OOIR: Observatory of International Research

Papers

(The TQCC of Virulence is 12. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Pathogenicity and virulence of Staphylococcus aureus	613
Pathogenesis and virulence of Candida albicans	169
COVID-19 evolution during the pandemic – Implications of new SARS-CoV-2 variants on disease control and public health policies	138
Pathogenesis and virulence of herpes simplex virus	137
Pathogenicity and virulence of Clostridium perfringens	113
Pathogenicity and virulence ofListeria monocytogenes: A trip from environmental to medical microbiology	80
Immune dysregulation and system pathology in COVID-19	77
Seroprevalence of SARS-CoV-2 (COVID-19) exposure in pet cats and dogs in Minnesota, USA	69
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage	68
Pathogenicity and Virulence ofLegionella: Intracellular replication and host response	66
Pathogenicity and virulence of the liver flukesFasciola hepaticaandFasciolaGiganticathat cause the zoonosis Fasciolosis	61
Pathogenicity and virulence of Marburg virus	57
Pathogenicity and virulence of Mycobacterium tuberculosis	49
Pathogenesis and virulence of flavivirus infections	49
The pathogenicity and virulence of Toxoplasma gondii	47
Pathogenicity and virulence of Clostridioides difficile	46
An Organ System-Based Synopsis ofPseudomonas aeruginosaVirulence	45
Therapeutic implications of C. albicans-S. aureus mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection	43
Glycosylation of viral proteins: Implication in virus–host interaction and virulence	42
Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals	39
Antimicrobial photodynamic therapy (aPDT) for biofilm treatments. Possible synergy between aPDT and pulsed electric fields	37
Pathogenicity & virulence ofMycoplasma hyopneumoniae	37
Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus	36
Genetic diversity and evolution of the virulence plasmids encoding aerobactin and salmochelin in Klebsiella pneumoniae	36
Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora	35

Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions	34
Paeoniflorin reduce luxS/AI-2 system-controlled biofilm formation and virulence in Streptococcus suis	34
The hypermucoviscosity of hypervirulent K. pneumoniae confers the ability to evade neutrophil-mediated phagocytosis	34
Virulence ofCandida aurisfrom different clinical origins inCaenorhabditis elegansandGalleria mellonellahost models	33
Pathogenicity and virulence of Hepatitis B virus	33
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris	33
AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection	33
Infection strategies of mycoplasmas: Unraveling the panoply of virulence factors	33
The pathogenesis and virulence of enterovirus-D68 infection	32
Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host	32
Pathogenicity and virulence ofStreptococcus pneumoniae: Cutting to the chase on proteases	32
Distribution and antifungal susceptibility pattern ofCandidaspecies from mainland China: A systematic analysis	32
A serious skin virus epidemic sweeping through the Indian subcontinent is a threat to the livelihood of farmers	32
Persistent low-Level viremia in persons living with HIV undertreatment: An unresolved status	30
Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study	29
A clubroot pathogen effector targets cruciferous cysteine proteases to suppress plant immunity	29
The battle for autophagy between host and influenza A virus	29
Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity	29
Host Defence RNases as Antiviral Agents against Enveloped Single Stranded RNA Viruses	28
YjbH regulates virulence genes expression and oxidative stress resistance in Staphylococcus aureus	28
Synergy of alanine and gentamicin to reduce nitric oxide for elevating killing efficacy to antibiotic-resistant Vibrio alginolyticus	28
Pathogenicity and virulence of Entamoeba histolytica , the agent of amoebiasis	27
Pathogenicity and virulence of influenza	27
Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4	26
Pathogenicity and virulence of hepatitis A virus	26
Versatile lifestyles of Edwardsiella: Free-living, pathogen, and core bacterium of the aquatic resistome	26
The African swine fever virus protease pS273R inhibits DNA sensing cGAS-STING pathway by targeting IKKε	26
Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication	25
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2	25
Pathogenicity and virulence of West Nile virus revisited eight decades after its first isolation	24
Shewanellainfection in humans: Epidemiology, clinical features and pathogenicity	24
Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model	23
Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins	23
Pathogenicity and virulence of Mycobacterium leprae	23
Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A	23
Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.	23
Pathogenicity and virulence of Clostridium botulinum	23
Pathogenicity and virulence of Aspergillus fumigatus	22
MSS2 maintains mitochondrial function and is required for chitosan resistance, invasive growth, biofilm formation and virulence in Candida albicans	22
Importance of twitching and surface-associated motility in the virulence of Acinetobacter baumannii	22
Quasispecies of SARS-CoV-2 revealed by single nucleotide polymorphisms (SNPs) analysis	21
Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments	21
MoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae	21
Hypervirulent and hypermucoviscous extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Klebsiella variicola in Chile	21
Phenol-soluble modulins α are major virulence factors of Staphylococcus aureus secretome promoting inflammatory response in human epidermis	21
The pathogenicity and virulence of Leishmania - interplay of virulence factors with host defenses	21
Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India	21
Mitigating the threat of emerging infectious diseases; a coevolutionary perspective	20
“Core” RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?	20
Novel therapeutic strategies for chronic hepatitis B	20

Roborovski hamster (Phodopus roborovskii) strain SH101 as a systemic infection model of SARS-CoV-2	20
Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments	20
Methicillin-resistant Staphylococcus aureus from infected skin lesions present several virulence genes and are associated with the CC30 in Brazilian children with atopic dermatitis	20
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii	20
Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes	19
A systematic review of the epidemiology of Hepatitis E virus infection in South – Eastern Asia	19
Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients	19
The lipoprotein NlpD in Cronobacter sakazakii responds to acid stress and regulates macrophage resistance and virulence by maintaining membrane integrity	19
A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China	18
Evaluation of hepatitis E antigen kinetics and its diagnostic utility for prediction of the outcomes of hepatitis E virus genotype 1 infection	18
The leptospiral LipL21 and LipL41 proteins exhibit a broad spectrum of interactions with host cell components	18
The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences	18
Pathogenicity and virulence of Rickettsia	18
Two-component systems regulate bacterial virulence in response to the host gastrointestinal environment and metabolic cues	18
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture	18
Talaromyces marneffei promotes M2-like polarization of human macrophages by downregulating SOCS3 expression and activating the TLR9 pathway	18
Bordetella bronchiseptica promotes adherence, colonization, and cytotoxicity of Streptococcus suis in a porcine precision-cut lung slice model	17
Establishing an invertebrate Galleria mellonella greater wax moth larval model of Neisseria gonorrhoeae infection	17
The two-component signal transduction system and its regulation in Candida albicans	17
A novel transcription factor UvCGBP1 regulates development and virulence of rice false smut fungus Ustilaginoidea virens	17
UvKmt6-mediated H3K27 trimethylation is required for development, pathogenicity, and stress response in Ustilaginoidea virens	16
Pathogenicity and virulence ofBurkholderia pseudomallei	16
Set2 family regulates mycotoxin metabolism and virulence via H3K36 methylation in pathogenic fungus Aspergillus flavus	16
Whole genome analysis unveils genetic diversity and potential virulence determinants in Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Paci	16
Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts	16
The PirB toxin protein from Vibrio parahaemolyticus induces apoptosis in hemocytes of Penaeus vannamei	16
SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates ofStaphylococcus aureusLAC and UAMS-1	16
Genetic architecture of transmission stage production and virulence in schistosome parasites	16
Genomic and phenotypic analyses of multidrug-resistant Acinetobacter baumannii NCCP 16007 isolated from a patient with a urinary tract infection	16
Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications	16
Candida auris infections in China	16
Koi sleepy disease as a pathophysiological and immunological consequence of a branchial infection of common carp with carp edema virus	15
Novel biomarkers for the prediction of COVID-19 progression a retrospective, multi-center cohort study	15
Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin	15
Oral vaccination with recombinant Lactobacillus casei expressing Aeromonas hydrophila Aha1 against A. hydrophila infections in common carps	15
