OOIR: Observatory of International Research

Papers

(The TQCC of Virulence is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-09-01 to 2024-09-01.)

Article	Citations
Pathogenicity and virulence of Staphylococcus aureus	596
Pathogenesis and virulence of Candida albicans	160
COVID-19 evolution during the pandemic – Implications of new SARS-CoV-2 variants on disease control and public health policies	137
Pathogenesis and virulence of herpes simplex virus	133
Pathogenicity and virulence of Clostridium perfringens	111
Pathogenicity and virulence of Listeria monocytogenes: A trip from environmental to medical microbiology	79
Immune dysregulation and system pathology in COVID-19	76
Hypervirulent Klebsiella pneumoniae is emerging as an increasingly prevalent K. pneumoniae pathotype responsible for nosocomial and healthcare-associated infections in Beijing, China	73
Seroprevalence of SARS-CoV-2 (COVID-19) exposure in pet cats and dogs in Minnesota, USA	68
Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage	67
Pathogenicity and Virulence ofLegionella: Intracellular replication and host response	63
Pathogenicity and virulence of the liver flukesFasciola hepaticaandFasciolaGiganticathat cause the zoonosis Fasciolosis	55
Pathogenicity and virulence of Marburg virus	55
Pathogenicity and virulence of Mycobacterium tuberculosis	46
The pathogenicity and virulence of Toxoplasma gondii	45
Pathogenesis and virulence of flavivirus infections	44
Transcriptomic analyses reveal comprehensive responses of insect hemocytes to mycopathogen Beauveria bassiana, and fungal virulence-related cell wall protein assists pathogen to evade host cellular de	43
An Organ System-Based Synopsis ofPseudomonas aeruginosaVirulence	42
Pathogenicity and virulence of Clostridioides difficile	42
Glycosylation of viral proteins: Implication in virus–host interaction and virulence	41
Therapeutic implications of C. albicans-S. aureus mixed biofilm in a murine subcutaneous catheter model of polymicrobial infection	41
Understanding the prevalence of SARS-CoV-2 (COVID-19) exposure in companion, captive, wild, and farmed animals	39
Antimicrobial photodynamic therapy (aPDT) for biofilm treatments. Possible synergy between aPDT and pulsed electric fields	37
Pathogenicity & virulence ofMycoplasma hyopneumoniae	36
Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus	36

Genetic diversity and evolution of the virulence plasmids encoding aerobactin and salmochelin in Klebsiella pneumoniae	36
Functional analysis of seven regulators of G protein signaling (RGSs) in the nematode-trapping fungus Arthrobotrys oligospora	35
Paeoniflorin reduce luxS/AI-2 system-controlled biofilm formation and virulence in Streptococcus suis	33
Pathogenicity and virulence of Hepatitis B virus	33
The hypermucoviscosity of hypervirulent K. pneumoniae confers the ability to evade neutrophil-mediated phagocytosis	33
AP-1 signaling pathway promotes pro-IL-1β transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection	33
Infection strategies of mycoplasmas: Unraveling the panoply of virulence factors	33
Virulence ofCandida aurisfrom different clinical origins inCaenorhabditis elegansandGalleria mellonellahost models	32
Pathogenicity and virulence regulation of Vibrio cholerae at the interface of host-gut microbiome interactions	32
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris	32
Pathogenicity and virulence ofStreptococcus pneumoniae: Cutting to the chase on proteases	32
Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host	31
The pathogenesis and virulence of enterovirus-D68 infection	31
A serious skin virus epidemic sweeping through the Indian subcontinent is a threat to the livelihood of farmers	30
Persistent low-Level viremia in persons living with HIV undertreatment: An unresolved status	29
Convergence of carbapenem resistance and hypervirulence in a highly-transmissible ST11 clone of K. pneumoniae: An epidemiological, genomic and functional study	29
Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity	29
The battle for autophagy between host and influenza A virus	29
A clubroot pathogen effector targets cruciferous cysteine proteases to suppress plant immunity	29
YjbH regulates virulence genes expression and oxidative stress resistance in Staphylococcus aureus	27
Synergy of alanine and gentamicin to reduce nitric oxide for elevating killing efficacy to antibiotic-resistant Vibrio alginolyticus	27
Contribution of hypoxia inducible factor-1 during viral infections	27
Host Defence RNases as Antiviral Agents against Enveloped Single Stranded RNA Viruses	26
Versatile lifestyles of Edwardsiella: Free-living, pathogen, and core bacterium of the aquatic resistome	26
Pathogenicity and virulence of hepatitis A virus	26
Distribution and antifungal susceptibility pattern ofCandidaspecies from mainland China: A systematic analysis	26
The African swine fever virus protease pS273R inhibits DNA sensing cGAS-STING pathway by targeting IKKε	26
Domain in Fiber-2 interacted with KPNA3/4 significantly affects the replication and pathogenicity of the highly pathogenic FAdV-4	26
Pathogenicity and virulence of influenza	26
Zika virus NS2A inhibits interferon signaling by degradation of STAT1 and STAT2	25
Pathogenicity and virulence of Entamoeba histolytica , the agent of amoebiasis	25
Review of human pegivirus: Prevalence, transmission, pathogenesis, and clinical implication	25
Aprepitant, an antiemetic agent, interferes with metal ion homeostasis ofCandida aurisand displays potent synergistic interactions with azole drugs	25
Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model	23
Pathogenicity and virulence of West Nile virus revisited eight decades after its first isolation	23
Pathogenicity and virulence of Aspergillus fumigatus	22
Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A	22
Shewanellainfection in humans: Epidemiology, clinical features and pathogenicity	22
MSS2 maintains mitochondrial function and is required for chitosan resistance, invasive growth, biofilm formation and virulence in Candida albicans	22
Pathogenicity and virulence of Mycobacterium leprae	21
The pathogenicity and virulence of Leishmania - interplay of virulence factors with host defenses	21
Hypervirulent and hypermucoviscous extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Klebsiella variicola in Chile	21
Pathogenicity and virulence of Clostridium botulinum	21
MoSec61β, the beta subunit of Sec61, is involved in fungal development and pathogenicity, plant immunity, and ER-phagy in Magnaporthe oryzae	21
Intracellular persistence of Staphylococcus aureus in endothelial cells is promoted by the absence of phenol-soluble modulins	21
Quasispecies of SARS-CoV-2 revealed by single nucleotide polymorphisms (SNPs) analysis	21
Classical swine fever virus employs the PERK- and IRE1-dependent autophagy for viral replication in cultured cells.	20
Importance of twitching and surface-associated motility in the virulence of Acinetobacter baumannii	20
Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments	20
Mitigating the threat of emerging infectious diseases; a coevolutionary perspective	20

