli ,	22
Genomic epidemiology, evolution, and transmission dynamics of porcine sapelovirus associated with diarrheic piglets	22
An updated review of HSV-1 infection-associated diseases and treatment, vaccine development, and vector therapy application	21
Innovative use of gram-positive enhancer matrix particles and affinity peptides in a vaccine against Coxsackievirus B3	21
Investigating the differential microRNAs expression in young and aged Drosophila melanogaster following Flock House Virus infection	21
The multiple roles of viral 3D pol protein in picornavirus infections	21

Pathogenicity and virulence of Streptococcus suis serotype 2: Emerging insights and persistent knowledge gaps	21
Proteomic characterization of Aspergillus fumigatus – host interactions using the ex-vivo pig lung (EVPL)	21
Detection of Clostridium sporogenes in a Roman-era cattle mass grave at Vilauba	20
Methyltransferase K-D-K-E motif influences the intercellular transmission of Newcastle disease virus	19
NagZ modulates the virulence of E. cloacae by acting through the gene of unknown function, ECL_03795	19
Single-cell landscape of piglet lung response with Actinobacillus pleuropneumoniae	19
Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens	19
Monkeypox virus replication and host response in vaginal and ectocervical epithelial cells	18
Microsporidia keratoconjunctivitis identified as an emerging zoonotic threat from pet parrots: Clinical and metagenomic next-generation sequencing evidence	18
A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response	18
Emerging West African Genotype Chikungunya Virus in Mosquito Virome	18
Genomic characterization, transcriptome analysis, and pathogenicity of the Nipah virus (Indian isolate)	18
Neutralizing epitope mapping for deltacoronavirus receptor-binding domain and seroepidemiological survey across different animal species	18
Pathogenicity and virulence of Brucella : Strategies for metabolic adaptation and immune evasion	18
Mechanisms of Talaromyces marneffei induced CNS injury: Synergistic roles of tauopathy, pyroptosis, and microglial inflammation	18
The characteristics of TCR CDR3 repertoire in COVID-19 patients and SARS-CoV-2 vaccine recipients	18
Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A	18
Pathogenicity and virulence of monkeypox at the human-animal-ecology interface	17
Inhibitors of GapN-dependent NADPH supply as potential lead compounds for novel therapeutics against Streptococcus pyogenes	17
Cryptosporidium parvum CpARO marks rhoptry envelope remnants associated with feeder organelle formation	17
Ohmyungsamycin promotes M1-like inflammatory responses to enhance host defence against Mycobacteroides abscessus infections	17
Host-Orf virus interactions: A comprehensive review of pathogenesis and immune evasion mechanisms	17
Protective efficacy of a novel recombinant influenza virus carrying partial human metapneumovirus F protein epitopes	17
Analysis of HIV-1 subtypes and drug resistance mutations in people who inject drugs in Aizawl and nearby districts of Mizoram, India	17
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions	17
AoVps18 regulates sporulation, trap morphogenesis, and nematode predation by modulating vacuole assembly and attractant synthesis in Arthrobotrys oligospora	16
The multifaceted interactions between Newcastle disease virus proteins and host proteins: a systematic review	16
Effects of Isaria cateniannulata on the colonization process and enzyme activity of Fagopyrum tataricum se	16
Genome-wide Identification of conditionally essential genes supporting Streptococcus suis growth in serum and cerebrospinal fluid	16
The molybdate transport protein ModA regulates nitrate reductase activity to increase the intestinal colonization and extraintestinal dissemination of Klebsiella pneumoniae	16
Pathogenicity and Virulence of Fusarium oxysporum f. sp. vasinfectum Race 4: Understanding an Emerging Thr	16
Iron depletion has different consequences on the growth and survival of Toxoplasma gondii strains	16
Identification of fidelity-determined residues of Porcine reproductive and respiratory syndrome virus through structural alignment	15
Immunoevasion strategies for African swine fever virus: Modulation of antigen presentation pathways	15
Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model	15
Hepatitis B core-related antigen serum levels may be a predictor of acute flare of chronic hepatitis B among pregnant women in the immune-tolerant phase of chronic HBV infection after short-course ant	15
Characterization and genomic insights into bacteriophages Kpph1 and Kpph9 against hypervirulent carbapenem-resistant Klebsiella pneumoniae	15
Peptostreptococcus Anaerobius enhances dextran sulfate sodium-induced colitis by promoting nf-κB-NLRP3-Dependent macrophage pyroptosis	15
Bactericidal and anti-quorum sensing activity of repurposing drug Visomitin against Staphylococcus aureus	15
The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis	15
Cleavage of cellular substrate porcine gasdermin D by porcine torovirus 3C-like protease induces pyroptosis	15
Microbiological control for mosquito larvae: Current progress and applications	15
Chlamydia psittaci : A zoonotic pathogen causing avian chlamydiosis and psittacosis	15
Roles and mechanisms of gapA and gap -encoded proteins in cronobacter sakazakii	14
Porcine reproductive and respiratory syndrome virus infects the reproductive system of male piglets and impairs development of the blood–testis barrier	14
Correction	14
Wzi modulates immune evasion of hypervirulent Klebsiella pneumoniae in a CPS-dependent and independent manner	14
Analyses of receptor binding specificity of highly pathogenic avian influenza A (H5N1) viruses isolated from felines in South Korea, 2023	14
Tobramycin-resistant small colony variant mutant of Salmonella enterica serovar Typhimurium shows collateral sensitivity to nitrofurantoin	14
High frequency of CD8 escape mutations in elite controllers as new obstacle for HIV cure	14
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess	13
Alongshan virus: An emerging arboviral challenge in regional health security	13
Intracellular survival of Staphylococcus aureus in macrophages during osteomyelitis	13
Decarboxylase mediated oxalic acid metabolism is important to antioxidation and detoxification rather than pathogenicity in Magnaporthe oryzae	13
Recent Discoveries of Novel Mammarenaviruses Infecting Humans and Other Mammals in Asia and Southeast Asia	13
Cordycepin suppresses growth and virulence of Magnaporthe oryzae via mitochondrial function and carbonic anhydrase-associated nitrogen metabolism	13
Multifaceted effects of galU deletion on phenotype and virulence of Pseudomonas aeruginosa in vitro and	13
Sucrose non-fermenting protein kinase gene UvSnf1 is required for virulence in Ustilaginoidea virens	13
A shared mechanism of multidrug resistance in laboratory-evolved uropathogenic Escherichia coli	13
Epithelial cell invasion by salmonella typhimurium induces modulation of genes controlled by aryl hydrocarbon receptor signaling and involved in extracellular matrix bio	13
Emerging threat of Oropouche virus: Clinical features, experimental models, and virulence	13
Interplay of Mycobacterium abscessus and Pseudomonas aeruginosa in experimental models of coinfection: Bio	13
The role of glutathione for oxidative stress and pathogenicity of Streptococcus suis	13
Ferroptosis and macrophage efferocytosis in periodontitis: Biological insights and therapeutic advances	12
Helicobacter pylori East Asian type CagA hijacks more SHIP2 by its EPIYA-D motif to potentiate the oncogenicity	12
Novel Taiwan-I-type infectious bronchitis virus: First evidence of testicular atrophy and efficacious protection with strain-matched oil-emulsified inactivated vaccine	12
ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication	12
The Hog1-Nmd5 signaling pathway regulates asexual development, lipid metabolism, stress response, trap morphogenesis, and secondary metabolism of Arthrobotrys oligospora	12
Hijacking and subversion of macrophage antiviral functions by viruses	12
Novel avian metapneumovirus subtype C variant is a newly emerged pathogen causing hydrosalpinx fluid syndrome in Sheldrake ducks in China	12
Physiological role of bicarbonate in microbes: A double-edged sword?	12
Synergetic attenuated inflammatory response and increased apoptosis confer high pathogenicity of Acinetobacter baumannii	12
The F 1 F o -ATP synthase α subunit of Candida albicans induces inflammatory responses by controlli	12