Vagus nerve plays a pivotal role in CD4+ T cell differentiation during CVB3-induced murine acute myocarditis	15
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions	15
Identification of Streptococcus suis putative zoonotic virulence factors: A systematic review and genomic meta-analysis	15
Oral administration of Clostridium butyricum rescues streptomycin-exacerbated respiratory syncytial virus-induced lung inflammation in mice	14
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking	14
Fructose promotes ampicillin killing of antibiotic-resistant Streptococcus agalactiae	14
Pathogenicity and virulence of Acinetobacter baumannii : Factors contributing to the fitness in healthcare settings and the infected host	14
Time-dependent viral interference between influenza virus and coronavirus in the infection of differentiated porcine airway epithelial cells	14
The antimicrobial systems of Streptococcus suis promote niche competition in pig tonsils	14
Pseudomonas aeruginosa adaptation in cystic fibrosis patients increases C5a levels and promotes neutrophil recruitment	14
A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of methicillin-resistant Staphylococcus aureus through distinct mechanisms	14
Helicobacter pylori GmhB enzyme involved in ADP-heptose biosynthesis pathway is essential for lipopolysaccharide biosynthesis and bacterial virulence	14
Complement receptor 3 mediatesAspergillus fumigatusinternalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK	14
Infection of polarized bovine respiratory epithelial cells by bovine viral diarrhea virus (BVDV)	14
Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks	14
Plant pathogens provide clues to the potential origin of bat white-nose syndrome Pseudogymnoascus destructans	14
Clinical characteristics of asymptomatic carriers of novel coronavirus disease 2019: A multi-center study in Jiangsu Province	13
Sodium houttuyfonate enhances the mono-therapy of fluconazole on oropharyngeal candidiasis (OPC) through HIF-1α/IL-17 axis by inhibiting cAMP mediated filamentation in Candida albicans-Candida glab	13
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration	13
Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection	13
Catalase impairs Leishmania mexicana development and virulence	13
Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model	13
Lipid larceny: channelizing host lipids for establishing successful pathogenesis by bacteria	13
Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity	13
Luteolin decreases the pathogenicity of Aeromonas hydrophila via inhibiting the activity of aerolysin	13
Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli from Egyptian children with diarrhoea: Similarities and differences	13
Role of cell membrane homeostasis in the pathogenicity of pathogenic filamentous fungi	13
Two functionally distinct heme/iron transport systems are virulence determinants of the fish pathogen Flavobacterium psychrophilum	13
A novel phosphoinositide kinase Fab1 regulates biosynthesis of pathogenic aflatoxin in Aspergillus flavus	13
Defective phagocyte association during infection of Galleria mellonella with Yersinia pseudotuberculosis is detrimental to both insect host and microbe	13
Artemisinin displays bactericidal activity via copper-mediated DNA damage	12
An important call: Suggestion of using IL-10 as therapeutic agent for COVID-19 with ARDS and other complications	12
DIM5/KMT1 controls fungal insect pathogenicity and genome stability by methylation of histone H3K4, H3K9 and H3K36	12
Vibrio splendidus virulence to Apostichopus japonicus is mediated by hppD through glutamate metabolism and flagellum assembly	12
Time-resolved analysis of Staphylococcus aureus invading the endothelial barrier	12
ABO blood group is involved in the quality of the specific immune response anti-SARS-CoV-2	12
The Superior Adherence Phenotype of E. coli O104:H4 is Directly Mediated by the Aggregative Adherence Fimbriae Type I	12
Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection	12
The involvement of the Candida glabrata trehalase enzymes in stress resistance and gut colonization	12
Staphylococcus aureus N-terminus formylated δ-toxin tends to form amyloid fibrils, while the deformylated δ-toxin tends to form functional oligomer complexes	12
Pathogenicity and virulence of human adenovirus F41: Possible links to severe hepatitis in children	12
Association of follicular helper T and follicular regulatory T cells with severity and hyperglycemia in hospitalized COVID-19 patients	12
Comprehensive analysis of lncRNA expression profiles in cytopathic biotype BVDV-infected MDBK cells provides an insight into biological contexts of host–BVDV interactions	12
Aeromonas hydrophila inhibits autophagy triggering cytosolic translocation of mtDNA which activates the pro-apoptotic caspase-1/IL-1β-nitric oxide axis in headkidney macrophages	12