Evaluation of the safety, immunogenicity and efficacy of a new live-attenuated lumpy skin disease vaccine in India	20
“Core” RxLR effectors in phytopathogenic oomycetes: A promising way to breeding for durable resistance in plants?	20
Phenol-soluble modulins α are major virulence factors of Staphylococcus aureus secretome promoting inflammatory response in human epidermis	20
Methicillin-resistant Staphylococcus aureus from infected skin lesions present several virulence genes and are associated with the CC30 in Brazilian children with atopic dermatitis	20
Virulence role of the outer membrane protein CarO in carbapenem-resistant Acinetobacter baumannii	20
Novel therapeutic strategies for chronic hepatitis B	19
Pathogenicity & virulence of Histoplasma capsulatum - A multifaceted organism adapted to intracellular environments	19
Roborovski hamster (Phodopus roborovskii) strain SH101 as a systemic infection model of SARS-CoV-2	19
A systematic review of the epidemiology of Hepatitis E virus infection in South – Eastern Asia	19
Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients	19
Two-component systems regulate bacterial virulence in response to the host gastrointestinal environment and metabolic cues	18
The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences	18
Evaluation of hepatitis E antigen kinetics and its diagnostic utility for prediction of the outcomes of hepatitis E virus genotype 1 infection	18
Talaromyces marneffei promotes M2-like polarization of human macrophages by downregulating SOCS3 expression and activating the TLR9 pathway	18
Adaptation of the emerging pathogenic yeast Candida auris to high caspofungin concentrations correlates with cell wall changes	18
The leptospiral LipL21 and LipL41 proteins exhibit a broad spectrum of interactions with host cell components	18
CRISPR-cas system in the acquisition of virulence genes in dental-root canal and hospital-acquired isolates of Enterococcus faecalis	18
A virulent Bacillus cereus strain from deep-sea cold seep induces pyroptosis in a manner that involves NLRP3 inflammasome, JNK pathway, and lysosomal rupture	18
Pathogenicity and virulence of Rickettsia	17
A biological and genomic comparison of a drug-resistant and a drug-susceptible strain of Candida auris isolated from Beijing, China	17
The lipoprotein NlpD in Cronobacter sakazakii responds to acid stress and regulates macrophage resistance and virulence by maintaining membrane integrity	17
UvKmt6-mediated H3K27 trimethylation is required for development, pathogenicity, and stress response in Ustilaginoidea virens	16
Bordetella bronchiseptica promotes adherence, colonization, and cytotoxicity of Streptococcus suis in a porcine precision-cut lung slice model	16
Establishing an invertebrate Galleria mellonella greater wax moth larval model of Neisseria gonorrhoeae infection	16
Whole genome analysis unveils genetic diversity and potential virulence determinants in Vibrio parahaemolyticus associated with disease outbreak among cultured Litopenaeus vannamei (Paci	16
Genomic and phenotypic analyses of multidrug-resistant Acinetobacter baumannii NCCP 16007 isolated from a patient with a urinary tract infection	16
The PirB toxin protein from Vibrio parahaemolyticus induces apoptosis in hemocytes of Penaeus vannamei	16
Nucleolar protein NPM1 is essential for circovirus replication by binding to viral capsid	16
Pathogenicity and virulence ofBurkholderia pseudomallei	16
Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications	16
SarA plays a predominant role in controlling the production of extracellular proteases in the diverse clinical isolates ofStaphylococcus aureusLAC and UAMS-1	16
Sirtuin 3 is essential for host defense against Mycobacterium abscessus infection through regulation of mitochondrial homeostasis	15
The two-component signal transduction system and its regulation in Candida albicans	15
Candida albicans adhesion to central venous catheters: Impact of blood plasma-driven germ tube formation and pathogen-derived adhesins	15
Emergent SARS-CoV-2 variants: comparative replication dynamics and high sensitivity to thapsigargin	15
Set2 family regulates mycotoxin metabolism and virulence via H3K36 methylation in pathogenic fungus Aspergillus flavus	15
Candida auris infections in China	15
Vagus nerve plays a pivotal role in CD4+ T cell differentiation during CVB3-induced murine acute myocarditis	15