Balancing harm and harmony: Evolutionary dynamics between gut microbiota-derived flagellin and TLR5-mediated host immunity and metabolism	12
Intratumorally specific microbial-derived lipopolysaccharide contributes to non-small cell lung cancer progression	12
Porphyromonas gulae and canine periodontal disease: Current understanding and future directions	12
Foot-and-mouth disease virus 3C protease as virulence determinant plays multiple roles in cleaving viral polyprotein and host factors	12
Pangenomic analysis reveals metabolic adaptation of Haemophilus parainfluenzae to the urogenital tract	12
Pathogenicity and virulence of Borrelia burgdorferi	12
Comparative transcriptome combined with morphophysiological analyses revealed the molecular mechanism underlying Tetrahymena thermophila predation-induced antiphage defense in Aeromonas hydr	12

Circulated echovirus 18 strains in Guangdong Province and worldwide: A novel perspective on genetic diversity and recombination patterns	11
Impact of antiviral treatment and initiation time on mother-to-child transmission in pregnant women with extremely high HBV DNA loads	11
Emerging infection and nosocomial transmission of carbapenem-resistant Klebsiella pneumoniae harboring bla	11
SARS-CoV-2 versus other minor viral infection on kidney injury in asymptomatic and mildly symptomatic patients	11
Exogenous NADH promotes the bactericidal effect of aminoglycoside antibiotics against Edwardsiella tarda	11
A human intestinal organoid derived from fetal human colon cells model for studying enteroviral pathogenesis	11
Preliminary assessment of the therapeutic potential of staphylococcal enterotoxin-like W via biological activity and TCR binding sites analysis	11
Ixchiq (VLA1553): The first FDA-approved vaccine to prevent disease caused by Chikungunya virus infection	11
The CueR-regulated transporters CopA and CusFABC coordinate copper detoxification in Vibrio parahaemolyticus	11
Exogenous proline promotes serum killing of Klebsiella pneumoniae	11
UvVelC is important for conidiation and pathogenicity in the rice false smut pathogen Ustilaginoidea virens	11
The “oral-gut axis” transmission of microorganisms in colorectal cancer: Insights from Peptostreptococcus’ perspective	11
Loss and gain of ceftazidime-avibactam susceptibility in a non-carbapenemase-producing K1-ST23 hypervirulent Klebsiella pneumoniae	11
Emergence of Staphylococcus argenteus in pediatrics: Molecular insights from a hospital in East China	11
Screening optimal DC-targeting peptide to enhance the immune efficacy of recombinant Lactobacillus expressing RHDV VP60	11
It’s time to act: Understanding and combating Vibrio vulnificus	11
Exploring the role of multi-pathogen infections in Alzheimer’s disease: A case–control study	11
HIF-1α interacting with miR-2013-3p regulates pathogen-induced energy production changes via targeting glutamate dehydrogenase in the sea urchin Strongylocentrotus intermedius	11
Tilmicosin inhibits the infections of currently prevalent porcine reproductive and respiratory syndrome viruses via the downregulation of CD163 expression	10
A distinct variant of the SzM protein of Streptococcus equi subsp. zooepidemicus recruits C1q independent of IgG binding and inhibits acti	10
Autophagy and ubiquitination in important swine viral infections: Host defense and viral antagonism	10
Integrated transcriptome and metabolome reveal Mycoplasma hyopneumoniae -induced lipid accumulation, inflammation, oxidative stress, and energy imbalance	10
H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage	10
Role of riboflavin biosynthesis gene duplication and transporter in Aeromonas salmonicida virulence in marine teleost fish	10
Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease	10
Recent global outbreaks of highly pathogenic and low-pathogenicity avian influenza A virus infections	10
Liver–joint axis: Hepatitis B virus as a contributor to rheumatoid arthritis pathogenesis	10
Annexin A2: the missing piece in the puzzle of pathogen-induced damage	10
Multi-omics profiling of acute Pseudomonas aeruginosa pneumonia unmasks conventional NK cell depletion and stage-specific therapeutic targets	10