Pathogenicity and virulence of malaria: Sticky problems and tricky solutions	15
Oral vaccination with recombinant Lactobacillus casei expressing Aeromonas hydrophila Aha1 against A. hydrophila infections in common carps	15
Identification of Streptococcus suis putative zoonotic virulence factors: A systematic review and genomic meta-analysis	15
Fructose promotes ampicillin killing of antibiotic-resistant Streptococcus agalactiae	14
Plant pathogens provide clues to the potential origin of bat white-nose syndrome Pseudogymnoascus destructans	14
Oral administration of Clostridium butyricum rescues streptomycin-exacerbated respiratory syncytial virus-induced lung inflammation in mice	14
Complement receptor 3 mediates Aspergillus fumigatus internalization into alveolar epithelial cells with the increase of intracellular phosphatidic acid by activating FAK	14
Dynamic Dissection of Dynein and Kinesin-1 Cooperatively Mediated Intercellular Transport of Porcine Epidemic Diarrhea Coronavirus along Microtubule Using Single Virus Tracking	14
Reliability of induced sputum test is greater than that of throat swab test for detecting SARS-CoV-2 in patients with COVID-19: A multi-center cross-sectional study	14
Sox4 represses host innate immunity to facilitate pathogen infection by hijacking the TLR signaling networks	14
Helicobacter pylori GmhB enzyme involved in ADP-heptose biosynthesis pathway is essential for lipopolysaccharide biosynthesis and bacterial virulence	14
Genetic architecture of transmission stage production and virulence in schistosome parasites	14
The antimicrobial systems of Streptococcus suis promote niche competition in pig tonsils	14
Koi sleepy disease as a pathophysiological and immunological consequence of a branchial infection of common carp with carp edema virus	14
Pseudomonas aeruginosa adaptation in cystic fibrosis patients increases C5a levels and promotes neutrophil recruitment	14
Shorter incubation period is associated with severe disease progression in patients with COVID-19	14
Time-dependent viral interference between influenza virus and coronavirus in the infection of differentiated porcine airway epithelial cells	14
A novel transcription factor UvCGBP1 regulates development and virulence of rice false smut fungus Ustilaginoidea virens	14
Pathogenicity and virulence of African trypanosomes: From laboratory models to clinically relevant hosts	14
Catalase impairs Leishmania mexicana development and virulence	13
Clinical characteristics of asymptomatic carriers of novel coronavirus disease 2019: A multi-center study in Jiangsu Province	13
Lipid larceny: channelizing host lipids for establishing successful pathogenesis by bacteria	13
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration	13
P-type Na⁺/K⁺ ATPases essential and nonessential for cellular homeostasis and insect pathogenicity of Beauveria bassiana	13
Exploration of turn-positive RT-PCR results and factors related to treatment outcome in COVID-19: A retrospective cohort study	13
Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli from Egyptian children with diarrhoea: Similarities and differences	13
Infection of polarized bovine respiratory epithelial cells by bovine viral diarrhea virus (BVDV)	13
Novel biomarkers for the prediction of COVID-19 progression a retrospective, multi-center cohort study	13
A novel phosphoinositide kinase Fab1 regulates biosynthesis of pathogenic aflatoxin in Aspergillus flavus	13
Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity	13
Luteolin decreases the pathogenicity of Aeromonas hydrophila via inhibiting the activity of aerolysin	13
Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model	13
Sodium houttuyfonate enhances the mono-therapy of fluconazole on oropharyngeal candidiasis (OPC) through HIF-1α/IL-17 axis by inhibiting cAMP mediated filamentation in Candida albicans-Candida glab	13
Two functionally distinct heme/iron transport systems are virulence determinants of the fish pathogen Flavobacterium psychrophilum	13
A temperate Siphoviridae bacteriophage isolate from Siberian tiger enhances the virulence of methicillin-resistant Staphylococcus aureus through distinct mechanisms	13
Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection	13
Defective phagocyte association during infection of Galleria mellonella with Yersinia pseudotuberculosis is detrimental to both insect host and microbe	13