Isolation and characterization of a red panda amdoparvovirus causing fatal respiratory disease: Identification of VP2-S447 as a key determinant of acute lung injury	10
Disruption of CmHmgr1 triggers apoptosis and causes defects in growth, conidiogenesis, and mycoparasitism of Coniothyrium minitans	10
Nomogram for evaluating obvious liver inflammation in treatment-naïve HBeAg positive chronic hepatitis B virus infection patients with normal ALT	10
Xylose utilization promotes Salmonella replication within macrophages and systemic infection in mice	10
Malassezia globosa lipidome: The dynamics of uptake and secreted lipids	10
A porcine model of chronic hepatitis E virus (HEV) infection identifies male reproductive glands as sites of viral persistence	10
A novel aquaporin Aagp contributes to Streptococcus suis H 2 O 2 efflux and virulence	10
Culture breakthrough enables goose circovirus (GoCV) isolation and pathogenic gosling modeling to uncover the association between viral infection and vaccine failure	10
The urinary microbiome distinguishes symptomatic urinary tract infection from asymptomatic older adult patients presenting to the emergency department	10
Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants	10
Correction	10
Thymosin α1-induced secretion of the IL-15/RA complex by THP-1-derived dendritic cells restrains HIV latency in vitro	10
Pathogenicity and virulence of Chlamydia trachomatis : Insights into host interactions, immune evasion, and intracellular survival	9
Correction	9
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration	9
Comprehensive diagnostic approaches to feline toxoplasmosis: Bridging traditional methods and emerging technologies	9
Klebsiella pneumoniae derived outer membrane vesicles mediated bacterial virulence, antibiotic resistance, host immune responses and clinical applications	9
Mannan is a context-dependent shield that modifies virulence in Nakaseomyces glabratus	9
Pathogenicity and virulence of Phytophthora infestans : The ever-evolving threat to food security and its sustainable management strategies	9
African swine fever virus protein p17 promotes mitophagy by facilitating the interaction of SQSTM1 with TOMM70	9
Humoral responses to multiple SARS-CoV-2 variants after two doses of vaccine in kidney transplant patients	9
LncRNA transcriptome analysis of rainbow trout ( Oncorhynchus mykiss ) skin infected with IHNV reveals that lncRNA SARL/miR-205-z/	9
Distinctive function of Tetraspanins: Implication in viral infections	9
Conserved deletion of two consecutive glycine residues in the 100K protein is a critical determinant of FAdV-11 pathogenicity	9
Pathogenicity and virulence of Helicobacter pylori : A paradigm of chronic infection	9
A systematic survey of type I secretion systems and their substrate proteins in Salmonella	9
Protoporphyrin IX targets viral spike glycoproteins to inactivate Akabane virus	9
Adjuvants for Helicobacter pylori vaccines: Outer membrane vesicles provide an alternative strategy	9
Pathogenicity and Virulence of Coxiella burnetii: Focus on Q fever	9
Iron metabolism contributes to virulence by enhancing serum resistance in the emerging high-risk clone ST15 CRKP	9
Time to positivity of Klebsiella pneumoniae in blood cultures as prognostic marker in patients with intra-abdominal infection: A retrospective study	9
Staphylococcus aureus planktonic but not biofilm environment induces an IFN-β macrophage immune response via the STING/IRF3 pathway	9
Honey-derived Paenibacillus spp. with potential to affect bee brood development in Apis mellifera : Are th	9
Emergence and molecular evolution of carbapenem-resistant hypervirulent ST23 Klebsiella pneumoniae : The superbug phenomenon in China	9
Deciphering the immunomodulatory cross-talk: Bacterial extracellular vesicles in gut homeostasis	9
Lactic acid in the vaginal milieu modulates the Candida -host interaction	9
Grass carp catalase inhibits GCRV replication through ROS scavenging-mediated immune suppression and autophagy	9
Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion	9
Pathogenicity and virulence of African swine fever virus	9
The cell-type-specific roles of Toll-like receptors in herpes simplex virus infection and pathogenesis	9
Blood virome profiling reveals subtype-specific viral signatures and reduced diversity in non-Hodgkin lymphoma	9